CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Thyroid Adenocarcinoma (Primary solid tumor)
16 April 2014
|
analyses__2014_04_16
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C1183561
Overview
Introduction
Summary
There are 4376 mutations identified by MuTect and 801 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-BJ-A0YZ-01A-11D-A10S-08 | ENST00000396636_C532S | 0.32 | 0.004 | 0.05 |
| TCGA-BJ-A0Z0-01A-11D-A10S-08 | NM_005921.1_L1354V | 0.21 | 0 | 0.05 |
| TCGA-BJ-A0Z2-01A-11D-A10S-08 | NM_005343.2_Q61R | 0.26 | 0.001 | 0.05 |
| TCGA-BJ-A0Z2-01A-11D-A10S-08 | NM_002742.2_F781L | 0.21 | 0 | 0.05 |
| TCGA-BJ-A0Z2-01A-11D-A10S-08 | NM_004103.3_G491D | 0.25 | 0.001 | 0.05 |
Methods & Data
Copyright © 2014
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.