CHASM (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Prostate Adenocarcinoma (Primary solid tumor)
23 September 2013
|
analyses__2013_09_23
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2013):
CHASM (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C13B5XJP
Overview
Introduction
Summary
There are 6604 mutations identified by MuTect and 478 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-CH-5737-01A-11D-1576-08 | NM_001134420.1_A563D | 0.12 | 0 | 0.05 |
| TCGA-CH-5737-01A-11D-1576-08 | NM_001134420.1_A563D | 0.12 | 0 | 0.05 |
| TCGA-CH-5737-01A-11D-1576-08 | NM_000314.4_V119F | 0.016 | 0 | 0.05 |
| TCGA-CH-5737-01A-11D-1576-08 | NM_000314.4_V119F | 0.016 | 0 | 0.05 |
| TCGA-CH-5737-01A-11D-1576-08 | NM_024652.3_E1239G | 0.19 | 0 | 0.05 |
Methods & Data
Copyright © 2013
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.