Clinical Features	CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	70 (23%)	229	0.095975	1	0.77217	1	0.89374	1	0.67001	1	0.16815	1	0.28187	1	0.7115	1	0.59561	1	0.87237	1	0.78144	1
1q gain	136 (45%)	163	1.3396e-17	1.06e-14	0.29672	1	0.2834	1	0.77157	1	0.0097823	1	0.06447	1	0.27343	1	0.11607	1	0.04697	1	0.055076	1
2p gain	58 (19%)	241	0.00042423	0.322	0.61772	1	0.62517	1	0.89443	1	0.019079	1	0.00042106	0.32	0.013817	1	0.00018849	0.143	0.015598	1	0.0007736	0.582
2q gain	56 (19%)	243	1.4899e-05	0.0115	1	1	0.7476	1	0.26261	1	0.0013058	0.973	0.0012962	0.967	0.0012899	0.964	1.2522e-05	0.00964	0.0012144	0.91	0.00012662	0.0966
3p gain	48 (16%)	251	0.65352	1	0.22694	1	0.040644	1	0.049709	1	0.29714	1	0.38475	1	0.97374	1	0.69754	1	0.91677	1	0.37252	1
3q gain	58 (19%)	241	0.27199	1	0.56657	1	0.019536	1	0.048615	1	0.028887	1	0.16287	1	0.85686	1	0.63876	1	0.76345	1	0.76422	1
4p gain	44 (15%)	255	0.010452	1	0.15204	1	0.3047	1	0.2136	1	0.69183	1	0.88894	1	0.21004	1	0.079965	1	0.094323	1	0.12677	1
4q gain	37 (12%)	262	0.02009	1	0.08673	1	0.26056	1	0.41575	1	0.61239	1	0.67552	1	0.27982	1	0.18864	1	0.218	1	0.45123	1
5p gain	58 (19%)	241	0.013323	1	0.22231	1	0.88645	1	0.77245	1	0.16988	1	0.59448	1	0.054013	1	0.28621	1	0.13491	1	0.21734	1
5q gain	36 (12%)	263	0.051359	1	0.17756	1	0.40432	1	0.46176	1	0.78154	1	0.49888	1	0.029773	1	0.25615	1	0.11147	1	0.045981	1
6p gain	117 (39%)	182	6.4652e-08	5.07e-05	0.0013827	1	0.83889	1	0.1941	1	0.6659	1	0.19959	1	0.016588	1	0.00044613	0.338	0.068716	1	0.00047933	0.362
6q gain	39 (13%)	260	0.022311	1	0.11898	1	0.89916	1	0.43745	1	1	1	0.90664	1	0.16138	1	0.089477	1	0.4704	1	0.16064	1
7p gain	161 (54%)	138	7.1912e-06	0.00557	0.91252	1	0.45491	1	0.65362	1	0.073876	1	0.42377	1	0.61978	1	0.66383	1	0.77439	1	0.84593	1
7q gain	159 (53%)	140	1.6064e-06	0.00125	0.79927	1	0.68926	1	0.79446	1	0.017173	1	0.089069	1	0.46736	1	0.15788	1	0.66019	1	0.4487	1
8p gain	99 (33%)	200	2.3249e-05	0.0179	0.06571	1	0.61453	1	0.79573	1	0.0061648	1	0.23643	1	0.16387	1	0.76001	1	0.069067	1	0.14963	1
8q gain	141 (47%)	158	1.5038e-06	0.00117	0.0011423	0.858	0.64026	1	0.68721	1	0.0015761	1	0.20507	1	0.14279	1	0.73236	1	0.10439	1	0.081415	1
9p gain	15 (5%)	284	0.34512	1	0.27996	1	0.37548	1	0.76786	1	0.45082	1	0.69995	1	1	1	0.3084	1	0.73701	1	0.35015	1
9q gain	20 (7%)	279	0.18081	1	0.68556	1	0.13535	1	0.50935	1	0.57046	1	0.92435	1	0.87509	1	0.56635	1	0.69895	1	0.62573	1
10p gain	10 (3%)	289	0.88869	1	1	1	0.86633	1	0.84556	1	0.66177	1	0.70129	1	0.83643	1	0.77973	1	1	1	0.49961	1
11p gain	30 (10%)	269	0.013785	1	0.60307	1	0.086466	1	0.031415	1	0.0046521	1	0.31259	1	0.098611	1	0.016992	1	0.12007	1	0.09291	1
11q gain	26 (9%)	273	0.00068123	0.514	0.41517	1	0.075836	1	0.0040881	1	0.010026	1	0.28748	1	0.13817	1	0.0098072	1	0.1211	1	0.0609	1
12p gain	50 (17%)	249	0.0047409	1	0.32287	1	0.3674	1	0.33511	1	0.024281	1	0.064189	1	0.92455	1	0.60044	1	0.74434	1	0.85054	1
12q gain	33 (11%)	266	0.065045	1	0.69309	1	0.60235	1	0.050175	1	0.54999	1	0.7251	1	0.89299	1	0.52199	1	0.76554	1	0.74262	1
13q gain	75 (25%)	224	4.6036e-09	3.61e-06	7.7332e-06	0.00597	0.50346	1	0.43567	1	0.0013254	0.985	0.0013159	0.979	0.6688	1	0.96554	1	0.60254	1	0.97245	1
14q gain	32 (11%)	267	0.3158	1	0.25456	1	0.49723	1	0.10355	1	0.87839	1	0.31253	1	0.05345	1	0.628	1	0.79425	1	0.93208	1
15q gain	69 (23%)	230	3.2022e-06	0.00248	0.38387	1	0.82427	1	0.91161	1	0.068432	1	0.045364	1	0.22765	1	0.060487	1	0.22094	1	0.071859	1
16p gain	41 (14%)	258	0.09143	1	0.0095099	1	1	1	0.87992	1	0.00010195	0.0779	0.0054083	1	0.037341	1	0.17826	1	0.028153	1	0.079285	1
16q gain	35 (12%)	264	0.27899	1	0.026946	1	0.26427	1	0.71124	1	0.00013798	0.105	0.0012626	0.944	0.057869	1	0.11572	1	0.0765	1	0.069444	1
17p gain	34 (11%)	265	0.0076359	1	0.0045635	1	0.59534	1	0.61817	1	0.38549	1	0.20565	1	0.40063	1	0.12287	1	0.73658	1	0.18309	1
17q gain	59 (20%)	240	0.063336	1	0.075159	1	0.080773	1	0.07131	1	0.62017	1	0.087968	1	0.15279	1	0.37275	1	0.096054	1	0.012465	1
18p gain	48 (16%)	251	0.044081	1	0.98093	1	0.20754	1	0.51021	1	0.12499	1	0.91176	1	0.51403	1	0.39577	1	0.36831	1	0.50881	1
18q gain	39 (13%)	260	0.023613	1	1	1	0.39689	1	0.7927	1	0.34806	1	0.92116	1	0.74004	1	0.79305	1	0.37086	1	0.66943	1
19p gain	43 (14%)	256	0.257	1	0.049146	1	0.25474	1	0.4768	1	0.0055516	1	0.0016961	1	0.87757	1	0.40483	1	0.71285	1	0.64263	1
19q gain	44 (15%)	255	0.13013	1	0.023806	1	0.29761	1	0.89395	1	0.00073059	0.55	0.00061779	0.466	0.62231	1	0.3207	1	0.50195	1	0.696	1
20p gain	124 (41%)	175	5.6722e-07	0.000442	0.010436	1	0.83839	1	0.81577	1	5.9958e-05	0.0459	0.0033702	1	0.13628	1	0.17923	1	0.090834	1	0.39188	1
20q gain	147 (49%)	152	8.7268e-07	0.00068	0.054492	1	0.93326	1	0.96683	1	0.0011635	0.873	0.026499	1	0.75582	1	0.27317	1	0.1285	1	0.46203	1
21q gain	54 (18%)	245	0.42408	1	0.07641	1	0.87597	1	0.78061	1	0.37992	1	0.39307	1	0.37369	1	1	1	0.42998	1	0.85243	1
22q gain	107 (36%)	192	0.0051651	1	0.39563	1	0.90271	1	0.72646	1	0.095604	1	0.14143	1	0.32421	1	0.87199	1	0.26963	1	0.85694	1
xq gain	32 (11%)	267	0.0080374	1	0.026658	1	0.67009	1	0.78703	1	0.1164	1	0.13764	1	0.7087	1	0.73381	1	0.87732	1	0.47589	1
1p loss	36 (12%)	263	0.25242	1	0.005895	1	0.37555	1	0.036057	1	0.053113	1	0.45514	1	0.15316	1	0.45113	1	0.2688	1	0.27819	1
1q loss	20 (7%)	279	0.10714	1	0.19054	1	0.9685	1	0.44772	1	0.24145	1	1	1	0.1131	1	0.24395	1	0.16386	1	0.27304	1
2p loss	38 (13%)	261	0.19845	1	0.3497	1	0.049475	1	0.0069209	1	0.54809	1	0.09115	1	0.0042821	1	0.034029	1	0.0054601	1	0.12523	1
2q loss	39 (13%)	260	0.035868	1	0.085249	1	0.012921	1	0.0041164	1	0.1566	1	0.16957	1	0.0034655	1	0.052623	1	0.0065893	1	0.17088	1
3p loss	48 (16%)	251	0.27426	1	0.42111	1	0.48599	1	0.68125	1	0.064954	1	0.080753	1	0.28536	1	0.37905	1	0.054196	1	0.025715	1
3q loss	37 (12%)	262	0.30765	1	0.21835	1	0.37955	1	0.53794	1	0.33041	1	0.36004	1	0.59419	1	0.66462	1	0.36131	1	0.43956	1
4p loss	64 (21%)	235	0.7772	1	0.21712	1	0.35245	1	0.86372	1	0.55439	1	0.14451	1	0.11374	1	0.018958	1	0.037909	1	0.075244	1
4q loss	66 (22%)	233	0.40435	1	0.058795	1	0.48124	1	0.72293	1	0.22879	1	0.019512	1	0.013433	1	0.0032051	1	0.006638	1	0.020113	1
5p loss	66 (22%)	233	0.21524	1	0.20395	1	0.77999	1	0.85783	1	0.79096	1	0.97925	1	0.74645	1	0.85044	1	0.9322	1	0.44888	1
5q loss	84 (28%)	215	0.016913	1	0.01411	1	0.44311	1	0.8555	1	0.61394	1	0.47322	1	0.97553	1	0.78959	1	0.79708	1	0.17041	1
6p loss	56 (19%)	243	0.0021718	1	0.78259	1	0.89043	1	0.36093	1	0.0089064	1	0.19675	1	0.14421	1	0.035997	1	0.12933	1	0.050382	1
6q loss	146 (49%)	153	3.1437e-07	0.000246	0.060032	1	0.99131	1	0.21861	1	0.0042573	1	0.19063	1	0.4209	1	0.51069	1	0.88607	1	0.18904	1
7p loss	16 (5%)	283	0.79908	1	0.13887	1	0.094847	1	0.19434	1	0.88818	1	0.33004	1	0.53678	1	0.41282	1	0.69022	1	0.86902	1
7q loss	15 (5%)	284	0.77597	1	0.060211	1	0.33811	1	0.60719	1	0.31067	1	0.60521	1	0.40731	1	0.92057	1	0.5739	1	0.93326	1
8p loss	53 (18%)	246	0.69831	1	0.93974	1	0.087182	1	0.44963	1	0.40644	1	0.91165	1	0.53044	1	0.21689	1	0.40904	1	0.51867	1
8q loss	21 (7%)	278	0.36691	1	0.13922	1	0.31196	1	0.20108	1	0.60182	1	0.35339	1	0.40292	1	0.72299	1	0.24135	1	0.37658	1
9p loss	197 (66%)	102	0.029756	1	0.061241	1	0.63579	1	0.85815	1	0.0015374	1	0.10021	1	0.68848	1	0.28925	1	0.62534	1	0.63823	1
9q loss	154 (52%)	145	0.85291	1	0.097442	1	0.96685	1	0.45763	1	0.043653	1	0.27728	1	0.29753	1	0.5637	1	0.82782	1	0.56288	1
10p loss	167 (56%)	132	1.1299e-09	8.89e-07	0.015374	1	0.89422	1	0.34449	1	4.3561e-05	0.0334	0.0042699	1	0.54259	1	0.84141	1	0.68548	1	0.2891	1
10q loss	185 (62%)	114	1.766e-09	1.39e-06	0.018975	1	0.90324	1	0.2073	1	1.2401e-05	0.00956	0.00045883	0.347	0.95921	1	0.91669	1	0.82516	1	0.60168	1
11p loss	102 (34%)	197	3.4896e-06	0.0027	0.038838	1	0.57503	1	0.59122	1	0.12975	1	0.60779	1	0.4243	1	0.32025	1	0.20874	1	0.21008	1
11q loss	117 (39%)	182	7.8464e-08	6.14e-05	0.15972	1	0.95472	1	0.623	1	0.068876	1	0.51141	1	0.71593	1	0.33552	1	0.89286	1	0.23842	1
12p loss	46 (15%)	253	0.014896	1	0.12143	1	0.74719	1	0.14507	1	0.038512	1	0.82158	1	0.82438	1	0.87157	1	0.58648	1	0.76213	1
12q loss	52 (17%)	247	0.0046014	1	0.098213	1	0.98843	1	0.37026	1	0.049936	1	0.85465	1	0.58736	1	0.5473	1	0.92765	1	0.73828	1
13q loss	65 (22%)	234	7.5059e-06	0.0058	0.012929	1	0.039917	1	0.52317	1	0.7886	1	0.1477	1	0.57357	1	0.1422	1	0.62284	1	0.19399	1
14q loss	93 (31%)	206	1.0955e-07	8.57e-05	0.7802	1	0.40817	1	0.41724	1	0.002144	1	0.50255	1	0.59925	1	0.96339	1	0.54591	1	0.83445	1
15q loss	42 (14%)	257	0.0020045	1	0.24824	1	0.12994	1	0.13161	1	0.17376	1	0.19512	1	0.73031	1	0.67927	1	0.47981	1	0.20798	1
16p loss	58 (19%)	241	0.11188	1	0.11634	1	0.047349	1	0.51082	1	0.021949	1	0.16991	1	0.12422	1	0.25502	1	0.26157	1	0.30539	1
16q loss	87 (29%)	212	0.053471	1	0.28682	1	0.011444	1	0.8071	1	0.025993	1	0.053735	1	0.079961	1	0.085574	1	0.22802	1	0.06067	1
17p loss	101 (34%)	198	0.70762	1	0.12359	1	0.74856	1	0.19867	1	0.24628	1	0.2409	1	0.97549	1	0.37652	1	0.66601	1	0.55086	1
17q loss	50 (17%)	249	0.6104	1	0.42056	1	0.17459	1	0.053903	1	0.9377	1	0.83537	1	0.20689	1	0.4982	1	0.64053	1	0.18416	1
18p loss	86 (29%)	213	0.30466	1	0.47597	1	0.37072	1	0.75179	1	0.013577	1	0.33854	1	1	1	0.46793	1	0.6602	1	0.33124	1
18q loss	82 (27%)	217	0.08721	1	0.60305	1	0.39568	1	0.75004	1	0.4248	1	0.78531	1	0.78214	1	0.48154	1	0.90305	1	0.5145	1
19p loss	62 (21%)	237	0.0043325	1	0.20422	1	0.75869	1	0.1864	1	0.056929	1	0.93954	1	0.3205	1	0.56981	1	0.28672	1	0.66426	1
19q loss	60 (20%)	239	0.006806	1	0.078462	1	0.9672	1	0.078947	1	0.12443	1	0.54789	1	0.53329	1	0.52236	1	0.62186	1	0.55425	1
20p loss	18 (6%)	281	0.45527	1	0.8073	1	0.2356	1	0.40309	1	0.58012	1	0.21872	1	0.13131	1	0.57249	1	0.24573	1	0.32981	1
20q loss	7 (2%)	292	0.49797	1	0.34607	1	NA	NA	NA	NA	0.13592	1	0.0031388	1	0.52917	1	0.79668	1	0.33289	1	0.58167	1
21q loss	58 (19%)	241	0.14801	1	0.42879	1	0.46993	1	0.63182	1	0.4919	1	0.18467	1	0.16748	1	0.36774	1	0.10356	1	0.26725	1
22q loss	32 (11%)	267	0.18261	1	0.24546	1	0.95371	1	0.91544	1	0.8067	1	0.7251	1	0.48218	1	0.8435	1	0.76887	1	0.74609	1
xq loss	74 (25%)	225	0.024114	1	2.378e-05	0.0182	0.30127	1	0.39655	1	0.0022434	1	0.039792	1	0.0090584	1	0.46554	1	0.10064	1	0.83924	1