Clustering of miR expression: consensus hierarchical
Ovarian Serous Cystadenocarcinoma (Primary solid tumor)
17 October 2014
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analyses__2014_10_17
Maintainer Information
Citation Information
Maintained by Hailei Zhang
(Broad Institute)
Cite as
Broad Institute TCGA Genome Data Analysis Center
(2014):
Clustering of miR expression: consensus hierarchical.
Broad Institute of MIT and Harvard.
doi:10.7908/C19W0DD5
Overview
Introduction
Summary
Median absolute deviation (MAD) was used to select 205 most variable miRs. Consensus ward linkage hierarchical clustering of 568 samples and 205 miRs identified 10 subtypes with the stability of the clustering increasing for k = 2 to k = 10.
Results
miR expression patterns of molecular subtypes
Silhouette widths, Cophenetic Correlation Coefficients and Consensus matrix
Samples assignment with silhouette width
Marker miRs of each subtype
Methods & Data
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Broad Institute TCGA GDAC as part of the TCGA Research Network.
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