Clustering of mRNA expression: consensus hierarchical
Kidney Renal Clear Cell Carcinoma (Primary solid tumor)
23 May 2013
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analyses__2013_05_23
Maintainer Information
Citation Information
Maintained by Hailei Zhang
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2013):
Clustering of mRNA expression: consensus hierarchical.
Broad Institute of MIT and Harvard.
doi:10.7908/C16H4FG8
Overview
Introduction
Summary
The 1500 most variable genes were selected. Consensus average linkage hierarchical clustering of 72 samples and 1500 genes identified 3 subtypes with the stability of the clustering increasing for k = 2 to k = 8 and the average silhouette width calculation for selecting the robust clusters.
Results
Silhouette width of each sample in robust cluster
Gene expression patterns of molecular subtype
Consensus and correlation matrix
Samples assignment with silhouette width
Marker genes of each subtype
Methods & Data
Copyright © 2013
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.