CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Breast Invasive Carcinoma (Primary solid tumor)
16 April 2014
|
analyses__2014_04_16
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C1JH3JS8
Overview
Introduction
Summary
There are 49047 mutations identified by MuTect and 3933 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-A1-A0SI-01A-11D-A142-09 | NM_006218.2_H1047R | 0.016 | 0 | 0.05 |
| TCGA-A1-A0SI-01A-11D-A142-09 | NM_001126112.1_R175H | 0.02 | 0 | 0.05 |
| TCGA-A1-A0SK-01A-12D-A099-09 | NM_001126112.1_M133K | 0.008 | 0 | 0.05 |
| TCGA-A1-A0SN-01A-11D-A142-09 | NM_000906.3_N652I | 0.25 | 0.001 | 0.05 |
| TCGA-A2-A04N-01A-11D-A10Y-09 | NM_005921.1_N1374S | 0.12 | 0 | 0.05 |
Methods & Data
Copyright © 2014
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.