Correlation between gene mutation status and molecular subtypes
Overview
Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 101 genes and 8 molecular subtypes across 202 patients, 8 significant findings detected with P value < 0.05 and Q value < 0.25.

  • TP53 mutation correlated to 'MRNASEQ_CNMF' and 'MIRSEQ_CHIERARCHICAL'.

  • CTNNB1 mutation correlated to 'METHLYATION_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • BAP1 mutation correlated to 'MRNASEQ_CNMF'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between mutation status of 101 genes and 8 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 8 significant findings detected.

Clinical
Features 		CN
CNMF 		METHLYATION
CNMF 		MRNASEQ
CNMF 		MRNASEQ
CHIERARCHICAL 		MIRSEQ
CNMF 		MIRSEQ
CHIERARCHICAL 		MIRSEQ
MATURE
CNMF 		MIRSEQ
MATURE
CHIERARCHICAL
nMutated (%) nWild-Type Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test
CTNNB1 57 (28%) 145 0.00228
(1.00) 		0.00017
(0.136) 		1e-05
(0.00806) 		1e-05
(0.00806) 		0.218
(1.00) 		1e-05
(0.00806) 		0.00059
(0.471) 		1e-05
(0.00806)
TP53 65 (32%) 137 0.058
(1.00) 		0.451
(1.00) 		0.00025
(0.2) 		0.979
(1.00) 		0.00898
(1.00) 		1e-05
(0.00806) 		0.0296
(1.00) 		0.00238
(1.00)
BAP1 11 (5%) 191 0.732
(1.00) 		0.00168
(1.00) 		5e-05
(0.04) 		0.00095
(0.757) 		0.0212
(1.00) 		0.00099
(0.788) 		0.00323
(1.00) 		0.0332
(1.00)
ARID1A 25 (12%) 177 0.729
(1.00) 		0.891
(1.00) 		0.191
(1.00) 		0.41
(1.00) 		0.353
(1.00) 		0.0213
(1.00) 		0.452
(1.00) 		0.511
(1.00)
RB1 18 (9%) 184 0.0217
(1.00) 		0.00224
(1.00) 		0.0394
(1.00) 		0.0339
(1.00) 		0.34
(1.00) 		0.522
(1.00) 		0.0865
(1.00) 		0.311
(1.00)
AXIN1 12 (6%) 190 0.067
(1.00) 		0.692
(1.00) 		0.132
(1.00) 		0.0669
(1.00) 		0.144
(1.00) 		0.0475
(1.00) 		0.0116
(1.00) 		0.0764
(1.00)
KRTAP5-11 5 (2%) 197 0.534
(1.00) 		0.859
(1.00) 		0.489
(1.00) 		0.843
(1.00) 		0.451
(1.00) 		0.884
(1.00) 		0.657
(1.00) 		0.791
(1.00)
AHCTF1 13 (6%) 189 0.875
(1.00) 		0.614
(1.00) 		0.77
(1.00) 		0.329
(1.00) 		0.578
(1.00) 		0.102
(1.00) 		0.779
(1.00) 		0.558
(1.00)
GPATCH4 11 (5%) 191 0.0405
(1.00) 		0.855
(1.00) 		0.585
(1.00) 		0.635
(1.00) 		0.177
(1.00) 		0.122
(1.00) 		0.0436
(1.00) 		0.0617
(1.00)
CD207 8 (4%) 194 0.305
(1.00) 		0.185
(1.00) 		0.432
(1.00) 		0.691
(1.00) 		0.529
(1.00) 		0.568
(1.00) 		0.82
(1.00) 		0.557
(1.00)
EEF1A1 9 (4%) 193 1
(1.00) 		0.377
(1.00) 		0.173
(1.00) 		0.0256
(1.00) 		0.754
(1.00) 		0.589
(1.00) 		0.551
(1.00) 		0.606
(1.00)
CHIT1 8 (4%) 194 0.42
(1.00) 		1
(1.00) 		0.721
(1.00) 		0.715
(1.00) 		0.468
(1.00) 		0.418
(1.00) 		0.503
(1.00) 		0.85
(1.00)
PPIAL4G 7 (3%) 195 0.794
(1.00) 		0.324
(1.00) 		0.283
(1.00) 		0.269
(1.00) 		0.228
(1.00) 		0.123
(1.00) 		0.165
(1.00) 		0.111
(1.00)
ALB 24 (12%) 178 0.0362
(1.00) 		0.414
(1.00) 		0.621
(1.00) 		0.631
(1.00) 		0.881
(1.00) 		0.907
(1.00) 		0.327
(1.00) 		0.638
(1.00)
PABPC1 8 (4%) 194 0.274
(1.00) 		1
(1.00) 		0.322
(1.00) 		0.459
(1.00) 		0.668
(1.00) 		0.841
(1.00) 		0.933
(1.00) 		0.979
(1.00)
TREML2 6 (3%) 196 0.628
(1.00) 		1
(1.00) 		0.175
(1.00) 		0.0906
(1.00) 		0.449
(1.00) 		0.0316
(1.00) 		0.492
(1.00) 		0.0324
(1.00)
PRH2 6 (3%) 196 0.661
(1.00) 		0.874
(1.00) 		0.448
(1.00) 		0.866
(1.00) 		0.769
(1.00) 		0.859
(1.00) 		0.39
(1.00) 		0.971
(1.00)
MUC17 28 (14%) 174 0.865
(1.00) 		0.87
(1.00) 		0.663
(1.00) 		0.734
(1.00) 		0.635
(1.00) 		0.552
(1.00) 		0.84
(1.00) 		0.502
(1.00)
AZIN1 13 (6%) 189 0.318
(1.00) 		0.44
(1.00) 		0.0375
(1.00) 		0.388
(1.00) 		0.0276
(1.00) 		0.0152
(1.00) 		0.108
(1.00) 		0.00501
(1.00)
NBPF3 7 (3%) 195 0.267
(1.00) 		0.426
(1.00) 		0.0353
(1.00) 		0.864
(1.00) 		0.796
(1.00) 		0.587
(1.00) 		0.542
(1.00) 		0.825
(1.00)
BCLAF1 14 (7%) 188 0.829
(1.00) 		0.291
(1.00) 		0.679
(1.00) 		1
(1.00) 		0.883
(1.00) 		0.823
(1.00) 		0.535
(1.00) 		0.908
(1.00)
SCRN3 9 (4%) 193 0.346
(1.00) 		0.199
(1.00) 		0.731
(1.00) 		0.493
(1.00) 		0.688
(1.00) 		0.589
(1.00) 		0.33
(1.00) 		0.61
(1.00)
MUC6 25 (12%) 177 0.12
(1.00) 		0.0854
(1.00) 		0.532
(1.00) 		0.923
(1.00) 		0.588
(1.00) 		0.234
(1.00) 		0.436
(1.00) 		0.307
(1.00)
UGT2B28 11 (5%) 191 0.302
(1.00) 		0.225
(1.00) 		0.14
(1.00) 		0.13
(1.00) 		0.146
(1.00) 		0.142
(1.00) 		0.693
(1.00) 		0.293
(1.00)
CDHR5 11 (5%) 191 0.055
(1.00) 		0.111
(1.00) 		0.96
(1.00) 		0.664
(1.00) 		0.789
(1.00) 		0.805
(1.00) 		0.839
(1.00) 		0.89
(1.00)
KCTD3 6 (3%) 196 0.024
(1.00) 		0.376
(1.00) 		0.755
(1.00) 		0.657
(1.00) 		0.508
(1.00) 		0.383
(1.00) 		0.348
(1.00) 		0.309
(1.00)
CDC27 14 (7%) 188 0.534
(1.00) 		0.291
(1.00) 		0.054
(1.00) 		0.00473
(1.00) 		0.114
(1.00) 		0.0196
(1.00) 		0.119
(1.00) 		0.0577
(1.00)
CR1 19 (9%) 183 0.954
(1.00) 		0.861
(1.00) 		0.508
(1.00) 		0.442
(1.00) 		0.296
(1.00) 		0.316
(1.00) 		0.547
(1.00) 		0.758
(1.00)
TCEAL6 4 (2%) 198 0.0383
(1.00) 		0.154
(1.00) 		0.0622
(1.00) 		0.786
(1.00) 		0.553
(1.00) 		0.274
(1.00) 		1
(1.00) 		0.38
(1.00)
LILRA6 11 (5%) 191 0.232
(1.00) 		0.208
(1.00) 		0.35
(1.00) 		0.0781
(1.00) 		0.117
(1.00) 		0.00605
(1.00) 		0.162
(1.00) 		0.0374
(1.00)
BIK 3 (1%) 199 0.351
(1.00) 		0.795
(1.00) 		0.716
(1.00) 		1
(1.00) 		0.253
(1.00) 		0.108
(1.00) 		0.226
(1.00) 		0.03
(1.00)
SRRM3 4 (2%) 198 0.0384
(1.00) 		0.155
(1.00) 		0.132
(1.00) 		0.315
(1.00) 		0.085
(1.00) 		0.0222
(1.00) 		0.868
(1.00) 		0.0301
(1.00)
MKI67 17 (8%) 185 1
(1.00) 		0.466
(1.00) 		0.553
(1.00) 		0.431
(1.00) 		0.948
(1.00) 		0.349
(1.00) 		0.168
(1.00) 		0.666
(1.00)
ALDH3B1 5 (2%) 197 0.0117
(1.00) 		0.074
(1.00) 		0.345
(1.00) 		1
(1.00) 		0.741
(1.00) 		0.407
(1.00) 		1
(1.00) 		0.538
(1.00)
POTEG 13 (6%) 189 0.0931
(1.00) 		0.472
(1.00) 		0.834
(1.00) 		0.419
(1.00) 		0.617
(1.00) 		0.327
(1.00) 		0.148
(1.00) 		0.337
(1.00)
ZNF658 8 (4%) 194 0.0114
(1.00) 		0.238
(1.00) 		0.437
(1.00) 		0.233
(1.00) 		1
(1.00) 		0.142
(1.00) 		0.8
(1.00) 		0.302
(1.00)
TCHH 22 (11%) 180 0.514
(1.00) 		0.0424
(1.00) 		0.658
(1.00) 		0.608
(1.00) 		1
(1.00) 		0.106
(1.00) 		0.844
(1.00) 		0.323
(1.00)
TMEM176A 4 (2%) 198 0.174
(1.00) 		0.154
(1.00) 		0.239
(1.00) 		1
(1.00) 		0.134
(1.00) 		0.682
(1.00) 		0.257
(1.00) 		0.935
(1.00)
RP1L1 21 (10%) 181 0.341
(1.00) 		0.061
(1.00) 		0.0109
(1.00) 		0.544
(1.00) 		0.67
(1.00) 		0.799
(1.00) 		0.329
(1.00) 		0.301
(1.00)
TSC2 15 (7%) 187 0.316
(1.00) 		0.0452
(1.00) 		0.472
(1.00) 		0.499
(1.00) 		0.837
(1.00) 		0.578
(1.00) 		0.604
(1.00) 		0.74
(1.00)
PRKDC 24 (12%) 178 0.887
(1.00) 		0.164
(1.00) 		0.625
(1.00) 		0.918
(1.00) 		1
(1.00) 		0.17
(1.00) 		0.689
(1.00) 		0.367
(1.00)
NRD1 11 (5%) 191 0.422
(1.00) 		0.924
(1.00) 		0.887
(1.00) 		0.177
(1.00) 		0.791
(1.00) 		0.144
(1.00) 		0.563
(1.00) 		0.0804
(1.00)
TAS2R20 4 (2%) 198 0.301
(1.00) 		0.278
(1.00) 		0.487
(1.00) 		0.0106
(1.00) 		0.836
(1.00) 		0.0829
(1.00) 		0.667
(1.00) 		0.539
(1.00)
PTEN 10 (5%) 192 0.188
(1.00) 		0.0982
(1.00) 		0.86
(1.00) 		0.824
(1.00) 		0.46
(1.00) 		0.829
(1.00) 		0.934
(1.00) 		0.81
(1.00)
CYFIP2 13 (6%) 189 0.766
(1.00) 		0.714
(1.00) 		0.657
(1.00) 		0.331
(1.00) 		0.186
(1.00) 		0.887
(1.00) 		0.311
(1.00) 		0.606
(1.00)
PRAMEF1 9 (4%) 193 1
(1.00) 		0.507
(1.00) 		0.285
(1.00) 		0.145
(1.00) 		0.579
(1.00) 		0.0206
(1.00) 		0.0642
(1.00) 		0.203
(1.00)
MST1 8 (4%) 194 0.421
(1.00) 		0.584
(1.00) 		0.636
(1.00) 		0.777
(1.00) 		0.819
(1.00) 		0.652
(1.00) 		0.965
(1.00) 		0.946
(1.00)
ZC3H7A 12 (6%) 190 0.258
(1.00) 		0.744
(1.00) 		0.71
(1.00) 		0.856
(1.00) 		0.243
(1.00) 		0.792
(1.00) 		0.252
(1.00) 		0.128
(1.00)
MLL3 30 (15%) 172 0.438
(1.00) 		0.494
(1.00) 		0.0177
(1.00) 		0.481
(1.00) 		0.907
(1.00) 		0.564
(1.00) 		0.149
(1.00) 		0.925
(1.00)
HNRNPCL1 11 (5%) 191 0.162
(1.00) 		0.925
(1.00) 		0.546
(1.00) 		0.761
(1.00) 		0.193
(1.00) 		0.327
(1.00) 		0.732
(1.00) 		0.848
(1.00)
TUBA3E 7 (3%) 195 0.795
(1.00) 		0.889
(1.00) 		0.122
(1.00) 		0.0658
(1.00) 		0.698
(1.00) 		0.00747
(1.00) 		0.219
(1.00) 		0.115
(1.00)
MUC21 16 (8%) 186 0.66
(1.00) 		1
(1.00) 		0.875
(1.00) 		0.439
(1.00) 		0.945
(1.00) 		0.734
(1.00) 		0.61
(1.00) 		0.662
(1.00)
HPS4 5 (2%) 197 0.175
(1.00) 		0.0566
(1.00) 		0.261
(1.00) 		0.105
(1.00) 		0.451
(1.00) 		0.239
(1.00) 		0.929
(1.00) 		0.885
(1.00)
OR2T4 14 (7%) 188 0.0162
(1.00) 		0.0546
(1.00) 		0.0532
(1.00) 		0.0128
(1.00) 		0.608
(1.00) 		0.215
(1.00) 		0.624
(1.00) 		0.167
(1.00)
SPDYE1 4 (2%) 198 0.235
(1.00) 		0.367
(1.00) 		0.491
(1.00) 		0.144
(1.00) 		0.453
(1.00) 		0.0425
(1.00) 		0.727
(1.00) 		0.454
(1.00)
COG2 6 (3%) 196 0.289
(1.00) 		0.118
(1.00) 		0.551
(1.00) 		0.844
(1.00) 		0.0742
(1.00) 		0.302
(1.00) 		0.523
(1.00) 		0.357
(1.00)
SEC63 10 (5%) 192 0.0535
(1.00) 		0.0886
(1.00) 		0.219
(1.00) 		0.713
(1.00) 		0.55
(1.00) 		0.16
(1.00) 		0.906
(1.00) 		0.934
(1.00)
LILRA3 5 (2%) 197 0.234
(1.00) 		0.213
(1.00) 		0.0226
(1.00) 		0.00464
(1.00) 		0.452
(1.00) 		0.00899
(1.00) 		0.139
(1.00) 		0.189
(1.00)
CYP2A6 6 (3%) 196 1
(1.00) 		0.172
(1.00) 		0.838
(1.00) 		0.0741
(1.00) 		1
(1.00) 		0.678
(1.00) 		0.562
(1.00) 		0.512
(1.00)
ZC3H11A 6 (3%) 196 0.373
(1.00) 		0.324
(1.00) 		0.216
(1.00) 		0.296
(1.00) 		0.883
(1.00) 		0.239
(1.00) 		0.862
(1.00) 		0.186
(1.00)
LCE4A 10 (5%) 192 0.222
(1.00) 		0.549
(1.00) 		0.453
(1.00) 		1
(1.00) 		0.844
(1.00) 		0.672
(1.00) 		0.0521
(1.00) 		0.934
(1.00)
ATXN3 6 (3%) 196 0.138
(1.00) 		0.33
(1.00) 		0.873
(1.00) 		0.866
(1.00) 		0.445
(1.00) 		0.887
(1.00) 		0.205
(1.00) 		0.837
(1.00)
GTF2IRD2B 5 (2%) 197 0.0648
(1.00) 		0.0728
(1.00) 		0.133
(1.00) 		0.315
(1.00) 		0.296
(1.00) 		0.113
(1.00) 		0.962
(1.00) 		0.159
(1.00)
QRICH2 19 (9%) 183 0.295
(1.00) 		0.352
(1.00) 		0.199
(1.00) 		0.214
(1.00) 		0.532
(1.00) 		0.173
(1.00) 		0.111
(1.00) 		0.465
(1.00)
PLAU 6 (3%) 196 0.507
(1.00) 		0.665
(1.00) 		0.31
(1.00) 		1
(1.00) 		0.882
(1.00) 		0.764
(1.00) 		0.883
(1.00) 		0.915
(1.00)
MAPKAPK2 4 (2%) 198 0.454
(1.00) 		0.689
(1.00) 		0.803
(1.00) 		1
(1.00) 		0.454
(1.00) 		0.769
(1.00) 		0.83
(1.00) 		0.146
(1.00)
NAP1L1 6 (3%) 196 0.505
(1.00) 		1
(1.00) 		0.134
(1.00) 		0.672
(1.00) 		0.339
(1.00) 		0.859
(1.00) 		0.728
(1.00) 		0.56
(1.00)
FAM118A 4 (2%) 198 0.682
(1.00) 		0.817
(1.00) 		0.532
(1.00) 		0.675
(1.00) 		0.369
(1.00) 		0.599
(1.00) 		0.217
(1.00) 		1
(1.00)
SLC7A6OS 4 (2%) 198 1
(1.00) 		1
(1.00) 		0.0375
(1.00) 		0.41
(1.00) 		0.291
(1.00) 		0.725
(1.00) 		0.389
(1.00) 		0.573
(1.00)
NBPF10 12 (6%) 190 0.204
(1.00) 		0.745
(1.00) 		1
(1.00) 		1
(1.00) 		0.558
(1.00) 		0.505
(1.00) 		0.526
(1.00) 		0.764
(1.00)
ZXDC 6 (3%) 196 1
(1.00) 		0.205
(1.00) 		0.236
(1.00) 		0.422
(1.00) 		0.00862
(1.00) 		0.0371
(1.00) 		0.124
(1.00) 		0.0647
(1.00)
TAS2R30 8 (4%) 194 1
(1.00) 		0.898
(1.00) 		0.536
(1.00) 		0.898
(1.00) 		0.742
(1.00) 		1
(1.00) 		0.152
(1.00) 		0.978
(1.00)
KRTAP10-2 7 (3%) 195 0.38
(1.00) 		0.702
(1.00) 		0.317
(1.00) 		0.269
(1.00) 		0.897
(1.00) 		0.0013
(1.00) 		0.103
(1.00) 		0.139
(1.00)
PPA2 4 (2%) 198 0.684
(1.00) 		0.581
(1.00) 		0.801
(1.00) 		1
(1.00) 		1
(1.00) 		0.6
(1.00) 		0.284
(1.00) 		0.454
(1.00)
SEPT2 7 (3%) 195 0.265
(1.00) 		0.285
(1.00) 		0.503
(1.00) 		0.295
(1.00) 		0.698
(1.00) 		0.585
(1.00) 		0.816
(1.00) 		0.467
(1.00)
DRD3 5 (2%) 197 0.627
(1.00) 		0.0726
(1.00) 		0.0385
(1.00) 		0.531
(1.00) 		0.00703
(1.00) 		0.314
(1.00) 		0.134
(1.00) 		0.356
(1.00)
PSRC1 4 (2%) 198 0.562
(1.00) 		0.369
(1.00) 		0.0418
(1.00) 		0.682
(1.00) 		0.319
(1.00) 		0.935
(1.00)
KRTAP10-9 3 (1%) 199 0.472
(1.00) 		0.612
(1.00) 		0.349
(1.00) 		0.0915
(1.00) 		1
(1.00) 		0.0432
(1.00) 		0.431
(1.00) 		0.629
(1.00)
SPATA12 6 (3%) 196 0.878
(1.00) 		1
(1.00) 		0.855
(1.00) 		1
(1.00) 		0.658
(1.00) 		0.859
(1.00) 		0.845
(1.00) 		0.68
(1.00)
GPR112 15 (7%) 187 0.528
(1.00) 		0.451
(1.00) 		0.533
(1.00) 		0.477
(1.00) 		0.488
(1.00) 		0.393
(1.00) 		0.162
(1.00) 		0.181
(1.00)
CLTCL1 16 (8%) 186 0.355
(1.00) 		0.377
(1.00) 		0.709
(1.00) 		0.6
(1.00) 		0.745
(1.00) 		0.0843
(1.00) 		0.826
(1.00) 		0.291
(1.00)
OR2A14 5 (2%) 197 0.626
(1.00) 		0.215
(1.00) 		0.805
(1.00) 		1
(1.00) 		1
(1.00) 		0.363
(1.00) 		0.587
(1.00) 		0.536
(1.00)
OR4C16 7 (3%) 195 0.0925
(1.00) 		0.127
(1.00) 		0.0197
(1.00) 		0.0336
(1.00) 		0.896
(1.00) 		0.00339
(1.00) 		0.756
(1.00) 		0.0788
(1.00)
GBP1 8 (4%) 194 0.277
(1.00) 		0.73
(1.00) 		0.842
(1.00) 		0.369
(1.00) 		0.743
(1.00) 		0.477
(1.00) 		0.832
(1.00) 		0.61
(1.00)
OR6B3 5 (2%) 197 0.736
(1.00) 		0.859
(1.00) 		0.767
(1.00) 		0.418
(1.00) 		0.116
(1.00) 		0.205
(1.00) 		0.781
(1.00) 		0.0763
(1.00)
OR2T27 10 (5%) 192 0.773
(1.00) 		0.0109
(1.00) 		0.265
(1.00) 		0.545
(1.00) 		0.354
(1.00) 		0.162
(1.00) 		0.512
(1.00) 		0.231
(1.00)
RAET1E 5 (2%) 197 0.849
(1.00) 		0.323
(1.00) 		0.182
(1.00) 		0.0332
(1.00) 		0.743
(1.00) 		0.0187
(1.00) 		0.551
(1.00) 		0.204
(1.00)
SHROOM1 5 (2%) 197 0.629
(1.00) 		0.861
(1.00) 		1
(1.00) 		1
(1.00) 		1
(1.00) 		0.26
(1.00) 		0.899
(1.00) 		0.0773
(1.00)
OR52I2 6 (3%) 196 0.764
(1.00) 		1
(1.00) 		0.344
(1.00) 		0.164
(1.00) 		0.768
(1.00) 		0.048
(1.00) 		0.295
(1.00) 		0.339
(1.00)
OR13C2 4 (2%) 198 0.173
(1.00) 		0.203
(1.00) 		0.0849
(1.00) 		0.0706
(1.00) 		0.453
(1.00) 		0.136
(1.00) 		0.67
(1.00) 		0.138
(1.00)
LIPC 6 (3%) 196 0.879
(1.00) 		1
(1.00) 		0.119
(1.00) 		0.747
(1.00) 		0.243
(1.00) 		0.969
(1.00) 		0.33
(1.00) 		0.972
(1.00)
FAM22F 4 (2%) 198 0.173
(1.00) 		0.0114
(1.00) 		0.0342
(1.00) 		0.0413
(1.00) 		0.18
(1.00) 		0.825
(1.00) 		0.00101
(0.803) 		0.302
(1.00)
GLRX3 4 (2%) 198 0.299
(1.00) 		0.368
(1.00) 		0.114
(1.00) 		0.0213
(1.00) 		0.451
(1.00) 		0.00792
(1.00) 		0.286
(1.00) 		0.201
(1.00)
HOXA4 5 (2%) 197 0.851
(1.00) 		0.388
(1.00) 		0.931
(1.00) 		0.844
(1.00) 		0.293
(1.00) 		0.0847
(1.00) 		0.393
(1.00) 		0.206
(1.00)
DENND4B 9 (4%) 193 0.383
(1.00) 		0.198
(1.00) 		0.0519
(1.00) 		0.217
(1.00) 		0.375
(1.00) 		0.223
(1.00) 		0.476
(1.00) 		0.38
(1.00)
ESX1 6 (3%) 196 0.879
(1.00) 		0.664
(1.00) 		0.157
(1.00) 		0.196
(1.00) 		0.881
(1.00) 		0.256
(1.00) 		0.128
(1.00) 		0.135
(1.00)
SLFN12L 6 (3%) 196 1
(1.00) 		0.282
(1.00) 		0.433
(1.00) 		0.843
(1.00) 		0.883
(1.00) 		0.813
(1.00) 		0.456
(1.00) 		0.916
(1.00)
FKBP4 5 (2%) 197 0.534
(1.00) 		0.384
(1.00) 		0.345
(1.00) 		0.247
(1.00) 		0.847
(1.00) 		0.554
(1.00) 		0.279
(1.00) 		0.431
(1.00)
AQP7 9 (4%) 193 0.911
(1.00) 		0.0226
(1.00) 		0.163
(1.00) 		0.449
(1.00) 		0.169
(1.00) 		0.233
(1.00) 		0.606
(1.00) 		0.152
(1.00)
MAP4K5 10 (5%) 192 0.384
(1.00) 		0.919
(1.00) 		0.55
(1.00) 		1
(1.00) 		1
(1.00) 		0.373
(1.00) 		0.607
(1.00) 		0.634
(1.00)
BCL11A 7 (3%) 195 0.795
(1.00) 		0.483
(1.00) 		0.755
(1.00) 		0.0733
(1.00) 		0.00489
(1.00) 		0.189
(1.00) 		0.303
(1.00) 		0.134
(1.00)
'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.058 (Fisher's exact test), Q value = 1

Table S1.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TP53 MUTATED 16 19 29
TP53 WILD-TYPE 33 60 39
'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S2.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TP53 MUTATED 33 16 16
TP53 WILD-TYPE 58 45 34
'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00025 (Fisher's exact test), Q value = 0.2

Table S3.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TP53 MUTATED 7 21 16 8 11
TP53 WILD-TYPE 29 10 42 27 26

Figure S1.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.979 (Fisher's exact test), Q value = 1

Table S4.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TP53 MUTATED 23 28 12
TP53 WILD-TYPE 52 57 25
'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00898 (Fisher's exact test), Q value = 1

Table S5.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TP53 MUTATED 24 23 17
TP53 WILD-TYPE 24 53 56

Figure S2.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S6.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TP53 MUTATED 15 22 11 14 2
TP53 WILD-TYPE 9 31 62 12 19

Figure S3.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0296 (Fisher's exact test), Q value = 1

Table S7.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TP53 MUTATED 11 10 20 16 7
TP53 WILD-TYPE 15 24 20 44 30

Figure S4.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00238 (Fisher's exact test), Q value = 1

Table S8.  Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TP53 MUTATED 14 17 14 16 3
TP53 WILD-TYPE 9 29 21 55 19

Figure S5.  Get High-res Image Gene #1: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00228 (Fisher's exact test), Q value = 1

Table S9.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CTNNB1 MUTATED 24 19 14
CTNNB1 WILD-TYPE 25 60 54

Figure S6.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'CTNNB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00017 (Fisher's exact test), Q value = 0.14

Table S10.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CTNNB1 MUTATED 39 10 8
CTNNB1 WILD-TYPE 52 51 42

Figure S7.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S11.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CTNNB1 MUTATED 5 5 10 4 33
CTNNB1 WILD-TYPE 31 26 48 31 4

Figure S8.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S12.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CTNNB1 MUTATED 8 16 33
CTNNB1 WILD-TYPE 67 69 4

Figure S9.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 1

Table S13.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CTNNB1 MUTATED 12 27 17
CTNNB1 WILD-TYPE 36 49 56
'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S14.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CTNNB1 MUTATED 8 9 11 10 18
CTNNB1 WILD-TYPE 16 44 62 16 3

Figure S10.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00059 (Fisher's exact test), Q value = 0.47

Table S15.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CTNNB1 MUTATED 8 3 11 28 6
CTNNB1 WILD-TYPE 18 31 29 32 31

Figure S11.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'CTNNB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.0081

Table S16.  Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CTNNB1 MUTATED 8 7 8 16 17
CTNNB1 WILD-TYPE 15 39 27 55 5

Figure S12.  Get High-res Image Gene #2: 'CTNNB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S17.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ARID1A MUTATED 7 8 9
ARID1A WILD-TYPE 42 71 59
'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S18.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ARID1A MUTATED 12 8 5
ARID1A WILD-TYPE 79 53 45
'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 1

Table S19.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ARID1A MUTATED 1 4 6 6 7
ARID1A WILD-TYPE 35 27 52 29 30
'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S20.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ARID1A MUTATED 8 9 7
ARID1A WILD-TYPE 67 76 30
'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S21.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ARID1A MUTATED 9 9 7
ARID1A WILD-TYPE 39 67 66
'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0213 (Fisher's exact test), Q value = 1

Table S22.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ARID1A MUTATED 5 5 5 8 2
ARID1A WILD-TYPE 19 48 68 18 19

Figure S13.  Get High-res Image Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S23.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ARID1A MUTATED 6 3 6 7 3
ARID1A WILD-TYPE 20 31 34 53 34
'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S24.  Gene #3: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ARID1A MUTATED 5 5 6 7 2
ARID1A WILD-TYPE 18 41 29 64 20
'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0217 (Fisher's exact test), Q value = 1

Table S25.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
RB1 MUTATED 1 5 11
RB1 WILD-TYPE 48 74 57

Figure S14.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00224 (Fisher's exact test), Q value = 1

Table S26.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
RB1 MUTATED 5 12 1
RB1 WILD-TYPE 86 49 49

Figure S15.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0394 (Fisher's exact test), Q value = 1

Table S27.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
RB1 MUTATED 2 3 6 7 0
RB1 WILD-TYPE 34 28 52 28 37

Figure S16.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0339 (Fisher's exact test), Q value = 1

Table S28.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
RB1 MUTATED 12 5 1
RB1 WILD-TYPE 63 80 36

Figure S17.  Get High-res Image Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S29.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
RB1 MUTATED 2 9 6
RB1 WILD-TYPE 46 67 67
'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S30.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
RB1 MUTATED 1 5 9 2 0
RB1 WILD-TYPE 23 48 64 24 21
'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0865 (Fisher's exact test), Q value = 1

Table S31.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
RB1 MUTATED 2 4 1 3 7
RB1 WILD-TYPE 24 30 39 57 30
'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S32.  Gene #4: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
RB1 MUTATED 1 3 3 10 0
RB1 WILD-TYPE 22 43 32 61 22
'AXIN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.067 (Fisher's exact test), Q value = 1

Table S33.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AXIN1 MUTATED 2 2 8
AXIN1 WILD-TYPE 47 77 60
'AXIN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S34.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AXIN1 MUTATED 5 5 2
AXIN1 WILD-TYPE 86 56 48
'AXIN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S35.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AXIN1 MUTATED 2 1 4 5 0
AXIN1 WILD-TYPE 34 30 54 30 37
'AXIN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0669 (Fisher's exact test), Q value = 1

Table S36.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AXIN1 MUTATED 8 4 0
AXIN1 WILD-TYPE 67 81 37
'AXIN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 1

Table S37.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AXIN1 MUTATED 0 6 5
AXIN1 WILD-TYPE 48 70 68
'AXIN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0475 (Fisher's exact test), Q value = 1

Table S38.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AXIN1 MUTATED 1 0 7 3 0
AXIN1 WILD-TYPE 23 53 66 23 21

Figure S18.  Get High-res Image Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'AXIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0116 (Fisher's exact test), Q value = 1

Table S39.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AXIN1 MUTATED 4 0 0 6 1
AXIN1 WILD-TYPE 22 34 40 54 36

Figure S19.  Get High-res Image Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'AXIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0764 (Fisher's exact test), Q value = 1

Table S40.  Gene #5: 'AXIN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AXIN1 MUTATED 1 0 5 4 1
AXIN1 WILD-TYPE 22 46 30 67 21
'KRTAP5-11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S41.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KRTAP5-11 MUTATED 1 1 3
KRTAP5-11 WILD-TYPE 48 78 65
'KRTAP5-11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S42.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KRTAP5-11 MUTATED 3 1 1
KRTAP5-11 WILD-TYPE 88 60 49
'KRTAP5-11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S43.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KRTAP5-11 MUTATED 1 1 3 0 0
KRTAP5-11 WILD-TYPE 35 30 55 35 37
'KRTAP5-11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S44.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KRTAP5-11 MUTATED 2 3 0
KRTAP5-11 WILD-TYPE 73 82 37
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S45.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KRTAP5-11 MUTATED 0 3 2
KRTAP5-11 WILD-TYPE 48 73 71
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S46.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KRTAP5-11 MUTATED 0 2 3 0 0
KRTAP5-11 WILD-TYPE 24 51 70 26 21
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S47.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KRTAP5-11 MUTATED 0 1 0 3 1
KRTAP5-11 WILD-TYPE 26 33 40 57 36
'KRTAP5-11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S48.  Gene #6: 'KRTAP5-11 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KRTAP5-11 MUTATED 0 2 0 3 0
KRTAP5-11 WILD-TYPE 23 44 35 68 22
'AHCTF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S49.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AHCTF1 MUTATED 4 5 4
AHCTF1 WILD-TYPE 45 74 64
'AHCTF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S50.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AHCTF1 MUTATED 8 3 2
AHCTF1 WILD-TYPE 83 58 48
'AHCTF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S51.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AHCTF1 MUTATED 1 2 4 2 4
AHCTF1 WILD-TYPE 35 29 54 33 33
'AHCTF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S52.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AHCTF1 MUTATED 3 6 4
AHCTF1 WILD-TYPE 72 79 33
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S53.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AHCTF1 MUTATED 4 6 3
AHCTF1 WILD-TYPE 44 70 70
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 1

Table S54.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AHCTF1 MUTATED 2 4 2 1 4
AHCTF1 WILD-TYPE 22 49 71 25 17
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S55.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AHCTF1 MUTATED 2 1 2 6 2
AHCTF1 WILD-TYPE 24 33 38 54 35
'AHCTF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S56.  Gene #7: 'AHCTF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AHCTF1 MUTATED 2 3 1 4 3
AHCTF1 WILD-TYPE 21 43 34 67 19
'GPATCH4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0405 (Fisher's exact test), Q value = 1

Table S57.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GPATCH4 MUTATED 3 1 7
GPATCH4 WILD-TYPE 46 78 61

Figure S20.  Get High-res Image Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'GPATCH4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S58.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GPATCH4 MUTATED 6 3 2
GPATCH4 WILD-TYPE 85 58 48
'GPATCH4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S59.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GPATCH4 MUTATED 3 3 2 1 1
GPATCH4 WILD-TYPE 33 28 56 34 36
'GPATCH4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S60.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GPATCH4 MUTATED 3 6 1
GPATCH4 WILD-TYPE 72 79 36
'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S61.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GPATCH4 MUTATED 5 2 4
GPATCH4 WILD-TYPE 43 74 69
'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S62.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GPATCH4 MUTATED 4 3 4 0 0
GPATCH4 WILD-TYPE 20 50 69 26 21
'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0436 (Fisher's exact test), Q value = 1

Table S63.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GPATCH4 MUTATED 2 3 5 1 0
GPATCH4 WILD-TYPE 24 31 35 59 37

Figure S21.  Get High-res Image Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'GPATCH4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0617 (Fisher's exact test), Q value = 1

Table S64.  Gene #8: 'GPATCH4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GPATCH4 MUTATED 4 3 0 4 0
GPATCH4 WILD-TYPE 19 43 35 67 22
'CD207 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 1

Table S65.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CD207 MUTATED 4 2 2
CD207 WILD-TYPE 45 77 66
'CD207 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 1

Table S66.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CD207 MUTATED 6 2 0
CD207 WILD-TYPE 85 59 50
'CD207 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S67.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CD207 MUTATED 0 2 1 2 2
CD207 WILD-TYPE 36 29 57 33 35
'CD207 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S68.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CD207 MUTATED 3 2 2
CD207 WILD-TYPE 72 83 35
'CD207 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S69.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CD207 MUTATED 3 2 3
CD207 WILD-TYPE 45 74 70
'CD207 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S70.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CD207 MUTATED 1 1 3 1 2
CD207 WILD-TYPE 23 52 70 25 19
'CD207 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S71.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CD207 MUTATED 0 2 2 2 2
CD207 WILD-TYPE 26 32 38 58 35
'CD207 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S72.  Gene #9: 'CD207 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CD207 MUTATED 1 1 2 2 2
CD207 WILD-TYPE 22 45 33 69 20
'EEF1A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S73.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
EEF1A1 MUTATED 2 4 3
EEF1A1 WILD-TYPE 47 75 65
'EEF1A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S74.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
EEF1A1 MUTATED 6 1 2
EEF1A1 WILD-TYPE 85 60 48
'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S75.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
EEF1A1 MUTATED 1 0 5 0 3
EEF1A1 WILD-TYPE 35 31 53 35 34
'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0256 (Fisher's exact test), Q value = 1

Table S76.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
EEF1A1 MUTATED 0 6 3
EEF1A1 WILD-TYPE 75 79 34

Figure S22.  Get High-res Image Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.754 (Fisher's exact test), Q value = 1

Table S77.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
EEF1A1 MUTATED 1 4 4
EEF1A1 WILD-TYPE 47 72 69
'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S78.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
EEF1A1 MUTATED 1 3 3 0 2
EEF1A1 WILD-TYPE 23 50 70 26 19
'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S79.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
EEF1A1 MUTATED 0 2 1 5 1
EEF1A1 WILD-TYPE 26 32 39 55 36
'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S80.  Gene #10: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
EEF1A1 MUTATED 1 3 1 2 2
EEF1A1 WILD-TYPE 22 43 34 69 20
'BAP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S81.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BAP1 MUTATED 2 6 3
BAP1 WILD-TYPE 47 73 65
'BAP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00168 (Fisher's exact test), Q value = 1

Table S82.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BAP1 MUTATED 0 7 4
BAP1 WILD-TYPE 91 54 46

Figure S23.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'BAP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 5e-05 (Fisher's exact test), Q value = 0.04

Table S83.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BAP1 MUTATED 7 0 0 4 0
BAP1 WILD-TYPE 29 31 58 31 37

Figure S24.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'BAP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00095 (Fisher's exact test), Q value = 0.76

Table S84.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BAP1 MUTATED 10 1 0
BAP1 WILD-TYPE 65 84 37

Figure S25.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0212 (Fisher's exact test), Q value = 1

Table S85.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BAP1 MUTATED 0 3 8
BAP1 WILD-TYPE 48 73 65

Figure S26.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00099 (Fisher's exact test), Q value = 0.79

Table S86.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BAP1 MUTATED 0 0 11 0 0
BAP1 WILD-TYPE 24 53 62 26 21

Figure S27.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00323 (Fisher's exact test), Q value = 1

Table S87.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BAP1 MUTATED 1 2 0 1 7
BAP1 WILD-TYPE 25 32 40 59 30

Figure S28.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'BAP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0332 (Fisher's exact test), Q value = 1

Table S88.  Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BAP1 MUTATED 0 0 4 7 0
BAP1 WILD-TYPE 23 46 31 64 22

Figure S29.  Get High-res Image Gene #11: 'BAP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CHIT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 1

Table S89.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CHIT1 MUTATED 3 4 1
CHIT1 WILD-TYPE 46 75 67
'CHIT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S90.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CHIT1 MUTATED 4 2 2
CHIT1 WILD-TYPE 87 59 48
'CHIT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S91.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CHIT1 MUTATED 1 0 4 1 2
CHIT1 WILD-TYPE 35 31 54 34 35
'CHIT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S92.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CHIT1 MUTATED 2 4 2
CHIT1 WILD-TYPE 73 81 35
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S93.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CHIT1 MUTATED 1 5 2
CHIT1 WILD-TYPE 47 71 71
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S94.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CHIT1 MUTATED 0 3 3 0 2
CHIT1 WILD-TYPE 24 50 70 26 19
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S95.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CHIT1 MUTATED 1 2 0 4 1
CHIT1 WILD-TYPE 25 32 40 56 36
'CHIT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S96.  Gene #12: 'CHIT1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CHIT1 MUTATED 0 3 1 3 1
CHIT1 WILD-TYPE 23 43 34 68 21
'PPIAL4G MUTATION STATUS' versus 'CN_CNMF'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S97.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PPIAL4G MUTATED 2 2 3
PPIAL4G WILD-TYPE 47 77 65
'PPIAL4G MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S98.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PPIAL4G MUTATED 4 3 0
PPIAL4G WILD-TYPE 87 58 50
'PPIAL4G MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 1

Table S99.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PPIAL4G MUTATED 0 0 2 2 3
PPIAL4G WILD-TYPE 36 31 56 33 34
'PPIAL4G MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S100.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PPIAL4G MUTATED 2 2 3
PPIAL4G WILD-TYPE 73 83 34
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 1

Table S101.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PPIAL4G MUTATED 1 5 1
PPIAL4G WILD-TYPE 47 71 72
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 1

Table S102.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PPIAL4G MUTATED 0 2 2 0 3
PPIAL4G WILD-TYPE 24 51 71 26 18
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 1

Table S103.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PPIAL4G MUTATED 1 0 0 5 1
PPIAL4G WILD-TYPE 25 34 40 55 36
'PPIAL4G MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S104.  Gene #13: 'PPIAL4G MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PPIAL4G MUTATED 0 2 1 1 3
PPIAL4G WILD-TYPE 23 44 34 70 19
'ALB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0362 (Fisher's exact test), Q value = 1

Table S105.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ALB MUTATED 11 7 5
ALB WILD-TYPE 38 72 63

Figure S30.  Get High-res Image Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ALB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 1

Table S106.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ALB MUTATED 14 5 5
ALB WILD-TYPE 77 56 45
'ALB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S107.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ALB MUTATED 2 5 8 4 3
ALB WILD-TYPE 34 26 50 31 34
'ALB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S108.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ALB MUTATED 7 12 3
ALB WILD-TYPE 68 73 34
'ALB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S109.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ALB MUTATED 6 9 7
ALB WILD-TYPE 42 67 66
'ALB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S110.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ALB MUTATED 4 5 8 3 2
ALB WILD-TYPE 20 48 65 23 19
'ALB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S111.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ALB MUTATED 1 2 6 10 3
ALB WILD-TYPE 25 32 34 50 34
'ALB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S112.  Gene #14: 'ALB MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ALB MUTATED 4 3 5 8 2
ALB WILD-TYPE 19 43 30 63 20
'PABPC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S113.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PABPC1 MUTATED 0 4 4
PABPC1 WILD-TYPE 49 75 64
'PABPC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S114.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PABPC1 MUTATED 4 2 2
PABPC1 WILD-TYPE 87 59 48
'PABPC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S115.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PABPC1 MUTATED 1 3 2 2 0
PABPC1 WILD-TYPE 35 28 56 33 37
'PABPC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S116.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PABPC1 MUTATED 5 2 1
PABPC1 WILD-TYPE 70 83 36
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S117.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PABPC1 MUTATED 2 2 4
PABPC1 WILD-TYPE 46 74 69
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S118.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PABPC1 MUTATED 1 2 3 2 0
PABPC1 WILD-TYPE 23 51 70 24 21
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.933 (Fisher's exact test), Q value = 1

Table S119.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PABPC1 MUTATED 1 2 1 3 1
PABPC1 WILD-TYPE 25 32 39 57 36
'PABPC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.979 (Fisher's exact test), Q value = 1

Table S120.  Gene #15: 'PABPC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PABPC1 MUTATED 1 2 2 3 0
PABPC1 WILD-TYPE 22 44 33 68 22
'TREML2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S121.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TREML2 MUTATED 2 1 2
TREML2 WILD-TYPE 47 78 66
'TREML2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S122.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TREML2 MUTATED 3 2 1
TREML2 WILD-TYPE 88 59 49
'TREML2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S123.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TREML2 MUTATED 0 0 4 0 2
TREML2 WILD-TYPE 36 31 54 35 35
'TREML2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0906 (Fisher's exact test), Q value = 1

Table S124.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TREML2 MUTATED 0 4 2
TREML2 WILD-TYPE 75 81 35
'TREML2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S125.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TREML2 MUTATED 0 3 3
TREML2 WILD-TYPE 48 73 70
'TREML2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0316 (Fisher's exact test), Q value = 1

Table S126.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TREML2 MUTATED 0 0 3 0 3
TREML2 WILD-TYPE 24 53 70 26 18

Figure S31.  Get High-res Image Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 1

Table S127.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TREML2 MUTATED 0 2 0 3 1
TREML2 WILD-TYPE 26 32 40 57 36
'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0324 (Fisher's exact test), Q value = 1

Table S128.  Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TREML2 MUTATED 0 0 0 3 3
TREML2 WILD-TYPE 23 46 35 68 19

Figure S32.  Get High-res Image Gene #16: 'TREML2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PRH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S129.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PRH2 MUTATED 2 3 1
PRH2 WILD-TYPE 47 76 67
'PRH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S130.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PRH2 MUTATED 2 2 2
PRH2 WILD-TYPE 89 59 48
'PRH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S131.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PRH2 MUTATED 0 2 1 2 1
PRH2 WILD-TYPE 36 29 57 33 36
'PRH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S132.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PRH2 MUTATED 3 2 1
PRH2 WILD-TYPE 72 83 36
'PRH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S133.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PRH2 MUTATED 2 2 2
PRH2 WILD-TYPE 46 74 71
'PRH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S134.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PRH2 MUTATED 1 2 2 0 1
PRH2 WILD-TYPE 23 51 71 26 20
'PRH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S135.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PRH2 MUTATED 2 0 2 1 1
PRH2 WILD-TYPE 24 34 38 59 36
'PRH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.971 (Fisher's exact test), Q value = 1

Table S136.  Gene #17: 'PRH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PRH2 MUTATED 1 2 1 2 0
PRH2 WILD-TYPE 22 44 34 69 22
'MUC17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S137.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MUC17 MUTATED 7 12 8
MUC17 WILD-TYPE 42 67 60
'MUC17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S138.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MUC17 MUTATED 12 8 8
MUC17 WILD-TYPE 79 53 42
'MUC17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S139.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MUC17 MUTATED 6 3 6 7 5
MUC17 WILD-TYPE 30 28 52 28 32
'MUC17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S140.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MUC17 MUTATED 11 10 6
MUC17 WILD-TYPE 64 75 31
'MUC17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S141.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MUC17 MUTATED 5 13 10
MUC17 WILD-TYPE 43 63 63
'MUC17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S142.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MUC17 MUTATED 4 6 11 2 5
MUC17 WILD-TYPE 20 47 62 24 16
'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S143.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MUC17 MUTATED 4 4 4 9 7
MUC17 WILD-TYPE 22 30 36 51 30
'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S144.  Gene #18: 'MUC17 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MUC17 MUTATED 3 5 7 8 5
MUC17 WILD-TYPE 20 41 28 63 17
'AZIN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.318 (Fisher's exact test), Q value = 1

Table S145.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AZIN1 MUTATED 1 7 5
AZIN1 WILD-TYPE 48 72 63
'AZIN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S146.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AZIN1 MUTATED 8 2 3
AZIN1 WILD-TYPE 83 59 47
'AZIN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0375 (Fisher's exact test), Q value = 1

Table S147.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AZIN1 MUTATED 1 5 6 0 1
AZIN1 WILD-TYPE 35 26 52 35 36

Figure S33.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'AZIN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S148.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AZIN1 MUTATED 4 8 1
AZIN1 WILD-TYPE 71 77 36
'AZIN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0276 (Fisher's exact test), Q value = 1

Table S149.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AZIN1 MUTATED 6 6 1
AZIN1 WILD-TYPE 42 70 72

Figure S34.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'AZIN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0152 (Fisher's exact test), Q value = 1

Table S150.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AZIN1 MUTATED 5 5 1 1 1
AZIN1 WILD-TYPE 19 48 72 25 20

Figure S35.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'AZIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S151.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AZIN1 MUTATED 0 1 6 5 1
AZIN1 WILD-TYPE 26 33 34 55 36
'AZIN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00501 (Fisher's exact test), Q value = 1

Table S152.  Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AZIN1 MUTATED 4 5 3 0 1
AZIN1 WILD-TYPE 19 41 32 71 21

Figure S36.  Get High-res Image Gene #19: 'AZIN1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NBPF3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 1

Table S153.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NBPF3 MUTATED 3 1 3
NBPF3 WILD-TYPE 46 78 65
'NBPF3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S154.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NBPF3 MUTATED 5 1 1
NBPF3 WILD-TYPE 86 60 49
'NBPF3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0353 (Fisher's exact test), Q value = 1

Table S155.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NBPF3 MUTATED 2 3 0 0 1
NBPF3 WILD-TYPE 34 28 58 35 36

Figure S37.  Get High-res Image Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'NBPF3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S156.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NBPF3 MUTATED 3 2 1
NBPF3 WILD-TYPE 72 83 36
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S157.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NBPF3 MUTATED 2 2 3
NBPF3 WILD-TYPE 46 74 70
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S158.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NBPF3 MUTATED 1 1 2 2 1
NBPF3 WILD-TYPE 23 52 71 24 20
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S159.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NBPF3 MUTATED 0 3 1 2 1
NBPF3 WILD-TYPE 26 31 39 58 36
'NBPF3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S160.  Gene #20: 'NBPF3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NBPF3 MUTATED 1 1 2 2 1
NBPF3 WILD-TYPE 22 45 33 69 21
'BCLAF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S161.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BCLAF1 MUTATED 3 5 6
BCLAF1 WILD-TYPE 46 74 62
'BCLAF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S162.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BCLAF1 MUTATED 8 5 1
BCLAF1 WILD-TYPE 83 56 49
'BCLAF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S163.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BCLAF1 MUTATED 1 2 5 4 2
BCLAF1 WILD-TYPE 35 29 53 31 35
'BCLAF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S164.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BCLAF1 MUTATED 5 6 3
BCLAF1 WILD-TYPE 70 79 34
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S165.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BCLAF1 MUTATED 4 5 5
BCLAF1 WILD-TYPE 44 71 68
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S166.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BCLAF1 MUTATED 2 5 4 1 2
BCLAF1 WILD-TYPE 22 48 69 25 19
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S167.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BCLAF1 MUTATED 1 1 3 4 5
BCLAF1 WILD-TYPE 25 33 37 56 32
'BCLAF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S168.  Gene #21: 'BCLAF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BCLAF1 MUTATED 2 4 2 4 2
BCLAF1 WILD-TYPE 21 42 33 67 20
'SCRN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S169.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SCRN3 MUTATED 4 2 3
SCRN3 WILD-TYPE 45 77 65
'SCRN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S170.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SCRN3 MUTATED 7 1 1
SCRN3 WILD-TYPE 84 60 49
'SCRN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S171.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SCRN3 MUTATED 1 1 5 1 1
SCRN3 WILD-TYPE 35 30 53 34 36
'SCRN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S172.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SCRN3 MUTATED 2 6 1
SCRN3 WILD-TYPE 73 79 36
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S173.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SCRN3 MUTATED 3 4 2
SCRN3 WILD-TYPE 45 72 71
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S174.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SCRN3 MUTATED 1 3 3 0 2
SCRN3 WILD-TYPE 23 50 70 26 19
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S175.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SCRN3 MUTATED 0 2 3 4 0
SCRN3 WILD-TYPE 26 32 37 56 37
'SCRN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S176.  Gene #22: 'SCRN3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SCRN3 MUTATED 1 3 1 2 2
SCRN3 WILD-TYPE 22 43 34 69 20
'MUC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.12 (Fisher's exact test), Q value = 1

Table S177.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MUC6 MUTATED 6 6 13
MUC6 WILD-TYPE 43 73 55
'MUC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0854 (Fisher's exact test), Q value = 1

Table S178.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MUC6 MUTATED 15 8 2
MUC6 WILD-TYPE 76 53 48
'MUC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S179.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MUC6 MUTATED 2 6 7 5 5
MUC6 WILD-TYPE 34 25 51 30 32
'MUC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S180.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MUC6 MUTATED 10 10 5
MUC6 WILD-TYPE 65 75 32
'MUC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S181.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MUC6 MUTATED 7 11 7
MUC6 WILD-TYPE 41 65 66
'MUC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S182.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MUC6 MUTATED 4 8 7 1 5
MUC6 WILD-TYPE 20 45 66 25 16
'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.436 (Fisher's exact test), Q value = 1

Table S183.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MUC6 MUTATED 1 3 5 11 5
MUC6 WILD-TYPE 25 31 35 49 32
'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.307 (Fisher's exact test), Q value = 1

Table S184.  Gene #23: 'MUC6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MUC6 MUTATED 3 7 5 5 5
MUC6 WILD-TYPE 20 39 30 66 17
'UGT2B28 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S185.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
UGT2B28 MUTATED 5 3 3
UGT2B28 WILD-TYPE 44 76 65
'UGT2B28 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 1

Table S186.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
UGT2B28 MUTATED 3 6 2
UGT2B28 WILD-TYPE 88 55 48
'UGT2B28 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.14 (Fisher's exact test), Q value = 1

Table S187.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
UGT2B28 MUTATED 1 1 1 4 4
UGT2B28 WILD-TYPE 35 30 57 31 33
'UGT2B28 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.13 (Fisher's exact test), Q value = 1

Table S188.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
UGT2B28 MUTATED 5 2 4
UGT2B28 WILD-TYPE 70 83 33
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S189.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
UGT2B28 MUTATED 0 6 5
UGT2B28 WILD-TYPE 48 70 68
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S190.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
UGT2B28 MUTATED 0 2 6 0 3
UGT2B28 WILD-TYPE 24 51 67 26 18
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S191.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
UGT2B28 MUTATED 1 1 1 5 3
UGT2B28 WILD-TYPE 25 33 39 55 34
'UGT2B28 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.293 (Fisher's exact test), Q value = 1

Table S192.  Gene #24: 'UGT2B28 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
UGT2B28 MUTATED 0 2 3 3 3
UGT2B28 WILD-TYPE 23 44 32 68 19
'CDHR5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.055 (Fisher's exact test), Q value = 1

Table S193.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CDHR5 MUTATED 5 1 5
CDHR5 WILD-TYPE 44 78 63
'CDHR5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S194.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CDHR5 MUTATED 7 4 0
CDHR5 WILD-TYPE 84 57 50
'CDHR5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S195.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CDHR5 MUTATED 2 1 3 2 3
CDHR5 WILD-TYPE 34 30 55 33 34
'CDHR5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S196.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CDHR5 MUTATED 4 4 3
CDHR5 WILD-TYPE 71 81 34
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S197.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CDHR5 MUTATED 3 5 3
CDHR5 WILD-TYPE 45 71 70
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S198.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CDHR5 MUTATED 1 4 3 1 2
CDHR5 WILD-TYPE 23 49 70 25 19
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S199.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CDHR5 MUTATED 1 2 1 5 2
CDHR5 WILD-TYPE 25 32 39 55 35
'CDHR5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S200.  Gene #25: 'CDHR5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CDHR5 MUTATED 1 3 2 3 2
CDHR5 WILD-TYPE 22 43 33 68 20
'KCTD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.024 (Fisher's exact test), Q value = 1

Table S201.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KCTD3 MUTATED 1 0 5
KCTD3 WILD-TYPE 48 79 63

Figure S38.  Get High-res Image Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'KCTD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.376 (Fisher's exact test), Q value = 1

Table S202.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KCTD3 MUTATED 3 3 0
KCTD3 WILD-TYPE 88 58 50
'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S203.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KCTD3 MUTATED 0 1 2 1 2
KCTD3 WILD-TYPE 36 30 56 34 35
'KCTD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S204.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KCTD3 MUTATED 2 2 2
KCTD3 WILD-TYPE 73 83 35
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S205.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KCTD3 MUTATED 1 4 1
KCTD3 WILD-TYPE 47 72 72
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S206.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KCTD3 MUTATED 0 2 2 0 2
KCTD3 WILD-TYPE 24 51 71 26 19
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S207.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KCTD3 MUTATED 1 0 1 4 0
KCTD3 WILD-TYPE 25 34 39 56 37
'KCTD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.309 (Fisher's exact test), Q value = 1

Table S208.  Gene #26: 'KCTD3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KCTD3 MUTATED 0 2 0 2 2
KCTD3 WILD-TYPE 23 44 35 69 20
'CDC27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S209.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CDC27 MUTATED 5 4 5
CDC27 WILD-TYPE 44 75 63
'CDC27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S210.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CDC27 MUTATED 8 5 1
CDC27 WILD-TYPE 83 56 49
'CDC27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.054 (Fisher's exact test), Q value = 1

Table S211.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CDC27 MUTATED 1 2 1 5 5
CDC27 WILD-TYPE 35 29 57 30 32
'CDC27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00473 (Fisher's exact test), Q value = 1

Table S212.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CDC27 MUTATED 7 1 6
CDC27 WILD-TYPE 68 84 31

Figure S39.  Get High-res Image Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'CDC27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S213.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CDC27 MUTATED 1 9 4
CDC27 WILD-TYPE 47 67 69
'CDC27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0196 (Fisher's exact test), Q value = 1

Table S214.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CDC27 MUTATED 1 1 4 3 5
CDC27 WILD-TYPE 23 52 69 23 16

Figure S40.  Get High-res Image Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'CDC27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 1

Table S215.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CDC27 MUTATED 3 0 1 7 3
CDC27 WILD-TYPE 23 34 39 53 34
'CDC27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0577 (Fisher's exact test), Q value = 1

Table S216.  Gene #27: 'CDC27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CDC27 MUTATED 1 1 3 4 5
CDC27 WILD-TYPE 22 45 32 67 17
'CR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.954 (Fisher's exact test), Q value = 1

Table S217.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CR1 MUTATED 5 7 7
CR1 WILD-TYPE 44 72 61
'CR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S218.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CR1 MUTATED 10 5 4
CR1 WILD-TYPE 81 56 46
'CR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S219.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CR1 MUTATED 3 2 7 1 5
CR1 WILD-TYPE 33 29 51 34 32
'CR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S220.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CR1 MUTATED 5 8 5
CR1 WILD-TYPE 70 77 32
'CR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S221.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CR1 MUTATED 6 9 4
CR1 WILD-TYPE 42 67 69
'CR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S222.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CR1 MUTATED 2 7 4 2 4
CR1 WILD-TYPE 22 46 69 24 17
'CR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S223.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CR1 MUTATED 3 1 3 8 4
CR1 WILD-TYPE 23 33 37 52 33
'CR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S224.  Gene #28: 'CR1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CR1 MUTATED 2 6 3 5 3
CR1 WILD-TYPE 21 40 32 66 19
'TCEAL6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0383 (Fisher's exact test), Q value = 1

Table S225.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TCEAL6 MUTATED 3 0 1
TCEAL6 WILD-TYPE 46 79 67

Figure S41.  Get High-res Image Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'TCEAL6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.154 (Fisher's exact test), Q value = 1

Table S226.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TCEAL6 MUTATED 4 0 0
TCEAL6 WILD-TYPE 87 61 50
'TCEAL6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0622 (Fisher's exact test), Q value = 1

Table S227.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TCEAL6 MUTATED 0 2 0 0 1
TCEAL6 WILD-TYPE 36 29 58 35 36
'TCEAL6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S228.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TCEAL6 MUTATED 1 1 1
TCEAL6 WILD-TYPE 74 84 36
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S229.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TCEAL6 MUTATED 2 1 1
TCEAL6 WILD-TYPE 46 75 72
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.274 (Fisher's exact test), Q value = 1

Table S230.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TCEAL6 MUTATED 1 0 1 1 1
TCEAL6 WILD-TYPE 23 53 72 25 20
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S231.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TCEAL6 MUTATED 0 1 1 1 1
TCEAL6 WILD-TYPE 26 33 39 59 36
'TCEAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S232.  Gene #29: 'TCEAL6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TCEAL6 MUTATED 1 0 1 1 1
TCEAL6 WILD-TYPE 22 46 34 70 21
'LILRA6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 1

Table S233.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LILRA6 MUTATED 5 4 2
LILRA6 WILD-TYPE 44 75 66
'LILRA6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 1

Table S234.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LILRA6 MUTATED 8 2 1
LILRA6 WILD-TYPE 83 59 49
'LILRA6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S235.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LILRA6 MUTATED 1 1 3 1 5
LILRA6 WILD-TYPE 35 30 55 34 32
'LILRA6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0781 (Fisher's exact test), Q value = 1

Table S236.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LILRA6 MUTATED 2 4 5
LILRA6 WILD-TYPE 73 81 32
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 1

Table S237.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LILRA6 MUTATED 3 7 1
LILRA6 WILD-TYPE 45 69 72
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00605 (Fisher's exact test), Q value = 1

Table S238.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LILRA6 MUTATED 1 2 1 2 5
LILRA6 WILD-TYPE 23 51 72 24 16

Figure S42.  Get High-res Image Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LILRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S239.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LILRA6 MUTATED 1 0 1 7 2
LILRA6 WILD-TYPE 25 34 39 53 35
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0374 (Fisher's exact test), Q value = 1

Table S240.  Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LILRA6 MUTATED 1 2 3 1 4
LILRA6 WILD-TYPE 22 44 32 70 18

Figure S43.  Get High-res Image Gene #30: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'BIK MUTATION STATUS' versus 'CN_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S241.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BIK MUTATED 1 0 2
BIK WILD-TYPE 48 79 66
'BIK MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S242.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BIK MUTATED 2 1 0
BIK WILD-TYPE 89 60 50
'BIK MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.716 (Fisher's exact test), Q value = 1

Table S243.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BIK MUTATED 0 1 1 1 0
BIK WILD-TYPE 36 30 57 34 37
'BIK MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S244.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BIK MUTATED 1 2 0
BIK WILD-TYPE 74 83 37
'BIK MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 1

Table S245.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BIK MUTATED 2 1 0
BIK WILD-TYPE 46 75 73
'BIK MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 1

Table S246.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BIK MUTATED 2 0 1 0 0
BIK WILD-TYPE 22 53 72 26 21
'BIK MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 1

Table S247.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BIK MUTATED 0 0 2 0 1
BIK WILD-TYPE 26 34 38 60 36
'BIK MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.03 (Fisher's exact test), Q value = 1

Table S248.  Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BIK MUTATED 2 0 1 0 0
BIK WILD-TYPE 21 46 34 71 22

Figure S44.  Get High-res Image Gene #31: 'BIK MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SRRM3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0384 (Fisher's exact test), Q value = 1

Table S249.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SRRM3 MUTATED 3 0 1
SRRM3 WILD-TYPE 46 79 67

Figure S45.  Get High-res Image Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'SRRM3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 1

Table S250.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SRRM3 MUTATED 4 0 0
SRRM3 WILD-TYPE 87 61 50
'SRRM3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 1

Table S251.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SRRM3 MUTATED 0 2 0 1 1
SRRM3 WILD-TYPE 36 29 58 34 36
'SRRM3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S252.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SRRM3 MUTATED 1 1 2
SRRM3 WILD-TYPE 74 84 35
'SRRM3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.085 (Fisher's exact test), Q value = 1

Table S253.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SRRM3 MUTATED 3 1 0
SRRM3 WILD-TYPE 45 75 73
'SRRM3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0222 (Fisher's exact test), Q value = 1

Table S254.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SRRM3 MUTATED 2 0 0 1 1
SRRM3 WILD-TYPE 22 53 73 25 20

Figure S46.  Get High-res Image Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'SRRM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S255.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SRRM3 MUTATED 1 0 1 1 1
SRRM3 WILD-TYPE 25 34 39 59 36
'SRRM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0301 (Fisher's exact test), Q value = 1

Table S256.  Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SRRM3 MUTATED 2 0 1 0 1
SRRM3 WILD-TYPE 21 46 34 71 21

Figure S47.  Get High-res Image Gene #32: 'SRRM3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MKI67 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S257.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MKI67 MUTATED 4 6 6
MKI67 WILD-TYPE 45 73 62
'MKI67 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S258.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MKI67 MUTATED 9 6 2
MKI67 WILD-TYPE 82 55 48
'MKI67 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S259.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MKI67 MUTATED 2 1 6 2 5
MKI67 WILD-TYPE 34 30 52 33 32
'MKI67 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S260.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MKI67 MUTATED 5 6 5
MKI67 WILD-TYPE 70 79 32
'MKI67 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.948 (Fisher's exact test), Q value = 1

Table S261.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MKI67 MUTATED 4 6 7
MKI67 WILD-TYPE 44 70 66
'MKI67 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S262.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MKI67 MUTATED 2 4 4 3 4
MKI67 WILD-TYPE 22 49 69 23 17
'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 1

Table S263.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MKI67 MUTATED 5 2 2 7 1
MKI67 WILD-TYPE 21 32 38 53 36
'MKI67 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S264.  Gene #33: 'MKI67 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MKI67 MUTATED 2 4 1 7 3
MKI67 WILD-TYPE 21 42 34 64 19
'ALDH3B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0117 (Fisher's exact test), Q value = 1

Table S265.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ALDH3B1 MUTATED 4 0 1
ALDH3B1 WILD-TYPE 45 79 67

Figure S48.  Get High-res Image Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ALDH3B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.074 (Fisher's exact test), Q value = 1

Table S266.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ALDH3B1 MUTATED 5 0 0
ALDH3B1 WILD-TYPE 86 61 50
'ALDH3B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S267.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ALDH3B1 MUTATED 0 2 1 0 1
ALDH3B1 WILD-TYPE 36 29 57 35 36
'ALDH3B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S268.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ALDH3B1 MUTATED 1 2 1
ALDH3B1 WILD-TYPE 74 83 36
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S269.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ALDH3B1 MUTATED 2 2 1
ALDH3B1 WILD-TYPE 46 74 72
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S270.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ALDH3B1 MUTATED 1 0 2 1 1
ALDH3B1 WILD-TYPE 23 53 71 25 20
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S271.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ALDH3B1 MUTATED 0 1 1 2 1
ALDH3B1 WILD-TYPE 26 33 39 58 36
'ALDH3B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S272.  Gene #34: 'ALDH3B1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ALDH3B1 MUTATED 1 0 1 2 1
ALDH3B1 WILD-TYPE 22 46 34 69 21
'POTEG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0931 (Fisher's exact test), Q value = 1

Table S273.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
POTEG MUTATED 6 2 5
POTEG WILD-TYPE 43 77 63
'POTEG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S274.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
POTEG MUTATED 5 6 2
POTEG WILD-TYPE 86 55 48
'POTEG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S275.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
POTEG MUTATED 1 2 3 3 3
POTEG WILD-TYPE 35 29 55 32 34
'POTEG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.419 (Fisher's exact test), Q value = 1

Table S276.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
POTEG MUTATED 6 3 3
POTEG WILD-TYPE 69 82 34
'POTEG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S277.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
POTEG MUTATED 2 7 4
POTEG WILD-TYPE 46 69 69
'POTEG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S278.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
POTEG MUTATED 0 3 5 4 1
POTEG WILD-TYPE 24 50 68 22 20
'POTEG MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 1

Table S279.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
POTEG MUTATED 1 2 0 5 5
POTEG WILD-TYPE 25 32 40 55 32
'POTEG MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.337 (Fisher's exact test), Q value = 1

Table S280.  Gene #35: 'POTEG MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
POTEG MUTATED 0 3 5 4 1
POTEG WILD-TYPE 23 43 30 67 21
'ZNF658 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0114 (Fisher's exact test), Q value = 1

Table S281.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZNF658 MUTATED 2 0 6
ZNF658 WILD-TYPE 47 79 62

Figure S49.  Get High-res Image Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'ZNF658 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.238 (Fisher's exact test), Q value = 1

Table S282.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZNF658 MUTATED 5 3 0
ZNF658 WILD-TYPE 86 58 50
'ZNF658 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.437 (Fisher's exact test), Q value = 1

Table S283.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZNF658 MUTATED 2 2 1 0 2
ZNF658 WILD-TYPE 34 29 57 35 35
'ZNF658 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S284.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZNF658 MUTATED 4 1 2
ZNF658 WILD-TYPE 71 84 35
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S285.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZNF658 MUTATED 2 3 3
ZNF658 WILD-TYPE 46 73 70
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 1

Table S286.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZNF658 MUTATED 1 0 3 2 2
ZNF658 WILD-TYPE 23 53 70 24 19
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S287.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZNF658 MUTATED 1 1 1 2 3
ZNF658 WILD-TYPE 25 33 39 58 34
'ZNF658 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S288.  Gene #36: 'ZNF658 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZNF658 MUTATED 1 0 2 3 2
ZNF658 WILD-TYPE 22 46 33 68 20
'TCHH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S289.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TCHH MUTATED 6 6 9
TCHH WILD-TYPE 43 73 59
'TCHH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0424 (Fisher's exact test), Q value = 1

Table S290.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TCHH MUTATED 13 8 1
TCHH WILD-TYPE 78 53 49

Figure S50.  Get High-res Image Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TCHH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S291.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TCHH MUTATED 2 4 7 3 6
TCHH WILD-TYPE 34 27 51 32 31
'TCHH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S292.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TCHH MUTATED 7 9 6
TCHH WILD-TYPE 68 76 31
'TCHH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S293.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TCHH MUTATED 5 9 8
TCHH WILD-TYPE 43 67 65
'TCHH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.106 (Fisher's exact test), Q value = 1

Table S294.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TCHH MUTATED 2 7 5 2 6
TCHH WILD-TYPE 22 46 68 24 15
'TCHH MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S295.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TCHH MUTATED 3 3 3 9 4
TCHH WILD-TYPE 23 31 37 51 33
'TCHH MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.323 (Fisher's exact test), Q value = 1

Table S296.  Gene #37: 'TCHH MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TCHH MUTATED 2 5 5 5 5
TCHH WILD-TYPE 21 41 30 66 17
'TMEM176A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 1

Table S297.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TMEM176A MUTATED 2 0 2
TMEM176A WILD-TYPE 47 79 66
'TMEM176A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.154 (Fisher's exact test), Q value = 1

Table S298.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TMEM176A MUTATED 4 0 0
TMEM176A WILD-TYPE 87 61 50
'TMEM176A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S299.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TMEM176A MUTATED 0 2 1 0 0
TMEM176A WILD-TYPE 36 29 57 35 37
'TMEM176A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S300.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TMEM176A MUTATED 1 2 0
TMEM176A WILD-TYPE 74 83 37
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S301.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TMEM176A MUTATED 2 0 2
TMEM176A WILD-TYPE 46 76 71
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S302.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TMEM176A MUTATED 1 1 1 1 0
TMEM176A WILD-TYPE 23 52 72 25 21
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.257 (Fisher's exact test), Q value = 1

Table S303.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TMEM176A MUTATED 0 2 1 0 1
TMEM176A WILD-TYPE 26 32 39 60 36
'TMEM176A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S304.  Gene #38: 'TMEM176A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TMEM176A MUTATED 1 1 1 1 0
TMEM176A WILD-TYPE 22 45 34 70 22
'RP1L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S305.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
RP1L1 MUTATED 6 5 9
RP1L1 WILD-TYPE 43 74 59
'RP1L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.061 (Fisher's exact test), Q value = 1

Table S306.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
RP1L1 MUTATED 12 8 1
RP1L1 WILD-TYPE 79 53 49
'RP1L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0109 (Fisher's exact test), Q value = 1

Table S307.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
RP1L1 MUTATED 0 5 6 8 2
RP1L1 WILD-TYPE 36 26 52 27 35

Figure S51.  Get High-res Image Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'RP1L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S308.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
RP1L1 MUTATED 9 10 2
RP1L1 WILD-TYPE 66 75 35
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S309.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
RP1L1 MUTATED 5 10 6
RP1L1 WILD-TYPE 43 66 67
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S310.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
RP1L1 MUTATED 2 8 6 3 2
RP1L1 WILD-TYPE 22 45 67 23 19
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S311.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
RP1L1 MUTATED 2 1 7 6 5
RP1L1 WILD-TYPE 24 33 33 54 32
'RP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 1

Table S312.  Gene #39: 'RP1L1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
RP1L1 MUTATED 2 8 5 4 2
RP1L1 WILD-TYPE 21 38 30 67 20
'TSC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 1

Table S313.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TSC2 MUTATED 2 9 4
TSC2 WILD-TYPE 47 70 64
'TSC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0452 (Fisher's exact test), Q value = 1

Table S314.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TSC2 MUTATED 7 1 7
TSC2 WILD-TYPE 84 60 43

Figure S52.  Get High-res Image Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'TSC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S315.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TSC2 MUTATED 5 3 4 2 1
TSC2 WILD-TYPE 31 28 54 33 36
'TSC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S316.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TSC2 MUTATED 7 7 1
TSC2 WILD-TYPE 68 78 36
'TSC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S317.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TSC2 MUTATED 3 7 5
TSC2 WILD-TYPE 45 69 68
'TSC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S318.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TSC2 MUTATED 2 5 7 0 1
TSC2 WILD-TYPE 22 48 66 26 20
'TSC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S319.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TSC2 MUTATED 0 3 3 6 3
TSC2 WILD-TYPE 26 31 37 54 34
'TSC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S320.  Gene #40: 'TSC2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TSC2 MUTATED 2 4 2 4 3
TSC2 WILD-TYPE 21 42 33 67 19
'PRKDC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S321.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PRKDC MUTATED 5 9 9
PRKDC WILD-TYPE 44 70 59
'PRKDC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S322.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PRKDC MUTATED 15 6 3
PRKDC WILD-TYPE 76 55 47
'PRKDC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S323.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PRKDC MUTATED 2 5 8 3 5
PRKDC WILD-TYPE 34 26 50 32 32
'PRKDC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.918 (Fisher's exact test), Q value = 1

Table S324.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PRKDC MUTATED 8 10 5
PRKDC WILD-TYPE 67 75 32
'PRKDC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S325.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PRKDC MUTATED 6 9 9
PRKDC WILD-TYPE 42 67 64
'PRKDC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.17 (Fisher's exact test), Q value = 1

Table S326.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PRKDC MUTATED 1 7 6 6 4
PRKDC WILD-TYPE 23 46 67 20 17
'PRKDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S327.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PRKDC MUTATED 3 2 5 10 4
PRKDC WILD-TYPE 23 32 35 50 33
'PRKDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S328.  Gene #41: 'PRKDC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PRKDC MUTATED 1 7 6 6 4
PRKDC WILD-TYPE 22 39 29 65 18
'NRD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S329.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NRD1 MUTATED 4 5 2
NRD1 WILD-TYPE 45 74 66
'NRD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S330.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NRD1 MUTATED 5 4 2
NRD1 WILD-TYPE 86 57 48
'NRD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S331.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NRD1 MUTATED 2 2 2 2 3
NRD1 WILD-TYPE 34 29 56 33 34
'NRD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.177 (Fisher's exact test), Q value = 1

Table S332.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NRD1 MUTATED 6 2 3
NRD1 WILD-TYPE 69 83 34
'NRD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S333.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NRD1 MUTATED 3 5 3
NRD1 WILD-TYPE 45 71 70
'NRD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.144 (Fisher's exact test), Q value = 1

Table S334.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NRD1 MUTATED 1 2 3 1 4
NRD1 WILD-TYPE 23 51 70 25 17
'NRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S335.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NRD1 MUTATED 0 3 3 4 1
NRD1 WILD-TYPE 26 31 37 56 36
'NRD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0804 (Fisher's exact test), Q value = 1

Table S336.  Gene #42: 'NRD1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NRD1 MUTATED 1 2 0 4 4
NRD1 WILD-TYPE 22 44 35 67 18
'TAS2R20 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.301 (Fisher's exact test), Q value = 1

Table S337.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TAS2R20 MUTATED 1 3 0
TAS2R20 WILD-TYPE 48 76 68
'TAS2R20 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 1

Table S338.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TAS2R20 MUTATED 2 0 2
TAS2R20 WILD-TYPE 89 61 48
'TAS2R20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.487 (Fisher's exact test), Q value = 1

Table S339.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TAS2R20 MUTATED 0 1 1 0 2
TAS2R20 WILD-TYPE 36 30 57 35 35
'TAS2R20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0106 (Fisher's exact test), Q value = 1

Table S340.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TAS2R20 MUTATED 1 0 3
TAS2R20 WILD-TYPE 74 85 34

Figure S53.  Get High-res Image Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S341.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TAS2R20 MUTATED 1 1 2
TAS2R20 WILD-TYPE 47 75 71
'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0829 (Fisher's exact test), Q value = 1

Table S342.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TAS2R20 MUTATED 0 0 1 1 2
TAS2R20 WILD-TYPE 24 53 72 25 19
'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S343.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TAS2R20 MUTATED 1 0 0 2 1
TAS2R20 WILD-TYPE 25 34 40 58 36
'TAS2R20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S344.  Gene #43: 'TAS2R20 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TAS2R20 MUTATED 0 0 1 2 1
TAS2R20 WILD-TYPE 23 46 34 69 21
'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 1

Table S345.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PTEN MUTATED 1 2 6
PTEN WILD-TYPE 48 77 62
'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0982 (Fisher's exact test), Q value = 1

Table S346.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PTEN MUTATED 5 5 0
PTEN WILD-TYPE 86 56 50
'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S347.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PTEN MUTATED 1 1 4 2 1
PTEN WILD-TYPE 35 30 54 33 36
'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S348.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PTEN MUTATED 3 5 1
PTEN WILD-TYPE 72 80 36
'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S349.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PTEN MUTATED 3 2 5
PTEN WILD-TYPE 45 74 68
'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.829 (Fisher's exact test), Q value = 1

Table S350.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PTEN MUTATED 0 3 4 2 1
PTEN WILD-TYPE 24 50 69 24 20
'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S351.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PTEN MUTATED 1 1 2 3 3
PTEN WILD-TYPE 25 33 38 57 34
'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S352.  Gene #44: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PTEN MUTATED 0 3 1 5 1
PTEN WILD-TYPE 23 43 34 66 21
'CYFIP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S353.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CYFIP2 MUTATED 4 4 5
CYFIP2 WILD-TYPE 45 75 63
'CYFIP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S354.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CYFIP2 MUTATED 7 4 2
CYFIP2 WILD-TYPE 84 57 48
'CYFIP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S355.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CYFIP2 MUTATED 4 2 2 2 2
CYFIP2 WILD-TYPE 32 29 56 33 35
'CYFIP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S356.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CYFIP2 MUTATED 7 3 2
CYFIP2 WILD-TYPE 68 82 35
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S357.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CYFIP2 MUTATED 3 2 7
CYFIP2 WILD-TYPE 45 74 66
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S358.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CYFIP2 MUTATED 1 2 6 2 1
CYFIP2 WILD-TYPE 23 51 67 24 20
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 1

Table S359.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CYFIP2 MUTATED 2 1 1 3 5
CYFIP2 WILD-TYPE 24 33 39 57 32
'CYFIP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S360.  Gene #45: 'CYFIP2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CYFIP2 MUTATED 1 1 2 7 1
CYFIP2 WILD-TYPE 22 45 33 64 21
'PRAMEF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S361.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PRAMEF1 MUTATED 2 4 3
PRAMEF1 WILD-TYPE 47 75 65
'PRAMEF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S362.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PRAMEF1 MUTATED 6 2 1
PRAMEF1 WILD-TYPE 85 59 49
'PRAMEF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S363.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PRAMEF1 MUTATED 0 1 3 1 4
PRAMEF1 WILD-TYPE 36 30 55 34 33
'PRAMEF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 1

Table S364.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PRAMEF1 MUTATED 2 3 4
PRAMEF1 WILD-TYPE 73 82 33
'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S365.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PRAMEF1 MUTATED 2 5 2
PRAMEF1 WILD-TYPE 46 71 71
'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0206 (Fisher's exact test), Q value = 1

Table S366.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PRAMEF1 MUTATED 0 3 1 1 4
PRAMEF1 WILD-TYPE 24 50 72 25 17

Figure S54.  Get High-res Image Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0642 (Fisher's exact test), Q value = 1

Table S367.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PRAMEF1 MUTATED 2 0 0 6 1
PRAMEF1 WILD-TYPE 24 34 40 54 36
'PRAMEF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S368.  Gene #46: 'PRAMEF1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PRAMEF1 MUTATED 0 3 1 2 3
PRAMEF1 WILD-TYPE 23 43 34 69 19
'MST1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 1

Table S369.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MST1 MUTATED 3 4 1
MST1 WILD-TYPE 46 75 67
'MST1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S370.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MST1 MUTATED 5 1 2
MST1 WILD-TYPE 86 60 48
'MST1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.636 (Fisher's exact test), Q value = 1

Table S371.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MST1 MUTATED 1 2 2 0 2
MST1 WILD-TYPE 35 29 56 35 35
'MST1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S372.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MST1 MUTATED 2 3 2
MST1 WILD-TYPE 73 82 35
'MST1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S373.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MST1 MUTATED 2 4 2
MST1 WILD-TYPE 46 72 71
'MST1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S374.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MST1 MUTATED 1 2 2 1 2
MST1 WILD-TYPE 23 51 71 25 19
'MST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.965 (Fisher's exact test), Q value = 1

Table S375.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MST1 MUTATED 1 1 1 3 2
MST1 WILD-TYPE 25 33 39 57 35
'MST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S376.  Gene #47: 'MST1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MST1 MUTATED 1 1 2 3 1
MST1 WILD-TYPE 22 45 33 68 21
'ZC3H7A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.258 (Fisher's exact test), Q value = 1

Table S377.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZC3H7A MUTATED 5 5 2
ZC3H7A WILD-TYPE 44 74 66
'ZC3H7A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S378.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZC3H7A MUTATED 7 3 2
ZC3H7A WILD-TYPE 84 58 48
'ZC3H7A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S379.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZC3H7A MUTATED 1 2 3 2 4
ZC3H7A WILD-TYPE 35 29 55 33 33
'ZC3H7A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S380.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZC3H7A MUTATED 4 5 3
ZC3H7A WILD-TYPE 71 80 34
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 1

Table S381.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZC3H7A MUTATED 3 7 2
ZC3H7A WILD-TYPE 45 69 71
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S382.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZC3H7A MUTATED 1 4 3 2 2
ZC3H7A WILD-TYPE 23 49 70 24 19
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 1

Table S383.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZC3H7A MUTATED 1 0 2 7 2
ZC3H7A WILD-TYPE 25 34 38 53 35
'ZC3H7A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S384.  Gene #48: 'ZC3H7A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZC3H7A MUTATED 1 4 4 1 2
ZC3H7A WILD-TYPE 22 42 31 70 20
'MLL3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S385.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MLL3 MUTATED 9 9 12
MLL3 WILD-TYPE 40 70 56
'MLL3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S386.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MLL3 MUTATED 14 11 5
MLL3 WILD-TYPE 77 50 45
'MLL3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0177 (Fisher's exact test), Q value = 1

Table S387.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MLL3 MUTATED 1 10 7 6 6
MLL3 WILD-TYPE 35 21 51 29 31

Figure S55.  Get High-res Image Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'MLL3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S388.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MLL3 MUTATED 13 10 7
MLL3 WILD-TYPE 62 75 30
'MLL3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.907 (Fisher's exact test), Q value = 1

Table S389.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MLL3 MUTATED 8 12 10
MLL3 WILD-TYPE 40 64 63
'MLL3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S390.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MLL3 MUTATED 4 8 8 5 5
MLL3 WILD-TYPE 20 45 65 21 16
'MLL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.149 (Fisher's exact test), Q value = 1

Table S391.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MLL3 MUTATED 4 1 8 9 8
MLL3 WILD-TYPE 22 33 32 51 29
'MLL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S392.  Gene #49: 'MLL3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MLL3 MUTATED 4 7 6 9 4
MLL3 WILD-TYPE 19 39 29 62 18
'HNRNPCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S393.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
HNRNPCL1 MUTATED 1 3 7
HNRNPCL1 WILD-TYPE 48 76 61
'HNRNPCL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S394.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
HNRNPCL1 MUTATED 5 4 2
HNRNPCL1 WILD-TYPE 86 57 48
'HNRNPCL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S395.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
HNRNPCL1 MUTATED 2 0 4 3 1
HNRNPCL1 WILD-TYPE 34 31 54 32 36
'HNRNPCL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S396.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
HNRNPCL1 MUTATED 5 4 1
HNRNPCL1 WILD-TYPE 70 81 36
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.193 (Fisher's exact test), Q value = 1

Table S397.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
HNRNPCL1 MUTATED 1 3 7
HNRNPCL1 WILD-TYPE 47 73 66
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 1

Table S398.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
HNRNPCL1 MUTATED 0 3 7 0 1
HNRNPCL1 WILD-TYPE 24 50 66 26 20
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S399.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
HNRNPCL1 MUTATED 1 3 1 3 3
HNRNPCL1 WILD-TYPE 25 31 39 57 34
'HNRNPCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S400.  Gene #50: 'HNRNPCL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
HNRNPCL1 MUTATED 0 3 2 5 1
HNRNPCL1 WILD-TYPE 23 43 33 66 21
'TUBA3E MUTATION STATUS' versus 'CN_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S401.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TUBA3E MUTATED 2 2 3
TUBA3E WILD-TYPE 47 77 65
'TUBA3E MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S402.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TUBA3E MUTATED 4 2 1
TUBA3E WILD-TYPE 87 59 49
'TUBA3E MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 1

Table S403.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TUBA3E MUTATED 0 1 1 1 4
TUBA3E WILD-TYPE 36 30 57 34 33
'TUBA3E MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0658 (Fisher's exact test), Q value = 1

Table S404.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TUBA3E MUTATED 1 2 4
TUBA3E WILD-TYPE 74 83 33
'TUBA3E MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S405.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TUBA3E MUTATED 1 4 2
TUBA3E WILD-TYPE 47 72 71
'TUBA3E MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00747 (Fisher's exact test), Q value = 1

Table S406.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TUBA3E MUTATED 1 1 1 0 4
TUBA3E WILD-TYPE 23 52 72 26 17

Figure S56.  Get High-res Image Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'TUBA3E MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S407.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TUBA3E MUTATED 2 0 1 4 0
TUBA3E WILD-TYPE 24 34 39 56 37
'TUBA3E MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 1

Table S408.  Gene #51: 'TUBA3E MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TUBA3E MUTATED 1 1 0 2 3
TUBA3E WILD-TYPE 22 45 35 69 19
'MUC21 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S409.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MUC21 MUTATED 3 5 7
MUC21 WILD-TYPE 46 74 61
'MUC21 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S410.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MUC21 MUTATED 7 5 4
MUC21 WILD-TYPE 84 56 46
'MUC21 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S411.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MUC21 MUTATED 4 3 4 2 2
MUC21 WILD-TYPE 32 28 54 33 35
'MUC21 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S412.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MUC21 MUTATED 4 9 2
MUC21 WILD-TYPE 71 76 35
'MUC21 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S413.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MUC21 MUTATED 3 7 6
MUC21 WILD-TYPE 45 69 67
'MUC21 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S414.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MUC21 MUTATED 2 5 5 1 3
MUC21 WILD-TYPE 22 48 68 25 18
'MUC21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S415.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MUC21 MUTATED 3 4 3 5 1
MUC21 WILD-TYPE 23 30 37 55 36
'MUC21 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S416.  Gene #52: 'MUC21 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MUC21 MUTATED 2 4 1 6 3
MUC21 WILD-TYPE 21 42 34 65 19
'HPS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.175 (Fisher's exact test), Q value = 1

Table S417.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
HPS4 MUTATED 1 4 0
HPS4 WILD-TYPE 48 75 68
'HPS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0566 (Fisher's exact test), Q value = 1

Table S418.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
HPS4 MUTATED 0 3 2
HPS4 WILD-TYPE 91 58 48
'HPS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 1

Table S419.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
HPS4 MUTATED 1 0 1 0 3
HPS4 WILD-TYPE 35 31 57 35 34
'HPS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.105 (Fisher's exact test), Q value = 1

Table S420.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
HPS4 MUTATED 1 1 3
HPS4 WILD-TYPE 74 84 34
'HPS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S421.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
HPS4 MUTATED 0 3 2
HPS4 WILD-TYPE 48 73 71
'HPS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S422.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
HPS4 MUTATED 0 1 1 1 2
HPS4 WILD-TYPE 24 52 72 25 19
'HPS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S423.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
HPS4 MUTATED 1 0 1 2 1
HPS4 WILD-TYPE 25 34 39 58 36
'HPS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S424.  Gene #53: 'HPS4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
HPS4 MUTATED 0 1 1 2 1
HPS4 WILD-TYPE 23 45 34 69 21
'OR2T4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0162 (Fisher's exact test), Q value = 1

Table S425.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR2T4 MUTATED 5 1 8
OR2T4 WILD-TYPE 44 78 60

Figure S57.  Get High-res Image Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

'OR2T4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0546 (Fisher's exact test), Q value = 1

Table S426.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR2T4 MUTATED 8 6 0
OR2T4 WILD-TYPE 83 55 50
'OR2T4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0532 (Fisher's exact test), Q value = 1

Table S427.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR2T4 MUTATED 2 1 1 4 6
OR2T4 WILD-TYPE 34 30 57 31 31
'OR2T4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0128 (Fisher's exact test), Q value = 1

Table S428.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR2T4 MUTATED 4 3 7
OR2T4 WILD-TYPE 71 82 30

Figure S58.  Get High-res Image Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'OR2T4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S429.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR2T4 MUTATED 3 4 7
OR2T4 WILD-TYPE 45 72 66
'OR2T4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S430.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR2T4 MUTATED 2 2 4 2 4
OR2T4 WILD-TYPE 22 51 69 24 17
'OR2T4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S431.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR2T4 MUTATED 3 3 1 5 2
OR2T4 WILD-TYPE 23 31 39 55 35
'OR2T4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.167 (Fisher's exact test), Q value = 1

Table S432.  Gene #54: 'OR2T4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR2T4 MUTATED 2 1 3 4 4
OR2T4 WILD-TYPE 21 45 32 67 18
'SPDYE1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.235 (Fisher's exact test), Q value = 1

Table S433.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SPDYE1 MUTATED 2 2 0
SPDYE1 WILD-TYPE 47 77 68
'SPDYE1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S434.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SPDYE1 MUTATED 3 0 1
SPDYE1 WILD-TYPE 88 61 49
'SPDYE1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S435.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SPDYE1 MUTATED 0 1 1 0 2
SPDYE1 WILD-TYPE 36 30 57 35 35
'SPDYE1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.144 (Fisher's exact test), Q value = 1

Table S436.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SPDYE1 MUTATED 0 2 2
SPDYE1 WILD-TYPE 75 83 35
'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S437.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SPDYE1 MUTATED 0 3 1
SPDYE1 WILD-TYPE 48 73 72
'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0425 (Fisher's exact test), Q value = 1

Table S438.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SPDYE1 MUTATED 0 2 0 0 2
SPDYE1 WILD-TYPE 24 51 73 26 19

Figure S59.  Get High-res Image Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S439.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SPDYE1 MUTATED 1 0 1 2 0
SPDYE1 WILD-TYPE 25 34 39 58 37
'SPDYE1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S440.  Gene #55: 'SPDYE1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SPDYE1 MUTATED 0 2 0 1 1
SPDYE1 WILD-TYPE 23 44 35 70 21
'COG2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 1

Table S441.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
COG2 MUTATED 3 1 2
COG2 WILD-TYPE 46 78 66
'COG2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 1

Table S442.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
COG2 MUTATED 5 0 1
COG2 WILD-TYPE 86 61 49
'COG2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S443.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
COG2 MUTATED 1 2 1 0 1
COG2 WILD-TYPE 35 29 57 35 36
'COG2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S444.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
COG2 MUTATED 1 3 1
COG2 WILD-TYPE 74 82 36
'COG2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0742 (Fisher's exact test), Q value = 1

Table S445.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
COG2 MUTATED 4 1 1
COG2 WILD-TYPE 44 75 72
'COG2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S446.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
COG2 MUTATED 2 1 1 1 1
COG2 WILD-TYPE 22 52 72 25 20
'COG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S447.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
COG2 MUTATED 0 1 3 1 1
COG2 WILD-TYPE 26 33 37 59 36
'COG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 1

Table S448.  Gene #56: 'COG2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
COG2 MUTATED 2 1 1 1 1
COG2 WILD-TYPE 21 45 34 70 21
'SEC63 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0535 (Fisher's exact test), Q value = 1

Table S449.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SEC63 MUTATED 6 2 2
SEC63 WILD-TYPE 43 77 66
'SEC63 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0886 (Fisher's exact test), Q value = 1

Table S450.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SEC63 MUTATED 8 1 1
SEC63 WILD-TYPE 83 60 49
'SEC63 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.219 (Fisher's exact test), Q value = 1

Table S451.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SEC63 MUTATED 0 3 1 2 2
SEC63 WILD-TYPE 36 28 57 33 35
'SEC63 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S452.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SEC63 MUTATED 2 4 2
SEC63 WILD-TYPE 73 81 35
'SEC63 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S453.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SEC63 MUTATED 4 3 3
SEC63 WILD-TYPE 44 73 70
'SEC63 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.16 (Fisher's exact test), Q value = 1

Table S454.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SEC63 MUTATED 2 3 1 3 1
SEC63 WILD-TYPE 22 50 72 23 20
'SEC63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S455.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SEC63 MUTATED 1 2 3 2 2
SEC63 WILD-TYPE 25 32 37 58 35
'SEC63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S456.  Gene #57: 'SEC63 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SEC63 MUTATED 2 2 2 3 1
SEC63 WILD-TYPE 21 44 33 68 21
'LILRA3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 1

Table S457.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LILRA3 MUTATED 2 2 0
LILRA3 WILD-TYPE 47 77 68
'LILRA3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.213 (Fisher's exact test), Q value = 1

Table S458.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LILRA3 MUTATED 4 0 1
LILRA3 WILD-TYPE 87 61 49
'LILRA3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0226 (Fisher's exact test), Q value = 1

Table S459.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LILRA3 MUTATED 0 0 1 0 4
LILRA3 WILD-TYPE 36 31 57 35 33

Figure S60.  Get High-res Image Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'LILRA3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00464 (Fisher's exact test), Q value = 1

Table S460.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LILRA3 MUTATED 0 1 4
LILRA3 WILD-TYPE 75 84 33

Figure S61.  Get High-res Image Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'LILRA3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S461.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LILRA3 MUTATED 0 3 2
LILRA3 WILD-TYPE 48 73 71
'LILRA3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00899 (Fisher's exact test), Q value = 1

Table S462.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LILRA3 MUTATED 0 2 0 0 3
LILRA3 WILD-TYPE 24 51 73 26 18

Figure S62.  Get High-res Image Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'LILRA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S463.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LILRA3 MUTATED 1 0 0 4 0
LILRA3 WILD-TYPE 25 34 40 56 37
'LILRA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S464.  Gene #58: 'LILRA3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LILRA3 MUTATED 0 2 0 1 2
LILRA3 WILD-TYPE 23 44 35 70 20
'CYP2A6 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S465.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CYP2A6 MUTATED 1 3 2
CYP2A6 WILD-TYPE 48 76 66
'CYP2A6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.172 (Fisher's exact test), Q value = 1

Table S466.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CYP2A6 MUTATED 3 0 3
CYP2A6 WILD-TYPE 88 61 47
'CYP2A6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S467.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CYP2A6 MUTATED 1 1 3 0 1
CYP2A6 WILD-TYPE 35 30 55 35 36
'CYP2A6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0741 (Fisher's exact test), Q value = 1

Table S468.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CYP2A6 MUTATED 0 5 1
CYP2A6 WILD-TYPE 75 80 36
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S469.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CYP2A6 MUTATED 1 3 2
CYP2A6 WILD-TYPE 47 73 71
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S470.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CYP2A6 MUTATED 1 3 2 0 0
CYP2A6 WILD-TYPE 23 50 71 26 21
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.562 (Fisher's exact test), Q value = 1

Table S471.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CYP2A6 MUTATED 2 1 1 2 0
CYP2A6 WILD-TYPE 24 33 39 58 37
'CYP2A6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S472.  Gene #59: 'CYP2A6 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CYP2A6 MUTATED 1 3 0 2 0
CYP2A6 WILD-TYPE 22 43 35 69 22
'ZC3H11A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.373 (Fisher's exact test), Q value = 1

Table S473.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZC3H11A MUTATED 0 2 3
ZC3H11A WILD-TYPE 49 77 65
'ZC3H11A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S474.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZC3H11A MUTATED 1 3 2
ZC3H11A WILD-TYPE 90 58 48
'ZC3H11A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 1

Table S475.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZC3H11A MUTATED 1 2 0 2 1
ZC3H11A WILD-TYPE 35 29 58 33 36
'ZC3H11A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S476.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZC3H11A MUTATED 4 1 1
ZC3H11A WILD-TYPE 71 84 36
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S477.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZC3H11A MUTATED 1 2 3
ZC3H11A WILD-TYPE 47 74 70
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.239 (Fisher's exact test), Q value = 1

Table S478.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZC3H11A MUTATED 1 0 3 2 0
ZC3H11A WILD-TYPE 23 53 70 24 21
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S479.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZC3H11A MUTATED 1 1 1 1 2
ZC3H11A WILD-TYPE 25 33 39 59 35
'ZC3H11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.186 (Fisher's exact test), Q value = 1

Table S480.  Gene #60: 'ZC3H11A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZC3H11A MUTATED 1 0 3 2 0
ZC3H11A WILD-TYPE 22 46 32 69 22
'LCE4A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 1

Table S481.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LCE4A MUTATED 5 3 2
LCE4A WILD-TYPE 44 76 66
'LCE4A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S482.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LCE4A MUTATED 6 3 1
LCE4A WILD-TYPE 85 58 49
'LCE4A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S483.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LCE4A MUTATED 2 3 1 2 1
LCE4A WILD-TYPE 34 28 57 33 36
'LCE4A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S484.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LCE4A MUTATED 4 4 1
LCE4A WILD-TYPE 71 81 36
'LCE4A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S485.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LCE4A MUTATED 3 3 4
LCE4A WILD-TYPE 45 73 69
'LCE4A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S486.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LCE4A MUTATED 2 2 5 0 1
LCE4A WILD-TYPE 22 51 68 26 20
'LCE4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0521 (Fisher's exact test), Q value = 1

Table S487.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LCE4A MUTATED 0 4 4 2 0
LCE4A WILD-TYPE 26 30 36 58 37
'LCE4A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S488.  Gene #61: 'LCE4A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LCE4A MUTATED 2 2 1 4 1
LCE4A WILD-TYPE 21 44 34 67 21
'ATXN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 1

Table S489.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ATXN3 MUTATED 0 5 1
ATXN3 WILD-TYPE 49 74 67
'ATXN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S490.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ATXN3 MUTATED 1 3 2
ATXN3 WILD-TYPE 90 58 48
'ATXN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S491.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ATXN3 MUTATED 2 0 2 1 1
ATXN3 WILD-TYPE 34 31 56 34 36
'ATXN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S492.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ATXN3 MUTATED 3 2 1
ATXN3 WILD-TYPE 72 83 36
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S493.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ATXN3 MUTATED 0 3 3
ATXN3 WILD-TYPE 48 73 70
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S494.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ATXN3 MUTATED 0 2 2 1 1
ATXN3 WILD-TYPE 24 51 71 25 20
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 1

Table S495.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ATXN3 MUTATED 1 0 0 2 3
ATXN3 WILD-TYPE 25 34 40 58 34
'ATXN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S496.  Gene #62: 'ATXN3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ATXN3 MUTATED 0 1 1 4 0
ATXN3 WILD-TYPE 23 45 34 67 22
'GTF2IRD2B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0648 (Fisher's exact test), Q value = 1

Table S497.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GTF2IRD2B MUTATED 3 0 2
GTF2IRD2B WILD-TYPE 46 79 66
'GTF2IRD2B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0728 (Fisher's exact test), Q value = 1

Table S498.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GTF2IRD2B MUTATED 5 0 0
GTF2IRD2B WILD-TYPE 86 61 50
'GTF2IRD2B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.133 (Fisher's exact test), Q value = 1

Table S499.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GTF2IRD2B MUTATED 0 2 0 1 1
GTF2IRD2B WILD-TYPE 36 29 58 34 36
'GTF2IRD2B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.315 (Fisher's exact test), Q value = 1

Table S500.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GTF2IRD2B MUTATED 1 1 2
GTF2IRD2B WILD-TYPE 74 84 35
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 1

Table S501.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GTF2IRD2B MUTATED 3 1 1
GTF2IRD2B WILD-TYPE 45 75 72
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 1

Table S502.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GTF2IRD2B MUTATED 2 0 1 1 1
GTF2IRD2B WILD-TYPE 22 53 72 25 20
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S503.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GTF2IRD2B MUTATED 1 1 1 1 1
GTF2IRD2B WILD-TYPE 25 33 39 59 36
'GTF2IRD2B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 1

Table S504.  Gene #63: 'GTF2IRD2B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GTF2IRD2B MUTATED 2 0 1 1 1
GTF2IRD2B WILD-TYPE 21 46 34 70 21
'QRICH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S505.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
QRICH2 MUTATED 3 11 5
QRICH2 WILD-TYPE 46 68 63
'QRICH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S506.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
QRICH2 MUTATED 10 3 6
QRICH2 WILD-TYPE 81 58 44
'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 1

Table S507.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
QRICH2 MUTATED 2 2 6 1 7
QRICH2 WILD-TYPE 34 29 52 34 30
'QRICH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.214 (Fisher's exact test), Q value = 1

Table S508.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
QRICH2 MUTATED 5 7 6
QRICH2 WILD-TYPE 70 78 31
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S509.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
QRICH2 MUTATED 6 8 5
QRICH2 WILD-TYPE 42 68 68
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S510.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
QRICH2 MUTATED 2 6 4 2 5
QRICH2 WILD-TYPE 22 47 69 24 16
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 1

Table S511.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
QRICH2 MUTATED 2 3 2 11 1
QRICH2 WILD-TYPE 24 31 38 49 36
'QRICH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S512.  Gene #64: 'QRICH2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
QRICH2 MUTATED 2 6 2 5 4
QRICH2 WILD-TYPE 21 40 33 66 18
'PLAU MUTATION STATUS' versus 'CN_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S513.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PLAU MUTATED 2 1 3
PLAU WILD-TYPE 47 78 65
'PLAU MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S514.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PLAU MUTATED 4 1 1
PLAU WILD-TYPE 87 60 49
'PLAU MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 1

Table S515.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PLAU MUTATED 1 2 0 1 1
PLAU WILD-TYPE 35 29 58 34 36
'PLAU MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S516.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PLAU MUTATED 2 2 1
PLAU WILD-TYPE 73 83 36
'PLAU MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S517.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PLAU MUTATED 1 2 3
PLAU WILD-TYPE 47 74 70
'PLAU MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S518.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PLAU MUTATED 1 1 3 0 1
PLAU WILD-TYPE 23 52 70 26 20
'PLAU MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S519.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PLAU MUTATED 0 2 1 2 1
PLAU WILD-TYPE 26 32 39 58 36
'PLAU MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S520.  Gene #65: 'PLAU MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PLAU MUTATED 1 1 1 2 1
PLAU WILD-TYPE 22 45 34 69 21
'MAPKAPK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S521.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MAPKAPK2 MUTATED 0 3 1
MAPKAPK2 WILD-TYPE 49 76 67
'MAPKAPK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S522.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MAPKAPK2 MUTATED 2 2 0
MAPKAPK2 WILD-TYPE 89 59 50
'MAPKAPK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S523.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MAPKAPK2 MUTATED 0 0 2 1 1
MAPKAPK2 WILD-TYPE 36 31 56 34 36
'MAPKAPK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S524.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MAPKAPK2 MUTATED 1 2 1
MAPKAPK2 WILD-TYPE 74 83 36
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S525.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MAPKAPK2 MUTATED 0 3 1
MAPKAPK2 WILD-TYPE 48 73 72
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S526.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MAPKAPK2 MUTATED 0 1 2 0 1
MAPKAPK2 WILD-TYPE 24 52 71 26 20
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S527.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MAPKAPK2 MUTATED 0 1 0 2 1
MAPKAPK2 WILD-TYPE 26 33 40 58 36
'MAPKAPK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.146 (Fisher's exact test), Q value = 1

Table S528.  Gene #66: 'MAPKAPK2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MAPKAPK2 MUTATED 0 1 2 0 1
MAPKAPK2 WILD-TYPE 23 45 33 71 21
'NAP1L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S529.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NAP1L1 MUTATED 2 1 3
NAP1L1 WILD-TYPE 47 78 65
'NAP1L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S530.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NAP1L1 MUTATED 3 2 1
NAP1L1 WILD-TYPE 88 59 49
'NAP1L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S531.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NAP1L1 MUTATED 0 2 0 1 1
NAP1L1 WILD-TYPE 36 29 58 34 36
'NAP1L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S532.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NAP1L1 MUTATED 2 1 1
NAP1L1 WILD-TYPE 73 84 36
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S533.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NAP1L1 MUTATED 3 2 1
NAP1L1 WILD-TYPE 45 74 72
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S534.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NAP1L1 MUTATED 1 1 2 1 1
NAP1L1 WILD-TYPE 23 52 71 25 20
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S535.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NAP1L1 MUTATED 0 1 2 1 2
NAP1L1 WILD-TYPE 26 33 38 59 35
'NAP1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S536.  Gene #67: 'NAP1L1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NAP1L1 MUTATED 1 1 2 1 1
NAP1L1 WILD-TYPE 22 45 33 70 21
'FAM118A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S537.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
FAM118A MUTATED 0 2 2
FAM118A WILD-TYPE 49 77 66
'FAM118A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S538.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
FAM118A MUTATED 1 2 1
FAM118A WILD-TYPE 90 59 49
'FAM118A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S539.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
FAM118A MUTATED 0 0 1 2 1
FAM118A WILD-TYPE 36 31 57 33 36
'FAM118A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S540.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
FAM118A MUTATED 2 1 1
FAM118A WILD-TYPE 73 84 36
'FAM118A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S541.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
FAM118A MUTATED 0 1 3
FAM118A WILD-TYPE 48 75 70
'FAM118A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S542.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
FAM118A MUTATED 0 1 1 1 1
FAM118A WILD-TYPE 24 52 72 25 20
'FAM118A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S543.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
FAM118A MUTATED 2 0 0 1 1
FAM118A WILD-TYPE 24 34 40 59 36
'FAM118A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S544.  Gene #68: 'FAM118A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
FAM118A MUTATED 0 1 1 2 0
FAM118A WILD-TYPE 23 45 34 69 22
'SLC7A6OS MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S545.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SLC7A6OS MUTATED 1 2 1
SLC7A6OS WILD-TYPE 48 77 67
'SLC7A6OS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S546.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SLC7A6OS MUTATED 2 1 1
SLC7A6OS WILD-TYPE 89 60 49
'SLC7A6OS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0375 (Fisher's exact test), Q value = 1

Table S547.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SLC7A6OS MUTATED 0 3 1 0 0
SLC7A6OS WILD-TYPE 36 28 57 35 37

Figure S63.  Get High-res Image Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'SLC7A6OS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S548.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SLC7A6OS MUTATED 3 1 0
SLC7A6OS WILD-TYPE 72 84 37
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S549.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SLC7A6OS MUTATED 1 3 0
SLC7A6OS WILD-TYPE 47 73 73
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S550.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SLC7A6OS MUTATED 0 2 1 1 0
SLC7A6OS WILD-TYPE 24 51 72 25 21
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S551.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SLC7A6OS MUTATED 0 0 0 2 2
SLC7A6OS WILD-TYPE 26 34 40 58 35
'SLC7A6OS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S552.  Gene #69: 'SLC7A6OS MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SLC7A6OS MUTATED 0 1 2 1 0
SLC7A6OS WILD-TYPE 23 45 33 70 22
'NBPF10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S553.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
NBPF10 MUTATED 1 4 7
NBPF10 WILD-TYPE 48 75 61
'NBPF10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S554.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
NBPF10 MUTATED 7 3 2
NBPF10 WILD-TYPE 84 58 48
'NBPF10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S555.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
NBPF10 MUTATED 2 2 4 2 2
NBPF10 WILD-TYPE 34 29 54 33 35
'NBPF10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S556.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
NBPF10 MUTATED 5 5 2
NBPF10 WILD-TYPE 70 80 35
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S557.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
NBPF10 MUTATED 3 3 6
NBPF10 WILD-TYPE 45 73 67
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S558.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
NBPF10 MUTATED 1 2 4 2 3
NBPF10 WILD-TYPE 23 51 69 24 18
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S559.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
NBPF10 MUTATED 3 1 1 5 2
NBPF10 WILD-TYPE 23 33 39 55 35
'NBPF10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S560.  Gene #70: 'NBPF10 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
NBPF10 MUTATED 1 2 1 6 2
NBPF10 WILD-TYPE 22 44 34 65 20
'ZXDC MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S561.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ZXDC MUTATED 1 3 2
ZXDC WILD-TYPE 48 76 66
'ZXDC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 1

Table S562.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ZXDC MUTATED 5 1 0
ZXDC WILD-TYPE 86 60 50
'ZXDC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 1

Table S563.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ZXDC MUTATED 0 1 2 0 3
ZXDC WILD-TYPE 36 30 56 35 34
'ZXDC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.422 (Fisher's exact test), Q value = 1

Table S564.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ZXDC MUTATED 1 3 2
ZXDC WILD-TYPE 74 82 35
'ZXDC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00862 (Fisher's exact test), Q value = 1

Table S565.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ZXDC MUTATED 0 6 0
ZXDC WILD-TYPE 48 70 73

Figure S64.  Get High-res Image Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'ZXDC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0371 (Fisher's exact test), Q value = 1

Table S566.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ZXDC MUTATED 0 2 0 2 2
ZXDC WILD-TYPE 24 51 73 24 19

Figure S65.  Get High-res Image Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'ZXDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 1

Table S567.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ZXDC MUTATED 0 0 1 5 0
ZXDC WILD-TYPE 26 34 39 55 37
'ZXDC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0647 (Fisher's exact test), Q value = 1

Table S568.  Gene #71: 'ZXDC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ZXDC MUTATED 0 2 2 0 2
ZXDC WILD-TYPE 23 44 33 71 20
'TAS2R30 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S569.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
TAS2R30 MUTATED 2 3 3
TAS2R30 WILD-TYPE 47 76 65
'TAS2R30 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S570.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
TAS2R30 MUTATED 3 3 2
TAS2R30 WILD-TYPE 88 58 48
'TAS2R30 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S571.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
TAS2R30 MUTATED 2 1 1 3 1
TAS2R30 WILD-TYPE 34 30 57 32 36
'TAS2R30 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S572.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
TAS2R30 MUTATED 4 3 1
TAS2R30 WILD-TYPE 71 82 36
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S573.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
TAS2R30 MUTATED 1 3 4
TAS2R30 WILD-TYPE 47 73 69
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S574.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
TAS2R30 MUTATED 1 2 3 1 1
TAS2R30 WILD-TYPE 23 51 70 25 20
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S575.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
TAS2R30 MUTATED 3 0 2 1 2
TAS2R30 WILD-TYPE 23 34 38 59 35
'TAS2R30 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.978 (Fisher's exact test), Q value = 1

Table S576.  Gene #72: 'TAS2R30 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
TAS2R30 MUTATED 1 2 1 4 0
TAS2R30 WILD-TYPE 22 44 34 67 22
'KRTAP10-2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S577.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KRTAP10-2 MUTATED 2 1 4
KRTAP10-2 WILD-TYPE 47 78 64
'KRTAP10-2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S578.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KRTAP10-2 MUTATED 4 1 2
KRTAP10-2 WILD-TYPE 87 60 48
'KRTAP10-2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 1

Table S579.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KRTAP10-2 MUTATED 0 1 1 2 3
KRTAP10-2 WILD-TYPE 36 30 57 33 34
'KRTAP10-2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 1

Table S580.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KRTAP10-2 MUTATED 2 2 3
KRTAP10-2 WILD-TYPE 73 83 34
'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S581.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KRTAP10-2 MUTATED 2 3 2
KRTAP10-2 WILD-TYPE 46 73 71
'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0013 (Fisher's exact test), Q value = 1

Table S582.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KRTAP10-2 MUTATED 2 0 0 2 3
KRTAP10-2 WILD-TYPE 22 53 73 24 18

Figure S66.  Get High-res Image Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.103 (Fisher's exact test), Q value = 1

Table S583.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KRTAP10-2 MUTATED 3 0 1 3 0
KRTAP10-2 WILD-TYPE 23 34 39 57 37
'KRTAP10-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 1

Table S584.  Gene #73: 'KRTAP10-2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KRTAP10-2 MUTATED 2 0 1 2 2
KRTAP10-2 WILD-TYPE 21 46 34 69 20
'PPA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S585.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PPA2 MUTATED 0 2 2
PPA2 WILD-TYPE 49 77 66
'PPA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S586.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PPA2 MUTATED 3 1 0
PPA2 WILD-TYPE 88 60 50
'PPA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S587.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
PPA2 MUTATED 0 0 2 1 1
PPA2 WILD-TYPE 36 31 56 34 36
'PPA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S588.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
PPA2 MUTATED 1 2 1
PPA2 WILD-TYPE 74 83 36
'PPA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S589.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PPA2 MUTATED 1 2 1
PPA2 WILD-TYPE 47 74 72
'PPA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S590.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PPA2 MUTATED 0 2 1 0 1
PPA2 WILD-TYPE 24 51 72 26 20
'PPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 1

Table S591.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PPA2 MUTATED 1 0 0 3 0
PPA2 WILD-TYPE 25 34 40 57 37
'PPA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S592.  Gene #74: 'PPA2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PPA2 MUTATED 0 2 0 1 1
PPA2 WILD-TYPE 23 44 35 70 21
'SEPT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S593.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SEPT2 MUTATED 3 1 3
SEPT2 WILD-TYPE 46 78 65
'SEPT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 1

Table S594.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SEPT2 MUTATED 5 2 0
SEPT2 WILD-TYPE 86 59 50
'SEPT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S595.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SEPT2 MUTATED 1 2 1 0 2
SEPT2 WILD-TYPE 35 29 57 35 35
'SEPT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S596.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SEPT2 MUTATED 3 1 2
SEPT2 WILD-TYPE 72 84 35
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S597.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SEPT2 MUTATED 1 4 2
SEPT2 WILD-TYPE 47 72 71
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S598.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SEPT2 MUTATED 1 1 2 2 1
SEPT2 WILD-TYPE 23 52 71 24 20
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S599.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SEPT2 MUTATED 0 2 1 2 2
SEPT2 WILD-TYPE 26 32 39 58 35
'SEPT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S600.  Gene #75: 'SEPT2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SEPT2 MUTATED 0 1 3 2 1
SEPT2 WILD-TYPE 23 45 32 69 21
'DRD3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S601.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
DRD3 MUTATED 2 1 2
DRD3 WILD-TYPE 47 78 66
'DRD3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0726 (Fisher's exact test), Q value = 1

Table S602.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
DRD3 MUTATED 5 0 0
DRD3 WILD-TYPE 86 61 50
'DRD3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0385 (Fisher's exact test), Q value = 1

Table S603.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
DRD3 MUTATED 0 3 1 0 0
DRD3 WILD-TYPE 36 28 57 35 37

Figure S67.  Get High-res Image Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'DRD3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S604.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
DRD3 MUTATED 1 3 0
DRD3 WILD-TYPE 74 82 37
'DRD3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00703 (Fisher's exact test), Q value = 1

Table S605.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
DRD3 MUTATED 4 0 1
DRD3 WILD-TYPE 44 76 72

Figure S68.  Get High-res Image Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'DRD3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 1

Table S606.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
DRD3 MUTATED 2 1 1 1 0
DRD3 WILD-TYPE 22 52 72 25 21
'DRD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S607.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
DRD3 MUTATED 0 1 3 0 1
DRD3 WILD-TYPE 26 33 37 60 36
'DRD3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 1

Table S608.  Gene #76: 'DRD3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
DRD3 MUTATED 2 1 1 1 0
DRD3 WILD-TYPE 21 45 34 70 22
'PSRC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.562 (Fisher's exact test), Q value = 1

Table S609.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
PSRC1 MUTATED 2 1 1
PSRC1 WILD-TYPE 47 78 67
'PSRC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S610.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
PSRC1 MUTATED 3 0 1
PSRC1 WILD-TYPE 88 61 49
'PSRC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0418 (Fisher's exact test), Q value = 1

Table S611.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
PSRC1 MUTATED 3 0 1
PSRC1 WILD-TYPE 45 76 72

Figure S69.  Get High-res Image Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'PSRC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S612.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
PSRC1 MUTATED 1 1 1 1 0
PSRC1 WILD-TYPE 23 52 72 25 21
'PSRC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.319 (Fisher's exact test), Q value = 1

Table S613.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
PSRC1 MUTATED 0 1 2 0 1
PSRC1 WILD-TYPE 26 33 38 60 36
'PSRC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S614.  Gene #77: 'PSRC1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
PSRC1 MUTATED 1 1 1 1 0
PSRC1 WILD-TYPE 22 45 34 70 22
'KRTAP10-9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S615.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
KRTAP10-9 MUTATED 1 2 0
KRTAP10-9 WILD-TYPE 48 77 68
'KRTAP10-9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S616.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
KRTAP10-9 MUTATED 2 0 1
KRTAP10-9 WILD-TYPE 89 61 49
'KRTAP10-9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.349 (Fisher's exact test), Q value = 1

Table S617.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
KRTAP10-9 MUTATED 0 0 1 0 2
KRTAP10-9 WILD-TYPE 36 31 57 35 35
'KRTAP10-9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0915 (Fisher's exact test), Q value = 1

Table S618.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
KRTAP10-9 MUTATED 0 1 2
KRTAP10-9 WILD-TYPE 75 84 35
'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S619.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
KRTAP10-9 MUTATED 1 1 1
KRTAP10-9 WILD-TYPE 47 75 72
'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0432 (Fisher's exact test), Q value = 1

Table S620.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
KRTAP10-9 MUTATED 0 1 0 0 2
KRTAP10-9 WILD-TYPE 24 52 73 26 19

Figure S70.  Get High-res Image Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S621.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
KRTAP10-9 MUTATED 1 0 0 2 0
KRTAP10-9 WILD-TYPE 25 34 40 58 37
'KRTAP10-9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S622.  Gene #78: 'KRTAP10-9 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
KRTAP10-9 MUTATED 0 1 0 1 1
KRTAP10-9 WILD-TYPE 23 45 35 70 21
'SPATA12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S623.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SPATA12 MUTATED 2 2 2
SPATA12 WILD-TYPE 47 77 66
'SPATA12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S624.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SPATA12 MUTATED 3 2 1
SPATA12 WILD-TYPE 88 59 49
'SPATA12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S625.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SPATA12 MUTATED 1 0 2 2 1
SPATA12 WILD-TYPE 35 31 56 33 36
'SPATA12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S626.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SPATA12 MUTATED 2 3 1
SPATA12 WILD-TYPE 73 82 36
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S627.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SPATA12 MUTATED 2 3 1
SPATA12 WILD-TYPE 46 73 72
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S628.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SPATA12 MUTATED 1 2 2 0 1
SPATA12 WILD-TYPE 23 51 71 26 20
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S629.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SPATA12 MUTATED 1 0 2 2 1
SPATA12 WILD-TYPE 25 34 38 58 36
'SPATA12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S630.  Gene #79: 'SPATA12 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SPATA12 MUTATED 1 2 1 1 1
SPATA12 WILD-TYPE 22 44 34 70 21
'GPR112 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S631.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GPR112 MUTATED 5 4 5
GPR112 WILD-TYPE 44 75 63
'GPR112 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S632.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GPR112 MUTATED 9 4 2
GPR112 WILD-TYPE 82 57 48
'GPR112 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S633.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GPR112 MUTATED 1 4 3 3 3
GPR112 WILD-TYPE 35 27 55 32 34
'GPR112 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S634.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GPR112 MUTATED 7 4 3
GPR112 WILD-TYPE 68 81 34
'GPR112 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.488 (Fisher's exact test), Q value = 1

Table S635.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GPR112 MUTATED 3 8 4
GPR112 WILD-TYPE 45 68 69
'GPR112 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S636.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GPR112 MUTATED 0 4 7 1 3
GPR112 WILD-TYPE 24 49 66 25 18
'GPR112 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S637.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GPR112 MUTATED 0 1 2 7 5
GPR112 WILD-TYPE 26 33 38 53 32
'GPR112 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.181 (Fisher's exact test), Q value = 1

Table S638.  Gene #80: 'GPR112 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GPR112 MUTATED 0 5 4 3 3
GPR112 WILD-TYPE 23 41 31 68 19
'CLTCL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S639.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
CLTCL1 MUTATED 6 4 5
CLTCL1 WILD-TYPE 43 75 63
'CLTCL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S640.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
CLTCL1 MUTATED 10 3 3
CLTCL1 WILD-TYPE 81 58 47
'CLTCL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S641.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
CLTCL1 MUTATED 1 3 4 3 4
CLTCL1 WILD-TYPE 35 28 54 32 33
'CLTCL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S642.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
CLTCL1 MUTATED 6 5 4
CLTCL1 WILD-TYPE 69 80 33
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S643.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
CLTCL1 MUTATED 5 5 5
CLTCL1 WILD-TYPE 43 71 68
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0843 (Fisher's exact test), Q value = 1

Table S644.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
CLTCL1 MUTATED 3 1 5 2 4
CLTCL1 WILD-TYPE 21 52 68 24 17
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S645.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
CLTCL1 MUTATED 2 1 4 5 3
CLTCL1 WILD-TYPE 24 33 36 55 34
'CLTCL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 1

Table S646.  Gene #81: 'CLTCL1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
CLTCL1 MUTATED 3 1 3 5 3
CLTCL1 WILD-TYPE 20 45 32 66 19
'OR2A14 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S647.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR2A14 MUTATED 2 1 2
OR2A14 WILD-TYPE 47 78 66
'OR2A14 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 1

Table S648.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR2A14 MUTATED 4 0 1
OR2A14 WILD-TYPE 87 61 49
'OR2A14 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S649.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR2A14 MUTATED 0 0 2 1 1
OR2A14 WILD-TYPE 36 31 56 34 36
'OR2A14 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S650.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR2A14 MUTATED 1 2 1
OR2A14 WILD-TYPE 74 83 36
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S651.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR2A14 MUTATED 1 2 2
OR2A14 WILD-TYPE 47 74 71
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S652.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR2A14 MUTATED 1 0 3 0 1
OR2A14 WILD-TYPE 23 53 70 26 20
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S653.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR2A14 MUTATED 0 2 1 2 0
OR2A14 WILD-TYPE 26 32 39 58 37
'OR2A14 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S654.  Gene #82: 'OR2A14 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR2A14 MUTATED 1 0 1 2 1
OR2A14 WILD-TYPE 22 46 34 69 21
'OR4C16 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0925 (Fisher's exact test), Q value = 1

Table S655.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR4C16 MUTATED 3 4 0
OR4C16 WILD-TYPE 46 75 68
'OR4C16 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 1

Table S656.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR4C16 MUTATED 4 0 3
OR4C16 WILD-TYPE 87 61 47
'OR4C16 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0197 (Fisher's exact test), Q value = 1

Table S657.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR4C16 MUTATED 1 2 0 0 4
OR4C16 WILD-TYPE 35 29 58 35 33

Figure S71.  Get High-res Image Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'OR4C16 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0336 (Fisher's exact test), Q value = 1

Table S658.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR4C16 MUTATED 2 1 4
OR4C16 WILD-TYPE 73 84 33

Figure S72.  Get High-res Image Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'OR4C16 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S659.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR4C16 MUTATED 2 3 2
OR4C16 WILD-TYPE 46 73 71
'OR4C16 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00339 (Fisher's exact test), Q value = 1

Table S660.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR4C16 MUTATED 1 0 1 1 4
OR4C16 WILD-TYPE 23 53 72 25 17

Figure S73.  Get High-res Image Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'OR4C16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S661.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR4C16 MUTATED 1 0 1 3 2
OR4C16 WILD-TYPE 25 34 39 57 35
'OR4C16 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0788 (Fisher's exact test), Q value = 1

Table S662.  Gene #83: 'OR4C16 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR4C16 MUTATED 1 0 1 2 3
OR4C16 WILD-TYPE 22 46 34 69 19
'GBP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 1

Table S663.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GBP1 MUTATED 0 4 4
GBP1 WILD-TYPE 49 75 64
'GBP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.73 (Fisher's exact test), Q value = 1

Table S664.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GBP1 MUTATED 3 2 3
GBP1 WILD-TYPE 88 59 47
'GBP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S665.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GBP1 MUTATED 1 1 2 1 3
GBP1 WILD-TYPE 35 30 56 34 34
'GBP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.369 (Fisher's exact test), Q value = 1

Table S666.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GBP1 MUTATED 2 3 3
GBP1 WILD-TYPE 73 82 34
'GBP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S667.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GBP1 MUTATED 1 3 4
GBP1 WILD-TYPE 47 73 69
'GBP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S668.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GBP1 MUTATED 2 3 2 0 1
GBP1 WILD-TYPE 22 50 71 26 20
'GBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S669.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GBP1 MUTATED 2 1 1 2 2
GBP1 WILD-TYPE 24 33 39 58 35
'GBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S670.  Gene #84: 'GBP1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GBP1 MUTATED 2 2 2 2 0
GBP1 WILD-TYPE 21 44 33 69 22
'OR6B3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.736 (Fisher's exact test), Q value = 1

Table S671.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR6B3 MUTATED 2 2 1
OR6B3 WILD-TYPE 47 77 67
'OR6B3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.859 (Fisher's exact test), Q value = 1

Table S672.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR6B3 MUTATED 3 1 1
OR6B3 WILD-TYPE 88 60 49
'OR6B3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S673.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR6B3 MUTATED 0 1 1 1 2
OR6B3 WILD-TYPE 36 30 57 34 35
'OR6B3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 1

Table S674.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR6B3 MUTATED 1 2 2
OR6B3 WILD-TYPE 74 83 35
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 1

Table S675.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR6B3 MUTATED 1 4 0
OR6B3 WILD-TYPE 47 72 73
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 1

Table S676.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR6B3 MUTATED 1 1 1 0 2
OR6B3 WILD-TYPE 23 52 72 26 19
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S677.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR6B3 MUTATED 0 0 1 3 1
OR6B3 WILD-TYPE 26 34 39 57 36
'OR6B3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0763 (Fisher's exact test), Q value = 1

Table S678.  Gene #85: 'OR6B3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR6B3 MUTATED 1 1 1 0 2
OR6B3 WILD-TYPE 22 45 34 71 20
'OR2T27 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S679.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR2T27 MUTATED 3 3 4
OR2T27 WILD-TYPE 46 76 64
'OR2T27 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0109 (Fisher's exact test), Q value = 1

Table S680.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR2T27 MUTATED 9 1 0
OR2T27 WILD-TYPE 82 60 50

Figure S74.  Get High-res Image Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'OR2T27 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 1

Table S681.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR2T27 MUTATED 0 3 2 1 3
OR2T27 WILD-TYPE 36 28 56 34 34
'OR2T27 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S682.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR2T27 MUTATED 3 3 3
OR2T27 WILD-TYPE 72 82 34
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.354 (Fisher's exact test), Q value = 1

Table S683.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR2T27 MUTATED 2 6 2
OR2T27 WILD-TYPE 46 70 71
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.162 (Fisher's exact test), Q value = 1

Table S684.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR2T27 MUTATED 0 3 2 2 3
OR2T27 WILD-TYPE 24 50 71 24 18
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S685.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR2T27 MUTATED 1 1 1 6 1
OR2T27 WILD-TYPE 25 33 39 54 36
'OR2T27 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 1

Table S686.  Gene #86: 'OR2T27 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR2T27 MUTATED 0 3 2 2 3
OR2T27 WILD-TYPE 23 43 33 69 19
'RAET1E MUTATION STATUS' versus 'CN_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S687.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
RAET1E MUTATED 1 3 1
RAET1E WILD-TYPE 48 76 67
'RAET1E MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.323 (Fisher's exact test), Q value = 1

Table S688.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
RAET1E MUTATED 3 0 2
RAET1E WILD-TYPE 88 61 48
'RAET1E MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 1

Table S689.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
RAET1E MUTATED 0 1 1 0 3
RAET1E WILD-TYPE 36 30 57 35 34
'RAET1E MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0332 (Fisher's exact test), Q value = 1

Table S690.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
RAET1E MUTATED 0 2 3
RAET1E WILD-TYPE 75 83 34

Figure S75.  Get High-res Image Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'RAET1E MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S691.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
RAET1E MUTATED 2 2 1
RAET1E WILD-TYPE 46 74 72
'RAET1E MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0187 (Fisher's exact test), Q value = 1

Table S692.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
RAET1E MUTATED 2 1 0 0 2
RAET1E WILD-TYPE 22 52 73 26 19

Figure S76.  Get High-res Image Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'RAET1E MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S693.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
RAET1E MUTATED 1 0 2 2 0
RAET1E WILD-TYPE 25 34 38 58 37
'RAET1E MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 1

Table S694.  Gene #87: 'RAET1E MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
RAET1E MUTATED 2 1 0 1 1
RAET1E WILD-TYPE 21 45 35 70 21
'SHROOM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S695.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SHROOM1 MUTATED 2 1 2
SHROOM1 WILD-TYPE 47 78 66
'SHROOM1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S696.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SHROOM1 MUTATED 3 1 1
SHROOM1 WILD-TYPE 88 60 49
'SHROOM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S697.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SHROOM1 MUTATED 1 1 1 1 1
SHROOM1 WILD-TYPE 35 30 57 34 36
'SHROOM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S698.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SHROOM1 MUTATED 2 2 1
SHROOM1 WILD-TYPE 73 83 36
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S699.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SHROOM1 MUTATED 1 2 2
SHROOM1 WILD-TYPE 47 74 71
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.26 (Fisher's exact test), Q value = 1

Table S700.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SHROOM1 MUTATED 2 1 1 0 1
SHROOM1 WILD-TYPE 22 52 72 26 20
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S701.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SHROOM1 MUTATED 1 1 1 2 0
SHROOM1 WILD-TYPE 25 33 39 58 37
'SHROOM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0773 (Fisher's exact test), Q value = 1

Table S702.  Gene #88: 'SHROOM1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SHROOM1 MUTATED 2 1 1 0 1
SHROOM1 WILD-TYPE 21 45 34 71 21
'OR52I2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S703.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR52I2 MUTATED 1 2 3
OR52I2 WILD-TYPE 48 77 65
'OR52I2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S704.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR52I2 MUTATED 3 2 1
OR52I2 WILD-TYPE 88 59 49
'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 1

Table S705.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR52I2 MUTATED 0 1 1 1 3
OR52I2 WILD-TYPE 36 30 57 34 34
'OR52I2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.164 (Fisher's exact test), Q value = 1

Table S706.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR52I2 MUTATED 1 2 3
OR52I2 WILD-TYPE 74 83 34
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S707.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR52I2 MUTATED 2 2 2
OR52I2 WILD-TYPE 46 74 71
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.048 (Fisher's exact test), Q value = 1

Table S708.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR52I2 MUTATED 1 1 1 0 3
OR52I2 WILD-TYPE 23 52 72 26 18

Figure S77.  Get High-res Image Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 1

Table S709.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR52I2 MUTATED 2 0 1 3 0
OR52I2 WILD-TYPE 24 34 39 57 37
'OR52I2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S710.  Gene #89: 'OR52I2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR52I2 MUTATED 1 1 0 2 2
OR52I2 WILD-TYPE 22 45 35 69 20
'OR13C2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S711.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
OR13C2 MUTATED 2 0 2
OR13C2 WILD-TYPE 47 79 66
'OR13C2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 1

Table S712.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
OR13C2 MUTATED 1 3 0
OR13C2 WILD-TYPE 90 58 50
'OR13C2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0849 (Fisher's exact test), Q value = 1

Table S713.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
OR13C2 MUTATED 0 0 0 2 2
OR13C2 WILD-TYPE 36 31 58 33 35
'OR13C2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0706 (Fisher's exact test), Q value = 1

Table S714.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
OR13C2 MUTATED 2 0 2
OR13C2 WILD-TYPE 73 85 35
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S715.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
OR13C2 MUTATED 0 3 1
OR13C2 WILD-TYPE 48 73 72
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.136 (Fisher's exact test), Q value = 1

Table S716.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
OR13C2 MUTATED 0 0 2 0 2
OR13C2 WILD-TYPE 24 53 71 26 19
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S717.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
OR13C2 MUTATED 1 0 0 2 1
OR13C2 WILD-TYPE 25 34 40 58 36
'OR13C2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.138 (Fisher's exact test), Q value = 1

Table S718.  Gene #90: 'OR13C2 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
OR13C2 MUTATED 0 0 1 1 2
OR13C2 WILD-TYPE 23 46 34 70 20
'LIPC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S719.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
LIPC MUTATED 2 2 2
LIPC WILD-TYPE 47 77 66
'LIPC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S720.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
LIPC MUTATED 3 2 1
LIPC WILD-TYPE 88 59 49
'LIPC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 1

Table S721.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
LIPC MUTATED 0 0 3 3 0
LIPC WILD-TYPE 36 31 55 32 37
'LIPC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S722.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
LIPC MUTATED 3 3 0
LIPC WILD-TYPE 72 82 37
'LIPC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 1

Table S723.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
LIPC MUTATED 0 4 2
LIPC WILD-TYPE 48 72 71
'LIPC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.969 (Fisher's exact test), Q value = 1

Table S724.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
LIPC MUTATED 0 2 3 1 0
LIPC WILD-TYPE 24 51 70 25 21
'LIPC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S725.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
LIPC MUTATED 1 0 0 4 1
LIPC WILD-TYPE 25 34 40 56 36
'LIPC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.972 (Fisher's exact test), Q value = 1

Table S726.  Gene #91: 'LIPC MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
LIPC MUTATED 0 2 1 3 0
LIPC WILD-TYPE 23 44 34 68 22
'FAM22F MUTATION STATUS' versus 'CN_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 1

Table S727.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
FAM22F MUTATED 2 0 2
FAM22F WILD-TYPE 47 79 66
'FAM22F MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0114 (Fisher's exact test), Q value = 1

Table S728.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
FAM22F MUTATED 0 4 0
FAM22F WILD-TYPE 91 57 50

Figure S78.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'FAM22F MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0342 (Fisher's exact test), Q value = 1

Table S729.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
FAM22F MUTATED 3 0 0 1 0
FAM22F WILD-TYPE 33 31 58 34 37

Figure S79.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

'FAM22F MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0413 (Fisher's exact test), Q value = 1

Table S730.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
FAM22F MUTATED 4 0 0
FAM22F WILD-TYPE 71 85 37

Figure S80.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'FAM22F MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.18 (Fisher's exact test), Q value = 1

Table S731.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
FAM22F MUTATED 1 0 3
FAM22F WILD-TYPE 47 76 70
'FAM22F MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S732.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
FAM22F MUTATED 0 1 3 0 0
FAM22F WILD-TYPE 24 52 70 26 21
'FAM22F MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00101 (Fisher's exact test), Q value = 0.8

Table S733.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
FAM22F MUTATED 0 4 0 0 0
FAM22F WILD-TYPE 26 30 40 60 37

Figure S81.  Get High-res Image Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

'FAM22F MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 1

Table S734.  Gene #92: 'FAM22F MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
FAM22F MUTATED 0 0 0 4 0
FAM22F WILD-TYPE 23 46 35 67 22
'GLRX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 1

Table S735.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
GLRX3 MUTATED 1 3 0
GLRX3 WILD-TYPE 48 76 68
'GLRX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S736.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
GLRX3 MUTATED 3 0 1
GLRX3 WILD-TYPE 88 61 49
'GLRX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.114 (Fisher's exact test), Q value = 1

Table S737.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
GLRX3 MUTATED 0 0 1 0 3
GLRX3 WILD-TYPE 36 31 57 35 34
'GLRX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0213 (Fisher's exact test), Q value = 1

Table S738.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
GLRX3 MUTATED 0 1 3
GLRX3 WILD-TYPE 75 84 34

Figure S82.  Get High-res Image Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

'GLRX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S739.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
GLRX3 MUTATED 0 3 1
GLRX3 WILD-TYPE 48 73 72
'GLRX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00792 (Fisher's exact test), Q value = 1

Table S740.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
GLRX3 MUTATED 0 1 0 0 3
GLRX3 WILD-TYPE 24 52 73 26 18

Figure S83.  Get High-res Image Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

'GLRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 1

Table S741.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
GLRX3 MUTATED 1 0 0 3 0
GLRX3 WILD-TYPE 25 34 40 57 37
'GLRX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.201 (Fisher's exact test), Q value = 1

Table S742.  Gene #93: 'GLRX3 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
GLRX3 MUTATED 0 1 0 1 2
GLRX3 WILD-TYPE 23 45 35 70 20
'HOXA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S743.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
HOXA4 MUTATED 1 3 1
HOXA4 WILD-TYPE 48 76 67
'HOXA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S744.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
HOXA4 MUTATED 4 1 0
HOXA4 WILD-TYPE 87 60 50
'HOXA4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S745.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
HOXA4 MUTATED 1 1 2 0 1
HOXA4 WILD-TYPE 35 30 56 35 36
'HOXA4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S746.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
HOXA4 MUTATED 1 3 1
HOXA4 WILD-TYPE 74 82 36
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 1

Table S747.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
HOXA4 MUTATED 3 1 1
HOXA4 WILD-TYPE 45 75 72
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0847 (Fisher's exact test), Q value = 1

Table S748.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
HOXA4 MUTATED 2 2 0 0 1
HOXA4 WILD-TYPE 22 51 73 26 20
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S749.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
HOXA4 MUTATED 0 2 2 1 0
HOXA4 WILD-TYPE 26 32 38 59 37
'HOXA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.206 (Fisher's exact test), Q value = 1

Table S750.  Gene #94: 'HOXA4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
HOXA4 MUTATED 2 1 0 1 1
HOXA4 WILD-TYPE 21 45 35 70 21
'DENND4B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S751.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
DENND4B MUTATED 2 2 5
DENND4B WILD-TYPE 47 77 63
'DENND4B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 1

Table S752.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
DENND4B MUTATED 7 1 1
DENND4B WILD-TYPE 84 60 49
'DENND4B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0519 (Fisher's exact test), Q value = 1

Table S753.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
DENND4B MUTATED 0 4 3 1 0
DENND4B WILD-TYPE 36 27 55 34 37
'DENND4B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.217 (Fisher's exact test), Q value = 1

Table S754.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
DENND4B MUTATED 2 6 0
DENND4B WILD-TYPE 73 79 37
'DENND4B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S755.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
DENND4B MUTATED 4 3 2
DENND4B WILD-TYPE 44 73 71
'DENND4B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.223 (Fisher's exact test), Q value = 1

Table S756.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
DENND4B MUTATED 3 1 4 0 1
DENND4B WILD-TYPE 21 52 69 26 20
'DENND4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S757.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
DENND4B MUTATED 0 1 4 3 1
DENND4B WILD-TYPE 26 33 36 57 36
'DENND4B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S758.  Gene #95: 'DENND4B MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
DENND4B MUTATED 3 1 1 3 1
DENND4B WILD-TYPE 20 45 34 68 21
'ESX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S759.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
ESX1 MUTATED 2 2 2
ESX1 WILD-TYPE 47 77 66
'ESX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S760.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
ESX1 MUTATED 4 1 1
ESX1 WILD-TYPE 87 60 49
'ESX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 1

Table S761.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
ESX1 MUTATED 1 3 2 0 0
ESX1 WILD-TYPE 35 28 56 35 37
'ESX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 1

Table S762.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
ESX1 MUTATED 1 5 0
ESX1 WILD-TYPE 74 80 37
'ESX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S763.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
ESX1 MUTATED 1 2 3
ESX1 WILD-TYPE 47 74 70
'ESX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.256 (Fisher's exact test), Q value = 1

Table S764.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
ESX1 MUTATED 1 4 1 0 0
ESX1 WILD-TYPE 23 49 72 26 21
'ESX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.128 (Fisher's exact test), Q value = 1

Table S765.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
ESX1 MUTATED 0 1 3 0 2
ESX1 WILD-TYPE 26 33 37 60 35
'ESX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.135 (Fisher's exact test), Q value = 1

Table S766.  Gene #96: 'ESX1 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
ESX1 MUTATED 1 4 0 1 0
ESX1 WILD-TYPE 22 42 35 70 22
'SLFN12L MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S767.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
SLFN12L MUTATED 1 3 2
SLFN12L WILD-TYPE 48 76 66
'SLFN12L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.282 (Fisher's exact test), Q value = 1

Table S768.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
SLFN12L MUTATED 4 0 2
SLFN12L WILD-TYPE 87 61 48
'SLFN12L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S769.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
SLFN12L MUTATED 2 1 2 0 0
SLFN12L WILD-TYPE 34 30 56 35 37
'SLFN12L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S770.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
SLFN12L MUTATED 2 3 0
SLFN12L WILD-TYPE 73 82 37
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S771.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
SLFN12L MUTATED 1 2 3
SLFN12L WILD-TYPE 47 74 70
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.813 (Fisher's exact test), Q value = 1

Table S772.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
SLFN12L MUTATED 0 1 3 1 1
SLFN12L WILD-TYPE 24 52 70 25 20
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S773.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
SLFN12L MUTATED 0 2 0 2 2
SLFN12L WILD-TYPE 26 32 40 58 35
'SLFN12L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S774.  Gene #97: 'SLFN12L MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
SLFN12L MUTATED 0 1 1 3 1
SLFN12L WILD-TYPE 23 45 34 68 21
'FKBP4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.534 (Fisher's exact test), Q value = 1

Table S775.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
FKBP4 MUTATED 1 1 3
FKBP4 WILD-TYPE 48 78 65
'FKBP4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S776.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
FKBP4 MUTATED 4 1 0
FKBP4 WILD-TYPE 87 60 50
'FKBP4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 1

Table S777.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
FKBP4 MUTATED 0 2 1 0 1
FKBP4 WILD-TYPE 36 29 57 35 36
'FKBP4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.247 (Fisher's exact test), Q value = 1

Table S778.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
FKBP4 MUTATED 0 3 1
FKBP4 WILD-TYPE 75 82 36
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S779.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
FKBP4 MUTATED 1 3 1
FKBP4 WILD-TYPE 47 73 72
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S780.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
FKBP4 MUTATED 1 2 1 0 1
FKBP4 WILD-TYPE 23 51 72 26 20
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 1

Table S781.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
FKBP4 MUTATED 0 1 3 1 0
FKBP4 WILD-TYPE 26 33 37 59 37
'FKBP4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S782.  Gene #98: 'FKBP4 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
FKBP4 MUTATED 1 2 0 1 1
FKBP4 WILD-TYPE 22 44 35 70 21
'AQP7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.911 (Fisher's exact test), Q value = 1

Table S783.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
AQP7 MUTATED 2 3 4
AQP7 WILD-TYPE 47 76 64
'AQP7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0226 (Fisher's exact test), Q value = 1

Table S784.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
AQP7 MUTATED 8 1 0
AQP7 WILD-TYPE 83 60 50

Figure S84.  Get High-res Image Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

'AQP7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 1

Table S785.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
AQP7 MUTATED 0 0 5 1 3
AQP7 WILD-TYPE 36 31 53 34 34
'AQP7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S786.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
AQP7 MUTATED 2 4 3
AQP7 WILD-TYPE 73 81 34
'AQP7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 1

Table S787.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
AQP7 MUTATED 0 5 2
AQP7 WILD-TYPE 48 71 71
'AQP7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 1

Table S788.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
AQP7 MUTATED 1 3 1 0 2
AQP7 WILD-TYPE 23 50 72 26 19
'AQP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S789.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
AQP7 MUTATED 1 1 1 4 0
AQP7 WILD-TYPE 25 33 39 56 37
'AQP7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 1

Table S790.  Gene #99: 'AQP7 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
AQP7 MUTATED 1 3 0 1 2
AQP7 WILD-TYPE 22 43 35 70 20
'MAP4K5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S791.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
MAP4K5 MUTATED 1 6 3
MAP4K5 WILD-TYPE 48 73 65
'MAP4K5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S792.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
MAP4K5 MUTATED 4 3 3
MAP4K5 WILD-TYPE 87 58 47
'MAP4K5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S793.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
MAP4K5 MUTATED 2 3 1 2 2
MAP4K5 WILD-TYPE 34 28 57 33 35
'MAP4K5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S794.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
MAP4K5 MUTATED 4 4 2
MAP4K5 WILD-TYPE 71 81 35
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S795.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
MAP4K5 MUTATED 2 4 4
MAP4K5 WILD-TYPE 46 72 69
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.373 (Fisher's exact test), Q value = 1

Table S796.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
MAP4K5 MUTATED 2 1 3 2 2
MAP4K5 WILD-TYPE 22 52 70 24 19
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.607 (Fisher's exact test), Q value = 1

Table S797.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
MAP4K5 MUTATED 3 1 2 2 2
MAP4K5 WILD-TYPE 23 33 38 58 35
'MAP4K5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S798.  Gene #100: 'MAP4K5 MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
MAP4K5 MUTATED 2 1 1 5 1
MAP4K5 WILD-TYPE 21 45 34 66 21
'BCL11A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S799.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #1: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 49 79 68
BCL11A MUTATED 2 2 3
BCL11A WILD-TYPE 47 77 65
'BCL11A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S800.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #2: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 91 61 50
BCL11A MUTATED 3 1 3
BCL11A WILD-TYPE 88 60 47
'BCL11A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S801.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #3: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 36 31 58 35 37
BCL11A MUTATED 2 1 2 0 1
BCL11A WILD-TYPE 34 30 56 35 36
'BCL11A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0733 (Fisher's exact test), Q value = 1

Table S802.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 75 85 37
BCL11A MUTATED 0 5 1
BCL11A WILD-TYPE 75 80 36
'BCL11A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00489 (Fisher's exact test), Q value = 1

Table S803.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 48 76 73
BCL11A MUTATED 5 0 2
BCL11A WILD-TYPE 43 76 71

Figure S85.  Get High-res Image Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #5: 'MIRSEQ_CNMF'

'BCL11A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 1

Table S804.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 24 53 73 26 21
BCL11A MUTATED 3 2 2 0 0
BCL11A WILD-TYPE 21 51 71 26 21
'BCL11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 1

Table S805.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 26 34 40 60 37
BCL11A MUTATED 1 2 3 1 0
BCL11A WILD-TYPE 25 32 37 59 37
'BCL11A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 1

Table S806.  Gene #101: 'BCL11A MUTATION STATUS' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 23 46 35 71 22
BCL11A MUTATED 3 1 0 3 0
BCL11A WILD-TYPE 20 45 35 68 22
Methods & Data
Input

  • Mutation data file = transformed.cor.cli.txt

  • Molecular subtypes file = LIHC-TP.transferedmergedcluster.txt

  • Number of patients = 202

  • Number of significantly mutated genes = 101

  • Number of Molecular subtypes = 8

  • Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References
[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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