This pipeline computes the correlation between significant copy number variation (cnv focal) genes and molecular subtypes.
Testing the association between copy number variation 69 focal events and 10 molecular subtypes across 408 patients, 328 significant findings detected with P value < 0.05 and Q value < 0.25.
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amp_1p34.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_1q21.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_1q23.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_2p25.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_3p25.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_3q26.33 cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_4p16.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_4q13.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_5p15.33 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_6p22.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_6q21 cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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amp_6q23.3 cnv correlated to 'CN_CNMF'.
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amp_7p21.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_7p11.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_8p11.23 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CNMF'.
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amp_8p11.21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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amp_8q22.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_9p24.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_10p14 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_11p13 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_11q13.3 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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amp_11q22.2 cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_12p12.1 cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_12q15 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_13q22.1 cnv correlated to 'CN_CNMF'.
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amp_16p13.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_16q22.1 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_17q12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_17q23.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_19q12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_19q13.43 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_20q11.21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_22q12.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_1p36.11 cnv correlated to 'RPPA_CHIERARCHICAL' and 'MIRSEQ_CHIERARCHICAL'.
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del_1q32.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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del_2q22.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_2q34 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_2q37.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_3p14.2 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_4q22.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_4q34.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_5q12.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_6p25.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_6q21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_6q27 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_7q36.3 cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_8p23.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_8p21.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_9p23 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_9p21.3 cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_9q22.33 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_10p11.21 cnv correlated to 'MRNASEQ_CNMF'.
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del_10q23.31 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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del_11p15.5 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_11q23.3 cnv correlated to 'CN_CNMF'.
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del_11q25 cnv correlated to 'CN_CNMF'.
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del_12p13.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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del_12q24.33 cnv correlated to 'CN_CNMF'.
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del_13q14.2 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_14q24.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_15q13.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_16p13.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_16q23.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_17p12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_18q23 cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_19p13.3 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_22q13.32 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_xp11.3 cnv correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_xq21.33 cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 69 focal events and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 328 significant findings detected.
|
Clinical Features |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| amp 3p25 2 | 190 (47%) | 218 |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.0782 (0.148) |
0.0109 (0.0335) |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.00015 (0.000877) |
4e-05 (0.000294) |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
| amp 17q12 | 166 (41%) | 242 |
1e-05 (9.32e-05) |
0.0013 (0.00579) |
0.0777 (0.148) |
0.0205 (0.0539) |
0.0017 (0.0072) |
0.0248 (0.0609) |
0.00365 (0.0141) |
0.0293 (0.0693) |
0.0105 (0.0326) |
1e-05 (9.32e-05) |
| del 9q22 33 | 178 (44%) | 230 |
2e-05 (0.00017) |
1e-05 (9.32e-05) |
0.0745 (0.142) |
0.00596 (0.0213) |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.00845 (0.0278) |
9e-05 (0.000559) |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
| amp 4p16 3 | 73 (18%) | 335 |
0.0462 (0.099) |
0.021 (0.055) |
0.0607 (0.122) |
0.0499 (0.105) |
0.00033 (0.00175) |
0.00015 (0.000877) |
2e-05 (0.00017) |
0.0338 (0.078) |
0.0561 (0.116) |
0.0262 (0.0629) |
| amp 12q15 | 118 (29%) | 290 |
0.00103 (0.00477) |
0.138 (0.235) |
0.0381 (0.0857) |
0.0199 (0.0529) |
0.0043 (0.0162) |
0.00856 (0.028) |
0.214 (0.324) |
0.0205 (0.0539) |
0.00751 (0.0255) |
0.0005 (0.00256) |
| del 3p14 2 | 117 (29%) | 291 |
0.00031 (0.00166) |
0.152 (0.25) |
0.0347 (0.0799) |
0.017 (0.0474) |
1e-05 (9.32e-05) |
6e-05 (0.00041) |
0.881 (0.908) |
2e-05 (0.00017) |
0.0001 (0.000616) |
3e-05 (0.00023) |
| del 9p23 | 178 (44%) | 230 |
1e-05 (9.32e-05) |
0.00026 (0.00144) |
0.252 (0.366) |
0.131 (0.226) |
0.0244 (0.0605) |
0.00024 (0.00135) |
0.0445 (0.0962) |
0.0146 (0.0418) |
1e-05 (9.32e-05) |
0.00045 (0.00237) |
| del 13q14 2 | 156 (38%) | 252 |
1e-05 (9.32e-05) |
0.204 (0.313) |
0.00754 (0.0255) |
0.00337 (0.0132) |
0.0223 (0.057) |
0.0108 (0.0333) |
0.536 (0.635) |
0.00025 (0.00139) |
0.00583 (0.0212) |
1e-05 (9.32e-05) |
| del 14q24 1 | 137 (34%) | 271 |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.39 (0.507) |
0.346 (0.466) |
0.00662 (0.0231) |
1e-05 (9.32e-05) |
0.00666 (0.0231) |
0.00075 (0.00359) |
0.00356 (0.0139) |
2e-05 (0.00017) |
| del 22q13 32 | 187 (46%) | 221 |
1e-05 (9.32e-05) |
0.0008 (0.00378) |
0.552 (0.645) |
0.0162 (0.0456) |
0.0412 (0.0923) |
0.00188 (0.00768) |
0.289 (0.407) |
0.0017 (0.0072) |
0.0102 (0.0319) |
1e-05 (9.32e-05) |
| amp 1q23 3 | 216 (53%) | 192 |
1e-05 (9.32e-05) |
0.0111 (0.0338) |
0.551 (0.645) |
0.886 (0.911) |
0.159 (0.259) |
0.0259 (0.0625) |
0.00175 (0.00736) |
0.00307 (0.0122) |
0.0421 (0.0923) |
0.00142 (0.0062) |
| amp 9p24 1 | 88 (22%) | 320 |
1e-05 (9.32e-05) |
0.00067 (0.00335) |
0.67 (0.739) |
0.324 (0.443) |
0.0265 (0.0636) |
0.00184 (0.00756) |
0.69 (0.757) |
0.0435 (0.0945) |
7e-05 (0.00046) |
0.00011 (0.000672) |
| amp 16q22 1 | 108 (26%) | 300 |
4e-05 (0.000294) |
0.459 (0.572) |
0.0425 (0.0926) |
0.023 (0.0576) |
0.189 (0.294) |
0.00461 (0.0172) |
0.042 (0.0923) |
0.00864 (0.0281) |
0.153 (0.25) |
0.0065 (0.0228) |
| del 11p15 5 | 211 (52%) | 197 |
1e-05 (9.32e-05) |
0.00016 (0.000928) |
0.369 (0.486) |
0.243 (0.359) |
0.00166 (0.00711) |
1e-05 (9.32e-05) |
0.0215 (0.0561) |
0.3 (0.418) |
0.0135 (0.0395) |
0.0125 (0.0371) |
| amp 5p15 33 | 205 (50%) | 203 |
1e-05 (9.32e-05) |
0.00732 (0.025) |
0.0236 (0.0588) |
0.186 (0.29) |
0.411 (0.529) |
0.0178 (0.0486) |
0.488 (0.597) |
2e-05 (0.00017) |
0.319 (0.438) |
0.0011 (0.00503) |
| amp 8q22 3 | 264 (65%) | 144 |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.0249 (0.0609) |
0.192 (0.297) |
0.334 (0.453) |
0.254 (0.368) |
0.0184 (0.0497) |
0.00594 (0.0213) |
0.0696 (0.135) |
0.00015 (0.000877) |
| amp 11p13 | 51 (12%) | 357 |
1e-05 (9.32e-05) |
0.00489 (0.0179) |
0.0334 (0.0778) |
0.00374 (0.0143) |
0.0596 (0.121) |
0.00064 (0.00322) |
0.251 (0.365) |
0.121 (0.212) |
0.0521 (0.109) |
0.00327 (0.0129) |
| amp 20q11 21 | 262 (64%) | 146 |
1e-05 (9.32e-05) |
0.0078 (0.0259) |
0.737 (0.793) |
0.0319 (0.0749) |
0.66 (0.731) |
0.0421 (0.0923) |
0.455 (0.571) |
0.0416 (0.0923) |
0.317 (0.437) |
0.0011 (0.00503) |
| del 2q37 1 | 208 (51%) | 200 |
1e-05 (9.32e-05) |
6e-05 (0.00041) |
0.495 (0.599) |
0.407 (0.523) |
0.0606 (0.122) |
0.0486 (0.103) |
0.0138 (0.04) |
0.0452 (0.0975) |
0.141 (0.237) |
0.00438 (0.0164) |
| del 4q22 1 | 162 (40%) | 246 |
1e-05 (9.32e-05) |
0.062 (0.124) |
0.506 (0.607) |
0.503 (0.605) |
0.0218 (0.0565) |
0.00102 (0.00477) |
0.896 (0.918) |
0.00764 (0.0256) |
0.0248 (0.0609) |
0.0144 (0.0417) |
| del 5q12 1 | 202 (50%) | 206 |
1e-05 (9.32e-05) |
7e-05 (0.00046) |
0.935 (0.949) |
0.573 (0.662) |
0.653 (0.726) |
0.00489 (0.0179) |
0.0217 (0.0564) |
9e-05 (0.000559) |
0.0602 (0.122) |
0.00115 (0.00515) |
| del 6q27 | 190 (47%) | 218 |
1e-05 (9.32e-05) |
0.027 (0.0644) |
0.66 (0.731) |
0.436 (0.553) |
0.536 (0.635) |
0.0101 (0.0317) |
0.0228 (0.0575) |
6e-05 (0.00041) |
0.375 (0.491) |
1e-05 (9.32e-05) |
| del 8p21 3 | 252 (62%) | 156 |
1e-05 (9.32e-05) |
2e-05 (0.00017) |
0.61 (0.69) |
0.0673 (0.131) |
0.493 (0.598) |
0.00908 (0.0291) |
0.0174 (0.048) |
0.00831 (0.0274) |
0.148 (0.245) |
0.0008 (0.00378) |
| del 9p21 3 | 239 (59%) | 169 |
1e-05 (9.32e-05) |
0.298 (0.417) |
0.451 (0.566) |
0.0101 (0.0317) |
0.0371 (0.0842) |
0.0223 (0.057) |
0.152 (0.25) |
0.0959 (0.176) |
0.0373 (0.0844) |
6e-05 (0.00041) |
| del 15q13 1 | 160 (39%) | 248 |
1e-05 (9.32e-05) |
6e-05 (0.00041) |
0.321 (0.439) |
0.678 (0.747) |
0.629 (0.703) |
0.357 (0.475) |
0.015 (0.0427) |
8e-05 (0.000506) |
0.0125 (0.0371) |
3e-05 (0.00023) |
| amp 1p34 2 | 101 (25%) | 307 |
1e-05 (9.32e-05) |
0.0003 (0.00162) |
0.185 (0.29) |
0.508 (0.609) |
0.876 (0.904) |
0.0952 (0.175) |
0.0349 (0.08) |
0.0185 (0.0497) |
0.247 (0.362) |
0.0116 (0.0351) |
| amp 2p25 1 | 150 (37%) | 258 |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.918 (0.934) |
0.856 (0.891) |
0.11 (0.195) |
8e-05 (0.000506) |
0.0564 (0.116) |
0.0259 (0.0625) |
0.0539 (0.112) |
8e-05 (0.000506) |
| amp 7p21 1 | 201 (49%) | 207 |
1e-05 (9.32e-05) |
0.00267 (0.0107) |
0.134 (0.229) |
0.317 (0.437) |
0.7 (0.766) |
0.0228 (0.0575) |
0.169 (0.271) |
0.00729 (0.025) |
0.401 (0.518) |
1e-05 (9.32e-05) |
| amp 11q22 2 | 71 (17%) | 337 |
3e-05 (0.00023) |
0.143 (0.238) |
0.732 (0.789) |
0.413 (0.529) |
0.43 (0.547) |
0.165 (0.267) |
0.0421 (0.0923) |
0.0229 (0.0575) |
0.00048 (0.00247) |
0.0199 (0.0529) |
| amp 19q13 43 | 154 (38%) | 254 |
1e-05 (9.32e-05) |
0.00073 (0.00357) |
0.18 (0.286) |
0.338 (0.458) |
0.209 (0.318) |
0.639 (0.711) |
0.502 (0.604) |
0.00314 (0.0125) |
0.0332 (0.0778) |
0.00481 (0.0178) |
| del 6p25 3 | 106 (26%) | 302 |
1e-05 (9.32e-05) |
0.00061 (0.00309) |
0.913 (0.932) |
0.947 (0.955) |
0.421 (0.538) |
0.0149 (0.0424) |
0.25 (0.365) |
0.0306 (0.0722) |
0.052 (0.109) |
0.00769 (0.0256) |
| del 6q21 | 190 (47%) | 218 |
1e-05 (9.32e-05) |
0.0194 (0.0518) |
0.887 (0.911) |
0.472 (0.585) |
0.546 (0.644) |
0.0892 (0.166) |
0.0158 (0.0445) |
0.00017 (0.000969) |
0.24 (0.357) |
3e-05 (0.00023) |
| del 8p23 3 | 242 (59%) | 166 |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.555 (0.645) |
0.194 (0.299) |
0.143 (0.238) |
0.00014 (0.000847) |
0.0974 (0.177) |
0.0135 (0.0395) |
0.133 (0.228) |
0.00178 (0.00744) |
| del 12p13 1 | 68 (17%) | 340 |
0.0107 (0.0332) |
0.00071 (0.0035) |
0.779 (0.83) |
0.663 (0.734) |
0.0063 (0.0222) |
4e-05 (0.000294) |
0.575 (0.662) |
0.619 (0.695) |
0.0167 (0.0467) |
0.212 (0.323) |
| del 17p12 | 209 (51%) | 199 |
1e-05 (9.32e-05) |
0.00112 (0.00505) |
0.2 (0.307) |
0.606 (0.688) |
0.0551 (0.114) |
0.00944 (0.0302) |
0.607 (0.688) |
0.00028 (0.00152) |
0.359 (0.477) |
8e-05 (0.000506) |
| del 18q23 | 180 (44%) | 228 |
3e-05 (0.00023) |
0.483 (0.594) |
0.691 (0.757) |
0.691 (0.757) |
0.462 (0.576) |
0.114 (0.201) |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.00601 (0.0214) |
0.00111 (0.00504) |
| del 19p13 3 | 146 (36%) | 262 |
1e-05 (9.32e-05) |
0.171 (0.273) |
0.901 (0.921) |
0.569 (0.659) |
0.0336 (0.078) |
0.00179 (0.00744) |
0.263 (0.378) |
0.00627 (0.0222) |
0.177 (0.281) |
0.00017 (0.000969) |
| amp 1q21 3 | 202 (50%) | 206 |
1e-05 (9.32e-05) |
0.00022 (0.00124) |
0.394 (0.511) |
0.723 (0.783) |
0.194 (0.299) |
0.115 (0.203) |
0.14 (0.236) |
0.0424 (0.0926) |
0.62 (0.696) |
0.00399 (0.0152) |
| amp 3q26 33 | 218 (53%) | 190 |
1e-05 (9.32e-05) |
0.687 (0.756) |
0.353 (0.473) |
0.0946 (0.175) |
0.534 (0.635) |
0.0228 (0.0575) |
0.54 (0.638) |
0.0059 (0.0213) |
0.182 (0.287) |
1e-05 (9.32e-05) |
| amp 4q13 3 | 62 (15%) | 346 |
1e-05 (9.32e-05) |
0.0114 (0.0347) |
0.581 (0.667) |
0.704 (0.769) |
0.102 (0.184) |
0.446 (0.562) |
0.00949 (0.0302) |
0.0678 (0.131) |
0.0669 (0.13) |
0.0414 (0.0923) |
| amp 7p11 2 | 190 (47%) | 218 |
1e-05 (9.32e-05) |
0.00878 (0.0284) |
0.0912 (0.169) |
0.597 (0.682) |
0.823 (0.864) |
0.257 (0.371) |
0.511 (0.611) |
0.0358 (0.0819) |
0.172 (0.275) |
3e-05 (0.00023) |
| amp 8p11 21 | 140 (34%) | 268 |
1e-05 (9.32e-05) |
0.0021 (0.00852) |
0.808 (0.854) |
0.985 (0.987) |
0.139 (0.235) |
0.31 (0.429) |
0.00768 (0.0256) |
0.0146 (0.0418) |
0.547 (0.644) |
0.247 (0.362) |
| amp 10p14 | 182 (45%) | 226 |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.356 (0.474) |
0.423 (0.54) |
0.35 (0.47) |
4e-05 (0.000294) |
0.105 (0.188) |
0.156 (0.254) |
0.456 (0.571) |
2e-05 (0.00017) |
| amp 19q12 | 164 (40%) | 244 |
1e-05 (9.32e-05) |
6e-05 (0.00041) |
0.798 (0.844) |
0.83 (0.869) |
0.305 (0.425) |
0.165 (0.267) |
0.275 (0.389) |
0.0127 (0.0377) |
0.24 (0.357) |
0.0281 (0.0669) |
| amp 22q12 2 | 87 (21%) | 321 |
1e-05 (9.32e-05) |
0.0183 (0.0496) |
0.414 (0.529) |
0.763 (0.816) |
0.00995 (0.0315) |
0.0635 (0.126) |
0.128 (0.223) |
0.256 (0.369) |
0.481 (0.592) |
0.048 (0.102) |
| del 4q34 2 | 177 (43%) | 231 |
1e-05 (9.32e-05) |
0.0178 (0.0486) |
0.486 (0.594) |
0.77 (0.822) |
0.214 (0.324) |
0.0418 (0.0923) |
0.291 (0.409) |
0.0628 (0.125) |
0.49 (0.597) |
0.00071 (0.0035) |
| del 16p13 3 | 174 (43%) | 234 |
1e-05 (9.32e-05) |
0.0014 (0.00615) |
0.226 (0.34) |
0.574 (0.662) |
0.862 (0.893) |
0.263 (0.378) |
0.614 (0.693) |
0.0374 (0.0844) |
0.553 (0.645) |
0.013 (0.0384) |
| del 16q23 1 | 119 (29%) | 289 |
1e-05 (9.32e-05) |
0.00232 (0.00936) |
0.501 (0.604) |
0.0643 (0.126) |
0.0527 (0.11) |
0.0634 (0.126) |
0.13 (0.226) |
0.0254 (0.0619) |
0.0847 (0.158) |
6e-05 (0.00041) |
| del xq21 33 | 84 (21%) | 324 |
0.241 (0.357) |
0.00683 (0.0236) |
0.98 (0.984) |
0.436 (0.553) |
0.0222 (0.057) |
0.0975 (0.177) |
0.087 (0.162) |
0.051 (0.107) |
0.0117 (0.0351) |
0.0185 (0.0497) |
| amp 6p22 3 | 170 (42%) | 238 |
1e-05 (9.32e-05) |
1e-05 (9.32e-05) |
0.327 (0.446) |
0.396 (0.513) |
0.268 (0.383) |
0.637 (0.71) |
0.081 (0.153) |
0.277 (0.391) |
0.231 (0.346) |
3e-05 (0.00023) |
| amp 8p11 23 | 123 (30%) | 285 |
1e-05 (9.32e-05) |
0.0113 (0.0343) |
0.818 (0.862) |
0.823 (0.864) |
0.491 (0.597) |
0.275 (0.389) |
0.0255 (0.0621) |
0.493 (0.598) |
0.56 (0.649) |
0.942 (0.953) |
| amp 12p12 1 | 131 (32%) | 277 |
0.00103 (0.00477) |
0.0576 (0.118) |
0.79 (0.838) |
0.55 (0.645) |
0.444 (0.561) |
0.548 (0.644) |
0.73 (0.789) |
0.029 (0.0688) |
0.0785 (0.148) |
0.0367 (0.0836) |
| amp 16p13 2 | 87 (21%) | 321 |
3e-05 (0.00023) |
7e-05 (0.00046) |
0.796 (0.843) |
0.899 (0.921) |
0.212 (0.323) |
0.0846 (0.158) |
0.182 (0.287) |
0.0706 (0.136) |
0.229 (0.344) |
0.0228 (0.0575) |
| amp 17q23 3 | 194 (48%) | 214 |
1e-05 (9.32e-05) |
0.0158 (0.0445) |
0.106 (0.19) |
0.138 (0.235) |
0.119 (0.208) |
0.364 (0.481) |
0.185 (0.29) |
0.469 (0.583) |
0.145 (0.241) |
0.00028 (0.00152) |
| del 1q32 1 | 71 (17%) | 337 |
0.00429 (0.0162) |
0.0175 (0.048) |
0.354 (0.473) |
0.605 (0.688) |
0.306 (0.426) |
0.0486 (0.103) |
0.553 (0.645) |
0.275 (0.389) |
0.403 (0.52) |
0.131 (0.226) |
| del 2q22 1 | 134 (33%) | 274 |
0.00074 (0.00357) |
0.0174 (0.048) |
0.271 (0.385) |
0.94 (0.953) |
0.145 (0.241) |
0.162 (0.263) |
0.0607 (0.122) |
0.25 (0.365) |
0.189 (0.294) |
0.00899 (0.029) |
| del 2q34 | 174 (43%) | 234 |
1e-05 (9.32e-05) |
0.00074 (0.00357) |
0.753 (0.807) |
0.582 (0.667) |
0.457 (0.571) |
0.108 (0.192) |
0.109 (0.193) |
0.534 (0.635) |
0.485 (0.594) |
0.00047 (0.00244) |
| del 7q36 3 | 60 (15%) | 348 |
0.00015 (0.000877) |
0.449 (0.566) |
0.0722 (0.138) |
0.223 (0.336) |
0.155 (0.254) |
0.484 (0.594) |
0.345 (0.465) |
0.00143 (0.00621) |
0.0622 (0.124) |
0.00373 (0.0143) |
| del 10q23 31 | 166 (41%) | 242 |
1e-05 (9.32e-05) |
0.00136 (0.00602) |
0.578 (0.665) |
0.473 (0.585) |
0.0455 (0.0978) |
0.628 (0.703) |
0.388 (0.505) |
0.0963 (0.176) |
0.608 (0.689) |
0.0644 (0.126) |
| amp 6q21 | 35 (9%) | 373 |
0.00494 (0.018) |
0.0474 (0.101) |
0.356 (0.474) |
0.108 (0.193) |
0.203 (0.311) |
0.0601 (0.122) |
0.852 (0.888) |
0.925 (0.94) |
0.246 (0.361) |
0.142 (0.238) |
| amp 11q13 3 | 135 (33%) | 273 |
1e-05 (9.32e-05) |
0.101 (0.182) |
0.236 (0.353) |
0.078 (0.148) |
0.0203 (0.0537) |
0.326 (0.444) |
0.374 (0.491) |
0.171 (0.273) |
0.328 (0.446) |
0.709 (0.772) |
| del 1p36 11 | 91 (22%) | 317 |
0.614 (0.693) |
0.0644 (0.126) |
0.167 (0.269) |
0.0242 (0.0602) |
0.599 (0.683) |
0.953 (0.96) |
0.708 (0.772) |
0.0479 (0.102) |
0.134 (0.229) |
0.253 (0.367) |
| amp 6q23 3 | 46 (11%) | 362 |
0.0136 (0.0395) |
0.715 (0.777) |
0.943 (0.953) |
0.0712 (0.137) |
0.268 (0.383) |
0.826 (0.866) |
0.14 (0.236) |
0.0985 (0.178) |
0.148 (0.244) |
0.128 (0.223) |
| amp 13q22 1 | 128 (31%) | 280 |
0.00046 (0.0024) |
0.858 (0.891) |
0.961 (0.967) |
0.849 (0.886) |
0.87 (0.9) |
0.371 (0.487) |
0.878 (0.905) |
0.556 (0.645) |
0.732 (0.789) |
0.225 (0.338) |
| del 10p11 21 | 74 (18%) | 334 |
0.362 (0.479) |
0.832 (0.87) |
0.537 (0.635) |
0.244 (0.359) |
0.00166 (0.00711) |
0.0667 (0.13) |
0.782 (0.832) |
0.0578 (0.118) |
0.375 (0.491) |
0.5 (0.604) |
| del 11q23 3 | 155 (38%) | 253 |
0.00182 (0.00752) |
0.0976 (0.177) |
0.723 (0.783) |
0.745 (0.8) |
0.0914 (0.169) |
0.361 (0.478) |
0.182 (0.287) |
0.143 (0.238) |
0.478 (0.589) |
0.473 (0.585) |
| del 11q25 | 143 (35%) | 265 |
7e-05 (0.00046) |
0.166 (0.268) |
0.86 (0.892) |
0.775 (0.827) |
0.0816 (0.153) |
0.311 (0.429) |
0.309 (0.429) |
0.184 (0.29) |
0.432 (0.55) |
0.267 (0.382) |
| del 12q24 33 | 88 (22%) | 320 |
3e-05 (0.00023) |
0.352 (0.472) |
0.917 (0.934) |
0.32 (0.438) |
0.816 (0.861) |
0.381 (0.497) |
1 (1.00) |
0.629 (0.703) |
0.982 (0.985) |
0.24 (0.357) |
| del xp11 3 | 92 (23%) | 316 |
0.191 (0.296) |
0.131 (0.226) |
0.738 (0.793) |
0.616 (0.693) |
0.132 (0.227) |
0.589 (0.674) |
0.106 (0.19) |
0.293 (0.41) |
0.52 (0.621) |
0.0338 (0.078) |
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S1. Gene #1: 'amp_1p34.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 1(1P34.2) MUTATED | 15 | 67 | 8 | 11 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 154 | 73 | 51 | 29 |
Figure S1. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0016
Table S2. Gene #1: 'amp_1p34.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 1(1P34.2) MUTATED | 29 | 46 | 10 | 16 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 109 | 70 | 59 | 69 |
Figure S2. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0349 (Fisher's exact test), Q value = 0.08
Table S3. Gene #1: 'amp_1p34.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 1(1P34.2) MUTATED | 32 | 32 | 37 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 88 | 64 | 152 |
Figure S3. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0185 (Fisher's exact test), Q value = 0.05
Table S4. Gene #1: 'amp_1p34.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 1(1P34.2) MUTATED | 22 | 30 | 12 | 19 | 18 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 67 | 69 | 81 | 51 | 36 |
Figure S4. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0116 (Fisher's exact test), Q value = 0.035
Table S5. Gene #1: 'amp_1p34.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 1(1P34.2) MUTATED | 19 | 17 | 26 | 19 | 1 | 18 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 55 | 29 | 67 | 47 | 30 | 66 |
Figure S5. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S6. Gene #2: 'amp_1q21.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 2(1Q21.3) MUTATED | 43 | 108 | 32 | 19 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 126 | 32 | 27 | 21 |
Figure S6. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0012
Table S7. Gene #2: 'amp_1q21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 2(1Q21.3) MUTATED | 58 | 77 | 27 | 40 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 80 | 39 | 42 | 45 |
Figure S7. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0424 (Fisher's exact test), Q value = 0.093
Table S8. Gene #2: 'amp_1q21.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 2(1Q21.3) MUTATED | 41 | 56 | 36 | 42 | 26 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 48 | 43 | 57 | 28 | 28 |
Figure S8. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00399 (Fisher's exact test), Q value = 0.015
Table S9. Gene #2: 'amp_1q21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 2(1Q21.3) MUTATED | 32 | 26 | 58 | 37 | 9 | 34 |
| AMP PEAK 2(1Q21.3) WILD-TYPE | 42 | 20 | 35 | 29 | 22 | 50 |
Figure S9. Get High-res Image Gene #2: 'amp_1q21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S10. Gene #3: 'amp_1q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 3(1Q23.3) MUTATED | 54 | 116 | 26 | 20 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 115 | 24 | 33 | 20 |
Figure S10. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0111 (Fisher's exact test), Q value = 0.034
Table S11. Gene #3: 'amp_1q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 3(1Q23.3) MUTATED | 68 | 76 | 30 | 42 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 70 | 40 | 39 | 43 |
Figure S11. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0259 (Fisher's exact test), Q value = 0.063
Table S12. Gene #3: 'amp_1q23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 3(1Q23.3) MUTATED | 75 | 53 | 87 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 43 | 59 | 87 |
Figure S12. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00175 (Fisher's exact test), Q value = 0.0074
Table S13. Gene #3: 'amp_1q23.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 3(1Q23.3) MUTATED | 58 | 66 | 91 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 62 | 30 | 98 |
Figure S13. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00307 (Fisher's exact test), Q value = 0.012
Table S14. Gene #3: 'amp_1q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 3(1Q23.3) MUTATED | 42 | 64 | 37 | 44 | 28 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 47 | 35 | 56 | 26 | 26 |
Figure S14. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0421 (Fisher's exact test), Q value = 0.092
Table S15. Gene #3: 'amp_1q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| AMP PEAK 3(1Q23.3) MUTATED | 46 | 31 | 68 | 65 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 52 | 12 | 66 | 54 |
Figure S15. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00142 (Fisher's exact test), Q value = 0.0062
Table S16. Gene #3: 'amp_1q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 3(1Q23.3) MUTATED | 36 | 33 | 58 | 37 | 10 | 36 |
| AMP PEAK 3(1Q23.3) WILD-TYPE | 38 | 13 | 35 | 29 | 21 | 48 |
Figure S16. Get High-res Image Gene #3: 'amp_1q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S17. Gene #4: 'amp_2p25.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 4(2P25.1) MUTATED | 28 | 86 | 14 | 22 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 141 | 54 | 45 | 18 |
Figure S17. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S18. Gene #4: 'amp_2p25.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 4(2P25.1) MUTATED | 38 | 73 | 15 | 24 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 100 | 43 | 54 | 61 |
Figure S18. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00051
Table S19. Gene #4: 'amp_2p25.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 4(2P25.1) MUTATED | 63 | 37 | 49 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 55 | 75 | 125 |
Figure S19. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0259 (Fisher's exact test), Q value = 0.063
Table S20. Gene #4: 'amp_2p25.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 4(2P25.1) MUTATED | 30 | 42 | 24 | 34 | 18 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 59 | 57 | 69 | 36 | 36 |
Figure S20. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00051
Table S21. Gene #4: 'amp_2p25.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 4(2P25.1) MUTATED | 26 | 24 | 46 | 25 | 3 | 22 |
| AMP PEAK 4(2P25.1) WILD-TYPE | 48 | 22 | 47 | 41 | 28 | 62 |
Figure S21. Get High-res Image Gene #4: 'amp_2p25.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S22. Gene #5: 'amp_3p25.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 5(3P25.2) MUTATED | 41 | 102 | 22 | 25 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 128 | 38 | 37 | 15 |
Figure S22. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S23. Gene #5: 'amp_3p25.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 5(3P25.2) MUTATED | 46 | 82 | 30 | 32 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 92 | 34 | 39 | 53 |
Figure S23. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0109 (Fisher's exact test), Q value = 0.033
Table S24. Gene #5: 'amp_3p25.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| AMP PEAK 5(3P25.2) MUTATED | 28 | 16 | 7 | 8 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 14 | 22 | 19 | 10 |
Figure S24. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S25. Gene #5: 'amp_3p25.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| AMP PEAK 5(3P25.2) MUTATED | 55 | 108 | 25 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 61 | 72 | 83 |
Figure S25. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S26. Gene #5: 'amp_3p25.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 5(3P25.2) MUTATED | 78 | 60 | 50 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 40 | 52 | 124 |
Figure S26. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.00088
Table S27. Gene #5: 'amp_3p25.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 5(3P25.2) MUTATED | 44 | 62 | 83 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 76 | 34 | 106 |
Figure S27. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S28. Gene #5: 'amp_3p25.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 5(3P25.2) MUTATED | 27 | 59 | 33 | 42 | 28 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 62 | 40 | 60 | 28 | 26 |
Figure S28. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S29. Gene #5: 'amp_3p25.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| AMP PEAK 5(3P25.2) MUTATED | 30 | 36 | 66 | 53 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 68 | 7 | 68 | 66 |
Figure S29. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S30. Gene #5: 'amp_3p25.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 5(3P25.2) MUTATED | 36 | 34 | 63 | 23 | 2 | 27 |
| AMP PEAK 5(3P25.2) WILD-TYPE | 38 | 12 | 30 | 43 | 29 | 57 |
Figure S30. Get High-res Image Gene #5: 'amp_3p25.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S31. Gene #6: 'amp_3q26.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 6(3Q26.33) MUTATED | 62 | 100 | 28 | 28 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 107 | 40 | 31 | 12 |
Figure S31. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0228 (Fisher's exact test), Q value = 0.057
Table S32. Gene #6: 'amp_3q26.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 6(3Q26.33) MUTATED | 74 | 50 | 93 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 44 | 62 | 81 |
Figure S32. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0059 (Fisher's exact test), Q value = 0.021
Table S33. Gene #6: 'amp_3q26.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 6(3Q26.33) MUTATED | 50 | 56 | 34 | 44 | 32 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 39 | 43 | 59 | 26 | 22 |
Figure S33. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S34. Gene #6: 'amp_3q26.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 6(3Q26.33) MUTATED | 36 | 30 | 58 | 42 | 4 | 40 |
| AMP PEAK 6(3Q26.33) WILD-TYPE | 38 | 16 | 35 | 24 | 27 | 44 |
Figure S34. Get High-res Image Gene #6: 'amp_3q26.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0462 (Fisher's exact test), Q value = 0.099
Table S35. Gene #7: 'amp_4p16.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 7(4P16.3) MUTATED | 23 | 34 | 7 | 9 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 146 | 106 | 52 | 31 |
Figure S35. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.021 (Fisher's exact test), Q value = 0.055
Table S36. Gene #7: 'amp_4p16.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 7(4P16.3) MUTATED | 15 | 29 | 11 | 18 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 123 | 87 | 58 | 67 |
Figure S36. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0499 (Fisher's exact test), Q value = 0.1
Table S37. Gene #7: 'amp_4p16.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| AMP PEAK 7(4P16.3) MUTATED | 13 | 3 | 6 | 2 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 29 | 35 | 20 | 16 |
Figure S37. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00033 (Fisher's exact test), Q value = 0.0018
Table S38. Gene #7: 'amp_4p16.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| AMP PEAK 7(4P16.3) MUTATED | 10 | 47 | 15 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 106 | 133 | 93 |
Figure S38. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.00088
Table S39. Gene #7: 'amp_4p16.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 7(4P16.3) MUTATED | 20 | 34 | 18 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 98 | 78 | 156 |
Figure S39. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S40. Gene #7: 'amp_4p16.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 7(4P16.3) MUTATED | 6 | 27 | 40 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 114 | 69 | 149 |
Figure S40. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0338 (Fisher's exact test), Q value = 0.078
Table S41. Gene #7: 'amp_4p16.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 7(4P16.3) MUTATED | 13 | 22 | 18 | 17 | 3 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 76 | 77 | 75 | 53 | 51 |
Figure S41. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0262 (Fisher's exact test), Q value = 0.063
Table S42. Gene #7: 'amp_4p16.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 7(4P16.3) MUTATED | 5 | 9 | 22 | 15 | 8 | 12 |
| AMP PEAK 7(4P16.3) WILD-TYPE | 69 | 37 | 71 | 51 | 23 | 72 |
Figure S42. Get High-res Image Gene #7: 'amp_4p16.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S43. Gene #8: 'amp_4q13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 8(4Q13.3) MUTATED | 11 | 40 | 4 | 7 |
| AMP PEAK 8(4Q13.3) WILD-TYPE | 158 | 100 | 55 | 33 |
Figure S43. Get High-res Image Gene #8: 'amp_4q13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0114 (Fisher's exact test), Q value = 0.035
Table S44. Gene #8: 'amp_4q13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 8(4Q13.3) MUTATED | 17 | 28 | 5 | 12 |
| AMP PEAK 8(4Q13.3) WILD-TYPE | 121 | 88 | 64 | 73 |
Figure S44. Get High-res Image Gene #8: 'amp_4q13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00949 (Fisher's exact test), Q value = 0.03
Table S45. Gene #8: 'amp_4q13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 8(4Q13.3) MUTATED | 9 | 20 | 33 |
| AMP PEAK 8(4Q13.3) WILD-TYPE | 111 | 76 | 156 |
Figure S45. Get High-res Image Gene #8: 'amp_4q13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0414 (Fisher's exact test), Q value = 0.092
Table S46. Gene #8: 'amp_4q13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 8(4Q13.3) MUTATED | 6 | 7 | 22 | 14 | 3 | 9 |
| AMP PEAK 8(4Q13.3) WILD-TYPE | 68 | 39 | 71 | 52 | 28 | 75 |
Figure S46. Get High-res Image Gene #8: 'amp_4q13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S47. Gene #9: 'amp_5p15.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 9(5P15.33) MUTATED | 42 | 96 | 42 | 25 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 127 | 44 | 17 | 15 |
Figure S47. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00732 (Fisher's exact test), Q value = 0.025
Table S48. Gene #9: 'amp_5p15.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 9(5P15.33) MUTATED | 75 | 65 | 22 | 43 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 63 | 51 | 47 | 42 |
Figure S48. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0236 (Fisher's exact test), Q value = 0.059
Table S49. Gene #9: 'amp_5p15.33' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 37 | 29 | 34 | 5 | 19 |
| AMP PEAK 9(5P15.33) MUTATED | 17 | 8 | 18 | 0 | 12 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 20 | 21 | 16 | 5 | 7 |
Figure S49. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0178 (Fisher's exact test), Q value = 0.049
Table S50. Gene #9: 'amp_5p15.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 9(5P15.33) MUTATED | 50 | 51 | 101 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 68 | 61 | 73 |
Figure S50. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S51. Gene #9: 'amp_5p15.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 9(5P15.33) MUTATED | 43 | 62 | 27 | 41 | 31 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 46 | 37 | 66 | 29 | 23 |
Figure S51. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0011 (Fisher's exact test), Q value = 0.005
Table S52. Gene #9: 'amp_5p15.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 9(5P15.33) MUTATED | 31 | 26 | 50 | 37 | 6 | 51 |
| AMP PEAK 9(5P15.33) WILD-TYPE | 43 | 20 | 43 | 29 | 25 | 33 |
Figure S52. Get High-res Image Gene #9: 'amp_5p15.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S53. Gene #10: 'amp_6p22.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 10(6P22.3) MUTATED | 25 | 94 | 36 | 15 |
| AMP PEAK 10(6P22.3) WILD-TYPE | 144 | 46 | 23 | 25 |
Figure S53. Get High-res Image Gene #10: 'amp_6p22.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S54. Gene #10: 'amp_6p22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 10(6P22.3) MUTATED | 53 | 73 | 20 | 24 |
| AMP PEAK 10(6P22.3) WILD-TYPE | 85 | 43 | 49 | 61 |
Figure S54. Get High-res Image Gene #10: 'amp_6p22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S55. Gene #10: 'amp_6p22.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 10(6P22.3) MUTATED | 28 | 18 | 58 | 20 | 4 | 40 |
| AMP PEAK 10(6P22.3) WILD-TYPE | 46 | 28 | 35 | 46 | 27 | 44 |
Figure S55. Get High-res Image Gene #10: 'amp_6p22.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00494 (Fisher's exact test), Q value = 0.018
Table S56. Gene #11: 'amp_6q21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 11(6Q21) MUTATED | 9 | 20 | 6 | 0 |
| AMP PEAK 11(6Q21) WILD-TYPE | 160 | 120 | 53 | 40 |
Figure S56. Get High-res Image Gene #11: 'amp_6q21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0474 (Fisher's exact test), Q value = 0.1
Table S57. Gene #11: 'amp_6q21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 11(6Q21) MUTATED | 7 | 17 | 6 | 5 |
| AMP PEAK 11(6Q21) WILD-TYPE | 131 | 99 | 63 | 80 |
Figure S57. Get High-res Image Gene #11: 'amp_6q21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0136 (Fisher's exact test), Q value = 0.04
Table S58. Gene #12: 'amp_6q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 12(6Q23.3) MUTATED | 12 | 26 | 5 | 3 |
| AMP PEAK 12(6Q23.3) WILD-TYPE | 157 | 114 | 54 | 37 |
Figure S58. Get High-res Image Gene #12: 'amp_6q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S59. Gene #13: 'amp_7p21.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 13(7P21.1) MUTATED | 40 | 95 | 38 | 28 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 129 | 45 | 21 | 12 |
Figure S59. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00267 (Fisher's exact test), Q value = 0.011
Table S60. Gene #13: 'amp_7p21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 13(7P21.1) MUTATED | 69 | 72 | 26 | 34 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 69 | 44 | 43 | 51 |
Figure S60. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0228 (Fisher's exact test), Q value = 0.057
Table S61. Gene #13: 'amp_7p21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 13(7P21.1) MUTATED | 65 | 43 | 91 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 53 | 69 | 83 |
Figure S61. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00729 (Fisher's exact test), Q value = 0.025
Table S62. Gene #13: 'amp_7p21.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 13(7P21.1) MUTATED | 47 | 53 | 32 | 43 | 24 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 42 | 46 | 61 | 27 | 30 |
Figure S62. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S63. Gene #13: 'amp_7p21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 13(7P21.1) MUTATED | 29 | 21 | 55 | 38 | 2 | 49 |
| AMP PEAK 13(7P21.1) WILD-TYPE | 45 | 25 | 38 | 28 | 29 | 35 |
Figure S63. Get High-res Image Gene #13: 'amp_7p21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S64. Gene #14: 'amp_7p11.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 14(7P11.2) MUTATED | 37 | 88 | 38 | 27 |
| AMP PEAK 14(7P11.2) WILD-TYPE | 132 | 52 | 21 | 13 |
Figure S64. Get High-res Image Gene #14: 'amp_7p11.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00878 (Fisher's exact test), Q value = 0.028
Table S65. Gene #14: 'amp_7p11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 14(7P11.2) MUTATED | 66 | 67 | 24 | 33 |
| AMP PEAK 14(7P11.2) WILD-TYPE | 72 | 49 | 45 | 52 |
Figure S65. Get High-res Image Gene #14: 'amp_7p11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0358 (Fisher's exact test), Q value = 0.082
Table S66. Gene #14: 'amp_7p11.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 14(7P11.2) MUTATED | 48 | 49 | 32 | 38 | 22 |
| AMP PEAK 14(7P11.2) WILD-TYPE | 41 | 50 | 61 | 32 | 32 |
Figure S66. Get High-res Image Gene #14: 'amp_7p11.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S67. Gene #14: 'amp_7p11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 14(7P11.2) MUTATED | 27 | 21 | 51 | 35 | 3 | 47 |
| AMP PEAK 14(7P11.2) WILD-TYPE | 47 | 25 | 42 | 31 | 28 | 37 |
Figure S67. Get High-res Image Gene #14: 'amp_7p11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S68. Gene #15: 'amp_8p11.23' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 15(8P11.23) MUTATED | 36 | 36 | 17 | 34 |
| AMP PEAK 15(8P11.23) WILD-TYPE | 133 | 104 | 42 | 6 |
Figure S68. Get High-res Image Gene #15: 'amp_8p11.23' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.034
Table S69. Gene #15: 'amp_8p11.23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 15(8P11.23) MUTATED | 35 | 41 | 13 | 34 |
| AMP PEAK 15(8P11.23) WILD-TYPE | 103 | 75 | 56 | 51 |
Figure S69. Get High-res Image Gene #15: 'amp_8p11.23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0255 (Fisher's exact test), Q value = 0.062
Table S70. Gene #15: 'amp_8p11.23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 15(8P11.23) MUTATED | 27 | 26 | 69 |
| AMP PEAK 15(8P11.23) WILD-TYPE | 93 | 70 | 120 |
Figure S70. Get High-res Image Gene #15: 'amp_8p11.23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S71. Gene #16: 'amp_8p11.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 16(8P11.21) MUTATED | 40 | 46 | 18 | 36 |
| AMP PEAK 16(8P11.21) WILD-TYPE | 129 | 94 | 41 | 4 |
Figure S71. Get High-res Image Gene #16: 'amp_8p11.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0021 (Fisher's exact test), Q value = 0.0085
Table S72. Gene #16: 'amp_8p11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 16(8P11.21) MUTATED | 40 | 52 | 14 | 34 |
| AMP PEAK 16(8P11.21) WILD-TYPE | 98 | 64 | 55 | 51 |
Figure S72. Get High-res Image Gene #16: 'amp_8p11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00768 (Fisher's exact test), Q value = 0.026
Table S73. Gene #16: 'amp_8p11.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 16(8P11.21) MUTATED | 30 | 30 | 79 |
| AMP PEAK 16(8P11.21) WILD-TYPE | 90 | 66 | 110 |
Figure S73. Get High-res Image Gene #16: 'amp_8p11.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0146 (Fisher's exact test), Q value = 0.042
Table S74. Gene #16: 'amp_8p11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 16(8P11.21) MUTATED | 29 | 34 | 30 | 35 | 11 |
| AMP PEAK 16(8P11.21) WILD-TYPE | 60 | 65 | 63 | 35 | 43 |
Figure S74. Get High-res Image Gene #16: 'amp_8p11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S75. Gene #17: 'amp_8q22.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 17(8Q22.3) MUTATED | 82 | 110 | 36 | 36 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 87 | 30 | 23 | 4 |
Figure S75. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S76. Gene #17: 'amp_8q22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 17(8Q22.3) MUTATED | 83 | 96 | 34 | 51 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 55 | 20 | 35 | 34 |
Figure S76. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0249 (Fisher's exact test), Q value = 0.061
Table S77. Gene #17: 'amp_8q22.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 37 | 29 | 34 | 5 | 19 |
| AMP PEAK 17(8Q22.3) MUTATED | 22 | 11 | 26 | 4 | 13 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 15 | 18 | 8 | 1 | 6 |
Figure S77. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0184 (Fisher's exact test), Q value = 0.05
Table S78. Gene #17: 'amp_8q22.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 17(8Q22.3) MUTATED | 66 | 70 | 126 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 54 | 26 | 63 |
Figure S78. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00594 (Fisher's exact test), Q value = 0.021
Table S79. Gene #17: 'amp_8q22.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 17(8Q22.3) MUTATED | 57 | 70 | 51 | 55 | 29 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 32 | 29 | 42 | 15 | 25 |
Figure S79. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.00088
Table S80. Gene #17: 'amp_8q22.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 17(8Q22.3) MUTATED | 42 | 36 | 71 | 43 | 10 | 55 |
| AMP PEAK 17(8Q22.3) WILD-TYPE | 32 | 10 | 22 | 23 | 21 | 29 |
Figure S80. Get High-res Image Gene #17: 'amp_8q22.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S81. Gene #18: 'amp_9p24.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 18(9P24.1) MUTATED | 18 | 31 | 31 | 8 |
| AMP PEAK 18(9P24.1) WILD-TYPE | 151 | 109 | 28 | 32 |
Figure S81. Get High-res Image Gene #18: 'amp_9p24.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0033
Table S82. Gene #18: 'amp_9p24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 18(9P24.1) MUTATED | 44 | 20 | 6 | 18 |
| AMP PEAK 18(9P24.1) WILD-TYPE | 94 | 96 | 63 | 67 |
Figure S82. Get High-res Image Gene #18: 'amp_9p24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0265 (Fisher's exact test), Q value = 0.064
Table S83. Gene #18: 'amp_9p24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| AMP PEAK 18(9P24.1) MUTATED | 25 | 29 | 32 |
| AMP PEAK 18(9P24.1) WILD-TYPE | 91 | 151 | 76 |
Figure S83. Get High-res Image Gene #18: 'amp_9p24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00184 (Fisher's exact test), Q value = 0.0076
Table S84. Gene #18: 'amp_9p24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 18(9P24.1) MUTATED | 21 | 14 | 51 |
| AMP PEAK 18(9P24.1) WILD-TYPE | 97 | 98 | 123 |
Figure S84. Get High-res Image Gene #18: 'amp_9p24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0435 (Fisher's exact test), Q value = 0.094
Table S85. Gene #18: 'amp_9p24.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 18(9P24.1) MUTATED | 27 | 23 | 11 | 15 | 12 |
| AMP PEAK 18(9P24.1) WILD-TYPE | 62 | 76 | 82 | 55 | 42 |
Figure S85. Get High-res Image Gene #18: 'amp_9p24.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00046
Table S86. Gene #18: 'amp_9p24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| AMP PEAK 18(9P24.1) MUTATED | 38 | 7 | 18 | 22 |
| AMP PEAK 18(9P24.1) WILD-TYPE | 60 | 36 | 116 | 97 |
Figure S86. Get High-res Image Gene #18: 'amp_9p24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00067
Table S87. Gene #18: 'amp_9p24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 18(9P24.1) MUTATED | 18 | 8 | 19 | 6 | 2 | 32 |
| AMP PEAK 18(9P24.1) WILD-TYPE | 56 | 38 | 74 | 60 | 29 | 52 |
Figure S87. Get High-res Image Gene #18: 'amp_9p24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S88. Gene #19: 'amp_10p14' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 19(10P14) MUTATED | 25 | 99 | 33 | 25 |
| AMP PEAK 19(10P14) WILD-TYPE | 144 | 41 | 26 | 15 |
Figure S88. Get High-res Image Gene #19: 'amp_10p14' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S89. Gene #19: 'amp_10p14' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 19(10P14) MUTATED | 54 | 76 | 27 | 25 |
| AMP PEAK 19(10P14) WILD-TYPE | 84 | 40 | 42 | 60 |
Figure S89. Get High-res Image Gene #19: 'amp_10p14' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S90. Gene #19: 'amp_10p14' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 19(10P14) MUTATED | 73 | 39 | 68 |
| AMP PEAK 19(10P14) WILD-TYPE | 45 | 73 | 106 |
Figure S90. Get High-res Image Gene #19: 'amp_10p14' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S91. Gene #19: 'amp_10p14' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 19(10P14) MUTATED | 35 | 24 | 52 | 32 | 2 | 31 |
| AMP PEAK 19(10P14) WILD-TYPE | 39 | 22 | 41 | 34 | 29 | 53 |
Figure S91. Get High-res Image Gene #19: 'amp_10p14' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S92. Gene #20: 'amp_11p13' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 20(11P13) MUTATED | 7 | 15 | 24 | 5 |
| AMP PEAK 20(11P13) WILD-TYPE | 162 | 125 | 35 | 35 |
Figure S92. Get High-res Image Gene #20: 'amp_11p13' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00489 (Fisher's exact test), Q value = 0.018
Table S93. Gene #20: 'amp_11p13' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 20(11P13) MUTATED | 24 | 19 | 3 | 5 |
| AMP PEAK 20(11P13) WILD-TYPE | 114 | 97 | 66 | 80 |
Figure S93. Get High-res Image Gene #20: 'amp_11p13' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0334 (Fisher's exact test), Q value = 0.078
Table S94. Gene #20: 'amp_11p13' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 37 | 29 | 34 | 5 | 19 |
| AMP PEAK 20(11P13) MUTATED | 1 | 2 | 7 | 0 | 5 |
| AMP PEAK 20(11P13) WILD-TYPE | 36 | 27 | 27 | 5 | 14 |
Figure S94. Get High-res Image Gene #20: 'amp_11p13' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00374 (Fisher's exact test), Q value = 0.014
Table S95. Gene #20: 'amp_11p13' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| AMP PEAK 20(11P13) MUTATED | 1 | 3 | 5 | 6 |
| AMP PEAK 20(11P13) WILD-TYPE | 41 | 35 | 21 | 12 |
Figure S95. Get High-res Image Gene #20: 'amp_11p13' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00064 (Fisher's exact test), Q value = 0.0032
Table S96. Gene #20: 'amp_11p13' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 20(11P13) MUTATED | 16 | 4 | 31 |
| AMP PEAK 20(11P13) WILD-TYPE | 102 | 108 | 143 |
Figure S96. Get High-res Image Gene #20: 'amp_11p13' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00327 (Fisher's exact test), Q value = 0.013
Table S97. Gene #20: 'amp_11p13' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 20(11P13) MUTATED | 9 | 3 | 9 | 9 | 0 | 21 |
| AMP PEAK 20(11P13) WILD-TYPE | 65 | 43 | 84 | 57 | 31 | 63 |
Figure S97. Get High-res Image Gene #20: 'amp_11p13' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S98. Gene #21: 'amp_11q13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 21(11Q13.3) MUTATED | 41 | 55 | 14 | 25 |
| AMP PEAK 21(11Q13.3) WILD-TYPE | 128 | 85 | 45 | 15 |
Figure S98. Get High-res Image Gene #21: 'amp_11q13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0203 (Fisher's exact test), Q value = 0.054
Table S99. Gene #21: 'amp_11q13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| AMP PEAK 21(11Q13.3) MUTATED | 27 | 69 | 38 |
| AMP PEAK 21(11Q13.3) WILD-TYPE | 89 | 111 | 70 |
Figure S99. Get High-res Image Gene #21: 'amp_11q13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S100. Gene #22: 'amp_11q22.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 22(11Q22.2) MUTATED | 14 | 28 | 13 | 16 |
| AMP PEAK 22(11Q22.2) WILD-TYPE | 155 | 112 | 46 | 24 |
Figure S100. Get High-res Image Gene #22: 'amp_11q22.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0421 (Fisher's exact test), Q value = 0.092
Table S101. Gene #22: 'amp_11q22.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 22(11Q22.2) MUTATED | 16 | 25 | 30 |
| AMP PEAK 22(11Q22.2) WILD-TYPE | 104 | 71 | 159 |
Figure S101. Get High-res Image Gene #22: 'amp_11q22.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0229 (Fisher's exact test), Q value = 0.057
Table S102. Gene #22: 'amp_11q22.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 22(11Q22.2) MUTATED | 15 | 26 | 10 | 15 | 5 |
| AMP PEAK 22(11Q22.2) WILD-TYPE | 74 | 73 | 83 | 55 | 49 |
Figure S102. Get High-res Image Gene #22: 'amp_11q22.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00048 (Fisher's exact test), Q value = 0.0025
Table S103. Gene #22: 'amp_11q22.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| AMP PEAK 22(11Q22.2) MUTATED | 29 | 12 | 15 | 15 |
| AMP PEAK 22(11Q22.2) WILD-TYPE | 69 | 31 | 119 | 104 |
Figure S103. Get High-res Image Gene #22: 'amp_11q22.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0199 (Fisher's exact test), Q value = 0.053
Table S104. Gene #22: 'amp_11q22.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 22(11Q22.2) MUTATED | 10 | 13 | 12 | 11 | 2 | 23 |
| AMP PEAK 22(11Q22.2) WILD-TYPE | 64 | 33 | 81 | 55 | 29 | 61 |
Figure S104. Get High-res Image Gene #22: 'amp_11q22.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00103 (Fisher's exact test), Q value = 0.0048
Table S105. Gene #23: 'amp_12p12.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 23(12P12.1) MUTATED | 36 | 54 | 24 | 17 |
| AMP PEAK 23(12P12.1) WILD-TYPE | 133 | 86 | 35 | 23 |
Figure S105. Get High-res Image Gene #23: 'amp_12p12.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.029 (Fisher's exact test), Q value = 0.069
Table S106. Gene #23: 'amp_12p12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 23(12P12.1) MUTATED | 34 | 33 | 21 | 30 | 13 |
| AMP PEAK 23(12P12.1) WILD-TYPE | 55 | 66 | 72 | 40 | 41 |
Figure S106. Get High-res Image Gene #23: 'amp_12p12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0367 (Fisher's exact test), Q value = 0.084
Table S107. Gene #23: 'amp_12p12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 23(12P12.1) MUTATED | 15 | 14 | 34 | 27 | 6 | 32 |
| AMP PEAK 23(12P12.1) WILD-TYPE | 59 | 32 | 59 | 39 | 25 | 52 |
Figure S107. Get High-res Image Gene #23: 'amp_12p12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00103 (Fisher's exact test), Q value = 0.0048
Table S108. Gene #24: 'amp_12q15' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 24(12Q15) MUTATED | 42 | 57 | 9 | 10 |
| AMP PEAK 24(12Q15) WILD-TYPE | 127 | 83 | 50 | 30 |
Figure S108. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0381 (Fisher's exact test), Q value = 0.086
Table S109. Gene #24: 'amp_12q15' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 37 | 29 | 34 | 5 | 19 |
| AMP PEAK 24(12Q15) MUTATED | 18 | 4 | 12 | 2 | 5 |
| AMP PEAK 24(12Q15) WILD-TYPE | 19 | 25 | 22 | 3 | 14 |
Figure S109. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0199 (Fisher's exact test), Q value = 0.053
Table S110. Gene #24: 'amp_12q15' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| AMP PEAK 24(12Q15) MUTATED | 20 | 6 | 8 | 7 |
| AMP PEAK 24(12Q15) WILD-TYPE | 22 | 32 | 18 | 11 |
Figure S110. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0043 (Fisher's exact test), Q value = 0.016
Table S111. Gene #24: 'amp_12q15' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| AMP PEAK 24(12Q15) MUTATED | 35 | 64 | 19 |
| AMP PEAK 24(12Q15) WILD-TYPE | 81 | 116 | 89 |
Figure S111. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00856 (Fisher's exact test), Q value = 0.028
Table S112. Gene #24: 'amp_12q15' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 24(12Q15) MUTATED | 41 | 40 | 37 |
| AMP PEAK 24(12Q15) WILD-TYPE | 77 | 72 | 137 |
Figure S112. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0205 (Fisher's exact test), Q value = 0.054
Table S113. Gene #24: 'amp_12q15' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 24(12Q15) MUTATED | 16 | 35 | 23 | 27 | 17 |
| AMP PEAK 24(12Q15) WILD-TYPE | 73 | 64 | 70 | 43 | 37 |
Figure S113. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00751 (Fisher's exact test), Q value = 0.026
Table S114. Gene #24: 'amp_12q15' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| AMP PEAK 24(12Q15) MUTATED | 17 | 18 | 41 | 41 |
| AMP PEAK 24(12Q15) WILD-TYPE | 81 | 25 | 93 | 78 |
Figure S114. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 5e-04 (Fisher's exact test), Q value = 0.0026
Table S115. Gene #24: 'amp_12q15' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 24(12Q15) MUTATED | 21 | 17 | 31 | 30 | 7 | 11 |
| AMP PEAK 24(12Q15) WILD-TYPE | 53 | 29 | 62 | 36 | 24 | 73 |
Figure S115. Get High-res Image Gene #24: 'amp_12q15' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0024
Table S116. Gene #25: 'amp_13q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 25(13Q22.1) MUTATED | 34 | 56 | 23 | 15 |
| AMP PEAK 25(13Q22.1) WILD-TYPE | 135 | 84 | 36 | 25 |
Figure S116. Get High-res Image Gene #25: 'amp_13q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S117. Gene #26: 'amp_16p13.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 26(16P13.2) MUTATED | 22 | 50 | 9 | 6 |
| AMP PEAK 26(16P13.2) WILD-TYPE | 147 | 90 | 50 | 34 |
Figure S117. Get High-res Image Gene #26: 'amp_16p13.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00046
Table S118. Gene #26: 'amp_16p13.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 26(16P13.2) MUTATED | 26 | 42 | 10 | 9 |
| AMP PEAK 26(16P13.2) WILD-TYPE | 112 | 74 | 59 | 76 |
Figure S118. Get High-res Image Gene #26: 'amp_16p13.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0228 (Fisher's exact test), Q value = 0.057
Table S119. Gene #26: 'amp_16p13.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 26(16P13.2) MUTATED | 14 | 12 | 29 | 13 | 1 | 18 |
| AMP PEAK 26(16P13.2) WILD-TYPE | 60 | 34 | 64 | 53 | 30 | 66 |
Figure S119. Get High-res Image Gene #26: 'amp_16p13.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S120. Gene #27: 'amp_16q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 27(16Q22.1) MUTATED | 31 | 58 | 10 | 9 |
| AMP PEAK 27(16Q22.1) WILD-TYPE | 138 | 82 | 49 | 31 |
Figure S120. Get High-res Image Gene #27: 'amp_16q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0425 (Fisher's exact test), Q value = 0.093
Table S121. Gene #27: 'amp_16q22.1' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 37 | 29 | 34 | 5 | 19 |
| AMP PEAK 27(16Q22.1) MUTATED | 7 | 6 | 16 | 0 | 6 |
| AMP PEAK 27(16Q22.1) WILD-TYPE | 30 | 23 | 18 | 5 | 13 |
Figure S121. Get High-res Image Gene #27: 'amp_16q22.1' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.023 (Fisher's exact test), Q value = 0.058
Table S122. Gene #27: 'amp_16q22.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| AMP PEAK 27(16Q22.1) MUTATED | 6 | 10 | 12 | 7 |
| AMP PEAK 27(16Q22.1) WILD-TYPE | 36 | 28 | 14 | 11 |
Figure S122. Get High-res Image Gene #27: 'amp_16q22.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00461 (Fisher's exact test), Q value = 0.017
Table S123. Gene #27: 'amp_16q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 27(16Q22.1) MUTATED | 41 | 18 | 48 |
| AMP PEAK 27(16Q22.1) WILD-TYPE | 77 | 94 | 126 |
Figure S123. Get High-res Image Gene #27: 'amp_16q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.042 (Fisher's exact test), Q value = 0.092
Table S124. Gene #27: 'amp_16q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 27(16Q22.1) MUTATED | 35 | 33 | 40 |
| AMP PEAK 27(16Q22.1) WILD-TYPE | 85 | 63 | 149 |
Figure S124. Get High-res Image Gene #27: 'amp_16q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00864 (Fisher's exact test), Q value = 0.028
Table S125. Gene #27: 'amp_16q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 27(16Q22.1) MUTATED | 25 | 35 | 13 | 17 | 18 |
| AMP PEAK 27(16Q22.1) WILD-TYPE | 64 | 64 | 80 | 53 | 36 |
Figure S125. Get High-res Image Gene #27: 'amp_16q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0065 (Fisher's exact test), Q value = 0.023
Table S126. Gene #27: 'amp_16q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 27(16Q22.1) MUTATED | 23 | 13 | 23 | 25 | 1 | 22 |
| AMP PEAK 27(16Q22.1) WILD-TYPE | 51 | 33 | 70 | 41 | 30 | 62 |
Figure S126. Get High-res Image Gene #27: 'amp_16q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S127. Gene #28: 'amp_17q12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 28(17Q12) MUTATED | 46 | 77 | 18 | 25 |
| AMP PEAK 28(17Q12) WILD-TYPE | 123 | 63 | 41 | 15 |
Figure S127. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0013 (Fisher's exact test), Q value = 0.0058
Table S128. Gene #28: 'amp_17q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 28(17Q12) MUTATED | 40 | 61 | 27 | 38 |
| AMP PEAK 28(17Q12) WILD-TYPE | 98 | 55 | 42 | 47 |
Figure S128. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0205 (Fisher's exact test), Q value = 0.054
Table S129. Gene #28: 'amp_17q12' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| AMP PEAK 28(17Q12) MUTATED | 26 | 11 | 9 | 8 |
| AMP PEAK 28(17Q12) WILD-TYPE | 16 | 27 | 17 | 10 |
Figure S129. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0017 (Fisher's exact test), Q value = 0.0072
Table S130. Gene #28: 'amp_17q12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| AMP PEAK 28(17Q12) MUTATED | 40 | 91 | 34 |
| AMP PEAK 28(17Q12) WILD-TYPE | 76 | 89 | 74 |
Figure S130. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0248 (Fisher's exact test), Q value = 0.061
Table S131. Gene #28: 'amp_17q12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 28(17Q12) MUTATED | 50 | 56 | 59 |
| AMP PEAK 28(17Q12) WILD-TYPE | 68 | 56 | 115 |
Figure S131. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00365 (Fisher's exact test), Q value = 0.014
Table S132. Gene #28: 'amp_17q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| AMP PEAK 28(17Q12) MUTATED | 35 | 49 | 81 |
| AMP PEAK 28(17Q12) WILD-TYPE | 85 | 47 | 108 |
Figure S132. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0293 (Fisher's exact test), Q value = 0.069
Table S133. Gene #28: 'amp_17q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 28(17Q12) MUTATED | 29 | 46 | 33 | 38 | 19 |
| AMP PEAK 28(17Q12) WILD-TYPE | 60 | 53 | 60 | 32 | 35 |
Figure S133. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0105 (Fisher's exact test), Q value = 0.033
Table S134. Gene #28: 'amp_17q12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| AMP PEAK 28(17Q12) MUTATED | 31 | 24 | 64 | 43 |
| AMP PEAK 28(17Q12) WILD-TYPE | 67 | 19 | 70 | 76 |
Figure S134. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S135. Gene #28: 'amp_17q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 28(17Q12) MUTATED | 23 | 26 | 57 | 25 | 5 | 26 |
| AMP PEAK 28(17Q12) WILD-TYPE | 51 | 20 | 36 | 41 | 26 | 58 |
Figure S135. Get High-res Image Gene #28: 'amp_17q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S136. Gene #29: 'amp_17q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 29(17Q23.3) MUTATED | 56 | 87 | 24 | 27 |
| AMP PEAK 29(17Q23.3) WILD-TYPE | 113 | 53 | 35 | 13 |
Figure S136. Get High-res Image Gene #29: 'amp_17q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0158 (Fisher's exact test), Q value = 0.045
Table S137. Gene #29: 'amp_17q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 29(17Q23.3) MUTATED | 55 | 69 | 30 | 40 |
| AMP PEAK 29(17Q23.3) WILD-TYPE | 83 | 47 | 39 | 45 |
Figure S137. Get High-res Image Gene #29: 'amp_17q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00028 (Fisher's exact test), Q value = 0.0015
Table S138. Gene #29: 'amp_17q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 29(17Q23.3) MUTATED | 28 | 27 | 55 | 38 | 6 | 36 |
| AMP PEAK 29(17Q23.3) WILD-TYPE | 46 | 19 | 38 | 28 | 25 | 48 |
Figure S138. Get High-res Image Gene #29: 'amp_17q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S139. Gene #30: 'amp_19q12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 30(19Q12) MUTATED | 35 | 91 | 21 | 17 |
| AMP PEAK 30(19Q12) WILD-TYPE | 134 | 49 | 38 | 23 |
Figure S139. Get High-res Image Gene #30: 'amp_19q12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00041
Table S140. Gene #30: 'amp_19q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 30(19Q12) MUTATED | 43 | 67 | 27 | 27 |
| AMP PEAK 30(19Q12) WILD-TYPE | 95 | 49 | 42 | 58 |
Figure S140. Get High-res Image Gene #30: 'amp_19q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0127 (Fisher's exact test), Q value = 0.038
Table S141. Gene #30: 'amp_19q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 30(19Q12) MUTATED | 32 | 43 | 26 | 36 | 27 |
| AMP PEAK 30(19Q12) WILD-TYPE | 57 | 56 | 67 | 34 | 27 |
Figure S141. Get High-res Image Gene #30: 'amp_19q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0281 (Fisher's exact test), Q value = 0.067
Table S142. Gene #30: 'amp_19q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 30(19Q12) MUTATED | 27 | 19 | 46 | 32 | 6 | 29 |
| AMP PEAK 30(19Q12) WILD-TYPE | 47 | 27 | 47 | 34 | 25 | 55 |
Figure S142. Get High-res Image Gene #30: 'amp_19q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S143. Gene #31: 'amp_19q13.43' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 31(19Q13.43) MUTATED | 35 | 82 | 19 | 18 |
| AMP PEAK 31(19Q13.43) WILD-TYPE | 134 | 58 | 40 | 22 |
Figure S143. Get High-res Image Gene #31: 'amp_19q13.43' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00073 (Fisher's exact test), Q value = 0.0036
Table S144. Gene #31: 'amp_19q13.43' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 31(19Q13.43) MUTATED | 39 | 61 | 22 | 32 |
| AMP PEAK 31(19Q13.43) WILD-TYPE | 99 | 55 | 47 | 53 |
Figure S144. Get High-res Image Gene #31: 'amp_19q13.43' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00314 (Fisher's exact test), Q value = 0.012
Table S145. Gene #31: 'amp_19q13.43' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 31(19Q13.43) MUTATED | 30 | 43 | 24 | 38 | 19 |
| AMP PEAK 31(19Q13.43) WILD-TYPE | 59 | 56 | 69 | 32 | 35 |
Figure S145. Get High-res Image Gene #31: 'amp_19q13.43' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0332 (Fisher's exact test), Q value = 0.078
Table S146. Gene #31: 'amp_19q13.43' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| AMP PEAK 31(19Q13.43) MUTATED | 32 | 24 | 55 | 39 |
| AMP PEAK 31(19Q13.43) WILD-TYPE | 66 | 19 | 79 | 80 |
Figure S146. Get High-res Image Gene #31: 'amp_19q13.43' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00481 (Fisher's exact test), Q value = 0.018
Table S147. Gene #31: 'amp_19q13.43' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 31(19Q13.43) MUTATED | 22 | 24 | 47 | 24 | 7 | 26 |
| AMP PEAK 31(19Q13.43) WILD-TYPE | 52 | 22 | 46 | 42 | 24 | 58 |
Figure S147. Get High-res Image Gene #31: 'amp_19q13.43' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S148. Gene #32: 'amp_20q11.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 32(20Q11.21) MUTATED | 73 | 108 | 47 | 34 |
| AMP PEAK 32(20Q11.21) WILD-TYPE | 96 | 32 | 12 | 6 |
Figure S148. Get High-res Image Gene #32: 'amp_20q11.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0078 (Fisher's exact test), Q value = 0.026
Table S149. Gene #32: 'amp_20q11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 32(20Q11.21) MUTATED | 82 | 88 | 37 | 55 |
| AMP PEAK 32(20Q11.21) WILD-TYPE | 56 | 28 | 32 | 30 |
Figure S149. Get High-res Image Gene #32: 'amp_20q11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0319 (Fisher's exact test), Q value = 0.075
Table S150. Gene #32: 'amp_20q11.21' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| AMP PEAK 32(20Q11.21) MUTATED | 22 | 28 | 17 | 16 |
| AMP PEAK 32(20Q11.21) WILD-TYPE | 20 | 10 | 9 | 2 |
Figure S150. Get High-res Image Gene #32: 'amp_20q11.21' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0421 (Fisher's exact test), Q value = 0.092
Table S151. Gene #32: 'amp_20q11.21' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| AMP PEAK 32(20Q11.21) MUTATED | 86 | 64 | 110 |
| AMP PEAK 32(20Q11.21) WILD-TYPE | 32 | 48 | 64 |
Figure S151. Get High-res Image Gene #32: 'amp_20q11.21' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0416 (Fisher's exact test), Q value = 0.092
Table S152. Gene #32: 'amp_20q11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| AMP PEAK 32(20Q11.21) MUTATED | 53 | 71 | 51 | 52 | 35 |
| AMP PEAK 32(20Q11.21) WILD-TYPE | 36 | 28 | 42 | 18 | 19 |
Figure S152. Get High-res Image Gene #32: 'amp_20q11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0011 (Fisher's exact test), Q value = 0.005
Table S153. Gene #32: 'amp_20q11.21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 32(20Q11.21) MUTATED | 48 | 34 | 69 | 46 | 10 | 51 |
| AMP PEAK 32(20Q11.21) WILD-TYPE | 26 | 12 | 24 | 20 | 21 | 33 |
Figure S153. Get High-res Image Gene #32: 'amp_20q11.21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S154. Gene #33: 'amp_22q12.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| AMP PEAK 33(22Q12.2) MUTATED | 19 | 48 | 9 | 11 |
| AMP PEAK 33(22Q12.2) WILD-TYPE | 150 | 92 | 50 | 29 |
Figure S154. Get High-res Image Gene #33: 'amp_22q12.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0183 (Fisher's exact test), Q value = 0.05
Table S155. Gene #33: 'amp_22q12.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| AMP PEAK 33(22Q12.2) MUTATED | 20 | 35 | 12 | 20 |
| AMP PEAK 33(22Q12.2) WILD-TYPE | 118 | 81 | 57 | 65 |
Figure S155. Get High-res Image Gene #33: 'amp_22q12.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00995 (Fisher's exact test), Q value = 0.031
Table S156. Gene #33: 'amp_22q12.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| AMP PEAK 33(22Q12.2) MUTATED | 22 | 50 | 14 |
| AMP PEAK 33(22Q12.2) WILD-TYPE | 94 | 130 | 94 |
Figure S156. Get High-res Image Gene #33: 'amp_22q12.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.048 (Fisher's exact test), Q value = 0.1
Table S157. Gene #33: 'amp_22q12.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| AMP PEAK 33(22Q12.2) MUTATED | 17 | 10 | 29 | 10 | 2 | 17 |
| AMP PEAK 33(22Q12.2) WILD-TYPE | 57 | 36 | 64 | 56 | 29 | 67 |
Figure S157. Get High-res Image Gene #33: 'amp_22q12.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0242 (Fisher's exact test), Q value = 0.06
Table S158. Gene #34: 'del_1p36.11' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| DEL PEAK 1(1P36.11) MUTATED | 3 | 10 | 9 | 4 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 39 | 28 | 17 | 14 |
Figure S158. Get High-res Image Gene #34: 'del_1p36.11' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0479 (Fisher's exact test), Q value = 0.1
Table S159. Gene #34: 'del_1p36.11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 1(1P36.11) MUTATED | 20 | 30 | 16 | 18 | 6 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 69 | 69 | 77 | 52 | 48 |
Figure S159. Get High-res Image Gene #34: 'del_1p36.11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00429 (Fisher's exact test), Q value = 0.016
Table S160. Gene #35: 'del_1q32.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 2(1Q32.1) MUTATED | 18 | 36 | 12 | 5 |
| DEL PEAK 2(1Q32.1) WILD-TYPE | 151 | 104 | 47 | 35 |
Figure S160. Get High-res Image Gene #35: 'del_1q32.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0175 (Fisher's exact test), Q value = 0.048
Table S161. Gene #35: 'del_1q32.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 2(1Q32.1) MUTATED | 17 | 31 | 12 | 11 |
| DEL PEAK 2(1Q32.1) WILD-TYPE | 121 | 85 | 57 | 74 |
Figure S161. Get High-res Image Gene #35: 'del_1q32.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0486 (Fisher's exact test), Q value = 0.1
Table S162. Gene #35: 'del_1q32.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 2(1Q32.1) MUTATED | 28 | 20 | 22 |
| DEL PEAK 2(1Q32.1) WILD-TYPE | 90 | 92 | 152 |
Figure S162. Get High-res Image Gene #35: 'del_1q32.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00074 (Fisher's exact test), Q value = 0.0036
Table S163. Gene #36: 'del_2q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 3(2Q22.1) MUTATED | 37 | 60 | 22 | 15 |
| DEL PEAK 3(2Q22.1) WILD-TYPE | 132 | 80 | 37 | 25 |
Figure S163. Get High-res Image Gene #36: 'del_2q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0174 (Fisher's exact test), Q value = 0.048
Table S164. Gene #36: 'del_2q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 3(2Q22.1) MUTATED | 36 | 51 | 19 | 28 |
| DEL PEAK 3(2Q22.1) WILD-TYPE | 102 | 65 | 50 | 57 |
Figure S164. Get High-res Image Gene #36: 'del_2q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00899 (Fisher's exact test), Q value = 0.029
Table S165. Gene #36: 'del_2q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 3(2Q22.1) MUTATED | 20 | 16 | 43 | 20 | 4 | 24 |
| DEL PEAK 3(2Q22.1) WILD-TYPE | 54 | 30 | 50 | 46 | 27 | 60 |
Figure S165. Get High-res Image Gene #36: 'del_2q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S166. Gene #37: 'del_2q34' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 4(2Q34) MUTATED | 39 | 83 | 37 | 15 |
| DEL PEAK 4(2Q34) WILD-TYPE | 130 | 57 | 22 | 25 |
Figure S166. Get High-res Image Gene #37: 'del_2q34' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00074 (Fisher's exact test), Q value = 0.0036
Table S167. Gene #37: 'del_2q34' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 4(2Q34) MUTATED | 45 | 67 | 26 | 36 |
| DEL PEAK 4(2Q34) WILD-TYPE | 93 | 49 | 43 | 49 |
Figure S167. Get High-res Image Gene #37: 'del_2q34' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00047 (Fisher's exact test), Q value = 0.0024
Table S168. Gene #37: 'del_2q34' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 4(2Q34) MUTATED | 30 | 24 | 51 | 23 | 4 | 36 |
| DEL PEAK 4(2Q34) WILD-TYPE | 44 | 22 | 42 | 43 | 27 | 48 |
Figure S168. Get High-res Image Gene #37: 'del_2q34' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S169. Gene #38: 'del_2q37.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 5(2Q37.1) MUTATED | 51 | 100 | 38 | 19 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 118 | 40 | 21 | 21 |
Figure S169. Get High-res Image Gene #38: 'del_2q37.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00041
Table S170. Gene #38: 'del_2q37.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 5(2Q37.1) MUTATED | 52 | 75 | 31 | 50 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 86 | 41 | 38 | 35 |
Figure S170. Get High-res Image Gene #38: 'del_2q37.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0486 (Fisher's exact test), Q value = 0.1
Table S171. Gene #38: 'del_2q37.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 5(2Q37.1) MUTATED | 62 | 66 | 77 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 56 | 46 | 97 |
Figure S171. Get High-res Image Gene #38: 'del_2q37.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0138 (Fisher's exact test), Q value = 0.04
Table S172. Gene #38: 'del_2q37.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 5(2Q37.1) MUTATED | 51 | 60 | 96 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 69 | 36 | 93 |
Figure S172. Get High-res Image Gene #38: 'del_2q37.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0452 (Fisher's exact test), Q value = 0.098
Table S173. Gene #38: 'del_2q37.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 5(2Q37.1) MUTATED | 42 | 59 | 43 | 42 | 21 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 47 | 40 | 50 | 28 | 33 |
Figure S173. Get High-res Image Gene #38: 'del_2q37.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00438 (Fisher's exact test), Q value = 0.016
Table S174. Gene #38: 'del_2q37.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 5(2Q37.1) MUTATED | 34 | 27 | 61 | 33 | 9 | 38 |
| DEL PEAK 5(2Q37.1) WILD-TYPE | 40 | 19 | 32 | 33 | 22 | 46 |
Figure S174. Get High-res Image Gene #38: 'del_2q37.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00031 (Fisher's exact test), Q value = 0.0017
Table S175. Gene #39: 'del_3p14.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 6(3P14.2) MUTATED | 33 | 54 | 13 | 17 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 136 | 86 | 46 | 23 |
Figure S175. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0347 (Fisher's exact test), Q value = 0.08
Table S176. Gene #39: 'del_3p14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 37 | 29 | 34 | 5 | 19 |
| DEL PEAK 6(3P14.2) MUTATED | 6 | 9 | 16 | 1 | 9 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 31 | 20 | 18 | 4 | 10 |
Figure S176. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.017 (Fisher's exact test), Q value = 0.047
Table S177. Gene #39: 'del_3p14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| DEL PEAK 6(3P14.2) MUTATED | 7 | 14 | 10 | 10 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 35 | 24 | 16 | 8 |
Figure S177. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S178. Gene #39: 'del_3p14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 6(3P14.2) MUTATED | 22 | 35 | 58 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 94 | 145 | 50 |
Figure S178. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00041
Table S179. Gene #39: 'del_3p14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 6(3P14.2) MUTATED | 27 | 19 | 69 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 91 | 93 | 105 |
Figure S179. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S180. Gene #39: 'del_3p14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 6(3P14.2) MUTATED | 42 | 25 | 14 | 25 | 11 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 47 | 74 | 79 | 45 | 43 |
Figure S180. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00062
Table S181. Gene #39: 'del_3p14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 6(3P14.2) MUTATED | 47 | 10 | 31 | 27 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 51 | 33 | 103 | 92 |
Figure S181. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S182. Gene #39: 'del_3p14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 6(3P14.2) MUTATED | 11 | 12 | 29 | 26 | 1 | 36 |
| DEL PEAK 6(3P14.2) WILD-TYPE | 63 | 34 | 64 | 40 | 30 | 48 |
Figure S182. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S183. Gene #40: 'del_4q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 7(4Q22.1) MUTATED | 38 | 68 | 34 | 22 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 131 | 72 | 25 | 18 |
Figure S183. Get High-res Image Gene #40: 'del_4q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0218 (Fisher's exact test), Q value = 0.056
Table S184. Gene #40: 'del_4q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 7(4Q22.1) MUTATED | 47 | 59 | 53 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 69 | 121 | 55 |
Figure S184. Get High-res Image Gene #40: 'del_4q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00102 (Fisher's exact test), Q value = 0.0048
Table S185. Gene #40: 'del_4q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 7(4Q22.1) MUTATED | 53 | 28 | 78 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 65 | 84 | 96 |
Figure S185. Get High-res Image Gene #40: 'del_4q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00764 (Fisher's exact test), Q value = 0.026
Table S186. Gene #40: 'del_4q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 7(4Q22.1) MUTATED | 48 | 39 | 25 | 28 | 22 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 41 | 60 | 68 | 42 | 32 |
Figure S186. Get High-res Image Gene #40: 'del_4q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0248 (Fisher's exact test), Q value = 0.061
Table S187. Gene #40: 'del_4q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 7(4Q22.1) MUTATED | 48 | 12 | 44 | 52 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 50 | 31 | 90 | 67 |
Figure S187. Get High-res Image Gene #40: 'del_4q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0144 (Fisher's exact test), Q value = 0.042
Table S188. Gene #40: 'del_4q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 7(4Q22.1) MUTATED | 26 | 15 | 34 | 32 | 6 | 43 |
| DEL PEAK 7(4Q22.1) WILD-TYPE | 48 | 31 | 59 | 34 | 25 | 41 |
Figure S188. Get High-res Image Gene #40: 'del_4q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S189. Gene #41: 'del_4q34.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 8(4Q34.2) MUTATED | 36 | 81 | 40 | 20 |
| DEL PEAK 8(4Q34.2) WILD-TYPE | 133 | 59 | 19 | 20 |
Figure S189. Get High-res Image Gene #41: 'del_4q34.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0178 (Fisher's exact test), Q value = 0.049
Table S190. Gene #41: 'del_4q34.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 8(4Q34.2) MUTATED | 56 | 64 | 23 | 34 |
| DEL PEAK 8(4Q34.2) WILD-TYPE | 82 | 52 | 46 | 51 |
Figure S190. Get High-res Image Gene #41: 'del_4q34.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0418 (Fisher's exact test), Q value = 0.092
Table S191. Gene #41: 'del_4q34.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 8(4Q34.2) MUTATED | 55 | 37 | 82 |
| DEL PEAK 8(4Q34.2) WILD-TYPE | 63 | 75 | 92 |
Figure S191. Get High-res Image Gene #41: 'del_4q34.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00071 (Fisher's exact test), Q value = 0.0035
Table S192. Gene #41: 'del_4q34.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 8(4Q34.2) MUTATED | 27 | 20 | 45 | 33 | 3 | 42 |
| DEL PEAK 8(4Q34.2) WILD-TYPE | 47 | 26 | 48 | 33 | 28 | 42 |
Figure S192. Get High-res Image Gene #41: 'del_4q34.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S193. Gene #42: 'del_5q12.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 9(5Q12.1) MUTATED | 44 | 100 | 35 | 23 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 125 | 40 | 24 | 17 |
Figure S193. Get High-res Image Gene #42: 'del_5q12.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00046
Table S194. Gene #42: 'del_5q12.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 9(5Q12.1) MUTATED | 65 | 76 | 23 | 38 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 73 | 40 | 46 | 47 |
Figure S194. Get High-res Image Gene #42: 'del_5q12.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00489 (Fisher's exact test), Q value = 0.018
Table S195. Gene #42: 'del_5q12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 9(5Q12.1) MUTATED | 73 | 46 | 82 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 45 | 66 | 92 |
Figure S195. Get High-res Image Gene #42: 'del_5q12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0217 (Fisher's exact test), Q value = 0.056
Table S196. Gene #42: 'del_5q12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 9(5Q12.1) MUTATED | 62 | 58 | 82 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 58 | 38 | 107 |
Figure S196. Get High-res Image Gene #42: 'del_5q12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00056
Table S197. Gene #42: 'del_5q12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 9(5Q12.1) MUTATED | 42 | 60 | 28 | 43 | 29 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 47 | 39 | 65 | 27 | 25 |
Figure S197. Get High-res Image Gene #42: 'del_5q12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00115 (Fisher's exact test), Q value = 0.0052
Table S198. Gene #42: 'del_5q12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 9(5Q12.1) MUTATED | 37 | 31 | 50 | 38 | 6 | 37 |
| DEL PEAK 9(5Q12.1) WILD-TYPE | 37 | 15 | 43 | 28 | 25 | 47 |
Figure S198. Get High-res Image Gene #42: 'del_5q12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S199. Gene #43: 'del_6p25.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 10(6P25.3) MUTATED | 20 | 49 | 19 | 18 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 149 | 91 | 40 | 22 |
Figure S199. Get High-res Image Gene #43: 'del_6p25.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00061 (Fisher's exact test), Q value = 0.0031
Table S200. Gene #43: 'del_6p25.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 10(6P25.3) MUTATED | 26 | 47 | 16 | 17 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 112 | 69 | 53 | 68 |
Figure S200. Get High-res Image Gene #43: 'del_6p25.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0149 (Fisher's exact test), Q value = 0.042
Table S201. Gene #43: 'del_6p25.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 10(6P25.3) MUTATED | 42 | 26 | 36 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 76 | 86 | 138 |
Figure S201. Get High-res Image Gene #43: 'del_6p25.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0306 (Fisher's exact test), Q value = 0.072
Table S202. Gene #43: 'del_6p25.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 10(6P25.3) MUTATED | 22 | 30 | 14 | 25 | 14 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 67 | 69 | 79 | 45 | 40 |
Figure S202. Get High-res Image Gene #43: 'del_6p25.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00769 (Fisher's exact test), Q value = 0.026
Table S203. Gene #43: 'del_6p25.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 10(6P25.3) MUTATED | 17 | 16 | 30 | 20 | 1 | 19 |
| DEL PEAK 10(6P25.3) WILD-TYPE | 57 | 30 | 63 | 46 | 30 | 65 |
Figure S203. Get High-res Image Gene #43: 'del_6p25.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S204. Gene #44: 'del_6q21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 11(6Q21) MUTATED | 44 | 94 | 25 | 27 |
| DEL PEAK 11(6Q21) WILD-TYPE | 125 | 46 | 34 | 13 |
Figure S204. Get High-res Image Gene #44: 'del_6q21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.052
Table S205. Gene #44: 'del_6q21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 11(6Q21) MUTATED | 54 | 67 | 28 | 41 |
| DEL PEAK 11(6Q21) WILD-TYPE | 84 | 49 | 41 | 44 |
Figure S205. Get High-res Image Gene #44: 'del_6q21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0158 (Fisher's exact test), Q value = 0.045
Table S206. Gene #44: 'del_6q21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 11(6Q21) MUTATED | 59 | 55 | 75 |
| DEL PEAK 11(6Q21) WILD-TYPE | 61 | 41 | 114 |
Figure S206. Get High-res Image Gene #44: 'del_6q21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.00097
Table S207. Gene #44: 'del_6q21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 11(6Q21) MUTATED | 36 | 60 | 27 | 39 | 27 |
| DEL PEAK 11(6Q21) WILD-TYPE | 53 | 39 | 66 | 31 | 27 |
Figure S207. Get High-res Image Gene #44: 'del_6q21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S208. Gene #44: 'del_6q21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 11(6Q21) MUTATED | 30 | 30 | 54 | 37 | 4 | 32 |
| DEL PEAK 11(6Q21) WILD-TYPE | 44 | 16 | 39 | 29 | 27 | 52 |
Figure S208. Get High-res Image Gene #44: 'del_6q21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S209. Gene #45: 'del_6q27' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 12(6Q27) MUTATED | 43 | 93 | 26 | 28 |
| DEL PEAK 12(6Q27) WILD-TYPE | 126 | 47 | 33 | 12 |
Figure S209. Get High-res Image Gene #45: 'del_6q27' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.027 (Fisher's exact test), Q value = 0.064
Table S210. Gene #45: 'del_6q27' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 12(6Q27) MUTATED | 54 | 67 | 30 | 39 |
| DEL PEAK 12(6Q27) WILD-TYPE | 84 | 49 | 39 | 46 |
Figure S210. Get High-res Image Gene #45: 'del_6q27' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0101 (Fisher's exact test), Q value = 0.032
Table S211. Gene #45: 'del_6q27' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 12(6Q27) MUTATED | 69 | 47 | 73 |
| DEL PEAK 12(6Q27) WILD-TYPE | 49 | 65 | 101 |
Figure S211. Get High-res Image Gene #45: 'del_6q27' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0228 (Fisher's exact test), Q value = 0.057
Table S212. Gene #45: 'del_6q27' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 12(6Q27) MUTATED | 58 | 55 | 76 |
| DEL PEAK 12(6Q27) WILD-TYPE | 62 | 41 | 113 |
Figure S212. Get High-res Image Gene #45: 'del_6q27' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00041
Table S213. Gene #45: 'del_6q27' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 12(6Q27) MUTATED | 33 | 57 | 28 | 44 | 27 |
| DEL PEAK 12(6Q27) WILD-TYPE | 56 | 42 | 65 | 26 | 27 |
Figure S213. Get High-res Image Gene #45: 'del_6q27' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S214. Gene #45: 'del_6q27' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 12(6Q27) MUTATED | 33 | 28 | 55 | 38 | 3 | 30 |
| DEL PEAK 12(6Q27) WILD-TYPE | 41 | 18 | 38 | 28 | 28 | 54 |
Figure S214. Get High-res Image Gene #45: 'del_6q27' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.00088
Table S215. Gene #46: 'del_7q36.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 13(7Q36.3) MUTATED | 10 | 30 | 11 | 9 |
| DEL PEAK 13(7Q36.3) WILD-TYPE | 159 | 110 | 48 | 31 |
Figure S215. Get High-res Image Gene #46: 'del_7q36.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00143 (Fisher's exact test), Q value = 0.0062
Table S216. Gene #46: 'del_7q36.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 13(7Q36.3) MUTATED | 14 | 16 | 7 | 20 | 3 |
| DEL PEAK 13(7Q36.3) WILD-TYPE | 75 | 83 | 86 | 50 | 51 |
Figure S216. Get High-res Image Gene #46: 'del_7q36.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00373 (Fisher's exact test), Q value = 0.014
Table S217. Gene #46: 'del_7q36.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 13(7Q36.3) MUTATED | 3 | 7 | 20 | 13 | 1 | 16 |
| DEL PEAK 13(7Q36.3) WILD-TYPE | 71 | 39 | 73 | 53 | 30 | 68 |
Figure S217. Get High-res Image Gene #46: 'del_7q36.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S218. Gene #47: 'del_8p23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 14(8P23.3) MUTATED | 64 | 119 | 46 | 13 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 105 | 21 | 13 | 27 |
Figure S218. Get High-res Image Gene #47: 'del_8p23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S219. Gene #47: 'del_8p23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 14(8P23.3) MUTATED | 88 | 89 | 26 | 39 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 50 | 27 | 43 | 46 |
Figure S219. Get High-res Image Gene #47: 'del_8p23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00085
Table S220. Gene #47: 'del_8p23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 14(8P23.3) MUTATED | 85 | 50 | 106 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 33 | 62 | 68 |
Figure S220. Get High-res Image Gene #47: 'del_8p23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0135 (Fisher's exact test), Q value = 0.04
Table S221. Gene #47: 'del_8p23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 14(8P23.3) MUTATED | 49 | 69 | 44 | 41 | 37 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 40 | 30 | 49 | 29 | 17 |
Figure S221. Get High-res Image Gene #47: 'del_8p23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00178 (Fisher's exact test), Q value = 0.0074
Table S222. Gene #47: 'del_8p23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 14(8P23.3) MUTATED | 46 | 30 | 59 | 40 | 7 | 53 |
| DEL PEAK 14(8P23.3) WILD-TYPE | 28 | 16 | 34 | 26 | 24 | 31 |
Figure S222. Get High-res Image Gene #47: 'del_8p23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S223. Gene #48: 'del_8p21.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 15(8P21.3) MUTATED | 66 | 126 | 46 | 14 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 103 | 14 | 13 | 26 |
Figure S223. Get High-res Image Gene #48: 'del_8p21.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S224. Gene #48: 'del_8p21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 15(8P21.3) MUTATED | 90 | 89 | 31 | 42 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 48 | 27 | 38 | 43 |
Figure S224. Get High-res Image Gene #48: 'del_8p21.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00908 (Fisher's exact test), Q value = 0.029
Table S225. Gene #48: 'del_8p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 15(8P21.3) MUTATED | 83 | 57 | 111 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 35 | 55 | 63 |
Figure S225. Get High-res Image Gene #48: 'del_8p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0174 (Fisher's exact test), Q value = 0.048
Table S226. Gene #48: 'del_8p21.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 15(8P21.3) MUTATED | 70 | 71 | 109 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 50 | 25 | 80 |
Figure S226. Get High-res Image Gene #48: 'del_8p21.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00831 (Fisher's exact test), Q value = 0.027
Table S227. Gene #48: 'del_8p21.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 15(8P21.3) MUTATED | 49 | 75 | 49 | 42 | 35 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 40 | 24 | 44 | 28 | 19 |
Figure S227. Get High-res Image Gene #48: 'del_8p21.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 8e-04 (Fisher's exact test), Q value = 0.0038
Table S228. Gene #48: 'del_8p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 15(8P21.3) MUTATED | 45 | 33 | 64 | 39 | 8 | 56 |
| DEL PEAK 15(8P21.3) WILD-TYPE | 29 | 13 | 29 | 27 | 23 | 28 |
Figure S228. Get High-res Image Gene #48: 'del_8p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S229. Gene #49: 'del_9p23' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 16(9P23) MUTATED | 82 | 75 | 2 | 19 |
| DEL PEAK 16(9P23) WILD-TYPE | 87 | 65 | 57 | 21 |
Figure S229. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0014
Table S230. Gene #49: 'del_9p23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 16(9P23) MUTATED | 40 | 60 | 37 | 41 |
| DEL PEAK 16(9P23) WILD-TYPE | 98 | 56 | 32 | 44 |
Figure S230. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0244 (Fisher's exact test), Q value = 0.06
Table S231. Gene #49: 'del_9p23' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 16(9P23) MUTATED | 48 | 92 | 38 |
| DEL PEAK 16(9P23) WILD-TYPE | 68 | 88 | 70 |
Figure S231. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00024 (Fisher's exact test), Q value = 0.0013
Table S232. Gene #49: 'del_9p23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 16(9P23) MUTATED | 62 | 60 | 56 |
| DEL PEAK 16(9P23) WILD-TYPE | 56 | 52 | 118 |
Figure S232. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0445 (Fisher's exact test), Q value = 0.096
Table S233. Gene #49: 'del_9p23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 16(9P23) MUTATED | 45 | 52 | 80 |
| DEL PEAK 16(9P23) WILD-TYPE | 75 | 44 | 109 |
Figure S233. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0146 (Fisher's exact test), Q value = 0.042
Table S234. Gene #49: 'del_9p23' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 16(9P23) MUTATED | 28 | 49 | 38 | 40 | 22 |
| DEL PEAK 16(9P23) WILD-TYPE | 61 | 50 | 55 | 30 | 32 |
Figure S234. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S235. Gene #49: 'del_9p23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 16(9P23) MUTATED | 22 | 26 | 69 | 56 |
| DEL PEAK 16(9P23) WILD-TYPE | 76 | 17 | 65 | 63 |
Figure S235. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0024
Table S236. Gene #49: 'del_9p23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 16(9P23) MUTATED | 27 | 26 | 43 | 37 | 18 | 22 |
| DEL PEAK 16(9P23) WILD-TYPE | 47 | 20 | 50 | 29 | 13 | 62 |
Figure S236. Get High-res Image Gene #49: 'del_9p23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S237. Gene #50: 'del_9p21.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 17(9P21.3) MUTATED | 118 | 89 | 7 | 25 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 51 | 51 | 52 | 15 |
Figure S237. Get High-res Image Gene #50: 'del_9p21.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0101 (Fisher's exact test), Q value = 0.032
Table S238. Gene #50: 'del_9p21.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| DEL PEAK 17(9P21.3) MUTATED | 33 | 17 | 14 | 13 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 9 | 21 | 12 | 5 |
Figure S238. Get High-res Image Gene #50: 'del_9p21.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0371 (Fisher's exact test), Q value = 0.084
Table S239. Gene #50: 'del_9p21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 17(9P21.3) MUTATED | 58 | 117 | 63 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 58 | 63 | 45 |
Figure S239. Get High-res Image Gene #50: 'del_9p21.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.057
Table S240. Gene #50: 'del_9p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 17(9P21.3) MUTATED | 75 | 74 | 89 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 43 | 38 | 85 |
Figure S240. Get High-res Image Gene #50: 'del_9p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0373 (Fisher's exact test), Q value = 0.084
Table S241. Gene #50: 'del_9p21.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 17(9P21.3) MUTATED | 47 | 30 | 86 | 69 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 51 | 13 | 48 | 50 |
Figure S241. Get High-res Image Gene #50: 'del_9p21.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00041
Table S242. Gene #50: 'del_9p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 17(9P21.3) MUTATED | 34 | 33 | 52 | 49 | 25 | 39 |
| DEL PEAK 17(9P21.3) WILD-TYPE | 40 | 13 | 41 | 17 | 6 | 45 |
Figure S242. Get High-res Image Gene #50: 'del_9p21.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S243. Gene #51: 'del_9q22.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 18(9Q22.33) MUTATED | 82 | 67 | 8 | 21 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 87 | 73 | 51 | 19 |
Figure S243. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S244. Gene #51: 'del_9q22.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 18(9Q22.33) MUTATED | 35 | 61 | 38 | 44 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 103 | 55 | 31 | 41 |
Figure S244. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00596 (Fisher's exact test), Q value = 0.021
Table S245. Gene #51: 'del_9q22.33' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| DEL PEAK 18(9Q22.33) MUTATED | 26 | 14 | 9 | 3 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 16 | 24 | 17 | 15 |
Figure S245. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S246. Gene #51: 'del_9q22.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 18(9Q22.33) MUTATED | 42 | 107 | 29 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 74 | 73 | 79 |
Figure S246. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S247. Gene #51: 'del_9q22.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 18(9Q22.33) MUTATED | 64 | 68 | 46 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 54 | 44 | 128 |
Figure S247. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00845 (Fisher's exact test), Q value = 0.028
Table S248. Gene #51: 'del_9q22.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 18(9Q22.33) MUTATED | 39 | 50 | 88 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 81 | 46 | 101 |
Figure S248. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00056
Table S249. Gene #51: 'del_9q22.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 18(9Q22.33) MUTATED | 21 | 45 | 46 | 41 | 24 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 68 | 54 | 47 | 29 | 30 |
Figure S249. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S250. Gene #51: 'del_9q22.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 18(9Q22.33) MUTATED | 19 | 25 | 80 | 49 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 79 | 18 | 54 | 70 |
Figure S250. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S251. Gene #51: 'del_9q22.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 18(9Q22.33) MUTATED | 29 | 25 | 48 | 34 | 25 | 12 |
| DEL PEAK 18(9Q22.33) WILD-TYPE | 45 | 21 | 45 | 32 | 6 | 72 |
Figure S251. Get High-res Image Gene #51: 'del_9q22.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00166 (Fisher's exact test), Q value = 0.0071
Table S252. Gene #52: 'del_10p11.21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 19(10P11.21) MUTATED | 11 | 31 | 30 |
| DEL PEAK 19(10P11.21) WILD-TYPE | 105 | 149 | 78 |
Figure S252. Get High-res Image Gene #52: 'del_10p11.21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S253. Gene #53: 'del_10q23.31' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 20(10Q23.31) MUTATED | 34 | 80 | 34 | 18 |
| DEL PEAK 20(10Q23.31) WILD-TYPE | 135 | 60 | 25 | 22 |
Figure S253. Get High-res Image Gene #53: 'del_10q23.31' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00136 (Fisher's exact test), Q value = 0.006
Table S254. Gene #53: 'del_10q23.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 20(10Q23.31) MUTATED | 46 | 65 | 23 | 32 |
| DEL PEAK 20(10Q23.31) WILD-TYPE | 92 | 51 | 46 | 53 |
Figure S254. Get High-res Image Gene #53: 'del_10q23.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0455 (Fisher's exact test), Q value = 0.098
Table S255. Gene #53: 'del_10q23.31' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 20(10Q23.31) MUTATED | 36 | 81 | 46 |
| DEL PEAK 20(10Q23.31) WILD-TYPE | 80 | 99 | 62 |
Figure S255. Get High-res Image Gene #53: 'del_10q23.31' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S256. Gene #54: 'del_11p15.5' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 21(11P15.5) MUTATED | 66 | 102 | 18 | 25 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 103 | 38 | 41 | 15 |
Figure S256. Get High-res Image Gene #54: 'del_11p15.5' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00093
Table S257. Gene #54: 'del_11p15.5' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 21(11P15.5) MUTATED | 51 | 71 | 44 | 45 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 87 | 45 | 25 | 40 |
Figure S257. Get High-res Image Gene #54: 'del_11p15.5' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00166 (Fisher's exact test), Q value = 0.0071
Table S258. Gene #54: 'del_11p15.5' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 21(11P15.5) MUTATED | 54 | 110 | 44 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 62 | 70 | 64 |
Figure S258. Get High-res Image Gene #54: 'del_11p15.5' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S259. Gene #54: 'del_11p15.5' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 21(11P15.5) MUTATED | 76 | 66 | 66 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 42 | 46 | 108 |
Figure S259. Get High-res Image Gene #54: 'del_11p15.5' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0215 (Fisher's exact test), Q value = 0.056
Table S260. Gene #54: 'del_11p15.5' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 21(11P15.5) MUTATED | 54 | 61 | 95 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 66 | 35 | 94 |
Figure S260. Get High-res Image Gene #54: 'del_11p15.5' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0135 (Fisher's exact test), Q value = 0.04
Table S261. Gene #54: 'del_11p15.5' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 21(11P15.5) MUTATED | 37 | 25 | 75 | 68 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 61 | 18 | 59 | 51 |
Figure S261. Get High-res Image Gene #54: 'del_11p15.5' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0125 (Fisher's exact test), Q value = 0.037
Table S262. Gene #54: 'del_11p15.5' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 21(11P15.5) MUTATED | 40 | 29 | 54 | 37 | 16 | 29 |
| DEL PEAK 21(11P15.5) WILD-TYPE | 34 | 17 | 39 | 29 | 15 | 55 |
Figure S262. Get High-res Image Gene #54: 'del_11p15.5' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00182 (Fisher's exact test), Q value = 0.0075
Table S263. Gene #55: 'del_11q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 22(11Q23.3) MUTATED | 50 | 66 | 18 | 21 |
| DEL PEAK 22(11Q23.3) WILD-TYPE | 119 | 74 | 41 | 19 |
Figure S263. Get High-res Image Gene #55: 'del_11q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00046
Table S264. Gene #56: 'del_11q25' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 23(11Q25) MUTATED | 42 | 65 | 16 | 20 |
| DEL PEAK 23(11Q25) WILD-TYPE | 127 | 75 | 43 | 20 |
Figure S264. Get High-res Image Gene #56: 'del_11q25' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.033
Table S265. Gene #57: 'del_12p13.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 24(12P13.1) MUTATED | 19 | 35 | 7 | 7 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 150 | 105 | 52 | 33 |
Figure S265. Get High-res Image Gene #57: 'del_12p13.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00071 (Fisher's exact test), Q value = 0.0035
Table S266. Gene #57: 'del_12p13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 24(12P13.1) MUTATED | 13 | 33 | 11 | 11 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 125 | 83 | 58 | 74 |
Figure S266. Get High-res Image Gene #57: 'del_12p13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0063 (Fisher's exact test), Q value = 0.022
Table S267. Gene #57: 'del_12p13.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 24(12P13.1) MUTATED | 21 | 38 | 8 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 95 | 142 | 100 |
Figure S267. Get High-res Image Gene #57: 'del_12p13.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00029
Table S268. Gene #57: 'del_12p13.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 24(12P13.1) MUTATED | 34 | 18 | 15 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 84 | 94 | 159 |
Figure S268. Get High-res Image Gene #57: 'del_12p13.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0167 (Fisher's exact test), Q value = 0.047
Table S269. Gene #57: 'del_12p13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 24(12P13.1) MUTATED | 7 | 9 | 27 | 24 |
| DEL PEAK 24(12P13.1) WILD-TYPE | 91 | 34 | 107 | 95 |
Figure S269. Get High-res Image Gene #57: 'del_12p13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S270. Gene #58: 'del_12q24.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 25(12Q24.33) MUTATED | 17 | 41 | 20 | 10 |
| DEL PEAK 25(12Q24.33) WILD-TYPE | 152 | 99 | 39 | 30 |
Figure S270. Get High-res Image Gene #58: 'del_12q24.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S271. Gene #59: 'del_13q14.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 26(13Q14.2) MUTATED | 24 | 69 | 43 | 20 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 145 | 71 | 16 | 20 |
Figure S271. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00754 (Fisher's exact test), Q value = 0.026
Table S272. Gene #59: 'del_13q14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 37 | 29 | 34 | 5 | 19 |
| DEL PEAK 26(13Q14.2) MUTATED | 10 | 13 | 22 | 1 | 5 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 27 | 16 | 12 | 4 | 14 |
Figure S272. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00337 (Fisher's exact test), Q value = 0.013
Table S273. Gene #59: 'del_13q14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| DEL PEAK 26(13Q14.2) MUTATED | 11 | 17 | 18 | 5 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 31 | 21 | 8 | 13 |
Figure S273. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0223 (Fisher's exact test), Q value = 0.057
Table S274. Gene #59: 'del_13q14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 26(13Q14.2) MUTATED | 46 | 56 | 51 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 70 | 124 | 57 |
Figure S274. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0108 (Fisher's exact test), Q value = 0.033
Table S275. Gene #59: 'del_13q14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 26(13Q14.2) MUTATED | 43 | 31 | 79 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 75 | 81 | 95 |
Figure S275. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0014
Table S276. Gene #59: 'del_13q14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 26(13Q14.2) MUTATED | 47 | 42 | 21 | 30 | 16 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 42 | 57 | 72 | 40 | 38 |
Figure S276. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00583 (Fisher's exact test), Q value = 0.021
Table S277. Gene #59: 'del_13q14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 26(13Q14.2) MUTATED | 52 | 14 | 52 | 36 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 46 | 29 | 82 | 83 |
Figure S277. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S278. Gene #59: 'del_13q14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 26(13Q14.2) MUTATED | 17 | 18 | 48 | 21 | 3 | 47 |
| DEL PEAK 26(13Q14.2) WILD-TYPE | 57 | 28 | 45 | 45 | 28 | 37 |
Figure S278. Get High-res Image Gene #59: 'del_13q14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S279. Gene #60: 'del_14q24.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 27(14Q24.1) MUTATED | 32 | 83 | 12 | 10 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 137 | 57 | 47 | 30 |
Figure S279. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S280. Gene #60: 'del_14q24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 27(14Q24.1) MUTATED | 35 | 63 | 25 | 14 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 103 | 53 | 44 | 71 |
Figure S280. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00662 (Fisher's exact test), Q value = 0.023
Table S281. Gene #60: 'del_14q24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 27(14Q24.1) MUTATED | 37 | 74 | 25 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 79 | 106 | 83 |
Figure S281. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S282. Gene #60: 'del_14q24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 27(14Q24.1) MUTATED | 64 | 35 | 37 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 54 | 77 | 137 |
Figure S282. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00666 (Fisher's exact test), Q value = 0.023
Table S283. Gene #60: 'del_14q24.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 27(14Q24.1) MUTATED | 37 | 45 | 54 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 83 | 51 | 135 |
Figure S283. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00075 (Fisher's exact test), Q value = 0.0036
Table S284. Gene #60: 'del_14q24.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 27(14Q24.1) MUTATED | 22 | 40 | 20 | 34 | 20 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 67 | 59 | 73 | 36 | 34 |
Figure S284. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00356 (Fisher's exact test), Q value = 0.014
Table S285. Gene #60: 'del_14q24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 27(14Q24.1) MUTATED | 23 | 23 | 42 | 46 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 75 | 20 | 92 | 73 |
Figure S285. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00017
Table S286. Gene #60: 'del_14q24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 27(14Q24.1) MUTATED | 22 | 22 | 40 | 31 | 3 | 16 |
| DEL PEAK 27(14Q24.1) WILD-TYPE | 52 | 24 | 53 | 35 | 28 | 68 |
Figure S286. Get High-res Image Gene #60: 'del_14q24.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S287. Gene #61: 'del_15q13.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 28(15Q13.1) MUTATED | 23 | 80 | 39 | 18 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 146 | 60 | 20 | 22 |
Figure S287. Get High-res Image Gene #61: 'del_15q13.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00041
Table S288. Gene #61: 'del_15q13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 28(15Q13.1) MUTATED | 55 | 64 | 16 | 25 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 83 | 52 | 53 | 60 |
Figure S288. Get High-res Image Gene #61: 'del_15q13.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.015 (Fisher's exact test), Q value = 0.043
Table S289. Gene #61: 'del_15q13.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 28(15Q13.1) MUTATED | 41 | 50 | 69 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 79 | 46 | 120 |
Figure S289. Get High-res Image Gene #61: 'del_15q13.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00051
Table S290. Gene #61: 'del_15q13.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 28(15Q13.1) MUTATED | 30 | 52 | 21 | 37 | 20 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 59 | 47 | 72 | 33 | 34 |
Figure S290. Get High-res Image Gene #61: 'del_15q13.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0125 (Fisher's exact test), Q value = 0.037
Table S291. Gene #61: 'del_15q13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 28(15Q13.1) MUTATED | 43 | 26 | 48 | 40 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 55 | 17 | 86 | 79 |
Figure S291. Get High-res Image Gene #61: 'del_15q13.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S292. Gene #61: 'del_15q13.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 28(15Q13.1) MUTATED | 24 | 26 | 45 | 24 | 1 | 37 |
| DEL PEAK 28(15Q13.1) WILD-TYPE | 50 | 20 | 48 | 42 | 30 | 47 |
Figure S292. Get High-res Image Gene #61: 'del_15q13.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S293. Gene #62: 'del_16p13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 29(16P13.3) MUTATED | 30 | 82 | 45 | 17 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 139 | 58 | 14 | 23 |
Figure S293. Get High-res Image Gene #62: 'del_16p13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0014 (Fisher's exact test), Q value = 0.0062
Table S294. Gene #62: 'del_16p13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 29(16P13.3) MUTATED | 55 | 65 | 19 | 35 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 83 | 51 | 50 | 50 |
Figure S294. Get High-res Image Gene #62: 'del_16p13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0374 (Fisher's exact test), Q value = 0.084
Table S295. Gene #62: 'del_16p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 29(16P13.3) MUTATED | 39 | 47 | 28 | 37 | 22 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 50 | 52 | 65 | 33 | 32 |
Figure S295. Get High-res Image Gene #62: 'del_16p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.013 (Fisher's exact test), Q value = 0.038
Table S296. Gene #62: 'del_16p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 29(16P13.3) MUTATED | 29 | 19 | 46 | 24 | 6 | 45 |
| DEL PEAK 29(16P13.3) WILD-TYPE | 45 | 27 | 47 | 42 | 25 | 39 |
Figure S296. Get High-res Image Gene #62: 'del_16p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S297. Gene #63: 'del_16q23.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 30(16Q23.1) MUTATED | 14 | 50 | 36 | 19 |
| DEL PEAK 30(16Q23.1) WILD-TYPE | 155 | 90 | 23 | 21 |
Figure S297. Get High-res Image Gene #63: 'del_16q23.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00232 (Fisher's exact test), Q value = 0.0094
Table S298. Gene #63: 'del_16q23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 30(16Q23.1) MUTATED | 37 | 46 | 10 | 26 |
| DEL PEAK 30(16Q23.1) WILD-TYPE | 101 | 70 | 59 | 59 |
Figure S298. Get High-res Image Gene #63: 'del_16q23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0254 (Fisher's exact test), Q value = 0.062
Table S299. Gene #63: 'del_16q23.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 30(16Q23.1) MUTATED | 28 | 32 | 19 | 29 | 11 |
| DEL PEAK 30(16Q23.1) WILD-TYPE | 61 | 67 | 74 | 41 | 43 |
Figure S299. Get High-res Image Gene #63: 'del_16q23.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00041
Table S300. Gene #63: 'del_16q23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 30(16Q23.1) MUTATED | 12 | 15 | 37 | 15 | 2 | 34 |
| DEL PEAK 30(16Q23.1) WILD-TYPE | 62 | 31 | 56 | 51 | 29 | 50 |
Figure S300. Get High-res Image Gene #63: 'del_16q23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S301. Gene #64: 'del_17p12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 31(17P12) MUTATED | 61 | 93 | 26 | 29 |
| DEL PEAK 31(17P12) WILD-TYPE | 108 | 47 | 33 | 11 |
Figure S301. Get High-res Image Gene #64: 'del_17p12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00112 (Fisher's exact test), Q value = 0.0051
Table S302. Gene #64: 'del_17p12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 31(17P12) MUTATED | 60 | 76 | 37 | 36 |
| DEL PEAK 31(17P12) WILD-TYPE | 78 | 40 | 32 | 49 |
Figure S302. Get High-res Image Gene #64: 'del_17p12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00944 (Fisher's exact test), Q value = 0.03
Table S303. Gene #64: 'del_17p12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 31(17P12) MUTATED | 74 | 53 | 79 |
| DEL PEAK 31(17P12) WILD-TYPE | 44 | 59 | 95 |
Figure S303. Get High-res Image Gene #64: 'del_17p12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00028 (Fisher's exact test), Q value = 0.0015
Table S304. Gene #64: 'del_17p12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 31(17P12) MUTATED | 43 | 51 | 34 | 51 | 28 |
| DEL PEAK 31(17P12) WILD-TYPE | 46 | 48 | 59 | 19 | 26 |
Figure S304. Get High-res Image Gene #64: 'del_17p12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00051
Table S305. Gene #64: 'del_17p12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 31(17P12) MUTATED | 32 | 26 | 60 | 41 | 7 | 36 |
| DEL PEAK 31(17P12) WILD-TYPE | 42 | 20 | 33 | 25 | 24 | 48 |
Figure S305. Get High-res Image Gene #64: 'del_17p12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00023
Table S306. Gene #65: 'del_18q23' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 32(18Q23) MUTATED | 53 | 82 | 28 | 17 |
| DEL PEAK 32(18Q23) WILD-TYPE | 116 | 58 | 31 | 23 |
Figure S306. Get High-res Image Gene #65: 'del_18q23' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S307. Gene #65: 'del_18q23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 120 | 96 | 189 |
| DEL PEAK 32(18Q23) MUTATED | 53 | 64 | 62 |
| DEL PEAK 32(18Q23) WILD-TYPE | 67 | 32 | 127 |
Figure S307. Get High-res Image Gene #65: 'del_18q23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S308. Gene #65: 'del_18q23' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 32(18Q23) MUTATED | 29 | 73 | 29 | 28 | 20 |
| DEL PEAK 32(18Q23) WILD-TYPE | 60 | 26 | 64 | 42 | 34 |
Figure S308. Get High-res Image Gene #65: 'del_18q23' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00601 (Fisher's exact test), Q value = 0.021
Table S309. Gene #65: 'del_18q23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 32(18Q23) MUTATED | 42 | 30 | 53 | 53 |
| DEL PEAK 32(18Q23) WILD-TYPE | 56 | 13 | 81 | 66 |
Figure S309. Get High-res Image Gene #65: 'del_18q23' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00111 (Fisher's exact test), Q value = 0.005
Table S310. Gene #65: 'del_18q23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 32(18Q23) MUTATED | 33 | 34 | 40 | 25 | 9 | 37 |
| DEL PEAK 32(18Q23) WILD-TYPE | 41 | 12 | 53 | 41 | 22 | 47 |
Figure S310. Get High-res Image Gene #65: 'del_18q23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S311. Gene #66: 'del_19p13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 33(19P13.3) MUTATED | 35 | 74 | 16 | 21 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 134 | 66 | 43 | 19 |
Figure S311. Get High-res Image Gene #66: 'del_19p13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0336 (Fisher's exact test), Q value = 0.078
Table S312. Gene #66: 'del_19p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 33(19P13.3) MUTATED | 41 | 54 | 49 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 75 | 126 | 59 |
Figure S312. Get High-res Image Gene #66: 'del_19p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.0074
Table S313. Gene #66: 'del_19p13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 33(19P13.3) MUTATED | 49 | 25 | 70 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 69 | 87 | 104 |
Figure S313. Get High-res Image Gene #66: 'del_19p13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00627 (Fisher's exact test), Q value = 0.022
Table S314. Gene #66: 'del_19p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 33(19P13.3) MUTATED | 35 | 44 | 20 | 29 | 16 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 54 | 55 | 73 | 41 | 38 |
Figure S314. Get High-res Image Gene #66: 'del_19p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00017 (Fisher's exact test), Q value = 0.00097
Table S315. Gene #66: 'del_19p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 33(19P13.3) MUTATED | 20 | 19 | 36 | 34 | 2 | 30 |
| DEL PEAK 33(19P13.3) WILD-TYPE | 54 | 27 | 57 | 32 | 29 | 54 |
Figure S315. Get High-res Image Gene #66: 'del_19p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S316. Gene #67: 'del_22q13.32' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 169 | 140 | 59 | 40 |
| DEL PEAK 34(22Q13.32) MUTATED | 27 | 92 | 49 | 19 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 142 | 48 | 10 | 21 |
Figure S316. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #1: 'CN_CNMF'
P value = 8e-04 (Fisher's exact test), Q value = 0.0038
Table S317. Gene #67: 'del_22q13.32' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 34(22Q13.32) MUTATED | 69 | 64 | 18 | 36 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 69 | 52 | 51 | 49 |
Figure S317. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.046
Table S318. Gene #67: 'del_22q13.32' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 38 | 26 | 18 |
| DEL PEAK 34(22Q13.32) MUTATED | 13 | 24 | 8 | 8 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 29 | 14 | 18 | 10 |
Figure S318. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0412 (Fisher's exact test), Q value = 0.092
Table S319. Gene #67: 'del_22q13.32' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 34(22Q13.32) MUTATED | 59 | 69 | 55 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 57 | 111 | 53 |
Figure S319. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00188 (Fisher's exact test), Q value = 0.0077
Table S320. Gene #67: 'del_22q13.32' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 118 | 112 | 174 |
| DEL PEAK 34(22Q13.32) MUTATED | 58 | 35 | 90 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 60 | 77 | 84 |
Figure S320. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0017 (Fisher's exact test), Q value = 0.0072
Table S321. Gene #67: 'del_22q13.32' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 89 | 99 | 93 | 70 | 54 |
| DEL PEAK 34(22Q13.32) MUTATED | 44 | 55 | 26 | 35 | 26 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 45 | 44 | 67 | 35 | 28 |
Figure S321. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0102 (Fisher's exact test), Q value = 0.032
Table S322. Gene #67: 'del_22q13.32' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 34(22Q13.32) MUTATED | 58 | 18 | 50 | 57 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 40 | 25 | 84 | 62 |
Figure S322. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 9.3e-05
Table S323. Gene #67: 'del_22q13.32' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 34(22Q13.32) MUTATED | 29 | 19 | 50 | 34 | 1 | 50 |
| DEL PEAK 34(22Q13.32) WILD-TYPE | 45 | 27 | 43 | 32 | 30 | 34 |
Figure S323. Get High-res Image Gene #67: 'del_22q13.32' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0338 (Fisher's exact test), Q value = 0.078
Table S324. Gene #68: 'del_xp11.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 35(XP11.3) MUTATED | 11 | 6 | 20 | 22 | 11 | 19 |
| DEL PEAK 35(XP11.3) WILD-TYPE | 63 | 40 | 73 | 44 | 20 | 65 |
Figure S324. Get High-res Image Gene #68: 'del_xp11.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00683 (Fisher's exact test), Q value = 0.024
Table S325. Gene #69: 'del_xq21.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 138 | 116 | 69 | 85 |
| DEL PEAK 36(XQ21.33) MUTATED | 17 | 32 | 12 | 23 |
| DEL PEAK 36(XQ21.33) WILD-TYPE | 121 | 84 | 57 | 62 |
Figure S325. Get High-res Image Gene #69: 'del_xq21.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0222 (Fisher's exact test), Q value = 0.057
Table S326. Gene #69: 'del_xq21.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 116 | 180 | 108 |
| DEL PEAK 36(XQ21.33) MUTATED | 14 | 44 | 25 |
| DEL PEAK 36(XQ21.33) WILD-TYPE | 102 | 136 | 83 |
Figure S326. Get High-res Image Gene #69: 'del_xq21.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0117 (Fisher's exact test), Q value = 0.035
Table S327. Gene #69: 'del_xq21.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 98 | 43 | 134 | 119 |
| DEL PEAK 36(XQ21.33) MUTATED | 13 | 11 | 38 | 18 |
| DEL PEAK 36(XQ21.33) WILD-TYPE | 85 | 32 | 96 | 101 |
Figure S327. Get High-res Image Gene #69: 'del_xq21.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0185 (Fisher's exact test), Q value = 0.05
Table S328. Gene #69: 'del_xq21.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 74 | 46 | 93 | 66 | 31 | 84 |
| DEL PEAK 36(XQ21.33) MUTATED | 7 | 10 | 26 | 16 | 9 | 12 |
| DEL PEAK 36(XQ21.33) WILD-TYPE | 67 | 36 | 67 | 50 | 22 | 72 |
Figure S328. Get High-res Image Gene #69: 'del_xq21.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
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Copy number data file = all_lesions.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/BLCA-TP/15082908/transformed.cor.cli.txt
-
Molecular subtype file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/BLCA-TP/15111049/BLCA-TP.transferedmergedcluster.txt
-
Number of patients = 408
-
Number of significantly focal cnvs = 69
-
Number of molecular subtypes = 10
-
Exclude genes that fewer than K tumors have alterations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.