		Clinical Features	CN_CNMF		METHLYATION_CNMF		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	27 (21%)	100	0.00066228	0.411	0.007369	1	0.14573	1	0.67056	1	0.30207	1	1	1	0.55193	1	0.2119	1
1q gain	28 (22%)	99	0.00078856	0.488	0.05996	1	0.054447	1	0.085589	1	0.38284	1	0.22198	1	0.20976	1	0.019265	1
2p gain	10 (8%)	117	0.058047	1	0.0077188	1	0.17431	1	0.079016	1	0.09474	1	0.30827	1	0.043435	1	0.1676	1
2q gain	7 (6%)	120	0.14777	1	0.1268	1	0.48402	1	0.2045	1	0.18374	1	0.51425	1	0.15092	1	0.30818	1
3p gain	12 (9%)	115	0.0095721	1	0.34711	1	0.060781	1	0.14601	1	0.16956	1	0.35605	1	0.40735	1	0.0044288	1
3q gain	11 (9%)	116	0.019552	1	0.92354	1	0.094255	1	0.37961	1	0.54176	1	0.43822	1	0.30725	1	0.0081698	1
4p gain	25 (20%)	102	0.079768	1	0.11958	1	0.46076	1	1	1	0.32012	1	0.22728	1	0.42401	1	0.54787	1
4q gain	20 (16%)	107	0.55508	1	0.50126	1	0.86337	1	1	1	0.96663	1	0.42368	1	0.68147	1	1	1
5p gain	42 (33%)	85	0.0010235	0.629	0.32716	1	0.069468	1	1	1	0.15508	1	0.61674	1	0.045283	1	0.12805	1
5q gain	34 (27%)	93	0.038618	1	0.33734	1	0.28498	1	1	1	0.18698	1	0.67252	1	0.20911	1	0.7082	1
6p gain	24 (19%)	103	0.017821	1	0.00040521	0.253	0.033994	1	0.026519	1	0.037785	1	0.51145	1	0.015809	1	0.54787	1
6q gain	24 (19%)	103	0.013154	1	0.0033722	1	0.039076	1	0.016086	1	0.32721	1	0.093187	1	0.034648	1	0.19554	1
7p gain	34 (27%)	93	0.037066	1	0.33734	1	0.072697	1	0.3531	1	0.77181	1	0.6964	1	0.68766	1	1	1
7q gain	29 (23%)	98	0.063604	1	0.55538	1	0.55399	1	0.18891	1	0.51552	1	0.46463	1	0.20911	1	1	1
8p gain	27 (21%)	100	0.15837	1	0.93522	1	0.33553	1	1	1	0.35448	1	0.32952	1	0.62254	1	0.46123	1
8q gain	33 (26%)	94	0.064305	1	0.33271	1	0.038728	1	0.79014	1	0.10118	1	0.32888	1	0.47161	1	0.10921	1
9p gain	24 (19%)	103	0.18389	1	0.020301	1	0.23024	1	0.2493	1	0.14982	1	0.62617	1	0.2662	1	0.44052	1
9q gain	30 (24%)	97	0.037763	1	0.097807	1	0.27372	1	0.092475	1	0.26682	1	0.64848	1	0.059532	1	0.4281	1
10p gain	12 (9%)	115	0.069697	1	0.21846	1	0.7119	1	0.45901	1	0.24134	1	0.29236	1	0.29388	1	0.3315	1
10q gain	6 (5%)	121	0.48745	1	0.085866	1	0.30506	1	0.18549	1	0.2232	1	0.64042	1	0.040586	1	1	1
11p gain	8 (6%)	119	0.22992	1	0.66061	1	0.14998	1	1	1	0.18261	1	0.21828	1	0.28282	1	0.2554	1
11q gain	8 (6%)	119	0.65012	1	0.46848	1	0.22845	1	0.61581	1	0.26642	1	0.29236	1	0.6257	1	0.3315	1
12p gain	15 (12%)	112	0.60819	1	0.39557	1	0.70313	1	0.16519	1	0.040974	1	1	1	0.22813	1	0.67138	1
12q gain	9 (7%)	118	0.82934	1	0.56648	1	0.3837	1	0.79902	1	0.33149	1	1	1	0.77177	1	0.72786	1
13q gain	6 (5%)	121	0.37499	1	0.23993	1	0.11216	1	0.047468	1	0.52341	1	0.010648	1	0.098439	1	0.1548	1
14q gain	24 (19%)	103	0.18389	1	0.10528	1	0.31662	1	0.77976	1	0.4814	1	1	1	0.89507	1	0.69278	1
15q gain	32 (25%)	95	0.0041512	1	0.43604	1	0.0068072	1	0.040754	1	0.049826	1	0.029249	1	0.068315	1	0.0052937	1
16p gain	18 (14%)	109	0.022988	1	0.6269	1	0.72442	1	1	1	0.68019	1	0.2061	1	1	1	0.4704	1
16q gain	6 (5%)	121	0.073217	1	0.28052	1	0.86062	1	0.48408	1	0.82959	1	1	1	0.4912	1	0.68522	1
17p gain	26 (20%)	101	0.0013718	0.834	0.020643	1	0.51312	1	0.44418	1	0.36855	1	0.26914	1	0.25545	1	0.17831	1
17q gain	23 (18%)	104	0.073258	1	0.050061	1	0.17326	1	0.61642	1	0.46095	1	0.31887	1	1	1	0.23919	1
18p gain	20 (16%)	107	0.0083597	1	0.024046	1	0.82583	1	0.8196	1	0.39837	1	0.42368	1	0.90788	1	0.22514	1
18q gain	18 (14%)	109	0.22615	1	0.30716	1	0.67047	1	1	1	0.76269	1	0.37081	1	1	1	1	1
19p gain	36 (28%)	91	1.6545e-05	0.0105	0.13891	1	0.60645	1	0.3531	1	0.44989	1	0.51524	1	0.75713	1	0.75466	1
19q gain	26 (20%)	101	0.00040157	0.251	0.36917	1	0.81259	1	0.37861	1	0.43435	1	0.82576	1	0.19157	1	1	1
20p gain	32 (25%)	95	0.12849	1	0.19208	1	0.73156	1	0.53901	1	0.56921	1	0.69523	1	0.30625	1	0.73251	1
20q gain	40 (31%)	87	0.096403	1	0.0091397	1	1	1	0.21151	1	0.22101	1	1	1	0.098624	1	0.45052	1
21q gain	31 (24%)	96	0.0083928	1	0.0015465	0.934	0.40741	1	0.27931	1	0.19961	1	0.84955	1	0.28682	1	0.27457	1
22q gain	30 (24%)	97	0.021354	1	0.83578	1	0.4284	1	0.39155	1	0.20133	1	0.22769	1	0.13887	1	0.32151	1
xq gain	15 (12%)	112	0.0076667	1	0.063602	1	0.8274	1	1	1	0.073688	1	1	1	0.12394	1	1	1
1p loss	15 (12%)	112	0.48529	1	0.36248	1	0.050872	1	0.84946	1	0.47683	1	0.34831	1	0.74775	1	1	1
1q loss	15 (12%)	112	0.40372	1	0.24231	1	0.68321	1	0.81807	1	0.87595	1	0.69334	1	0.73297	1	0.52809	1
2p loss	39 (31%)	88	0.00051062	0.318	0.00011409	0.072	8.5262e-05	0.0539	0.00047785	0.298	0.0031299	1	0.0021662	1	0.0052297	1	0.00011887	0.0749
2q loss	31 (24%)	96	0.051562	1	0.31467	1	0.68435	1	0.72116	1	0.7124	1	0.46874	1	0.82863	1	0.10921	1
3p loss	25 (20%)	102	0.011296	1	0.0049591	1	0.0052913	1	0.0030825	1	0.044711	1	0.008384	1	0.0042029	1	0.0027279	1
3q loss	30 (24%)	97	0.027277	1	0.0027633	1	0.010267	1	0.0025156	1	0.13069	1	0.0064184	1	0.0099336	1	0.0019967	1
4p loss	21 (17%)	106	0.021918	1	0.0029373	1	0.13231	1	0.38723	1	0.15927	1	0.58913	1	0.89507	1	0.61795	1
4q loss	22 (17%)	105	0.010938	1	0.0011587	0.709	0.077929	1	0.85472	1	0.26391	1	0.82576	1	1	1	1	1
5p loss	12 (9%)	115	0.86017	1	0.23619	1	0.20687	1	0.33162	1	0.86452	1	0.3123	1	0.52946	1	0.18866	1
5q loss	15 (12%)	112	0.26898	1	0.27373	1	0.046534	1	0.26954	1	1	1	0.36569	1	0.58909	1	0.38758	1
6p loss	27 (21%)	100	0.407	1	0.014709	1	0.079917	1	0.0516	1	0.084344	1	0.32952	1	0.1232	1	0.46123	1
6q loss	17 (13%)	110	0.069226	1	0.0062581	1	0.041064	1	0.17539	1	0.053565	1	0.29877	1	0.28232	1	0.24951	1
7p loss	20 (16%)	107	0.28926	1	0.03612	1	0.11874	1	0.38678	1	0.48609	1	1	1	0.87767	1	0.19522	1
7q loss	19 (15%)	108	0.29193	1	0.18353	1	0.11874	1	0.38678	1	0.84562	1	1	1	0.6415	1	0.19522	1
8p loss	26 (20%)	101	0.8184	1	0.15672	1	0.24523	1	0.35655	1	0.23082	1	0.0063359	1	0.55147	1	0.30924	1
8q loss	16 (13%)	111	0.21868	1	0.58723	1	0.54861	1	0.41795	1	0.77965	1	0.11497	1	0.58909	1	0.38758	1
9p loss	39 (31%)	88	0.097459	1	0.32736	1	0.87615	1	0.098379	1	0.12707	1	0.25522	1	0.095353	1	0.23781	1
9q loss	26 (20%)	101	0.35107	1	0.17378	1	0.43245	1	0.37861	1	0.14879	1	0.5512	1	0.11801	1	0.17831	1
10p loss	56 (44%)	71	0.0014594	0.886	0.00017065	0.107	0.00025656	0.161	0.023382	1	0.05265	1	0.089808	1	0.22452	1	0.1069	1
10q loss	66 (52%)	61	6.9747e-08	4.46e-05	4.8223e-07	0.000307	3.0254e-07	0.000193	3.5186e-05	0.0223	0.0027714	1	0.0023057	1	0.001227	0.748	0.00054304	0.337
11p loss	45 (35%)	82	0.00079606	0.492	0.0039289	1	0.54901	1	0.14361	1	0.82088	1	0.21067	1	0.37765	1	0.18442	1
11q loss	39 (31%)	88	0.0010527	0.646	0.0081521	1	0.63154	1	0.064812	1	0.1864	1	0.055973	1	0.036642	1	0.044616	1
12p loss	28 (22%)	99	0.053952	1	0.0070304	1	0.82808	1	0.82112	1	0.57103	1	0.312	1	0.74201	1	0.57937	1
12q loss	27 (21%)	100	0.0060996	1	0.007369	1	1	1	0.67836	1	0.96889	1	0.35584	1	0.66733	1	0.59234	1
13q loss	65 (51%)	62	0.00041999	0.262	0.0018624	1	0.66	1	0.16735	1	0.78	1	0.86991	1	0.79095	1	1	1
14q loss	37 (29%)	90	0.45618	1	0.68871	1	0.0068279	1	0.36668	1	0.18465	1	0.88553	1	0.528	1	0.40869	1
15q loss	20 (16%)	107	0.080129	1	0.038594	1	0.019928	1	0.066788	1	0.014874	1	0.062546	1	0.06656	1	0.094394	1
16p loss	35 (28%)	92	0.0078815	1	0.00081566	0.503	0.70936	1	0.53089	1	0.28322	1	1	1	0.76226	1	0.30547	1
16q loss	64 (50%)	63	1.8687e-05	0.0118	3.351e-06	0.00213	0.00096129	0.592	0.0015255	0.923	0.00021247	0.133	0.0042674	1	0.0065119	1	0.001097	0.672
17p loss	25 (20%)	102	0.16256	1	0.31884	1	0.31675	1	0.73198	1	0.4381	1	0.61998	1	0.30263	1	0.42568	1
17q loss	23 (18%)	104	0.0011945	0.73	0.25805	1	0.0042746	1	0.11015	1	0.089025	1	0.095646	1	0.18451	1	0.037132	1
18p loss	30 (24%)	97	0.25695	1	0.046419	1	0.40819	1	0.72116	1	0.8913	1	1	1	0.9514	1	1	1
18q loss	32 (25%)	95	0.013335	1	0.013437	1	0.83483	1	0.59875	1	0.77484	1	0.84225	1	0.64233	1	0.83339	1
19p loss	9 (7%)	118	0.042676	1	0.056811	1	0.48402	1	1	1	0.94125	1	0.75439	1	1	1	1	1
19q loss	17 (13%)	110	0.17259	1	0.0084128	1	0.93922	1	0.76032	1	0.84562	1	0.65318	1	0.6415	1	0.71258	1
20p loss	22 (17%)	105	0.34395	1	0.24071	1	0.23436	1	0.85782	1	0.72797	1	0.27209	1	0.82098	1	0.68322	1
20q loss	10 (8%)	117	0.027883	1	0.77229	1	0.27466	1	0.65347	1	0.41981	1	0.042712	1	0.77177	1	0.30818	1
21q loss	24 (19%)	103	0.073017	1	0.17348	1	0.37146	1	0.37861	1	0.065903	1	0.093533	1	0.41559	1	0.38611	1
22q loss	38 (30%)	89	0.014507	1	0.0014629	0.887	0.033339	1	0.22667	1	0.72362	1	0.8655	1	0.74658	1	0.73607	1
xq loss	48 (38%)	79	0.032127	1	2.9545e-07	0.000189	0.05473	1	0.0013631	0.83	0.32455	1	0.25122	1	0.11546	1	0.078333	1
