		Clinical Features	Time to Death		AGE		PRIMARY.SITE.OF.DISEASE		GENDER		DISTANT.METASTASIS		LYMPH.NODE.METASTASIS		TUMOR.STAGECODE		NEOPLASM.DISEASESTAGE	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	t-test_P	t-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Chi-square test_P	Chi-square test_Q	Chi-square test_P	Chi-square test_Q	t-test_P	t-test_Q	Chi-square test_P	Chi-square test_Q
TP53	25 (16%)	134	0.66644	1	0.091888	1	0.24249	1	0.82467	1	0.57745	1	0.31841	1	NA	NA	0.30838	1
BRAF	80 (50%)	79	0.19675	1	0.076342	1	0.095552	1	0.74492	1	0.55411	1	0.75159	1	NA	NA	0.78708	1
C15ORF23	11 (7%)	148	0.64805	1	0.66349	1	0.81839	1	0.5367	1	0.96899	1	0.40575	1	NA	NA	0.69343	1
CDKN2A	25 (16%)	134	0.56317	1	0.92248	1	0.62412	1	1	1	0.84652	1	0.59923	1	NA	NA	0.6029	1
NRAS	48 (30%)	111	0.66393	1	0.44182	1	0.33021	1	1	1	0.62105	1	0.88468	1	NA	NA	0.52262	1
OXA1L	4 (3%)	155	0.77004	1	0.80052	1	0.59334	1	0.63292	1	0.99492	1	0.70572	1	NA	NA	0.45371	1
STK19	9 (6%)	150	0.38082	1	0.50639	1	1	1	0.29942	1	0.97999	1	0.83332	1	NA	NA	0.91701	1
PTEN	13 (8%)	146	0.71932	1	0.23877	1	0.47193	1	0.55824	1	0.00032143	0.28	0.75872	1	NA	NA	0.028111	1
RAC1	11 (7%)	148	0.086587	1	0.51249	1	0.412	1	1	1	0.97478	1	0.90626	1	NA	NA	0.35763	1
ACSM2B	29 (18%)	130	0.38263	1	0.94231	1	0.087236	1	0.0029074	1	0.79381	1	0.64693	1	NA	NA	0.77465	1
CADM2	17 (11%)	142	0.46722	1	0.92848	1	0.52469	1	1	1	0.91329	1	0.57656	1	NA	NA	0.3161	1
OR51S1	16 (10%)	143	0.62126	1	0.51396	1	0.18531	1	1	1	0.94031	1	0.37992	1	NA	NA	0.1379	1
LCE1B	10 (6%)	149	0.4645	1	0.66554	1	0.09118	1	0.50475	1	0.97478	1	0.27134	1	NA	NA	0.69054	1
IDH1	7 (4%)	152	0.70462	1	0.011143	1	1	1	0.42714	1	0.98462	1	0.89662	1	NA	NA	0.51707	1
TAF1A	11 (7%)	148	0.072398	1	0.83057	1	0.73811	1	0.33382	1	0.23406	1	0.74911	1	NA	NA	0.83139	1
NAP1L2	15 (9%)	144	0.26436	1	0.077199	1	0.093537	1	0.57697	1	0.94031	1	0.36723	1	NA	NA	0.46744	1
MUC7	11 (7%)	148	0.36082	1	0.00021487	0.187	0.81839	1	0.5367	1	0.96264	1	0.76424	1	NA	NA	0.60494	1
PPP6C	14 (9%)	145	0.0066635	1	0.4948	1	0.72808	1	1	1	0.37006	1	0.34661	1	NA	NA	0.57358	1
FRG2B	10 (6%)	149	0.64921	1	0.021982	1	0.80621	1	0.50475	1	0.96899	1	0.87132	1	NA	NA	0.61924	1
USP29	27 (17%)	132	0.1407	1	0.055762	1	0.64456	1	0.19535	1	0.84652	1	0.60322	1	NA	NA	0.26854	1
PRB4	17 (11%)	142	0.062938	1	0.16451	1	0.36847	1	0.29058	1	0.40955	1	0.62902	1	NA	NA	0.8357	1
HIST1H2AA	7 (4%)	152	0.76703	1	0.97093	1	0.040006	1	1	1	0.98462	1	0.92303	1	NA	NA	0.73979	1
RPTN	26 (16%)	133	0.29704	1	0.21241	1	0.064342	1	0.5102	1	0.84652	1	0.23284	1	NA	NA	0.014007	1
ZNF479	13 (8%)	146	0.23567	1	0.18457	1	0.55604	1	0.55824	1	0.28172	1	0.74356	1	NA	NA	0.91328	1
C8A	20 (13%)	139	0.42699	1	0.13996	1	1	1	0.089862	1	0.080258	1	0.95451	1	NA	NA	0.13565	1
FUT9	17 (11%)	142	0.4975	1	0.02869	1	0.38809	1	1	1	0.91329	1	0.62242	1	NA	NA	0.11493	1
ZNF679	15 (9%)	144	0.84893	1	0.43015	1	0.088368	1	0.78654	1	0.94031	1	0.70712	1	NA	NA	0.45496	1
NRK	20 (13%)	139	0.99023	1	0.72469	1	0.52749	1	0.62256	1	0.89283	1	0.70951	1	NA	NA	0.5297	1
CDH9	26 (16%)	133	0.2886	1	0.45365	1	0.016761	1	1	1	0.8209	1	0.44459	1	NA	NA	0.070977	1
PRAMEF11	15 (9%)	144	0.039416	1	0.082868	1	0.74723	1	1	1	0.94031	1	0.035786	1	NA	NA	0.85643	1
DDX3X	16 (10%)	143	0.57215	1	0.52993	1	0.53725	1	0.1117	1	0.0050422	1	0.97652	1	NA	NA	0.68282	1
GRXCR1	15 (9%)	144	0.18916	1	0.027954	1	0.51398	1	0.78654	1	0.94031	1	0.69368	1	NA	NA	0.29636	1
PRB2	22 (14%)	137	0.59391	1	0.008591	1	0.19307	1	0.056783	1	0.8819	1	0.69089	1	NA	NA	0.13792	1
ELF5	5 (3%)	154	0.15658	1	0.5246	1	0.65355	1	0.65068	1	0.99492	1	0.086255	1	NA	NA	0.87123	1
IL32	7 (4%)	152	0.035262	1	0.70699	1	0.53104	1	1	1	0.98462	1	0.75905	1	NA	NA	0.01044	1
LUZP2	13 (8%)	146	0.81158	1	0.81355	1	0.037787	1	0.55824	1	0.95574	1	0.70817	1	NA	NA	0.020341	1
PDE1A	24 (15%)	135	0.6217	1	0.20086	1	0.019198	1	0.81966	1	0.85873	1	0.20781	1	NA	NA	0.63905	1
RBM11	10 (6%)	149	0.56408	1	0.27302	1	0.89127	1	0.7437	1	0.18557	1	0.62837	1	NA	NA	0.60403	1
GLRB	18 (11%)	141	0.51755	1	0.24831	1	0.018238	1	0.79923	1	0.90329	1	0.76034	1	NA	NA	0.62692	1
PRB1	15 (9%)	144	0.55456	1	0.36507	1	1	1	0.050182	1	0.94829	1	0.43966	1	NA	NA	0.50411	1
KIAA1257	7 (4%)	152	0.21664	1	0.32984	1	0.53104	1	0.25559	1	0.99209	1	0.81644	1	NA	NA	0.54667	1
USP17L2	15 (9%)	144	0.89524	1	0.80186	1	0.046215	1	0.1689	1	0.94031	1	0.78009	1	NA	NA	0.14868	1
SPAG16	13 (8%)	146	0.2268	1	0.51611	1	0.92184	1	0.37318	1	0.96264	1	0.80527	1	NA	NA	0.67532	1
OR4M2	17 (11%)	142	0.65619	1	0.086576	1	0.14714	1	0.79469	1	0.44562	1	0.94065	1	NA	NA	0.26579	1
GFRAL	21 (13%)	138	0.95834	1	0.90176	1	0.22025	1	0.81015	1	0.53376	1	0.41049	1	NA	NA	0.20187	1
UNC119B	3 (2%)	156	0.99117	1	0.37666	1	1	1	1	1	0.99713	1	0.97855	1	NA	NA	0.59466	1
PHGDH	7 (4%)	152	0.67854	1	0.85927	1	0.74226	1	0.045373	1	0.99209	1	0.96628	1	NA	NA	0.098684	1
STXBP5L	32 (20%)	127	0.27333	1	0.52763	1	0.36174	1	0.68958	1	0.79381	1	0.91894	1	NA	NA	0.30951	1
TRAT1	10 (6%)	149	0.02788	1	0.6835	1	0.051316	1	0.50475	1	0.97478	1	0.63906	1	NA	NA	0.79944	1
ZNF844	4 (3%)	155	0.35208	1	0.020009	1	0.43707	1	0.63292	1	0.99492	1	0.43989	1	NA	NA	0.81252	1
TTN	123 (77%)	36	0.32495	1	0.67319	1	1	1	0.1171	1	0.57315	1	0.29938	1	NA	NA	0.37193	1
COPG2	3 (2%)	156	0.46147	1	0.99398	1	0.72298	1	1	1	0.99713	1	0.97855	1	NA	NA	0.05391	1
DSG3	34 (21%)	125	0.85192	1	0.23879	1	0.26413	1	0.55154	1	0.18884	1	0.77257	1	NA	NA	0.50963	1
GML	8 (5%)	151	0.91816	1	0.11235	1	1	1	0.26026	1	0.98462	1	0.66911	1	NA	NA	0.96491	1
HHLA2	10 (6%)	149	0.66277	1	0.3914	1	0.17141	1	0.7437	1	0.97478	1	0.41806	1	NA	NA	0.92656	1
LILRB4	23 (14%)	136	0.51356	1	0.65343	1	0.058846	1	0.81966	1	0.16886	1	0.65739	1	NA	NA	0.46495	1
SLC38A4	19 (12%)	140	0.91977	1	0.49162	1	0.19399	1	0.043436	1	0.91329	1	0.98242	1	NA	NA	0.94904	1
OR2L3	12 (8%)	147	0.90367	1	0.75711	1	0.13091	1	0.7656	1	0.012855	1	0.68881	1	NA	NA	0.012457	1
HBD	8 (5%)	151	0.12607	1	0.6152	1	0.38468	1	0.47695	1	0.97999	1	0.89029	1	NA	NA	0.41254	1
TBC1D3B	3 (2%)	156	0.0031147	1	0.40207	1	0.283	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
TCEB3C	23 (14%)	136	0.35043	1	0.46459	1	0.82541	1	0.10589	1	0.85873	1	0.45969	1	NA	NA	0.42322	1
CYLC2	16 (10%)	143	0.50574	1	0.09609	1	0.81616	1	0.78654	1	0.94829	1	0.075039	1	NA	NA	0.52769	1
HBG2	6 (4%)	153	0.53589	1	0.2453	1	0.48605	1	1	1	0.98866	1	0.95493	1	NA	NA	0.73629	1
LOC649330	18 (11%)	141	0.50767	1	0.017557	1	0.69488	1	0.44398	1	0.93181	1	0.85799	1	NA	NA	0.73589	1
PARM1	13 (8%)	146	0.22978	1	0.31036	1	0.20557	1	0.76783	1	0.95574	1	0.036668	1	NA	NA	0.32824	1
CCK	5 (3%)	154	0.11026	1	0.71917	1	0.65355	1	0.65068	1	0.99492	1	0.015764	1	NA	NA	0.75483	1
ZFP106	6 (4%)	153	0.52387	1	0.00058844	0.512	0.48605	1	0.083893	1	0.98866	1	0.72535	1	NA	NA	0.3787	1
UGT2B15	15 (9%)	144	0.61259	1	0.41536	1	0.92634	1	0.1689	1	0.068631	1	0.64593	1	NA	NA	0.064185	1
DSG1	24 (15%)	135	0.1092	1	0.85874	1	0.757	1	1	1	0.85873	1	0.5383	1	NA	NA	0.38712	1
ARL16	5 (3%)	154	0.20927	1	0.026529	1	0.057916	1	0.65068	1	0.99209	1	0.83048	1	NA	NA	0.15431	1
VEGFC	15 (9%)	144	0.88239	1	0.76978	1	0.42302	1	0.57697	1	0.94829	1	0.16764	1	NA	NA	0.23601	1
PSG4	16 (10%)	143	0.85513	1	0.52667	1	0.081091	1	1	1	0.94031	1	0.91263	1	NA	NA	0.74985	1
DEFB119	6 (4%)	153	0.19274	1	0.19065	1	0.15191	1	1	1	0.99209	1	0.9063	1	NA	NA	0.33887	1
KLHL4	15 (9%)	144	0.083647	1	0.95185	1	0.21335	1	0.57697	1	0.95574	1	0.85716	1	NA	NA	0.4833	1
EIF3D	3 (2%)	156	0.0486	1	0.47872	1	0.72298	1	0.29066	1	0.99713	1	0.94791	1	NA	NA	0.62472	1
OR2W1	12 (8%)	147	0.61556	1	0.073787	1	0.83296	1	0.371	1	0.96264	1	0.23301	1	NA	NA	0.87399	1
OR4N2	18 (11%)	141	0.8545	1	0.44148	1	0.15775	1	0.01802	1	0.066014	1	0.90053	1	NA	NA	0.4689	1
CCDC11	15 (9%)	144	0.56793	1	0.67899	1	0.16635	1	0.78654	1	0.94031	1	0.98235	1	NA	NA	0.48585	1
LIN7A	8 (5%)	151	0.56232	1	0.71545	1	0.38468	1	0.71108	1	0.98866	1	0.94356	1	NA	NA	0.54323	1
RAPGEF5	7 (4%)	152	0.91659	1	0.47897	1	0.077662	1	0.25559	1	0.99209	1	0.37761	1	NA	NA	0.80629	1
CD2	14 (9%)	145	0.44637	1	0.33787	1	0.042175	1	0.7749	1	0.068631	1	0.90905	1	NA	NA	0.34732	1
C2ORF40	4 (3%)	155	0.8469	1	0.40053	1	0.063861	1	0.63292	1	0.99713	1	0.96012	1	NA	NA	NA	NA
SGCZ	16 (10%)	143	0.20518	1	0.66914	1	0.93006	1	1	1	0.96264	1	0.35581	1	NA	NA	0.76174	1
SPANXN2	13 (8%)	146	0.037639	1	0.50982	1	0.6528	1	0.76783	1	0.96264	1	0.37417	1	NA	NA	0.28799	1
TLL1	31 (19%)	128	0.87343	1	0.25019	1	0.3258	1	0.54065	1	0.66981	1	0.31968	1	NA	NA	0.24504	1
C9ORF119	5 (3%)	154	0.82774	1	0.9608	1	1	1	0.15761	1	0.99209	1	0.07299	1	NA	NA	0.79915	1
CCDC54	10 (6%)	149	0.38601	1	0.66985	1	0.41457	1	0.32152	1	0.97999	1	0.97455	1	NA	NA	0.90449	1
DEFB118	6 (4%)	153	0.12019	1	0.45387	1	0.84131	1	1	1	0.98866	1	0.98353	1	NA	NA	0.77802	1
HTR3B	11 (7%)	148	0.052059	1	0.62939	1	0.33561	1	0.20983	1	0.96899	1	0.79924	1	NA	NA	0.39416	1
MARCH11	7 (4%)	152	0.26472	1	0.98616	1	0.14212	1	0.71108	1	0.056169	1	0.92303	1	NA	NA	0.58053	1
MKX	10 (6%)	149	0.40834	1	0.81216	1	0.065931	1	0.7437	1	0.98462	1	0.92303	1	NA	NA	0.021625	1
OR5H2	11 (7%)	148	0.34237	1	0.029344	1	0.90267	1	0.74862	1	0.96264	1	0.39563	1	NA	NA	0.40927	1
SIGLEC14	7 (4%)	152	0.79141	1	0.07644	1	0.068158	1	0.045373	1	0.98866	1	0.98353	1	NA	NA	0.37288	1
TUBB8	7 (4%)	152	0.78064	1	0.21553	1	1	1	0.71108	1	0.99209	1	0.96628	1	NA	NA	0.66489	1
ZIM3	14 (9%)	145	0.038535	1	0.81896	1	0.024651	1	0.25305	1	0.95574	1	0.43216	1	NA	NA	0.25924	1
PRC1	9 (6%)	150	0.63663	1	0.44986	1	0.55109	1	0.48482	1	0.97999	1	0.6366	1	NA	NA	0.93314	1
MUM1L1	16 (10%)	143	0.43876	1	0.81604	1	0.44334	1	1	1	0.9228	1	0.43001	1	NA	NA	0.60735	1
TRIM58	12 (8%)	147	0.30741	1	0.0025119	1	0.83296	1	1	1	0.96264	1	0.7963	1	NA	NA	0.79431	1
ANKRD20A4	3 (2%)	156	0.51158	1	0.83075	1	1	1	0.29066	1	0.99713	1	0.96012	1	NA	NA	0.59466	1
OR5J2	10 (6%)	149	0.72573	1	0.90565	1	0.89127	1	0.17938	1	0.97999	1	0.9494	1	NA	NA	0.81806	1
CLEC14A	14 (9%)	145	0.2025	1	0.77144	1	1	1	0.25305	1	0.96264	1	0.48284	1	NA	NA	0.48141	1
FAM19A1	7 (4%)	152	0.42874	1	0.95998	1	1	1	1	1	0.98866	1	0.68385	1	NA	NA	0.83445	1
GK2	20 (13%)	139	0.23936	1	0.84159	1	0.074264	1	0.81032	1	0.90329	1	0.34746	1	NA	NA	0.043387	1
LONRF2	13 (8%)	146	0.019749	1	0.89605	1	0.55604	1	0.76783	1	0.97478	1	0.22873	1	NA	NA	0.41808	1
HAPLN1	8 (5%)	151	0.33284	1	0.16174	1	0.8739	1	0.71108	1	0.056169	1	0.98198	1	NA	NA	0.27313	1
NAP1L4	6 (4%)	153	0.33182	1	0.33477	1	0.84131	1	0.67336	1	0.98866	1	0.54297	1	NA	NA	0.66684	1
CLCC1	9 (6%)	150	0.071662	1	0.96864	1	0.48048	1	1	1	0.97999	1	0.53014	1	NA	NA	0.45713	1
OR52J3	10 (6%)	149	0.10467	1	0.44961	1	0.33825	1	1	1	0.97478	1	0.79504	1	NA	NA	0.93619	1
TMCO5A	6 (4%)	153	0.3577	1	0.28673	1	0.38864	1	0.41024	1	0.99209	1	0.96628	1	NA	NA	0.2607	1
C4ORF22	8 (5%)	151	0.73706	1	0.55102	1	0.27566	1	0.71108	1	0.98462	1	0.98413	1	NA	NA	0.63289	1
MAP2K1	8 (5%)	151	0.52335	1	0.29102	1	0.1525	1	0.47695	1	0.093949	1	0.010844	1	NA	NA	0.7488	1
OR7D2	14 (9%)	145	0.77455	1	0.34768	1	0.92505	1	0.25305	1	0.94829	1	0.76496	1	NA	NA	0.12758	1
CXCR2	9 (6%)	150	0.045541	1	0.44679	1	0.32967	1	0.73021	1	0.97478	1	0.78334	1	NA	NA	0.20154	1
RBM22	4 (3%)	155	0.7192	1	0.32472	1	0.59334	1	0.298	1	0.99492	1	0.97154	1	NA	NA	0.78577	1
CX3CL1	3 (2%)	156	0.44196	1	0.94043	1	0.46225	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
IGF2BP3	3 (2%)	156	0.84813	1	0.68475	1	0.46225	1	1	1	NA	NA	NA	NA	NA	NA	NA	NA
KLRC3	4 (3%)	155	0.48224	1	0.68577	1	0.7727	1	0.63292	1	0.99492	1	0.30214	1	NA	NA	0.85189	1
LRRIQ4	15 (9%)	144	0.26619	1	0.089191	1	0.80345	1	0.57697	1	0.93181	1	0.79984	1	NA	NA	0.67787	1
NR1H4	9 (6%)	150	0.41718	1	0.28938	1	1	1	0.48482	1	0.97999	1	0.30707	1	NA	NA	0.57946	1
OR4A15	14 (9%)	145	0.78106	1	0.045343	1	0.2413	1	0.082085	1	0.96264	1	0.23937	1	NA	NA	0.51561	1
MAGEA4	8 (5%)	151	0.54932	1	0.80818	1	0.099259	1	0.71108	1	0.056169	1	0.77429	1	NA	NA	0.79796	1
DGAT2L6	8 (5%)	151	0.43619	1	0.4465	1	0.030731	1	1	1	0.97999	1	0.59784	1	NA	NA	0.72734	1
RGS18	7 (4%)	152	0.81262	1	0.33757	1	0.37994	1	0.045373	1	0.98866	1	0.80213	1	NA	NA	0.79287	1
TSGA13	6 (4%)	153	0.25669	1	0.88494	1	0.84131	1	0.41024	1	0.99209	1	0.89833	1	NA	NA	0.26603	1
OPN5	5 (3%)	154	0.28692	1	0.6497	1	0.41055	1	0.65068	1	0.99492	1	0.86888	1	NA	NA	0.75374	1
SPINK13	5 (3%)	154	0.058465	1	0.29002	1	1	1	0.65068	1	0.99209	1	0.07299	1	NA	NA	0.87123	1
