This pipeline computes the correlation between significant copy number variation (cnv focal) genes and molecular subtypes.
Testing the association between copy number variation 67 focal events and 12 molecular subtypes across 427 patients, 218 significant findings detected with P value < 0.05 and Q value < 0.25.
-
amp_2q33.1 cnv correlated to 'CN_CNMF'.
-
amp_6p21.1 cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
-
amp_8p11.23 cnv correlated to 'CN_CNMF'.
-
amp_8p11.21 cnv correlated to 'CN_CNMF'.
-
amp_8q12.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
amp_8q24.21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
-
amp_11p15.5 cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
amp_13q12.13 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
amp_13q22.1 cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
amp_16p11.2 cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
amp_16q12.1 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
amp_17q12 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
-
amp_17q24.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
-
amp_19p13.2 cnv correlated to 'CN_CNMF'.
-
amp_19q13.11 cnv correlated to 'CN_CNMF'.
-
amp_20p11.23 cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
-
amp_20q11.21 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
amp_20q12 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
amp_20q13.32 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_1p36.11 cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_1p33 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
-
del_1p13.1 cnv correlated to 'CN_CNMF'.
-
del_1q43 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
-
del_3p26.1 cnv correlated to 'CN_CNMF'.
-
del_3q26.31 cnv correlated to 'CN_CNMF'.
-
del_4p16.2 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_4q22.1 cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_4q35.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_5q11.2 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_5q21.3 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
-
del_5q23.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
-
del_8p23.3 cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_8p22 cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_8p11.21 cnv correlated to 'CN_CNMF'.
-
del_10p15.3 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
-
del_10q21.1 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
-
del_10q23.31 cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
-
del_10q25.2 cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_12p13.2 cnv correlated to 'CN_CNMF'.
-
del_14q32.11 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_15q11.2 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_15q21.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_15q22.33 cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_17p12 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_18p11.31 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_18q12.2 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_18q21.2 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_18q22.1 cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_20p12.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
-
del_21q11.2 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
del_22q13.32 cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 67 focal events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 218 significant findings detected.
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Chi-square test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
amp 20q11 21 | 306 (72%) | 121 |
7.72e-10 (5.55e-07) |
1.47e-11 (1.09e-08) |
4.38e-39 (3.49e-36) |
2.13e-12 (1.59e-09) |
0.000753 (0.426) |
0.000114 (0.0709) |
2.93e-23 (2.31e-20) |
2.01e-21 (1.56e-18) |
0.809 (1.00) |
0.000105 (0.0661) |
2.36e-12 (1.76e-09) |
0.146 (1.00) |
amp 20q12 | 307 (72%) | 120 |
8.9e-11 (6.51e-08) |
7.64e-12 (5.68e-09) |
2.02e-40 (1.61e-37) |
1.84e-11 (1.35e-08) |
0.000527 (0.303) |
2.33e-05 (0.0152) |
2.3e-22 (1.81e-19) |
6.78e-21 (5.27e-18) |
0.764 (1.00) |
0.000127 (0.0783) |
2.32e-13 (1.75e-10) |
0.14 (1.00) |
amp 20q13 32 | 310 (73%) | 117 |
1.49e-09 (1.07e-06) |
4.32e-12 (3.22e-09) |
6.54e-41 (5.23e-38) |
1.84e-11 (1.35e-08) |
0.0006 (0.344) |
1.41e-05 (0.00928) |
4.87e-22 (3.8e-19) |
7.33e-21 (5.68e-18) |
0.78 (1.00) |
0.000275 (0.164) |
7.98e-13 (5.98e-10) |
0.163 (1.00) |
del 14q32 11 | 140 (33%) | 287 |
1.11e-06 (0.000759) |
3.13e-05 (0.0202) |
4.19e-25 (3.32e-22) |
0.000117 (0.0729) |
0.000837 (0.47) |
0.0118 (1.00) |
4.38e-07 (0.000303) |
1.85e-07 (0.000129) |
0.197 (1.00) |
0.000245 (0.147) |
2.17e-05 (0.0142) |
0.166 (1.00) |
del 17p12 | 237 (56%) | 190 |
2.85e-08 (2.01e-05) |
5.25e-07 (0.000362) |
2.19e-34 (1.74e-31) |
1.25e-11 (9.25e-09) |
0.0125 (1.00) |
0.000163 (0.0989) |
9.24e-19 (7.11e-16) |
1.67e-14 (1.27e-11) |
0.659 (1.00) |
0.0359 (1.00) |
2.38e-11 (1.74e-08) |
0.0343 (1.00) |
del 18q21 2 | 269 (63%) | 158 |
5.08e-11 (3.72e-08) |
1.75e-10 (1.27e-07) |
2.05e-44 (1.65e-41) |
6.96e-14 (5.26e-11) |
0.00103 (0.567) |
0.000238 (0.143) |
3.1e-19 (2.39e-16) |
2.42e-19 (1.87e-16) |
0.449 (1.00) |
0.0692 (1.00) |
1.51e-13 (1.14e-10) |
0.0668 (1.00) |
del 18q22 1 | 269 (63%) | 158 |
1.3e-10 (9.46e-08) |
9.95e-10 (7.14e-07) |
1.41e-46 (1.13e-43) |
4.09e-14 (3.11e-11) |
0.00246 (1.00) |
0.000233 (0.14) |
4.58e-18 (3.52e-15) |
8.21e-19 (6.33e-16) |
0.574 (1.00) |
0.048 (1.00) |
4.21e-14 (3.19e-11) |
0.0679 (1.00) |
amp 11p15 5 | 89 (21%) | 338 |
4.77e-05 (0.0304) |
0.0015 (0.809) |
9.23e-06 (0.00614) |
1.74e-05 (0.0114) |
0.00106 (0.584) |
0.00596 (1.00) |
7.55e-05 (0.0478) |
1.06e-05 (0.00699) |
0.108 (1.00) |
6.72e-05 (0.0426) |
0.00198 (1.00) |
1.09e-05 (0.00721) |
amp 13q12 13 | 261 (61%) | 166 |
1.84e-06 (0.00125) |
2.26e-06 (0.00152) |
3.88e-38 (3.1e-35) |
6.56e-06 (0.00438) |
0.00498 (1.00) |
0.0126 (1.00) |
2.51e-13 (1.89e-10) |
9.29e-12 (6.9e-09) |
0.563 (1.00) |
0.0174 (1.00) |
1.23e-07 (8.64e-05) |
0.868 (1.00) |
amp 16q12 1 | 105 (25%) | 322 |
4.76e-05 (0.0303) |
2.8e-05 (0.0181) |
7.95e-21 (6.16e-18) |
0.0387 (1.00) |
0.11 (1.00) |
0.0974 (1.00) |
3.72e-05 (0.0238) |
1.59e-05 (0.0105) |
0.977 (1.00) |
0.000121 (0.0752) |
0.000106 (0.0665) |
0.287 (1.00) |
del 8p22 | 190 (44%) | 237 |
0.0027 (1.00) |
0.000179 (0.108) |
5.76e-28 (4.57e-25) |
3.92e-08 (2.76e-05) |
0.00809 (1.00) |
0.000135 (0.0832) |
2.22e-08 (1.57e-05) |
4.66e-09 (3.32e-06) |
0.476 (1.00) |
0.296 (1.00) |
3.42e-07 (0.000237) |
0.383 (1.00) |
del 15q22 33 | 153 (36%) | 274 |
0.00016 (0.0973) |
0.0005 (0.289) |
2.5e-22 (1.96e-19) |
2.99e-05 (0.0193) |
0.0438 (1.00) |
0.0409 (1.00) |
4.13e-08 (2.91e-05) |
6.26e-10 (4.52e-07) |
0.66 (1.00) |
0.000102 (0.064) |
3.2e-05 (0.0206) |
0.29 (1.00) |
del 18p11 31 | 230 (54%) | 197 |
1.04e-11 (7.71e-09) |
7.75e-10 (5.57e-07) |
2.64e-42 (2.11e-39) |
1.19e-15 (9.13e-13) |
0.000864 (0.485) |
0.00205 (1.00) |
4.52e-26 (3.58e-23) |
1.67e-24 (1.32e-21) |
0.837 (1.00) |
0.00498 (1.00) |
2.02e-14 (1.53e-11) |
0.0195 (1.00) |
del 18q12 2 | 256 (60%) | 171 |
1.76e-11 (1.3e-08) |
2.8e-10 (2.03e-07) |
1.23e-43 (9.87e-41) |
1.39e-17 (1.06e-14) |
0.00229 (1.00) |
0.000431 (0.253) |
1.36e-23 (1.07e-20) |
6.27e-24 (4.95e-21) |
0.945 (1.00) |
0.00271 (1.00) |
1.06e-14 (8.08e-12) |
0.104 (1.00) |
amp 13q22 1 | 264 (62%) | 163 |
0.000604 (0.345) |
4.25e-05 (0.0271) |
3.48e-34 (2.77e-31) |
8.41e-06 (0.0056) |
0.0148 (1.00) |
0.0449 (1.00) |
1.47e-11 (1.08e-08) |
1.33e-10 (9.64e-08) |
0.448 (1.00) |
0.0328 (1.00) |
4.48e-06 (0.003) |
0.973 (1.00) |
del 1p36 11 | 159 (37%) | 268 |
8.23e-05 (0.052) |
0.00178 (0.956) |
3.57e-15 (2.73e-12) |
3.19e-06 (0.00215) |
0.0227 (1.00) |
0.0455 (1.00) |
7.21e-08 (5.07e-05) |
4.94e-09 (3.51e-06) |
0.661 (1.00) |
0.0143 (1.00) |
1.81e-05 (0.0118) |
0.00668 (1.00) |
del 8p23 3 | 176 (41%) | 251 |
0.0119 (1.00) |
6.46e-05 (0.041) |
2.89e-22 (2.26e-19) |
3.4e-07 (0.000236) |
0.00457 (1.00) |
0.000991 (0.55) |
4.67e-07 (0.000323) |
3.06e-09 (2.19e-06) |
0.219 (1.00) |
0.152 (1.00) |
2.22e-07 (0.000155) |
0.325 (1.00) |
amp 16p11 2 | 119 (28%) | 308 |
0.000469 (0.273) |
0.000176 (0.106) |
1.56e-21 (1.22e-18) |
0.0156 (1.00) |
0.0306 (1.00) |
0.0388 (1.00) |
1.31e-05 (0.00861) |
1.05e-05 (0.00693) |
0.9 (1.00) |
0.00177 (0.951) |
0.000399 (0.235) |
0.462 (1.00) |
del 4q22 1 | 137 (32%) | 290 |
0.000412 (0.242) |
0.00225 (1.00) |
2.75e-14 (2.09e-11) |
0.000454 (0.266) |
0.104 (1.00) |
0.145 (1.00) |
1.05e-06 (0.000717) |
2.3e-07 (0.00016) |
0.387 (1.00) |
0.0122 (1.00) |
0.000181 (0.109) |
0.431 (1.00) |
del 4q35 1 | 145 (34%) | 282 |
0.00102 (0.567) |
0.00347 (1.00) |
3.65e-15 (2.79e-12) |
3.67e-06 (0.00247) |
0.0137 (1.00) |
0.0629 (1.00) |
4.39e-05 (0.028) |
8.19e-07 (0.000562) |
0.357 (1.00) |
0.024 (1.00) |
1.43e-06 (0.000976) |
0.672 (1.00) |
del 22q13 32 | 149 (35%) | 278 |
0.000509 (0.294) |
0.000134 (0.0824) |
8.41e-18 (6.46e-15) |
0.000457 (0.267) |
0.117 (1.00) |
0.339 (1.00) |
7.2e-07 (0.000495) |
2.76e-07 (0.000192) |
0.358 (1.00) |
0.00412 (1.00) |
3.42e-06 (0.0023) |
0.485 (1.00) |
amp 8q12 1 | 223 (52%) | 204 |
0.482 (1.00) |
0.0366 (1.00) |
8.52e-22 (6.64e-19) |
0.00215 (1.00) |
0.0106 (1.00) |
0.00158 (0.85) |
0.000295 (0.176) |
3.76e-05 (0.024) |
0.381 (1.00) |
0.487 (1.00) |
0.000262 (0.157) |
0.084 (1.00) |
amp 17q24 1 | 98 (23%) | 329 |
0.0177 (1.00) |
0.017 (1.00) |
1.18e-10 (8.62e-08) |
0.000351 (0.208) |
0.0619 (1.00) |
0.00786 (1.00) |
2.23e-05 (0.0146) |
0.00036 (0.213) |
0.0118 (1.00) |
0.208 (1.00) |
0.0563 (1.00) |
0.141 (1.00) |
amp 20p11 23 | 209 (49%) | 218 |
0.0777 (1.00) |
0.000396 (0.234) |
2.68e-10 (1.94e-07) |
0.0746 (1.00) |
0.00634 (1.00) |
0.182 (1.00) |
1.09e-06 (0.000744) |
0.000341 (0.202) |
0.412 (1.00) |
0.0728 (1.00) |
0.00207 (1.00) |
0.972 (1.00) |
del 4p16 2 | 128 (30%) | 299 |
0.000778 (0.44) |
0.00394 (1.00) |
6.15e-14 (4.66e-11) |
0.00133 (0.724) |
0.0264 (1.00) |
0.031 (1.00) |
5.77e-06 (0.00386) |
2.82e-08 (2e-05) |
0.357 (1.00) |
0.0225 (1.00) |
0.000138 (0.0847) |
0.465 (1.00) |
del 5q11 2 | 97 (23%) | 330 |
0.00128 (0.699) |
0.00131 (0.714) |
2.32e-10 (1.68e-07) |
0.0104 (1.00) |
0.000821 (0.462) |
0.00248 (1.00) |
0.000151 (0.0918) |
1.27e-06 (0.000865) |
0.71 (1.00) |
0.31 (1.00) |
9.16e-05 (0.0577) |
0.415 (1.00) |
del 15q11 2 | 166 (39%) | 261 |
0.000483 (0.28) |
0.00169 (0.911) |
3.99e-22 (3.12e-19) |
0.00207 (1.00) |
0.0215 (1.00) |
0.0443 (1.00) |
2.65e-07 (0.000184) |
4.27e-09 (3.04e-06) |
0.984 (1.00) |
0.0019 (1.00) |
2.84e-05 (0.0183) |
0.747 (1.00) |
del 15q21 1 | 158 (37%) | 269 |
0.0191 (1.00) |
0.00823 (1.00) |
5.66e-19 (4.37e-16) |
0.00124 (0.677) |
0.00979 (1.00) |
0.0567 (1.00) |
7.84e-08 (5.51e-05) |
4.02e-09 (2.87e-06) |
0.883 (1.00) |
0.00272 (1.00) |
0.000132 (0.0814) |
0.845 (1.00) |
del 21q11 2 | 133 (31%) | 294 |
0.0158 (1.00) |
0.0365 (1.00) |
2.16e-09 (1.55e-06) |
0.036 (1.00) |
0.161 (1.00) |
0.43 (1.00) |
0.000161 (0.098) |
7.89e-05 (0.0498) |
0.927 (1.00) |
0.174 (1.00) |
0.000102 (0.0643) |
0.181 (1.00) |
amp 6p21 1 | 92 (22%) | 335 |
0.265 (1.00) |
0.000142 (0.0868) |
5.96e-12 (4.45e-09) |
0.0259 (1.00) |
0.504 (1.00) |
0.18 (1.00) |
0.00887 (1.00) |
0.000106 (0.0665) |
0.705 (1.00) |
0.122 (1.00) |
0.000811 (0.457) |
0.606 (1.00) |
amp 8q24 21 | 247 (58%) | 180 |
0.55 (1.00) |
0.068 (1.00) |
9.9e-23 (7.78e-20) |
0.000189 (0.114) |
0.0381 (1.00) |
0.0144 (1.00) |
0.00104 (0.575) |
2.5e-05 (0.0163) |
0.702 (1.00) |
0.324 (1.00) |
0.00065 (0.37) |
0.0652 (1.00) |
del 1p33 | 115 (27%) | 312 |
0.0159 (1.00) |
0.307 (1.00) |
4.34e-13 (3.26e-10) |
0.000128 (0.0792) |
0.823 (1.00) |
0.452 (1.00) |
0.00046 (0.268) |
3.39e-05 (0.0218) |
0.71 (1.00) |
0.000943 (0.526) |
0.00106 (0.585) |
0.00322 (1.00) |
del 5q23 1 | 113 (26%) | 314 |
0.0513 (1.00) |
0.0255 (1.00) |
1.31e-10 (9.55e-08) |
0.00945 (1.00) |
0.0251 (1.00) |
0.0584 (1.00) |
0.000318 (0.189) |
3.43e-05 (0.022) |
0.855 (1.00) |
0.662 (1.00) |
0.00238 (1.00) |
0.294 (1.00) |
del 10q25 2 | 101 (24%) | 326 |
0.13 (1.00) |
0.00215 (1.00) |
7.14e-10 (5.14e-07) |
0.000473 (0.275) |
0.0068 (1.00) |
0.14 (1.00) |
0.00154 (0.832) |
3.15e-06 (0.00213) |
0.956 (1.00) |
0.0991 (1.00) |
1.51e-06 (0.00103) |
0.663 (1.00) |
del 20p12 1 | 81 (19%) | 346 |
0.0529 (1.00) |
0.194 (1.00) |
1.91e-06 (0.00129) |
0.000538 (0.309) |
0.717 (1.00) |
0.292 (1.00) |
6.19e-07 (0.000426) |
4.71e-06 (0.00316) |
0.101 (1.00) |
0.0959 (1.00) |
0.00446 (1.00) |
0.2 (1.00) |
amp 17q12 | 106 (25%) | 321 |
0.0269 (1.00) |
0.0512 (1.00) |
1.52e-08 (1.08e-05) |
0.00051 (0.294) |
0.141 (1.00) |
0.00476 (1.00) |
0.000181 (0.109) |
0.00408 (1.00) |
0.0365 (1.00) |
0.165 (1.00) |
0.0425 (1.00) |
0.299 (1.00) |
del 1q43 | 51 (12%) | 376 |
0.0616 (1.00) |
0.442 (1.00) |
2.09e-06 (0.00142) |
0.015 (1.00) |
0.477 (1.00) |
0.517 (1.00) |
0.00351 (1.00) |
9.6e-06 (0.00637) |
0.146 (1.00) |
0.00809 (1.00) |
0.000953 (0.531) |
0.0343 (1.00) |
del 5q21 3 | 122 (29%) | 305 |
0.0663 (1.00) |
0.0103 (1.00) |
1.22e-11 (9.07e-09) |
0.00521 (1.00) |
0.0453 (1.00) |
0.0567 (1.00) |
0.000486 (0.282) |
0.000142 (0.0868) |
0.961 (1.00) |
0.887 (1.00) |
0.0187 (1.00) |
0.151 (1.00) |
del 10p15 3 | 75 (18%) | 352 |
0.123 (1.00) |
0.0986 (1.00) |
4.85e-07 (0.000334) |
0.00265 (1.00) |
0.0225 (1.00) |
0.0412 (1.00) |
0.0566 (1.00) |
0.000108 (0.0675) |
0.46 (1.00) |
0.000977 (0.543) |
0.00119 (0.654) |
0.32 (1.00) |
del 10q21 1 | 90 (21%) | 337 |
0.004 (1.00) |
0.00919 (1.00) |
2.13e-10 (1.55e-07) |
0.0155 (1.00) |
0.071 (1.00) |
0.116 (1.00) |
0.00194 (1.00) |
0.000404 (0.238) |
0.753 (1.00) |
0.0986 (1.00) |
0.0012 (0.658) |
0.79 (1.00) |
del 10q23 31 | 102 (24%) | 325 |
0.104 (1.00) |
0.0107 (1.00) |
1.72e-07 (0.00012) |
0.00724 (1.00) |
0.146 (1.00) |
0.24 (1.00) |
0.00719 (1.00) |
0.000938 (0.524) |
0.581 (1.00) |
0.0136 (1.00) |
0.000106 (0.0665) |
0.376 (1.00) |
amp 2q33 1 | 84 (20%) | 343 |
0.167 (1.00) |
0.0357 (1.00) |
0.00015 (0.0914) |
0.0381 (1.00) |
0.0438 (1.00) |
0.0978 (1.00) |
0.00128 (0.697) |
0.0187 (1.00) |
0.289 (1.00) |
0.123 (1.00) |
0.173 (1.00) |
0.141 (1.00) |
amp 8p11 23 | 151 (35%) | 276 |
0.297 (1.00) |
0.121 (1.00) |
2.63e-13 (1.98e-10) |
0.64 (1.00) |
0.761 (1.00) |
0.799 (1.00) |
0.0874 (1.00) |
0.0106 (1.00) |
0.362 (1.00) |
0.365 (1.00) |
0.26 (1.00) |
1 (1.00) |
amp 8p11 21 | 181 (42%) | 246 |
0.438 (1.00) |
0.0714 (1.00) |
3.94e-23 (3.1e-20) |
0.438 (1.00) |
0.176 (1.00) |
0.00818 (1.00) |
0.172 (1.00) |
0.00539 (1.00) |
0.668 (1.00) |
0.498 (1.00) |
0.221 (1.00) |
0.587 (1.00) |
amp 19p13 2 | 70 (16%) | 357 |
0.0669 (1.00) |
0.0249 (1.00) |
6.89e-06 (0.00459) |
0.0213 (1.00) |
0.67 (1.00) |
0.284 (1.00) |
0.72 (1.00) |
0.0396 (1.00) |
0.335 (1.00) |
0.0146 (1.00) |
0.0108 (1.00) |
0.274 (1.00) |
amp 19q13 11 | 88 (21%) | 339 |
0.187 (1.00) |
0.0238 (1.00) |
2.77e-05 (0.018) |
0.104 (1.00) |
0.0341 (1.00) |
0.564 (1.00) |
0.0721 (1.00) |
0.0283 (1.00) |
0.45 (1.00) |
0.0833 (1.00) |
0.0302 (1.00) |
0.221 (1.00) |
del 1p13 1 | 110 (26%) | 317 |
0.0886 (1.00) |
0.256 (1.00) |
5.97e-12 (4.45e-09) |
0.012 (1.00) |
0.678 (1.00) |
0.649 (1.00) |
0.0019 (1.00) |
0.000614 (0.35) |
0.786 (1.00) |
0.0147 (1.00) |
0.0435 (1.00) |
0.0165 (1.00) |
del 3p26 1 | 65 (15%) | 362 |
0.122 (1.00) |
0.277 (1.00) |
2.58e-05 (0.0168) |
0.109 (1.00) |
0.744 (1.00) |
0.856 (1.00) |
0.032 (1.00) |
0.0276 (1.00) |
0.826 (1.00) |
0.0883 (1.00) |
0.0014 (0.759) |
0.558 (1.00) |
del 3q26 31 | 44 (10%) | 383 |
0.708 (1.00) |
0.934 (1.00) |
0.000144 (0.0881) |
0.125 (1.00) |
0.507 (1.00) |
0.383 (1.00) |
0.0769 (1.00) |
0.154 (1.00) |
0.43 (1.00) |
0.696 (1.00) |
0.00721 (1.00) |
0.0333 (1.00) |
del 8p11 21 | 44 (10%) | 383 |
0.0261 (1.00) |
0.377 (1.00) |
1.3e-05 (0.00859) |
0.282 (1.00) |
0.0434 (1.00) |
0.0216 (1.00) |
0.105 (1.00) |
0.0142 (1.00) |
0.349 (1.00) |
0.345 (1.00) |
0.0569 (1.00) |
0.335 (1.00) |
del 12p13 2 | 54 (13%) | 373 |
0.0101 (1.00) |
0.00427 (1.00) |
6.93e-11 (5.08e-08) |
0.0215 (1.00) |
0.311 (1.00) |
0.907 (1.00) |
0.00272 (1.00) |
0.00294 (1.00) |
0.779 (1.00) |
0.267 (1.00) |
0.00496 (1.00) |
0.29 (1.00) |
amp 5p13 2 | 82 (19%) | 345 |
0.374 (1.00) |
0.273 (1.00) |
0.000666 (0.378) |
0.493 (1.00) |
0.00475 (1.00) |
0.686 (1.00) |
0.0323 (1.00) |
0.000914 (0.512) |
0.723 (1.00) |
0.107 (1.00) |
0.0657 (1.00) |
0.398 (1.00) |
amp 5q22 3 | 41 (10%) | 386 |
0.924 (1.00) |
0.804 (1.00) |
0.00735 (1.00) |
0.861 (1.00) |
0.333 (1.00) |
0.466 (1.00) |
0.324 (1.00) |
0.00367 (1.00) |
0.962 (1.00) |
0.852 (1.00) |
0.218 (1.00) |
0.446 (1.00) |
amp 12p13 33 | 105 (25%) | 322 |
0.659 (1.00) |
0.605 (1.00) |
0.104 (1.00) |
0.234 (1.00) |
0.425 (1.00) |
0.951 (1.00) |
0.954 (1.00) |
0.981 (1.00) |
0.509 (1.00) |
0.696 (1.00) |
0.678 (1.00) |
0.563 (1.00) |
del 2p21 | 16 (4%) | 411 |
0.594 (1.00) |
0.876 (1.00) |
0.656 (1.00) |
0.837 (1.00) |
0.807 (1.00) |
0.833 (1.00) |
0.609 (1.00) |
0.368 (1.00) |
0.0902 (1.00) |
0.524 (1.00) |
0.269 (1.00) |
0.791 (1.00) |
del 2q22 1 | 20 (5%) | 407 |
0.81 (1.00) |
0.388 (1.00) |
0.494 (1.00) |
0.93 (1.00) |
0.0287 (1.00) |
0.0686 (1.00) |
0.907 (1.00) |
0.844 (1.00) |
0.684 (1.00) |
0.935 (1.00) |
0.305 (1.00) |
0.803 (1.00) |
del 2q37 2 | 21 (5%) | 406 |
0.805 (1.00) |
0.0652 (1.00) |
0.449 (1.00) |
0.288 (1.00) |
0.36 (1.00) |
0.208 (1.00) |
0.991 (1.00) |
0.93 (1.00) |
0.24 (1.00) |
0.366 (1.00) |
1 (1.00) |
0.787 (1.00) |
del 3p14 2 | 80 (19%) | 347 |
0.561 (1.00) |
0.557 (1.00) |
0.0243 (1.00) |
0.389 (1.00) |
0.52 (1.00) |
0.215 (1.00) |
0.142 (1.00) |
0.00446 (1.00) |
0.647 (1.00) |
0.804 (1.00) |
0.00404 (1.00) |
0.775 (1.00) |
del 6p25 3 | 54 (13%) | 373 |
0.873 (1.00) |
0.714 (1.00) |
0.315 (1.00) |
0.0776 (1.00) |
0.0432 (1.00) |
0.86 (1.00) |
0.922 (1.00) |
0.902 (1.00) |
0.652 (1.00) |
0.512 (1.00) |
0.177 (1.00) |
0.53 (1.00) |
del 6q26 | 59 (14%) | 368 |
0.581 (1.00) |
0.359 (1.00) |
0.803 (1.00) |
0.391 (1.00) |
0.0848 (1.00) |
0.24 (1.00) |
0.0839 (1.00) |
0.47 (1.00) |
0.664 (1.00) |
0.137 (1.00) |
0.448 (1.00) |
0.354 (1.00) |
del 7q31 1 | 12 (3%) | 415 |
1 (1.00) |
0.504 (1.00) |
0.12 (1.00) |
0.66 (1.00) |
0.165 (1.00) |
0.0916 (1.00) |
0.222 (1.00) |
0.445 (1.00) |
0.759 (1.00) |
0.931 (1.00) |
0.629 (1.00) |
0.853 (1.00) |
del 9p21 3 | 57 (13%) | 370 |
0.447 (1.00) |
0.0262 (1.00) |
0.0006 (0.344) |
0.141 (1.00) |
0.814 (1.00) |
0.141 (1.00) |
0.0437 (1.00) |
0.0142 (1.00) |
0.607 (1.00) |
0.552 (1.00) |
0.0465 (1.00) |
0.666 (1.00) |
del 13q14 13 | 18 (4%) | 409 |
0.275 (1.00) |
0.876 (1.00) |
0.228 (1.00) |
0.18 (1.00) |
0.24 (1.00) |
0.34 (1.00) |
0.495 (1.00) |
1 (1.00) |
0.655 (1.00) |
0.86 (1.00) |
0.632 (1.00) |
0.787 (1.00) |
del 16p13 3 | 51 (12%) | 376 |
0.23 (1.00) |
0.364 (1.00) |
0.0771 (1.00) |
0.102 (1.00) |
0.392 (1.00) |
0.867 (1.00) |
0.236 (1.00) |
0.0309 (1.00) |
0.836 (1.00) |
0.486 (1.00) |
0.134 (1.00) |
0.422 (1.00) |
del 16q23 1 | 55 (13%) | 372 |
0.279 (1.00) |
0.00599 (1.00) |
0.0788 (1.00) |
0.583 (1.00) |
0.144 (1.00) |
0.862 (1.00) |
0.177 (1.00) |
0.178 (1.00) |
0.528 (1.00) |
0.858 (1.00) |
0.808 (1.00) |
0.773 (1.00) |
del 17q24 3 | 62 (15%) | 365 |
0.0957 (1.00) |
0.686 (1.00) |
0.00354 (1.00) |
0.0024 (1.00) |
0.831 (1.00) |
0.479 (1.00) |
0.00578 (1.00) |
0.00185 (0.989) |
0.698 (1.00) |
0.807 (1.00) |
0.0117 (1.00) |
0.201 (1.00) |
del 19p13 3 | 59 (14%) | 368 |
0.13 (1.00) |
0.0411 (1.00) |
0.000684 (0.388) |
0.287 (1.00) |
0.967 (1.00) |
0.0695 (1.00) |
0.0112 (1.00) |
0.00238 (1.00) |
0.635 (1.00) |
0.631 (1.00) |
0.0289 (1.00) |
0.272 (1.00) |
P value = 0.00015 (Fisher's exact test), Q value = 0.091
Table S1. Gene #1: 'amp_2q33.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 1(2Q33.1) MUTATED | 50 | 23 | 11 |
AMP PEAK 1(2Q33.1) WILD-TYPE | 121 | 172 | 50 |
Figure S1. Get High-res Image Gene #1: 'amp_2q33.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D1V3.png)
P value = 0.000142 (Fisher's exact test), Q value = 0.087
Table S2. Gene #4: 'amp_6p21.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 4(6P21.1) MUTATED | 7 | 3 | 19 |
AMP PEAK 4(6P21.1) WILD-TYPE | 49 | 40 | 28 |
Figure S2. Get High-res Image Gene #4: 'amp_6p21.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D4V2.png)
P value = 5.96e-12 (Fisher's exact test), Q value = 4.4e-09
Table S3. Gene #4: 'amp_6p21.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 4(6P21.1) MUTATED | 65 | 15 | 12 |
AMP PEAK 4(6P21.1) WILD-TYPE | 106 | 180 | 49 |
Figure S3. Get High-res Image Gene #4: 'amp_6p21.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D4V3.png)
P value = 0.000106 (Fisher's exact test), Q value = 0.066
Table S4. Gene #4: 'amp_6p21.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 4(6P21.1) MUTATED | 36 | 8 | 48 |
AMP PEAK 4(6P21.1) WILD-TYPE | 128 | 90 | 113 |
Figure S4. Get High-res Image Gene #4: 'amp_6p21.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D4V8.png)
P value = 2.63e-13 (Fisher's exact test), Q value = 2e-10
Table S5. Gene #5: 'amp_8p11.23' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 5(8P11.23) MUTATED | 59 | 45 | 47 |
AMP PEAK 5(8P11.23) WILD-TYPE | 112 | 150 | 14 |
Figure S5. Get High-res Image Gene #5: 'amp_8p11.23' versus Molecular Subtype #3: 'CN_CNMF'
![](D5V3.png)
P value = 3.94e-23 (Fisher's exact test), Q value = 3.1e-20
Table S6. Gene #6: 'amp_8p11.21' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 6(8P11.21) MUTATED | 74 | 49 | 58 |
AMP PEAK 6(8P11.21) WILD-TYPE | 97 | 146 | 3 |
Figure S6. Get High-res Image Gene #6: 'amp_8p11.21' versus Molecular Subtype #3: 'CN_CNMF'
![](D6V3.png)
P value = 8.52e-22 (Fisher's exact test), Q value = 6.6e-19
Table S7. Gene #7: 'amp_8q12.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 7(8Q12.1) MUTATED | 105 | 60 | 58 |
AMP PEAK 7(8Q12.1) WILD-TYPE | 66 | 135 | 3 |
Figure S7. Get High-res Image Gene #7: 'amp_8q12.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D7V3.png)
P value = 0.000295 (Chi-square test), Q value = 0.18
Table S8. Gene #7: 'amp_8q12.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 7(8Q12.1) MUTATED | 16 | 74 | 42 | 31 | 58 |
AMP PEAK 7(8Q12.1) WILD-TYPE | 17 | 39 | 29 | 59 | 58 |
Figure S8. Get High-res Image Gene #7: 'amp_8q12.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D7V7.png)
P value = 3.76e-05 (Fisher's exact test), Q value = 0.024
Table S9. Gene #7: 'amp_8q12.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 7(8Q12.1) MUTATED | 79 | 37 | 105 |
AMP PEAK 7(8Q12.1) WILD-TYPE | 85 | 61 | 56 |
Figure S9. Get High-res Image Gene #7: 'amp_8q12.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D7V8.png)
P value = 0.000262 (Fisher's exact test), Q value = 0.16
Table S10. Gene #7: 'amp_8q12.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 7(8Q12.1) MUTATED | 53 | 29 | 40 |
AMP PEAK 7(8Q12.1) WILD-TYPE | 26 | 49 | 23 |
Figure S10. Get High-res Image Gene #7: 'amp_8q12.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D7V11.png)
P value = 9.9e-23 (Fisher's exact test), Q value = 7.8e-20
Table S11. Gene #8: 'amp_8q24.21' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 8(8Q24.21) MUTATED | 117 | 70 | 60 |
AMP PEAK 8(8Q24.21) WILD-TYPE | 54 | 125 | 1 |
Figure S11. Get High-res Image Gene #8: 'amp_8q24.21' versus Molecular Subtype #3: 'CN_CNMF'
![](D8V3.png)
P value = 0.000189 (Fisher's exact test), Q value = 0.11
Table S12. Gene #8: 'amp_8q24.21' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 8(8Q24.21) MUTATED | 86 | 42 | 39 |
AMP PEAK 8(8Q24.21) WILD-TYPE | 28 | 46 | 29 |
Figure S12. Get High-res Image Gene #8: 'amp_8q24.21' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D8V4.png)
P value = 2.5e-05 (Fisher's exact test), Q value = 0.016
Table S13. Gene #8: 'amp_8q24.21' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 8(8Q24.21) MUTATED | 89 | 42 | 114 |
AMP PEAK 8(8Q24.21) WILD-TYPE | 75 | 56 | 47 |
Figure S13. Get High-res Image Gene #8: 'amp_8q24.21' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D8V8.png)
P value = 4.77e-05 (Fisher's exact test), Q value = 0.03
Table S14. Gene #9: 'amp_11p15.5' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
AMP PEAK 9(11P15.5) MUTATED | 2 | 18 | 3 | 12 |
AMP PEAK 9(11P15.5) WILD-TYPE | 33 | 43 | 26 | 9 |
Figure S14. Get High-res Image Gene #9: 'amp_11p15.5' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D9V1.png)
P value = 9.23e-06 (Fisher's exact test), Q value = 0.0061
Table S15. Gene #9: 'amp_11p15.5' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 9(11P15.5) MUTATED | 54 | 22 | 13 |
AMP PEAK 9(11P15.5) WILD-TYPE | 117 | 173 | 48 |
Figure S15. Get High-res Image Gene #9: 'amp_11p15.5' versus Molecular Subtype #3: 'CN_CNMF'
![](D9V3.png)
P value = 1.74e-05 (Fisher's exact test), Q value = 0.011
Table S16. Gene #9: 'amp_11p15.5' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 9(11P15.5) MUTATED | 35 | 5 | 11 |
AMP PEAK 9(11P15.5) WILD-TYPE | 79 | 83 | 57 |
Figure S16. Get High-res Image Gene #9: 'amp_11p15.5' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D9V4.png)
P value = 7.55e-05 (Chi-square test), Q value = 0.048
Table S17. Gene #9: 'amp_11p15.5' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 9(11P15.5) MUTATED | 6 | 33 | 15 | 3 | 31 |
AMP PEAK 9(11P15.5) WILD-TYPE | 27 | 80 | 56 | 87 | 85 |
Figure S17. Get High-res Image Gene #9: 'amp_11p15.5' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D9V7.png)
P value = 1.06e-05 (Fisher's exact test), Q value = 0.007
Table S18. Gene #9: 'amp_11p15.5' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 9(11P15.5) MUTATED | 42 | 5 | 41 |
AMP PEAK 9(11P15.5) WILD-TYPE | 122 | 93 | 120 |
Figure S18. Get High-res Image Gene #9: 'amp_11p15.5' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D9V8.png)
P value = 6.72e-05 (Fisher's exact test), Q value = 0.043
Table S19. Gene #9: 'amp_11p15.5' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 80 | 174 | 143 |
AMP PEAK 9(11P15.5) MUTATED | 4 | 46 | 34 |
AMP PEAK 9(11P15.5) WILD-TYPE | 76 | 128 | 109 |
Figure S19. Get High-res Image Gene #9: 'amp_11p15.5' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
![](D9V10.png)
P value = 1.09e-05 (Fisher's exact test), Q value = 0.0072
Table S20. Gene #9: 'amp_11p15.5' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 21 | 86 | 113 |
AMP PEAK 9(11P15.5) MUTATED | 12 | 16 | 11 |
AMP PEAK 9(11P15.5) WILD-TYPE | 9 | 70 | 102 |
Figure S20. Get High-res Image Gene #9: 'amp_11p15.5' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
![](D9V12.png)
P value = 1.84e-06 (Fisher's exact test), Q value = 0.0012
Table S21. Gene #11: 'amp_13q12.13' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
AMP PEAK 11(13Q12.13) MUTATED | 15 | 51 | 10 | 16 |
AMP PEAK 11(13Q12.13) WILD-TYPE | 20 | 10 | 19 | 5 |
Figure S21. Get High-res Image Gene #11: 'amp_13q12.13' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D11V1.png)
P value = 2.26e-06 (Fisher's exact test), Q value = 0.0015
Table S22. Gene #11: 'amp_13q12.13' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 11(13Q12.13) MUTATED | 39 | 14 | 39 |
AMP PEAK 11(13Q12.13) WILD-TYPE | 17 | 29 | 8 |
Figure S22. Get High-res Image Gene #11: 'amp_13q12.13' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D11V2.png)
P value = 3.88e-38 (Fisher's exact test), Q value = 3.1e-35
Table S23. Gene #11: 'amp_13q12.13' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 11(13Q12.13) MUTATED | 161 | 61 | 39 |
AMP PEAK 11(13Q12.13) WILD-TYPE | 10 | 134 | 22 |
Figure S23. Get High-res Image Gene #11: 'amp_13q12.13' versus Molecular Subtype #3: 'CN_CNMF'
![](D11V3.png)
P value = 6.56e-06 (Fisher's exact test), Q value = 0.0044
Table S24. Gene #11: 'amp_13q12.13' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 11(13Q12.13) MUTATED | 89 | 42 | 35 |
AMP PEAK 11(13Q12.13) WILD-TYPE | 25 | 46 | 33 |
Figure S24. Get High-res Image Gene #11: 'amp_13q12.13' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D11V4.png)
P value = 2.51e-13 (Chi-square test), Q value = 1.9e-10
Table S25. Gene #11: 'amp_13q12.13' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 11(13Q12.13) MUTATED | 24 | 88 | 41 | 24 | 82 |
AMP PEAK 11(13Q12.13) WILD-TYPE | 9 | 25 | 30 | 66 | 34 |
Figure S25. Get High-res Image Gene #11: 'amp_13q12.13' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D11V7.png)
P value = 9.29e-12 (Fisher's exact test), Q value = 6.9e-09
Table S26. Gene #11: 'amp_13q12.13' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 11(13Q12.13) MUTATED | 103 | 32 | 124 |
AMP PEAK 11(13Q12.13) WILD-TYPE | 61 | 66 | 37 |
Figure S26. Get High-res Image Gene #11: 'amp_13q12.13' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D11V8.png)
P value = 1.23e-07 (Fisher's exact test), Q value = 8.6e-05
Table S27. Gene #11: 'amp_13q12.13' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 11(13Q12.13) MUTATED | 63 | 29 | 43 |
AMP PEAK 11(13Q12.13) WILD-TYPE | 16 | 49 | 20 |
Figure S27. Get High-res Image Gene #11: 'amp_13q12.13' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D11V11.png)
P value = 4.25e-05 (Fisher's exact test), Q value = 0.027
Table S28. Gene #12: 'amp_13q22.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 12(13Q22.1) MUTATED | 39 | 15 | 37 |
AMP PEAK 12(13Q22.1) WILD-TYPE | 17 | 28 | 10 |
Figure S28. Get High-res Image Gene #12: 'amp_13q22.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D12V2.png)
P value = 3.48e-34 (Fisher's exact test), Q value = 2.8e-31
Table S29. Gene #12: 'amp_13q22.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 12(13Q22.1) MUTATED | 159 | 65 | 40 |
AMP PEAK 12(13Q22.1) WILD-TYPE | 12 | 130 | 21 |
Figure S29. Get High-res Image Gene #12: 'amp_13q22.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D12V3.png)
P value = 8.41e-06 (Fisher's exact test), Q value = 0.0056
Table S30. Gene #12: 'amp_13q22.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 12(13Q22.1) MUTATED | 90 | 44 | 35 |
AMP PEAK 12(13Q22.1) WILD-TYPE | 24 | 44 | 33 |
Figure S30. Get High-res Image Gene #12: 'amp_13q22.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D12V4.png)
P value = 1.47e-11 (Chi-square test), Q value = 1.1e-08
Table S31. Gene #12: 'amp_13q22.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 12(13Q22.1) MUTATED | 23 | 89 | 42 | 27 | 81 |
AMP PEAK 12(13Q22.1) WILD-TYPE | 10 | 24 | 29 | 63 | 35 |
Figure S31. Get High-res Image Gene #12: 'amp_13q22.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D12V7.png)
P value = 1.33e-10 (Fisher's exact test), Q value = 9.6e-08
Table S32. Gene #12: 'amp_13q22.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 12(13Q22.1) MUTATED | 102 | 35 | 125 |
AMP PEAK 12(13Q22.1) WILD-TYPE | 62 | 63 | 36 |
Figure S32. Get High-res Image Gene #12: 'amp_13q22.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D12V8.png)
P value = 4.48e-06 (Fisher's exact test), Q value = 0.003
Table S33. Gene #12: 'amp_13q22.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 12(13Q22.1) MUTATED | 63 | 33 | 43 |
AMP PEAK 12(13Q22.1) WILD-TYPE | 16 | 45 | 20 |
Figure S33. Get High-res Image Gene #12: 'amp_13q22.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D12V11.png)
P value = 0.000176 (Fisher's exact test), Q value = 0.11
Table S34. Gene #13: 'amp_16p11.2' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 13(16P11.2) MUTATED | 14 | 6 | 25 |
AMP PEAK 13(16P11.2) WILD-TYPE | 42 | 37 | 22 |
Figure S34. Get High-res Image Gene #13: 'amp_16p11.2' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D13V2.png)
P value = 1.56e-21 (Fisher's exact test), Q value = 1.2e-18
Table S35. Gene #13: 'amp_16p11.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 13(16P11.2) MUTATED | 91 | 17 | 11 |
AMP PEAK 13(16P11.2) WILD-TYPE | 80 | 178 | 50 |
Figure S35. Get High-res Image Gene #13: 'amp_16p11.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D13V3.png)
P value = 1.31e-05 (Chi-square test), Q value = 0.0086
Table S36. Gene #13: 'amp_16p11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 13(16P11.2) MUTATED | 8 | 42 | 19 | 7 | 43 |
AMP PEAK 13(16P11.2) WILD-TYPE | 25 | 71 | 52 | 83 | 73 |
Figure S36. Get High-res Image Gene #13: 'amp_16p11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D13V7.png)
P value = 1.05e-05 (Fisher's exact test), Q value = 0.0069
Table S37. Gene #13: 'amp_16p11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 13(16P11.2) MUTATED | 54 | 10 | 55 |
AMP PEAK 13(16P11.2) WILD-TYPE | 110 | 88 | 106 |
Figure S37. Get High-res Image Gene #13: 'amp_16p11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D13V8.png)
P value = 0.000399 (Fisher's exact test), Q value = 0.24
Table S38. Gene #13: 'amp_16p11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 13(16P11.2) MUTATED | 31 | 10 | 21 |
AMP PEAK 13(16P11.2) WILD-TYPE | 48 | 68 | 42 |
Figure S38. Get High-res Image Gene #13: 'amp_16p11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D13V11.png)
P value = 4.76e-05 (Fisher's exact test), Q value = 0.03
Table S39. Gene #14: 'amp_16q12.1' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
AMP PEAK 14(16Q12.1) MUTATED | 4 | 22 | 2 | 12 |
AMP PEAK 14(16Q12.1) WILD-TYPE | 31 | 39 | 27 | 9 |
Figure S39. Get High-res Image Gene #14: 'amp_16q12.1' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D14V1.png)
P value = 2.8e-05 (Fisher's exact test), Q value = 0.018
Table S40. Gene #14: 'amp_16q12.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 14(16Q12.1) MUTATED | 14 | 3 | 23 |
AMP PEAK 14(16Q12.1) WILD-TYPE | 42 | 40 | 24 |
Figure S40. Get High-res Image Gene #14: 'amp_16q12.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D14V2.png)
P value = 7.95e-21 (Fisher's exact test), Q value = 6.2e-18
Table S41. Gene #14: 'amp_16q12.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 14(16Q12.1) MUTATED | 83 | 13 | 9 |
AMP PEAK 14(16Q12.1) WILD-TYPE | 88 | 182 | 52 |
Figure S41. Get High-res Image Gene #14: 'amp_16q12.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D14V3.png)
P value = 3.72e-05 (Chi-square test), Q value = 0.024
Table S42. Gene #14: 'amp_16q12.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 14(16Q12.1) MUTATED | 8 | 37 | 17 | 5 | 38 |
AMP PEAK 14(16Q12.1) WILD-TYPE | 25 | 76 | 54 | 85 | 78 |
Figure S42. Get High-res Image Gene #14: 'amp_16q12.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D14V7.png)
P value = 1.59e-05 (Fisher's exact test), Q value = 0.01
Table S43. Gene #14: 'amp_16q12.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 14(16Q12.1) MUTATED | 47 | 8 | 50 |
AMP PEAK 14(16Q12.1) WILD-TYPE | 117 | 90 | 111 |
Figure S43. Get High-res Image Gene #14: 'amp_16q12.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D14V8.png)
P value = 0.000121 (Fisher's exact test), Q value = 0.075
Table S44. Gene #14: 'amp_16q12.1' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 80 | 174 | 143 |
AMP PEAK 14(16Q12.1) MUTATED | 7 | 46 | 47 |
AMP PEAK 14(16Q12.1) WILD-TYPE | 73 | 128 | 96 |
Figure S44. Get High-res Image Gene #14: 'amp_16q12.1' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
![](D14V10.png)
P value = 0.000106 (Fisher's exact test), Q value = 0.066
Table S45. Gene #14: 'amp_16q12.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 14(16Q12.1) MUTATED | 27 | 7 | 21 |
AMP PEAK 14(16Q12.1) WILD-TYPE | 52 | 71 | 42 |
Figure S45. Get High-res Image Gene #14: 'amp_16q12.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D14V11.png)
P value = 1.52e-08 (Fisher's exact test), Q value = 1.1e-05
Table S46. Gene #15: 'amp_17q12' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 15(17Q12) MUTATED | 65 | 23 | 18 |
AMP PEAK 15(17Q12) WILD-TYPE | 106 | 172 | 43 |
Figure S46. Get High-res Image Gene #15: 'amp_17q12' versus Molecular Subtype #3: 'CN_CNMF'
![](D15V3.png)
P value = 0.000181 (Chi-square test), Q value = 0.11
Table S47. Gene #15: 'amp_17q12' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 15(17Q12) MUTATED | 9 | 44 | 12 | 11 | 29 |
AMP PEAK 15(17Q12) WILD-TYPE | 24 | 69 | 59 | 79 | 87 |
Figure S47. Get High-res Image Gene #15: 'amp_17q12' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D15V7.png)
P value = 1.18e-10 (Fisher's exact test), Q value = 8.6e-08
Table S48. Gene #16: 'amp_17q24.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 16(17Q24.1) MUTATED | 63 | 17 | 18 |
AMP PEAK 16(17Q24.1) WILD-TYPE | 108 | 178 | 43 |
Figure S48. Get High-res Image Gene #16: 'amp_17q24.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D16V3.png)
P value = 0.000351 (Fisher's exact test), Q value = 0.21
Table S49. Gene #16: 'amp_17q24.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 16(17Q24.1) MUTATED | 41 | 16 | 8 |
AMP PEAK 16(17Q24.1) WILD-TYPE | 73 | 72 | 60 |
Figure S49. Get High-res Image Gene #16: 'amp_17q24.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D16V4.png)
P value = 2.23e-05 (Chi-square test), Q value = 0.015
Table S50. Gene #16: 'amp_17q24.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 16(17Q24.1) MUTATED | 10 | 43 | 8 | 11 | 26 |
AMP PEAK 16(17Q24.1) WILD-TYPE | 23 | 70 | 63 | 79 | 90 |
Figure S50. Get High-res Image Gene #16: 'amp_17q24.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D16V7.png)
P value = 0.00036 (Fisher's exact test), Q value = 0.21
Table S51. Gene #16: 'amp_17q24.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 16(17Q24.1) MUTATED | 38 | 10 | 50 |
AMP PEAK 16(17Q24.1) WILD-TYPE | 126 | 88 | 111 |
Figure S51. Get High-res Image Gene #16: 'amp_17q24.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D16V8.png)
P value = 6.89e-06 (Fisher's exact test), Q value = 0.0046
Table S52. Gene #17: 'amp_19p13.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 17(19P13.2) MUTATED | 46 | 16 | 8 |
AMP PEAK 17(19P13.2) WILD-TYPE | 125 | 179 | 53 |
Figure S52. Get High-res Image Gene #17: 'amp_19p13.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D17V3.png)
P value = 2.77e-05 (Fisher's exact test), Q value = 0.018
Table S53. Gene #18: 'amp_19q13.11' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 18(19Q13.11) MUTATED | 54 | 24 | 10 |
AMP PEAK 18(19Q13.11) WILD-TYPE | 117 | 171 | 51 |
Figure S53. Get High-res Image Gene #18: 'amp_19q13.11' versus Molecular Subtype #3: 'CN_CNMF'
![](D18V3.png)
P value = 0.000396 (Fisher's exact test), Q value = 0.23
Table S54. Gene #19: 'amp_20p11.23' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 19(20P11.23) MUTATED | 36 | 11 | 26 |
AMP PEAK 19(20P11.23) WILD-TYPE | 20 | 32 | 21 |
Figure S54. Get High-res Image Gene #19: 'amp_20p11.23' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D19V2.png)
P value = 2.68e-10 (Fisher's exact test), Q value = 1.9e-07
Table S55. Gene #19: 'amp_20p11.23' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 19(20P11.23) MUTATED | 114 | 63 | 32 |
AMP PEAK 19(20P11.23) WILD-TYPE | 57 | 132 | 29 |
Figure S55. Get High-res Image Gene #19: 'amp_20p11.23' versus Molecular Subtype #3: 'CN_CNMF'
![](D19V3.png)
P value = 1.09e-06 (Chi-square test), Q value = 0.00074
Table S56. Gene #19: 'amp_20p11.23' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 19(20P11.23) MUTATED | 22 | 67 | 31 | 22 | 64 |
AMP PEAK 19(20P11.23) WILD-TYPE | 11 | 46 | 40 | 68 | 52 |
Figure S56. Get High-res Image Gene #19: 'amp_20p11.23' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D19V7.png)
P value = 0.000341 (Fisher's exact test), Q value = 0.2
Table S57. Gene #19: 'amp_20p11.23' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 19(20P11.23) MUTATED | 84 | 31 | 91 |
AMP PEAK 19(20P11.23) WILD-TYPE | 80 | 67 | 70 |
Figure S57. Get High-res Image Gene #19: 'amp_20p11.23' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D19V8.png)
P value = 7.72e-10 (Fisher's exact test), Q value = 5.6e-07
Table S58. Gene #20: 'amp_20q11.21' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
AMP PEAK 20(20Q11.21) MUTATED | 13 | 58 | 16 | 18 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 22 | 3 | 13 | 3 |
Figure S58. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D20V1.png)
P value = 1.47e-11 (Fisher's exact test), Q value = 1.1e-08
Table S59. Gene #20: 'amp_20q11.21' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 20(20Q11.21) MUTATED | 50 | 13 | 42 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 6 | 30 | 5 |
Figure S59. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D20V2.png)
P value = 4.38e-39 (Fisher's exact test), Q value = 3.5e-36
Table S60. Gene #20: 'amp_20q11.21' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 20(20Q11.21) MUTATED | 170 | 84 | 52 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 1 | 111 | 9 |
Figure S60. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #3: 'CN_CNMF'
![](D20V3.png)
P value = 2.13e-12 (Fisher's exact test), Q value = 1.6e-09
Table S61. Gene #20: 'amp_20q11.21' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 20(20Q11.21) MUTATED | 107 | 46 | 42 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 7 | 42 | 26 |
Figure S61. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D20V4.png)
P value = 0.000114 (Fisher's exact test), Q value = 0.071
Table S62. Gene #20: 'amp_20q11.21' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 26 | 56 | 63 | 180 |
AMP PEAK 20(20Q11.21) MUTATED | 13 | 29 | 53 | 133 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 13 | 27 | 10 | 47 |
Figure S62. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
![](D20V6.png)
P value = 2.93e-23 (Chi-square test), Q value = 2.3e-20
Table S63. Gene #20: 'amp_20q11.21' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 20(20Q11.21) MUTATED | 26 | 110 | 50 | 28 | 89 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 7 | 3 | 21 | 62 | 27 |
Figure S63. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D20V7.png)
P value = 2.01e-21 (Fisher's exact test), Q value = 1.6e-18
Table S64. Gene #20: 'amp_20q11.21' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 20(20Q11.21) MUTATED | 118 | 36 | 149 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 46 | 62 | 12 |
Figure S64. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D20V8.png)
P value = 0.000105 (Fisher's exact test), Q value = 0.066
Table S65. Gene #20: 'amp_20q11.21' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 80 | 174 | 143 |
AMP PEAK 20(20Q11.21) MUTATED | 43 | 125 | 116 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 37 | 49 | 27 |
Figure S65. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
![](D20V10.png)
P value = 2.36e-12 (Fisher's exact test), Q value = 1.8e-09
Table S66. Gene #20: 'amp_20q11.21' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 20(20Q11.21) MUTATED | 74 | 34 | 51 |
AMP PEAK 20(20Q11.21) WILD-TYPE | 5 | 44 | 12 |
Figure S66. Get High-res Image Gene #20: 'amp_20q11.21' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D20V11.png)
P value = 8.9e-11 (Fisher's exact test), Q value = 6.5e-08
Table S67. Gene #21: 'amp_20q12' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
AMP PEAK 21(20Q12) MUTATED | 12 | 58 | 15 | 18 |
AMP PEAK 21(20Q12) WILD-TYPE | 23 | 3 | 14 | 3 |
Figure S67. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D21V1.png)
P value = 7.64e-12 (Fisher's exact test), Q value = 5.7e-09
Table S68. Gene #21: 'amp_20q12' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 21(20Q12) MUTATED | 49 | 12 | 42 |
AMP PEAK 21(20Q12) WILD-TYPE | 7 | 31 | 5 |
Figure S68. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D21V2.png)
P value = 2.02e-40 (Fisher's exact test), Q value = 1.6e-37
Table S69. Gene #21: 'amp_20q12' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 21(20Q12) MUTATED | 170 | 83 | 54 |
AMP PEAK 21(20Q12) WILD-TYPE | 1 | 112 | 7 |
Figure S69. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #3: 'CN_CNMF'
![](D21V3.png)
P value = 1.84e-11 (Fisher's exact test), Q value = 1.4e-08
Table S70. Gene #21: 'amp_20q12' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 21(20Q12) MUTATED | 107 | 48 | 43 |
AMP PEAK 21(20Q12) WILD-TYPE | 7 | 40 | 25 |
Figure S70. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D21V4.png)
P value = 2.33e-05 (Fisher's exact test), Q value = 0.015
Table S71. Gene #21: 'amp_20q12' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 26 | 56 | 63 | 180 |
AMP PEAK 21(20Q12) MUTATED | 13 | 29 | 55 | 132 |
AMP PEAK 21(20Q12) WILD-TYPE | 13 | 27 | 8 | 48 |
Figure S71. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
![](D21V6.png)
P value = 2.3e-22 (Chi-square test), Q value = 1.8e-19
Table S72. Gene #21: 'amp_20q12' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 21(20Q12) MUTATED | 26 | 110 | 52 | 29 | 87 |
AMP PEAK 21(20Q12) WILD-TYPE | 7 | 3 | 19 | 61 | 29 |
Figure S72. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D21V7.png)
P value = 6.78e-21 (Fisher's exact test), Q value = 5.3e-18
Table S73. Gene #21: 'amp_20q12' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 21(20Q12) MUTATED | 116 | 38 | 150 |
AMP PEAK 21(20Q12) WILD-TYPE | 48 | 60 | 11 |
Figure S73. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D21V8.png)
P value = 0.000127 (Fisher's exact test), Q value = 0.078
Table S74. Gene #21: 'amp_20q12' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 80 | 174 | 143 |
AMP PEAK 21(20Q12) MUTATED | 44 | 124 | 117 |
AMP PEAK 21(20Q12) WILD-TYPE | 36 | 50 | 26 |
Figure S74. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
![](D21V10.png)
P value = 2.32e-13 (Fisher's exact test), Q value = 1.8e-10
Table S75. Gene #21: 'amp_20q12' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 21(20Q12) MUTATED | 75 | 34 | 52 |
AMP PEAK 21(20Q12) WILD-TYPE | 4 | 44 | 11 |
Figure S75. Get High-res Image Gene #21: 'amp_20q12' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D21V11.png)
P value = 1.49e-09 (Fisher's exact test), Q value = 1.1e-06
Table S76. Gene #22: 'amp_20q13.32' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
AMP PEAK 22(20Q13.32) MUTATED | 13 | 58 | 17 | 18 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 22 | 3 | 12 | 3 |
Figure S76. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D22V1.png)
P value = 4.32e-12 (Fisher's exact test), Q value = 3.2e-09
Table S77. Gene #22: 'amp_20q13.32' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
AMP PEAK 22(20Q13.32) MUTATED | 51 | 13 | 42 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 5 | 30 | 5 |
Figure S77. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D22V2.png)
P value = 6.54e-41 (Fisher's exact test), Q value = 5.2e-38
Table S78. Gene #22: 'amp_20q13.32' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
AMP PEAK 22(20Q13.32) MUTATED | 170 | 84 | 56 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 1 | 111 | 5 |
Figure S78. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #3: 'CN_CNMF'
![](D22V3.png)
P value = 1.84e-11 (Fisher's exact test), Q value = 1.4e-08
Table S79. Gene #22: 'amp_20q13.32' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
AMP PEAK 22(20Q13.32) MUTATED | 107 | 48 | 43 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 7 | 40 | 25 |
Figure S79. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D22V4.png)
P value = 1.41e-05 (Fisher's exact test), Q value = 0.0093
Table S80. Gene #22: 'amp_20q13.32' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 26 | 56 | 63 | 180 |
AMP PEAK 22(20Q13.32) MUTATED | 13 | 29 | 55 | 135 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 13 | 27 | 8 | 45 |
Figure S80. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
![](D22V6.png)
P value = 4.87e-22 (Chi-square test), Q value = 3.8e-19
Table S81. Gene #22: 'amp_20q13.32' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
AMP PEAK 22(20Q13.32) MUTATED | 26 | 110 | 52 | 30 | 89 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 7 | 3 | 19 | 60 | 27 |
Figure S81. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D22V7.png)
P value = 7.33e-21 (Fisher's exact test), Q value = 5.7e-18
Table S82. Gene #22: 'amp_20q13.32' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
AMP PEAK 22(20Q13.32) MUTATED | 119 | 38 | 150 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 45 | 60 | 11 |
Figure S82. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D22V8.png)
P value = 0.000275 (Fisher's exact test), Q value = 0.16
Table S83. Gene #22: 'amp_20q13.32' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 80 | 174 | 143 |
AMP PEAK 22(20Q13.32) MUTATED | 45 | 126 | 117 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 35 | 48 | 26 |
Figure S83. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
![](D22V10.png)
P value = 7.98e-13 (Fisher's exact test), Q value = 6e-10
Table S84. Gene #22: 'amp_20q13.32' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
AMP PEAK 22(20Q13.32) MUTATED | 75 | 35 | 52 |
AMP PEAK 22(20Q13.32) WILD-TYPE | 4 | 43 | 11 |
Figure S84. Get High-res Image Gene #22: 'amp_20q13.32' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D22V11.png)
P value = 8.23e-05 (Fisher's exact test), Q value = 0.052
Table S85. Gene #23: 'del_1p36.11' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 1(1P36.11) MUTATED | 9 | 36 | 4 | 10 |
DEL PEAK 1(1P36.11) WILD-TYPE | 26 | 25 | 25 | 11 |
Figure S85. Get High-res Image Gene #23: 'del_1p36.11' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D23V1.png)
P value = 3.57e-15 (Fisher's exact test), Q value = 2.7e-12
Table S86. Gene #23: 'del_1p36.11' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 1(1P36.11) MUTATED | 102 | 37 | 20 |
DEL PEAK 1(1P36.11) WILD-TYPE | 69 | 158 | 41 |
Figure S86. Get High-res Image Gene #23: 'del_1p36.11' versus Molecular Subtype #3: 'CN_CNMF'
![](D23V3.png)
P value = 3.19e-06 (Fisher's exact test), Q value = 0.0022
Table S87. Gene #23: 'del_1p36.11' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 1(1P36.11) MUTATED | 60 | 17 | 21 |
DEL PEAK 1(1P36.11) WILD-TYPE | 54 | 71 | 47 |
Figure S87. Get High-res Image Gene #23: 'del_1p36.11' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D23V4.png)
P value = 7.21e-08 (Chi-square test), Q value = 5.1e-05
Table S88. Gene #23: 'del_1p36.11' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 1(1P36.11) MUTATED | 11 | 58 | 27 | 10 | 52 |
DEL PEAK 1(1P36.11) WILD-TYPE | 22 | 55 | 44 | 80 | 64 |
Figure S88. Get High-res Image Gene #23: 'del_1p36.11' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D23V7.png)
P value = 4.94e-09 (Fisher's exact test), Q value = 3.5e-06
Table S89. Gene #23: 'del_1p36.11' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 1(1P36.11) MUTATED | 65 | 13 | 80 |
DEL PEAK 1(1P36.11) WILD-TYPE | 99 | 85 | 81 |
Figure S89. Get High-res Image Gene #23: 'del_1p36.11' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D23V8.png)
P value = 1.81e-05 (Fisher's exact test), Q value = 0.012
Table S90. Gene #23: 'del_1p36.11' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 1(1P36.11) MUTATED | 39 | 13 | 28 |
DEL PEAK 1(1P36.11) WILD-TYPE | 40 | 65 | 35 |
Figure S90. Get High-res Image Gene #23: 'del_1p36.11' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D23V11.png)
P value = 4.34e-13 (Fisher's exact test), Q value = 3.3e-10
Table S91. Gene #24: 'del_1p33' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 2(1P33) MUTATED | 80 | 28 | 7 |
DEL PEAK 2(1P33) WILD-TYPE | 91 | 167 | 54 |
Figure S91. Get High-res Image Gene #24: 'del_1p33' versus Molecular Subtype #3: 'CN_CNMF'
![](D24V3.png)
P value = 0.000128 (Fisher's exact test), Q value = 0.079
Table S92. Gene #24: 'del_1p33' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 2(1P33) MUTATED | 44 | 11 | 18 |
DEL PEAK 2(1P33) WILD-TYPE | 70 | 77 | 50 |
Figure S92. Get High-res Image Gene #24: 'del_1p33' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D24V4.png)
P value = 3.39e-05 (Fisher's exact test), Q value = 0.022
Table S93. Gene #24: 'del_1p33' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 2(1P33) MUTATED | 45 | 11 | 58 |
DEL PEAK 2(1P33) WILD-TYPE | 119 | 87 | 103 |
Figure S93. Get High-res Image Gene #24: 'del_1p33' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D24V8.png)
P value = 5.97e-12 (Fisher's exact test), Q value = 4.4e-09
Table S94. Gene #25: 'del_1p13.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 3(1P13.1) MUTATED | 75 | 31 | 4 |
DEL PEAK 3(1P13.1) WILD-TYPE | 96 | 164 | 57 |
Figure S94. Get High-res Image Gene #25: 'del_1p13.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D25V3.png)
P value = 2.09e-06 (Fisher's exact test), Q value = 0.0014
Table S95. Gene #26: 'del_1q43' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 4(1Q43) MUTATED | 36 | 8 | 7 |
DEL PEAK 4(1Q43) WILD-TYPE | 135 | 187 | 54 |
Figure S95. Get High-res Image Gene #26: 'del_1q43' versus Molecular Subtype #3: 'CN_CNMF'
![](D26V3.png)
P value = 9.6e-06 (Fisher's exact test), Q value = 0.0064
Table S96. Gene #26: 'del_1q43' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 4(1Q43) MUTATED | 15 | 2 | 33 |
DEL PEAK 4(1Q43) WILD-TYPE | 149 | 96 | 128 |
Figure S96. Get High-res Image Gene #26: 'del_1q43' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D26V8.png)
P value = 2.58e-05 (Fisher's exact test), Q value = 0.017
Table S97. Gene #30: 'del_3p26.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 8(3P26.1) MUTATED | 43 | 17 | 5 |
DEL PEAK 8(3P26.1) WILD-TYPE | 128 | 178 | 56 |
Figure S97. Get High-res Image Gene #30: 'del_3p26.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D30V3.png)
P value = 0.000144 (Fisher's exact test), Q value = 0.088
Table S98. Gene #32: 'del_3q26.31' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 10(3Q26.31) MUTATED | 30 | 13 | 1 |
DEL PEAK 10(3Q26.31) WILD-TYPE | 141 | 182 | 60 |
Figure S98. Get High-res Image Gene #32: 'del_3q26.31' versus Molecular Subtype #3: 'CN_CNMF'
![](D32V3.png)
P value = 6.15e-14 (Fisher's exact test), Q value = 4.7e-11
Table S99. Gene #33: 'del_4p16.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 11(4P16.2) MUTATED | 87 | 28 | 13 |
DEL PEAK 11(4P16.2) WILD-TYPE | 84 | 167 | 48 |
Figure S99. Get High-res Image Gene #33: 'del_4p16.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D33V3.png)
P value = 5.77e-06 (Chi-square test), Q value = 0.0039
Table S100. Gene #33: 'del_4p16.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 11(4P16.2) MUTATED | 8 | 44 | 25 | 7 | 43 |
DEL PEAK 11(4P16.2) WILD-TYPE | 25 | 69 | 46 | 83 | 73 |
Figure S100. Get High-res Image Gene #33: 'del_4p16.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D33V7.png)
P value = 2.82e-08 (Fisher's exact test), Q value = 2e-05
Table S101. Gene #33: 'del_4p16.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 11(4P16.2) MUTATED | 56 | 8 | 63 |
DEL PEAK 11(4P16.2) WILD-TYPE | 108 | 90 | 98 |
Figure S101. Get High-res Image Gene #33: 'del_4p16.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D33V8.png)
P value = 0.000138 (Fisher's exact test), Q value = 0.085
Table S102. Gene #33: 'del_4p16.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 11(4P16.2) MUTATED | 27 | 8 | 23 |
DEL PEAK 11(4P16.2) WILD-TYPE | 52 | 70 | 40 |
Figure S102. Get High-res Image Gene #33: 'del_4p16.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D33V11.png)
P value = 0.000412 (Fisher's exact test), Q value = 0.24
Table S103. Gene #34: 'del_4q22.1' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 12(4Q22.1) MUTATED | 9 | 27 | 2 | 11 |
DEL PEAK 12(4Q22.1) WILD-TYPE | 26 | 34 | 27 | 10 |
Figure S103. Get High-res Image Gene #34: 'del_4q22.1' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D34V1.png)
P value = 2.75e-14 (Fisher's exact test), Q value = 2.1e-11
Table S104. Gene #34: 'del_4q22.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 12(4Q22.1) MUTATED | 92 | 32 | 13 |
DEL PEAK 12(4Q22.1) WILD-TYPE | 79 | 163 | 48 |
Figure S104. Get High-res Image Gene #34: 'del_4q22.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D34V3.png)
P value = 1.05e-06 (Chi-square test), Q value = 0.00072
Table S105. Gene #34: 'del_4q22.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 12(4Q22.1) MUTATED | 12 | 47 | 22 | 7 | 47 |
DEL PEAK 12(4Q22.1) WILD-TYPE | 21 | 66 | 49 | 83 | 69 |
Figure S105. Get High-res Image Gene #34: 'del_4q22.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D34V7.png)
P value = 2.3e-07 (Fisher's exact test), Q value = 0.00016
Table S106. Gene #34: 'del_4q22.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 12(4Q22.1) MUTATED | 56 | 11 | 68 |
DEL PEAK 12(4Q22.1) WILD-TYPE | 108 | 87 | 93 |
Figure S106. Get High-res Image Gene #34: 'del_4q22.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D34V8.png)
P value = 0.000181 (Fisher's exact test), Q value = 0.11
Table S107. Gene #34: 'del_4q22.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 12(4Q22.1) MUTATED | 34 | 11 | 22 |
DEL PEAK 12(4Q22.1) WILD-TYPE | 45 | 67 | 41 |
Figure S107. Get High-res Image Gene #34: 'del_4q22.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D34V11.png)
P value = 3.65e-15 (Fisher's exact test), Q value = 2.8e-12
Table S108. Gene #35: 'del_4q35.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 13(4Q35.1) MUTATED | 96 | 32 | 17 |
DEL PEAK 13(4Q35.1) WILD-TYPE | 75 | 163 | 44 |
Figure S108. Get High-res Image Gene #35: 'del_4q35.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D35V3.png)
P value = 3.67e-06 (Fisher's exact test), Q value = 0.0025
Table S109. Gene #35: 'del_4q35.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 13(4Q35.1) MUTATED | 52 | 12 | 24 |
DEL PEAK 13(4Q35.1) WILD-TYPE | 62 | 76 | 44 |
Figure S109. Get High-res Image Gene #35: 'del_4q35.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D35V4.png)
P value = 4.39e-05 (Chi-square test), Q value = 0.028
Table S110. Gene #35: 'del_4q35.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 13(4Q35.1) MUTATED | 13 | 48 | 25 | 11 | 47 |
DEL PEAK 13(4Q35.1) WILD-TYPE | 20 | 65 | 46 | 79 | 69 |
Figure S110. Get High-res Image Gene #35: 'del_4q35.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D35V7.png)
P value = 8.19e-07 (Fisher's exact test), Q value = 0.00056
Table S111. Gene #35: 'del_4q35.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 13(4Q35.1) MUTATED | 62 | 13 | 69 |
DEL PEAK 13(4Q35.1) WILD-TYPE | 102 | 85 | 92 |
Figure S111. Get High-res Image Gene #35: 'del_4q35.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D35V8.png)
P value = 1.43e-06 (Fisher's exact test), Q value = 0.00098
Table S112. Gene #35: 'del_4q35.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 13(4Q35.1) MUTATED | 35 | 8 | 25 |
DEL PEAK 13(4Q35.1) WILD-TYPE | 44 | 70 | 38 |
Figure S112. Get High-res Image Gene #35: 'del_4q35.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D35V11.png)
P value = 2.32e-10 (Fisher's exact test), Q value = 1.7e-07
Table S113. Gene #36: 'del_5q11.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 14(5Q11.2) MUTATED | 62 | 17 | 18 |
DEL PEAK 14(5Q11.2) WILD-TYPE | 109 | 178 | 43 |
Figure S113. Get High-res Image Gene #36: 'del_5q11.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D36V3.png)
P value = 0.000151 (Chi-square test), Q value = 0.092
Table S114. Gene #36: 'del_5q11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 14(5Q11.2) MUTATED | 10 | 31 | 18 | 4 | 34 |
DEL PEAK 14(5Q11.2) WILD-TYPE | 23 | 82 | 53 | 86 | 82 |
Figure S114. Get High-res Image Gene #36: 'del_5q11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D36V7.png)
P value = 1.27e-06 (Fisher's exact test), Q value = 0.00087
Table S115. Gene #36: 'del_5q11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 14(5Q11.2) MUTATED | 39 | 6 | 52 |
DEL PEAK 14(5Q11.2) WILD-TYPE | 125 | 92 | 109 |
Figure S115. Get High-res Image Gene #36: 'del_5q11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D36V8.png)
P value = 9.16e-05 (Fisher's exact test), Q value = 0.058
Table S116. Gene #36: 'del_5q11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 14(5Q11.2) MUTATED | 25 | 5 | 17 |
DEL PEAK 14(5Q11.2) WILD-TYPE | 54 | 73 | 46 |
Figure S116. Get High-res Image Gene #36: 'del_5q11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D36V11.png)
P value = 1.22e-11 (Fisher's exact test), Q value = 9.1e-09
Table S117. Gene #37: 'del_5q21.3' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 15(5Q21.3) MUTATED | 75 | 24 | 23 |
DEL PEAK 15(5Q21.3) WILD-TYPE | 96 | 171 | 38 |
Figure S117. Get High-res Image Gene #37: 'del_5q21.3' versus Molecular Subtype #3: 'CN_CNMF'
![](D37V3.png)
P value = 0.000142 (Fisher's exact test), Q value = 0.087
Table S118. Gene #37: 'del_5q21.3' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 15(5Q21.3) MUTATED | 49 | 13 | 59 |
DEL PEAK 15(5Q21.3) WILD-TYPE | 115 | 85 | 102 |
Figure S118. Get High-res Image Gene #37: 'del_5q21.3' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D37V8.png)
P value = 1.31e-10 (Fisher's exact test), Q value = 9.6e-08
Table S119. Gene #38: 'del_5q23.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 16(5Q23.1) MUTATED | 68 | 22 | 23 |
DEL PEAK 16(5Q23.1) WILD-TYPE | 103 | 173 | 38 |
Figure S119. Get High-res Image Gene #38: 'del_5q23.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D38V3.png)
P value = 0.000318 (Chi-square test), Q value = 0.19
Table S120. Gene #38: 'del_5q23.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 16(5Q23.1) MUTATED | 10 | 41 | 18 | 8 | 35 |
DEL PEAK 16(5Q23.1) WILD-TYPE | 23 | 72 | 53 | 82 | 81 |
Figure S120. Get High-res Image Gene #38: 'del_5q23.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D38V7.png)
P value = 3.43e-05 (Fisher's exact test), Q value = 0.022
Table S121. Gene #38: 'del_5q23.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 16(5Q23.1) MUTATED | 43 | 11 | 58 |
DEL PEAK 16(5Q23.1) WILD-TYPE | 121 | 87 | 103 |
Figure S121. Get High-res Image Gene #38: 'del_5q23.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D38V8.png)
P value = 6.46e-05 (Fisher's exact test), Q value = 0.041
Table S122. Gene #42: 'del_8p23.3' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 20(8P23.3) MUTATED | 19 | 11 | 32 |
DEL PEAK 20(8P23.3) WILD-TYPE | 37 | 32 | 15 |
Figure S122. Get High-res Image Gene #42: 'del_8p23.3' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D42V2.png)
P value = 2.89e-22 (Fisher's exact test), Q value = 2.3e-19
Table S123. Gene #42: 'del_8p23.3' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 20(8P23.3) MUTATED | 101 | 32 | 43 |
DEL PEAK 20(8P23.3) WILD-TYPE | 70 | 163 | 18 |
Figure S123. Get High-res Image Gene #42: 'del_8p23.3' versus Molecular Subtype #3: 'CN_CNMF'
![](D42V3.png)
P value = 3.4e-07 (Fisher's exact test), Q value = 0.00024
Table S124. Gene #42: 'del_8p23.3' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 20(8P23.3) MUTATED | 68 | 20 | 24 |
DEL PEAK 20(8P23.3) WILD-TYPE | 46 | 68 | 44 |
Figure S124. Get High-res Image Gene #42: 'del_8p23.3' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D42V4.png)
P value = 4.67e-07 (Chi-square test), Q value = 0.00032
Table S125. Gene #42: 'del_8p23.3' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 20(8P23.3) MUTATED | 15 | 56 | 34 | 13 | 58 |
DEL PEAK 20(8P23.3) WILD-TYPE | 18 | 57 | 37 | 77 | 58 |
Figure S125. Get High-res Image Gene #42: 'del_8p23.3' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D42V7.png)
P value = 3.06e-09 (Fisher's exact test), Q value = 2.2e-06
Table S126. Gene #42: 'del_8p23.3' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 20(8P23.3) MUTATED | 73 | 16 | 87 |
DEL PEAK 20(8P23.3) WILD-TYPE | 91 | 82 | 74 |
Figure S126. Get High-res Image Gene #42: 'del_8p23.3' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D42V8.png)
P value = 2.22e-07 (Fisher's exact test), Q value = 0.00016
Table S127. Gene #42: 'del_8p23.3' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 20(8P23.3) MUTATED | 46 | 14 | 32 |
DEL PEAK 20(8P23.3) WILD-TYPE | 33 | 64 | 31 |
Figure S127. Get High-res Image Gene #42: 'del_8p23.3' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D42V11.png)
P value = 0.000179 (Fisher's exact test), Q value = 0.11
Table S128. Gene #43: 'del_8p22' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 21(8P22) MUTATED | 25 | 9 | 30 |
DEL PEAK 21(8P22) WILD-TYPE | 31 | 34 | 17 |
Figure S128. Get High-res Image Gene #43: 'del_8p22' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D43V2.png)
P value = 5.76e-28 (Fisher's exact test), Q value = 4.6e-25
Table S129. Gene #43: 'del_8p22' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 21(8P22) MUTATED | 111 | 32 | 47 |
DEL PEAK 21(8P22) WILD-TYPE | 60 | 163 | 14 |
Figure S129. Get High-res Image Gene #43: 'del_8p22' versus Molecular Subtype #3: 'CN_CNMF'
![](D43V3.png)
P value = 3.92e-08 (Fisher's exact test), Q value = 2.8e-05
Table S130. Gene #43: 'del_8p22' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 21(8P22) MUTATED | 75 | 23 | 26 |
DEL PEAK 21(8P22) WILD-TYPE | 39 | 65 | 42 |
Figure S130. Get High-res Image Gene #43: 'del_8p22' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D43V4.png)
P value = 0.000135 (Fisher's exact test), Q value = 0.083
Table S131. Gene #43: 'del_8p22' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 26 | 56 | 63 | 180 |
DEL PEAK 21(8P22) MUTATED | 5 | 15 | 38 | 82 |
DEL PEAK 21(8P22) WILD-TYPE | 21 | 41 | 25 | 98 |
Figure S131. Get High-res Image Gene #43: 'del_8p22' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
![](D43V6.png)
P value = 2.22e-08 (Chi-square test), Q value = 1.6e-05
Table S132. Gene #43: 'del_8p22' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 21(8P22) MUTATED | 16 | 65 | 36 | 14 | 59 |
DEL PEAK 21(8P22) WILD-TYPE | 17 | 48 | 35 | 76 | 57 |
Figure S132. Get High-res Image Gene #43: 'del_8p22' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D43V7.png)
P value = 4.66e-09 (Fisher's exact test), Q value = 3.3e-06
Table S133. Gene #43: 'del_8p22' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 21(8P22) MUTATED | 75 | 20 | 95 |
DEL PEAK 21(8P22) WILD-TYPE | 89 | 78 | 66 |
Figure S133. Get High-res Image Gene #43: 'del_8p22' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D43V8.png)
P value = 3.42e-07 (Fisher's exact test), Q value = 0.00024
Table S134. Gene #43: 'del_8p22' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 21(8P22) MUTATED | 50 | 18 | 36 |
DEL PEAK 21(8P22) WILD-TYPE | 29 | 60 | 27 |
Figure S134. Get High-res Image Gene #43: 'del_8p22' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D43V11.png)
P value = 1.3e-05 (Fisher's exact test), Q value = 0.0086
Table S135. Gene #44: 'del_8p11.21' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 22(8P11.21) MUTATED | 32 | 11 | 1 |
DEL PEAK 22(8P11.21) WILD-TYPE | 139 | 184 | 60 |
Figure S135. Get High-res Image Gene #44: 'del_8p11.21' versus Molecular Subtype #3: 'CN_CNMF'
![](D44V3.png)
P value = 4.85e-07 (Fisher's exact test), Q value = 0.00033
Table S136. Gene #46: 'del_10p15.3' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 24(10P15.3) MUTATED | 46 | 14 | 15 |
DEL PEAK 24(10P15.3) WILD-TYPE | 125 | 181 | 46 |
Figure S136. Get High-res Image Gene #46: 'del_10p15.3' versus Molecular Subtype #3: 'CN_CNMF'
![](D46V3.png)
P value = 0.000108 (Fisher's exact test), Q value = 0.068
Table S137. Gene #46: 'del_10p15.3' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 24(10P15.3) MUTATED | 26 | 6 | 42 |
DEL PEAK 24(10P15.3) WILD-TYPE | 138 | 92 | 119 |
Figure S137. Get High-res Image Gene #46: 'del_10p15.3' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D46V8.png)
P value = 2.13e-10 (Fisher's exact test), Q value = 1.5e-07
Table S138. Gene #47: 'del_10q21.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 25(10Q21.1) MUTATED | 60 | 15 | 15 |
DEL PEAK 25(10Q21.1) WILD-TYPE | 111 | 180 | 46 |
Figure S138. Get High-res Image Gene #47: 'del_10q21.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D47V3.png)
P value = 0.000404 (Fisher's exact test), Q value = 0.24
Table S139. Gene #47: 'del_10q21.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 25(10Q21.1) MUTATED | 33 | 9 | 47 |
DEL PEAK 25(10Q21.1) WILD-TYPE | 131 | 89 | 114 |
Figure S139. Get High-res Image Gene #47: 'del_10q21.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D47V8.png)
P value = 1.72e-07 (Fisher's exact test), Q value = 0.00012
Table S140. Gene #48: 'del_10q23.31' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 26(10Q23.31) MUTATED | 61 | 23 | 18 |
DEL PEAK 26(10Q23.31) WILD-TYPE | 110 | 172 | 43 |
Figure S140. Get High-res Image Gene #48: 'del_10q23.31' versus Molecular Subtype #3: 'CN_CNMF'
![](D48V3.png)
P value = 0.000106 (Fisher's exact test), Q value = 0.066
Table S141. Gene #48: 'del_10q23.31' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 26(10Q23.31) MUTATED | 27 | 7 | 21 |
DEL PEAK 26(10Q23.31) WILD-TYPE | 52 | 71 | 42 |
Figure S141. Get High-res Image Gene #48: 'del_10q23.31' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D48V11.png)
P value = 7.14e-10 (Fisher's exact test), Q value = 5.1e-07
Table S142. Gene #49: 'del_10q25.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 27(10Q25.2) MUTATED | 66 | 20 | 15 |
DEL PEAK 27(10Q25.2) WILD-TYPE | 105 | 175 | 46 |
Figure S142. Get High-res Image Gene #49: 'del_10q25.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D49V3.png)
P value = 3.15e-06 (Fisher's exact test), Q value = 0.0021
Table S143. Gene #49: 'del_10q25.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 27(10Q25.2) MUTATED | 40 | 7 | 53 |
DEL PEAK 27(10Q25.2) WILD-TYPE | 124 | 91 | 108 |
Figure S143. Get High-res Image Gene #49: 'del_10q25.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D49V8.png)
P value = 1.51e-06 (Fisher's exact test), Q value = 0.001
Table S144. Gene #49: 'del_10q25.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 27(10Q25.2) MUTATED | 29 | 4 | 18 |
DEL PEAK 27(10Q25.2) WILD-TYPE | 50 | 74 | 45 |
Figure S144. Get High-res Image Gene #49: 'del_10q25.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D49V11.png)
P value = 6.93e-11 (Fisher's exact test), Q value = 5.1e-08
Table S145. Gene #50: 'del_12p13.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 28(12P13.2) MUTATED | 42 | 4 | 8 |
DEL PEAK 28(12P13.2) WILD-TYPE | 129 | 191 | 53 |
Figure S145. Get High-res Image Gene #50: 'del_12p13.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D50V3.png)
P value = 1.11e-06 (Fisher's exact test), Q value = 0.00076
Table S146. Gene #52: 'del_14q32.11' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 30(14Q32.11) MUTATED | 8 | 36 | 2 | 11 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 27 | 25 | 27 | 10 |
Figure S146. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D52V1.png)
P value = 3.13e-05 (Fisher's exact test), Q value = 0.02
Table S147. Gene #52: 'del_14q32.11' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 30(14Q32.11) MUTATED | 23 | 6 | 28 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 33 | 37 | 19 |
Figure S147. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D52V2.png)
P value = 4.19e-25 (Fisher's exact test), Q value = 3.3e-22
Table S148. Gene #52: 'del_14q32.11' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 30(14Q32.11) MUTATED | 106 | 26 | 8 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 65 | 169 | 53 |
Figure S148. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #3: 'CN_CNMF'
![](D52V3.png)
P value = 0.000117 (Fisher's exact test), Q value = 0.073
Table S149. Gene #52: 'del_14q32.11' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 30(14Q32.11) MUTATED | 50 | 15 | 17 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 64 | 73 | 51 |
Figure S149. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D52V4.png)
P value = 4.38e-07 (Chi-square test), Q value = 3e-04
Table S150. Gene #52: 'del_14q32.11' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 30(14Q32.11) MUTATED | 9 | 49 | 19 | 10 | 53 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 24 | 64 | 52 | 80 | 63 |
Figure S150. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D52V7.png)
P value = 1.85e-07 (Fisher's exact test), Q value = 0.00013
Table S151. Gene #52: 'del_14q32.11' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 30(14Q32.11) MUTATED | 65 | 11 | 64 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 99 | 87 | 97 |
Figure S151. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D52V8.png)
P value = 0.000245 (Fisher's exact test), Q value = 0.15
Table S152. Gene #52: 'del_14q32.11' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 80 | 174 | 143 |
DEL PEAK 30(14Q32.11) MUTATED | 12 | 68 | 52 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 68 | 106 | 91 |
Figure S152. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
![](D52V10.png)
P value = 2.17e-05 (Fisher's exact test), Q value = 0.014
Table S153. Gene #52: 'del_14q32.11' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 30(14Q32.11) MUTATED | 34 | 9 | 22 |
DEL PEAK 30(14Q32.11) WILD-TYPE | 45 | 69 | 41 |
Figure S153. Get High-res Image Gene #52: 'del_14q32.11' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D52V11.png)
P value = 3.99e-22 (Fisher's exact test), Q value = 3.1e-19
Table S154. Gene #53: 'del_15q11.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 31(15Q11.2) MUTATED | 114 | 34 | 18 |
DEL PEAK 31(15Q11.2) WILD-TYPE | 57 | 161 | 43 |
Figure S154. Get High-res Image Gene #53: 'del_15q11.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D53V3.png)
P value = 2.65e-07 (Chi-square test), Q value = 0.00018
Table S155. Gene #53: 'del_15q11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 31(15Q11.2) MUTATED | 10 | 54 | 31 | 12 | 58 |
DEL PEAK 31(15Q11.2) WILD-TYPE | 23 | 59 | 40 | 78 | 58 |
Figure S155. Get High-res Image Gene #53: 'del_15q11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D53V7.png)
P value = 4.27e-09 (Fisher's exact test), Q value = 3e-06
Table S156. Gene #53: 'del_15q11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 31(15Q11.2) MUTATED | 69 | 14 | 82 |
DEL PEAK 31(15Q11.2) WILD-TYPE | 95 | 84 | 79 |
Figure S156. Get High-res Image Gene #53: 'del_15q11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D53V8.png)
P value = 2.84e-05 (Fisher's exact test), Q value = 0.018
Table S157. Gene #53: 'del_15q11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 31(15Q11.2) MUTATED | 40 | 15 | 31 |
DEL PEAK 31(15Q11.2) WILD-TYPE | 39 | 63 | 32 |
Figure S157. Get High-res Image Gene #53: 'del_15q11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D53V11.png)
P value = 5.66e-19 (Fisher's exact test), Q value = 4.4e-16
Table S158. Gene #54: 'del_15q21.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 32(15Q21.1) MUTATED | 107 | 34 | 17 |
DEL PEAK 32(15Q21.1) WILD-TYPE | 64 | 161 | 44 |
Figure S158. Get High-res Image Gene #54: 'del_15q21.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D54V3.png)
P value = 7.84e-08 (Chi-square test), Q value = 5.5e-05
Table S159. Gene #54: 'del_15q21.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 32(15Q21.1) MUTATED | 10 | 50 | 28 | 10 | 59 |
DEL PEAK 32(15Q21.1) WILD-TYPE | 23 | 63 | 43 | 80 | 57 |
Figure S159. Get High-res Image Gene #54: 'del_15q21.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D54V7.png)
P value = 4.02e-09 (Fisher's exact test), Q value = 2.9e-06
Table S160. Gene #54: 'del_15q21.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 32(15Q21.1) MUTATED | 69 | 12 | 76 |
DEL PEAK 32(15Q21.1) WILD-TYPE | 95 | 86 | 85 |
Figure S160. Get High-res Image Gene #54: 'del_15q21.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D54V8.png)
P value = 0.000132 (Fisher's exact test), Q value = 0.081
Table S161. Gene #54: 'del_15q21.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 32(15Q21.1) MUTATED | 36 | 14 | 29 |
DEL PEAK 32(15Q21.1) WILD-TYPE | 43 | 64 | 34 |
Figure S161. Get High-res Image Gene #54: 'del_15q21.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D54V11.png)
P value = 0.00016 (Fisher's exact test), Q value = 0.097
Table S162. Gene #55: 'del_15q22.33' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 33(15Q22.33) MUTATED | 8 | 32 | 3 | 10 |
DEL PEAK 33(15Q22.33) WILD-TYPE | 27 | 29 | 26 | 11 |
Figure S162. Get High-res Image Gene #55: 'del_15q22.33' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D55V1.png)
P value = 2.5e-22 (Fisher's exact test), Q value = 2e-19
Table S163. Gene #55: 'del_15q22.33' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 33(15Q22.33) MUTATED | 108 | 28 | 17 |
DEL PEAK 33(15Q22.33) WILD-TYPE | 63 | 167 | 44 |
Figure S163. Get High-res Image Gene #55: 'del_15q22.33' versus Molecular Subtype #3: 'CN_CNMF'
![](D55V3.png)
P value = 2.99e-05 (Fisher's exact test), Q value = 0.019
Table S164. Gene #55: 'del_15q22.33' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 33(15Q22.33) MUTATED | 57 | 17 | 24 |
DEL PEAK 33(15Q22.33) WILD-TYPE | 57 | 71 | 44 |
Figure S164. Get High-res Image Gene #55: 'del_15q22.33' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D55V4.png)
P value = 4.13e-08 (Chi-square test), Q value = 2.9e-05
Table S165. Gene #55: 'del_15q22.33' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 33(15Q22.33) MUTATED | 10 | 52 | 28 | 8 | 54 |
DEL PEAK 33(15Q22.33) WILD-TYPE | 23 | 61 | 43 | 82 | 62 |
Figure S165. Get High-res Image Gene #55: 'del_15q22.33' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D55V7.png)
P value = 6.26e-10 (Fisher's exact test), Q value = 4.5e-07
Table S166. Gene #55: 'del_15q22.33' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 33(15Q22.33) MUTATED | 62 | 11 | 79 |
DEL PEAK 33(15Q22.33) WILD-TYPE | 102 | 87 | 82 |
Figure S166. Get High-res Image Gene #55: 'del_15q22.33' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D55V8.png)
P value = 0.000102 (Fisher's exact test), Q value = 0.064
Table S167. Gene #55: 'del_15q22.33' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 80 | 174 | 143 |
DEL PEAK 33(15Q22.33) MUTATED | 14 | 62 | 65 |
DEL PEAK 33(15Q22.33) WILD-TYPE | 66 | 112 | 78 |
Figure S167. Get High-res Image Gene #55: 'del_15q22.33' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
![](D55V10.png)
P value = 3.2e-05 (Fisher's exact test), Q value = 0.021
Table S168. Gene #55: 'del_15q22.33' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 33(15Q22.33) MUTATED | 36 | 13 | 30 |
DEL PEAK 33(15Q22.33) WILD-TYPE | 43 | 65 | 33 |
Figure S168. Get High-res Image Gene #55: 'del_15q22.33' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D55V11.png)
P value = 2.85e-08 (Fisher's exact test), Q value = 2e-05
Table S169. Gene #58: 'del_17p12' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 36(17P12) MUTATED | 10 | 49 | 8 | 15 |
DEL PEAK 36(17P12) WILD-TYPE | 25 | 12 | 21 | 6 |
Figure S169. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D58V1.png)
P value = 5.25e-07 (Fisher's exact test), Q value = 0.00036
Table S170. Gene #58: 'del_17p12' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 36(17P12) MUTATED | 36 | 10 | 36 |
DEL PEAK 36(17P12) WILD-TYPE | 20 | 33 | 11 |
Figure S170. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D58V2.png)
P value = 2.19e-34 (Fisher's exact test), Q value = 1.7e-31
Table S171. Gene #58: 'del_17p12' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 36(17P12) MUTATED | 147 | 48 | 42 |
DEL PEAK 36(17P12) WILD-TYPE | 24 | 147 | 19 |
Figure S171. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #3: 'CN_CNMF'
![](D58V3.png)
P value = 1.25e-11 (Fisher's exact test), Q value = 9.3e-09
Table S172. Gene #58: 'del_17p12' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 36(17P12) MUTATED | 91 | 29 | 31 |
DEL PEAK 36(17P12) WILD-TYPE | 23 | 59 | 37 |
Figure S172. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D58V4.png)
P value = 0.000163 (Fisher's exact test), Q value = 0.099
Table S173. Gene #58: 'del_17p12' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 26 | 56 | 63 | 180 |
DEL PEAK 36(17P12) MUTATED | 8 | 20 | 43 | 106 |
DEL PEAK 36(17P12) WILD-TYPE | 18 | 36 | 20 | 74 |
Figure S173. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
![](D58V6.png)
P value = 9.24e-19 (Chi-square test), Q value = 7.1e-16
Table S174. Gene #58: 'del_17p12' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 36(17P12) MUTATED | 21 | 91 | 37 | 14 | 73 |
DEL PEAK 36(17P12) WILD-TYPE | 12 | 22 | 34 | 76 | 43 |
Figure S174. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D58V7.png)
P value = 1.67e-14 (Fisher's exact test), Q value = 1.3e-11
Table S175. Gene #58: 'del_17p12' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 36(17P12) MUTATED | 95 | 23 | 118 |
DEL PEAK 36(17P12) WILD-TYPE | 69 | 75 | 43 |
Figure S175. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D58V8.png)
P value = 2.38e-11 (Fisher's exact test), Q value = 1.7e-08
Table S176. Gene #58: 'del_17p12' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 36(17P12) MUTATED | 65 | 22 | 37 |
DEL PEAK 36(17P12) WILD-TYPE | 14 | 56 | 26 |
Figure S176. Get High-res Image Gene #58: 'del_17p12' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D58V11.png)
P value = 1.04e-11 (Fisher's exact test), Q value = 7.7e-09
Table S177. Gene #60: 'del_18p11.31' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 38(18P11.31) MUTATED | 6 | 50 | 7 | 15 |
DEL PEAK 38(18P11.31) WILD-TYPE | 29 | 11 | 22 | 6 |
Figure S177. Get High-res Image Gene #60: 'del_18p11.31' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D60V1.png)
P value = 7.75e-10 (Fisher's exact test), Q value = 5.6e-07
Table S178. Gene #60: 'del_18p11.31' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 38(18P11.31) MUTATED | 36 | 6 | 36 |
DEL PEAK 38(18P11.31) WILD-TYPE | 20 | 37 | 11 |
Figure S178. Get High-res Image Gene #60: 'del_18p11.31' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D60V2.png)
P value = 2.64e-42 (Fisher's exact test), Q value = 2.1e-39
Table S179. Gene #60: 'del_18p11.31' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 38(18P11.31) MUTATED | 153 | 41 | 36 |
DEL PEAK 38(18P11.31) WILD-TYPE | 18 | 154 | 25 |
Figure S179. Get High-res Image Gene #60: 'del_18p11.31' versus Molecular Subtype #3: 'CN_CNMF'
![](D60V3.png)
P value = 1.19e-15 (Fisher's exact test), Q value = 9.1e-13
Table S180. Gene #60: 'del_18p11.31' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 38(18P11.31) MUTATED | 93 | 22 | 34 |
DEL PEAK 38(18P11.31) WILD-TYPE | 21 | 66 | 34 |
Figure S180. Get High-res Image Gene #60: 'del_18p11.31' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D60V4.png)
P value = 4.52e-26 (Chi-square test), Q value = 3.6e-23
Table S181. Gene #60: 'del_18p11.31' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 38(18P11.31) MUTATED | 18 | 98 | 35 | 8 | 70 |
DEL PEAK 38(18P11.31) WILD-TYPE | 15 | 15 | 36 | 82 | 46 |
Figure S181. Get High-res Image Gene #60: 'del_18p11.31' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D60V7.png)
P value = 1.67e-24 (Fisher's exact test), Q value = 1.3e-21
Table S182. Gene #60: 'del_18p11.31' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 38(18P11.31) MUTATED | 91 | 13 | 125 |
DEL PEAK 38(18P11.31) WILD-TYPE | 73 | 85 | 36 |
Figure S182. Get High-res Image Gene #60: 'del_18p11.31' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D60V8.png)
P value = 2.02e-14 (Fisher's exact test), Q value = 1.5e-11
Table S183. Gene #60: 'del_18p11.31' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 38(18P11.31) MUTATED | 63 | 15 | 38 |
DEL PEAK 38(18P11.31) WILD-TYPE | 16 | 63 | 25 |
Figure S183. Get High-res Image Gene #60: 'del_18p11.31' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D60V11.png)
P value = 1.76e-11 (Fisher's exact test), Q value = 1.3e-08
Table S184. Gene #61: 'del_18q12.2' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 39(18Q12.2) MUTATED | 8 | 53 | 9 | 16 |
DEL PEAK 39(18Q12.2) WILD-TYPE | 27 | 8 | 20 | 5 |
Figure S184. Get High-res Image Gene #61: 'del_18q12.2' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D61V1.png)
P value = 2.8e-10 (Fisher's exact test), Q value = 2e-07
Table S185. Gene #61: 'del_18q12.2' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 39(18Q12.2) MUTATED | 39 | 8 | 39 |
DEL PEAK 39(18Q12.2) WILD-TYPE | 17 | 35 | 8 |
Figure S185. Get High-res Image Gene #61: 'del_18q12.2' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D61V2.png)
P value = 1.23e-43 (Fisher's exact test), Q value = 9.9e-41
Table S186. Gene #61: 'del_18q12.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 39(18Q12.2) MUTATED | 158 | 50 | 48 |
DEL PEAK 39(18Q12.2) WILD-TYPE | 13 | 145 | 13 |
Figure S186. Get High-res Image Gene #61: 'del_18q12.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D61V3.png)
P value = 1.39e-17 (Fisher's exact test), Q value = 1.1e-14
Table S187. Gene #61: 'del_18q12.2' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 39(18Q12.2) MUTATED | 102 | 29 | 34 |
DEL PEAK 39(18Q12.2) WILD-TYPE | 12 | 59 | 34 |
Figure S187. Get High-res Image Gene #61: 'del_18q12.2' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D61V4.png)
P value = 1.36e-23 (Chi-square test), Q value = 1.1e-20
Table S188. Gene #61: 'del_18q12.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 39(18Q12.2) MUTATED | 20 | 99 | 43 | 14 | 79 |
DEL PEAK 39(18Q12.2) WILD-TYPE | 13 | 14 | 28 | 76 | 37 |
Figure S188. Get High-res Image Gene #61: 'del_18q12.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D61V7.png)
P value = 6.27e-24 (Fisher's exact test), Q value = 5e-21
Table S189. Gene #61: 'del_18q12.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 39(18Q12.2) MUTATED | 100 | 20 | 135 |
DEL PEAK 39(18Q12.2) WILD-TYPE | 64 | 78 | 26 |
Figure S189. Get High-res Image Gene #61: 'del_18q12.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D61V8.png)
P value = 1.06e-14 (Fisher's exact test), Q value = 8.1e-12
Table S190. Gene #61: 'del_18q12.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 39(18Q12.2) MUTATED | 69 | 21 | 42 |
DEL PEAK 39(18Q12.2) WILD-TYPE | 10 | 57 | 21 |
Figure S190. Get High-res Image Gene #61: 'del_18q12.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D61V11.png)
P value = 5.08e-11 (Fisher's exact test), Q value = 3.7e-08
Table S191. Gene #62: 'del_18q21.2' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 40(18Q21.2) MUTATED | 8 | 53 | 10 | 16 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 27 | 8 | 19 | 5 |
Figure S191. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D62V1.png)
P value = 1.75e-10 (Fisher's exact test), Q value = 1.3e-07
Table S192. Gene #62: 'del_18q21.2' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 40(18Q21.2) MUTATED | 40 | 8 | 39 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 16 | 35 | 8 |
Figure S192. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D62V2.png)
P value = 2.05e-44 (Fisher's exact test), Q value = 1.6e-41
Table S193. Gene #62: 'del_18q21.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 40(18Q21.2) MUTATED | 161 | 56 | 52 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 10 | 139 | 9 |
Figure S193. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D62V3.png)
P value = 6.96e-14 (Fisher's exact test), Q value = 5.3e-11
Table S194. Gene #62: 'del_18q21.2' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 40(18Q21.2) MUTATED | 103 | 38 | 36 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 11 | 50 | 32 |
Figure S194. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D62V4.png)
P value = 0.000238 (Fisher's exact test), Q value = 0.14
Table S195. Gene #62: 'del_18q21.2' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 26 | 56 | 63 | 180 |
DEL PEAK 40(18Q21.2) MUTATED | 10 | 24 | 46 | 120 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 16 | 32 | 17 | 60 |
Figure S195. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
![](D62V6.png)
P value = 3.1e-19 (Chi-square test), Q value = 2.4e-16
Table S196. Gene #62: 'del_18q21.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 40(18Q21.2) MUTATED | 20 | 101 | 46 | 22 | 79 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 13 | 12 | 25 | 68 | 37 |
Figure S196. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D62V7.png)
P value = 2.42e-19 (Fisher's exact test), Q value = 1.9e-16
Table S197. Gene #62: 'del_18q21.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 40(18Q21.2) MUTATED | 101 | 29 | 138 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 63 | 69 | 23 |
Figure S197. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D62V8.png)
P value = 1.51e-13 (Fisher's exact test), Q value = 1.1e-10
Table S198. Gene #62: 'del_18q21.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 40(18Q21.2) MUTATED | 72 | 27 | 44 |
DEL PEAK 40(18Q21.2) WILD-TYPE | 7 | 51 | 19 |
Figure S198. Get High-res Image Gene #62: 'del_18q21.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D62V11.png)
P value = 1.3e-10 (Fisher's exact test), Q value = 9.5e-08
Table S199. Gene #63: 'del_18q22.1' versus Molecular Subtype #1: 'MRNA_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 35 | 61 | 29 | 21 |
DEL PEAK 41(18Q22.1) MUTATED | 8 | 53 | 11 | 16 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 27 | 8 | 18 | 5 |
Figure S199. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #1: 'MRNA_CNMF'
![](D63V1.png)
P value = 9.95e-10 (Fisher's exact test), Q value = 7.1e-07
Table S200. Gene #63: 'del_18q22.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 41(18Q22.1) MUTATED | 40 | 9 | 39 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 16 | 34 | 8 |
Figure S200. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D63V2.png)
P value = 1.41e-46 (Fisher's exact test), Q value = 1.1e-43
Table S201. Gene #63: 'del_18q22.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 41(18Q22.1) MUTATED | 163 | 55 | 51 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 8 | 140 | 10 |
Figure S201. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D63V3.png)
P value = 4.09e-14 (Fisher's exact test), Q value = 3.1e-11
Table S202. Gene #63: 'del_18q22.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 114 | 88 | 68 |
DEL PEAK 41(18Q22.1) MUTATED | 103 | 38 | 35 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 11 | 50 | 33 |
Figure S202. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #4: 'METHLYATION_CNMF'
![](D63V4.png)
P value = 0.000233 (Fisher's exact test), Q value = 0.14
Table S203. Gene #63: 'del_18q22.1' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
---|---|---|---|---|
ALL | 26 | 56 | 63 | 180 |
DEL PEAK 41(18Q22.1) MUTATED | 10 | 24 | 45 | 122 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 16 | 32 | 18 | 58 |
Figure S203. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
![](D63V6.png)
P value = 4.58e-18 (Chi-square test), Q value = 3.5e-15
Table S204. Gene #63: 'del_18q22.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 41(18Q22.1) MUTATED | 20 | 100 | 46 | 23 | 79 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 13 | 13 | 25 | 67 | 37 |
Figure S204. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D63V7.png)
P value = 8.21e-19 (Fisher's exact test), Q value = 6.3e-16
Table S205. Gene #63: 'del_18q22.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 41(18Q22.1) MUTATED | 102 | 29 | 137 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 62 | 69 | 24 |
Figure S205. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D63V8.png)
P value = 4.21e-14 (Fisher's exact test), Q value = 3.2e-11
Table S206. Gene #63: 'del_18q22.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 41(18Q22.1) MUTATED | 72 | 26 | 44 |
DEL PEAK 41(18Q22.1) WILD-TYPE | 7 | 52 | 19 |
Figure S206. Get High-res Image Gene #63: 'del_18q22.1' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D63V11.png)
P value = 1.91e-06 (Fisher's exact test), Q value = 0.0013
Table S207. Gene #65: 'del_20p12.1' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 43(20P12.1) MUTATED | 47 | 17 | 17 |
DEL PEAK 43(20P12.1) WILD-TYPE | 124 | 178 | 44 |
Figure S207. Get High-res Image Gene #65: 'del_20p12.1' versus Molecular Subtype #3: 'CN_CNMF'
![](D65V3.png)
P value = 6.19e-07 (Chi-square test), Q value = 0.00043
Table S208. Gene #65: 'del_20p12.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 43(20P12.1) MUTATED | 4 | 42 | 11 | 7 | 17 |
DEL PEAK 43(20P12.1) WILD-TYPE | 29 | 71 | 60 | 83 | 99 |
Figure S208. Get High-res Image Gene #65: 'del_20p12.1' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D65V7.png)
P value = 4.71e-06 (Fisher's exact test), Q value = 0.0032
Table S209. Gene #65: 'del_20p12.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 43(20P12.1) MUTATED | 27 | 6 | 48 |
DEL PEAK 43(20P12.1) WILD-TYPE | 137 | 92 | 113 |
Figure S209. Get High-res Image Gene #65: 'del_20p12.1' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D65V8.png)
P value = 2.16e-09 (Fisher's exact test), Q value = 1.5e-06
Table S210. Gene #66: 'del_21q11.2' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 44(21Q11.2) MUTATED | 83 | 37 | 13 |
DEL PEAK 44(21Q11.2) WILD-TYPE | 88 | 158 | 48 |
Figure S210. Get High-res Image Gene #66: 'del_21q11.2' versus Molecular Subtype #3: 'CN_CNMF'
![](D66V3.png)
P value = 0.000161 (Chi-square test), Q value = 0.098
Table S211. Gene #66: 'del_21q11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 44(21Q11.2) MUTATED | 6 | 48 | 23 | 13 | 42 |
DEL PEAK 44(21Q11.2) WILD-TYPE | 27 | 65 | 48 | 77 | 74 |
Figure S211. Get High-res Image Gene #66: 'del_21q11.2' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D66V7.png)
P value = 7.89e-05 (Fisher's exact test), Q value = 0.05
Table S212. Gene #66: 'del_21q11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 44(21Q11.2) MUTATED | 52 | 15 | 65 |
DEL PEAK 44(21Q11.2) WILD-TYPE | 112 | 83 | 96 |
Figure S212. Get High-res Image Gene #66: 'del_21q11.2' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D66V8.png)
P value = 0.000102 (Fisher's exact test), Q value = 0.064
Table S213. Gene #66: 'del_21q11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 44(21Q11.2) MUTATED | 35 | 11 | 22 |
DEL PEAK 44(21Q11.2) WILD-TYPE | 44 | 67 | 41 |
Figure S213. Get High-res Image Gene #66: 'del_21q11.2' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D66V11.png)
P value = 0.000134 (Fisher's exact test), Q value = 0.082
Table S214. Gene #67: 'del_22q13.32' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 56 | 43 | 47 |
DEL PEAK 45(22Q13.32) MUTATED | 26 | 6 | 25 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 30 | 37 | 22 |
Figure S214. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
![](D67V2.png)
P value = 8.41e-18 (Fisher's exact test), Q value = 6.5e-15
Table S215. Gene #67: 'del_22q13.32' versus Molecular Subtype #3: 'CN_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 171 | 195 | 61 |
DEL PEAK 45(22Q13.32) MUTATED | 102 | 33 | 14 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 69 | 162 | 47 |
Figure S215. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #3: 'CN_CNMF'
![](D67V3.png)
P value = 7.2e-07 (Chi-square test), Q value = 0.00049
Table S216. Gene #67: 'del_22q13.32' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
---|---|---|---|---|---|
ALL | 33 | 113 | 71 | 90 | 116 |
DEL PEAK 45(22Q13.32) MUTATED | 8 | 51 | 28 | 10 | 51 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 25 | 62 | 43 | 80 | 65 |
Figure S216. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
![](D67V7.png)
P value = 2.76e-07 (Fisher's exact test), Q value = 0.00019
Table S217. Gene #67: 'del_22q13.32' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 164 | 98 | 161 |
DEL PEAK 45(22Q13.32) MUTATED | 64 | 13 | 71 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 100 | 85 | 90 |
Figure S217. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
![](D67V8.png)
P value = 3.42e-06 (Fisher's exact test), Q value = 0.0023
Table S218. Gene #67: 'del_22q13.32' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
---|---|---|---|
ALL | 79 | 78 | 63 |
DEL PEAK 45(22Q13.32) MUTATED | 35 | 9 | 26 |
DEL PEAK 45(22Q13.32) WILD-TYPE | 44 | 69 | 37 |
Figure S218. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
![](D67V11.png)
-
Copy number data file = transformed.cor.cli.txt
-
Molecular subtype file = COAD-TP.transferedmergedcluster.txt
-
Number of patients = 427
-
Number of significantly focal cnvs = 67
-
Number of molecular subtypes = 12
-
Exclude genes that fewer than K tumors have alterations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multi-class clinical features (nominal or ordinal), Chi-square tests (Greenwood and Nikulin 1996) were used to estimate the P values using the 'chisq.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.
In addition to the links below, the full results of the analysis summarized in this report can also be downloaded programmatically using firehose_get, or interactively from either the Broad GDAC website or TCGA Data Coordination Center Portal.