Clustering of mRNAseq gene expression: consensus hierarchical
Lung Squamous Cell Carcinoma (Primary solid tumor)
17 October 2014  |  analyses__2014_10_17
Maintainer Information
Citation Information
Maintained by Hailei Zhang (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2014): Clustering of mRNAseq gene expression: consensus hierarchical. Broad Institute of MIT and Harvard. doi:10.7908/C1C53JRT
- Overview
+ Introduction
- Summary

Median absolute deviation (MAD) was used to select 1500 most variable genes. Consensus ward linkage hierarchical clustering of 501 samples and 1500 genes identified 3 subtypes with the stability of the clustering increasing for k = 2 to k = 10.

- Results
+ Gene expression patterns of molecular subtypes
+ Silhouette widths, Cophenetic Correlation Coefficients and Consensus matrix
+ Samples assignment with silhouette width
+ Marker genes of each subtype
+ Methods & Data