Ras signaling in the CD4+ TCR pathway Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations ERK1-2/ELK1 -0.04 0.178 -9999.0 0.0 -0.459 17.0 17.0 MAP3K8 0.008 0.085 -9999.0 0.0 -0.371 9.0 9.0 FOS -0.032 0.135 -9999.0 0.0 -0.382 15.0 15.0 PRKCA 0.011 0.071 -9999.0 0.0 -0.413 5.0 5.0 PTPN7 0.012 0.05 -9999.0 0.0 -0.242 6.0 6.0 HRAS 0.025 0.027 -9999.0 0.0 -0.236 2.0 2.0 PRKCB -0.052 0.163 -9999.0 0.0 -0.412 33.0 33.0 NRAS 0.027 0.005 -9999.0 0.0 -9999.0 0.0 0.0 RAS family/GTP 0.042 0.028 -9999.0 0.0 -9999.0 0.0 0.0 MAPK3 -0.01 0.094 -9999.0 0.0 -0.34 7.0 7.0 MAP2K1 -0.065 0.203 -9999.0 0.0 -0.46 32.0 32.0 ELK1 0.02 0.022 -9999.0 0.0 -9999.0 0.0 0.0 BRAF -0.049 0.17 -9999.0 0.0 -0.426 28.0 28.0 mol:GTP -0.001 0.002 -9999.0 0.0 -0.004 31.0 31.0 MAPK1 -0.012 0.094 -9999.0 0.0 -0.378 5.0 5.0 RAF1 -0.057 0.175 -9999.0 0.0 -0.415 33.0 33.0 KRAS 0.026 0.008 -9999.0 0.0 -9999.0 0.0 0.0