Association of mutation, copy number alteration, and subtype markers with pathways
Breast Invasive Carcinoma (Primary solid tumor)
17 October 2014  |  analyses__2014_10_17
Maintainer Information
Citation Information
doi:10.7908/C1V69HFB
Maintained by Spring Yingchun Liu (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2014): Association of mutation, copy number alteration, and subtype markers with pathways. Broad Institute of MIT and Harvard. doi:10.7908/C1V69HFB
- Overview
+ Introduction
- Summary

There are 94 genes with significant mutation (Q value <= 0.1) and 173 genes with significant copy number alteration (Q value <= 0.25). The identified marker genes (Q value <= 0.01 or within top 2000) are 2000 for subtype 1, 2000 for subtype 2, 2000 for subtype 3, 2000 for subtype 4, 2000 for subtype 5, 2000 for subtype 6. Pathways significantly enriched with these genes (Q value <= 0.01) are identified :

43 pathways significantly enriched with genes with copy number alteration or mutation.

0 pathways significantly enriched with marker genes of gene expression subtype 1

0 pathways significantly enriched with marker genes of gene expression subtype 2

0 pathways significantly enriched with marker genes of gene expression subtype 3

0 pathways significantly enriched with marker genes of gene expression subtype 4

0 pathways significantly enriched with marker genes of gene expression subtype 5

0 pathways significantly enriched with marker genes of gene expression subtype 6

- Results
+ The top five pathways enriched with genes with copy number alteration or mutation
+ The top five pathways enriched with marker genes of gene expression subtype 1
+ The top five pathways enriched with marker genes of gene expression subtype 2
+ The top five pathways enriched with marker genes of gene expression subtype 3
+ The top five pathways enriched with marker genes of gene expression subtype 4
+ The top five pathways enriched with marker genes of gene expression subtype 5
+ The top five pathways enriched with marker genes of gene expression subtype 6
+ Methods & Data
Copyright © 2015 Broad Institute TCGA GDAC as part of the TCGA Research Network. All rights reserved.
Made with Nozzle