Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.079 0.188 0.57 25.0 -9999.0 0.0 25.0 KIRREL -0.013 0.087 -9999.0 0.0 -0.857 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.079 0.189 -9999.0 0.0 -0.571 25.0 25.0 PLCG1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.119 0.19 -9999.0 0.0 -0.606 16.0 16.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.073 0.159 -9999.0 0.0 -0.557 7.0 7.0 FYN -0.097 0.188 -9999.0 0.0 -0.562 16.0 16.0 mol:Ca2+ -0.118 0.188 -9999.0 0.0 -0.599 16.0 16.0 mol:DAG -0.118 0.189 -9999.0 0.0 -0.603 16.0 16.0 NPHS2 -0.136 0.246 -9999.0 0.0 -0.568 51.0 51.0 mol:IP3 -0.118 0.189 -9999.0 0.0 -0.603 16.0 16.0 regulation of endocytosis -0.085 0.177 -9999.0 0.0 -0.527 16.0 16.0 Nephrin/NEPH1/podocin/Cholesterol -0.121 0.193 -9999.0 0.0 -0.613 16.0 16.0 establishment of cell polarity -0.079 0.188 -9999.0 0.0 -0.57 25.0 25.0 Nephrin/NEPH1/podocin/NCK1-2 -0.107 0.173 -9999.0 0.0 -0.559 16.0 16.0 Nephrin/NEPH1/beta Arrestin2 -0.085 0.181 -9999.0 0.0 -0.535 16.0 16.0 NPHS1 -0.08 0.236 -9999.0 0.0 -0.732 23.0 23.0 Nephrin/NEPH1/podocin -0.098 0.189 -9999.0 0.0 -0.566 16.0 16.0 TJP1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.119 0.19 -9999.0 0.0 -0.606 16.0 16.0 CD2AP 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.119 0.19 -9999.0 0.0 -0.606 16.0 16.0 GRB2 0.012 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.092 0.186 -9999.0 0.0 -0.562 16.0 16.0 cytoskeleton organization -0.086 0.193 -9999.0 0.0 -0.63 9.0 9.0 Nephrin/NEPH1 -0.057 0.142 -9999.0 0.0 -0.503 16.0 16.0 Nephrin/NEPH1/ZO-1 -0.062 0.155 -9999.0 0.0 -0.574 14.0 14.0