Nephrin/Neph1 signaling in the kidney podocyte Entity Mean Std Dev Mean of Up Perturbations Number of Up Perturbations Mean of Down Perturbations Number of Down Perturbations Number of Total Perturbations positive regulation of NF-kappaB transcription factor activity -0.002 0.112 0.365 21.0 -9999.0 0.0 21.0 KIRREL 0.023 0.027 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1Par3/Par6/Atypical PKCs 0.002 0.112 -9999.0 0.0 -0.366 21.0 21.0 PLCG1 0.027 0.007 -9999.0 0.0 -9999.0 0.0 0.0 ARRB2 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 WASL 0.028 0.005 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/CD2AP 0.028 0.093 -9999.0 0.0 -0.274 20.0 20.0 ChemicalAbstracts:57-88-5 0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/NCK1-2/N-WASP -0.002 0.076 -9999.0 0.0 -0.259 19.0 19.0 FYN -0.005 0.092 0.272 2.0 -0.256 22.0 24.0 mol:Ca2+ 0.025 0.093 -9999.0 0.0 -0.272 21.0 21.0 mol:DAG 0.026 0.094 -9999.0 0.0 -0.273 21.0 21.0 NPHS2 0.012 0.029 -9999.0 0.0 -9999.0 0.0 0.0 mol:IP3 0.026 0.094 -9999.0 0.0 -0.273 21.0 21.0 regulation of endocytosis 0.024 0.085 -9999.0 0.0 -0.246 21.0 21.0 Nephrin/NEPH1/podocin/Cholesterol 0.014 0.088 -9999.0 0.0 -0.272 21.0 21.0 establishment of cell polarity 0.002 0.112 -9999.0 0.0 -0.365 21.0 21.0 Nephrin/NEPH1/podocin/NCK1-2 0.041 0.091 -9999.0 0.0 -0.254 19.0 19.0 Nephrin/NEPH1/beta Arrestin2 0.026 0.086 -9999.0 0.0 -0.248 21.0 21.0 NPHS1 -0.03 0.147 -9999.0 0.0 -0.494 23.0 23.0 Nephrin/NEPH1/podocin 0.016 0.086 -9999.0 0.0 -0.257 22.0 22.0 TJP1 0.027 0.008 -9999.0 0.0 -9999.0 0.0 0.0 NCK1 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 NCK2 0.029 0.003 -9999.0 0.0 -9999.0 0.0 0.0 heterophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/PLCgamma1 0.027 0.095 -9999.0 0.0 -0.274 21.0 21.0 CD2AP 0.028 0.006 -9999.0 0.0 -9999.0 0.0 0.0 Nephrin/NEPH1/podocin/GRB2 0.029 0.093 -9999.0 0.0 -0.274 20.0 20.0 GRB2 0.028 0.004 -9999.0 0.0 -9999.0 0.0 0.0 homophilic cell adhesion -0.0 0.0 -9999.0 0.0 -9999.0 0.0 0.0 TRPC6 -0.014 0.093 0.174 11.0 -0.253 22.0 33.0 cytoskeleton organization -0.021 0.09 0.2 2.0 -0.328 18.0 20.0 Nephrin/NEPH1 0.007 0.079 -9999.0 0.0 -0.254 21.0 21.0 Nephrin/NEPH1/ZO-1 0.017 0.096 -9999.0 0.0 -0.293 21.0 21.0