CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (Primary solid tumor)
16 April 2014
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analyses__2014_04_16
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C1H993SS
Overview
Introduction
Summary
There are 10988 mutations identified by MuTect and 218 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-FU-A23K-01A-11D-A16O-08 | NM_006218.2_V344G | 0.054 | 0 | 0.05 |
| TCGA-FU-A23K-01A-11D-A16O-08 | NM_006218.2_V344G | 0.054 | 0 | 0.05 |
| TCGA-C5-A1BI-01B-11D-A13W-08 | NM_006218.2_E545K | 0.068 | 0 | 0.1 |
| TCGA-C5-A1BI-01B-11D-A13W-08 | NM_006218.2_E545K | 0.068 | 0 | 0.1 |
| TCGA-C5-A1BL-01A-11D-A13W-08 | NM_182760.3_P245R | 0.068 | 0 | 0.1 |
Methods & Data
Copyright © 2014
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.