CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations)
Uterine Carcinosarcoma (Primary solid tumor)
16 April 2014
|
analyses__2014_04_16
Maintainer Information
Citation Information
Maintained by Spring Yingchun Liu
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
CHASM 1.0.5 (Cancer-Specific High-throughput Annotation of Somatic Mutations).
Broad Institute of MIT and Harvard.
doi:10.7908/C16H4G46
Overview
Introduction
Summary
There are 6270 mutations identified by MuTect and 445 mutations with significant functional impact at BHFDR <= 0.25.
Results
Top Mutations
Table 1.
Get Full Table
Top mutations with significant funcational impact.
MutationID: mutation seen in sample.
Mutation: mutation seen in gene and AA variant.
CHASM: CHASM score.
BHFDR: Benjamini-Hochberg False Discovery Rate.
| MutationID | Mutation | CHASM | PValue | BHFDR |
|---|---|---|---|---|
| TCGA-N5-A4R8-01A-11D-A28R-08 | NM_006218.2_E545K | 0.024 | 0 | 0.05 |
| TCGA-N5-A4RA-01A-11D-A28R-08 | NM_198274.3_G194D | 0.16 | 0 | 0.05 |
| TCGA-N5-A4RD-01A-11D-A28R-08 | NM_001126112.1_R248Q | 0.034 | 0 | 0.05 |
| TCGA-N5-A4RD-01A-11D-A28R-08 | NM_033632.2_R465H | 0.25 | 0.001 | 0.05 |
| TCGA-N5-A4RF-01A-11D-A28R-08 | NM_006218.2_G106V | 0.062 | 0 | 0.05 |
Methods & Data
Copyright © 2014
Broad Institute TCGA GDAC as part of the TCGA Research Network.
All rights reserved.