CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Ovarian Serous Cystadenocarcinoma (Primary solid tumor)
16 April 2014
|
analyses__2014_04_16
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C1ZP44S4
Overview
Introduction
Summary
There are 90 mutations identified by MuTect and 1 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-23-1120-01 | NM_001004318.2_A332D | 0.31 | 0.002 | 0.2 |
| TCGA-25-1326-01 | NM_018897.2_D136H | 0.36 | 0.008 | 0.35 |
| TCGA-25-2396-01 | NM_001020.4_R146P | 0.4 | 0.014 | 0.35 |
| TCGA-25-2398-01 | ENST00000222107_A538T | 0.4 | 0.015 | 0.35 |
| TCGA-24-2260-01 | NM_018940.2_A523T | 0.44 | 0.033 | 0.55 |
Methods & Data
Copyright © 2014
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.