Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.012 0.095 0.254 22.0 -9999.0 0.0 22.0 KIRREL 0.003 0.047 -9999.0 0.0 -0.292 2.0 2.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.012 0.095 -9999.0 0.0 -0.254 22.0 22.0 PLCG1 0.024 0.01 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.021 0.135 -9999.0 0.0 -0.225 58.0 58.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.044 0.11 -9999.0 0.0 -0.221 54.0 54.0 FYN -0.045 0.122 0.222 10.0 -0.215 58.0 68.0 mol:Ca2+ -0.021 0.125 -9999.0 0.0 -0.224 50.0 50.0 mol:DAG -0.02 0.126 -9999.0 0.0 -0.225 50.0 50.0 NPHS2 -0.082 0.181 -9999.0 0.0 -0.398 51.0 51.0 mol:IP3 -0.02 0.126 -9999.0 0.0 -0.225 50.0 50.0 regulation of endocytosis -0.027 0.117 -9999.0 0.0 -0.203 57.0 57.0 Nephrin/NEPH1/podocin/Cholesterol -0.033 0.127 -9999.0 0.0 -0.213 65.0 65.0 establishment of cell polarity -0.012 0.095 -9999.0 0.0 -0.254 22.0 22.0 Nephrin/NEPH1/podocin/NCK1-2 -0.01 0.131 -9999.0 0.0 -0.206 56.0 56.0 Nephrin/NEPH1/beta Arrestin2 -0.026 0.119 -9999.0 0.0 -0.205 57.0 57.0 NPHS1 -0.027 0.115 -9999.0 0.0 -0.341 22.0 22.0 Nephrin/NEPH1/podocin -0.031 0.122 -9999.0 0.0 -0.215 58.0 58.0 TJP1 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.02 0.127 -9999.0 0.0 -0.226 50.0 50.0 CD2AP 0.027 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.024 0.135 -9999.0 0.0 -0.226 58.0 58.0 GRB2 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.043 0.117 0.229 10.0 -0.205 55.0 65.0 cytoskeleton organization -0.059 0.122 0.213 3.0 -0.248 54.0 57.0 Nephrin/NEPH1 -0.003 0.066 -9999.0 0.0 -0.171 22.0 22.0 Nephrin/NEPH1/ZO-1 0.004 0.083 -9999.0 0.0 -0.199 22.0 22.0