Clustering of mRNA expression: consensus NMF
Colon/Rectal Adenocarcinoma (Primary solid tumor)
23 May 2013  |  analyses__2013_05_23
Maintainer Information
Citation Information
Maintained by Hailei Zhang (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2013): Clustering of mRNA expression: consensus NMF. Broad Institute of MIT and Harvard. doi:10.7908/C1P848XZ
- Overview
+ Introduction
- Summary

The most robust consensus NMF clustering of 222 samples using the 1500 most variable genes was identified for k = 4 clusters. We computed the clustering for k = 2 to k = 8 and used the cophenetic correlation coefficient to determine the best solution.

- Results
+ Gene expression patterns of molecular subtypes
+ Consensus and correlation matrix
+ Silhouette widths
+ Samples assignment with silhouette width
+ Marker genes of each subtype
+ Methods & Data