CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Kidney Chromophobe (Primary solid tumor)
16 April 2014
|
analyses__2014_04_16
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C1CC0Z9W
Overview
Introduction
Summary
There are 3881 mutations identified by MuTect and 200 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-KL-8323-01A-21D-2310-10 | NM_000314.4_F195S | 0.16 | 0 | 0.05 |
| TCGA-KL-8324-01A-11D-2310-10 | NM_001126112.1_Y220C | 0.018 | 0 | 0.05 |
| TCGA-KL-8324-01A-11D-2310-10 | NM_001126112.1_P190L | 0.034 | 0 | 0.05 |
| TCGA-KL-8324-01A-11D-2310-10 | NM_000051.3_T2853M | 0.14 | 0 | 0.05 |
| TCGA-KL-8329-01A-11D-2310-10 | NM_001126112.1_Y205C | 0.012 | 0 | 0.05 |
Methods & Data
Copyright © 2014
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.