Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.021 0.126 0.384 17.0 -9999.0 0.0 17.0 KIRREL -0.016 0.138 -9999.0 0.0 -0.48 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.021 0.126 -9999.0 0.0 -0.385 17.0 17.0 PLCG1 0.016 0.012 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.022 0.009 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.025 0.004 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.031 0.108 -9999.0 0.0 -0.284 18.0 18.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.001 0.084 -9999.0 0.0 -0.267 16.0 16.0 FYN -0.018 0.101 0.24 6.0 -0.268 19.0 25.0 mol:Ca2+ 0.014 0.094 -9999.0 0.0 -0.297 12.0 12.0 mol:DAG 0.015 0.094 -9999.0 0.0 -0.298 12.0 12.0 NPHS2 0.002 0.045 -9999.0 0.0 -0.184 7.0 7.0 mol:IP3 0.015 0.094 -9999.0 0.0 -0.298 12.0 12.0 regulation of endocytosis 0.014 0.096 -9999.0 0.0 -0.249 19.0 19.0 Nephrin/NEPH1/podocin/Cholesterol 0.015 0.103 -9999.0 0.0 -0.269 20.0 20.0 establishment of cell polarity -0.021 0.126 -9999.0 0.0 -0.384 17.0 17.0 Nephrin/NEPH1/podocin/NCK1-2 0.043 0.105 -9999.0 0.0 -0.268 17.0 17.0 Nephrin/NEPH1/beta Arrestin2 0.015 0.097 -9999.0 0.0 -0.252 19.0 19.0 NPHS1 -0.017 0.104 -9999.0 0.0 -0.233 27.0 27.0 Nephrin/NEPH1/podocin 0.017 0.1 -9999.0 0.0 -0.263 20.0 20.0 TJP1 0.025 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.016 0.095 -9999.0 0.0 -0.299 12.0 12.0 CD2AP 0.026 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.03 0.108 -9999.0 0.0 -0.283 18.0 18.0 GRB2 0.025 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.028 0.124 0.226 6.0 -0.345 19.0 25.0 cytoskeleton organization -0.02 0.095 -9999.0 0.0 -0.314 16.0 16.0 Nephrin/NEPH1 0.006 0.091 -9999.0 0.0 -0.27 17.0 17.0 Nephrin/NEPH1/ZO-1 0.018 0.107 -9999.0 0.0 -0.306 17.0 17.0