Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.056 0.146 0.438 25.0 -9999.0 0.0 25.0 KIRREL -0.048 0.18 -9999.0 0.0 -0.595 19.0 19.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.056 0.147 -9999.0 0.0 -0.438 25.0 25.0 PLCG1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.042 0.107 -9999.0 0.0 -0.321 8.0 8.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.008 0.093 -9999.0 0.0 -9999.0 0.0 0.0 FYN -0.024 0.107 -9999.0 0.0 -0.296 26.0 26.0 mol:Ca2+ -0.042 0.107 -9999.0 0.0 -9999.0 0.0 0.0 mol:DAG -0.042 0.107 -9999.0 0.0 -9999.0 0.0 0.0 NPHS2 -0.007 0.047 -9999.0 0.0 -0.602 1.0 1.0 mol:IP3 -0.042 0.107 -9999.0 0.0 -9999.0 0.0 0.0 regulation of endocytosis -0.017 0.1 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/Cholesterol -0.043 0.11 -9999.0 0.0 -0.324 26.0 26.0 establishment of cell polarity -0.056 0.146 -9999.0 0.0 -0.438 25.0 25.0 Nephrin/NEPH1/podocin/NCK1-2 -0.038 0.096 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/beta Arrestin2 -0.015 0.102 -9999.0 0.0 -9999.0 0.0 0.0 NPHS1 -0.017 0.106 -9999.0 0.0 -0.602 6.0 6.0 Nephrin/NEPH1/podocin -0.03 0.105 -9999.0 0.0 -0.297 26.0 26.0 TJP1 0.009 0.044 -9999.0 0.0 -0.608 1.0 1.0 NCK1 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.042 0.107 -9999.0 0.0 -9999.0 0.0 0.0 CD2AP 0.012 0.001 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.042 0.107 -9999.0 0.0 -0.316 26.0 26.0 GRB2 0.013 0.0 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.078 0.182 -9999.0 0.0 -0.402 37.0 37.0 cytoskeleton organization -0.007 0.108 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1 -0.04 0.104 -9999.0 0.0 -0.312 25.0 25.0 Nephrin/NEPH1/ZO-1 -0.046 0.118 -9999.0 0.0 -0.346 26.0 26.0