CHASM (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Acute Myeloid Leukemia (Primary blood derived cancer - Peripheral blood)
23 September 2013
|
analyses__2013_09_23
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2013):
CHASM (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C1GH9G9T
Overview
Introduction
Summary
There are 12 mutations identified by MuTect and 2 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-AB-2863-03D-01W-0755-09 | NM_033158.4_H388Q | 0.4 | 0.022 | 0.25 |
| TCGA-AB-2894-03A-01W-0733-08 | NM_018907.2_V696A | 0.44 | 0.039 | 0.25 |
| TCGA-AB-2876-03A-01W-0732-08 | NM_017653.3_M1V | 0.5 | 0.071 | 0.3 |
| TCGA-AB-2805-03B-01W-0728-08 | NM_000209.3_R176Q | 0.67 | 0.31 | 0.55 |
| TCGA-AB-2904-03A-01W-0732-08 | NM_001099744.1_P180S | 0.67 | 0.31 | 0.55 |
Methods & Data
Copyright © 2013
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.