PARADIGM pathway analysis of mRNASeq expression data
Kidney Renal Clear Cell Carcinoma (Primary solid tumor)
21 April 2013  |  analyses__2013_04_21
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2013): Kidney Renal Clear Cell Carcinoma (Primary solid tumor cohort) - 21 April 2013: PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1ZS2TF6
- Overview
+ Introduction
- Summary

There were 46 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
HIF-1-alpha transcription factor network 185
Nephrin/Neph1 signaling in the kidney podocyte 165
TCR signaling in naïve CD8+ T cells 134
TCGA08_p53 132
TCGA08_retinoblastoma 118
FOXA2 and FOXA3 transcription factor networks 114
Aurora B signaling 111
Syndecan-4-mediated signaling events 110
IL12-mediated signaling events 105
FOXM1 transcription factor network 99
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data