Clustering of mRNAseq gene expression: consensus hierarchical
Lung Squamous Cell Carcinoma (Primary solid tumor)
23 September 2013
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analyses__2013_09_23
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team
(Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2013):
Clustering of mRNAseq gene expression: consensus hierarchical.
Broad Institute of MIT and Harvard.
doi:10.7908/C1QV3JV5
Overview
Introduction
Summary
The 1500 most variable genes were selected. Consensus average linkage hierarchical clustering of 482 samples and 1500 genes identified 3 subtypes with the stability of the clustering increasing for k = 2 to k = 8 and the average silhouette width calculation for selecting the robust clusters.
Results
Gene expression patterns of molecular subtypes
Consensus and correlation matrix
Silhouette widths
Samples assignment with silhouette width
Marker genes of each subtype
Methods & Data
Copyright © 2013
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.