CHASM (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Kidney Renal Clear Cell Carcinoma (Primary solid tumor)
23 September 2013
|
analyses__2013_09_23
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2013):
CHASM (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C1R20ZR1
Overview
Introduction
Summary
There are 18427 mutations identified by MuTect and 1537 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-A3-3308-01A-01D-0966-08 | NM_030964.3_R48W | 0.21 | 0 | 0.05 |
| TCGA-A3-3311-01A-01D-0966-08 | NM_033225.5_G41V | 0.27 | 0.001 | 0.05 |
| TCGA-A3-3316-01A-01D-0966-08 | NM_000314.4_S170N | 0.01 | 0 | 0.05 |
| TCGA-A3-3317-01A-01D-0966-08 | NM_004211.3_P776S | 0.25 | 0.001 | 0.05 |
| TCGA-A3-3322-01A-01D-0966-08 | NM_016507.2_R773H | 0.17 | 0 | 0.05 |
Methods & Data
Copyright © 2013
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.