Association of mutation, copy number alteration, and subtype markers with pathways
Brain Lower Grade Glioma (Primary solid tumor)
Due to issues with GAF 3.0, we strongly advise caution in the use of these results.
23 September 2013
|
analyses__2013_09_23
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2013):
Association of mutation, copy number alteration, and subtype markers with pathways.
Broad Institute of MIT and Harvard.
doi:10.7908/C1NK3CCF
Overview
Introduction
Summary
There are 19 genes with significant mutation (Q value <= 0.1) and 497 genes with significant copy number alteration (Q value <= 0.25). The identified marker genes (Q value <= 0.01 or within top 2000) are 713 for subtype 1, 713 for subtype 2, 713 for subtype 3. Pathways significantly enriched with these genes (Q value <= 0.01) are identified :
12 pathways significantly enriched with genes with copy number alteration or mutation.
0 pathways significantly enriched with marker genes of gene expression subtype 1
0 pathways significantly enriched with marker genes of gene expression subtype 2
0 pathways significantly enriched with marker genes of gene expression subtype 3
Results
The top five pathways enriched with genes with copy number alteration or mutation
The top five pathways enriched with marker genes of gene expression subtype 1
The top five pathways enriched with marker genes of gene expression subtype 2
The top five pathways enriched with marker genes of gene expression subtype 3
Methods & Data
Copyright © 2013
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.