Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity 0.397 0.296 0.584 109.0 -9999.0 0.0 109.0 KIRREL -0.115 0.198 -9999.0 0.0 -0.707 15.0 15.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs -0.398 0.297 -9999.0 0.0 -0.586 109.0 109.0 PLCG1 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.022 0.011 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP -0.424 0.322 -9999.0 0.0 -0.583 120.0 120.0 ChemicalAbstracts:57-88-5 -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.351 0.266 -9999.0 0.0 -0.498 110.0 110.0 FYN -0.415 0.286 0.265 1.0 -0.552 120.0 121.0 mol:Ca2+ -0.418 0.315 -9999.0 0.0 -0.581 117.0 117.0 mol:DAG -0.42 0.318 -9999.0 0.0 -0.584 117.0 117.0 NPHS2 -0.334 0.333 -9999.0 0.0 -0.722 68.0 68.0 mol:IP3 -0.42 0.318 -9999.0 0.0 -0.584 117.0 117.0 regulation of endocytosis -0.38 0.286 -9999.0 0.0 -0.525 118.0 118.0 Nephrin/NEPH1/podocin/Cholesterol -0.43 0.315 -9999.0 0.0 -0.584 120.0 120.0 establishment of cell polarity -0.397 0.296 -9999.0 0.0 -0.584 109.0 109.0 Nephrin/NEPH1/podocin/NCK1-2 -0.396 0.307 -9999.0 0.0 -0.549 119.0 119.0 Nephrin/NEPH1/beta Arrestin2 -0.386 0.292 -9999.0 0.0 -0.534 118.0 118.0 NPHS1 -0.473 0.322 -9999.0 0.0 -0.702 106.0 106.0 Nephrin/NEPH1/podocin -0.408 0.302 -9999.0 0.0 -0.556 120.0 120.0 TJP1 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.026 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.026 0.004 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 -0.423 0.32 -9999.0 0.0 -0.588 117.0 117.0 CD2AP 0.025 0.007 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 -0.421 0.32 -9999.0 0.0 -0.588 116.0 116.0 GRB2 0.025 0.008 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.489 0.318 0.275 1.0 -0.612 128.0 129.0 cytoskeleton organization -0.434 0.322 -9999.0 0.0 -0.629 106.0 106.0 Nephrin/NEPH1 -0.295 0.229 -9999.0 0.0 -0.436 109.0 109.0 Nephrin/NEPH1/ZO-1 -0.326 0.258 -9999.0 0.0 -0.499 105.0 105.0