CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Thyroid Adenocarcinoma (Primary solid tumor)
15 January 2014  |  analyses__2014_01_15
Maintainer Information
Citation Information
doi:10.7908/C1ST7NBG
Maintained by Spring Yingchun Liu (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2014): CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations). Broad Institute of MIT and Harvard. doi:10.7908/C1ST7NBG
- Overview
+ Introduction
- Summary

There are 4376 mutations identified by MuTect and 818 mutations with significant functional impact at BHFDR <= 0.25.

- Results
- Top Mutations

Table 1.  Get Full Table Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.

MutationID Mutation CHASM PValue BHFDR
TCGA-BJ-A0YZ-01A-11D-A10S-08 ENST00000396636_C532S 0.26 0.001 0.05
TCGA-BJ-A0Z0-01A-11D-A10S-08 NM_005921.1_L1354V 0.28 0.003 0.05
TCGA-BJ-A0Z2-01A-11D-A10S-08 NM_005343.2_Q61R 0.22 0.001 0.05
TCGA-BJ-A0Z2-01A-11D-A10S-08 NM_002742.2_F781L 0.17 0 0.05
TCGA-BJ-A0Z2-01A-11D-A10S-08 NM_004103.3_G491D 0.22 0.001 0.05
+ Methods & Data
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