Correlation between gene mutation status and molecular subtypes
Overview
Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 151 genes and 12 molecular subtypes across 977 patients, 92 significant findings detected with P value < 0.05 and Q value < 0.25.

  • PIK3CA mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'METHLYATION_CNMF',  'RPPA_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • TP53 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'METHLYATION_CNMF',  'RPPA_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • CDH1 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'METHLYATION_CNMF',  'RPPA_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • GATA3 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'METHLYATION_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.

  • MAP3K1 mutation correlated to 'MRNA_CNMF',  'MRNA_CHIERARCHICAL',  'CN_CNMF',  'RPPA_CNMF',  'RPPA_CHIERARCHICAL',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.

  • RUNX1 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

  • CBFB mutation correlated to 'METHLYATION_CNMF',  'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • MAP2K4 mutation correlated to 'MRNA_CHIERARCHICAL',  'METHLYATION_CNMF',  'RPPA_CNMF',  'MRNASEQ_CNMF',  'MRNASEQ_CHIERARCHICAL',  'MIRSEQ_CNMF',  'MIRSEQ_CHIERARCHICAL',  'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • SPEN mutation correlated to 'MIRSEQ_CHIERARCHICAL'.

  • ZFP36L1 mutation correlated to 'CN_CNMF'.

  • DLG1 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.

  • MYB mutation correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.

  • HLA-C mutation correlated to 'MIRSEQ_CHIERARCHICAL'.

  • RAB42 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.

  • ERBB2 mutation correlated to 'METHLYATION_CNMF'.

  • CTCF mutation correlated to 'METHLYATION_CNMF' and 'MIRSEQ_CHIERARCHICAL'.

  • RHBG mutation correlated to 'MRNASEQ_CNMF'.

  • CABYR mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • CCDC82 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • C15ORF39 mutation correlated to 'CN_CNMF',  'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.

  • SDC1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.

  • EXOC4 mutation correlated to 'MRNA_CNMF'.

  • C11ORF49 mutation correlated to 'MRNASEQ_CNMF'.

  • OR8D1 mutation correlated to 'MRNA_CHIERARCHICAL'.

  • LIFR mutation correlated to 'RPPA_CNMF'.

  • SEC14L5 mutation correlated to 'MRNA_CHIERARCHICAL'.

  • FBXW7 mutation correlated to 'METHLYATION_CNMF'.

  • HPS3 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between mutation status of 151 genes and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 92 significant findings detected.

Clinical
Features 		MRNA
CNMF 		MRNA
CHIERARCHICAL 		CN
CNMF 		METHLYATION
CNMF 		RPPA
CNMF 		RPPA
CHIERARCHICAL 		MRNASEQ
CNMF 		MRNASEQ
CHIERARCHICAL 		MIRSEQ
CNMF 		MIRSEQ
CHIERARCHICAL 		MIRSEQ
MATURE
CNMF 		MIRSEQ
MATURE
CHIERARCHICAL
nMutated (%) nWild-Type Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test
PIK3CA 316 (32%) 661 1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		0.00022
(0.00886) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465)
TP53 295 (30%) 682 1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465)
CDH1 106 (11%) 871 0.00034
(0.0134) 		0.00646
(0.16) 		1e-05
(0.000465) 		1e-05
(0.000465) 		0.00732
(0.172) 		0.0129
(0.251) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465) 		1e-05
(0.000465)
GATA3 97 (10%) 880 1e-05
(0.000465) 		1e-05
(0.000465) 		0.0009
(0.0308) 		3e-05
(0.00136) 		0.0205
(0.338) 		0.00077
(0.0272) 		1e-05
(0.000465) 		1e-05
(0.000465) 		0.00177
(0.0563) 		1e-05
(0.000465) 		1e-05
(0.000465) 		0.112
(0.747)
MAP3K1 70 (7%) 907 9e-05
(0.00398) 		0.00016
(0.00674) 		0.00247
(0.0722) 		0.153
(0.78) 		0.00078
(0.0272) 		1e-05
(0.000465) 		0.00045
(0.0166) 		0.00022
(0.00886) 		0.00046
(0.0167) 		0.00105
(0.0352) 		0.111
(0.747) 		0.132
(0.753)
MAP2K4 32 (3%) 945 0.0587
(0.601) 		0.00452
(0.116) 		0.0629
(0.604) 		0.00957
(0.204) 		0.00206
(0.0644) 		0.21
(0.863) 		0.00307
(0.0856) 		0.00377
(0.104) 		0.0117
(0.232) 		0.0004
(0.0151) 		0.0115
(0.232) 		0.0114
(0.232)
CBFB 23 (2%) 954 0.0964
(0.712) 		0.216
(0.868) 		0.068
(0.619) 		0.00011
(0.00475) 		0.124
(0.753) 		0.113
(0.747) 		0.0736
(0.641) 		0.522
(1.00) 		0.0218
(0.35) 		1e-05
(0.000465) 		0.0198
(0.332) 		0.00037
(0.0143)
C15ORF39 9 (1%) 968 0.605
(1.00) 		0.51
(1.00) 		0.00456
(0.116) 		0.0143
(0.262) 		0.519
(1.00) 		0.391
(0.98) 		0.00705
(0.17) 		0.00119
(0.0385) 		0.0231
(0.366) 		0.0291
(0.404) 		0.403
(0.98) 		0.127
(0.753)
RUNX1 29 (3%) 948 0.016
(0.285) 		0.0849
(0.679) 		0.00928
(0.203) 		0.231
(0.884) 		1
(1.00) 		0.331
(0.943) 		0.0647
(0.607) 		0.0118
(0.233) 		0.021
(0.339) 		0.405
(0.98) 		0.31
(0.932) 		0.453
(1.00)
CTCF 17 (2%) 960 0.0591
(0.601) 		0.0439
(0.527) 		0.0174
(0.3) 		0.00946
(0.204) 		0.069
(0.619) 		0.118
(0.747) 		0.0802
(0.665) 		0.369
(0.978) 		0.0708
(0.623) 		0.00235
(0.0707) 		0.841
(1.00) 		0.613
(1.00)
HPS3 9 (1%) 968 0.121
(0.753) 		0.512
(1.00) 		0.237
(0.896) 		0.328
(0.94) 		0.112
(0.747) 		0.152
(0.78) 		0.00514
(0.129) 		0.0042
(0.11) 		0.131
(0.753) 		0.165
(0.794) 		0.0601
(0.604) 		0.575
(1.00)
SPEN 32 (3%) 945 0.664
(1.00) 		0.789
(1.00) 		0.485
(1.00) 		0.503
(1.00) 		0.943
(1.00) 		0.0268
(0.391) 		0.207
(0.863) 		0.118
(0.747) 		0.214
(0.868) 		0.00876
(0.195) 		0.094
(0.704) 		0.658
(1.00)
ZFP36L1 9 (1%) 968 0.404
(0.98) 		0.898
(1.00) 		0.00754
(0.173) 		0.294
(0.931) 		0.0267
(0.391) 		0.0499
(0.558) 		0.254
(0.92) 		0.535
(1.00) 		0.884
(1.00) 		0.775
(1.00) 		0.93
(1.00) 		0.711
(1.00)
DLG1 13 (1%) 964 0.341
(0.956) 		0.318
(0.937) 		0.426
(0.983) 		0.759
(1.00) 		0.895
(1.00) 		0.114
(0.747) 		0.126
(0.753) 		0.185
(0.842) 		0.672
(1.00) 		0.00389
(0.105) 		0.669
(1.00) 		0.805
(1.00)
MYB 12 (1%) 965 0.737
(1.00) 		0.0284
(0.404) 		0.226
(0.884) 		0.353
(0.96) 		1
(1.00) 		0.695
(1.00) 		1
(1.00) 		0.9
(1.00) 		0.0986
(0.716) 		0.124
(0.753) 		0.285
(0.931) 		0.00119
(0.0385)
HLA-C 9 (1%) 968 0.136
(0.756) 		0.849
(1.00) 		0.724
(1.00) 		0.0991
(0.716) 		0.297
(0.931) 		0.571
(1.00) 		0.13
(0.753) 		0.579
(1.00) 		0.0307
(0.416) 		0.0111
(0.231) 		0.0281
(0.404) 		0.589
(1.00)
RAB42 4 (0%) 973 0.408
(0.98) 		0.0705
(0.623) 		0.0406
(0.504) 		0.299
(0.931) 		0.389
(0.98) 		0.118
(0.747) 		0.155
(0.78) 		0.232
(0.884) 		0.01
(0.211)
ERBB2 21 (2%) 956 0.775
(1.00) 		0.572
(1.00) 		0.0637
(0.604) 		0.00271
(0.0767) 		0.499
(1.00) 		0.957
(1.00) 		0.257
(0.921) 		0.126
(0.753) 		0.215
(0.868) 		0.106
(0.747) 		0.32
(0.937) 		0.603
(1.00)
RHBG 4 (0%) 973 0.894
(1.00) 		0.00765
(0.173) 		0.108
(0.747) 		0.523
(1.00) 		0.266
(0.928)
CABYR 6 (1%) 971 0.814
(1.00) 		0.5
(1.00) 		0.136
(0.756) 		0.00666
(0.163) 		0.271
(0.928) 		0.443
(1.00) 		0.873
(1.00) 		0.282
(0.931)
CCDC82 6 (1%) 971 0.459
(1.00) 		0.059
(0.601) 		0.302
(0.931) 		0.0372
(0.485) 		0.72
(1.00) 		0.348
(0.959) 		0.00251
(0.0722) 		0.307
(0.932) 		0.899
(1.00) 		1
(1.00) 		1
(1.00)
SDC1 3 (0%) 974 1
(1.00) 		0.299
(0.931) 		0.00717
(0.171) 		0.495
(1.00) 		1
(1.00)
EXOC4 8 (1%) 969 0.0113
(0.232) 		0.658
(1.00) 		0.671
(1.00) 		0.145
(0.774) 		0.0351
(0.468) 		0.029
(0.404) 		0.808
(1.00) 		0.745
(1.00) 		0.625
(1.00) 		0.418
(0.982)
C11ORF49 5 (1%) 972 0.13
(0.753) 		0.466
(1.00) 		0.00226
(0.0694) 		0.0254
(0.386) 		0.113
(0.747) 		0.0693
(0.619)
OR8D1 5 (1%) 972 0.634
(1.00) 		0.00883
(0.195) 		0.645
(1.00) 		0.865
(1.00) 		0.837
(1.00) 		0.795
(1.00) 		0.337
(0.951) 		0.182
(0.838) 		0.774
(1.00) 		0.593
(1.00)
LIFR 9 (1%) 968 0.321
(0.938) 		0.48
(1.00) 		0.165
(0.794) 		0.888
(1.00) 		0.00754
(0.173) 		0.0165
(0.288) 		1
(1.00) 		0.068
(0.619) 		0.458
(1.00) 		0.871
(1.00) 		0.629
(1.00) 		1
(1.00)
SEC14L5 7 (1%) 970 0.214
(0.868) 		0.00238
(0.0707) 		0.269
(0.928) 		0.514
(1.00) 		0.395
(0.98) 		0.208
(0.863) 		0.0525
(0.581) 		0.0883
(0.684) 		0.115
(0.747) 		0.243
(0.91) 		0.29
(0.931) 		1
(1.00)
FBXW7 15 (2%) 962 0.817
(1.00) 		0.532
(1.00) 		0.156
(0.78) 		0.00408
(0.109) 		0.778
(1.00) 		0.94
(1.00) 		0.23
(0.884) 		0.147
(0.774) 		0.353
(0.96) 		0.0988
(0.716) 		0.0632
(0.604) 		0.898
(1.00)
PTEN 35 (4%) 942 0.309
(0.932) 		0.906
(1.00) 		0.17
(0.804) 		0.423
(0.983) 		0.923
(1.00) 		0.477
(1.00) 		1
(1.00) 		0.573
(1.00) 		0.134
(0.756) 		0.663
(1.00) 		0.65
(1.00) 		0.828
(1.00)
ARID1A 27 (3%) 950 0.302
(0.931) 		0.941
(1.00) 		0.0388
(0.497) 		0.0982
(0.716) 		1
(1.00) 		0.195
(0.854) 		0.347
(0.957) 		0.639
(1.00) 		0.667
(1.00) 		0.403
(0.98) 		0.161
(0.782) 		0.564
(1.00)
MLL3 69 (7%) 908 0.666
(1.00) 		0.155
(0.78) 		0.733
(1.00) 		0.129
(0.753) 		0.595
(1.00) 		0.477
(1.00) 		0.241
(0.905) 		0.448
(1.00) 		0.214
(0.868) 		0.149
(0.775) 		0.41
(0.98) 		0.312
(0.933)
FOXA1 23 (2%) 954 0.369
(0.978) 		0.537
(1.00) 		0.334
(0.945) 		0.0562
(0.589) 		0.895
(1.00) 		0.749
(1.00) 		0.0549
(0.589) 		0.158
(0.782) 		0.0235
(0.368) 		0.0264
(0.391) 		0.185
(0.842) 		0.523
(1.00)
RBMX 14 (1%) 963 0.387
(0.98) 		0.108
(0.747) 		0.0679
(0.619) 		0.108
(0.747) 		0.556
(1.00) 		0.85
(1.00) 		0.149
(0.774) 		0.126
(0.753) 		0.166
(0.798) 		0.659
(1.00) 		0.0465
(0.537) 		1
(1.00)
TBX3 27 (3%) 950 0.579
(1.00) 		0.628
(1.00) 		0.325
(0.94) 		0.127
(0.753) 		0.084
(0.679) 		0.967
(1.00) 		0.0444
(0.529) 		0.133
(0.756) 		0.0589
(0.601) 		0.124
(0.753) 		0.603
(1.00) 		0.721
(1.00)
RB1 19 (2%) 958 0.878
(1.00) 		0.305
(0.932) 		0.157
(0.78) 		0.0306
(0.416) 		0.484
(1.00) 		0.606
(1.00) 		0.0273
(0.396) 		0.26
(0.921) 		0.0566
(0.589) 		0.0264
(0.391) 		0.0929
(0.699) 		0.211
(0.863)
THEM5 11 (1%) 966 0.264
(0.928) 		0.872
(1.00) 		0.0613
(0.604) 		0.599
(1.00) 		0.208
(0.863) 		0.388
(0.98) 		0.608
(1.00) 		0.787
(1.00) 		0.66
(1.00) 		0.465
(1.00) 		0.0401
(0.501) 		0.285
(0.931)
NF1 28 (3%) 949 0.573
(1.00) 		0.804
(1.00) 		0.563
(1.00) 		0.477
(1.00) 		0.742
(1.00) 		0.232
(0.884) 		0.381
(0.98) 		0.417
(0.982) 		0.329
(0.94) 		0.676
(1.00) 		0.942
(1.00) 		0.54
(1.00)
ACTL6B 10 (1%) 967 0.354
(0.96) 		0.29
(0.931) 		0.0285
(0.404) 		0.571
(1.00) 		0.864
(1.00) 		0.196
(0.854) 		0.838
(1.00) 		0.194
(0.854) 		0.739
(1.00) 		0.717
(1.00) 		0.424
(0.983) 		0.713
(1.00)
CDKN1B 10 (1%) 967 0.638
(1.00) 		0.739
(1.00) 		0.0689
(0.619) 		0.142
(0.774) 		0.744
(1.00) 		0.198
(0.854) 		0.1
(0.721) 		0.459
(1.00) 		0.446
(1.00) 		0.169
(0.804) 		0.39
(0.98) 		0.0149
(0.27)
NCOR1 41 (4%) 936 0.741
(1.00) 		0.968
(1.00) 		0.91
(1.00) 		0.916
(1.00) 		0.403
(0.98) 		0.425
(0.983) 		0.755
(1.00) 		0.389
(0.98) 		0.724
(1.00) 		0.108
(0.747) 		0.718
(1.00) 		0.783
(1.00)
SF3B1 16 (2%) 961 0.843
(1.00) 		0.844
(1.00) 		0.535
(1.00) 		0.0906
(0.695) 		0.45
(1.00) 		0.0788
(0.665) 		0.289
(0.931) 		0.356
(0.96) 		0.261
(0.921) 		0.39
(0.98) 		0.351
(0.96) 		0.248
(0.912)
KRAS 6 (1%) 971 0.54
(1.00) 		0.628
(1.00) 		0.324
(0.94) 		0.306
(0.932) 		0.202
(0.856) 		0.513
(1.00) 		0.743
(1.00) 		0.0847
(0.679) 		0.853
(1.00) 		0.958
(1.00) 		0.922
(1.00) 		0.126
(0.753)
AQP12A 6 (1%) 971 0.624
(1.00) 		0.729
(1.00) 		0.345
(0.956) 		0.0232
(0.366) 		0.201
(0.856) 		0.435
(0.993) 		1
(1.00) 		1
(1.00) 		0.945
(1.00) 		0.502
(1.00) 		0.382
(0.98) 		1
(1.00)
TCP11 6 (1%) 971 0.784
(1.00) 		0.511
(1.00) 		0.458
(1.00) 		0.862
(1.00) 		0.607
(1.00) 		0.741
(1.00) 		0.373
(0.978) 		0.945
(1.00) 		0.761
(1.00)
RPGR 19 (2%) 958 0.969
(1.00) 		0.702
(1.00) 		0.96
(1.00) 		0.39
(0.98) 		0.743
(1.00) 		0.294
(0.931) 		0.373
(0.978) 		0.983
(1.00) 		0.227
(0.884) 		0.194
(0.854) 		0.682
(1.00) 		0.477
(1.00)
TBL1XR1 10 (1%) 967 0.157
(0.78) 		0.0807
(0.665) 		0.0134
(0.257) 		0.596
(1.00) 		0.45
(1.00) 		0.153
(0.78) 		0.432
(0.988) 		0.434
(0.992) 		0.389
(0.98) 		0.707
(1.00) 		0.946
(1.00) 		0.178
(0.827)
KDM6A 16 (2%) 961 0.737
(1.00) 		0.344
(0.956) 		0.352
(0.96) 		0.092
(0.695) 		0.637
(1.00) 		0.964
(1.00) 		0.496
(1.00) 		0.329
(0.94) 		0.703
(1.00) 		0.602
(1.00) 		0.736
(1.00) 		0.28
(0.931)
MYH9 18 (2%) 959 0.396
(0.98) 		0.421
(0.982) 		0.365
(0.973) 		0.378
(0.98) 		0.821
(1.00) 		0.0541
(0.587) 		0.661
(1.00) 		0.145
(0.774) 		0.735
(1.00) 		0.402
(0.98) 		0.507
(1.00) 		0.261
(0.921)
FGFR2 11 (1%) 966 0.916
(1.00) 		0.876
(1.00) 		0.327
(0.94) 		0.0918
(0.695) 		1
(1.00) 		0.797
(1.00) 		0.79
(1.00) 		0.431
(0.987) 		0.225
(0.884) 		0.495
(1.00) 		0.605
(1.00) 		0.672
(1.00)
TFE3 7 (1%) 970 0.676
(1.00) 		0.903
(1.00) 		0.74
(1.00) 		0.422
(0.983) 		1
(1.00) 		0.94
(1.00) 		0.787
(1.00) 		0.65
(1.00) 		0.756
(1.00) 		0.427
(0.983) 		0.857
(1.00) 		0.301
(0.931)
ZMYM3 14 (1%) 963 0.495
(1.00) 		0.44
(0.998) 		0.838
(1.00) 		0.314
(0.933) 		0.126
(0.753) 		0.656
(1.00) 		0.161
(0.782) 		0.568
(1.00) 		0.516
(1.00) 		0.906
(1.00) 		0.229
(0.884) 		0.856
(1.00)
FRMPD2 12 (1%) 965 0.819
(1.00) 		1
(1.00) 		0.372
(0.978) 		0.767
(1.00) 		0.467
(1.00) 		0.935
(1.00) 		0.795
(1.00) 		0.0615
(0.604) 		0.424
(0.983) 		0.673
(1.00) 		0.188
(0.847) 		0.753
(1.00)
GPS2 11 (1%) 966 0.014
(0.261) 		0.0493
(0.558) 		0.061
(0.604) 		0.311
(0.932) 		0.329
(0.94) 		0.66
(1.00) 		0.392
(0.98) 		0.0417
(0.504) 		0.137
(0.756) 		0.31
(0.932) 		0.478
(1.00) 		0.418
(0.982)
DOCK11 20 (2%) 957 0.666
(1.00) 		0.448
(1.00) 		0.314
(0.933) 		0.803
(1.00) 		0.402
(0.98) 		0.269
(0.928) 		0.062
(0.604) 		0.0251
(0.386) 		0.0914
(0.695) 		0.0457
(0.535) 		0.0382
(0.495) 		0.116
(0.747)
HRNR 31 (3%) 946 0.988
(1.00) 		0.783
(1.00) 		0.353
(0.96) 		0.946
(1.00) 		0.624
(1.00) 		0.57
(1.00) 		0.491
(1.00) 		0.679
(1.00) 		0.597
(1.00) 		0.194
(0.854) 		0.148
(0.774) 		0.784
(1.00)
CASZ1 14 (1%) 963 0.936
(1.00) 		0.854
(1.00) 		0.903
(1.00) 		0.867
(1.00) 		0.111
(0.747) 		0.934
(1.00) 		0.823
(1.00) 		0.733
(1.00) 		0.521
(1.00) 		0.733
(1.00) 		0.429
(0.984) 		0.326
(0.94)
CDC42EP1 5 (1%) 972 0.521
(1.00) 		0.463
(1.00) 		0.384
(0.98) 		0.424
(0.983) 		0.835
(1.00) 		0.472
(1.00) 		0.844
(1.00) 		0.557
(1.00) 		0.729
(1.00) 		0.305
(0.932)
C1QTNF5 7 (1%) 970 0.648
(1.00) 		0.2
(0.856) 		0.283
(0.931) 		1
(1.00) 		0.511
(1.00) 		0.877
(1.00) 		0.338
(0.951) 		0.695
(1.00) 		0.084
(0.679) 		0.0137
(0.259) 		0.0796
(0.665)
TGS1 13 (1%) 964 0.634
(1.00) 		0.667
(1.00) 		0.42
(0.982) 		0.292
(0.931) 		0.112
(0.747) 		0.555
(1.00) 		1
(1.00) 		0.246
(0.912) 		0.271
(0.928) 		0.457
(1.00) 		0.248
(0.912) 		0.356
(0.96)
USP36 8 (1%) 969 0.837
(1.00) 		0.182
(0.838) 		0.968
(1.00) 		0.823
(1.00) 		0.712
(1.00) 		0.744
(1.00) 		0.457
(1.00) 		0.0769
(0.661) 		0.675
(1.00) 		0.347
(0.957)
ASB10 8 (1%) 969 0.944
(1.00) 		0.0643
(0.607) 		0.967
(1.00) 		0.708
(1.00) 		0.457
(1.00) 		0.58
(1.00) 		0.485
(1.00) 		0.267
(0.928) 		0.902
(1.00) 		1
(1.00)
EIF4A2 9 (1%) 968 0.23
(0.884) 		1
(1.00) 		0.881
(1.00) 		0.565
(1.00) 		1
(1.00) 		0.369
(0.978) 		0.227
(0.884) 		0.084
(0.679) 		0.26
(0.921) 		0.891
(1.00) 		0.372
(0.978) 		0.282
(0.931)
DNAH12 18 (2%) 959 1
(1.00) 		0.732
(1.00) 		0.865
(1.00) 		0.748
(1.00) 		0.451
(1.00) 		0.898
(1.00) 		1
(1.00) 		0.605
(1.00) 		0.246
(0.912) 		0.727
(1.00) 		0.16
(0.782) 		0.228
(0.884)
ZNF362 5 (1%) 972 0.88
(1.00) 		0.872
(1.00) 		0.0916
(0.695) 		0.155
(0.78) 		0.659
(1.00) 		0.408
(0.98) 		0.91
(1.00) 		0.083
(0.679) 		0.414
(0.982)
FXYD5 5 (1%) 972 0.568
(1.00) 		0.786
(1.00) 		0.451
(1.00) 		0.522
(1.00) 		0.883
(1.00) 		0.0874
(0.681) 		0.122
(0.753) 		0.685
(1.00) 		0.512
(1.00)
BCORL1 15 (2%) 962 0.151
(0.78) 		0.834
(1.00) 		0.66
(1.00) 		0.736
(1.00) 		0.29
(0.931) 		0.0292
(0.404) 		0.116
(0.747) 		0.819
(1.00) 		0.559
(1.00) 		0.879
(1.00) 		0.876
(1.00) 		0.665
(1.00)
PTHLH 7 (1%) 970 0.229
(0.884) 		0.897
(1.00) 		0.039
(0.497) 		0.0205
(0.338) 		0.688
(1.00) 		0.576
(1.00) 		0.136
(0.756) 		0.654
(1.00) 		1
(1.00) 		0.194
(0.854)
PIK3R1 15 (2%) 962 0.148
(0.774) 		0.185
(0.842) 		0.414
(0.982) 		0.0673
(0.619) 		0.63
(1.00) 		0.0495
(0.558) 		0.101
(0.722) 		0.159
(0.782) 		0.132
(0.753) 		0.395
(0.98) 		0.119
(0.747) 		0.667
(1.00)
ZNF687 11 (1%) 966 0.344
(0.956) 		0.129
(0.753) 		0.224
(0.884) 		0.119
(0.747) 		0.115
(0.747) 		0.305
(0.932) 		0.198
(0.854) 		0.25
(0.913) 		0.198
(0.854) 		0.0181
(0.31) 		0.874
(1.00) 		0.597
(1.00)
GPRIN2 11 (1%) 966 0.604
(1.00) 		0.624
(1.00) 		0.981
(1.00) 		0.706
(1.00) 		0.876
(1.00) 		0.145
(0.774) 		0.468
(1.00) 		0.421
(0.982) 		0.372
(0.978) 		0.0633
(0.604) 		0.402
(0.98) 		0.665
(1.00)
ANKRD12 18 (2%) 959 0.277
(0.931) 		0.134
(0.756) 		0.626
(1.00) 		0.858
(1.00) 		0.386
(0.98) 		0.0674
(0.619) 		0.409
(0.98) 		0.0631
(0.604) 		0.207
(0.863) 		0.948
(1.00) 		0.202
(0.856) 		0.714
(1.00)
PAX2 4 (0%) 973 0.945
(1.00) 		0.334
(0.945) 		0.3
(0.931) 		0.401
(0.98) 		0.0564
(0.589) 		0.317
(0.934) 		0.286
(0.931) 		0.776
(1.00) 		0.483
(1.00)
KCNN3 9 (1%) 968 0.143
(0.774) 		0.51
(1.00) 		0.25
(0.913) 		0.137
(0.756) 		0.27
(0.928) 		0.767
(1.00) 		0.288
(0.931) 		0.401
(0.98) 		0.302
(0.931) 		0.71
(1.00) 		0.584
(1.00) 		0.414
(0.982)
ICOSLG 5 (1%) 972 0.767
(1.00) 		0.129
(0.753) 		0.0409
(0.504) 		0.289
(0.931) 		0.599
(1.00) 		0.969
(1.00) 		0.77
(1.00) 		0.472
(1.00)
MR1 7 (1%) 970 0.211
(0.863) 		0.704
(1.00) 		0.924
(1.00) 		0.056
(0.589) 		1
(1.00) 		0.966
(1.00) 		0.27
(0.928) 		0.362
(0.968) 		0.574
(1.00) 		0.219
(0.876)
ZBTB7C 5 (1%) 972 0.494
(1.00) 		0.788
(1.00) 		0.495
(1.00) 		0.678
(1.00) 		0.687
(1.00) 		0.922
(1.00)
AKT2 5 (1%) 972 0.144
(0.774) 		1
(1.00) 		0.68
(1.00) 		0.456
(1.00) 		0.598
(1.00) 		0.112
(0.747) 		0.769
(1.00) 		0.309
(0.932) 		0.677
(1.00) 		0.443
(1.00)
TARBP2 6 (1%) 971 0.662
(1.00) 		0.958
(1.00) 		0.102
(0.728) 		0.683
(1.00) 		0.167
(0.798) 		0.597
(1.00) 		0.138
(0.756) 		0.466
(1.00) 		0.615
(1.00) 		0.0654
(0.611) 		0.498
(1.00) 		0.768
(1.00)
RIBC1 4 (0%) 973 0.591
(1.00) 		0.383
(0.98) 		0.758
(1.00) 		0.489
(1.00) 		0.53
(1.00) 		0.608
(1.00) 		0.447
(1.00) 		0.329
(0.94)
PSIP1 8 (1%) 969 0.687
(1.00) 		0.719
(1.00) 		0.569
(1.00) 		0.767
(1.00) 		0.689
(1.00) 		0.967
(1.00) 		0.36
(0.966) 		0.936
(1.00) 		0.21
(0.863) 		0.454
(1.00) 		0.858
(1.00) 		0.13
(0.753)
CEP57 6 (1%) 971 0.373
(0.978) 		0.279
(0.931) 		0.301
(0.931) 		0.188
(0.847) 		0.651
(1.00) 		0.849
(1.00) 		0.0703
(0.623) 		0.984
(1.00) 		0.0808
(0.665) 		0.0397
(0.499)
ANKRD20A4 7 (1%) 970 0.191
(0.853) 		0.0963
(0.712) 		0.713
(1.00) 		0.516
(1.00) 		0.78
(1.00) 		1
(1.00) 		0.234
(0.884) 		0.332
(0.943) 		0.882
(1.00) 		0.967
(1.00) 		0.477
(1.00) 		0.036
(0.473)
HIST1H3B 11 (1%) 966 0.555
(1.00) 		0.96
(1.00) 		0.641
(1.00) 		0.785
(1.00) 		0.628
(1.00) 		0.707
(1.00) 		1
(1.00) 		0.169
(0.804) 		0.71
(1.00) 		0.178
(0.827) 		0.84
(1.00) 		0.663
(1.00)
MED23 14 (1%) 963 0.0973
(0.714) 		0.282
(0.931) 		0.355
(0.96) 		0.447
(1.00) 		0.157
(0.78) 		0.221
(0.881) 		0.0488
(0.558) 		0.0743
(0.645) 		0.356
(0.96) 		0.389
(0.98) 		0.28
(0.931) 		0.416
(0.982)
MUC6 14 (1%) 963 0.0208
(0.339) 		0.613
(1.00) 		0.506
(1.00) 		0.77
(1.00) 		0.365
(0.973) 		0.941
(1.00) 		0.0618
(0.604) 		0.204
(0.859) 		0.621
(1.00) 		0.115
(0.747) 		0.286
(0.931) 		0.0503
(0.56)
ANGPT4 10 (1%) 967 0.203
(0.859) 		1
(1.00) 		0.402
(0.98) 		0.257
(0.921) 		0.642
(1.00) 		0.941
(1.00) 		0.045
(0.531) 		0.0451
(0.531) 		0.163
(0.792) 		0.606
(1.00) 		0.96
(1.00) 		0.416
(0.982)
PCNXL2 21 (2%) 956 0.953
(1.00) 		0.938
(1.00) 		0.729
(1.00) 		0.848
(1.00) 		0.482
(1.00) 		0.58
(1.00) 		0.404
(0.98) 		0.725
(1.00) 		0.77
(1.00) 		0.586
(1.00) 		0.972
(1.00) 		0.824
(1.00)
SLC35B2 7 (1%) 970 1
(1.00) 		0.248
(0.912) 		0.801
(1.00) 		0.559
(1.00) 		0.849
(1.00) 		0.784
(1.00) 		0.885
(1.00) 		0.622
(1.00) 		0.908
(1.00) 		0.929
(1.00) 		0.855
(1.00)
MKL1 5 (1%) 972 0.9
(1.00) 		0.692
(1.00) 		0.428
(0.983) 		0.78
(1.00) 		0.346
(0.957) 		0.713
(1.00) 		0.119
(0.749) 		0.818
(1.00) 		0.39
(0.98)
NBPF9 5 (1%) 972 0.615
(1.00) 		0.625
(1.00) 		0.805
(1.00) 		0.864
(1.00) 		0.641
(1.00) 		0.6
(1.00) 		0.155
(0.78) 		0.145
(0.774) 		0.3
(0.931)
PRICKLE3 11 (1%) 966 0.259
(0.921) 		0.0267
(0.391) 		0.684
(1.00) 		0.743
(1.00) 		0.511
(1.00) 		0.549
(1.00) 		0.197
(0.854) 		0.206
(0.863) 		0.668
(1.00) 		0.402
(0.98) 		0.606
(1.00) 		0.671
(1.00)
CXCR3 6 (1%) 971 0.604
(1.00) 		0.79
(1.00) 		0.156
(0.78) 		0.539
(1.00) 		1
(1.00) 		0.887
(1.00) 		0.653
(1.00) 		0.439
(0.998) 		0.709
(1.00) 		0.899
(1.00) 		0.503
(1.00) 		0.522
(1.00)
TPP2 8 (1%) 969 0.0857
(0.679) 		0.945
(1.00) 		0.638
(1.00) 		0.26
(0.921) 		0.362
(0.968) 		0.915
(1.00) 		0.531
(1.00) 		0.879
(1.00) 		0.875
(1.00) 		0.595
(1.00)
CASP8 12 (1%) 965 0.463
(1.00) 		0.392
(0.98) 		0.26
(0.921) 		0.288
(0.931) 		0.529
(1.00) 		0.661
(1.00) 		1
(1.00) 		0.755
(1.00) 		0.449
(1.00) 		0.475
(1.00) 		0.176
(0.822) 		1
(1.00)
TNRC6B 18 (2%) 959 0.519
(1.00) 		0.157
(0.78) 		0.576
(1.00) 		0.142
(0.774) 		0.508
(1.00) 		0.481
(1.00) 		0.734
(1.00) 		0.327
(0.94) 		0.951
(1.00) 		0.202
(0.856) 		0.654
(1.00) 		0.369
(0.978)
OXCT2 4 (0%) 973 0.451
(1.00) 		0.54
(1.00) 		0.896
(1.00) 		1
(1.00) 		0.502
(1.00) 		1
(1.00) 		0.469
(1.00)
IRS4 11 (1%) 966 0.144
(0.774) 		0.784
(1.00) 		0.223
(0.882) 		0.757
(1.00) 		0.381
(0.98) 		0.845
(1.00) 		0.216
(0.868) 		0.473
(1.00) 		1
(1.00) 		0.173
(0.816) 		0.948
(1.00) 		0.823
(1.00)
MLL4 13 (1%) 964 0.397
(0.98) 		0.509
(1.00) 		0.791
(1.00) 		0.222
(0.881) 		0.115
(0.747) 		0.547
(1.00) 		0.533
(1.00) 		0.303
(0.931) 		0.324
(0.94) 		0.0911
(0.695) 		0.351
(0.96) 		0.3
(0.931)
RHOA 6 (1%) 971 0.904
(1.00) 		0.587
(1.00) 		0.778
(1.00) 		0.968
(1.00) 		0.112
(0.747) 		0.606
(1.00) 		0.412
(0.982) 		0.259
(0.921) 		1
(1.00) 		0.794
(1.00)
ATHL1 10 (1%) 967 0.87
(1.00) 		0.319
(0.937) 		0.0851
(0.679) 		0.147
(0.774) 		1
(1.00) 		0.8
(1.00) 		0.333
(0.945) 		0.145
(0.774) 		0.186
(0.842) 		0.053
(0.581) 		0.343
(0.956) 		0.686
(1.00)
LILRA6 6 (1%) 971 0.658
(1.00) 		0.219
(0.876) 		0.817
(1.00) 		0.211
(0.863) 		1
(1.00) 		0.863
(1.00) 		0.677
(1.00) 		0.371
(0.978) 		0.96
(1.00)
MLH1 6 (1%) 971 0.799
(1.00) 		0.732
(1.00) 		0.902
(1.00) 		0.785
(1.00) 		0.345
(0.956) 		0.879
(1.00) 		0.816
(1.00) 		0.544
(1.00) 		0.949
(1.00) 		0.822
(1.00)
NUP93 4 (0%) 973 0.0157
(0.281) 		0.467
(1.00) 		0.421
(0.982) 		0.475
(1.00) 		0.493
(1.00) 		0.502
(1.00)
ALDH1L1 9 (1%) 968 0.646
(1.00) 		0.92
(1.00) 		0.251
(0.915) 		0.177
(0.827) 		0.692
(1.00) 		0.258
(0.921) 		0.125
(0.753) 		0.288
(0.931) 		0.283
(0.931) 		0.279
(0.931) 		0.899
(1.00) 		0.821
(1.00)
TMEM120B 5 (1%) 972 0.257
(0.921) 		0.247
(0.912) 		0.868
(1.00) 		0.977
(1.00) 		0.222
(0.881) 		0.863
(1.00) 		0.516
(1.00) 		0.59
(1.00) 		1
(1.00) 		1
(1.00)
LRIG2 7 (1%) 970 0.564
(1.00) 		0.0308
(0.416) 		0.246
(0.912) 		0.207
(0.863) 		0.211
(0.863) 		0.721
(1.00) 		0.461
(1.00) 		0.886
(1.00) 		0.623
(1.00) 		0.608
(1.00) 		0.856
(1.00) 		1
(1.00)
CCDC78 5 (1%) 972 0.613
(1.00) 		0.708
(1.00) 		0.715
(1.00) 		0.497
(1.00) 		0.389
(0.98) 		0.875
(1.00) 		0.848
(1.00) 		0.591
(1.00)
GAL3ST1 5 (1%) 972 0.758
(1.00) 		0.715
(1.00) 		1
(1.00) 		0.864
(1.00) 		0.306
(0.932) 		0.449
(1.00) 		0.262
(0.923) 		0.589
(1.00)
FAM20C 4 (0%) 973 0.594
(1.00) 		0.419
(0.982) 		0.55
(1.00) 		0.127
(0.753) 		0.63
(1.00) 		0.498
(1.00) 		0.769
(1.00)
RCC1 3 (0%) 974 0.715
(1.00) 		0.112
(0.747) 		0.17
(0.804) 		0.299
(0.931) 		0.453
(1.00) 		1
(1.00) 		0.946
(1.00)
CHD4 19 (2%) 958 0.233
(0.884) 		0.355
(0.96) 		0.848
(1.00) 		0.684
(1.00) 		0.197
(0.854) 		0.396
(0.98) 		0.554
(1.00) 		0.268
(0.928) 		0.3
(0.931) 		0.439
(0.998) 		0.749
(1.00) 		0.31
(0.932)
STAG2 13 (1%) 964 0.284
(0.931) 		0.213
(0.868) 		0.191
(0.853) 		0.481
(1.00) 		0.877
(1.00) 		0.226
(0.884) 		0.334
(0.945) 		0.864
(1.00) 		0.253
(0.919) 		0.79
(1.00) 		0.902
(1.00) 		0.685
(1.00)
HIST1H2BC 6 (1%) 971 0.374
(0.978) 		0.0465
(0.537) 		0.709
(1.00) 		0.295
(0.931) 		0.392
(0.98) 		0.642
(1.00) 		0.0875
(0.681) 		0.847
(1.00) 		0.742
(1.00) 		0.857
(1.00) 		0.948
(1.00) 		0.823
(1.00)
BPHL 5 (1%) 972 0.474
(1.00) 		0.467
(1.00) 		0.585
(1.00) 		0.688
(1.00) 		0.402
(0.98) 		0.713
(1.00) 		0.318
(0.937) 		0.182
(0.838) 		0.569
(1.00)
ATP2A1 11 (1%) 966 1
(1.00) 		0.678
(1.00) 		0.538
(1.00) 		0.655
(1.00) 		1
(1.00) 		0.769
(1.00) 		1
(1.00) 		0.996
(1.00) 		0.979
(1.00) 		0.684
(1.00)
LRRC37A3 10 (1%) 967 0.036
(0.473) 		0.551
(1.00) 		0.79
(1.00) 		0.853
(1.00) 		0.3
(0.931) 		0.668
(1.00) 		1
(1.00) 		0.615
(1.00) 		0.646
(1.00) 		0.303
(0.931) 		0.356
(0.96) 		0.667
(1.00)
EPDR1 5 (1%) 972 0.314
(0.933) 		0.82
(1.00) 		0.755
(1.00) 		0.555
(1.00) 		0.449
(1.00) 		0.715
(1.00) 		0.494
(1.00) 		0.775
(1.00) 		0.58
(1.00)
SARM1 6 (1%) 971 0.56
(1.00) 		0.116
(0.747) 		0.747
(1.00) 		0.517
(1.00) 		0.13
(0.753) 		0.0252
(0.386) 		0.0198
(0.332) 		0.78
(1.00) 		0.33
(0.94) 		0.54
(1.00) 		0.303
(0.931)
SP3 7 (1%) 970 0.88
(1.00) 		0.552
(1.00) 		0.557
(1.00) 		0.865
(1.00) 		0.878
(1.00) 		0.442
(1.00) 		0.395
(0.98) 		0.411
(0.98) 		0.316
(0.934) 		1
(1.00)
ACTG1 8 (1%) 969 0.288
(0.931) 		0.395
(0.98) 		0.891
(1.00) 		0.159
(0.782) 		0.709
(1.00) 		0.425
(0.983) 		0.294
(0.931) 		0.64
(1.00) 		0.146
(0.774) 		1
(1.00)
ANXA11 3 (0%) 974 0.668
(1.00) 		0.493
(1.00) 		0.403
(0.98) 		0.0628
(0.604) 		0.632
(1.00) 		0.592
(1.00) 		0.858
(1.00) 		0.183
(0.839) 		0.271
(0.928)
GYLTL1B 4 (0%) 973 0.419
(0.982) 		0.72
(1.00) 		1
(1.00) 		0.69
(1.00) 		0.358
(0.962) 		0.659
(1.00) 		0.447
(1.00) 		0.315
(0.934) 		0.409
(0.98)
ANGPTL6 3 (0%) 974 0.751
(1.00) 		0.769
(1.00) 		0.617
(1.00)
PFKP 7 (1%) 970 0.407
(0.98) 		0.0135
(0.257) 		0.233
(0.884) 		0.056
(0.589) 		0.28
(0.931) 		0.569
(1.00) 		0.461
(1.00) 		0.277
(0.931) 		0.117
(0.747) 		0.21
(0.863)
SPTAN1 11 (1%) 966 0.788
(1.00) 		0.64
(1.00) 		0.32
(0.937) 		0.787
(1.00) 		0.111
(0.747) 		0.153
(0.78) 		0.056
(0.589) 		0.498
(1.00) 		0.706
(1.00) 		0.231
(0.884) 		0.344
(0.956) 		0.137
(0.756)
TTPAL 4 (0%) 973 0.24
(0.903) 		0.302
(0.931) 		0.159
(0.782) 		0.522
(1.00) 		0.781
(1.00) 		0.0497
(0.558) 		0.396
(0.98) 		0.522
(1.00) 		0.0869
(0.681)
HCFC2 10 (1%) 967 0.031
(0.416) 		0.554
(1.00) 		0.136
(0.756) 		0.923
(1.00) 		0.0143
(0.262) 		0.246
(0.912) 		0.739
(1.00) 		0.985
(1.00) 		0.61
(1.00) 		0.477
(1.00)
OR6C76 7 (1%) 970 0.292
(0.931) 		0.342
(0.956) 		0.399
(0.98) 		0.939
(1.00) 		0.642
(1.00) 		0.485
(1.00) 		0.877
(1.00) 		0.622
(1.00) 		0.88
(1.00) 		0.808
(1.00) 		0.156
(0.78) 		0.254
(0.92)
ACOT2 5 (1%) 972 0.184
(0.842) 		0.342
(0.956) 		0.428
(0.983) 		0.479
(1.00) 		0.496
(1.00) 		0.74
(1.00) 		0.0162
(0.285) 		0.636
(1.00)
KIAA0430 15 (2%) 962 0.671
(1.00) 		0.75
(1.00) 		0.13
(0.753) 		0.109
(0.747) 		0.269
(0.928) 		0.72
(1.00) 		0.835
(1.00) 		0.862
(1.00) 		1
(1.00) 		0.65
(1.00) 		0.161
(0.782) 		0.569
(1.00)
GTF2IRD2 8 (1%) 969 0.57
(1.00) 		0.959
(1.00) 		0.0967
(0.712) 		0.407
(0.98) 		0.383
(0.98) 		0.977
(1.00) 		0.41
(0.98) 		0.78
(1.00) 		0.471
(1.00) 		0.0417
(0.504) 		0.128
(0.753) 		0.439
(0.998)
JAK1 11 (1%) 966 0.499
(1.00) 		0.479
(1.00) 		0.673
(1.00) 		0.414
(0.982) 		1
(1.00) 		0.732
(1.00) 		0.0412
(0.504) 		0.193
(0.854) 		0.23
(0.884) 		0.123
(0.753) 		0.215
(0.868) 		0.17
(0.804)
FGFR3 4 (0%) 973 0.0759
(0.655) 		0.924
(1.00) 		0.823
(1.00) 		0.415
(0.982) 		0.396
(0.98) 		0.566
(1.00) 		0.25
(0.913)
SHANK2 15 (2%) 962 0.105
(0.746) 		0.197
(0.854) 		0.609
(1.00) 		0.559
(1.00) 		0.0532
(0.581) 		0.343
(0.956) 		0.474
(1.00) 		0.288
(0.931) 		0.411
(0.98) 		0.314
(0.933) 		0.0788
(0.665) 		0.185
(0.842)
TRMT2A 7 (1%) 970 0.953
(1.00) 		0.92
(1.00) 		0.769
(1.00) 		0.782
(1.00) 		0.393
(0.98) 		1
(1.00) 		0.523
(1.00) 		0.572
(1.00) 		0.844
(1.00) 		0.763
(1.00) 		0.552
(1.00) 		0.189
(0.851)
CCNL2 7 (1%) 970 0.864
(1.00) 		0.855
(1.00) 		1
(1.00) 		0.939
(1.00) 		0.525
(1.00) 		0.284
(0.931) 		0.539
(1.00) 		0.174
(0.819) 		0.948
(1.00) 		0.824
(1.00)
CLEC18B 6 (1%) 971 0.565
(1.00) 		1
(1.00) 		0.647
(1.00) 		0.509
(1.00) 		0.298
(0.931) 		0.94
(1.00) 		0.567
(1.00) 		0.752
(1.00) 		0.899
(1.00) 		0.392
(0.98) 		0.857
(1.00) 		0.301
(0.931)
RUFY1 6 (1%) 971 0.382
(0.98) 		0.731
(1.00) 		0.316
(0.934) 		0.526
(1.00) 		0.651
(1.00) 		0.241
(0.905) 		0.85
(1.00) 		0.133
(0.756) 		0.899
(1.00) 		0.409
(0.98)
GIPC3 4 (0%) 973 0.831
(1.00) 		0.5
(1.00) 		0.405
(0.98) 		0.401
(0.98) 		0.0803
(0.665) 		0.316
(0.934) 		0.648
(1.00) 		0.0779
(0.662) 		0.495
(1.00)
OR2T35 4 (0%) 973 1
(1.00) 		0.0951
(0.709) 		0.894
(1.00) 		0.821
(1.00) 		0.717
(1.00) 		0.259
(0.921) 		0.533
(1.00)
PPIL2 6 (1%) 971 0.427
(0.983) 		0.825
(1.00) 		1
(1.00) 		0.409
(0.98) 		0.392
(0.98) 		1
(1.00) 		0.191
(0.853) 		0.0395
(0.499)
NPAS4 9 (1%) 968 0.672
(1.00) 		0.148
(0.774) 		0.216
(0.868) 		0.36
(0.966) 		0.837
(1.00) 		0.875
(1.00) 		0.327
(0.94) 		0.232
(0.884) 		0.385
(0.98) 		0.149
(0.774) 		0.243
(0.91) 		0.823
(1.00)
SHISA4 5 (1%) 972 0.0873
(0.681) 		0.729
(1.00) 		0.0777
(0.662) 		0.125
(0.753) 		0.497
(1.00) 		0.269
(0.928) 		0.874
(1.00) 		1
(1.00)
MLL 17 (2%) 960 0.65
(1.00) 		0.645
(1.00) 		0.0596
(0.603) 		0.0858
(0.679) 		0.688
(1.00) 		0.272
(0.93) 		0.25
(0.913) 		0.356
(0.96) 		0.83
(1.00) 		0.196
(0.854) 		0.279
(0.931) 		0.0691
(0.619)
ACVR1B 7 (1%) 970 0.89
(1.00) 		1
(1.00) 		0.949
(1.00) 		0.781
(1.00) 		0.558
(1.00) 		0.201
(0.856) 		0.198
(0.854) 		0.478
(1.00) 		0.373
(0.978) 		0.511
(1.00) 		0.537
(1.00) 		0.303
(0.931)
GPR158 3 (0%) 974 1
(1.00) 		0.3
(0.931) 		0.456
(1.00) 		0.325
(0.94) 		0.306
(0.932)
ARHGEF15 9 (1%) 968 0.464
(1.00) 		0.199
(0.855) 		0.34
(0.956) 		1
(1.00) 		0.893
(1.00) 		0.738
(1.00) 		0.328
(0.94) 		0.626
(1.00) 		0.861
(1.00) 		0.564
(1.00) 		0.856
(1.00) 		0.3
(0.931)
ZNF397 7 (1%) 970 0.0714
(0.625) 		0.85
(1.00) 		0.167
(0.798) 		0.672
(1.00) 		1
(1.00) 		0.642
(1.00) 		0.723
(1.00) 		0.652
(1.00) 		0.608
(1.00) 		0.67
(1.00)
COL9A2 3 (0%) 974 0.309
(0.932) 		0.136
(0.756) 		0.296
(0.931) 		0.476
(1.00)
TXNDC2 4 (0%) 973 0.456
(1.00) 		0.69
(1.00) 		0.118
(0.747) 		0.265
(0.928) 		0.234
(0.884) 		0.644
(1.00)
CD244 3 (0%) 974 0.355
(0.96) 		0.11
(0.747) 		0.28
(0.931) 		1
(1.00) 		1
(1.00)
'PIK3CA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S1.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PIK3CA MUTATED 7 13 23 8 61 23 8 21
PIK3CA WILD-TYPE 14 25 91 89 47 50 11 18

Figure S1.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'PIK3CA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S2.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PIK3CA MUTATED 19 70 39 5 31
PIK3CA WILD-TYPE 77 82 77 84 25

Figure S2.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S3.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PIK3CA MUTATED 61 147 48 49 9
PIK3CA WILD-TYPE 186 216 38 182 27

Figure S3.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PIK3CA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S4.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PIK3CA MUTATED 33 39 78 33 6 19
PIK3CA WILD-TYPE 95 57 78 74 103 33

Figure S4.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PIK3CA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00022 (Fisher's exact test), Q value = 0.0089

Table S5.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PIK3CA MUTATED 27 49 46
PIK3CA WILD-TYPE 118 82 72

Figure S5.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'PIK3CA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S6.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PIK3CA MUTATED 30 24 12 23 27 6
PIK3CA WILD-TYPE 29 24 78 30 86 25

Figure S6.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S7.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PIK3CA MUTATED 187 44 85
PIK3CA WILD-TYPE 318 235 105

Figure S7.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S8.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PIK3CA MUTATED 79 55 34 125 7 16
PIK3CA WILD-TYPE 184 96 45 136 161 36

Figure S8.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S9.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PIK3CA MUTATED 43 70 97 104
PIK3CA WILD-TYPE 229 107 136 172

Figure S9.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S10.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PIK3CA MUTATED 99 32 89 73 15 6
PIK3CA WILD-TYPE 176 104 117 61 72 114

Figure S10.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S11.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
PIK3CA MUTATED 57 14 27 34 50
PIK3CA WILD-TYPE 121 106 39 58 62

Figure S11.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S12.  Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
PIK3CA MUTATED 52 75 55
PIK3CA WILD-TYPE 227 106 53

Figure S12.  Get High-res Image Gene #1: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S13.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TP53 MUTATED 7 6 18 73 6 41 7 6
TP53 WILD-TYPE 14 32 96 24 102 32 12 33

Figure S13.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'TP53 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S14.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TP53 MUTATED 12 17 65 68 2
TP53 WILD-TYPE 84 135 51 21 54

Figure S14.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S15.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TP53 MUTATED 59 52 8 165 8
TP53 WILD-TYPE 188 311 78 66 28

Figure S15.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S16.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TP53 MUTATED 30 28 9 32 82 9
TP53 WILD-TYPE 98 68 147 75 27 43

Figure S16.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S17.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TP53 MUTATED 93 11 33
TP53 WILD-TYPE 52 120 85

Figure S17.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S18.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TP53 MUTATED 4 7 67 10 31 18
TP53 WILD-TYPE 55 41 23 43 82 13

Figure S18.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S19.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TP53 MUTATED 77 200 17
TP53 WILD-TYPE 428 79 173

Figure S19.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S20.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TP53 MUTATED 25 64 3 37 125 40
TP53 WILD-TYPE 238 87 76 224 43 12

Figure S20.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S21.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TP53 MUTATED 171 27 26 64
TP53 WILD-TYPE 101 150 207 212

Figure S21.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S22.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TP53 MUTATED 71 85 23 15 4 90
TP53 WILD-TYPE 204 51 183 119 83 30

Figure S22.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S23.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TP53 MUTATED 30 90 9 18 24
TP53 WILD-TYPE 148 30 57 74 88

Figure S23.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S24.  Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TP53 MUTATED 120 35 16
TP53 WILD-TYPE 159 146 92

Figure S24.  Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CDH1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00034 (Fisher's exact test), Q value = 0.013

Table S25.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CDH1 MUTATED 0 6 2 1 10 6 1 7
CDH1 WILD-TYPE 21 32 112 96 98 67 18 32

Figure S25.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'CDH1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00646 (Fisher's exact test), Q value = 0.16

Table S26.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CDH1 MUTATED 4 19 7 1 2
CDH1 WILD-TYPE 92 133 109 88 54

Figure S26.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CDH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S27.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CDH1 MUTATED 13 59 23 4 5
CDH1 WILD-TYPE 234 304 63 227 31

Figure S27.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CDH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S28.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CDH1 MUTATED 3 19 32 21 0 7
CDH1 WILD-TYPE 125 77 124 86 109 45

Figure S28.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CDH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00732 (Fisher's exact test), Q value = 0.17

Table S29.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CDH1 MUTATED 5 4 14
CDH1 WILD-TYPE 140 127 104

Figure S29.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'CDH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0129 (Fisher's exact test), Q value = 0.25

Table S30.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CDH1 MUTATED 1 7 1 5 7 2
CDH1 WILD-TYPE 58 41 89 48 106 29

Figure S30.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'CDH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S31.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CDH1 MUTATED 49 7 50
CDH1 WILD-TYPE 456 272 140

Figure S31.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'CDH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S32.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CDH1 MUTATED 12 11 29 50 1 3
CDH1 WILD-TYPE 251 140 50 211 167 49

Figure S32.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CDH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S33.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CDH1 MUTATED 5 48 39 12
CDH1 WILD-TYPE 267 129 194 264

Figure S33.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CDH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S34.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CDH1 MUTATED 14 3 66 19 2 0
CDH1 WILD-TYPE 261 133 140 115 85 120

Figure S34.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S35.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CDH1 MUTATED 9 1 20 12 32
CDH1 WILD-TYPE 169 119 46 80 80

Figure S35.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'CDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S36.  Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CDH1 MUTATED 9 55 10
CDH1 WILD-TYPE 270 126 98

Figure S36.  Get High-res Image Gene #3: 'CDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'GATA3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S37.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
GATA3 MUTATED 1 6 27 2 18 4 2 0
GATA3 WILD-TYPE 20 32 87 95 90 69 17 39

Figure S37.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'GATA3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S38.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
GATA3 MUTATED 28 22 5 1 4
GATA3 WILD-TYPE 68 130 111 88 52

Figure S38.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'GATA3 MUTATION STATUS' versus 'CN_CNMF'

P value = 9e-04 (Fisher's exact test), Q value = 0.031

Table S39.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GATA3 MUTATED 33 44 9 9 1
GATA3 WILD-TYPE 214 319 77 222 35

Figure S39.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'GATA3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0014

Table S40.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
GATA3 MUTATED 15 11 19 5 0 7
GATA3 WILD-TYPE 113 85 137 102 109 45

Figure S40.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'GATA3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0205 (Fisher's exact test), Q value = 0.34

Table S41.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
GATA3 MUTATED 12 24 10
GATA3 WILD-TYPE 133 107 108

Figure S41.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'GATA3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00077 (Fisher's exact test), Q value = 0.027

Table S42.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
GATA3 MUTATED 12 4 2 4 21 3
GATA3 WILD-TYPE 47 44 88 49 92 28

Figure S42.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'GATA3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S43.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GATA3 MUTATED 77 3 16
GATA3 WILD-TYPE 428 276 174

Figure S43.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'GATA3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S44.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GATA3 MUTATED 46 14 3 33 0 0
GATA3 WILD-TYPE 217 137 76 228 168 52

Figure S44.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'GATA3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00177 (Fisher's exact test), Q value = 0.056

Table S45.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GATA3 MUTATED 14 14 28 39
GATA3 WILD-TYPE 258 163 205 237

Figure S45.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'GATA3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S46.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GATA3 MUTATED 34 7 11 24 19 0
GATA3 WILD-TYPE 241 129 195 110 68 120

Figure S46.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'GATA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S47.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
GATA3 MUTATED 33 0 5 10 9
GATA3 WILD-TYPE 145 120 61 82 103

Figure S47.  Get High-res Image Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'GATA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 0.75

Table S48.  Gene #4: 'GATA3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
GATA3 MUTATED 30 12 15
GATA3 WILD-TYPE 249 169 93
'MAP3K1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 9e-05 (Fisher's exact test), Q value = 0.004

Table S49.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MAP3K1 MUTATED 5 1 12 1 16 1 0 3
MAP3K1 WILD-TYPE 16 37 102 96 92 72 19 36

Figure S48.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'MAP3K1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00016 (Fisher's exact test), Q value = 0.0067

Table S50.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MAP3K1 MUTATED 9 13 4 1 12
MAP3K1 WILD-TYPE 87 139 112 88 44

Figure S49.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MAP3K1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00247 (Fisher's exact test), Q value = 0.072

Table S51.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MAP3K1 MUTATED 15 39 7 6 3
MAP3K1 WILD-TYPE 232 324 79 225 33

Figure S50.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'MAP3K1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.78

Table S52.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MAP3K1 MUTATED 9 3 14 7 2 3
MAP3K1 WILD-TYPE 119 93 142 100 107 49
'MAP3K1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00078 (Fisher's exact test), Q value = 0.027

Table S53.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MAP3K1 MUTATED 4 20 12
MAP3K1 WILD-TYPE 141 111 106

Figure S51.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'MAP3K1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S54.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MAP3K1 MUTATED 16 7 1 7 5 0
MAP3K1 WILD-TYPE 43 41 89 46 108 31

Figure S52.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'MAP3K1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00045 (Fisher's exact test), Q value = 0.017

Table S55.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MAP3K1 MUTATED 47 7 16
MAP3K1 WILD-TYPE 458 272 174

Figure S53.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MAP3K1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00022 (Fisher's exact test), Q value = 0.0089

Table S56.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MAP3K1 MUTATED 31 8 7 21 3 0
MAP3K1 WILD-TYPE 232 143 72 240 165 52

Figure S54.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00046 (Fisher's exact test), Q value = 0.017

Table S57.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MAP3K1 MUTATED 6 16 23 25
MAP3K1 WILD-TYPE 266 161 210 251

Figure S55.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00105 (Fisher's exact test), Q value = 0.035

Table S58.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MAP3K1 MUTATED 19 4 24 10 11 2
MAP3K1 WILD-TYPE 256 132 182 124 76 118

Figure S56.  Get High-res Image Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 0.75

Table S59.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MAP3K1 MUTATED 15 3 3 10 7
MAP3K1 WILD-TYPE 163 117 63 82 105
'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.132 (Fisher's exact test), Q value = 0.75

Table S60.  Gene #5: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MAP3K1 MUTATED 15 11 12
MAP3K1 WILD-TYPE 264 170 96
'RUNX1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.016 (Fisher's exact test), Q value = 0.28

Table S61.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RUNX1 MUTATED 3 1 3 0 5 2 0 4
RUNX1 WILD-TYPE 18 37 111 97 103 71 19 35

Figure S57.  Get High-res Image Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'RUNX1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0849 (Fisher's exact test), Q value = 0.68

Table S62.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RUNX1 MUTATED 3 10 3 0 2
RUNX1 WILD-TYPE 93 142 113 89 54
'RUNX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00928 (Fisher's exact test), Q value = 0.2

Table S63.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RUNX1 MUTATED 4 16 6 2 0
RUNX1 WILD-TYPE 243 347 80 229 36

Figure S58.  Get High-res Image Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RUNX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 0.88

Table S64.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
RUNX1 MUTATED 1 4 6 5 1 2
RUNX1 WILD-TYPE 127 92 150 102 108 50
'RUNX1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S65.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
RUNX1 MUTATED 4 3 3
RUNX1 WILD-TYPE 141 128 115
'RUNX1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.331 (Fisher's exact test), Q value = 0.94

Table S66.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
RUNX1 MUTATED 1 2 0 2 4 1
RUNX1 WILD-TYPE 58 46 90 51 109 30
'RUNX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0647 (Fisher's exact test), Q value = 0.61

Table S67.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RUNX1 MUTATED 15 4 10
RUNX1 WILD-TYPE 490 275 180
'RUNX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0118 (Fisher's exact test), Q value = 0.23

Table S68.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RUNX1 MUTATED 4 9 4 11 1 0
RUNX1 WILD-TYPE 259 142 75 250 167 52

Figure S59.  Get High-res Image Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'RUNX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.021 (Fisher's exact test), Q value = 0.34

Table S69.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RUNX1 MUTATED 2 9 7 11
RUNX1 WILD-TYPE 270 168 226 265

Figure S60.  Get High-res Image Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'RUNX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.405 (Fisher's exact test), Q value = 0.98

Table S70.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RUNX1 MUTATED 11 2 7 6 2 1
RUNX1 WILD-TYPE 264 134 199 128 85 119
'RUNX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 0.93

Table S71.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
RUNX1 MUTATED 5 2 1 6 5
RUNX1 WILD-TYPE 173 118 65 86 107
'RUNX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S72.  Gene #6: 'RUNX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
RUNX1 MUTATED 7 8 4
RUNX1 WILD-TYPE 272 173 104
'PTEN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.93

Table S73.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PTEN MUTATED 2 2 3 1 4 1 0 0
PTEN WILD-TYPE 19 36 111 96 104 72 19 39
'PTEN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S74.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PTEN MUTATED 3 5 3 1 1
PTEN WILD-TYPE 93 147 113 88 55
'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 0.8

Table S75.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PTEN MUTATED 6 14 7 8 0
PTEN WILD-TYPE 241 349 79 223 36
'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.423 (Fisher's exact test), Q value = 0.98

Table S76.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PTEN MUTATED 4 6 7 7 5 0
PTEN WILD-TYPE 124 90 149 100 104 52
'PTEN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S77.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PTEN MUTATED 3 4 3
PTEN WILD-TYPE 142 127 115
'PTEN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S78.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PTEN MUTATED 2 3 2 0 3 0
PTEN WILD-TYPE 57 45 88 53 110 31
'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S79.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PTEN MUTATED 18 10 7
PTEN WILD-TYPE 487 269 183
'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S80.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PTEN MUTATED 7 6 5 9 5 3
PTEN WILD-TYPE 256 145 74 252 163 49
'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.134 (Fisher's exact test), Q value = 0.76

Table S81.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PTEN MUTATED 7 12 7 9
PTEN WILD-TYPE 265 165 226 267
'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S82.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PTEN MUTATED 12 5 10 3 1 4
PTEN WILD-TYPE 263 131 196 131 86 116
'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S83.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
PTEN MUTATED 7 3 3 5 7
PTEN WILD-TYPE 171 117 63 87 105
'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.828 (Fisher's exact test), Q value = 1

Table S84.  Gene #7: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
PTEN MUTATED 11 9 5
PTEN WILD-TYPE 268 172 103
'ARID1A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.93

Table S85.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ARID1A MUTATED 3 1 4 2 3 1 0 1
ARID1A WILD-TYPE 18 37 110 95 105 72 19 38
'ARID1A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.941 (Fisher's exact test), Q value = 1

Table S86.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ARID1A MUTATED 4 5 3 2 1
ARID1A WILD-TYPE 92 147 113 87 55
'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0388 (Fisher's exact test), Q value = 0.5

Table S87.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ARID1A MUTATED 12 9 0 3 2
ARID1A WILD-TYPE 235 354 86 228 34

Figure S61.  Get High-res Image Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0982 (Fisher's exact test), Q value = 0.72

Table S88.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ARID1A MUTATED 8 1 5 1 1 2
ARID1A WILD-TYPE 120 95 151 106 108 50
'ARID1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S89.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ARID1A MUTATED 4 3 3
ARID1A WILD-TYPE 141 128 115
'ARID1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 0.85

Table S90.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ARID1A MUTATED 2 0 1 0 5 2
ARID1A WILD-TYPE 57 48 89 53 108 29
'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.347 (Fisher's exact test), Q value = 0.96

Table S91.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ARID1A MUTATED 18 5 4
ARID1A WILD-TYPE 487 274 186
'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S92.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ARID1A MUTATED 8 5 1 10 2 1
ARID1A WILD-TYPE 255 146 78 251 166 51
'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S93.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ARID1A MUTATED 5 5 8 9
ARID1A WILD-TYPE 267 172 225 267
'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.403 (Fisher's exact test), Q value = 0.98

Table S94.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ARID1A MUTATED 8 5 3 4 5 2
ARID1A WILD-TYPE 267 131 203 130 82 118
'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.78

Table S95.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ARID1A MUTATED 5 0 3 1 2
ARID1A WILD-TYPE 173 120 63 91 110
'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S96.  Gene #8: 'ARID1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ARID1A MUTATED 4 5 2
ARID1A WILD-TYPE 275 176 106
'CBFB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0964 (Fisher's exact test), Q value = 0.71

Table S97.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CBFB MUTATED 1 1 0 1 6 2 0 0
CBFB WILD-TYPE 20 37 114 96 102 71 19 39
'CBFB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.216 (Fisher's exact test), Q value = 0.87

Table S98.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CBFB MUTATED 0 6 2 1 2
CBFB WILD-TYPE 96 146 114 88 54
'CBFB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.068 (Fisher's exact test), Q value = 0.62

Table S99.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CBFB MUTATED 6 12 4 1 0
CBFB WILD-TYPE 241 351 82 230 36
'CBFB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00011 (Fisher's exact test), Q value = 0.0047

Table S100.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CBFB MUTATED 0 2 12 1 0 0
CBFB WILD-TYPE 128 94 144 106 109 52

Figure S62.  Get High-res Image Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CBFB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.75

Table S101.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CBFB MUTATED 1 6 3
CBFB WILD-TYPE 144 125 115
'CBFB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.113 (Fisher's exact test), Q value = 0.75

Table S102.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CBFB MUTATED 5 1 2 1 1 0
CBFB WILD-TYPE 54 47 88 52 112 31
'CBFB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0736 (Fisher's exact test), Q value = 0.64

Table S103.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CBFB MUTATED 16 2 5
CBFB WILD-TYPE 489 277 185
'CBFB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S104.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CBFB MUTATED 7 3 2 9 1 1
CBFB WILD-TYPE 256 148 77 252 167 51
'CBFB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0218 (Fisher's exact test), Q value = 0.35

Table S105.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CBFB MUTATED 1 6 9 6
CBFB WILD-TYPE 271 171 224 270

Figure S63.  Get High-res Image Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'CBFB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00046

Table S106.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CBFB MUTATED 6 0 3 12 1 0
CBFB WILD-TYPE 269 136 203 122 86 120

Figure S64.  Get High-res Image Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CBFB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0198 (Fisher's exact test), Q value = 0.33

Table S107.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CBFB MUTATED 6 0 1 6 1
CBFB WILD-TYPE 172 120 65 86 111

Figure S65.  Get High-res Image Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'CBFB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00037 (Fisher's exact test), Q value = 0.014

Table S108.  Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CBFB MUTATED 4 1 9
CBFB WILD-TYPE 275 180 99

Figure S66.  Get High-res Image Gene #9: 'CBFB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'MLL3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S109.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MLL3 MUTATED 1 1 8 5 12 4 1 4
MLL3 WILD-TYPE 20 37 106 92 96 69 18 35
'MLL3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.155 (Fisher's exact test), Q value = 0.78

Table S110.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MLL3 MUTATED 6 10 6 5 9
MLL3 WILD-TYPE 90 142 110 84 47
'MLL3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S111.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MLL3 MUTATED 17 29 7 12 2
MLL3 WILD-TYPE 230 334 79 219 34
'MLL3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.129 (Fisher's exact test), Q value = 0.75

Table S112.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MLL3 MUTATED 11 11 15 4 4 5
MLL3 WILD-TYPE 117 85 141 103 105 47
'MLL3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S113.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MLL3 MUTATED 10 6 9
MLL3 WILD-TYPE 135 125 109
'MLL3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S114.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MLL3 MUTATED 6 4 7 2 4 2
MLL3 WILD-TYPE 53 44 83 51 109 29
'MLL3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.241 (Fisher's exact test), Q value = 0.91

Table S115.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MLL3 MUTATED 42 14 13
MLL3 WILD-TYPE 463 265 177
'MLL3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S116.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MLL3 MUTATED 21 15 3 19 8 3
MLL3 WILD-TYPE 242 136 76 242 160 49
'MLL3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 0.87

Table S117.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MLL3 MUTATED 12 12 18 24
MLL3 WILD-TYPE 260 165 215 252
'MLL3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 0.78

Table S118.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MLL3 MUTATED 18 7 14 16 7 4
MLL3 WILD-TYPE 257 129 192 118 80 116
'MLL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 0.98

Table S119.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MLL3 MUTATED 16 4 4 5 8
MLL3 WILD-TYPE 162 116 62 87 104
'MLL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.93

Table S120.  Gene #10: 'MLL3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MLL3 MUTATED 14 14 9
MLL3 WILD-TYPE 265 167 99
'FOXA1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.369 (Fisher's exact test), Q value = 0.98

Table S121.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
FOXA1 MUTATED 0 0 3 0 1 2 0 2
FOXA1 WILD-TYPE 21 38 111 97 107 71 19 37
'FOXA1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S122.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
FOXA1 MUTATED 3 2 2 0 1
FOXA1 WILD-TYPE 93 150 114 89 55
'FOXA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.95

Table S123.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
FOXA1 MUTATED 6 11 3 2 1
FOXA1 WILD-TYPE 241 352 83 229 35
'FOXA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0562 (Fisher's exact test), Q value = 0.59

Table S124.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
FOXA1 MUTATED 3 7 4 2 0 1
FOXA1 WILD-TYPE 125 89 152 105 109 51
'FOXA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S125.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
FOXA1 MUTATED 2 3 2
FOXA1 WILD-TYPE 143 128 116
'FOXA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S126.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
FOXA1 MUTATED 1 1 1 0 4 0
FOXA1 WILD-TYPE 58 47 89 53 109 31
'FOXA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0549 (Fisher's exact test), Q value = 0.59

Table S127.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
FOXA1 MUTATED 14 2 7
FOXA1 WILD-TYPE 491 277 183
'FOXA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.158 (Fisher's exact test), Q value = 0.78

Table S128.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
FOXA1 MUTATED 5 5 1 11 1 0
FOXA1 WILD-TYPE 258 146 78 250 167 52
'FOXA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0235 (Fisher's exact test), Q value = 0.37

Table S129.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
FOXA1 MUTATED 3 7 10 3
FOXA1 WILD-TYPE 269 170 223 273

Figure S67.  Get High-res Image Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'FOXA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0264 (Fisher's exact test), Q value = 0.39

Table S130.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
FOXA1 MUTATED 3 2 6 9 2 1
FOXA1 WILD-TYPE 272 134 200 125 85 119

Figure S68.  Get High-res Image Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'FOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.84

Table S131.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
FOXA1 MUTATED 6 0 3 2 3
FOXA1 WILD-TYPE 172 120 63 90 109
'FOXA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S132.  Gene #11: 'FOXA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
FOXA1 MUTATED 5 6 3
FOXA1 WILD-TYPE 274 175 105
'MAP2K4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0587 (Fisher's exact test), Q value = 0.6

Table S133.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MAP2K4 MUTATED 0 3 3 0 8 2 1 2
MAP2K4 WILD-TYPE 21 35 111 97 100 71 18 37
'MAP2K4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00452 (Fisher's exact test), Q value = 0.12

Table S134.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MAP2K4 MUTATED 2 9 2 0 6
MAP2K4 WILD-TYPE 94 143 114 89 50

Figure S69.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MAP2K4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0629 (Fisher's exact test), Q value = 0.6

Table S135.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MAP2K4 MUTATED 7 14 5 3 3
MAP2K4 WILD-TYPE 240 349 81 228 33
'MAP2K4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00957 (Fisher's exact test), Q value = 0.2

Table S136.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MAP2K4 MUTATED 9 3 10 1 0 2
MAP2K4 WILD-TYPE 119 93 146 106 109 50

Figure S70.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'MAP2K4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00206 (Fisher's exact test), Q value = 0.064

Table S137.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MAP2K4 MUTATED 0 5 8
MAP2K4 WILD-TYPE 145 126 110

Figure S71.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'MAP2K4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 0.86

Table S138.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MAP2K4 MUTATED 2 4 1 3 3 0
MAP2K4 WILD-TYPE 57 44 89 50 110 31
'MAP2K4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00307 (Fisher's exact test), Q value = 0.086

Table S139.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MAP2K4 MUTATED 25 2 5
MAP2K4 WILD-TYPE 480 277 185

Figure S72.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MAP2K4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00377 (Fisher's exact test), Q value = 0.1

Table S140.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MAP2K4 MUTATED 17 4 2 9 0 0
MAP2K4 WILD-TYPE 246 147 77 252 168 52

Figure S73.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'MAP2K4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0117 (Fisher's exact test), Q value = 0.23

Table S141.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MAP2K4 MUTATED 3 5 7 17
MAP2K4 WILD-TYPE 269 172 226 259

Figure S74.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'MAP2K4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 4e-04 (Fisher's exact test), Q value = 0.015

Table S142.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MAP2K4 MUTATED 12 1 3 10 6 0
MAP2K4 WILD-TYPE 263 135 203 124 81 120

Figure S75.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'MAP2K4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0115 (Fisher's exact test), Q value = 0.23

Table S143.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MAP2K4 MUTATED 11 0 0 3 3
MAP2K4 WILD-TYPE 167 120 66 89 109

Figure S76.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'MAP2K4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0114 (Fisher's exact test), Q value = 0.23

Table S144.  Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MAP2K4 MUTATED 7 2 8
MAP2K4 WILD-TYPE 272 179 100

Figure S77.  Get High-res Image Gene #12: 'MAP2K4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RBMX MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 0.98

Table S145.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RBMX MUTATED 0 0 0 3 2 0 0 1
RBMX WILD-TYPE 21 38 114 94 106 73 19 38
'RBMX MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 0.75

Table S146.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RBMX MUTATED 0 3 0 3 0
RBMX WILD-TYPE 96 149 116 86 56
'RBMX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0679 (Fisher's exact test), Q value = 0.62

Table S147.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RBMX MUTATED 0 6 1 6 1
RBMX WILD-TYPE 247 357 85 225 35
'RBMX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 0.75

Table S148.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
RBMX MUTATED 0 4 1 2 3 1
RBMX WILD-TYPE 128 92 155 105 106 51
'RBMX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.556 (Fisher's exact test), Q value = 1

Table S149.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
RBMX MUTATED 2 2 0
RBMX WILD-TYPE 143 129 118
'RBMX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S150.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
RBMX MUTATED 1 0 2 0 1 0
RBMX WILD-TYPE 58 48 88 53 112 31
'RBMX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.149 (Fisher's exact test), Q value = 0.77

Table S151.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RBMX MUTATED 4 7 3
RBMX WILD-TYPE 501 272 187
'RBMX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.126 (Fisher's exact test), Q value = 0.75

Table S152.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RBMX MUTATED 1 1 0 6 5 1
RBMX WILD-TYPE 262 150 79 255 163 51
'RBMX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.8

Table S153.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RBMX MUTATED 7 3 3 1
RBMX WILD-TYPE 265 174 230 275
'RBMX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S154.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RBMX MUTATED 4 4 2 2 0 2
RBMX WILD-TYPE 271 132 204 132 87 118
'RBMX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0465 (Fisher's exact test), Q value = 0.54

Table S155.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
RBMX MUTATED 0 4 0 1 3
RBMX WILD-TYPE 178 116 66 91 109

Figure S78.  Get High-res Image Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'RBMX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S156.  Gene #13: 'RBMX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
RBMX MUTATED 4 3 1
RBMX WILD-TYPE 275 178 107
'TBX3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S157.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TBX3 MUTATED 0 1 3 2 7 1 0 2
TBX3 WILD-TYPE 21 37 111 95 101 72 19 37
'TBX3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S158.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TBX3 MUTATED 3 6 3 1 3
TBX3 WILD-TYPE 93 146 113 88 53
'TBX3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.325 (Fisher's exact test), Q value = 0.94

Table S159.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TBX3 MUTATED 6 13 4 3 1
TBX3 WILD-TYPE 241 350 82 228 35
'TBX3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 0.75

Table S160.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TBX3 MUTATED 1 2 9 2 1 1
TBX3 WILD-TYPE 127 94 147 105 108 51
'TBX3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.084 (Fisher's exact test), Q value = 0.68

Table S161.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TBX3 MUTATED 1 3 6
TBX3 WILD-TYPE 144 128 112
'TBX3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S162.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TBX3 MUTATED 2 1 2 1 4 0
TBX3 WILD-TYPE 57 47 88 52 109 31
'TBX3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0444 (Fisher's exact test), Q value = 0.53

Table S163.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TBX3 MUTATED 15 3 9
TBX3 WILD-TYPE 490 276 181

Figure S79.  Get High-res Image Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TBX3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.133 (Fisher's exact test), Q value = 0.76

Table S164.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TBX3 MUTATED 6 2 5 11 2 1
TBX3 WILD-TYPE 257 149 74 250 166 51
'TBX3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0589 (Fisher's exact test), Q value = 0.6

Table S165.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TBX3 MUTATED 5 4 13 5
TBX3 WILD-TYPE 267 173 220 271
'TBX3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.124 (Fisher's exact test), Q value = 0.75

Table S166.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TBX3 MUTATED 5 2 8 6 5 1
TBX3 WILD-TYPE 270 134 198 128 82 119
'TBX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S167.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TBX3 MUTATED 3 2 3 2 4
TBX3 WILD-TYPE 175 118 63 90 108
'TBX3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S168.  Gene #14: 'TBX3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TBX3 MUTATED 6 6 2
TBX3 WILD-TYPE 273 175 106
'RB1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S169.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RB1 MUTATED 0 0 2 4 2 2 0 0
RB1 WILD-TYPE 21 38 112 93 106 71 19 39
'RB1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.305 (Fisher's exact test), Q value = 0.93

Table S170.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RB1 MUTATED 2 1 4 3 0
RB1 WILD-TYPE 94 151 112 86 56
'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.78

Table S171.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RB1 MUTATED 4 4 4 7 0
RB1 WILD-TYPE 243 359 82 224 36
'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0306 (Fisher's exact test), Q value = 0.42

Table S172.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
RB1 MUTATED 0 3 2 0 5 1
RB1 WILD-TYPE 128 93 154 107 104 51

Figure S80.  Get High-res Image Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'RB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.484 (Fisher's exact test), Q value = 1

Table S173.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
RB1 MUTATED 4 4 1
RB1 WILD-TYPE 141 127 117
'RB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S174.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
RB1 MUTATED 1 0 4 2 2 0
RB1 WILD-TYPE 58 48 86 51 111 31
'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0273 (Fisher's exact test), Q value = 0.4

Table S175.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RB1 MUTATED 10 9 0
RB1 WILD-TYPE 495 270 190

Figure S81.  Get High-res Image Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.26 (Fisher's exact test), Q value = 0.92

Table S176.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RB1 MUTATED 4 5 0 3 6 1
RB1 WILD-TYPE 259 146 79 258 162 51
'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0566 (Fisher's exact test), Q value = 0.59

Table S177.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RB1 MUTATED 8 0 2 6
RB1 WILD-TYPE 264 177 231 270
'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0264 (Fisher's exact test), Q value = 0.39

Table S178.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RB1 MUTATED 5 6 0 3 0 2
RB1 WILD-TYPE 270 130 206 131 87 118

Figure S82.  Get High-res Image Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0929 (Fisher's exact test), Q value = 0.7

Table S179.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
RB1 MUTATED 2 6 0 3 1
RB1 WILD-TYPE 176 114 66 89 111
'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.211 (Fisher's exact test), Q value = 0.86

Table S180.  Gene #15: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
RB1 MUTATED 8 1 3
RB1 WILD-TYPE 271 180 105
'THEM5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.264 (Fisher's exact test), Q value = 0.93

Table S181.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
THEM5 MUTATED 1 0 1 0 3 0 0 0
THEM5 WILD-TYPE 20 38 113 97 105 73 19 39
'THEM5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S182.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
THEM5 MUTATED 1 2 1 0 1
THEM5 WILD-TYPE 95 150 115 89 55
'THEM5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0613 (Fisher's exact test), Q value = 0.6

Table S183.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
THEM5 MUTATED 4 2 3 1 1
THEM5 WILD-TYPE 243 361 83 230 35
'THEM5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S184.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
THEM5 MUTATED 2 1 2 3 0 0
THEM5 WILD-TYPE 126 95 154 104 109 52
'THEM5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.86

Table S185.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
THEM5 MUTATED 1 3 0
THEM5 WILD-TYPE 144 128 118
'THEM5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.388 (Fisher's exact test), Q value = 0.98

Table S186.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
THEM5 MUTATED 2 0 0 0 2 0
THEM5 WILD-TYPE 57 48 90 53 111 31
'THEM5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S187.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
THEM5 MUTATED 6 2 3
THEM5 WILD-TYPE 499 277 187
'THEM5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S188.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
THEM5 MUTATED 5 2 1 2 1 0
THEM5 WILD-TYPE 258 149 78 259 167 52
'THEM5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S189.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
THEM5 MUTATED 2 2 4 2
THEM5 WILD-TYPE 270 175 229 274
'THEM5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S190.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
THEM5 MUTATED 5 0 3 0 1 1
THEM5 WILD-TYPE 270 136 203 134 86 119
'THEM5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0401 (Fisher's exact test), Q value = 0.5

Table S191.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
THEM5 MUTATED 0 1 2 0 3
THEM5 WILD-TYPE 178 119 64 92 109

Figure S83.  Get High-res Image Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'THEM5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.285 (Fisher's exact test), Q value = 0.93

Table S192.  Gene #16: 'THEM5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
THEM5 MUTATED 2 4 0
THEM5 WILD-TYPE 277 177 108
'NF1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S193.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
NF1 MUTATED 1 0 2 3 4 2 0 3
NF1 WILD-TYPE 20 38 112 94 104 71 19 36
'NF1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S194.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
NF1 MUTATED 2 4 3 3 3
NF1 WILD-TYPE 94 148 113 86 53
'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.563 (Fisher's exact test), Q value = 1

Table S195.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
NF1 MUTATED 4 13 3 7 0
NF1 WILD-TYPE 243 350 83 224 36
'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S196.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
NF1 MUTATED 2 4 3 6 3 1
NF1 WILD-TYPE 126 92 153 101 106 51
'NF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S197.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
NF1 MUTATED 4 6 4
NF1 WILD-TYPE 141 125 114
'NF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 0.88

Table S198.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
NF1 MUTATED 0 3 2 3 6 0
NF1 WILD-TYPE 59 45 88 50 107 31
'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 0.98

Table S199.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
NF1 MUTATED 12 11 4
NF1 WILD-TYPE 493 268 186
'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 0.98

Table S200.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
NF1 MUTATED 4 7 3 6 6 1
NF1 WILD-TYPE 259 144 76 255 162 51
'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 0.94

Table S201.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
NF1 MUTATED 6 8 4 9
NF1 WILD-TYPE 266 169 229 267
'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S202.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
NF1 MUTATED 9 5 4 2 4 3
NF1 WILD-TYPE 266 131 202 132 83 117
'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S203.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
NF1 MUTATED 4 4 1 3 3
NF1 WILD-TYPE 174 116 65 89 109
'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S204.  Gene #17: 'NF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
NF1 MUTATED 9 5 1
NF1 WILD-TYPE 270 176 107
'ACTL6B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.354 (Fisher's exact test), Q value = 0.96

Table S205.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ACTL6B MUTATED 1 0 1 2 0 2 0 0
ACTL6B WILD-TYPE 20 38 113 95 108 71 19 39
'ACTL6B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.29 (Fisher's exact test), Q value = 0.93

Table S206.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ACTL6B MUTATED 1 0 2 2 1
ACTL6B WILD-TYPE 95 152 114 87 55
'ACTL6B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0285 (Fisher's exact test), Q value = 0.4

Table S207.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ACTL6B MUTATED 1 2 0 5 2
ACTL6B WILD-TYPE 246 361 86 226 34

Figure S84.  Get High-res Image Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ACTL6B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S208.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ACTL6B MUTATED 1 1 2 0 3 0
ACTL6B WILD-TYPE 127 95 154 107 106 52
'ACTL6B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S209.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ACTL6B MUTATED 2 1 2
ACTL6B WILD-TYPE 143 130 116
'ACTL6B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.85

Table S210.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ACTL6B MUTATED 0 1 2 2 0 0
ACTL6B WILD-TYPE 59 47 88 51 113 31
'ACTL6B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S211.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ACTL6B MUTATED 6 3 1
ACTL6B WILD-TYPE 499 276 189
'ACTL6B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S212.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ACTL6B MUTATED 3 3 1 0 3 0
ACTL6B WILD-TYPE 260 148 78 261 165 52
'ACTL6B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S213.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ACTL6B MUTATED 3 2 1 4
ACTL6B WILD-TYPE 269 175 232 272
'ACTL6B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.717 (Fisher's exact test), Q value = 1

Table S214.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ACTL6B MUTATED 3 1 1 1 2 2
ACTL6B WILD-TYPE 272 135 205 133 85 118
'ACTL6B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.424 (Fisher's exact test), Q value = 0.98

Table S215.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ACTL6B MUTATED 3 0 0 0 2
ACTL6B WILD-TYPE 175 120 66 92 110
'ACTL6B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S216.  Gene #18: 'ACTL6B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ACTL6B MUTATED 3 2 0
ACTL6B WILD-TYPE 276 179 108
'SPEN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.664 (Fisher's exact test), Q value = 1

Table S217.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SPEN MUTATED 0 1 4 2 8 3 1 1
SPEN WILD-TYPE 21 37 110 95 100 70 18 38
'SPEN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.789 (Fisher's exact test), Q value = 1

Table S218.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SPEN MUTATED 4 8 5 2 1
SPEN WILD-TYPE 92 144 111 87 55
'SPEN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S219.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SPEN MUTATED 6 15 2 5 2
SPEN WILD-TYPE 241 348 84 226 34
'SPEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S220.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
SPEN MUTATED 5 5 7 5 1 1
SPEN WILD-TYPE 123 91 149 102 108 51
'SPEN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.943 (Fisher's exact test), Q value = 1

Table S221.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
SPEN MUTATED 6 4 4
SPEN WILD-TYPE 139 127 114
'SPEN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0268 (Fisher's exact test), Q value = 0.39

Table S222.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
SPEN MUTATED 1 5 2 0 3 3
SPEN WILD-TYPE 58 43 88 53 110 28

Figure S85.  Get High-res Image Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'SPEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.86

Table S223.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SPEN MUTATED 21 5 6
SPEN WILD-TYPE 484 274 184
'SPEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 0.75

Table S224.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SPEN MUTATED 6 7 1 14 2 2
SPEN WILD-TYPE 257 144 78 247 166 50
'SPEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 0.87

Table S225.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SPEN MUTATED 5 5 8 14
SPEN WILD-TYPE 267 172 225 262
'SPEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00876 (Fisher's exact test), Q value = 0.2

Table S226.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SPEN MUTATED 15 0 4 8 3 2
SPEN WILD-TYPE 260 136 202 126 84 118

Figure S86.  Get High-res Image Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'SPEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.094 (Fisher's exact test), Q value = 0.7

Table S227.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SPEN MUTATED 5 1 4 0 3
SPEN WILD-TYPE 173 119 62 92 109
'SPEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S228.  Gene #19: 'SPEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SPEN MUTATED 7 5 1
SPEN WILD-TYPE 272 176 107
'CDKN1B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S229.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CDKN1B MUTATED 0 0 1 0 3 1 0 1
CDKN1B WILD-TYPE 21 38 113 97 105 72 19 38
'CDKN1B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S230.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CDKN1B MUTATED 1 3 1 0 1
CDKN1B WILD-TYPE 95 149 115 89 55
'CDKN1B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0689 (Fisher's exact test), Q value = 0.62

Table S231.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CDKN1B MUTATED 0 5 3 2 0
CDKN1B WILD-TYPE 247 358 83 229 36
'CDKN1B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.77

Table S232.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CDKN1B MUTATED 0 0 4 1 0 0
CDKN1B WILD-TYPE 128 96 152 106 109 52
'CDKN1B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S233.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CDKN1B MUTATED 1 2 2
CDKN1B WILD-TYPE 144 129 116
'CDKN1B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S234.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CDKN1B MUTATED 2 0 0 2 1 0
CDKN1B WILD-TYPE 57 48 90 51 112 31
'CDKN1B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.1 (Fisher's exact test), Q value = 0.72

Table S235.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CDKN1B MUTATED 7 0 3
CDKN1B WILD-TYPE 498 279 187
'CDKN1B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S236.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CDKN1B MUTATED 2 2 1 5 0 0
CDKN1B WILD-TYPE 261 149 78 256 168 52
'CDKN1B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S237.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CDKN1B MUTATED 1 3 2 4
CDKN1B WILD-TYPE 271 174 231 272
'CDKN1B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 0.8

Table S238.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CDKN1B MUTATED 3 0 3 4 0 0
CDKN1B WILD-TYPE 272 136 203 130 87 120
'CDKN1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 0.98

Table S239.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CDKN1B MUTATED 1 0 1 2 1
CDKN1B WILD-TYPE 177 120 65 90 111
'CDKN1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0149 (Fisher's exact test), Q value = 0.27

Table S240.  Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CDKN1B MUTATED 0 2 3
CDKN1B WILD-TYPE 279 179 105

Figure S87.  Get High-res Image Gene #20: 'CDKN1B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NCOR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S241.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
NCOR1 MUTATED 0 2 4 3 7 3 0 0
NCOR1 WILD-TYPE 21 36 110 94 101 70 19 39
'NCOR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.968 (Fisher's exact test), Q value = 1

Table S242.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
NCOR1 MUTATED 3 6 4 3 3
NCOR1 WILD-TYPE 93 146 112 86 53
'NCOR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S243.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
NCOR1 MUTATED 11 17 2 8 1
NCOR1 WILD-TYPE 236 346 84 223 35
'NCOR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S244.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
NCOR1 MUTATED 5 6 8 4 4 3
NCOR1 WILD-TYPE 123 90 148 103 105 49
'NCOR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.98

Table S245.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
NCOR1 MUTATED 5 2 5
NCOR1 WILD-TYPE 140 129 113
'NCOR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.425 (Fisher's exact test), Q value = 0.98

Table S246.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
NCOR1 MUTATED 1 3 2 2 2 2
NCOR1 WILD-TYPE 58 45 88 51 111 29
'NCOR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S247.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
NCOR1 MUTATED 24 10 7
NCOR1 WILD-TYPE 481 269 183
'NCOR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.389 (Fisher's exact test), Q value = 0.98

Table S248.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
NCOR1 MUTATED 7 11 3 12 6 2
NCOR1 WILD-TYPE 256 140 76 249 162 50
'NCOR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S249.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
NCOR1 MUTATED 10 9 12 10
NCOR1 WILD-TYPE 262 168 221 266
'NCOR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 0.75

Table S250.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
NCOR1 MUTATED 18 5 7 7 0 4
NCOR1 WILD-TYPE 257 131 199 127 87 116
'NCOR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.718 (Fisher's exact test), Q value = 1

Table S251.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
NCOR1 MUTATED 7 4 3 1 4
NCOR1 WILD-TYPE 171 116 63 91 108
'NCOR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S252.  Gene #21: 'NCOR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
NCOR1 MUTATED 8 7 4
NCOR1 WILD-TYPE 271 174 104
'SF3B1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S253.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SF3B1 MUTATED 0 0 1 1 3 2 0 1
SF3B1 WILD-TYPE 21 38 113 96 105 71 19 38
'SF3B1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S254.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SF3B1 MUTATED 1 4 2 1 0
SF3B1 WILD-TYPE 95 148 114 88 56
'SF3B1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S255.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SF3B1 MUTATED 7 6 1 2 0
SF3B1 WILD-TYPE 240 357 85 229 36
'SF3B1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0906 (Fisher's exact test), Q value = 0.69

Table S256.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
SF3B1 MUTATED 5 3 5 0 0 1
SF3B1 WILD-TYPE 123 93 151 107 109 51
'SF3B1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 1

Table S257.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
SF3B1 MUTATED 1 1 3
SF3B1 WILD-TYPE 144 130 115
'SF3B1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0788 (Fisher's exact test), Q value = 0.66

Table S258.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
SF3B1 MUTATED 0 2 1 2 0 0
SF3B1 WILD-TYPE 59 46 89 51 113 31
'SF3B1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 0.93

Table S259.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SF3B1 MUTATED 11 2 3
SF3B1 WILD-TYPE 494 277 187
'SF3B1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 0.96

Table S260.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SF3B1 MUTATED 5 4 3 3 1 0
SF3B1 WILD-TYPE 258 147 76 258 167 52
'SF3B1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 0.92

Table S261.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SF3B1 MUTATED 2 3 7 4
SF3B1 WILD-TYPE 270 174 226 272
'SF3B1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 0.98

Table S262.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SF3B1 MUTATED 2 2 5 3 3 1
SF3B1 WILD-TYPE 273 134 201 131 84 119
'SF3B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 0.96

Table S263.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SF3B1 MUTATED 1 0 1 2 2
SF3B1 WILD-TYPE 177 120 65 90 110
'SF3B1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 0.91

Table S264.  Gene #22: 'SF3B1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SF3B1 MUTATED 1 3 2
SF3B1 WILD-TYPE 278 178 106
'ZFP36L1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 0.98

Table S265.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ZFP36L1 MUTATED 1 0 1 0 1 1 0 1
ZFP36L1 WILD-TYPE 20 38 113 97 107 72 19 38
'ZFP36L1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S266.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ZFP36L1 MUTATED 1 2 2 0 0
ZFP36L1 WILD-TYPE 95 150 114 89 56
'ZFP36L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00754 (Fisher's exact test), Q value = 0.17

Table S267.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ZFP36L1 MUTATED 4 1 3 0 1
ZFP36L1 WILD-TYPE 243 362 83 231 35

Figure S88.  Get High-res Image Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ZFP36L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.93

Table S268.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ZFP36L1 MUTATED 2 2 0 0 1 0
ZFP36L1 WILD-TYPE 126 94 156 107 108 52
'ZFP36L1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0267 (Fisher's exact test), Q value = 0.39

Table S269.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ZFP36L1 MUTATED 0 0 3
ZFP36L1 WILD-TYPE 145 131 115

Figure S89.  Get High-res Image Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'ZFP36L1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0499 (Fisher's exact test), Q value = 0.56

Table S270.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ZFP36L1 MUTATED 0 1 0 2 0 0
ZFP36L1 WILD-TYPE 59 47 90 51 113 31

Figure S90.  Get High-res Image Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'ZFP36L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.254 (Fisher's exact test), Q value = 0.92

Table S271.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ZFP36L1 MUTATED 7 2 0
ZFP36L1 WILD-TYPE 498 277 190
'ZFP36L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.535 (Fisher's exact test), Q value = 1

Table S272.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ZFP36L1 MUTATED 4 2 0 1 1 1
ZFP36L1 WILD-TYPE 259 149 79 260 167 51
'ZFP36L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S273.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ZFP36L1 MUTATED 3 1 3 2
ZFP36L1 WILD-TYPE 269 176 230 274
'ZFP36L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S274.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ZFP36L1 MUTATED 4 1 3 0 0 1
ZFP36L1 WILD-TYPE 271 135 203 134 87 119
'ZFP36L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.93 (Fisher's exact test), Q value = 1

Table S275.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ZFP36L1 MUTATED 2 1 1 0 1
ZFP36L1 WILD-TYPE 176 119 65 92 111
'ZFP36L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.711 (Fisher's exact test), Q value = 1

Table S276.  Gene #23: 'ZFP36L1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ZFP36L1 MUTATED 3 2 0
ZFP36L1 WILD-TYPE 276 179 108
'KRAS MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S277.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
KRAS MUTATED 0 0 0 1 2 0 0 1
KRAS WILD-TYPE 21 38 114 96 106 73 19 38
'KRAS MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S278.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
KRAS MUTATED 0 2 1 0 1
KRAS WILD-TYPE 96 150 115 89 55
'KRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 0.94

Table S279.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
KRAS MUTATED 0 5 0 1 0
KRAS WILD-TYPE 247 358 86 230 36
'KRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S280.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
KRAS MUTATED 0 0 3 1 0 0
KRAS WILD-TYPE 128 96 153 106 109 52
'KRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.86

Table S281.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
KRAS MUTATED 0 1 2
KRAS WILD-TYPE 145 130 116
'KRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.513 (Fisher's exact test), Q value = 1

Table S282.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
KRAS MUTATED 1 0 1 1 0 0
KRAS WILD-TYPE 58 48 89 52 113 31
'KRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S283.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
KRAS MUTATED 3 1 2
KRAS WILD-TYPE 502 278 188
'KRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0847 (Fisher's exact test), Q value = 0.68

Table S284.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
KRAS MUTATED 2 0 2 1 0 1
KRAS WILD-TYPE 261 151 77 260 168 51
'KRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S285.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
KRAS MUTATED 1 1 1 3
KRAS WILD-TYPE 271 176 232 273
'KRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.958 (Fisher's exact test), Q value = 1

Table S286.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
KRAS MUTATED 3 1 1 1 0 0
KRAS WILD-TYPE 272 135 205 133 87 120
'KRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S287.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
KRAS MUTATED 1 1 0 1 0
KRAS WILD-TYPE 177 119 66 91 112
'KRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.126 (Fisher's exact test), Q value = 0.75

Table S288.  Gene #24: 'KRAS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
KRAS MUTATED 1 0 2
KRAS WILD-TYPE 278 181 106
'AQP12A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S289.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
AQP12A MUTATED 0 1 1 0 1 0 0 0
AQP12A WILD-TYPE 21 37 113 97 107 73 19 39
'AQP12A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S290.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
AQP12A MUTATED 1 2 0 0 0
AQP12A WILD-TYPE 95 150 116 89 56
'AQP12A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 0.96

Table S291.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
AQP12A MUTATED 4 1 0 1 0
AQP12A WILD-TYPE 243 362 86 230 36
'AQP12A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0232 (Fisher's exact test), Q value = 0.37

Table S292.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
AQP12A MUTATED 0 3 0 0 1 0
AQP12A WILD-TYPE 128 93 156 107 108 52

Figure S91.  Get High-res Image Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'AQP12A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.86

Table S293.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
AQP12A MUTATED 0 1 2
AQP12A WILD-TYPE 145 130 116
'AQP12A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 0.99

Table S294.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
AQP12A MUTATED 0 0 0 0 3 0
AQP12A WILD-TYPE 59 48 90 53 110 31
'AQP12A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S295.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
AQP12A MUTATED 3 2 1
AQP12A WILD-TYPE 502 277 189
'AQP12A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S296.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
AQP12A MUTATED 2 1 0 2 1 0
AQP12A WILD-TYPE 261 150 79 259 167 52
'AQP12A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S297.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
AQP12A MUTATED 1 1 2 2
AQP12A WILD-TYPE 271 176 231 274
'AQP12A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S298.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
AQP12A MUTATED 1 0 1 2 1 1
AQP12A WILD-TYPE 274 136 205 132 86 119
'AQP12A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 0.98

Table S299.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
AQP12A MUTATED 2 0 1 0 0
AQP12A WILD-TYPE 176 120 65 92 112
'AQP12A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S300.  Gene #25: 'AQP12A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
AQP12A MUTATED 2 1 0
AQP12A WILD-TYPE 277 180 108
'DLG1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.341 (Fisher's exact test), Q value = 0.96

Table S301.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
DLG1 MUTATED 0 2 1 0 2 2 0 0
DLG1 WILD-TYPE 21 36 113 97 106 71 19 39
'DLG1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 0.94

Table S302.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
DLG1 MUTATED 0 4 2 0 1
DLG1 WILD-TYPE 96 148 114 89 55
'DLG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 0.98

Table S303.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
DLG1 MUTATED 1 6 2 4 0
DLG1 WILD-TYPE 246 357 84 227 36
'DLG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S304.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
DLG1 MUTATED 2 1 1 3 2 0
DLG1 WILD-TYPE 126 95 155 104 107 52
'DLG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S305.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
DLG1 MUTATED 2 3 2
DLG1 WILD-TYPE 143 128 116
'DLG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 0.75

Table S306.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
DLG1 MUTATED 2 1 0 1 1 2
DLG1 WILD-TYPE 57 47 90 52 112 29
'DLG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.75

Table S307.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
DLG1 MUTATED 4 7 2
DLG1 WILD-TYPE 501 272 188
'DLG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.84

Table S308.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
DLG1 MUTATED 1 3 1 5 1 2
DLG1 WILD-TYPE 262 148 78 256 167 50
'DLG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S309.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
DLG1 MUTATED 4 1 2 5
DLG1 WILD-TYPE 268 176 231 271
'DLG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00389 (Fisher's exact test), Q value = 0.11

Table S310.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
DLG1 MUTATED 5 6 0 0 1 0
DLG1 WILD-TYPE 270 130 206 134 86 120

Figure S92.  Get High-res Image Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'DLG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S311.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
DLG1 MUTATED 1 3 1 1 2
DLG1 WILD-TYPE 177 117 65 91 110
'DLG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S312.  Gene #26: 'DLG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
DLG1 MUTATED 4 2 2
DLG1 WILD-TYPE 275 179 106
'TCP11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S313.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TCP11 MUTATED 0 1 2 1 1 0 0 1
TCP11 WILD-TYPE 21 37 112 96 107 73 19 38
'TCP11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S314.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TCP11 MUTATED 2 3 0 1 0
TCP11 WILD-TYPE 94 149 116 88 56
'TCP11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S315.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TCP11 MUTATED 1 3 0 1 1
TCP11 WILD-TYPE 246 360 86 230 35
'TCP11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S316.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TCP11 MUTATED 2 1 2
TCP11 WILD-TYPE 143 130 116
'TCP11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.607 (Fisher's exact test), Q value = 1

Table S317.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TCP11 MUTATED 0 0 1 2 2 0
TCP11 WILD-TYPE 59 48 89 51 111 31
'TCP11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.741 (Fisher's exact test), Q value = 1

Table S318.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TCP11 MUTATED 3 1 2
TCP11 WILD-TYPE 502 278 188
'TCP11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.373 (Fisher's exact test), Q value = 0.98

Table S319.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TCP11 MUTATED 1 1 2 1 1 0
TCP11 WILD-TYPE 262 150 77 260 167 52
'TCP11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S320.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TCP11 MUTATED 1 1 2 2
TCP11 WILD-TYPE 271 176 231 274
'TCP11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S321.  Gene #27: 'TCP11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TCP11 MUTATED 2 0 2 0 1 1
TCP11 WILD-TYPE 273 136 204 134 86 119
'MYB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S322.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MYB MUTATED 0 0 2 2 4 0 0 1
MYB WILD-TYPE 21 38 112 95 104 73 19 38
'MYB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0284 (Fisher's exact test), Q value = 0.4

Table S323.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MYB MUTATED 0 2 1 2 4
MYB WILD-TYPE 96 150 115 87 52

Figure S93.  Get High-res Image Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'MYB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 0.88

Table S324.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MYB MUTATED 1 6 3 2 0
MYB WILD-TYPE 246 357 83 229 36
'MYB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 0.96

Table S325.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MYB MUTATED 0 1 1 0 2 1
MYB WILD-TYPE 128 95 155 107 107 51
'MYB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S326.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MYB MUTATED 2 2 1
MYB WILD-TYPE 143 129 117
'MYB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S327.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MYB MUTATED 2 0 1 1 1 0
MYB WILD-TYPE 57 48 89 52 112 31
'MYB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S328.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MYB MUTATED 7 3 2
MYB WILD-TYPE 498 276 188
'MYB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S329.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MYB MUTATED 4 1 0 4 3 0
MYB WILD-TYPE 259 150 79 257 165 52
'MYB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0986 (Fisher's exact test), Q value = 0.72

Table S330.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MYB MUTATED 2 1 7 2
MYB WILD-TYPE 270 176 226 274
'MYB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.124 (Fisher's exact test), Q value = 0.75

Table S331.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MYB MUTATED 3 2 0 4 2 1
MYB WILD-TYPE 272 134 206 130 85 119
'MYB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.93

Table S332.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MYB MUTATED 2 0 0 2 0
MYB WILD-TYPE 176 120 66 90 112
'MYB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00119 (Fisher's exact test), Q value = 0.039

Table S333.  Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MYB MUTATED 0 0 4
MYB WILD-TYPE 279 181 104

Figure S94.  Get High-res Image Gene #28: 'MYB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RPGR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.969 (Fisher's exact test), Q value = 1

Table S334.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RPGR MUTATED 0 1 3 3 2 2 1 1
RPGR WILD-TYPE 21 37 111 94 106 71 18 38
'RPGR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S335.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RPGR MUTATED 3 5 2 3 0
RPGR WILD-TYPE 93 147 114 86 56
'RPGR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S336.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RPGR MUTATED 5 6 2 4 0
RPGR WILD-TYPE 242 357 84 227 36
'RPGR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.39 (Fisher's exact test), Q value = 0.98

Table S337.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
RPGR MUTATED 6 1 2 3 2 0
RPGR WILD-TYPE 122 95 154 104 107 52
'RPGR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S338.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
RPGR MUTATED 5 4 2
RPGR WILD-TYPE 140 127 116
'RPGR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.93

Table S339.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
RPGR MUTATED 0 0 3 2 6 0
RPGR WILD-TYPE 59 48 87 51 107 31
'RPGR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.373 (Fisher's exact test), Q value = 0.98

Table S340.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RPGR MUTATED 9 8 2
RPGR WILD-TYPE 496 271 188
'RPGR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.983 (Fisher's exact test), Q value = 1

Table S341.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RPGR MUTATED 4 3 1 6 4 1
RPGR WILD-TYPE 259 148 78 255 164 51
'RPGR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 0.88

Table S342.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RPGR MUTATED 4 1 4 9
RPGR WILD-TYPE 268 176 229 267
'RPGR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S343.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RPGR MUTATED 8 5 3 1 1 0
RPGR WILD-TYPE 267 131 203 133 86 120
'RPGR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S344.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
RPGR MUTATED 4 1 1 0 1
RPGR WILD-TYPE 174 119 65 92 111
'RPGR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S345.  Gene #29: 'RPGR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
RPGR MUTATED 5 2 0
RPGR WILD-TYPE 274 179 108
'TBL1XR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.78

Table S346.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TBL1XR1 MUTATED 1 0 1 0 5 1 0 0
TBL1XR1 WILD-TYPE 20 38 113 97 103 72 19 39
'TBL1XR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0807 (Fisher's exact test), Q value = 0.67

Table S347.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TBL1XR1 MUTATED 0 3 2 0 3
TBL1XR1 WILD-TYPE 96 149 114 89 53
'TBL1XR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0134 (Fisher's exact test), Q value = 0.26

Table S348.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TBL1XR1 MUTATED 1 5 4 0 0
TBL1XR1 WILD-TYPE 246 358 82 231 36

Figure S95.  Get High-res Image Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'TBL1XR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.596 (Fisher's exact test), Q value = 1

Table S349.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TBL1XR1 MUTATED 0 0 2 1 0 0
TBL1XR1 WILD-TYPE 128 96 154 106 109 52
'TBL1XR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 1

Table S350.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TBL1XR1 MUTATED 2 4 1
TBL1XR1 WILD-TYPE 143 127 117
'TBL1XR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.78

Table S351.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TBL1XR1 MUTATED 3 1 0 1 1 1
TBL1XR1 WILD-TYPE 56 47 90 52 112 30
'TBL1XR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.432 (Fisher's exact test), Q value = 0.99

Table S352.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TBL1XR1 MUTATED 6 1 3
TBL1XR1 WILD-TYPE 499 278 187
'TBL1XR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.434 (Fisher's exact test), Q value = 0.99

Table S353.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TBL1XR1 MUTATED 4 1 0 5 0 0
TBL1XR1 WILD-TYPE 259 150 79 256 168 52
'TBL1XR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 0.98

Table S354.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TBL1XR1 MUTATED 1 1 4 4
TBL1XR1 WILD-TYPE 271 176 229 272
'TBL1XR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S355.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TBL1XR1 MUTATED 3 1 2 3 1 0
TBL1XR1 WILD-TYPE 272 135 204 131 86 120
'TBL1XR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S356.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TBL1XR1 MUTATED 3 1 0 1 1
TBL1XR1 WILD-TYPE 175 119 66 91 111
'TBL1XR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 0.83

Table S357.  Gene #30: 'TBL1XR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TBL1XR1 MUTATED 2 1 3
TBL1XR1 WILD-TYPE 277 180 105
'KDM6A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S358.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
KDM6A MUTATED 0 1 1 2 3 0 0 1
KDM6A WILD-TYPE 21 37 113 95 105 73 19 38
'KDM6A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.344 (Fisher's exact test), Q value = 0.96

Table S359.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
KDM6A MUTATED 2 4 0 2 0
KDM6A WILD-TYPE 94 148 116 87 56
'KDM6A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 0.96

Table S360.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
KDM6A MUTATED 5 5 3 2 1
KDM6A WILD-TYPE 242 358 83 229 35
'KDM6A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.092 (Fisher's exact test), Q value = 0.69

Table S361.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
KDM6A MUTATED 3 1 1 0 2 3
KDM6A WILD-TYPE 125 95 155 107 107 49
'KDM6A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.637 (Fisher's exact test), Q value = 1

Table S362.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
KDM6A MUTATED 4 2 1
KDM6A WILD-TYPE 141 129 117
'KDM6A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.964 (Fisher's exact test), Q value = 1

Table S363.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
KDM6A MUTATED 1 1 2 0 3 0
KDM6A WILD-TYPE 58 47 88 53 110 31
'KDM6A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S364.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
KDM6A MUTATED 6 6 4
KDM6A WILD-TYPE 499 273 186
'KDM6A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 0.94

Table S365.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
KDM6A MUTATED 2 4 0 5 5 0
KDM6A WILD-TYPE 261 147 79 256 163 52
'KDM6A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S366.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
KDM6A MUTATED 5 4 2 5
KDM6A WILD-TYPE 267 173 231 271
'KDM6A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S367.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
KDM6A MUTATED 4 2 3 3 0 4
KDM6A WILD-TYPE 271 134 203 131 87 116
'KDM6A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.736 (Fisher's exact test), Q value = 1

Table S368.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
KDM6A MUTATED 4 3 0 2 1
KDM6A WILD-TYPE 174 117 66 90 111
'KDM6A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.28 (Fisher's exact test), Q value = 0.93

Table S369.  Gene #31: 'KDM6A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
KDM6A MUTATED 6 1 3
KDM6A WILD-TYPE 273 180 105
'MYH9 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 0.98

Table S370.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MYH9 MUTATED 0 1 0 2 2 1 1 1
MYH9 WILD-TYPE 21 37 114 95 106 72 18 38
'MYH9 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.421 (Fisher's exact test), Q value = 0.98

Table S371.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MYH9 MUTATED 0 4 3 1 0
MYH9 WILD-TYPE 96 148 113 88 56
'MYH9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.365 (Fisher's exact test), Q value = 0.97

Table S372.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MYH9 MUTATED 4 10 0 2 0
MYH9 WILD-TYPE 243 353 86 229 36
'MYH9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.378 (Fisher's exact test), Q value = 0.98

Table S373.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MYH9 MUTATED 1 4 5 1 2 0
MYH9 WILD-TYPE 127 92 151 106 107 52
'MYH9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S374.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MYH9 MUTATED 4 2 2
MYH9 WILD-TYPE 141 129 116
'MYH9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0541 (Fisher's exact test), Q value = 0.59

Table S375.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MYH9 MUTATED 1 0 1 2 1 3
MYH9 WILD-TYPE 58 48 89 51 112 28
'MYH9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S376.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MYH9 MUTATED 8 7 3
MYH9 WILD-TYPE 497 272 187
'MYH9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.77

Table S377.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MYH9 MUTATED 1 3 1 8 3 2
MYH9 WILD-TYPE 262 148 78 253 165 50
'MYH9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.735 (Fisher's exact test), Q value = 1

Table S378.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MYH9 MUTATED 4 4 6 4
MYH9 WILD-TYPE 268 173 227 272
'MYH9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 0.98

Table S379.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MYH9 MUTATED 3 3 7 3 0 2
MYH9 WILD-TYPE 272 133 199 131 87 118
'MYH9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S380.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MYH9 MUTATED 3 3 2 0 3
MYH9 WILD-TYPE 175 117 64 92 109
'MYH9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.261 (Fisher's exact test), Q value = 0.92

Table S381.  Gene #32: 'MYH9 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MYH9 MUTATED 6 5 0
MYH9 WILD-TYPE 273 176 108
'HLA-C MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.76

Table S382.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
HLA-C MUTATED 0 1 0 0 0 1 0 1
HLA-C WILD-TYPE 21 37 114 97 108 72 19 38
'HLA-C MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S383.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
HLA-C MUTATED 0 2 1 0 0
HLA-C WILD-TYPE 96 150 115 89 56
'HLA-C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.724 (Fisher's exact test), Q value = 1

Table S384.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
HLA-C MUTATED 2 3 0 4 0
HLA-C WILD-TYPE 245 360 86 227 36
'HLA-C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0991 (Fisher's exact test), Q value = 0.72

Table S385.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
HLA-C MUTATED 0 1 3 0 4 0
HLA-C WILD-TYPE 128 95 153 107 105 52
'HLA-C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 0.93

Table S386.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
HLA-C MUTATED 1 0 2
HLA-C WILD-TYPE 144 131 116
'HLA-C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.571 (Fisher's exact test), Q value = 1

Table S387.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
HLA-C MUTATED 0 1 0 0 2 0
HLA-C WILD-TYPE 59 47 90 53 111 31
'HLA-C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.75

Table S388.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
HLA-C MUTATED 2 5 2
HLA-C WILD-TYPE 503 274 188
'HLA-C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.579 (Fisher's exact test), Q value = 1

Table S389.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
HLA-C MUTATED 2 1 0 2 4 0
HLA-C WILD-TYPE 261 150 79 259 164 52
'HLA-C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0307 (Fisher's exact test), Q value = 0.42

Table S390.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
HLA-C MUTATED 6 2 1 0
HLA-C WILD-TYPE 266 175 232 276

Figure S96.  Get High-res Image Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'HLA-C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0111 (Fisher's exact test), Q value = 0.23

Table S391.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
HLA-C MUTATED 0 1 1 3 0 4
HLA-C WILD-TYPE 275 135 205 131 87 116

Figure S97.  Get High-res Image Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'HLA-C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0281 (Fisher's exact test), Q value = 0.4

Table S392.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
HLA-C MUTATED 0 4 0 0 1
HLA-C WILD-TYPE 178 116 66 92 111

Figure S98.  Get High-res Image Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'HLA-C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S393.  Gene #33: 'HLA-C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
HLA-C MUTATED 4 1 0
HLA-C WILD-TYPE 275 180 108
'FGFR2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.916 (Fisher's exact test), Q value = 1

Table S394.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
FGFR2 MUTATED 0 0 1 1 2 2 0 0
FGFR2 WILD-TYPE 21 38 113 96 106 71 19 39
'FGFR2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S395.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
FGFR2 MUTATED 1 1 2 1 1
FGFR2 WILD-TYPE 95 151 114 88 55
'FGFR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.94

Table S396.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
FGFR2 MUTATED 2 3 3 3 0
FGFR2 WILD-TYPE 245 360 83 228 36
'FGFR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0918 (Fisher's exact test), Q value = 0.69

Table S397.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
FGFR2 MUTATED 2 2 0 0 0 1
FGFR2 WILD-TYPE 126 94 156 107 109 51
'FGFR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S398.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
FGFR2 MUTATED 2 2 1
FGFR2 WILD-TYPE 143 129 117
'FGFR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.797 (Fisher's exact test), Q value = 1

Table S399.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
FGFR2 MUTATED 0 0 1 1 3 0
FGFR2 WILD-TYPE 59 48 89 52 110 31
'FGFR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S400.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
FGFR2 MUTATED 7 3 1
FGFR2 WILD-TYPE 498 276 189
'FGFR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 0.99

Table S401.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
FGFR2 MUTATED 2 4 0 3 1 1
FGFR2 WILD-TYPE 261 147 79 258 167 51
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.225 (Fisher's exact test), Q value = 0.88

Table S402.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
FGFR2 MUTATED 5 0 4 2
FGFR2 WILD-TYPE 267 177 229 274
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S403.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
FGFR2 MUTATED 6 1 3 0 0 1
FGFR2 WILD-TYPE 269 135 203 134 87 119
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S404.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
FGFR2 MUTATED 2 0 1 0 1
FGFR2 WILD-TYPE 176 120 65 92 111
'FGFR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S405.  Gene #34: 'FGFR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
FGFR2 MUTATED 2 2 0
FGFR2 WILD-TYPE 277 179 108
'RAB42 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 0.98

Table S406.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RAB42 MUTATED 0 0 0 3 1 0 0 0
RAB42 WILD-TYPE 21 38 114 94 107 73 19 39
'RAB42 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0705 (Fisher's exact test), Q value = 0.62

Table S407.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RAB42 MUTATED 0 1 0 3 0
RAB42 WILD-TYPE 96 151 116 86 56
'RAB42 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0406 (Fisher's exact test), Q value = 0.5

Table S408.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RAB42 MUTATED 0 0 1 3 0
RAB42 WILD-TYPE 247 363 85 228 36

Figure S99.  Get High-res Image Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'RAB42 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.93

Table S409.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
RAB42 MUTATED 1 0 2
RAB42 WILD-TYPE 144 131 116
'RAB42 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.389 (Fisher's exact test), Q value = 0.98

Table S410.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
RAB42 MUTATED 0 0 2 1 0 0
RAB42 WILD-TYPE 59 48 88 52 113 31
'RAB42 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.75

Table S411.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RAB42 MUTATED 1 3 0
RAB42 WILD-TYPE 504 276 190
'RAB42 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.155 (Fisher's exact test), Q value = 0.78

Table S412.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RAB42 MUTATED 0 0 0 1 3 0
RAB42 WILD-TYPE 263 151 79 260 165 52
'RAB42 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.232 (Fisher's exact test), Q value = 0.88

Table S413.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RAB42 MUTATED 3 0 0 1
RAB42 WILD-TYPE 269 177 233 275
'RAB42 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.01 (Fisher's exact test), Q value = 0.21

Table S414.  Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RAB42 MUTATED 0 0 0 1 0 3
RAB42 WILD-TYPE 275 136 206 133 87 117

Figure S100.  Get High-res Image Gene #35: 'RAB42 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'TFE3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S415.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TFE3 MUTATED 1 1 1 2 1 1 0 0
TFE3 WILD-TYPE 20 37 113 95 107 72 19 39
'TFE3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S416.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TFE3 MUTATED 1 2 2 2 0
TFE3 WILD-TYPE 95 150 114 87 56
'TFE3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S417.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TFE3 MUTATED 2 2 0 3 0
TFE3 WILD-TYPE 245 361 86 228 36
'TFE3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.422 (Fisher's exact test), Q value = 0.98

Table S418.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TFE3 MUTATED 1 0 0 1 1 1
TFE3 WILD-TYPE 127 96 156 106 108 51
'TFE3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S419.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TFE3 MUTATED 1 1 1
TFE3 WILD-TYPE 144 130 117
'TFE3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S420.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TFE3 MUTATED 0 0 1 0 2 0
TFE3 WILD-TYPE 59 48 89 53 111 31
'TFE3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S421.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TFE3 MUTATED 3 3 1
TFE3 WILD-TYPE 502 276 189
'TFE3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S422.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TFE3 MUTATED 2 1 0 1 2 1
TFE3 WILD-TYPE 261 150 79 260 166 51
'TFE3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S423.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TFE3 MUTATED 2 2 2 1
TFE3 WILD-TYPE 270 175 231 275
'TFE3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.427 (Fisher's exact test), Q value = 0.98

Table S424.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TFE3 MUTATED 1 3 1 1 0 1
TFE3 WILD-TYPE 274 133 205 133 87 119
'TFE3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S425.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TFE3 MUTATED 2 1 0 0 0
TFE3 WILD-TYPE 176 119 66 92 112
'TFE3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 0.93

Table S426.  Gene #36: 'TFE3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TFE3 MUTATED 3 0 0
TFE3 WILD-TYPE 276 181 108
'ZMYM3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S427.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ZMYM3 MUTATED 1 0 1 4 4 1 0 0
ZMYM3 WILD-TYPE 20 38 113 93 104 72 19 39
'ZMYM3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.44 (Fisher's exact test), Q value = 1

Table S428.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ZMYM3 MUTATED 1 4 1 4 1
ZMYM3 WILD-TYPE 95 148 115 85 55
'ZMYM3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S429.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ZMYM3 MUTATED 2 7 1 4 0
ZMYM3 WILD-TYPE 245 356 85 227 36
'ZMYM3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.93

Table S430.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ZMYM3 MUTATED 1 1 0 1 3 0
ZMYM3 WILD-TYPE 127 95 156 106 106 52
'ZMYM3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.126 (Fisher's exact test), Q value = 0.75

Table S431.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ZMYM3 MUTATED 5 2 0
ZMYM3 WILD-TYPE 140 129 118
'ZMYM3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S432.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ZMYM3 MUTATED 1 0 3 0 2 1
ZMYM3 WILD-TYPE 58 48 87 53 111 30
'ZMYM3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.78

Table S433.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ZMYM3 MUTATED 9 5 0
ZMYM3 WILD-TYPE 496 274 190
'ZMYM3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S434.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ZMYM3 MUTATED 2 3 0 5 4 0
ZMYM3 WILD-TYPE 261 148 79 256 164 52
'ZMYM3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S435.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ZMYM3 MUTATED 6 1 4 3
ZMYM3 WILD-TYPE 266 176 229 273
'ZMYM3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S436.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ZMYM3 MUTATED 6 2 2 1 1 2
ZMYM3 WILD-TYPE 269 134 204 133 86 118
'ZMYM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 0.88

Table S437.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ZMYM3 MUTATED 2 0 2 0 1
ZMYM3 WILD-TYPE 176 120 64 92 111
'ZMYM3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S438.  Gene #37: 'ZMYM3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ZMYM3 MUTATED 2 2 1
ZMYM3 WILD-TYPE 277 179 107
'ERBB2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S439.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ERBB2 MUTATED 1 1 2 1 3 3 0 1
ERBB2 WILD-TYPE 20 37 112 96 105 70 19 38
'ERBB2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S440.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ERBB2 MUTATED 2 6 3 1 0
ERBB2 WILD-TYPE 94 146 113 88 56
'ERBB2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0637 (Fisher's exact test), Q value = 0.6

Table S441.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ERBB2 MUTATED 3 10 5 2 0
ERBB2 WILD-TYPE 244 353 81 229 36
'ERBB2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00271 (Fisher's exact test), Q value = 0.077

Table S442.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ERBB2 MUTATED 0 4 1 4 0 3
ERBB2 WILD-TYPE 128 92 155 103 109 49

Figure S101.  Get High-res Image Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'ERBB2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S443.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ERBB2 MUTATED 2 2 4
ERBB2 WILD-TYPE 143 129 114
'ERBB2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.957 (Fisher's exact test), Q value = 1

Table S444.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ERBB2 MUTATED 1 1 1 1 3 1
ERBB2 WILD-TYPE 58 47 89 52 110 30
'ERBB2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.257 (Fisher's exact test), Q value = 0.92

Table S445.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ERBB2 MUTATED 10 4 7
ERBB2 WILD-TYPE 495 275 183
'ERBB2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.126 (Fisher's exact test), Q value = 0.75

Table S446.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ERBB2 MUTATED 3 4 2 8 1 3
ERBB2 WILD-TYPE 260 147 77 253 167 49
'ERBB2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.87

Table S447.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ERBB2 MUTATED 2 5 7 6
ERBB2 WILD-TYPE 270 172 226 270
'ERBB2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.106 (Fisher's exact test), Q value = 0.75

Table S448.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ERBB2 MUTATED 4 2 7 6 1 0
ERBB2 WILD-TYPE 271 134 199 128 86 120
'ERBB2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 0.94

Table S449.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ERBB2 MUTATED 1 1 1 3 3
ERBB2 WILD-TYPE 177 119 65 89 109
'ERBB2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S450.  Gene #38: 'ERBB2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ERBB2 MUTATED 3 4 2
ERBB2 WILD-TYPE 276 177 106
'CTCF MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0591 (Fisher's exact test), Q value = 0.6

Table S451.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CTCF MUTATED 1 0 2 1 8 0 0 1
CTCF WILD-TYPE 20 38 112 96 100 73 19 38
'CTCF MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0439 (Fisher's exact test), Q value = 0.53

Table S452.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CTCF MUTATED 3 3 1 1 5
CTCF WILD-TYPE 93 149 115 88 51

Figure S102.  Get High-res Image Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0174 (Fisher's exact test), Q value = 0.3

Table S453.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CTCF MUTATED 2 13 0 1 1
CTCF WILD-TYPE 245 350 86 230 35

Figure S103.  Get High-res Image Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'CTCF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00946 (Fisher's exact test), Q value = 0.2

Table S454.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CTCF MUTATED 0 1 8 2 0 0
CTCF WILD-TYPE 128 95 148 105 109 52

Figure S104.  Get High-res Image Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'CTCF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.069 (Fisher's exact test), Q value = 0.62

Table S455.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CTCF MUTATED 1 7 3
CTCF WILD-TYPE 144 124 115
'CTCF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 0.75

Table S456.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CTCF MUTATED 5 0 1 1 4 0
CTCF WILD-TYPE 54 48 89 52 109 31
'CTCF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0802 (Fisher's exact test), Q value = 0.67

Table S457.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CTCF MUTATED 12 1 4
CTCF WILD-TYPE 493 278 186
'CTCF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.369 (Fisher's exact test), Q value = 0.98

Table S458.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CTCF MUTATED 8 1 1 6 1 0
CTCF WILD-TYPE 255 150 78 255 167 52
'CTCF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0708 (Fisher's exact test), Q value = 0.62

Table S459.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CTCF MUTATED 1 2 7 7
CTCF WILD-TYPE 271 175 226 269
'CTCF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00235 (Fisher's exact test), Q value = 0.071

Table S460.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CTCF MUTATED 2 2 4 2 7 0
CTCF WILD-TYPE 273 134 202 132 80 120

Figure S105.  Get High-res Image Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'CTCF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S461.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CTCF MUTATED 4 1 0 1 1
CTCF WILD-TYPE 174 119 66 91 111
'CTCF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S462.  Gene #39: 'CTCF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CTCF MUTATED 4 1 2
CTCF WILD-TYPE 275 180 106
'FRMPD2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S463.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
FRMPD2 MUTATED 0 1 1 1 1 2 0 0
FRMPD2 WILD-TYPE 21 37 113 96 107 71 19 39
'FRMPD2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S464.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
FRMPD2 MUTATED 1 2 2 1 0
FRMPD2 WILD-TYPE 95 150 114 88 56
'FRMPD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.372 (Fisher's exact test), Q value = 0.98

Table S465.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
FRMPD2 MUTATED 2 4 0 5 1
FRMPD2 WILD-TYPE 245 359 86 226 35
'FRMPD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S466.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
FRMPD2 MUTATED 2 1 1 2 3 0
FRMPD2 WILD-TYPE 126 95 155 105 106 52
'FRMPD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S467.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
FRMPD2 MUTATED 2 0 2
FRMPD2 WILD-TYPE 143 131 116
'FRMPD2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.935 (Fisher's exact test), Q value = 1

Table S468.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
FRMPD2 MUTATED 0 0 1 1 2 0
FRMPD2 WILD-TYPE 59 48 89 52 111 31
'FRMPD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S469.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
FRMPD2 MUTATED 7 4 1
FRMPD2 WILD-TYPE 498 275 189
'FRMPD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0615 (Fisher's exact test), Q value = 0.6

Table S470.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
FRMPD2 MUTATED 0 4 0 4 4 0
FRMPD2 WILD-TYPE 263 147 79 257 164 52
'FRMPD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.424 (Fisher's exact test), Q value = 0.98

Table S471.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
FRMPD2 MUTATED 4 4 1 3
FRMPD2 WILD-TYPE 268 173 232 273
'FRMPD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S472.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
FRMPD2 MUTATED 5 1 2 1 0 3
FRMPD2 WILD-TYPE 270 135 204 133 87 117
'FRMPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.85

Table S473.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
FRMPD2 MUTATED 0 2 0 2 2
FRMPD2 WILD-TYPE 178 118 66 90 110
'FRMPD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.753 (Fisher's exact test), Q value = 1

Table S474.  Gene #40: 'FRMPD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
FRMPD2 MUTATED 2 3 1
FRMPD2 WILD-TYPE 277 178 107
'GPS2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.014 (Fisher's exact test), Q value = 0.26

Table S475.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
GPS2 MUTATED 0 4 2 0 1 0 0 1
GPS2 WILD-TYPE 21 34 112 97 107 73 19 38

Figure S106.  Get High-res Image Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'GPS2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0493 (Fisher's exact test), Q value = 0.56

Table S476.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
GPS2 MUTATED 2 6 0 0 0
GPS2 WILD-TYPE 94 146 116 89 56

Figure S107.  Get High-res Image Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'GPS2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.061 (Fisher's exact test), Q value = 0.6

Table S477.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GPS2 MUTATED 2 9 0 0 0
GPS2 WILD-TYPE 245 354 86 231 36
'GPS2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.311 (Fisher's exact test), Q value = 0.93

Table S478.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
GPS2 MUTATED 1 3 1 0 2 1
GPS2 WILD-TYPE 127 93 155 107 107 51
'GPS2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 0.94

Table S479.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
GPS2 MUTATED 0 2 2
GPS2 WILD-TYPE 145 129 116
'GPS2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S480.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
GPS2 MUTATED 1 1 0 0 2 0
GPS2 WILD-TYPE 58 47 90 53 111 31
'GPS2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 0.98

Table S481.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GPS2 MUTATED 5 2 4
GPS2 WILD-TYPE 500 277 186
'GPS2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0417 (Fisher's exact test), Q value = 0.5

Table S482.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GPS2 MUTATED 2 0 1 6 0 2
GPS2 WILD-TYPE 261 151 78 255 168 50

Figure S108.  Get High-res Image Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'GPS2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 0.76

Table S483.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GPS2 MUTATED 2 2 6 1
GPS2 WILD-TYPE 270 175 227 275
'GPS2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.31 (Fisher's exact test), Q value = 0.93

Table S484.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GPS2 MUTATED 4 3 1 3 0 0
GPS2 WILD-TYPE 271 133 205 131 87 120
'GPS2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.478 (Fisher's exact test), Q value = 1

Table S485.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
GPS2 MUTATED 1 0 1 1 2
GPS2 WILD-TYPE 177 120 65 91 110
'GPS2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 0.98

Table S486.  Gene #41: 'GPS2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
GPS2 MUTATED 2 3 0
GPS2 WILD-TYPE 277 178 108
'DOCK11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S487.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
DOCK11 MUTATED 0 0 3 4 1 3 0 0
DOCK11 WILD-TYPE 21 38 111 93 107 70 19 39
'DOCK11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S488.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
DOCK11 MUTATED 2 2 5 2 0
DOCK11 WILD-TYPE 94 150 111 87 56
'DOCK11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.93

Table S489.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
DOCK11 MUTATED 3 7 1 9 0
DOCK11 WILD-TYPE 244 356 85 222 36
'DOCK11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S490.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
DOCK11 MUTATED 2 3 2 3 2 0
DOCK11 WILD-TYPE 126 93 154 104 107 52
'DOCK11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 0.98

Table S491.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
DOCK11 MUTATED 5 2 1
DOCK11 WILD-TYPE 140 129 117
'DOCK11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 0.93

Table S492.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
DOCK11 MUTATED 0 0 4 0 4 0
DOCK11 WILD-TYPE 59 48 86 53 109 31
'DOCK11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.062 (Fisher's exact test), Q value = 0.6

Table S493.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
DOCK11 MUTATED 9 10 1
DOCK11 WILD-TYPE 496 269 189
'DOCK11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0251 (Fisher's exact test), Q value = 0.39

Table S494.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
DOCK11 MUTATED 2 7 0 4 4 3
DOCK11 WILD-TYPE 261 144 79 257 164 49

Figure S109.  Get High-res Image Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'DOCK11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0914 (Fisher's exact test), Q value = 0.69

Table S495.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
DOCK11 MUTATED 9 2 7 2
DOCK11 WILD-TYPE 263 175 226 274
'DOCK11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0457 (Fisher's exact test), Q value = 0.53

Table S496.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
DOCK11 MUTATED 7 8 2 1 1 1
DOCK11 WILD-TYPE 268 128 204 133 86 119

Figure S110.  Get High-res Image Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'DOCK11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0382 (Fisher's exact test), Q value = 0.49

Table S497.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
DOCK11 MUTATED 2 6 0 0 4
DOCK11 WILD-TYPE 176 114 66 92 108

Figure S111.  Get High-res Image Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'DOCK11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 0.75

Table S498.  Gene #42: 'DOCK11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
DOCK11 MUTATED 9 3 0
DOCK11 WILD-TYPE 270 178 108
'HRNR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.988 (Fisher's exact test), Q value = 1

Table S499.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
HRNR MUTATED 0 1 5 5 4 4 0 1
HRNR WILD-TYPE 21 37 109 92 104 69 19 38
'HRNR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S500.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
HRNR MUTATED 2 7 4 5 2
HRNR WILD-TYPE 94 145 112 84 54
'HRNR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 0.96

Table S501.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
HRNR MUTATED 5 12 5 7 2
HRNR WILD-TYPE 242 351 81 224 34
'HRNR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S502.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
HRNR MUTATED 3 2 6 3 4 2
HRNR WILD-TYPE 125 94 150 104 105 50
'HRNR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S503.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
HRNR MUTATED 4 6 6
HRNR WILD-TYPE 141 125 112
'HRNR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S504.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
HRNR MUTATED 2 0 3 3 6 2
HRNR WILD-TYPE 57 48 87 50 107 29
'HRNR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.491 (Fisher's exact test), Q value = 1

Table S505.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
HRNR MUTATED 13 11 7
HRNR WILD-TYPE 492 268 183
'HRNR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S506.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
HRNR MUTATED 8 3 3 7 7 3
HRNR WILD-TYPE 255 148 76 254 161 49
'HRNR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S507.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
HRNR MUTATED 11 3 7 9
HRNR WILD-TYPE 261 174 226 267
'HRNR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S508.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
HRNR MUTATED 6 7 4 6 5 2
HRNR WILD-TYPE 269 129 202 128 82 118
'HRNR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.77

Table S509.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
HRNR MUTATED 6 4 0 0 5
HRNR WILD-TYPE 172 116 66 92 107
'HRNR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S510.  Gene #43: 'HRNR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
HRNR MUTATED 9 4 2
HRNR WILD-TYPE 270 177 106
'CASZ1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S511.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CASZ1 MUTATED 0 1 1 2 2 1 0 0
CASZ1 WILD-TYPE 21 37 113 95 106 72 19 39
'CASZ1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S512.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CASZ1 MUTATED 1 3 1 2 0
CASZ1 WILD-TYPE 95 149 115 87 56
'CASZ1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S513.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CASZ1 MUTATED 5 4 1 3 0
CASZ1 WILD-TYPE 242 359 85 228 36
'CASZ1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.867 (Fisher's exact test), Q value = 1

Table S514.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CASZ1 MUTATED 2 2 2 1 3 0
CASZ1 WILD-TYPE 126 94 154 106 106 52
'CASZ1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 0.75

Table S515.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CASZ1 MUTATED 1 0 3
CASZ1 WILD-TYPE 144 131 115
'CASZ1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.934 (Fisher's exact test), Q value = 1

Table S516.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CASZ1 MUTATED 0 0 1 1 2 0
CASZ1 WILD-TYPE 59 48 89 52 111 31
'CASZ1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S517.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CASZ1 MUTATED 7 5 2
CASZ1 WILD-TYPE 498 274 188
'CASZ1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S518.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CASZ1 MUTATED 2 2 1 5 4 0
CASZ1 WILD-TYPE 261 149 78 256 164 52
'CASZ1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S519.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CASZ1 MUTATED 2 3 5 3
CASZ1 WILD-TYPE 270 174 228 273
'CASZ1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S520.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CASZ1 MUTATED 5 1 3 1 0 3
CASZ1 WILD-TYPE 270 135 203 133 87 117
'CASZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.429 (Fisher's exact test), Q value = 0.98

Table S521.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CASZ1 MUTATED 4 1 0 0 3
CASZ1 WILD-TYPE 174 119 66 92 109
'CASZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.326 (Fisher's exact test), Q value = 0.94

Table S522.  Gene #44: 'CASZ1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CASZ1 MUTATED 6 2 0
CASZ1 WILD-TYPE 273 179 108
'CDC42EP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.521 (Fisher's exact test), Q value = 1

Table S523.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CDC42EP1 MUTATED 0 0 1 2 0 0 0 1
CDC42EP1 WILD-TYPE 21 38 113 95 108 73 19 38
'CDC42EP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.463 (Fisher's exact test), Q value = 1

Table S524.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CDC42EP1 MUTATED 1 1 0 2 0
CDC42EP1 WILD-TYPE 95 151 116 87 56
'CDC42EP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 0.98

Table S525.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CDC42EP1 MUTATED 0 2 1 2 0
CDC42EP1 WILD-TYPE 247 361 85 229 36
'CDC42EP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.424 (Fisher's exact test), Q value = 0.98

Table S526.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CDC42EP1 MUTATED 0 0 1 2 0 0
CDC42EP1 WILD-TYPE 128 96 155 105 109 52
'CDC42EP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S527.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CDC42EP1 MUTATED 1 2 1
CDC42EP1 WILD-TYPE 144 129 117
'CDC42EP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S528.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CDC42EP1 MUTATED 1 0 2 1 0 0
CDC42EP1 WILD-TYPE 58 48 88 52 113 31
'CDC42EP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S529.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CDC42EP1 MUTATED 2 2 1
CDC42EP1 WILD-TYPE 503 277 189
'CDC42EP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S530.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CDC42EP1 MUTATED 1 0 1 1 2 0
CDC42EP1 WILD-TYPE 262 151 78 260 166 52
'CDC42EP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S531.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CDC42EP1 MUTATED 2 0 2 1
CDC42EP1 WILD-TYPE 270 177 231 275
'CDC42EP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.305 (Fisher's exact test), Q value = 0.93

Table S532.  Gene #45: 'CDC42EP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CDC42EP1 MUTATED 0 2 1 1 0 1
CDC42EP1 WILD-TYPE 275 134 205 133 87 119
'C1QTNF5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S533.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
C1QTNF5 MUTATED 0 0 2 0 0 1 0 0
C1QTNF5 WILD-TYPE 21 38 112 97 108 72 19 39
'C1QTNF5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.2 (Fisher's exact test), Q value = 0.86

Table S534.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
C1QTNF5 MUTATED 2 0 1 0 0
C1QTNF5 WILD-TYPE 94 152 115 89 56
'C1QTNF5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.93

Table S535.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
C1QTNF5 MUTATED 2 1 2 2 0
C1QTNF5 WILD-TYPE 245 362 84 229 36
'C1QTNF5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S536.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
C1QTNF5 MUTATED 1 1 1
C1QTNF5 WILD-TYPE 144 130 117
'C1QTNF5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S537.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
C1QTNF5 MUTATED 1 0 1 1 0 0
C1QTNF5 WILD-TYPE 58 48 89 52 113 31
'C1QTNF5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S538.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
C1QTNF5 MUTATED 3 2 2
C1QTNF5 WILD-TYPE 502 277 188
'C1QTNF5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.338 (Fisher's exact test), Q value = 0.95

Table S539.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
C1QTNF5 MUTATED 2 2 1 1 0 1
C1QTNF5 WILD-TYPE 261 149 78 260 168 51
'C1QTNF5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S540.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
C1QTNF5 MUTATED 2 1 3 1
C1QTNF5 WILD-TYPE 270 176 230 275
'C1QTNF5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.084 (Fisher's exact test), Q value = 0.68

Table S541.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
C1QTNF5 MUTATED 0 2 4 1 0 0
C1QTNF5 WILD-TYPE 275 134 202 133 87 120
'C1QTNF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0137 (Fisher's exact test), Q value = 0.26

Table S542.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
C1QTNF5 MUTATED 0 0 2 2 0
C1QTNF5 WILD-TYPE 178 120 64 90 112

Figure S112.  Get High-res Image Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

'C1QTNF5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0796 (Fisher's exact test), Q value = 0.67

Table S543.  Gene #46: 'C1QTNF5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
C1QTNF5 MUTATED 0 3 1
C1QTNF5 WILD-TYPE 279 178 107
'TGS1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S544.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TGS1 MUTATED 1 0 1 1 1 2 0 0
TGS1 WILD-TYPE 20 38 113 96 107 71 19 39
'TGS1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S545.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TGS1 MUTATED 1 1 3 1 0
TGS1 WILD-TYPE 95 151 113 88 56
'TGS1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.42 (Fisher's exact test), Q value = 0.98

Table S546.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TGS1 MUTATED 2 7 0 2 1
TGS1 WILD-TYPE 245 356 86 229 35
'TGS1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 0.93

Table S547.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TGS1 MUTATED 1 3 4 3 0 0
TGS1 WILD-TYPE 127 93 152 104 109 52
'TGS1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 0.75

Table S548.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TGS1 MUTATED 1 0 3
TGS1 WILD-TYPE 144 131 115
'TGS1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S549.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TGS1 MUTATED 0 1 1 0 1 1
TGS1 WILD-TYPE 59 47 89 53 112 30
'TGS1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S550.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TGS1 MUTATED 7 4 2
TGS1 WILD-TYPE 498 275 188
'TGS1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.246 (Fisher's exact test), Q value = 0.91

Table S551.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TGS1 MUTATED 2 5 0 4 1 1
TGS1 WILD-TYPE 261 146 79 257 167 51
'TGS1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.93

Table S552.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TGS1 MUTATED 1 2 4 6
TGS1 WILD-TYPE 271 175 229 270
'TGS1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S553.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TGS1 MUTATED 5 1 5 2 0 0
TGS1 WILD-TYPE 270 135 201 132 87 120
'TGS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 0.91

Table S554.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TGS1 MUTATED 3 0 2 0 2
TGS1 WILD-TYPE 175 120 64 92 110
'TGS1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 0.96

Table S555.  Gene #47: 'TGS1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TGS1 MUTATED 2 4 1
TGS1 WILD-TYPE 277 177 107
'USP36 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S556.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
USP36 MUTATED 0 0 2 3 2 0 0 0
USP36 WILD-TYPE 21 38 112 94 106 73 19 39
'USP36 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 0.84

Table S557.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
USP36 MUTATED 2 1 0 3 1
USP36 WILD-TYPE 94 151 116 86 55
'USP36 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.968 (Fisher's exact test), Q value = 1

Table S558.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
USP36 MUTATED 2 3 1 2 0
USP36 WILD-TYPE 245 360 85 229 36
'USP36 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S559.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
USP36 MUTATED 0 1 1 0 1 0
USP36 WILD-TYPE 128 95 155 107 108 52
'USP36 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.712 (Fisher's exact test), Q value = 1

Table S560.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
USP36 MUTATED 3 3 1
USP36 WILD-TYPE 142 128 117
'USP36 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S561.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
USP36 MUTATED 1 0 3 0 3 0
USP36 WILD-TYPE 58 48 87 53 110 31
'USP36 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S562.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
USP36 MUTATED 5 3 0
USP36 WILD-TYPE 500 276 190
'USP36 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0769 (Fisher's exact test), Q value = 0.66

Table S563.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
USP36 MUTATED 5 0 0 0 3 0
USP36 WILD-TYPE 258 151 79 261 165 52
'USP36 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S564.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
USP36 MUTATED 3 1 3 1
USP36 WILD-TYPE 269 176 230 275
'USP36 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.347 (Fisher's exact test), Q value = 0.96

Table S565.  Gene #48: 'USP36 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
USP36 MUTATED 2 0 1 1 1 3
USP36 WILD-TYPE 273 136 205 133 86 117
'ASB10 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.944 (Fisher's exact test), Q value = 1

Table S566.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ASB10 MUTATED 0 0 1 1 2 0 0 0
ASB10 WILD-TYPE 21 38 113 96 106 73 19 39
'ASB10 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0643 (Fisher's exact test), Q value = 0.61

Table S567.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ASB10 MUTATED 1 0 1 0 2
ASB10 WILD-TYPE 95 152 115 89 54
'ASB10 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S568.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ASB10 MUTATED 2 3 1 2 0
ASB10 WILD-TYPE 245 360 85 229 36
'ASB10 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S569.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ASB10 MUTATED 1 1 3 0 2 1
ASB10 WILD-TYPE 127 95 153 107 107 51
'ASB10 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S570.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ASB10 MUTATED 5 3 0
ASB10 WILD-TYPE 500 276 190
'ASB10 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S571.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ASB10 MUTATED 3 3 0 1 1 0
ASB10 WILD-TYPE 260 148 79 260 167 52
'ASB10 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S572.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ASB10 MUTATED 2 0 2 4
ASB10 WILD-TYPE 270 177 231 272
'ASB10 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 0.93

Table S573.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ASB10 MUTATED 5 1 0 1 1 0
ASB10 WILD-TYPE 270 135 206 133 86 120
'ASB10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S574.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ASB10 MUTATED 1 2 0 1 1
ASB10 WILD-TYPE 177 118 66 91 111
'ASB10 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S575.  Gene #49: 'ASB10 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ASB10 MUTATED 3 1 1
ASB10 WILD-TYPE 276 180 107
'EIF4A2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 0.88

Table S576.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
EIF4A2 MUTATED 1 0 1 0 0 1 0 0
EIF4A2 WILD-TYPE 20 38 113 97 108 72 19 39
'EIF4A2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S577.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
EIF4A2 MUTATED 1 1 1 0 0
EIF4A2 WILD-TYPE 95 151 115 89 56
'EIF4A2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.881 (Fisher's exact test), Q value = 1

Table S578.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
EIF4A2 MUTATED 2 5 0 2 0
EIF4A2 WILD-TYPE 245 358 86 229 36
'EIF4A2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.565 (Fisher's exact test), Q value = 1

Table S579.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
EIF4A2 MUTATED 2 1 0 2 1 0
EIF4A2 WILD-TYPE 126 95 156 105 108 52
'EIF4A2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S580.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
EIF4A2 MUTATED 1 1 1
EIF4A2 WILD-TYPE 144 130 117
'EIF4A2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.369 (Fisher's exact test), Q value = 0.98

Table S581.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
EIF4A2 MUTATED 1 0 0 0 1 1
EIF4A2 WILD-TYPE 58 48 90 53 112 30
'EIF4A2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.227 (Fisher's exact test), Q value = 0.88

Table S582.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
EIF4A2 MUTATED 3 5 1
EIF4A2 WILD-TYPE 502 274 189
'EIF4A2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.084 (Fisher's exact test), Q value = 0.68

Table S583.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
EIF4A2 MUTATED 2 1 0 2 1 3
EIF4A2 WILD-TYPE 261 150 79 259 167 49
'EIF4A2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.26 (Fisher's exact test), Q value = 0.92

Table S584.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
EIF4A2 MUTATED 3 3 0 3
EIF4A2 WILD-TYPE 269 174 233 273
'EIF4A2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S585.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
EIF4A2 MUTATED 4 2 1 1 0 1
EIF4A2 WILD-TYPE 271 134 205 133 87 119
'EIF4A2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.372 (Fisher's exact test), Q value = 0.98

Table S586.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
EIF4A2 MUTATED 1 1 1 0 3
EIF4A2 WILD-TYPE 177 119 65 92 109
'EIF4A2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.93

Table S587.  Gene #50: 'EIF4A2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
EIF4A2 MUTATED 2 4 0
EIF4A2 WILD-TYPE 277 177 108
'DNAH12 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S588.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
DNAH12 MUTATED 0 0 2 2 2 1 0 1
DNAH12 WILD-TYPE 21 38 112 95 106 72 19 38
'DNAH12 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S589.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
DNAH12 MUTATED 1 4 1 2 0
DNAH12 WILD-TYPE 95 148 115 87 56
'DNAH12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S590.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
DNAH12 MUTATED 4 9 1 3 0
DNAH12 WILD-TYPE 243 354 85 228 36
'DNAH12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S591.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
DNAH12 MUTATED 2 2 5 3 1 0
DNAH12 WILD-TYPE 126 94 151 104 108 52
'DNAH12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S592.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
DNAH12 MUTATED 1 1 3
DNAH12 WILD-TYPE 144 130 115
'DNAH12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S593.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
DNAH12 MUTATED 1 0 2 1 1 0
DNAH12 WILD-TYPE 58 48 88 52 112 31
'DNAH12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S594.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
DNAH12 MUTATED 10 5 3
DNAH12 WILD-TYPE 495 274 187
'DNAH12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S595.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
DNAH12 MUTATED 3 2 1 8 4 0
DNAH12 WILD-TYPE 260 149 78 253 164 52
'DNAH12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 0.91

Table S596.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
DNAH12 MUTATED 5 4 7 2
DNAH12 WILD-TYPE 267 173 226 274
'DNAH12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S597.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
DNAH12 MUTATED 5 3 6 1 2 1
DNAH12 WILD-TYPE 270 133 200 133 85 119
'DNAH12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.16 (Fisher's exact test), Q value = 0.78

Table S598.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
DNAH12 MUTATED 3 2 0 0 5
DNAH12 WILD-TYPE 175 118 66 92 107
'DNAH12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 0.88

Table S599.  Gene #51: 'DNAH12 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
DNAH12 MUTATED 5 5 0
DNAH12 WILD-TYPE 274 176 108
'RHBG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S600.  Gene #52: 'RHBG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RHBG MUTATED 2 1 0 1 0
RHBG WILD-TYPE 245 362 86 230 36
'RHBG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00765 (Fisher's exact test), Q value = 0.17

Table S601.  Gene #52: 'RHBG MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RHBG MUTATED 0 4 0
RHBG WILD-TYPE 505 275 190

Figure S113.  Get High-res Image Gene #52: 'RHBG MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'RHBG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.108 (Fisher's exact test), Q value = 0.75

Table S602.  Gene #52: 'RHBG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RHBG MUTATED 0 2 0 0 2 0
RHBG WILD-TYPE 263 149 79 261 166 52
'RHBG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S603.  Gene #52: 'RHBG MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RHBG MUTATED 2 0 0 2
RHBG WILD-TYPE 270 177 233 274
'RHBG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.266 (Fisher's exact test), Q value = 0.93

Table S604.  Gene #52: 'RHBG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RHBG MUTATED 2 0 0 0 0 2
RHBG WILD-TYPE 273 136 206 134 87 118
'ZNF362 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S605.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ZNF362 MUTATED 0 0 2 0 2 1 0 0
ZNF362 WILD-TYPE 21 38 112 97 106 72 19 39
'ZNF362 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S606.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ZNF362 MUTATED 1 2 1 0 1
ZNF362 WILD-TYPE 95 150 115 89 55
'ZNF362 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0916 (Fisher's exact test), Q value = 0.69

Table S607.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ZNF362 MUTATED 0 1 1 1 1
ZNF362 WILD-TYPE 247 362 85 230 35
'ZNF362 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.155 (Fisher's exact test), Q value = 0.78

Table S608.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ZNF362 MUTATED 0 3 1
ZNF362 WILD-TYPE 145 128 117
'ZNF362 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S609.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ZNF362 MUTATED 1 1 0 0 2 0
ZNF362 WILD-TYPE 58 47 90 53 111 31
'ZNF362 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 0.98

Table S610.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ZNF362 MUTATED 4 0 1
ZNF362 WILD-TYPE 501 279 189
'ZNF362 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.91 (Fisher's exact test), Q value = 1

Table S611.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ZNF362 MUTATED 2 1 0 2 0 0
ZNF362 WILD-TYPE 261 150 79 259 168 52
'ZNF362 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.083 (Fisher's exact test), Q value = 0.68

Table S612.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ZNF362 MUTATED 0 0 1 4
ZNF362 WILD-TYPE 272 177 232 272
'ZNF362 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.414 (Fisher's exact test), Q value = 0.98

Table S613.  Gene #53: 'ZNF362 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ZNF362 MUTATED 1 0 1 2 1 0
ZNF362 WILD-TYPE 274 136 205 132 86 120
'FXYD5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.568 (Fisher's exact test), Q value = 1

Table S614.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
FXYD5 MUTATED 0 1 1 1 0 0 0 0
FXYD5 WILD-TYPE 21 37 113 96 108 73 19 39
'FXYD5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S615.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
FXYD5 MUTATED 1 1 0 1 0
FXYD5 WILD-TYPE 95 151 116 88 56
'FXYD5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S616.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
FXYD5 MUTATED 0 4 0 1 0
FXYD5 WILD-TYPE 247 359 86 230 36
'FXYD5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S617.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
FXYD5 MUTATED 2 0 1
FXYD5 WILD-TYPE 143 131 117
'FXYD5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S618.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
FXYD5 MUTATED 0 0 1 1 1 0
FXYD5 WILD-TYPE 59 48 89 52 112 31
'FXYD5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0874 (Fisher's exact test), Q value = 0.68

Table S619.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
FXYD5 MUTATED 1 1 3
FXYD5 WILD-TYPE 504 278 187
'FXYD5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.122 (Fisher's exact test), Q value = 0.75

Table S620.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
FXYD5 MUTATED 0 1 2 1 1 0
FXYD5 WILD-TYPE 263 150 77 260 167 52
'FXYD5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S621.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
FXYD5 MUTATED 1 2 1 1
FXYD5 WILD-TYPE 271 175 232 275
'FXYD5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S622.  Gene #54: 'FXYD5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
FXYD5 MUTATED 1 1 3 0 0 0
FXYD5 WILD-TYPE 274 135 203 134 87 120
'BCORL1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.151 (Fisher's exact test), Q value = 0.78

Table S623.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
BCORL1 MUTATED 0 3 2 2 0 1 0 0
BCORL1 WILD-TYPE 21 35 112 95 108 72 19 39
'BCORL1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S624.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
BCORL1 MUTATED 2 3 1 2 0
BCORL1 WILD-TYPE 94 149 115 87 56
'BCORL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.66 (Fisher's exact test), Q value = 1

Table S625.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
BCORL1 MUTATED 6 5 0 4 0
BCORL1 WILD-TYPE 241 358 86 227 36
'BCORL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.736 (Fisher's exact test), Q value = 1

Table S626.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
BCORL1 MUTATED 2 2 3 0 2 0
BCORL1 WILD-TYPE 126 94 153 107 107 52
'BCORL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 0.93

Table S627.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
BCORL1 MUTATED 3 3 0
BCORL1 WILD-TYPE 142 128 118
'BCORL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0292 (Fisher's exact test), Q value = 0.4

Table S628.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
BCORL1 MUTATED 0 0 1 0 2 3
BCORL1 WILD-TYPE 59 48 89 53 111 28

Figure S114.  Get High-res Image Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'BCORL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.75

Table S629.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
BCORL1 MUTATED 6 8 1
BCORL1 WILD-TYPE 499 271 189
'BCORL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.819 (Fisher's exact test), Q value = 1

Table S630.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
BCORL1 MUTATED 3 3 1 3 4 1
BCORL1 WILD-TYPE 260 148 78 258 164 51
'BCORL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S631.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
BCORL1 MUTATED 7 2 3 3
BCORL1 WILD-TYPE 265 175 230 273
'BCORL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S632.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
BCORL1 MUTATED 3 3 3 2 1 3
BCORL1 WILD-TYPE 272 133 203 132 86 117
'BCORL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S633.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
BCORL1 MUTATED 4 3 0 2 2
BCORL1 WILD-TYPE 174 117 66 90 110
'BCORL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S634.  Gene #55: 'BCORL1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
BCORL1 MUTATED 7 2 2
BCORL1 WILD-TYPE 272 179 106
'PTHLH MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.229 (Fisher's exact test), Q value = 0.88

Table S635.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PTHLH MUTATED 0 1 0 0 1 2 0 1
PTHLH WILD-TYPE 21 37 114 97 107 71 19 38
'PTHLH MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S636.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PTHLH MUTATED 1 2 2 0 0
PTHLH WILD-TYPE 95 150 114 89 56
'PTHLH MUTATION STATUS' versus 'CN_CNMF'

P value = 0.039 (Fisher's exact test), Q value = 0.5

Table S637.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PTHLH MUTATED 2 1 1 1 2
PTHLH WILD-TYPE 245 362 85 230 34

Figure S115.  Get High-res Image Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'PTHLH MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0205 (Fisher's exact test), Q value = 0.34

Table S638.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PTHLH MUTATED 0 3 0 0 1 1
PTHLH WILD-TYPE 128 93 156 107 108 51

Figure S116.  Get High-res Image Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'PTHLH MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S639.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PTHLH MUTATED 1 1 2
PTHLH WILD-TYPE 144 130 116
'PTHLH MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.576 (Fisher's exact test), Q value = 1

Table S640.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PTHLH MUTATED 0 1 0 1 2 0
PTHLH WILD-TYPE 59 47 90 52 111 31
'PTHLH MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.76

Table S641.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PTHLH MUTATED 6 0 1
PTHLH WILD-TYPE 499 279 189
'PTHLH MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.654 (Fisher's exact test), Q value = 1

Table S642.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PTHLH MUTATED 4 1 0 2 0 0
PTHLH WILD-TYPE 259 150 79 259 168 52
'PTHLH MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S643.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PTHLH MUTATED 2 1 1 2
PTHLH WILD-TYPE 270 176 232 274
'PTHLH MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S644.  Gene #56: 'PTHLH MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PTHLH MUTATED 4 0 0 2 0 0
PTHLH WILD-TYPE 271 136 206 132 87 120
'PIK3R1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.148 (Fisher's exact test), Q value = 0.77

Table S645.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PIK3R1 MUTATED 0 0 1 1 1 5 0 0
PIK3R1 WILD-TYPE 21 38 113 96 107 68 19 39
'PIK3R1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.84

Table S646.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PIK3R1 MUTATED 1 1 5 1 0
PIK3R1 WILD-TYPE 95 151 111 88 56
'PIK3R1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 0.98

Table S647.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PIK3R1 MUTATED 5 3 2 4 1
PIK3R1 WILD-TYPE 242 360 84 227 35
'PIK3R1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0673 (Fisher's exact test), Q value = 0.62

Table S648.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PIK3R1 MUTATED 0 3 1 0 3 0
PIK3R1 WILD-TYPE 128 93 155 107 106 52
'PIK3R1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.63 (Fisher's exact test), Q value = 1

Table S649.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PIK3R1 MUTATED 3 1 1
PIK3R1 WILD-TYPE 142 130 117
'PIK3R1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0495 (Fisher's exact test), Q value = 0.56

Table S650.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PIK3R1 MUTATED 0 0 0 0 3 2
PIK3R1 WILD-TYPE 59 48 90 53 110 29

Figure S117.  Get High-res Image Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 0.72

Table S651.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PIK3R1 MUTATED 9 6 0
PIK3R1 WILD-TYPE 496 273 190
'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.159 (Fisher's exact test), Q value = 0.78

Table S652.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PIK3R1 MUTATED 2 6 0 3 3 1
PIK3R1 WILD-TYPE 261 145 79 258 165 51
'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.75

Table S653.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PIK3R1 MUTATED 3 0 4 7
PIK3R1 WILD-TYPE 269 177 229 269
'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.395 (Fisher's exact test), Q value = 0.98

Table S654.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PIK3R1 MUTATED 4 1 1 4 1 3
PIK3R1 WILD-TYPE 271 135 205 130 86 117
'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.75

Table S655.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
PIK3R1 MUTATED 3 4 2 0 0
PIK3R1 WILD-TYPE 175 116 64 92 112
'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S656.  Gene #57: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
PIK3R1 MUTATED 6 2 1
PIK3R1 WILD-TYPE 273 179 107
'ZNF687 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.96

Table S657.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ZNF687 MUTATED 0 2 2 4 1 0 0 0
ZNF687 WILD-TYPE 21 36 112 93 107 73 19 39
'ZNF687 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.129 (Fisher's exact test), Q value = 0.75

Table S658.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ZNF687 MUTATED 2 3 0 4 0
ZNF687 WILD-TYPE 94 149 116 85 56
'ZNF687 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.88

Table S659.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ZNF687 MUTATED 3 2 0 6 0
ZNF687 WILD-TYPE 244 361 86 225 36
'ZNF687 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.75

Table S660.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ZNF687 MUTATED 2 0 1 0 4 0
ZNF687 WILD-TYPE 126 96 155 107 105 52
'ZNF687 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.75

Table S661.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ZNF687 MUTATED 6 1 1
ZNF687 WILD-TYPE 139 130 117
'ZNF687 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.305 (Fisher's exact test), Q value = 0.93

Table S662.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ZNF687 MUTATED 0 0 4 0 3 1
ZNF687 WILD-TYPE 59 48 86 53 110 30
'ZNF687 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S663.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ZNF687 MUTATED 4 6 1
ZNF687 WILD-TYPE 501 273 189
'ZNF687 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.25 (Fisher's exact test), Q value = 0.91

Table S664.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ZNF687 MUTATED 3 1 1 1 5 0
ZNF687 WILD-TYPE 260 150 78 260 163 52
'ZNF687 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S665.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ZNF687 MUTATED 6 0 2 3
ZNF687 WILD-TYPE 266 177 231 273
'ZNF687 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0181 (Fisher's exact test), Q value = 0.31

Table S666.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ZNF687 MUTATED 5 0 1 0 0 5
ZNF687 WILD-TYPE 270 136 205 134 87 115

Figure S118.  Get High-res Image Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'ZNF687 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S667.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ZNF687 MUTATED 2 2 0 0 1
ZNF687 WILD-TYPE 176 118 66 92 111
'ZNF687 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S668.  Gene #58: 'ZNF687 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ZNF687 MUTATED 4 1 0
ZNF687 WILD-TYPE 275 180 108
'GPRIN2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S669.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
GPRIN2 MUTATED 0 1 0 2 3 1 0 0
GPRIN2 WILD-TYPE 21 37 114 95 105 72 19 39
'GPRIN2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S670.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
GPRIN2 MUTATED 0 3 1 2 1
GPRIN2 WILD-TYPE 96 149 115 87 55
'GPRIN2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.981 (Fisher's exact test), Q value = 1

Table S671.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GPRIN2 MUTATED 3 5 1 2 0
GPRIN2 WILD-TYPE 244 358 85 229 36
'GPRIN2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.706 (Fisher's exact test), Q value = 1

Table S672.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
GPRIN2 MUTATED 1 2 2 0 2 0
GPRIN2 WILD-TYPE 127 94 154 107 107 52
'GPRIN2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S673.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
GPRIN2 MUTATED 3 2 1
GPRIN2 WILD-TYPE 142 129 117
'GPRIN2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.77

Table S674.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
GPRIN2 MUTATED 2 0 1 0 1 2
GPRIN2 WILD-TYPE 57 48 89 53 112 29
'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S675.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GPRIN2 MUTATED 5 5 1
GPRIN2 WILD-TYPE 500 274 189
'GPRIN2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.421 (Fisher's exact test), Q value = 0.98

Table S676.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GPRIN2 MUTATED 1 2 0 4 4 0
GPRIN2 WILD-TYPE 262 149 79 257 164 52
'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.372 (Fisher's exact test), Q value = 0.98

Table S677.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GPRIN2 MUTATED 4 1 4 1
GPRIN2 WILD-TYPE 268 176 229 275
'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0633 (Fisher's exact test), Q value = 0.6

Table S678.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GPRIN2 MUTATED 2 0 1 3 0 4
GPRIN2 WILD-TYPE 273 136 205 131 87 116
'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 0.98

Table S679.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
GPRIN2 MUTATED 1 3 1 0 1
GPRIN2 WILD-TYPE 177 117 65 92 111
'GPRIN2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S680.  Gene #59: 'GPRIN2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
GPRIN2 MUTATED 4 2 0
GPRIN2 WILD-TYPE 275 179 108
'ANKRD12 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.93

Table S681.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ANKRD12 MUTATED 0 1 6 0 2 1 0 0
ANKRD12 WILD-TYPE 21 37 108 97 106 72 19 39
'ANKRD12 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.134 (Fisher's exact test), Q value = 0.76

Table S682.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ANKRD12 MUTATED 4 5 1 0 0
ANKRD12 WILD-TYPE 92 147 115 89 56
'ANKRD12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S683.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ANKRD12 MUTATED 3 6 3 5 0
ANKRD12 WILD-TYPE 244 357 83 226 36
'ANKRD12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S684.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ANKRD12 MUTATED 2 3 2 2 1 1
ANKRD12 WILD-TYPE 126 93 154 105 108 51
'ANKRD12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.386 (Fisher's exact test), Q value = 0.98

Table S685.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ANKRD12 MUTATED 4 1 1
ANKRD12 WILD-TYPE 141 130 117
'ANKRD12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0674 (Fisher's exact test), Q value = 0.62

Table S686.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ANKRD12 MUTATED 0 0 0 0 5 1
ANKRD12 WILD-TYPE 59 48 90 53 108 30
'ANKRD12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.409 (Fisher's exact test), Q value = 0.98

Table S687.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ANKRD12 MUTATED 10 3 5
ANKRD12 WILD-TYPE 495 276 185
'ANKRD12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0631 (Fisher's exact test), Q value = 0.6

Table S688.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ANKRD12 MUTATED 3 2 0 11 1 1
ANKRD12 WILD-TYPE 260 149 79 250 167 51
'ANKRD12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.86

Table S689.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ANKRD12 MUTATED 3 1 6 8
ANKRD12 WILD-TYPE 269 176 227 268
'ANKRD12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.948 (Fisher's exact test), Q value = 1

Table S690.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ANKRD12 MUTATED 6 3 5 2 1 1
ANKRD12 WILD-TYPE 269 133 201 132 86 119
'ANKRD12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.86

Table S691.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ANKRD12 MUTATED 3 1 3 0 1
ANKRD12 WILD-TYPE 175 119 63 92 111
'ANKRD12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S692.  Gene #60: 'ANKRD12 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ANKRD12 MUTATED 3 3 2
ANKRD12 WILD-TYPE 276 178 106
'PAX2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S693.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PAX2 MUTATED 0 0 1 0 1 1 0 0
PAX2 WILD-TYPE 21 38 113 97 107 72 19 39
'PAX2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.334 (Fisher's exact test), Q value = 0.95

Table S694.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PAX2 MUTATED 1 0 1 0 1
PAX2 WILD-TYPE 95 152 115 89 55
'PAX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S695.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PAX2 MUTATED 0 1 0 3 0
PAX2 WILD-TYPE 247 362 86 228 36
'PAX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.98

Table S696.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PAX2 MUTATED 0 2 1
PAX2 WILD-TYPE 145 129 117
'PAX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0564 (Fisher's exact test), Q value = 0.59

Table S697.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PAX2 MUTATED 1 2 0 0 0 0
PAX2 WILD-TYPE 58 46 90 53 113 31
'PAX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.93

Table S698.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PAX2 MUTATED 4 0 0
PAX2 WILD-TYPE 501 279 190
'PAX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.286 (Fisher's exact test), Q value = 0.93

Table S699.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PAX2 MUTATED 2 2 0 0 0 0
PAX2 WILD-TYPE 261 149 79 261 168 52
'PAX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S700.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PAX2 MUTATED 1 0 2 1
PAX2 WILD-TYPE 271 177 231 275
'PAX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S701.  Gene #61: 'PAX2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PAX2 MUTATED 2 0 0 1 1 0
PAX2 WILD-TYPE 273 136 206 133 86 120
'KCNN3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.77

Table S702.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
KCNN3 MUTATED 1 0 0 2 0 1 0 1
KCNN3 WILD-TYPE 20 38 114 95 108 72 19 38
'KCNN3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S703.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
KCNN3 MUTATED 0 1 2 2 0
KCNN3 WILD-TYPE 96 151 114 87 56
'KCNN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 0.91

Table S704.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
KCNN3 MUTATED 4 1 0 4 0
KCNN3 WILD-TYPE 243 362 86 227 36
'KCNN3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 0.76

Table S705.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
KCNN3 MUTATED 2 0 0 0 2 1
KCNN3 WILD-TYPE 126 96 156 107 107 51
'KCNN3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.27 (Fisher's exact test), Q value = 0.93

Table S706.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
KCNN3 MUTATED 3 0 1
KCNN3 WILD-TYPE 142 131 117
'KCNN3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S707.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
KCNN3 MUTATED 0 0 2 1 1 0
KCNN3 WILD-TYPE 59 48 88 52 112 31
'KCNN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S708.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
KCNN3 MUTATED 5 4 0
KCNN3 WILD-TYPE 500 275 190
'KCNN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.401 (Fisher's exact test), Q value = 0.98

Table S709.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
KCNN3 MUTATED 1 3 0 2 2 1
KCNN3 WILD-TYPE 262 148 79 259 166 51
'KCNN3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.93

Table S710.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
KCNN3 MUTATED 4 0 1 4
KCNN3 WILD-TYPE 268 177 232 272
'KCNN3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S711.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
KCNN3 MUTATED 3 3 1 1 0 1
KCNN3 WILD-TYPE 272 133 205 133 87 119
'KCNN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S712.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
KCNN3 MUTATED 2 2 0 0 0
KCNN3 WILD-TYPE 176 118 66 92 112
'KCNN3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.414 (Fisher's exact test), Q value = 0.98

Table S713.  Gene #62: 'KCNN3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
KCNN3 MUTATED 3 0 1
KCNN3 WILD-TYPE 276 181 107
'ICOSLG MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S714.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ICOSLG MUTATED 0 0 2 1 0 0 0 0
ICOSLG WILD-TYPE 21 38 112 96 108 73 19 39
'ICOSLG MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.129 (Fisher's exact test), Q value = 0.75

Table S715.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ICOSLG MUTATED 2 0 0 1 0
ICOSLG WILD-TYPE 94 152 116 88 56
'ICOSLG MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0409 (Fisher's exact test), Q value = 0.5

Table S716.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ICOSLG MUTATED 1 0 1 2 1
ICOSLG WILD-TYPE 246 363 85 229 35

Figure S119.  Get High-res Image Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'ICOSLG MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.289 (Fisher's exact test), Q value = 0.93

Table S717.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ICOSLG MUTATED 1 2 0 0 1 0
ICOSLG WILD-TYPE 127 94 156 107 108 52
'ICOSLG MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S718.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ICOSLG MUTATED 4 1 0
ICOSLG WILD-TYPE 501 278 190
'ICOSLG MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.969 (Fisher's exact test), Q value = 1

Table S719.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ICOSLG MUTATED 1 1 0 2 1 0
ICOSLG WILD-TYPE 262 150 79 259 167 52
'ICOSLG MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S720.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ICOSLG MUTATED 1 0 2 2
ICOSLG WILD-TYPE 271 177 231 274
'ICOSLG MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S721.  Gene #63: 'ICOSLG MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ICOSLG MUTATED 1 1 0 1 1 1
ICOSLG WILD-TYPE 274 135 206 133 86 119
'MR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.86

Table S722.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MR1 MUTATED 0 2 0 1 2 0 0 0
MR1 WILD-TYPE 21 36 114 96 106 73 19 39
'MR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.704 (Fisher's exact test), Q value = 1

Table S723.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MR1 MUTATED 0 3 1 1 0
MR1 WILD-TYPE 96 149 115 88 56
'MR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S724.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MR1 MUTATED 2 3 1 1 0
MR1 WILD-TYPE 245 360 85 230 36
'MR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.056 (Fisher's exact test), Q value = 0.59

Table S725.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MR1 MUTATED 3 0 0 0 0 0
MR1 WILD-TYPE 125 96 156 107 109 52
'MR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S726.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MR1 MUTATED 2 1 1
MR1 WILD-TYPE 143 130 117
'MR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.966 (Fisher's exact test), Q value = 1

Table S727.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MR1 MUTATED 1 0 1 1 1 0
MR1 WILD-TYPE 58 48 89 52 112 31
'MR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.27 (Fisher's exact test), Q value = 0.93

Table S728.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MR1 MUTATED 2 4 1
MR1 WILD-TYPE 503 275 189
'MR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.362 (Fisher's exact test), Q value = 0.97

Table S729.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MR1 MUTATED 0 2 1 3 1 0
MR1 WILD-TYPE 263 149 78 258 167 52
'MR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S730.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MR1 MUTATED 2 0 3 2
MR1 WILD-TYPE 270 177 230 274
'MR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.219 (Fisher's exact test), Q value = 0.88

Table S731.  Gene #64: 'MR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MR1 MUTATED 5 1 0 0 0 1
MR1 WILD-TYPE 270 135 206 134 87 119
'ZBTB7C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S732.  Gene #65: 'ZBTB7C MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ZBTB7C MUTATED 1 2 1 0 0
ZBTB7C WILD-TYPE 246 361 85 231 36
'ZBTB7C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S733.  Gene #65: 'ZBTB7C MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ZBTB7C MUTATED 0 1 1 1 0 0
ZBTB7C WILD-TYPE 128 95 155 106 109 52
'ZBTB7C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S734.  Gene #65: 'ZBTB7C MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ZBTB7C MUTATED 2 1 2
ZBTB7C WILD-TYPE 503 278 188
'ZBTB7C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S735.  Gene #65: 'ZBTB7C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ZBTB7C MUTATED 1 1 1 2 0 0
ZBTB7C WILD-TYPE 262 150 78 259 168 52
'ZBTB7C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S736.  Gene #65: 'ZBTB7C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ZBTB7C MUTATED 1 2 1 1
ZBTB7C WILD-TYPE 271 175 232 275
'ZBTB7C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S737.  Gene #65: 'ZBTB7C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ZBTB7C MUTATED 2 1 2 0 0 0
ZBTB7C WILD-TYPE 273 135 204 134 87 120
'CABYR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.814 (Fisher's exact test), Q value = 1

Table S738.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CABYR MUTATED 2 2 1 1 0
CABYR WILD-TYPE 245 361 85 230 36
'CABYR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.5 (Fisher's exact test), Q value = 1

Table S739.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CABYR MUTATED 1 2 0 1 1 0
CABYR WILD-TYPE 127 94 156 106 108 52
'CABYR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.76

Table S740.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CABYR MUTATED 2 4 0
CABYR WILD-TYPE 503 275 190
'CABYR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00666 (Fisher's exact test), Q value = 0.16

Table S741.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CABYR MUTATED 0 3 0 1 0 2
CABYR WILD-TYPE 263 148 79 260 168 50

Figure S120.  Get High-res Image Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CABYR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.93

Table S742.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CABYR MUTATED 3 0 0 2
CABYR WILD-TYPE 269 177 233 274
'CABYR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S743.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CABYR MUTATED 2 2 0 1 0 0
CABYR WILD-TYPE 273 134 206 133 87 120
'CABYR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S744.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CABYR MUTATED 2 2 0 0 1
CABYR WILD-TYPE 176 118 66 92 111
'CABYR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.93

Table S745.  Gene #66: 'CABYR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CABYR MUTATED 4 0 1
CABYR WILD-TYPE 275 181 107
'AKT2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.77

Table S746.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
AKT2 MUTATED 0 0 0 0 2 0 1 0
AKT2 WILD-TYPE 21 38 114 97 106 73 18 39
'AKT2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S747.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
AKT2 MUTATED 1 1 1 0 0
AKT2 WILD-TYPE 95 151 115 89 56
'AKT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.68 (Fisher's exact test), Q value = 1

Table S748.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
AKT2 MUTATED 2 1 1 1 0
AKT2 WILD-TYPE 245 362 85 230 36
'AKT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S749.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
AKT2 MUTATED 1 0 2 0 0 1
AKT2 WILD-TYPE 127 96 154 107 109 51
'AKT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S750.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
AKT2 MUTATED 4 1 0
AKT2 WILD-TYPE 501 278 190
'AKT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 0.75

Table S751.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
AKT2 MUTATED 0 3 0 2 0 0
AKT2 WILD-TYPE 263 148 79 259 168 52
'AKT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S752.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
AKT2 MUTATED 1 0 2 2
AKT2 WILD-TYPE 271 177 231 274
'AKT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.309 (Fisher's exact test), Q value = 0.93

Table S753.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
AKT2 MUTATED 3 0 0 2 0 0
AKT2 WILD-TYPE 272 136 206 132 87 120
'AKT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S754.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
AKT2 MUTATED 2 0 0 1 0
AKT2 WILD-TYPE 176 120 66 91 112
'AKT2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S755.  Gene #67: 'AKT2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
AKT2 MUTATED 2 0 1
AKT2 WILD-TYPE 277 181 107
'TARBP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S756.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TARBP2 MUTATED 0 1 1 2 0 1 0 0
TARBP2 WILD-TYPE 21 37 113 95 108 72 19 39
'TARBP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.958 (Fisher's exact test), Q value = 1

Table S757.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TARBP2 MUTATED 1 1 2 1 0
TARBP2 WILD-TYPE 95 151 114 88 56
'TARBP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 0.73

Table S758.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TARBP2 MUTATED 2 0 0 4 0
TARBP2 WILD-TYPE 245 363 86 227 36
'TARBP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S759.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TARBP2 MUTATED 1 1 0 0 1 0
TARBP2 WILD-TYPE 127 95 156 107 108 52
'TARBP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.8

Table S760.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TARBP2 MUTATED 4 1 0
TARBP2 WILD-TYPE 141 130 118
'TARBP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S761.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TARBP2 MUTATED 1 0 3 0 1 0
TARBP2 WILD-TYPE 58 48 87 53 112 31
'TARBP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 0.76

Table S762.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TARBP2 MUTATED 2 4 0
TARBP2 WILD-TYPE 503 275 190
'TARBP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S763.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TARBP2 MUTATED 1 0 0 2 2 1
TARBP2 WILD-TYPE 262 151 79 259 166 51
'TARBP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S764.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TARBP2 MUTATED 3 0 1 2
TARBP2 WILD-TYPE 269 177 232 274
'TARBP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0654 (Fisher's exact test), Q value = 0.61

Table S765.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TARBP2 MUTATED 0 3 1 0 1 1
TARBP2 WILD-TYPE 275 133 205 134 86 119
'TARBP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S766.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TARBP2 MUTATED 0 1 0 1 1
TARBP2 WILD-TYPE 178 119 66 91 111
'TARBP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.768 (Fisher's exact test), Q value = 1

Table S767.  Gene #68: 'TARBP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TARBP2 MUTATED 1 1 1
TARBP2 WILD-TYPE 278 180 107
'RIBC1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S768.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RIBC1 MUTATED 0 1 1 0 2 0 0 0
RIBC1 WILD-TYPE 21 37 113 97 106 73 19 39
'RIBC1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 0.98

Table S769.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RIBC1 MUTATED 1 3 0 0 0
RIBC1 WILD-TYPE 95 149 116 89 56
'RIBC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S770.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RIBC1 MUTATED 2 2 0 0 0
RIBC1 WILD-TYPE 245 361 86 231 36
'RIBC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S771.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
RIBC1 MUTATED 1 0 1 0 0 1
RIBC1 WILD-TYPE 127 96 155 107 109 51
'RIBC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.53 (Fisher's exact test), Q value = 1

Table S772.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RIBC1 MUTATED 3 0 1
RIBC1 WILD-TYPE 502 279 189
'RIBC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S773.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RIBC1 MUTATED 1 0 0 3 0 0
RIBC1 WILD-TYPE 262 151 79 258 168 52
'RIBC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S774.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RIBC1 MUTATED 1 1 2 0
RIBC1 WILD-TYPE 271 176 231 276
'RIBC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.329 (Fisher's exact test), Q value = 0.94

Table S775.  Gene #69: 'RIBC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RIBC1 MUTATED 1 1 0 2 0 0
RIBC1 WILD-TYPE 274 135 206 132 87 120
'PSIP1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S776.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PSIP1 MUTATED 0 0 0 1 1 1 0 1
PSIP1 WILD-TYPE 21 38 114 96 107 72 19 38
'PSIP1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S777.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PSIP1 MUTATED 0 1 1 1 1
PSIP1 WILD-TYPE 96 151 115 88 55
'PSIP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S778.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PSIP1 MUTATED 2 3 2 1 0
PSIP1 WILD-TYPE 245 360 84 230 36
'PSIP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S779.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PSIP1 MUTATED 2 0 2 1 0 0
PSIP1 WILD-TYPE 126 96 154 106 109 52
'PSIP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.689 (Fisher's exact test), Q value = 1

Table S780.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PSIP1 MUTATED 1 1 2
PSIP1 WILD-TYPE 144 130 116
'PSIP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S781.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PSIP1 MUTATED 1 0 1 1 1 0
PSIP1 WILD-TYPE 58 48 89 52 112 31
'PSIP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 0.97

Table S782.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PSIP1 MUTATED 6 2 0
PSIP1 WILD-TYPE 499 277 190
'PSIP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S783.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PSIP1 MUTATED 3 2 0 2 1 0
PSIP1 WILD-TYPE 260 149 79 259 167 52
'PSIP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.86

Table S784.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PSIP1 MUTATED 0 1 2 4
PSIP1 WILD-TYPE 272 176 231 272
'PSIP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S785.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PSIP1 MUTATED 2 1 1 3 0 0
PSIP1 WILD-TYPE 273 135 205 131 87 120
'PSIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S786.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
PSIP1 MUTATED 2 0 0 1 1
PSIP1 WILD-TYPE 176 120 66 91 111
'PSIP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.13 (Fisher's exact test), Q value = 0.75

Table S787.  Gene #70: 'PSIP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
PSIP1 MUTATED 2 0 2
PSIP1 WILD-TYPE 277 181 106
'CEP57 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.373 (Fisher's exact test), Q value = 0.98

Table S788.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CEP57 MUTATED 0 0 0 1 0 2 0 0
CEP57 WILD-TYPE 21 38 114 96 108 71 19 39
'CEP57 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.279 (Fisher's exact test), Q value = 0.93

Table S789.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CEP57 MUTATED 0 0 2 1 0
CEP57 WILD-TYPE 96 152 114 88 56
'CEP57 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.301 (Fisher's exact test), Q value = 0.93

Table S790.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CEP57 MUTATED 0 2 1 3 0
CEP57 WILD-TYPE 247 361 85 228 36
'CEP57 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.188 (Fisher's exact test), Q value = 0.85

Table S791.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CEP57 MUTATED 0 1 1 3 0 0
CEP57 WILD-TYPE 128 95 155 104 109 52
'CEP57 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S792.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CEP57 MUTATED 4 2 0
CEP57 WILD-TYPE 501 277 190
'CEP57 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S793.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CEP57 MUTATED 1 2 0 2 1 0
CEP57 WILD-TYPE 262 149 79 259 167 52
'CEP57 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0703 (Fisher's exact test), Q value = 0.62

Table S794.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CEP57 MUTATED 0 1 4 1
CEP57 WILD-TYPE 272 176 229 275
'CEP57 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.984 (Fisher's exact test), Q value = 1

Table S795.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CEP57 MUTATED 2 1 2 1 0 0
CEP57 WILD-TYPE 273 135 204 133 87 120
'CEP57 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0808 (Fisher's exact test), Q value = 0.67

Table S796.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CEP57 MUTATED 0 0 1 0 2
CEP57 WILD-TYPE 178 120 65 92 110
'CEP57 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0397 (Fisher's exact test), Q value = 0.5

Table S797.  Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CEP57 MUTATED 0 3 0
CEP57 WILD-TYPE 279 178 108

Figure S121.  Get High-res Image Gene #71: 'CEP57 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ANKRD20A4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S798.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ANKRD20A4 MUTATED 0 0 0 0 1 1 1 0
ANKRD20A4 WILD-TYPE 21 38 114 97 107 72 18 39
'ANKRD20A4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0963 (Fisher's exact test), Q value = 0.71

Table S799.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ANKRD20A4 MUTATED 0 0 2 0 1
ANKRD20A4 WILD-TYPE 96 152 114 89 55
'ANKRD20A4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S800.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ANKRD20A4 MUTATED 1 3 0 3 0
ANKRD20A4 WILD-TYPE 246 360 86 228 36
'ANKRD20A4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S801.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ANKRD20A4 MUTATED 2 0 1 1 0 1
ANKRD20A4 WILD-TYPE 126 96 155 106 109 51
'ANKRD20A4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S802.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ANKRD20A4 MUTATED 2 1 0
ANKRD20A4 WILD-TYPE 143 130 118
'ANKRD20A4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S803.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ANKRD20A4 MUTATED 1 0 1 0 1 0
ANKRD20A4 WILD-TYPE 58 48 89 53 112 31
'ANKRD20A4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 0.88

Table S804.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ANKRD20A4 MUTATED 2 2 3
ANKRD20A4 WILD-TYPE 503 277 187
'ANKRD20A4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.332 (Fisher's exact test), Q value = 0.94

Table S805.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ANKRD20A4 MUTATED 2 0 1 3 0 1
ANKRD20A4 WILD-TYPE 261 151 78 258 168 51
'ANKRD20A4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.882 (Fisher's exact test), Q value = 1

Table S806.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ANKRD20A4 MUTATED 2 2 1 2
ANKRD20A4 WILD-TYPE 270 175 232 274
'ANKRD20A4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.967 (Fisher's exact test), Q value = 1

Table S807.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ANKRD20A4 MUTATED 3 1 2 1 0 0
ANKRD20A4 WILD-TYPE 272 135 204 133 87 120
'ANKRD20A4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S808.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ANKRD20A4 MUTATED 1 0 1 1 2
ANKRD20A4 WILD-TYPE 177 120 65 91 110
'ANKRD20A4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.036 (Fisher's exact test), Q value = 0.47

Table S809.  Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ANKRD20A4 MUTATED 0 3 2
ANKRD20A4 WILD-TYPE 279 178 106

Figure S122.  Get High-res Image Gene #72: 'ANKRD20A4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'HIST1H3B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S810.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
HIST1H3B MUTATED 0 0 1 1 0 2 0 1
HIST1H3B WILD-TYPE 21 38 113 96 108 71 19 38
'HIST1H3B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S811.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
HIST1H3B MUTATED 1 1 2 1 0
HIST1H3B WILD-TYPE 95 151 114 88 56
'HIST1H3B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S812.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
HIST1H3B MUTATED 3 3 1 3 1
HIST1H3B WILD-TYPE 244 360 85 228 35
'HIST1H3B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S813.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
HIST1H3B MUTATED 3 2 1 1 2 0
HIST1H3B WILD-TYPE 125 94 155 106 107 52
'HIST1H3B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S814.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
HIST1H3B MUTATED 3 1 1
HIST1H3B WILD-TYPE 142 130 117
'HIST1H3B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S815.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
HIST1H3B MUTATED 0 0 1 1 2 1
HIST1H3B WILD-TYPE 59 48 89 52 111 30
'HIST1H3B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S816.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
HIST1H3B MUTATED 6 3 2
HIST1H3B WILD-TYPE 499 276 188
'HIST1H3B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.169 (Fisher's exact test), Q value = 0.8

Table S817.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
HIST1H3B MUTATED 1 5 1 2 2 0
HIST1H3B WILD-TYPE 262 146 78 259 166 52
'HIST1H3B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S818.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
HIST1H3B MUTATED 3 1 2 5
HIST1H3B WILD-TYPE 269 176 231 271
'HIST1H3B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.178 (Fisher's exact test), Q value = 0.83

Table S819.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
HIST1H3B MUTATED 7 0 1 1 0 2
HIST1H3B WILD-TYPE 268 136 205 133 87 118
'HIST1H3B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S820.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
HIST1H3B MUTATED 3 1 1 0 1
HIST1H3B WILD-TYPE 175 119 65 92 111
'HIST1H3B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.663 (Fisher's exact test), Q value = 1

Table S821.  Gene #73: 'HIST1H3B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
HIST1H3B MUTATED 4 2 0
HIST1H3B WILD-TYPE 275 179 108
'MED23 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0973 (Fisher's exact test), Q value = 0.71

Table S822.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MED23 MUTATED 0 1 1 0 1 1 0 3
MED23 WILD-TYPE 21 37 113 97 107 72 19 36
'MED23 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.282 (Fisher's exact test), Q value = 0.93

Table S823.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MED23 MUTATED 1 5 1 0 0
MED23 WILD-TYPE 95 147 115 89 56
'MED23 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 0.96

Table S824.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MED23 MUTATED 3 9 1 1 0
MED23 WILD-TYPE 244 354 85 230 36
'MED23 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S825.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MED23 MUTATED 2 2 3 1 0 2
MED23 WILD-TYPE 126 94 153 106 109 50
'MED23 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.78

Table S826.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MED23 MUTATED 0 3 1
MED23 WILD-TYPE 145 128 117
'MED23 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.221 (Fisher's exact test), Q value = 0.88

Table S827.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MED23 MUTATED 0 2 0 0 2 0
MED23 WILD-TYPE 59 46 90 53 111 31
'MED23 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0488 (Fisher's exact test), Q value = 0.56

Table S828.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MED23 MUTATED 7 1 6
MED23 WILD-TYPE 498 278 184

Figure S123.  Get High-res Image Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'MED23 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0743 (Fisher's exact test), Q value = 0.64

Table S829.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MED23 MUTATED 3 1 1 9 0 0
MED23 WILD-TYPE 260 150 78 252 168 52
'MED23 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.356 (Fisher's exact test), Q value = 0.96

Table S830.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MED23 MUTATED 2 5 3 4
MED23 WILD-TYPE 270 172 230 272
'MED23 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.389 (Fisher's exact test), Q value = 0.98

Table S831.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MED23 MUTATED 3 1 5 3 2 0
MED23 WILD-TYPE 272 135 201 131 85 120
'MED23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.93

Table S832.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MED23 MUTATED 2 0 1 3 1
MED23 WILD-TYPE 176 120 65 89 111
'MED23 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.416 (Fisher's exact test), Q value = 0.98

Table S833.  Gene #74: 'MED23 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MED23 MUTATED 2 3 2
MED23 WILD-TYPE 277 178 106
'MUC6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0208 (Fisher's exact test), Q value = 0.34

Table S834.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MUC6 MUTATED 2 2 0 3 1 0 0 1
MUC6 WILD-TYPE 19 36 114 94 107 73 19 38

Figure S124.  Get High-res Image Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'MUC6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S835.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MUC6 MUTATED 0 3 3 2 1
MUC6 WILD-TYPE 96 149 113 87 55
'MUC6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S836.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MUC6 MUTATED 4 4 0 6 0
MUC6 WILD-TYPE 243 359 86 225 36
'MUC6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S837.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MUC6 MUTATED 2 1 1 2 3 1
MUC6 WILD-TYPE 126 95 155 105 106 51
'MUC6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.365 (Fisher's exact test), Q value = 0.97

Table S838.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MUC6 MUTATED 4 1 4
MUC6 WILD-TYPE 141 130 114
'MUC6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.941 (Fisher's exact test), Q value = 1

Table S839.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MUC6 MUTATED 1 1 2 2 2 1
MUC6 WILD-TYPE 58 47 88 51 111 30
'MUC6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0618 (Fisher's exact test), Q value = 0.6

Table S840.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MUC6 MUTATED 4 8 2
MUC6 WILD-TYPE 501 271 188
'MUC6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.204 (Fisher's exact test), Q value = 0.86

Table S841.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MUC6 MUTATED 1 3 0 4 5 1
MUC6 WILD-TYPE 262 148 79 257 163 51
'MUC6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.621 (Fisher's exact test), Q value = 1

Table S842.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MUC6 MUTATED 6 1 3 4
MUC6 WILD-TYPE 266 176 230 272
'MUC6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.75

Table S843.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MUC6 MUTATED 6 1 0 2 1 4
MUC6 WILD-TYPE 269 135 206 132 86 116
'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 0.93

Table S844.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MUC6 MUTATED 3 3 0 0 0
MUC6 WILD-TYPE 175 117 66 92 112
'MUC6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0503 (Fisher's exact test), Q value = 0.56

Table S845.  Gene #75: 'MUC6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MUC6 MUTATED 6 0 0
MUC6 WILD-TYPE 273 181 108
'ANGPT4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.203 (Fisher's exact test), Q value = 0.86

Table S846.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ANGPT4 MUTATED 0 1 1 1 0 0 1 0
ANGPT4 WILD-TYPE 21 37 113 96 108 73 18 39
'ANGPT4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S847.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ANGPT4 MUTATED 1 1 1 1 0
ANGPT4 WILD-TYPE 95 151 115 88 56
'ANGPT4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 0.98

Table S848.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ANGPT4 MUTATED 4 2 2 2 0
ANGPT4 WILD-TYPE 243 361 84 229 36
'ANGPT4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.257 (Fisher's exact test), Q value = 0.92

Table S849.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ANGPT4 MUTATED 2 1 0 2 0 1
ANGPT4 WILD-TYPE 126 95 156 105 109 51
'ANGPT4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S850.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ANGPT4 MUTATED 1 2 0
ANGPT4 WILD-TYPE 144 129 118
'ANGPT4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.941 (Fisher's exact test), Q value = 1

Table S851.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ANGPT4 MUTATED 0 0 1 0 2 0
ANGPT4 WILD-TYPE 59 48 89 53 111 31
'ANGPT4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.045 (Fisher's exact test), Q value = 0.53

Table S852.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ANGPT4 MUTATED 2 6 2
ANGPT4 WILD-TYPE 503 273 188

Figure S125.  Get High-res Image Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'ANGPT4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0451 (Fisher's exact test), Q value = 0.53

Table S853.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ANGPT4 MUTATED 1 4 1 1 1 2
ANGPT4 WILD-TYPE 262 147 78 260 167 50

Figure S126.  Get High-res Image Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'ANGPT4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 0.79

Table S854.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ANGPT4 MUTATED 6 2 1 1
ANGPT4 WILD-TYPE 266 175 232 275
'ANGPT4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S855.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ANGPT4 MUTATED 4 3 2 1 0 0
ANGPT4 WILD-TYPE 271 133 204 133 87 120
'ANGPT4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S856.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ANGPT4 MUTATED 1 1 1 1 1
ANGPT4 WILD-TYPE 177 119 65 91 111
'ANGPT4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.416 (Fisher's exact test), Q value = 0.98

Table S857.  Gene #76: 'ANGPT4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ANGPT4 MUTATED 2 3 0
ANGPT4 WILD-TYPE 277 178 108
'PCNXL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.953 (Fisher's exact test), Q value = 1

Table S858.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PCNXL2 MUTATED 0 1 5 2 3 2 0 0
PCNXL2 WILD-TYPE 21 37 109 95 105 71 19 39
'PCNXL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.938 (Fisher's exact test), Q value = 1

Table S859.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PCNXL2 MUTATED 3 3 3 2 2
PCNXL2 WILD-TYPE 93 149 113 87 54
'PCNXL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S860.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PCNXL2 MUTATED 5 6 2 7 1
PCNXL2 WILD-TYPE 242 357 84 224 35
'PCNXL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S861.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PCNXL2 MUTATED 4 1 4 1 3 1
PCNXL2 WILD-TYPE 124 95 152 106 106 51
'PCNXL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 1

Table S862.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PCNXL2 MUTATED 4 4 1
PCNXL2 WILD-TYPE 141 127 117
'PCNXL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S863.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PCNXL2 MUTATED 1 0 1 1 5 1
PCNXL2 WILD-TYPE 58 48 89 52 108 30
'PCNXL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 0.98

Table S864.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PCNXL2 MUTATED 14 5 2
PCNXL2 WILD-TYPE 491 274 188
'PCNXL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S865.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PCNXL2 MUTATED 8 4 1 3 4 1
PCNXL2 WILD-TYPE 255 147 78 258 164 51
'PCNXL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S866.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PCNXL2 MUTATED 7 2 5 7
PCNXL2 WILD-TYPE 265 175 228 269
'PCNXL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S867.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PCNXL2 MUTATED 9 2 2 4 2 2
PCNXL2 WILD-TYPE 266 134 204 130 85 118
'PCNXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.972 (Fisher's exact test), Q value = 1

Table S868.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
PCNXL2 MUTATED 4 2 1 1 1
PCNXL2 WILD-TYPE 174 118 65 91 111
'PCNXL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S869.  Gene #77: 'PCNXL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
PCNXL2 MUTATED 5 2 2
PCNXL2 WILD-TYPE 274 179 106
'SLC35B2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S870.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SLC35B2 MUTATED 0 0 1 1 1 1 0 0
SLC35B2 WILD-TYPE 21 38 113 96 107 72 19 39
'SLC35B2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.248 (Fisher's exact test), Q value = 0.91

Table S871.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SLC35B2 MUTATED 1 0 2 0 1
SLC35B2 WILD-TYPE 95 152 114 89 55
'SLC35B2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S872.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SLC35B2 MUTATED 1 3 1 2 0
SLC35B2 WILD-TYPE 246 360 85 229 36
'SLC35B2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S873.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
SLC35B2 MUTATED 2 2 0
SLC35B2 WILD-TYPE 143 129 118
'SLC35B2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S874.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
SLC35B2 MUTATED 1 0 2 0 1 0
SLC35B2 WILD-TYPE 58 48 88 53 112 31
'SLC35B2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S875.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SLC35B2 MUTATED 3 3 1
SLC35B2 WILD-TYPE 502 276 189
'SLC35B2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S876.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SLC35B2 MUTATED 2 1 0 2 1 1
SLC35B2 WILD-TYPE 261 150 79 259 167 51
'SLC35B2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.622 (Fisher's exact test), Q value = 1

Table S877.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SLC35B2 MUTATED 3 0 2 2
SLC35B2 WILD-TYPE 269 177 231 274
'SLC35B2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S878.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SLC35B2 MUTATED 3 1 1 1 1 0
SLC35B2 WILD-TYPE 272 135 205 133 86 120
'SLC35B2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.929 (Fisher's exact test), Q value = 1

Table S879.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SLC35B2 MUTATED 2 1 1 0 1
SLC35B2 WILD-TYPE 176 119 65 92 111
'SLC35B2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S880.  Gene #78: 'SLC35B2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SLC35B2 MUTATED 2 2 1
SLC35B2 WILD-TYPE 277 179 107
'MKL1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S881.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MKL1 MUTATED 0 0 2 0 1 1 0 0
MKL1 WILD-TYPE 21 38 112 97 107 72 19 39
'MKL1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S882.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MKL1 MUTATED 2 1 1 0 0
MKL1 WILD-TYPE 94 151 115 89 56
'MKL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 0.98

Table S883.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MKL1 MUTATED 3 2 0 0 0
MKL1 WILD-TYPE 244 361 86 231 36
'MKL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S884.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MKL1 MUTATED 2 1 0
MKL1 WILD-TYPE 143 130 118
'MKL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.346 (Fisher's exact test), Q value = 0.96

Table S885.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MKL1 MUTATED 0 0 0 0 2 1
MKL1 WILD-TYPE 59 48 90 53 111 30
'MKL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S886.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MKL1 MUTATED 3 2 0
MKL1 WILD-TYPE 502 277 190
'MKL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.75

Table S887.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MKL1 MUTATED 2 2 0 0 0 1
MKL1 WILD-TYPE 261 149 79 261 168 51
'MKL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S888.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MKL1 MUTATED 2 0 1 2
MKL1 WILD-TYPE 270 177 232 274
'MKL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 0.98

Table S889.  Gene #79: 'MKL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MKL1 MUTATED 3 1 0 0 1 0
MKL1 WILD-TYPE 272 135 206 134 86 120
'NBPF9 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S890.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
NBPF9 MUTATED 1 0 1 1 2 0 0 0
NBPF9 WILD-TYPE 20 38 113 96 106 73 19 39
'NBPF9 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S891.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
NBPF9 MUTATED 0 1 2 1 1
NBPF9 WILD-TYPE 96 151 114 88 55
'NBPF9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.805 (Fisher's exact test), Q value = 1

Table S892.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
NBPF9 MUTATED 1 2 1 1 0
NBPF9 WILD-TYPE 246 361 85 230 36
'NBPF9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S893.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
NBPF9 MUTATED 2 1 2
NBPF9 WILD-TYPE 143 130 116
'NBPF9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S894.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
NBPF9 MUTATED 1 0 1 2 1 0
NBPF9 WILD-TYPE 58 48 89 51 112 31
'NBPF9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.6 (Fisher's exact test), Q value = 1

Table S895.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
NBPF9 MUTATED 4 1 0
NBPF9 WILD-TYPE 501 278 190
'NBPF9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.155 (Fisher's exact test), Q value = 0.78

Table S896.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
NBPF9 MUTATED 1 3 0 0 1 0
NBPF9 WILD-TYPE 262 148 79 261 167 52
'NBPF9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 0.77

Table S897.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
NBPF9 MUTATED 2 0 3 0
NBPF9 WILD-TYPE 270 177 230 276
'NBPF9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S898.  Gene #80: 'NBPF9 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
NBPF9 MUTATED 2 2 0 0 1 0
NBPF9 WILD-TYPE 273 134 206 134 86 120
'PRICKLE3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.92

Table S899.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PRICKLE3 MUTATED 1 0 0 3 1 2 0 0
PRICKLE3 WILD-TYPE 20 38 114 94 107 71 19 39
'PRICKLE3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0267 (Fisher's exact test), Q value = 0.39

Table S900.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PRICKLE3 MUTATED 0 0 2 3 2
PRICKLE3 WILD-TYPE 96 152 114 86 54

Figure S127.  Get High-res Image Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'PRICKLE3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S901.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PRICKLE3 MUTATED 2 3 2 3 0
PRICKLE3 WILD-TYPE 245 360 84 228 36
'PRICKLE3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.743 (Fisher's exact test), Q value = 1

Table S902.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PRICKLE3 MUTATED 1 2 1 1 0 0
PRICKLE3 WILD-TYPE 127 94 155 106 109 52
'PRICKLE3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S903.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PRICKLE3 MUTATED 4 1 2
PRICKLE3 WILD-TYPE 141 130 116
'PRICKLE3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S904.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PRICKLE3 MUTATED 0 0 2 2 2 1
PRICKLE3 WILD-TYPE 59 48 88 51 111 30
'PRICKLE3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.85

Table S905.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PRICKLE3 MUTATED 4 6 1
PRICKLE3 WILD-TYPE 501 273 189
'PRICKLE3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.206 (Fisher's exact test), Q value = 0.86

Table S906.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PRICKLE3 MUTATED 2 4 0 1 3 1
PRICKLE3 WILD-TYPE 261 147 79 260 165 51
'PRICKLE3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S907.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PRICKLE3 MUTATED 4 2 1 4
PRICKLE3 WILD-TYPE 268 175 232 272
'PRICKLE3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 0.98

Table S908.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PRICKLE3 MUTATED 2 3 1 1 1 3
PRICKLE3 WILD-TYPE 273 133 205 133 86 117
'PRICKLE3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S909.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
PRICKLE3 MUTATED 2 0 1 0 1
PRICKLE3 WILD-TYPE 176 120 65 92 111
'PRICKLE3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S910.  Gene #81: 'PRICKLE3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
PRICKLE3 MUTATED 2 2 0
PRICKLE3 WILD-TYPE 277 179 108
'CCDC82 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S911.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CCDC82 MUTATED 0 0 3 0 0 1 0 0
CCDC82 WILD-TYPE 21 38 111 97 108 72 19 39
'CCDC82 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.059 (Fisher's exact test), Q value = 0.6

Table S912.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CCDC82 MUTATED 3 0 1 0 0
CCDC82 WILD-TYPE 93 152 115 89 56
'CCDC82 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.302 (Fisher's exact test), Q value = 0.93

Table S913.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CCDC82 MUTATED 0 2 1 3 0
CCDC82 WILD-TYPE 247 361 85 228 36
'CCDC82 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0372 (Fisher's exact test), Q value = 0.48

Table S914.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CCDC82 MUTATED 4 0 0
CCDC82 WILD-TYPE 141 131 118

Figure S128.  Get High-res Image Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'CCDC82 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S915.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CCDC82 MUTATED 0 0 1 0 3 0
CCDC82 WILD-TYPE 59 48 89 53 110 31
'CCDC82 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 0.96

Table S916.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CCDC82 MUTATED 5 1 0
CCDC82 WILD-TYPE 500 278 190
'CCDC82 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00251 (Fisher's exact test), Q value = 0.072

Table S917.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CCDC82 MUTATED 0 5 0 0 1 0
CCDC82 WILD-TYPE 263 146 79 261 167 52

Figure S129.  Get High-res Image Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'CCDC82 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 0.93

Table S918.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CCDC82 MUTATED 4 0 1 1
CCDC82 WILD-TYPE 268 177 232 275
'CCDC82 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S919.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CCDC82 MUTATED 3 0 1 1 0 1
CCDC82 WILD-TYPE 272 136 205 133 87 119
'CCDC82 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S920.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CCDC82 MUTATED 1 1 0 0 1
CCDC82 WILD-TYPE 177 119 66 92 111
'CCDC82 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S921.  Gene #82: 'CCDC82 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CCDC82 MUTATED 2 1 0
CCDC82 WILD-TYPE 277 180 108
'CXCR3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S922.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CXCR3 MUTATED 0 0 1 1 0 0 0 1
CXCR3 WILD-TYPE 21 38 113 96 108 73 19 38
'CXCR3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S923.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CXCR3 MUTATED 1 1 0 1 0
CXCR3 WILD-TYPE 95 151 116 88 56
'CXCR3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.156 (Fisher's exact test), Q value = 0.78

Table S924.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CXCR3 MUTATED 0 4 0 1 1
CXCR3 WILD-TYPE 247 359 86 230 35
'CXCR3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S925.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CXCR3 MUTATED 0 1 2 0 0 0
CXCR3 WILD-TYPE 128 95 154 107 109 52
'CXCR3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S926.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CXCR3 MUTATED 1 1 1
CXCR3 WILD-TYPE 144 130 117
'CXCR3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S927.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CXCR3 MUTATED 0 0 1 1 1 0
CXCR3 WILD-TYPE 59 48 89 52 112 31
'CXCR3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 1

Table S928.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CXCR3 MUTATED 4 2 0
CXCR3 WILD-TYPE 501 277 190
'CXCR3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S929.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CXCR3 MUTATED 1 0 1 2 1 1
CXCR3 WILD-TYPE 262 151 78 259 167 51
'CXCR3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S930.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CXCR3 MUTATED 2 2 1 1
CXCR3 WILD-TYPE 270 175 232 275
'CXCR3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S931.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CXCR3 MUTATED 3 0 1 1 0 1
CXCR3 WILD-TYPE 272 136 205 133 87 119
'CXCR3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S932.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CXCR3 MUTATED 1 0 0 1 2
CXCR3 WILD-TYPE 177 120 66 91 110
'CXCR3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S933.  Gene #83: 'CXCR3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CXCR3 MUTATED 1 2 1
CXCR3 WILD-TYPE 278 179 107
'TPP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0857 (Fisher's exact test), Q value = 0.68

Table S934.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TPP2 MUTATED 1 0 0 0 3 0 0 0
TPP2 WILD-TYPE 20 38 114 97 105 73 19 39
'TPP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.945 (Fisher's exact test), Q value = 1

Table S935.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TPP2 MUTATED 1 2 1 0 0
TPP2 WILD-TYPE 95 150 115 89 56
'TPP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S936.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TPP2 MUTATED 4 2 0 2 0
TPP2 WILD-TYPE 243 361 86 229 36
'TPP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.26 (Fisher's exact test), Q value = 0.92

Table S937.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TPP2 MUTATED 0 0 3 0 2 0
TPP2 WILD-TYPE 128 96 153 107 107 52
'TPP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.362 (Fisher's exact test), Q value = 0.97

Table S938.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TPP2 MUTATED 6 2 0
TPP2 WILD-TYPE 499 277 190
'TPP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.915 (Fisher's exact test), Q value = 1

Table S939.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TPP2 MUTATED 2 2 0 2 2 0
TPP2 WILD-TYPE 261 149 79 259 166 52
'TPP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.531 (Fisher's exact test), Q value = 1

Table S940.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TPP2 MUTATED 3 0 3 2
TPP2 WILD-TYPE 269 177 230 274
'TPP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S941.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TPP2 MUTATED 2 1 1 1 1 2
TPP2 WILD-TYPE 273 135 205 133 86 118
'TPP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S942.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TPP2 MUTATED 2 2 0 0 1
TPP2 WILD-TYPE 176 118 66 92 111
'TPP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.595 (Fisher's exact test), Q value = 1

Table S943.  Gene #84: 'TPP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TPP2 MUTATED 4 1 0
TPP2 WILD-TYPE 275 180 108
'C15ORF39 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S944.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
C15ORF39 MUTATED 0 0 0 2 1 2 0 0
C15ORF39 WILD-TYPE 21 38 114 95 107 71 19 39
'C15ORF39 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S945.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
C15ORF39 MUTATED 0 1 2 2 0
C15ORF39 WILD-TYPE 96 151 114 87 56
'C15ORF39 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00456 (Fisher's exact test), Q value = 0.12

Table S946.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
C15ORF39 MUTATED 1 0 0 6 1
C15ORF39 WILD-TYPE 246 363 86 225 35

Figure S130.  Get High-res Image Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'C15ORF39 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0143 (Fisher's exact test), Q value = 0.26

Table S947.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
C15ORF39 MUTATED 1 0 0 0 4 0
C15ORF39 WILD-TYPE 127 96 156 107 105 52

Figure S131.  Get High-res Image Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'C15ORF39 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 1

Table S948.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
C15ORF39 MUTATED 2 0 1
C15ORF39 WILD-TYPE 143 131 117
'C15ORF39 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.391 (Fisher's exact test), Q value = 0.98

Table S949.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
C15ORF39 MUTATED 0 0 2 1 0 0
C15ORF39 WILD-TYPE 59 48 88 52 113 31
'C15ORF39 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00705 (Fisher's exact test), Q value = 0.17

Table S950.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
C15ORF39 MUTATED 2 7 0
C15ORF39 WILD-TYPE 503 272 190

Figure S132.  Get High-res Image Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'C15ORF39 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00119 (Fisher's exact test), Q value = 0.039

Table S951.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
C15ORF39 MUTATED 0 2 0 0 6 1
C15ORF39 WILD-TYPE 263 149 79 261 162 51

Figure S133.  Get High-res Image Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0231 (Fisher's exact test), Q value = 0.37

Table S952.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
C15ORF39 MUTATED 6 1 1 0
C15ORF39 WILD-TYPE 266 176 232 276

Figure S134.  Get High-res Image Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0291 (Fisher's exact test), Q value = 0.4

Table S953.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
C15ORF39 MUTATED 2 2 0 0 0 4
C15ORF39 WILD-TYPE 273 134 206 134 87 116

Figure S135.  Get High-res Image Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.98

Table S954.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
C15ORF39 MUTATED 1 3 0 0 1
C15ORF39 WILD-TYPE 177 117 66 92 111
'C15ORF39 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.127 (Fisher's exact test), Q value = 0.75

Table S955.  Gene #85: 'C15ORF39 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
C15ORF39 MUTATED 5 0 0
C15ORF39 WILD-TYPE 274 181 108
'CASP8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.463 (Fisher's exact test), Q value = 1

Table S956.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CASP8 MUTATED 0 0 1 0 3 0 0 1
CASP8 WILD-TYPE 21 38 113 97 105 73 19 38
'CASP8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 0.98

Table S957.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CASP8 MUTATED 1 3 0 0 1
CASP8 WILD-TYPE 95 149 116 89 55
'CASP8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.26 (Fisher's exact test), Q value = 0.92

Table S958.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CASP8 MUTATED 1 5 3 3 0
CASP8 WILD-TYPE 246 358 83 228 36
'CASP8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S959.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CASP8 MUTATED 0 0 4 2 2 1
CASP8 WILD-TYPE 128 96 152 105 107 51
'CASP8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.529 (Fisher's exact test), Q value = 1

Table S960.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CASP8 MUTATED 1 3 1
CASP8 WILD-TYPE 144 128 117
'CASP8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S961.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CASP8 MUTATED 2 1 1 0 1 0
CASP8 WILD-TYPE 57 47 89 53 112 31
'CASP8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S962.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CASP8 MUTATED 7 3 2
CASP8 WILD-TYPE 498 276 188
'CASP8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S963.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CASP8 MUTATED 2 2 0 5 3 0
CASP8 WILD-TYPE 261 149 79 256 165 52
'CASP8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S964.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CASP8 MUTATED 4 1 5 2
CASP8 WILD-TYPE 268 176 228 274
'CASP8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S965.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CASP8 MUTATED 2 2 2 3 0 3
CASP8 WILD-TYPE 273 134 204 131 87 117
'CASP8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 0.82

Table S966.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CASP8 MUTATED 1 3 2 1 0
CASP8 WILD-TYPE 177 117 64 91 112
'CASP8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S967.  Gene #86: 'CASP8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CASP8 MUTATED 4 2 1
CASP8 WILD-TYPE 275 179 107
'TNRC6B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.519 (Fisher's exact test), Q value = 1

Table S968.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TNRC6B MUTATED 0 1 1 4 3 0 0 0
TNRC6B WILD-TYPE 21 37 113 93 105 73 19 39
'TNRC6B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.157 (Fisher's exact test), Q value = 0.78

Table S969.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TNRC6B MUTATED 1 3 0 4 1
TNRC6B WILD-TYPE 95 149 116 85 55
'TNRC6B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.576 (Fisher's exact test), Q value = 1

Table S970.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TNRC6B MUTATED 2 8 1 6 0
TNRC6B WILD-TYPE 245 355 85 225 36
'TNRC6B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.77

Table S971.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TNRC6B MUTATED 0 5 5 2 2 1
TNRC6B WILD-TYPE 128 91 151 105 107 51
'TNRC6B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.508 (Fisher's exact test), Q value = 1

Table S972.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TNRC6B MUTATED 4 1 2
TNRC6B WILD-TYPE 141 130 116
'TNRC6B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S973.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TNRC6B MUTATED 1 0 4 1 1 0
TNRC6B WILD-TYPE 58 48 86 52 112 31
'TNRC6B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S974.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TNRC6B MUTATED 10 6 2
TNRC6B WILD-TYPE 495 273 188
'TNRC6B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.327 (Fisher's exact test), Q value = 0.94

Table S975.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TNRC6B MUTATED 2 4 0 6 5 1
TNRC6B WILD-TYPE 261 147 79 255 163 51
'TNRC6B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.951 (Fisher's exact test), Q value = 1

Table S976.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TNRC6B MUTATED 4 3 5 6
TNRC6B WILD-TYPE 268 174 228 270
'TNRC6B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.202 (Fisher's exact test), Q value = 0.86

Table S977.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TNRC6B MUTATED 3 2 4 6 0 3
TNRC6B WILD-TYPE 272 134 202 128 87 117
'TNRC6B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.654 (Fisher's exact test), Q value = 1

Table S978.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TNRC6B MUTATED 2 3 1 0 2
TNRC6B WILD-TYPE 176 117 65 92 110
'TNRC6B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.369 (Fisher's exact test), Q value = 0.98

Table S979.  Gene #87: 'TNRC6B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TNRC6B MUTATED 4 4 0
TNRC6B WILD-TYPE 275 177 108
'OXCT2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S980.  Gene #88: 'OXCT2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
OXCT2 MUTATED 0 1 0 0 1 1 0 0
OXCT2 WILD-TYPE 21 37 114 97 107 72 19 39
'OXCT2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S981.  Gene #88: 'OXCT2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
OXCT2 MUTATED 0 1 1 0 1
OXCT2 WILD-TYPE 96 151 115 89 55
'OXCT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.896 (Fisher's exact test), Q value = 1

Table S982.  Gene #88: 'OXCT2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
OXCT2 MUTATED 2 1 0 1 0
OXCT2 WILD-TYPE 245 362 86 230 36
'OXCT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S983.  Gene #88: 'OXCT2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
OXCT2 MUTATED 2 1 1
OXCT2 WILD-TYPE 503 278 189
'OXCT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S984.  Gene #88: 'OXCT2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
OXCT2 MUTATED 1 1 0 1 0 1
OXCT2 WILD-TYPE 262 150 79 260 168 51
'OXCT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S985.  Gene #88: 'OXCT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
OXCT2 MUTATED 1 1 1 1
OXCT2 WILD-TYPE 271 176 232 275
'OXCT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S986.  Gene #88: 'OXCT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
OXCT2 MUTATED 1 1 0 1 1 0
OXCT2 WILD-TYPE 274 135 206 133 86 120
'IRS4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.144 (Fisher's exact test), Q value = 0.77

Table S987.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
IRS4 MUTATED 1 2 1 1 0 1 0 1
IRS4 WILD-TYPE 20 36 113 96 108 72 19 38
'IRS4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S988.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
IRS4 MUTATED 1 4 1 1 0
IRS4 WILD-TYPE 95 148 115 88 56
'IRS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 0.88

Table S989.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
IRS4 MUTATED 3 2 0 6 0
IRS4 WILD-TYPE 244 361 86 225 36
'IRS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S990.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
IRS4 MUTATED 2 1 1 1 3 1
IRS4 WILD-TYPE 126 95 155 106 106 51
'IRS4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 0.98

Table S991.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
IRS4 MUTATED 3 2 0
IRS4 WILD-TYPE 142 129 118
'IRS4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.845 (Fisher's exact test), Q value = 1

Table S992.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
IRS4 MUTATED 1 0 1 0 3 0
IRS4 WILD-TYPE 58 48 89 53 110 31
'IRS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 0.87

Table S993.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
IRS4 MUTATED 3 5 3
IRS4 WILD-TYPE 502 274 187
'IRS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S994.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
IRS4 MUTATED 2 0 1 4 3 1
IRS4 WILD-TYPE 261 151 78 257 165 51
'IRS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S995.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
IRS4 MUTATED 3 2 2 3
IRS4 WILD-TYPE 269 175 231 273
'IRS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.173 (Fisher's exact test), Q value = 0.82

Table S996.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
IRS4 MUTATED 3 3 0 3 0 1
IRS4 WILD-TYPE 272 133 206 131 87 119
'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.948 (Fisher's exact test), Q value = 1

Table S997.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
IRS4 MUTATED 2 1 0 0 1
IRS4 WILD-TYPE 176 119 66 92 111
'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S998.  Gene #89: 'IRS4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
IRS4 MUTATED 3 1 0
IRS4 WILD-TYPE 276 180 108
'MLL4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.397 (Fisher's exact test), Q value = 0.98

Table S999.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MLL4 MUTATED 1 1 4 2 0 1 0 1
MLL4 WILD-TYPE 20 37 110 95 108 72 19 38
'MLL4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S1000.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MLL4 MUTATED 4 2 2 2 0
MLL4 WILD-TYPE 92 150 114 87 56
'MLL4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S1001.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MLL4 MUTATED 3 4 2 4 0
MLL4 WILD-TYPE 244 359 84 227 36
'MLL4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.88

Table S1002.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MLL4 MUTATED 3 0 1 0 0 0
MLL4 WILD-TYPE 125 96 155 107 109 52
'MLL4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.75

Table S1003.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MLL4 MUTATED 6 1 1
MLL4 WILD-TYPE 139 130 117
'MLL4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S1004.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MLL4 MUTATED 0 1 3 0 4 0
MLL4 WILD-TYPE 59 47 87 53 109 31
'MLL4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S1005.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MLL4 MUTATED 5 5 3
MLL4 WILD-TYPE 500 274 187
'MLL4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.93

Table S1006.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MLL4 MUTATED 2 5 0 3 2 1
MLL4 WILD-TYPE 261 146 79 258 166 51
'MLL4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 0.94

Table S1007.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MLL4 MUTATED 7 1 2 3
MLL4 WILD-TYPE 265 176 231 273
'MLL4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0911 (Fisher's exact test), Q value = 0.69

Table S1008.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MLL4 MUTATED 7 4 1 0 0 1
MLL4 WILD-TYPE 268 132 205 134 87 119
'MLL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 0.96

Table S1009.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MLL4 MUTATED 3 0 0 0 0
MLL4 WILD-TYPE 175 120 66 92 112
'MLL4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S1010.  Gene #90: 'MLL4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MLL4 MUTATED 3 0 0
MLL4 WILD-TYPE 276 181 108
'RHOA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S1011.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RHOA MUTATED 0 0 1 1 0 1 0 0
RHOA WILD-TYPE 21 38 113 96 108 72 19 39
'RHOA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S1012.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RHOA MUTATED 1 0 1 1 0
RHOA WILD-TYPE 95 152 115 88 56
'RHOA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1013.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RHOA MUTATED 1 3 1 1 0
RHOA WILD-TYPE 246 360 85 230 36
'RHOA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.968 (Fisher's exact test), Q value = 1

Table S1014.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
RHOA MUTATED 1 1 1 0 1 0
RHOA WILD-TYPE 127 95 155 107 108 52
'RHOA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 0.75

Table S1015.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
RHOA MUTATED 3 0 0
RHOA WILD-TYPE 142 131 118
'RHOA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S1016.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
RHOA MUTATED 0 0 1 0 1 1
RHOA WILD-TYPE 59 48 89 53 112 30
'RHOA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 0.98

Table S1017.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RHOA MUTATED 3 3 0
RHOA WILD-TYPE 502 276 190
'RHOA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 0.92

Table S1018.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RHOA MUTATED 0 2 0 2 1 1
RHOA WILD-TYPE 263 149 79 259 167 51
'RHOA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1019.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RHOA MUTATED 2 1 1 2
RHOA WILD-TYPE 270 176 232 274
'RHOA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1020.  Gene #91: 'RHOA MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RHOA MUTATED 3 0 2 0 0 1
RHOA WILD-TYPE 272 136 204 134 87 119
'ATHL1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.87 (Fisher's exact test), Q value = 1

Table S1021.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ATHL1 MUTATED 0 0 3 1 2 0 0 0
ATHL1 WILD-TYPE 21 38 111 96 106 73 19 39
'ATHL1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.319 (Fisher's exact test), Q value = 0.94

Table S1022.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ATHL1 MUTATED 3 2 0 1 0
ATHL1 WILD-TYPE 93 150 116 88 56
'ATHL1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0851 (Fisher's exact test), Q value = 0.68

Table S1023.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ATHL1 MUTATED 3 1 0 5 1
ATHL1 WILD-TYPE 244 362 86 226 35
'ATHL1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.77

Table S1024.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ATHL1 MUTATED 3 2 0 0 1 1
ATHL1 WILD-TYPE 125 94 156 107 108 51
'ATHL1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1025.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ATHL1 MUTATED 2 2 1
ATHL1 WILD-TYPE 143 129 117
'ATHL1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S1026.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ATHL1 MUTATED 0 0 1 1 3 0
ATHL1 WILD-TYPE 59 48 89 52 110 31
'ATHL1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.333 (Fisher's exact test), Q value = 0.95

Table S1027.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ATHL1 MUTATED 7 3 0
ATHL1 WILD-TYPE 498 276 190
'ATHL1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.77

Table S1028.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ATHL1 MUTATED 1 5 0 2 2 0
ATHL1 WILD-TYPE 262 146 79 259 166 52
'ATHL1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.186 (Fisher's exact test), Q value = 0.84

Table S1029.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ATHL1 MUTATED 5 0 1 4
ATHL1 WILD-TYPE 267 177 232 272
'ATHL1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.053 (Fisher's exact test), Q value = 0.58

Table S1030.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ATHL1 MUTATED 7 1 0 0 0 2
ATHL1 WILD-TYPE 268 135 206 134 87 118
'ATHL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.343 (Fisher's exact test), Q value = 0.96

Table S1031.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ATHL1 MUTATED 5 1 0 0 1
ATHL1 WILD-TYPE 173 119 66 92 111
'ATHL1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S1032.  Gene #92: 'ATHL1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ATHL1 MUTATED 5 1 1
ATHL1 WILD-TYPE 274 180 107
'LILRA6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S1033.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
LILRA6 MUTATED 0 0 0 1 1 2 0 0
LILRA6 WILD-TYPE 21 38 114 96 107 71 19 39
'LILRA6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.219 (Fisher's exact test), Q value = 0.88

Table S1034.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
LILRA6 MUTATED 0 0 2 1 1
LILRA6 WILD-TYPE 96 152 114 88 55
'LILRA6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S1035.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
LILRA6 MUTATED 2 2 1 1 0
LILRA6 WILD-TYPE 245 361 85 230 36
'LILRA6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.86

Table S1036.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
LILRA6 MUTATED 1 3 0
LILRA6 WILD-TYPE 144 128 118
'LILRA6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1037.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
LILRA6 MUTATED 1 0 1 0 2 0
LILRA6 WILD-TYPE 58 48 89 53 111 31
'LILRA6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S1038.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
LILRA6 MUTATED 4 1 1
LILRA6 WILD-TYPE 501 278 189
'LILRA6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S1039.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
LILRA6 MUTATED 1 2 1 1 1 0
LILRA6 WILD-TYPE 262 149 78 260 167 52
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.371 (Fisher's exact test), Q value = 0.98

Table S1040.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
LILRA6 MUTATED 0 1 1 3
LILRA6 WILD-TYPE 272 176 232 273
'LILRA6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.96 (Fisher's exact test), Q value = 1

Table S1041.  Gene #93: 'LILRA6 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
LILRA6 MUTATED 2 0 1 1 0 1
LILRA6 WILD-TYPE 273 136 205 133 87 119
'SDC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1042.  Gene #94: 'SDC1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SDC1 MUTATED 1 1 0 1 0
SDC1 WILD-TYPE 246 362 86 230 36
'SDC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.93

Table S1043.  Gene #94: 'SDC1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SDC1 MUTATED 1 2 0
SDC1 WILD-TYPE 504 277 190
'SDC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00717 (Fisher's exact test), Q value = 0.17

Table S1044.  Gene #94: 'SDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SDC1 MUTATED 0 0 0 1 0 2
SDC1 WILD-TYPE 263 151 79 260 168 50

Figure S136.  Get High-res Image Gene #94: 'SDC1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SDC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S1045.  Gene #94: 'SDC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SDC1 MUTATED 0 0 1 2
SDC1 WILD-TYPE 272 177 232 274
'SDC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1046.  Gene #94: 'SDC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SDC1 MUTATED 2 0 1 0 0 0
SDC1 WILD-TYPE 273 136 205 134 87 120
'MLH1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S1047.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MLH1 MUTATED 0 0 1 0 2 0 0 0
MLH1 WILD-TYPE 21 38 113 97 106 73 19 39
'MLH1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S1048.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MLH1 MUTATED 1 2 0 0 0
MLH1 WILD-TYPE 95 150 116 89 56
'MLH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S1049.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MLH1 MUTATED 1 3 0 2 0
MLH1 WILD-TYPE 246 360 86 229 36
'MLH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S1050.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MLH1 MUTATED 2 0 1 0 1 0
MLH1 WILD-TYPE 126 96 155 107 108 52
'MLH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.345 (Fisher's exact test), Q value = 0.96

Table S1051.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MLH1 MUTATED 5 1 0
MLH1 WILD-TYPE 500 278 190
'MLH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S1052.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MLH1 MUTATED 2 2 0 1 1 0
MLH1 WILD-TYPE 261 149 79 260 167 52
'MLH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.816 (Fisher's exact test), Q value = 1

Table S1053.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MLH1 MUTATED 2 0 2 2
MLH1 WILD-TYPE 270 177 231 274
'MLH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S1054.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MLH1 MUTATED 4 0 1 0 0 1
MLH1 WILD-TYPE 271 136 205 134 87 119
'MLH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.949 (Fisher's exact test), Q value = 1

Table S1055.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MLH1 MUTATED 2 1 0 0 1
MLH1 WILD-TYPE 176 119 66 92 111
'MLH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S1056.  Gene #95: 'MLH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MLH1 MUTATED 3 1 0
MLH1 WILD-TYPE 276 180 108
'NUP93 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0157 (Fisher's exact test), Q value = 0.28

Table S1057.  Gene #96: 'NUP93 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
NUP93 MUTATED 0 0 0 3 1
NUP93 WILD-TYPE 247 363 86 228 35

Figure S137.  Get High-res Image Gene #96: 'NUP93 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

'NUP93 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S1058.  Gene #96: 'NUP93 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
NUP93 MUTATED 1 0 0 1 2 0
NUP93 WILD-TYPE 127 96 156 106 107 52
'NUP93 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.421 (Fisher's exact test), Q value = 0.98

Table S1059.  Gene #96: 'NUP93 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
NUP93 MUTATED 1 2 1
NUP93 WILD-TYPE 504 277 189
'NUP93 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S1060.  Gene #96: 'NUP93 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
NUP93 MUTATED 0 1 1 1 1 0
NUP93 WILD-TYPE 263 150 78 260 167 52
'NUP93 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S1061.  Gene #96: 'NUP93 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
NUP93 MUTATED 0 0 1 2
NUP93 WILD-TYPE 272 177 232 274
'NUP93 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.502 (Fisher's exact test), Q value = 1

Table S1062.  Gene #96: 'NUP93 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
NUP93 MUTATED 3 0 0 0 0 0
NUP93 WILD-TYPE 272 136 206 134 87 120
'ALDH1L1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S1063.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ALDH1L1 MUTATED 0 1 2 1 0 1 0 1
ALDH1L1 WILD-TYPE 21 37 112 96 108 72 19 38
'ALDH1L1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S1064.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ALDH1L1 MUTATED 2 2 1 1 0
ALDH1L1 WILD-TYPE 94 150 115 88 56
'ALDH1L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.91

Table S1065.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ALDH1L1 MUTATED 4 1 0 4 0
ALDH1L1 WILD-TYPE 243 362 86 227 36
'ALDH1L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.177 (Fisher's exact test), Q value = 0.83

Table S1066.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ALDH1L1 MUTATED 2 0 1 0 2 2
ALDH1L1 WILD-TYPE 126 96 155 107 107 50
'ALDH1L1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.692 (Fisher's exact test), Q value = 1

Table S1067.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ALDH1L1 MUTATED 1 1 2
ALDH1L1 WILD-TYPE 144 130 116
'ALDH1L1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 0.92

Table S1068.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ALDH1L1 MUTATED 0 1 0 2 1 0
ALDH1L1 WILD-TYPE 59 47 90 51 112 31
'ALDH1L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.75

Table S1069.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ALDH1L1 MUTATED 2 5 2
ALDH1L1 WILD-TYPE 503 274 188
'ALDH1L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S1070.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ALDH1L1 MUTATED 1 3 1 1 2 1
ALDH1L1 WILD-TYPE 262 148 78 260 166 51
'ALDH1L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.93

Table S1071.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ALDH1L1 MUTATED 4 2 0 3
ALDH1L1 WILD-TYPE 268 175 233 273
'ALDH1L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.279 (Fisher's exact test), Q value = 0.93

Table S1072.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ALDH1L1 MUTATED 3 2 0 3 0 1
ALDH1L1 WILD-TYPE 272 134 206 131 87 119
'ALDH1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S1073.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ALDH1L1 MUTATED 2 1 0 1 0
ALDH1L1 WILD-TYPE 176 119 66 91 112
'ALDH1L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S1074.  Gene #97: 'ALDH1L1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ALDH1L1 MUTATED 3 1 0
ALDH1L1 WILD-TYPE 276 180 108
'TMEM120B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.257 (Fisher's exact test), Q value = 0.92

Table S1075.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TMEM120B MUTATED 0 0 0 1 1 0 1 0
TMEM120B WILD-TYPE 21 38 114 96 107 73 18 39
'TMEM120B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.247 (Fisher's exact test), Q value = 0.91

Table S1076.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TMEM120B MUTATED 0 0 1 1 1
TMEM120B WILD-TYPE 96 152 115 88 55
'TMEM120B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S1077.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TMEM120B MUTATED 1 2 0 2 0
TMEM120B WILD-TYPE 246 361 86 229 36
'TMEM120B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.977 (Fisher's exact test), Q value = 1

Table S1078.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TMEM120B MUTATED 1 0 2 1 1 0
TMEM120B WILD-TYPE 127 96 154 106 108 52
'TMEM120B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.88

Table S1079.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TMEM120B MUTATED 1 2 2
TMEM120B WILD-TYPE 504 277 188
'TMEM120B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S1080.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TMEM120B MUTATED 1 1 1 1 1 0
TMEM120B WILD-TYPE 262 150 78 260 167 52
'TMEM120B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S1081.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TMEM120B MUTATED 2 1 2 0
TMEM120B WILD-TYPE 270 176 231 276
'TMEM120B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S1082.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TMEM120B MUTATED 1 0 2 0 1 1
TMEM120B WILD-TYPE 274 136 204 134 86 119
'TMEM120B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1083.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TMEM120B MUTATED 1 1 0 0 1
TMEM120B WILD-TYPE 177 119 66 92 111
'TMEM120B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1084.  Gene #98: 'TMEM120B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TMEM120B MUTATED 2 1 0
TMEM120B WILD-TYPE 277 180 108
'LRIG2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S1085.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
LRIG2 MUTATED 0 0 3 1 0 0 0 0
LRIG2 WILD-TYPE 21 38 111 96 108 73 19 39
'LRIG2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0308 (Fisher's exact test), Q value = 0.42

Table S1086.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
LRIG2 MUTATED 3 0 0 1 0
LRIG2 WILD-TYPE 93 152 116 88 56

Figure S138.  Get High-res Image Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'LRIG2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.246 (Fisher's exact test), Q value = 0.91

Table S1087.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
LRIG2 MUTATED 3 1 0 2 1
LRIG2 WILD-TYPE 244 362 86 229 35
'LRIG2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.86

Table S1088.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
LRIG2 MUTATED 2 0 0 0 2 0
LRIG2 WILD-TYPE 126 96 156 107 107 52
'LRIG2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.86

Table S1089.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
LRIG2 MUTATED 1 3 0
LRIG2 WILD-TYPE 144 128 118
'LRIG2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S1090.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
LRIG2 MUTATED 0 0 1 0 3 0
LRIG2 WILD-TYPE 59 48 89 53 110 31
'LRIG2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.461 (Fisher's exact test), Q value = 1

Table S1091.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
LRIG2 MUTATED 4 3 0
LRIG2 WILD-TYPE 501 276 190
'LRIG2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.886 (Fisher's exact test), Q value = 1

Table S1092.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
LRIG2 MUTATED 2 1 0 2 1 1
LRIG2 WILD-TYPE 261 150 79 259 167 51
'LRIG2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.623 (Fisher's exact test), Q value = 1

Table S1093.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
LRIG2 MUTATED 3 0 2 2
LRIG2 WILD-TYPE 269 177 231 274
'LRIG2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S1094.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
LRIG2 MUTATED 4 0 2 0 0 1
LRIG2 WILD-TYPE 271 136 204 134 87 119
'LRIG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S1095.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
LRIG2 MUTATED 2 1 0 0 0
LRIG2 WILD-TYPE 176 119 66 92 112
'LRIG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1096.  Gene #99: 'LRIG2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
LRIG2 MUTATED 2 1 0
LRIG2 WILD-TYPE 277 180 108
'CCDC78 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.613 (Fisher's exact test), Q value = 1

Table S1097.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CCDC78 MUTATED 3 1 0 1 0
CCDC78 WILD-TYPE 244 362 86 230 36
'CCDC78 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S1098.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CCDC78 MUTATED 2 1 1 0 0 0
CCDC78 WILD-TYPE 126 95 155 107 109 52
'CCDC78 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S1099.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CCDC78 MUTATED 3 2 0
CCDC78 WILD-TYPE 502 277 190
'CCDC78 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S1100.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CCDC78 MUTATED 1 1 0 2 0 1
CCDC78 WILD-TYPE 262 150 79 259 168 51
'CCDC78 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 0.98

Table S1101.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CCDC78 MUTATED 1 0 3 1
CCDC78 WILD-TYPE 271 177 230 275
'CCDC78 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S1102.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CCDC78 MUTATED 3 1 1 0 0 0
CCDC78 WILD-TYPE 272 135 205 134 87 120
'CCDC78 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S1103.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CCDC78 MUTATED 3 1 0 0 1
CCDC78 WILD-TYPE 175 119 66 92 111
'CCDC78 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S1104.  Gene #100: 'CCDC78 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CCDC78 MUTATED 4 1 0
CCDC78 WILD-TYPE 275 180 108
'GAL3ST1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S1105.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GAL3ST1 MUTATED 2 1 0 2 0
GAL3ST1 WILD-TYPE 245 362 86 229 36
'GAL3ST1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S1106.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
GAL3ST1 MUTATED 1 0 0 1 1 0
GAL3ST1 WILD-TYPE 127 96 156 106 108 52
'GAL3ST1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1107.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GAL3ST1 MUTATED 3 1 1
GAL3ST1 WILD-TYPE 502 278 189
'GAL3ST1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S1108.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GAL3ST1 MUTATED 1 1 1 1 1 0
GAL3ST1 WILD-TYPE 262 150 78 260 167 52
'GAL3ST1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S1109.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GAL3ST1 MUTATED 2 2 1 0
GAL3ST1 WILD-TYPE 270 175 232 276
'GAL3ST1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S1110.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GAL3ST1 MUTATED 1 0 3 0 0 1
GAL3ST1 WILD-TYPE 274 136 203 134 87 119
'GAL3ST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.262 (Fisher's exact test), Q value = 0.92

Table S1111.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
GAL3ST1 MUTATED 0 1 0 0 2
GAL3ST1 WILD-TYPE 178 119 66 92 110
'GAL3ST1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S1112.  Gene #101: 'GAL3ST1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
GAL3ST1 MUTATED 1 2 0
GAL3ST1 WILD-TYPE 278 179 108
'FAM20C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.594 (Fisher's exact test), Q value = 1

Table S1113.  Gene #102: 'FAM20C MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
FAM20C MUTATED 1 1 1 1 0
FAM20C WILD-TYPE 246 362 85 230 36
'FAM20C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.419 (Fisher's exact test), Q value = 0.98

Table S1114.  Gene #102: 'FAM20C MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
FAM20C MUTATED 1 2 1
FAM20C WILD-TYPE 504 277 189
'FAM20C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S1115.  Gene #102: 'FAM20C MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
FAM20C MUTATED 1 0 0 1 1 1
FAM20C WILD-TYPE 262 151 79 260 167 51
'FAM20C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.127 (Fisher's exact test), Q value = 0.75

Table S1116.  Gene #102: 'FAM20C MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
FAM20C MUTATED 3 1 0 0
FAM20C WILD-TYPE 269 176 233 276
'FAM20C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.63 (Fisher's exact test), Q value = 1

Table S1117.  Gene #102: 'FAM20C MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
FAM20C MUTATED 2 0 0 1 0 1
FAM20C WILD-TYPE 273 136 206 133 87 119
'FAM20C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S1118.  Gene #102: 'FAM20C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
FAM20C MUTATED 0 1 0 1 1
FAM20C WILD-TYPE 178 119 66 91 111
'FAM20C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S1119.  Gene #102: 'FAM20C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
FAM20C MUTATED 1 1 1
FAM20C WILD-TYPE 278 180 107
'RCC1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S1120.  Gene #103: 'RCC1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RCC1 MUTATED 0 0 1 2 0 0 0 0
RCC1 WILD-TYPE 21 38 113 95 108 73 19 39
'RCC1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.112 (Fisher's exact test), Q value = 0.75

Table S1121.  Gene #103: 'RCC1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RCC1 MUTATED 1 0 0 2 0
RCC1 WILD-TYPE 95 152 116 87 56
'RCC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 0.8

Table S1122.  Gene #103: 'RCC1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RCC1 MUTATED 0 1 0 1 1
RCC1 WILD-TYPE 247 362 86 230 35
'RCC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.93

Table S1123.  Gene #103: 'RCC1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RCC1 MUTATED 1 2 0
RCC1 WILD-TYPE 504 277 190
'RCC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S1124.  Gene #103: 'RCC1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RCC1 MUTATED 0 0 0 1 2 0
RCC1 WILD-TYPE 263 151 79 260 166 52
'RCC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1125.  Gene #103: 'RCC1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RCC1 MUTATED 1 0 1 1
RCC1 WILD-TYPE 271 177 232 275
'RCC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.946 (Fisher's exact test), Q value = 1

Table S1126.  Gene #103: 'RCC1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RCC1 MUTATED 1 1 1 0 0 0
RCC1 WILD-TYPE 274 135 205 134 87 120
'CHD4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.88

Table S1127.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CHD4 MUTATED 0 2 0 2 2 1 1 1
CHD4 WILD-TYPE 21 36 114 95 106 72 18 38
'CHD4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 0.96

Table S1128.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CHD4 MUTATED 0 5 2 2 0
CHD4 WILD-TYPE 96 147 114 87 56
'CHD4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S1129.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CHD4 MUTATED 4 10 1 4 0
CHD4 WILD-TYPE 243 353 85 227 36
'CHD4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S1130.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CHD4 MUTATED 2 2 4 4 1 2
CHD4 WILD-TYPE 126 94 152 103 108 50
'CHD4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.197 (Fisher's exact test), Q value = 0.85

Table S1131.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CHD4 MUTATED 3 0 3
CHD4 WILD-TYPE 142 131 115
'CHD4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.98

Table S1132.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CHD4 MUTATED 0 0 2 2 1 1
CHD4 WILD-TYPE 59 48 88 51 112 30
'CHD4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S1133.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CHD4 MUTATED 8 6 5
CHD4 WILD-TYPE 497 273 185
'CHD4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 0.93

Table S1134.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CHD4 MUTATED 2 5 3 6 3 0
CHD4 WILD-TYPE 261 146 76 255 165 52
'CHD4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S1135.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CHD4 MUTATED 4 6 6 3
CHD4 WILD-TYPE 268 171 227 273
'CHD4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S1136.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CHD4 MUTATED 6 0 6 3 1 3
CHD4 WILD-TYPE 269 136 200 131 86 117
'CHD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.749 (Fisher's exact test), Q value = 1

Table S1137.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CHD4 MUTATED 3 1 2 2 3
CHD4 WILD-TYPE 175 119 64 90 109
'CHD4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.31 (Fisher's exact test), Q value = 0.93

Table S1138.  Gene #104: 'CHD4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CHD4 MUTATED 3 5 3
CHD4 WILD-TYPE 276 176 105
'STAG2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.284 (Fisher's exact test), Q value = 0.93

Table S1139.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
STAG2 MUTATED 0 0 0 1 3 2 1 0
STAG2 WILD-TYPE 21 38 114 96 105 71 18 39
'STAG2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 0.87

Table S1140.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
STAG2 MUTATED 0 1 3 1 2
STAG2 WILD-TYPE 96 151 113 88 54
'STAG2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S1141.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
STAG2 MUTATED 2 5 0 4 2
STAG2 WILD-TYPE 245 358 86 227 34
'STAG2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S1142.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
STAG2 MUTATED 4 1 2 0 2 0
STAG2 WILD-TYPE 124 95 154 107 107 52
'STAG2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S1143.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
STAG2 MUTATED 3 2 1
STAG2 WILD-TYPE 142 129 117
'STAG2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.226 (Fisher's exact test), Q value = 0.88

Table S1144.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
STAG2 MUTATED 2 0 2 1 0 1
STAG2 WILD-TYPE 57 48 88 52 113 30
'STAG2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 0.95

Table S1145.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
STAG2 MUTATED 6 6 1
STAG2 WILD-TYPE 499 273 189
'STAG2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S1146.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
STAG2 MUTATED 3 3 0 4 2 1
STAG2 WILD-TYPE 260 148 79 257 166 51
'STAG2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 0.92

Table S1147.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
STAG2 MUTATED 7 1 3 2
STAG2 WILD-TYPE 265 176 230 274
'STAG2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S1148.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
STAG2 MUTATED 4 3 1 2 1 2
STAG2 WILD-TYPE 271 133 205 132 86 118
'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.902 (Fisher's exact test), Q value = 1

Table S1149.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
STAG2 MUTATED 3 1 0 1 2
STAG2 WILD-TYPE 175 119 66 91 110
'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.685 (Fisher's exact test), Q value = 1

Table S1150.  Gene #105: 'STAG2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
STAG2 MUTATED 5 1 1
STAG2 WILD-TYPE 274 180 107
'HIST1H2BC MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.374 (Fisher's exact test), Q value = 0.98

Table S1151.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
HIST1H2BC MUTATED 0 0 0 1 1 1 1 0
HIST1H2BC WILD-TYPE 21 38 114 96 107 72 18 39
'HIST1H2BC MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0465 (Fisher's exact test), Q value = 0.54

Table S1152.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
HIST1H2BC MUTATED 0 0 3 0 1
HIST1H2BC WILD-TYPE 96 152 113 89 55

Figure S139.  Get High-res Image Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'HIST1H2BC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S1153.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
HIST1H2BC MUTATED 1 2 1 2 0
HIST1H2BC WILD-TYPE 246 361 85 229 36
'HIST1H2BC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 0.93

Table S1154.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
HIST1H2BC MUTATED 1 0 0 2 0 0
HIST1H2BC WILD-TYPE 127 96 156 105 109 52
'HIST1H2BC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 0.98

Table S1155.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
HIST1H2BC MUTATED 3 1 0
HIST1H2BC WILD-TYPE 142 130 118
'HIST1H2BC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1156.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
HIST1H2BC MUTATED 0 0 1 0 2 1
HIST1H2BC WILD-TYPE 59 48 89 53 111 30
'HIST1H2BC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0875 (Fisher's exact test), Q value = 0.68

Table S1157.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
HIST1H2BC MUTATED 1 4 1
HIST1H2BC WILD-TYPE 504 275 189
'HIST1H2BC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.847 (Fisher's exact test), Q value = 1

Table S1158.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
HIST1H2BC MUTATED 1 2 0 2 1 0
HIST1H2BC WILD-TYPE 262 149 79 259 167 52
'HIST1H2BC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.742 (Fisher's exact test), Q value = 1

Table S1159.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
HIST1H2BC MUTATED 1 2 1 2
HIST1H2BC WILD-TYPE 271 175 232 274
'HIST1H2BC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S1160.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
HIST1H2BC MUTATED 3 1 2 0 0 0
HIST1H2BC WILD-TYPE 272 135 204 134 87 120
'HIST1H2BC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.948 (Fisher's exact test), Q value = 1

Table S1161.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
HIST1H2BC MUTATED 2 1 0 0 1
HIST1H2BC WILD-TYPE 176 119 66 92 111
'HIST1H2BC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1162.  Gene #106: 'HIST1H2BC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
HIST1H2BC MUTATED 3 1 0
HIST1H2BC WILD-TYPE 276 180 108
'BPHL MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S1163.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
BPHL MUTATED 0 0 1 0 2 1 1 0
BPHL WILD-TYPE 21 38 113 97 106 72 18 39
'BPHL MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.467 (Fisher's exact test), Q value = 1

Table S1164.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
BPHL MUTATED 0 3 1 0 1
BPHL WILD-TYPE 96 149 115 89 55
'BPHL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.585 (Fisher's exact test), Q value = 1

Table S1165.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
BPHL MUTATED 1 1 1 2 0
BPHL WILD-TYPE 246 362 85 229 36
'BPHL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S1166.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
BPHL MUTATED 1 1 2
BPHL WILD-TYPE 144 130 116
'BPHL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.402 (Fisher's exact test), Q value = 0.98

Table S1167.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
BPHL MUTATED 1 0 0 1 1 1
BPHL WILD-TYPE 58 48 90 52 112 30
'BPHL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S1168.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
BPHL MUTATED 3 2 0
BPHL WILD-TYPE 502 277 190
'BPHL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.318 (Fisher's exact test), Q value = 0.94

Table S1169.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
BPHL MUTATED 1 0 0 3 0 1
BPHL WILD-TYPE 262 151 79 258 168 51
'BPHL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 0.84

Table S1170.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
BPHL MUTATED 0 0 2 3
BPHL WILD-TYPE 272 177 231 273
'BPHL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S1171.  Gene #107: 'BPHL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
BPHL MUTATED 2 1 0 1 1 0
BPHL WILD-TYPE 273 135 206 133 86 120
'ATP2A1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1172.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ATP2A1 MUTATED 0 0 1 1 1 0 0 0
ATP2A1 WILD-TYPE 21 38 113 96 107 73 19 39
'ATP2A1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S1173.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ATP2A1 MUTATED 0 2 0 1 0
ATP2A1 WILD-TYPE 96 150 116 88 56
'ATP2A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S1174.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ATP2A1 MUTATED 4 3 1 2 1
ATP2A1 WILD-TYPE 243 360 85 229 35
'ATP2A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.655 (Fisher's exact test), Q value = 1

Table S1175.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ATP2A1 MUTATED 3 2 2 0 2 0
ATP2A1 WILD-TYPE 125 94 154 107 107 52
'ATP2A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1176.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ATP2A1 MUTATED 6 3 2
ATP2A1 WILD-TYPE 499 276 188
'ATP2A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S1177.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ATP2A1 MUTATED 2 2 2 3 2 0
ATP2A1 WILD-TYPE 261 149 77 258 166 52
'ATP2A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1178.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ATP2A1 MUTATED 3 2 3 3
ATP2A1 WILD-TYPE 269 175 230 273
'ATP2A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.996 (Fisher's exact test), Q value = 1

Table S1179.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ATP2A1 MUTATED 4 2 2 1 1 1
ATP2A1 WILD-TYPE 271 134 204 133 86 119
'ATP2A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.979 (Fisher's exact test), Q value = 1

Table S1180.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ATP2A1 MUTATED 3 1 1 1 1
ATP2A1 WILD-TYPE 175 119 65 91 111
'ATP2A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S1181.  Gene #108: 'ATP2A1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ATP2A1 MUTATED 5 1 1
ATP2A1 WILD-TYPE 274 180 107
'LRRC37A3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.036 (Fisher's exact test), Q value = 0.47

Table S1182.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
LRRC37A3 MUTATED 0 2 0 0 0 1 0 1
LRRC37A3 WILD-TYPE 21 36 114 97 108 72 19 38

Figure S140.  Get High-res Image Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'LRRC37A3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.551 (Fisher's exact test), Q value = 1

Table S1183.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
LRRC37A3 MUTATED 0 3 1 0 0
LRRC37A3 WILD-TYPE 96 149 115 89 56
'LRRC37A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.79 (Fisher's exact test), Q value = 1

Table S1184.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
LRRC37A3 MUTATED 4 3 0 3 0
LRRC37A3 WILD-TYPE 243 360 86 228 36
'LRRC37A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.853 (Fisher's exact test), Q value = 1

Table S1185.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
LRRC37A3 MUTATED 1 1 1 2 2 1
LRRC37A3 WILD-TYPE 127 95 155 105 107 51
'LRRC37A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S1186.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
LRRC37A3 MUTATED 1 0 2
LRRC37A3 WILD-TYPE 144 131 116
'LRRC37A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S1187.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
LRRC37A3 MUTATED 0 0 0 1 2 0
LRRC37A3 WILD-TYPE 59 48 90 52 111 31
'LRRC37A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1188.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
LRRC37A3 MUTATED 5 3 2
LRRC37A3 WILD-TYPE 500 276 188
'LRRC37A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.615 (Fisher's exact test), Q value = 1

Table S1189.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
LRRC37A3 MUTATED 1 2 0 4 3 0
LRRC37A3 WILD-TYPE 262 149 79 257 165 52
'LRRC37A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S1190.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
LRRC37A3 MUTATED 3 3 1 3
LRRC37A3 WILD-TYPE 269 174 232 273
'LRRC37A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.93

Table S1191.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
LRRC37A3 MUTATED 2 1 1 3 0 3
LRRC37A3 WILD-TYPE 273 135 205 131 87 117
'LRRC37A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.356 (Fisher's exact test), Q value = 0.96

Table S1192.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
LRRC37A3 MUTATED 1 3 0 0 2
LRRC37A3 WILD-TYPE 177 117 66 92 110
'LRRC37A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S1193.  Gene #109: 'LRRC37A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
LRRC37A3 MUTATED 4 2 0
LRRC37A3 WILD-TYPE 275 179 108
'EPDR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.93

Table S1194.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
EPDR1 MUTATED 0 1 1 0 0 2 0 0
EPDR1 WILD-TYPE 21 37 113 97 108 71 19 39
'EPDR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.82 (Fisher's exact test), Q value = 1

Table S1195.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
EPDR1 MUTATED 1 1 2 0 0
EPDR1 WILD-TYPE 95 151 114 89 56
'EPDR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S1196.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
EPDR1 MUTATED 2 1 0 2 0
EPDR1 WILD-TYPE 245 362 86 229 36
'EPDR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S1197.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
EPDR1 MUTATED 2 2 0
EPDR1 WILD-TYPE 143 129 118
'EPDR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S1198.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
EPDR1 MUTATED 1 0 0 0 2 1
EPDR1 WILD-TYPE 58 48 90 53 111 30
'EPDR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S1199.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
EPDR1 MUTATED 3 2 0
EPDR1 WILD-TYPE 502 277 190
'EPDR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S1200.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
EPDR1 MUTATED 1 1 0 2 0 1
EPDR1 WILD-TYPE 262 150 79 259 168 51
'EPDR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.775 (Fisher's exact test), Q value = 1

Table S1201.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
EPDR1 MUTATED 1 0 2 1
EPDR1 WILD-TYPE 271 177 231 275
'EPDR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S1202.  Gene #110: 'EPDR1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
EPDR1 MUTATED 1 2 1 0 0 0
EPDR1 WILD-TYPE 274 134 205 134 87 120
'EXOC4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0113 (Fisher's exact test), Q value = 0.23

Table S1203.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
EXOC4 MUTATED 0 2 0 0 0 1 1 0
EXOC4 WILD-TYPE 21 36 114 97 108 72 18 39

Figure S141.  Get High-res Image Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'EXOC4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S1204.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
EXOC4 MUTATED 0 2 2 0 0
EXOC4 WILD-TYPE 96 150 114 89 56
'EXOC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S1205.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
EXOC4 MUTATED 3 2 0 3 0
EXOC4 WILD-TYPE 244 361 86 228 36
'EXOC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.145 (Fisher's exact test), Q value = 0.77

Table S1206.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
EXOC4 MUTATED 3 2 0 1 0 1
EXOC4 WILD-TYPE 125 94 156 106 109 51
'EXOC4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0351 (Fisher's exact test), Q value = 0.47

Table S1207.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
EXOC4 MUTATED 1 5 2
EXOC4 WILD-TYPE 504 274 188

Figure S142.  Get High-res Image Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'EXOC4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.029 (Fisher's exact test), Q value = 0.4

Table S1208.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
EXOC4 MUTATED 0 2 1 3 0 2
EXOC4 WILD-TYPE 263 149 78 258 168 50

Figure S143.  Get High-res Image Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'EXOC4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S1209.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
EXOC4 MUTATED 3 2 1 2
EXOC4 WILD-TYPE 269 175 232 274
'EXOC4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.745 (Fisher's exact test), Q value = 1

Table S1210.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
EXOC4 MUTATED 2 2 3 1 0 0
EXOC4 WILD-TYPE 273 134 203 133 87 120
'EXOC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.625 (Fisher's exact test), Q value = 1

Table S1211.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
EXOC4 MUTATED 2 0 0 1 2
EXOC4 WILD-TYPE 176 120 66 91 110
'EXOC4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.418 (Fisher's exact test), Q value = 0.98

Table S1212.  Gene #111: 'EXOC4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
EXOC4 MUTATED 2 3 0
EXOC4 WILD-TYPE 277 178 108
'C11ORF49 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.75

Table S1213.  Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
C11ORF49 MUTATED 0 2 1 1 1
C11ORF49 WILD-TYPE 247 361 85 230 35
'C11ORF49 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S1214.  Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
C11ORF49 MUTATED 1 0 0 1 2 0
C11ORF49 WILD-TYPE 127 96 156 106 107 52
'C11ORF49 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00226 (Fisher's exact test), Q value = 0.069

Table S1215.  Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
C11ORF49 MUTATED 0 5 0
C11ORF49 WILD-TYPE 505 274 190

Figure S144.  Get High-res Image Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'C11ORF49 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0254 (Fisher's exact test), Q value = 0.39

Table S1216.  Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
C11ORF49 MUTATED 0 1 0 0 3 1
C11ORF49 WILD-TYPE 263 150 79 261 165 51

Figure S145.  Get High-res Image Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'C11ORF49 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.75

Table S1217.  Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
C11ORF49 MUTATED 4 0 0 1
C11ORF49 WILD-TYPE 268 177 233 275
'C11ORF49 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0693 (Fisher's exact test), Q value = 0.62

Table S1218.  Gene #112: 'C11ORF49 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
C11ORF49 MUTATED 2 0 0 0 0 3
C11ORF49 WILD-TYPE 273 136 206 134 87 117
'SARM1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S1219.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SARM1 MUTATED 0 0 0 3 1 1 0 0
SARM1 WILD-TYPE 21 38 114 94 107 72 19 39
'SARM1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.116 (Fisher's exact test), Q value = 0.75

Table S1220.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SARM1 MUTATED 1 0 1 3 0
SARM1 WILD-TYPE 95 152 115 86 56
'SARM1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S1221.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SARM1 MUTATED 3 2 0 1 0
SARM1 WILD-TYPE 244 361 86 230 36
'SARM1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S1222.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
SARM1 MUTATED 2 0 1
SARM1 WILD-TYPE 143 131 117
'SARM1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.13 (Fisher's exact test), Q value = 0.75

Table S1223.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
SARM1 MUTATED 0 0 3 0 0 0
SARM1 WILD-TYPE 59 48 87 53 113 31
'SARM1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0252 (Fisher's exact test), Q value = 0.39

Table S1224.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SARM1 MUTATED 1 5 0
SARM1 WILD-TYPE 504 274 190

Figure S146.  Get High-res Image Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'SARM1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0198 (Fisher's exact test), Q value = 0.33

Table S1225.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SARM1 MUTATED 0 3 0 0 3 0
SARM1 WILD-TYPE 263 148 79 261 165 52

Figure S147.  Get High-res Image Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'SARM1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S1226.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SARM1 MUTATED 3 1 1 1
SARM1 WILD-TYPE 269 176 232 275
'SARM1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.33 (Fisher's exact test), Q value = 0.94

Table S1227.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SARM1 MUTATED 3 1 0 0 0 2
SARM1 WILD-TYPE 272 135 206 134 87 118
'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.54 (Fisher's exact test), Q value = 1

Table S1228.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SARM1 MUTATED 1 2 0 0 0
SARM1 WILD-TYPE 177 118 66 92 112
'SARM1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.93

Table S1229.  Gene #113: 'SARM1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SARM1 MUTATED 3 0 0
SARM1 WILD-TYPE 276 181 108
'SP3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S1230.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SP3 MUTATED 0 0 1 0 2 1 0 0
SP3 WILD-TYPE 21 38 113 97 106 72 19 39
'SP3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S1231.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SP3 MUTATED 0 3 1 0 0
SP3 WILD-TYPE 96 149 115 89 56
'SP3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S1232.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SP3 MUTATED 2 3 1 0 0
SP3 WILD-TYPE 245 360 85 231 36
'SP3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S1233.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
SP3 MUTATED 1 0 2 1 0 0
SP3 WILD-TYPE 127 96 154 106 109 52
'SP3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S1234.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SP3 MUTATED 3 2 2
SP3 WILD-TYPE 502 277 188
'SP3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.442 (Fisher's exact test), Q value = 1

Table S1235.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SP3 MUTATED 1 2 0 4 0 0
SP3 WILD-TYPE 262 149 79 257 168 52
'SP3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.395 (Fisher's exact test), Q value = 0.98

Table S1236.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SP3 MUTATED 1 0 3 3
SP3 WILD-TYPE 271 177 230 273
'SP3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.411 (Fisher's exact test), Q value = 0.98

Table S1237.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SP3 MUTATED 3 2 0 1 1 0
SP3 WILD-TYPE 272 134 206 133 86 120
'SP3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.93

Table S1238.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SP3 MUTATED 1 0 1 0 2
SP3 WILD-TYPE 177 120 65 92 110
'SP3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1239.  Gene #114: 'SP3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SP3 MUTATED 2 1 1
SP3 WILD-TYPE 277 180 107
'ACTG1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S1240.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ACTG1 MUTATED 0 1 0 0 2 0 0 0
ACTG1 WILD-TYPE 21 37 114 97 106 73 19 39
'ACTG1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.395 (Fisher's exact test), Q value = 0.98

Table S1241.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ACTG1 MUTATED 0 2 0 0 1
ACTG1 WILD-TYPE 96 150 116 89 55
'ACTG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.891 (Fisher's exact test), Q value = 1

Table S1242.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ACTG1 MUTATED 1 4 0 2 0
ACTG1 WILD-TYPE 246 359 86 229 36
'ACTG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 0.78

Table S1243.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ACTG1 MUTATED 0 1 1 0 3 1
ACTG1 WILD-TYPE 128 95 155 107 106 51
'ACTG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.709 (Fisher's exact test), Q value = 1

Table S1244.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ACTG1 MUTATED 3 3 2
ACTG1 WILD-TYPE 502 276 188
'ACTG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.425 (Fisher's exact test), Q value = 0.98

Table S1245.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ACTG1 MUTATED 3 0 1 1 3 0
ACTG1 WILD-TYPE 260 151 78 260 165 52
'ACTG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.93

Table S1246.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ACTG1 MUTATED 2 2 0 4
ACTG1 WILD-TYPE 270 175 233 272
'ACTG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S1247.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ACTG1 MUTATED 1 1 3 1 0 2
ACTG1 WILD-TYPE 274 135 203 133 87 118
'ACTG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.146 (Fisher's exact test), Q value = 0.77

Table S1248.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ACTG1 MUTATED 0 3 0 1 2
ACTG1 WILD-TYPE 178 117 66 91 110
'ACTG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1249.  Gene #115: 'ACTG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ACTG1 MUTATED 3 2 1
ACTG1 WILD-TYPE 276 179 107
'ANXA11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S1250.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ANXA11 MUTATED 0 0 1 0 1 0 0 1
ANXA11 WILD-TYPE 21 38 113 97 107 73 19 38
'ANXA11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.493 (Fisher's exact test), Q value = 1

Table S1251.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ANXA11 MUTATED 1 1 0 0 1
ANXA11 WILD-TYPE 95 151 116 89 55
'ANXA11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 0.98

Table S1252.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ANXA11 MUTATED 0 1 1 1 0
ANXA11 WILD-TYPE 247 362 85 230 36
'ANXA11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0628 (Fisher's exact test), Q value = 0.6

Table S1253.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ANXA11 MUTATED 0 3 0
ANXA11 WILD-TYPE 145 128 118
'ANXA11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.632 (Fisher's exact test), Q value = 1

Table S1254.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ANXA11 MUTATED 1 1 0 0 1 0
ANXA11 WILD-TYPE 58 47 90 53 112 31
'ANXA11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S1255.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ANXA11 MUTATED 2 0 1
ANXA11 WILD-TYPE 503 279 189
'ANXA11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.858 (Fisher's exact test), Q value = 1

Table S1256.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ANXA11 MUTATED 2 0 0 1 0 0
ANXA11 WILD-TYPE 261 151 79 260 168 52
'ANXA11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.183 (Fisher's exact test), Q value = 0.84

Table S1257.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ANXA11 MUTATED 0 1 2 0
ANXA11 WILD-TYPE 272 176 231 276
'ANXA11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.271 (Fisher's exact test), Q value = 0.93

Table S1258.  Gene #116: 'ANXA11 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ANXA11 MUTATED 1 0 0 2 0 0
ANXA11 WILD-TYPE 274 136 206 132 87 120
'OR8D1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S1259.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
OR8D1 MUTATED 0 0 0 2 2 0 0 0
OR8D1 WILD-TYPE 21 38 114 95 106 73 19 39
'OR8D1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00883 (Fisher's exact test), Q value = 0.2

Table S1260.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
OR8D1 MUTATED 0 0 0 2 2
OR8D1 WILD-TYPE 96 152 116 87 54

Figure S148.  Get High-res Image Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'OR8D1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S1261.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
OR8D1 MUTATED 0 3 0 1 0
OR8D1 WILD-TYPE 247 360 86 230 36
'OR8D1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.865 (Fisher's exact test), Q value = 1

Table S1262.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
OR8D1 MUTATED 1 0 1 1 2 0
OR8D1 WILD-TYPE 127 96 155 106 107 52
'OR8D1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1263.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
OR8D1 MUTATED 1 2 1
OR8D1 WILD-TYPE 144 129 117
'OR8D1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.795 (Fisher's exact test), Q value = 1

Table S1264.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
OR8D1 MUTATED 0 0 2 0 2 0
OR8D1 WILD-TYPE 59 48 88 53 111 31
'OR8D1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.337 (Fisher's exact test), Q value = 0.95

Table S1265.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
OR8D1 MUTATED 2 3 0
OR8D1 WILD-TYPE 503 276 190
'OR8D1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.182 (Fisher's exact test), Q value = 0.84

Table S1266.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
OR8D1 MUTATED 2 0 0 0 3 0
OR8D1 WILD-TYPE 261 151 79 261 165 52
'OR8D1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S1267.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
OR8D1 MUTATED 1 0 2 1
OR8D1 WILD-TYPE 271 177 231 275
'OR8D1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S1268.  Gene #117: 'OR8D1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
OR8D1 MUTATED 1 0 1 0 1 1
OR8D1 WILD-TYPE 274 136 205 134 86 119
'GYLTL1B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.419 (Fisher's exact test), Q value = 0.98

Table S1269.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
GYLTL1B MUTATED 1 0 0 1 1 1 0 0
GYLTL1B WILD-TYPE 20 38 114 96 107 72 19 39
'GYLTL1B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1270.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
GYLTL1B MUTATED 0 1 1 1 1
GYLTL1B WILD-TYPE 96 151 115 88 55
'GYLTL1B MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1271.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GYLTL1B MUTATED 1 2 0 1 0
GYLTL1B WILD-TYPE 246 361 86 230 36
'GYLTL1B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S1272.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
GYLTL1B MUTATED 1 1 2
GYLTL1B WILD-TYPE 144 130 116
'GYLTL1B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 0.96

Table S1273.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
GYLTL1B MUTATED 0 1 2 1 0 0
GYLTL1B WILD-TYPE 59 47 88 52 113 31
'GYLTL1B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S1274.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GYLTL1B MUTATED 2 2 0
GYLTL1B WILD-TYPE 503 277 190
'GYLTL1B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.447 (Fisher's exact test), Q value = 1

Table S1275.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GYLTL1B MUTATED 1 2 0 0 1 0
GYLTL1B WILD-TYPE 262 149 79 261 167 52
'GYLTL1B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.315 (Fisher's exact test), Q value = 0.93

Table S1276.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GYLTL1B MUTATED 2 0 2 0
GYLTL1B WILD-TYPE 270 177 231 276
'GYLTL1B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.409 (Fisher's exact test), Q value = 0.98

Table S1277.  Gene #118: 'GYLTL1B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GYLTL1B MUTATED 1 1 0 0 1 1
GYLTL1B WILD-TYPE 274 135 206 134 86 119
'ANGPTL6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.751 (Fisher's exact test), Q value = 1

Table S1278.  Gene #119: 'ANGPTL6 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ANGPTL6 MUTATED 0 2 0 1 0
ANGPTL6 WILD-TYPE 247 361 86 230 36
'ANGPTL6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S1279.  Gene #119: 'ANGPTL6 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ANGPTL6 MUTATED 1 1 1
ANGPTL6 WILD-TYPE 504 278 189
'ANGPTL6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.617 (Fisher's exact test), Q value = 1

Table S1280.  Gene #119: 'ANGPTL6 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ANGPTL6 MUTATED 0 0 0 2 1 0
ANGPTL6 WILD-TYPE 263 151 79 259 167 52
'PFKP MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 0.98

Table S1281.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
PFKP MUTATED 0 0 3 3 0 0 0 0
PFKP WILD-TYPE 21 38 111 94 108 73 19 39
'PFKP MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0135 (Fisher's exact test), Q value = 0.26

Table S1282.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
PFKP MUTATED 3 0 0 3 0
PFKP WILD-TYPE 93 152 116 86 56

Figure S149.  Get High-res Image Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'PFKP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.233 (Fisher's exact test), Q value = 0.88

Table S1283.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PFKP MUTATED 2 1 0 3 1
PFKP WILD-TYPE 245 362 86 228 35
'PFKP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.056 (Fisher's exact test), Q value = 0.59

Table S1284.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PFKP MUTATED 3 0 0 0 0 0
PFKP WILD-TYPE 125 96 156 107 109 52
'PFKP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.93

Table S1285.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
PFKP MUTATED 3 0 2
PFKP WILD-TYPE 142 131 116
'PFKP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S1286.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
PFKP MUTATED 0 0 3 0 2 0
PFKP WILD-TYPE 59 48 87 53 111 31
'PFKP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.461 (Fisher's exact test), Q value = 1

Table S1287.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PFKP MUTATED 4 3 0
PFKP WILD-TYPE 501 276 190
'PFKP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.277 (Fisher's exact test), Q value = 0.93

Table S1288.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PFKP MUTATED 3 1 0 0 3 0
PFKP WILD-TYPE 260 150 79 261 165 52
'PFKP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 0.75

Table S1289.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PFKP MUTATED 5 0 1 1
PFKP WILD-TYPE 267 177 232 275
'PFKP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 0.86

Table S1290.  Gene #120: 'PFKP MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PFKP MUTATED 3 0 1 0 0 3
PFKP WILD-TYPE 272 136 205 134 87 117
'SPTAN1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.788 (Fisher's exact test), Q value = 1

Table S1291.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SPTAN1 MUTATED 0 0 0 2 2 1 0 0
SPTAN1 WILD-TYPE 21 38 114 95 106 72 19 39
'SPTAN1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S1292.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SPTAN1 MUTATED 0 2 1 2 0
SPTAN1 WILD-TYPE 96 150 115 87 56
'SPTAN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.32 (Fisher's exact test), Q value = 0.94

Table S1293.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SPTAN1 MUTATED 2 2 1 4 1
SPTAN1 WILD-TYPE 245 361 85 227 35
'SPTAN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1294.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
SPTAN1 MUTATED 1 2 1 2 2 1
SPTAN1 WILD-TYPE 127 94 155 105 107 51
'SPTAN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.111 (Fisher's exact test), Q value = 0.75

Table S1295.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
SPTAN1 MUTATED 3 0 0
SPTAN1 WILD-TYPE 142 131 118
'SPTAN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.78

Table S1296.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
SPTAN1 MUTATED 0 0 2 0 0 1
SPTAN1 WILD-TYPE 59 48 88 53 113 30
'SPTAN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.056 (Fisher's exact test), Q value = 0.59

Table S1297.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SPTAN1 MUTATED 3 7 1
SPTAN1 WILD-TYPE 502 272 189
'SPTAN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.498 (Fisher's exact test), Q value = 1

Table S1298.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SPTAN1 MUTATED 2 2 0 2 4 1
SPTAN1 WILD-TYPE 261 149 79 259 164 51
'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.706 (Fisher's exact test), Q value = 1

Table S1299.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SPTAN1 MUTATED 3 1 2 5
SPTAN1 WILD-TYPE 269 176 231 271
'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.231 (Fisher's exact test), Q value = 0.88

Table S1300.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SPTAN1 MUTATED 5 1 0 1 1 3
SPTAN1 WILD-TYPE 270 135 206 133 86 117
'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.344 (Fisher's exact test), Q value = 0.96

Table S1301.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SPTAN1 MUTATED 2 4 1 0 1
SPTAN1 WILD-TYPE 176 116 65 92 111
'SPTAN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.137 (Fisher's exact test), Q value = 0.76

Table S1302.  Gene #121: 'SPTAN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SPTAN1 MUTATED 7 1 0
SPTAN1 WILD-TYPE 272 180 108
'LIFR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 0.94

Table S1303.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
LIFR MUTATED 0 0 0 0 2 2 0 1
LIFR WILD-TYPE 21 38 114 97 106 71 19 38
'LIFR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S1304.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
LIFR MUTATED 0 3 2 0 0
LIFR WILD-TYPE 96 149 114 89 56
'LIFR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.79

Table S1305.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
LIFR MUTATED 0 5 1 2 1
LIFR WILD-TYPE 247 358 85 229 35
'LIFR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S1306.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
LIFR MUTATED 1 1 1 2 1 1
LIFR WILD-TYPE 127 95 155 105 108 51
'LIFR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.00754 (Fisher's exact test), Q value = 0.17

Table S1307.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
LIFR MUTATED 0 0 4
LIFR WILD-TYPE 145 131 114

Figure S150.  Get High-res Image Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

'LIFR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0165 (Fisher's exact test), Q value = 0.29

Table S1308.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
LIFR MUTATED 0 2 0 2 0 0
LIFR WILD-TYPE 59 46 90 51 113 31

Figure S151.  Get High-res Image Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

'LIFR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1309.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
LIFR MUTATED 5 2 2
LIFR WILD-TYPE 500 277 188
'LIFR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.068 (Fisher's exact test), Q value = 0.62

Table S1310.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
LIFR MUTATED 0 3 2 2 1 1
LIFR WILD-TYPE 263 148 77 259 167 51
'LIFR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S1311.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
LIFR MUTATED 1 3 3 2
LIFR WILD-TYPE 271 174 230 274
'LIFR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S1312.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
LIFR MUTATED 4 1 1 2 0 1
LIFR WILD-TYPE 271 135 205 132 87 119
'LIFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S1313.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
LIFR MUTATED 1 1 1 0 0
LIFR WILD-TYPE 177 119 65 92 112
'LIFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1314.  Gene #122: 'LIFR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
LIFR MUTATED 2 1 0
LIFR WILD-TYPE 277 180 108
'TTPAL MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 0.9

Table S1315.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TTPAL MUTATED 0 1 0 2 0 0 0 0
TTPAL WILD-TYPE 21 37 114 95 108 73 19 39
'TTPAL MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.302 (Fisher's exact test), Q value = 0.93

Table S1316.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TTPAL MUTATED 0 1 0 2 0
TTPAL WILD-TYPE 96 151 116 87 56
'TTPAL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 0.78

Table S1317.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TTPAL MUTATED 1 0 0 3 0
TTPAL WILD-TYPE 246 363 86 228 36
'TTPAL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S1318.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TTPAL MUTATED 2 0 1
TTPAL WILD-TYPE 143 131 117
'TTPAL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1319.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TTPAL MUTATED 0 0 2 0 1 0
TTPAL WILD-TYPE 59 48 88 53 112 31
'TTPAL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0497 (Fisher's exact test), Q value = 0.56

Table S1320.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TTPAL MUTATED 0 3 1
TTPAL WILD-TYPE 505 276 189

Figure S152.  Get High-res Image Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'TTPAL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.98

Table S1321.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TTPAL MUTATED 0 0 0 2 2 0
TTPAL WILD-TYPE 263 151 79 259 166 52
'TTPAL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S1322.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TTPAL MUTATED 2 0 0 2
TTPAL WILD-TYPE 270 177 233 274
'TTPAL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0869 (Fisher's exact test), Q value = 0.68

Table S1323.  Gene #123: 'TTPAL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TTPAL MUTATED 0 1 0 1 0 2
TTPAL WILD-TYPE 275 135 206 133 87 118
'HCFC2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.031 (Fisher's exact test), Q value = 0.42

Table S1324.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
HCFC2 MUTATED 1 0 1 0 0 0 1 1
HCFC2 WILD-TYPE 20 38 113 97 108 73 18 38

Figure S153.  Get High-res Image Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'HCFC2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S1325.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
HCFC2 MUTATED 0 3 1 0 0
HCFC2 WILD-TYPE 96 149 115 89 56
'HCFC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.76

Table S1326.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
HCFC2 MUTATED 1 4 1 2 2
HCFC2 WILD-TYPE 246 359 85 229 34
'HCFC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S1327.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
HCFC2 MUTATED 3 1 2 1 1 0
HCFC2 WILD-TYPE 125 95 154 106 108 52
'HCFC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0143 (Fisher's exact test), Q value = 0.26

Table S1328.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
HCFC2 MUTATED 1 5 4
HCFC2 WILD-TYPE 504 274 186

Figure S154.  Get High-res Image Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'HCFC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.246 (Fisher's exact test), Q value = 0.91

Table S1329.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
HCFC2 MUTATED 1 3 2 2 1 1
HCFC2 WILD-TYPE 262 148 77 259 167 51
'HCFC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S1330.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
HCFC2 MUTATED 3 2 1 4
HCFC2 WILD-TYPE 269 175 232 272
'HCFC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.985 (Fisher's exact test), Q value = 1

Table S1331.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
HCFC2 MUTATED 3 1 2 2 1 1
HCFC2 WILD-TYPE 272 135 204 132 86 119
'HCFC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S1332.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
HCFC2 MUTATED 4 1 0 0 2
HCFC2 WILD-TYPE 174 119 66 92 110
'HCFC2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S1333.  Gene #124: 'HCFC2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
HCFC2 MUTATED 5 2 0
HCFC2 WILD-TYPE 274 179 108
'OR6C76 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 0.93

Table S1334.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
OR6C76 MUTATED 0 0 0 1 2 0 1 0
OR6C76 WILD-TYPE 21 38 114 96 106 73 18 39
'OR6C76 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 0.96

Table S1335.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
OR6C76 MUTATED 0 3 0 1 0
OR6C76 WILD-TYPE 96 149 116 88 56
'OR6C76 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 0.98

Table S1336.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
OR6C76 MUTATED 1 4 1 0 0
OR6C76 WILD-TYPE 246 359 85 231 36
'OR6C76 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S1337.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
OR6C76 MUTATED 1 1 2 1 0 0
OR6C76 WILD-TYPE 127 95 154 106 109 52
'OR6C76 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1338.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
OR6C76 MUTATED 1 2 0
OR6C76 WILD-TYPE 144 129 118
'OR6C76 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S1339.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
OR6C76 MUTATED 1 1 1 0 0 0
OR6C76 WILD-TYPE 58 47 89 53 113 31
'OR6C76 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S1340.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
OR6C76 MUTATED 3 2 2
OR6C76 WILD-TYPE 502 277 188
'OR6C76 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.622 (Fisher's exact test), Q value = 1

Table S1341.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
OR6C76 MUTATED 1 1 1 2 1 1
OR6C76 WILD-TYPE 262 150 78 259 167 51
'OR6C76 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S1342.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
OR6C76 MUTATED 2 2 1 2
OR6C76 WILD-TYPE 270 175 232 274
'OR6C76 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.808 (Fisher's exact test), Q value = 1

Table S1343.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
OR6C76 MUTATED 1 2 2 1 0 1
OR6C76 WILD-TYPE 274 134 204 133 87 119
'OR6C76 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.156 (Fisher's exact test), Q value = 0.78

Table S1344.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
OR6C76 MUTATED 1 0 0 0 3
OR6C76 WILD-TYPE 177 120 66 92 109
'OR6C76 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.254 (Fisher's exact test), Q value = 0.92

Table S1345.  Gene #125: 'OR6C76 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
OR6C76 MUTATED 1 3 0
OR6C76 WILD-TYPE 278 178 108
'ACOT2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.84

Table S1346.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ACOT2 MUTATED 0 2 0 1 1 0 0 0
ACOT2 WILD-TYPE 21 36 114 96 107 73 19 39
'ACOT2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 0.96

Table S1347.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ACOT2 MUTATED 0 3 0 1 0
ACOT2 WILD-TYPE 96 149 116 88 56
'ACOT2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 0.98

Table S1348.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ACOT2 MUTATED 3 2 0 0 0
ACOT2 WILD-TYPE 244 361 86 231 36
'ACOT2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S1349.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ACOT2 MUTATED 0 1 1 1 0 1
ACOT2 WILD-TYPE 128 95 155 106 109 51
'ACOT2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.496 (Fisher's exact test), Q value = 1

Table S1350.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ACOT2 MUTATED 2 1 2
ACOT2 WILD-TYPE 503 278 188
'ACOT2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.74 (Fisher's exact test), Q value = 1

Table S1351.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ACOT2 MUTATED 1 0 1 2 1 0
ACOT2 WILD-TYPE 262 151 78 259 167 52
'ACOT2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0162 (Fisher's exact test), Q value = 0.28

Table S1352.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ACOT2 MUTATED 0 3 2 0
ACOT2 WILD-TYPE 272 174 231 276

Figure S155.  Get High-res Image Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

'ACOT2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.636 (Fisher's exact test), Q value = 1

Table S1353.  Gene #126: 'ACOT2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ACOT2 MUTATED 1 1 1 2 0 0
ACOT2 WILD-TYPE 274 135 205 132 87 120
'KIAA0430 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S1354.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
KIAA0430 MUTATED 0 1 3 1 1 1 1 0
KIAA0430 WILD-TYPE 21 37 111 96 107 72 18 39
'KIAA0430 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S1355.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
KIAA0430 MUTATED 3 2 2 1 0
KIAA0430 WILD-TYPE 93 150 114 88 56
'KIAA0430 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.75

Table S1356.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
KIAA0430 MUTATED 7 3 3 2 0
KIAA0430 WILD-TYPE 240 360 83 229 36
'KIAA0430 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.109 (Fisher's exact test), Q value = 0.75

Table S1357.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
KIAA0430 MUTATED 3 0 1 1 2 3
KIAA0430 WILD-TYPE 125 96 155 106 107 49
'KIAA0430 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.93

Table S1358.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
KIAA0430 MUTATED 3 0 1
KIAA0430 WILD-TYPE 142 131 117
'KIAA0430 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1359.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
KIAA0430 MUTATED 0 0 1 0 3 0
KIAA0430 WILD-TYPE 59 48 89 53 110 31
'KIAA0430 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.835 (Fisher's exact test), Q value = 1

Table S1360.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
KIAA0430 MUTATED 8 5 2
KIAA0430 WILD-TYPE 497 274 188
'KIAA0430 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.862 (Fisher's exact test), Q value = 1

Table S1361.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
KIAA0430 MUTATED 3 4 1 4 3 0
KIAA0430 WILD-TYPE 260 147 78 257 165 52
'KIAA0430 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1362.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
KIAA0430 MUTATED 4 3 4 4
KIAA0430 WILD-TYPE 268 174 229 272
'KIAA0430 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S1363.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
KIAA0430 MUTATED 7 1 2 1 2 2
KIAA0430 WILD-TYPE 268 135 204 133 85 118
'KIAA0430 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.78

Table S1364.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
KIAA0430 MUTATED 1 3 2 2 0
KIAA0430 WILD-TYPE 177 117 64 90 112
'KIAA0430 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S1365.  Gene #127: 'KIAA0430 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
KIAA0430 MUTATED 5 1 2
KIAA0430 WILD-TYPE 274 180 106
'SEC14L5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.214 (Fisher's exact test), Q value = 0.87

Table S1366.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SEC14L5 MUTATED 0 0 1 4 0 0 0 0
SEC14L5 WILD-TYPE 21 38 113 93 108 73 19 39
'SEC14L5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00238 (Fisher's exact test), Q value = 0.071

Table S1367.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SEC14L5 MUTATED 0 0 0 4 1
SEC14L5 WILD-TYPE 96 152 116 85 55

Figure S156.  Get High-res Image Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'SEC14L5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.93

Table S1368.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SEC14L5 MUTATED 0 3 0 4 0
SEC14L5 WILD-TYPE 247 360 86 227 36
'SEC14L5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S1369.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
SEC14L5 MUTATED 0 1 0 1 1 0
SEC14L5 WILD-TYPE 128 95 156 106 108 52
'SEC14L5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.395 (Fisher's exact test), Q value = 0.98

Table S1370.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
SEC14L5 MUTATED 3 1 0
SEC14L5 WILD-TYPE 142 130 118
'SEC14L5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.208 (Fisher's exact test), Q value = 0.86

Table S1371.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
SEC14L5 MUTATED 1 0 3 0 0 0
SEC14L5 WILD-TYPE 58 48 87 53 113 31
'SEC14L5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0525 (Fisher's exact test), Q value = 0.58

Table S1372.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SEC14L5 MUTATED 2 5 0
SEC14L5 WILD-TYPE 503 274 190
'SEC14L5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0883 (Fisher's exact test), Q value = 0.68

Table S1373.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SEC14L5 MUTATED 1 0 0 1 4 1
SEC14L5 WILD-TYPE 262 151 79 260 164 51
'SEC14L5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.115 (Fisher's exact test), Q value = 0.75

Table S1374.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SEC14L5 MUTATED 5 0 1 1
SEC14L5 WILD-TYPE 267 177 232 275
'SEC14L5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.243 (Fisher's exact test), Q value = 0.91

Table S1375.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SEC14L5 MUTATED 1 1 2 0 0 3
SEC14L5 WILD-TYPE 274 135 204 134 87 117
'SEC14L5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.29 (Fisher's exact test), Q value = 0.93

Table S1376.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SEC14L5 MUTATED 0 2 0 0 1
SEC14L5 WILD-TYPE 178 118 66 92 111
'SEC14L5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1377.  Gene #128: 'SEC14L5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SEC14L5 MUTATED 2 1 0
SEC14L5 WILD-TYPE 277 180 108
'GTF2IRD2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S1378.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
GTF2IRD2 MUTATED 0 1 1 1 1 1 0 2
GTF2IRD2 WILD-TYPE 21 37 113 96 107 72 19 37
'GTF2IRD2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S1379.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
GTF2IRD2 MUTATED 1 3 1 1 1
GTF2IRD2 WILD-TYPE 95 149 115 88 55
'GTF2IRD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0967 (Fisher's exact test), Q value = 0.71

Table S1380.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GTF2IRD2 MUTATED 2 1 3 2 0
GTF2IRD2 WILD-TYPE 245 362 83 229 36
'GTF2IRD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.407 (Fisher's exact test), Q value = 0.98

Table S1381.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
GTF2IRD2 MUTATED 0 0 1 0 1 1
GTF2IRD2 WILD-TYPE 128 96 155 107 108 51
'GTF2IRD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.383 (Fisher's exact test), Q value = 0.98

Table S1382.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
GTF2IRD2 MUTATED 3 2 0
GTF2IRD2 WILD-TYPE 142 129 118
'GTF2IRD2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.977 (Fisher's exact test), Q value = 1

Table S1383.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
GTF2IRD2 MUTATED 1 1 1 0 2 0
GTF2IRD2 WILD-TYPE 58 47 89 53 111 31
'GTF2IRD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 0.98

Table S1384.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GTF2IRD2 MUTATED 3 2 3
GTF2IRD2 WILD-TYPE 502 277 187
'GTF2IRD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.78 (Fisher's exact test), Q value = 1

Table S1385.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GTF2IRD2 MUTATED 1 2 1 2 2 0
GTF2IRD2 WILD-TYPE 262 149 78 259 166 52
'GTF2IRD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S1386.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GTF2IRD2 MUTATED 2 3 1 1
GTF2IRD2 WILD-TYPE 270 174 232 275
'GTF2IRD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0417 (Fisher's exact test), Q value = 0.5

Table S1387.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GTF2IRD2 MUTATED 0 0 1 3 1 2
GTF2IRD2 WILD-TYPE 275 136 205 131 86 118

Figure S157.  Get High-res Image Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

'GTF2IRD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.128 (Fisher's exact test), Q value = 0.75

Table S1388.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
GTF2IRD2 MUTATED 0 1 0 2 0
GTF2IRD2 WILD-TYPE 178 119 66 90 112
'GTF2IRD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S1389.  Gene #129: 'GTF2IRD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
GTF2IRD2 MUTATED 2 0 1
GTF2IRD2 WILD-TYPE 277 181 107
'JAK1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.499 (Fisher's exact test), Q value = 1

Table S1390.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
JAK1 MUTATED 0 1 2 0 3 0 0 1
JAK1 WILD-TYPE 21 37 112 97 105 73 19 38
'JAK1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S1391.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
JAK1 MUTATED 2 4 1 0 0
JAK1 WILD-TYPE 94 148 115 89 56
'JAK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.673 (Fisher's exact test), Q value = 1

Table S1392.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
JAK1 MUTATED 2 4 1 2 1
JAK1 WILD-TYPE 245 359 85 229 35
'JAK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.414 (Fisher's exact test), Q value = 0.98

Table S1393.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
JAK1 MUTATED 1 2 2 0 0 1
JAK1 WILD-TYPE 127 94 154 107 109 51
'JAK1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1394.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
JAK1 MUTATED 2 2 1
JAK1 WILD-TYPE 143 129 117
'JAK1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S1395.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
JAK1 MUTATED 1 1 0 1 2 0
JAK1 WILD-TYPE 58 47 90 52 111 31
'JAK1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0412 (Fisher's exact test), Q value = 0.5

Table S1396.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
JAK1 MUTATED 7 0 4
JAK1 WILD-TYPE 498 279 186

Figure S158.  Get High-res Image Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'JAK1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.193 (Fisher's exact test), Q value = 0.85

Table S1397.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
JAK1 MUTATED 2 4 0 5 0 0
JAK1 WILD-TYPE 261 147 79 256 168 52
'JAK1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 0.88

Table S1398.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
JAK1 MUTATED 1 1 3 6
JAK1 WILD-TYPE 271 176 230 270
'JAK1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.123 (Fisher's exact test), Q value = 0.75

Table S1399.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
JAK1 MUTATED 5 0 1 4 1 0
JAK1 WILD-TYPE 270 136 205 130 86 120
'JAK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.87

Table S1400.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
JAK1 MUTATED 4 0 0 1 0
JAK1 WILD-TYPE 174 120 66 91 112
'JAK1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.17 (Fisher's exact test), Q value = 0.8

Table S1401.  Gene #130: 'JAK1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
JAK1 MUTATED 3 0 2
JAK1 WILD-TYPE 276 181 106
'FGFR3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0759 (Fisher's exact test), Q value = 0.65

Table S1402.  Gene #131: 'FGFR3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
FGFR3 MUTATED 1 0 0 1 0 0 0 1
FGFR3 WILD-TYPE 20 38 114 96 108 73 19 38
'FGFR3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S1403.  Gene #131: 'FGFR3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
FGFR3 MUTATED 0 1 1 1 0
FGFR3 WILD-TYPE 96 151 115 88 56
'FGFR3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1404.  Gene #131: 'FGFR3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
FGFR3 MUTATED 1 1 0 2 0
FGFR3 WILD-TYPE 246 362 86 229 36
'FGFR3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.415 (Fisher's exact test), Q value = 0.98

Table S1405.  Gene #131: 'FGFR3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
FGFR3 MUTATED 1 2 1
FGFR3 WILD-TYPE 504 277 189
'FGFR3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.396 (Fisher's exact test), Q value = 0.98

Table S1406.  Gene #131: 'FGFR3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
FGFR3 MUTATED 0 0 0 2 2 0
FGFR3 WILD-TYPE 263 151 79 259 166 52
'FGFR3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.566 (Fisher's exact test), Q value = 1

Table S1407.  Gene #131: 'FGFR3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
FGFR3 MUTATED 2 1 1 0
FGFR3 WILD-TYPE 270 176 232 276
'FGFR3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.25 (Fisher's exact test), Q value = 0.91

Table S1408.  Gene #131: 'FGFR3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
FGFR3 MUTATED 1 0 0 1 0 2
FGFR3 WILD-TYPE 274 136 206 133 87 118
'FBXW7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.817 (Fisher's exact test), Q value = 1

Table S1409.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
FBXW7 MUTATED 0 1 1 2 2 0 0 0
FBXW7 WILD-TYPE 21 37 113 95 106 73 19 39
'FBXW7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S1410.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
FBXW7 MUTATED 1 2 0 2 1
FBXW7 WILD-TYPE 95 150 116 87 55
'FBXW7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.156 (Fisher's exact test), Q value = 0.78

Table S1411.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
FBXW7 MUTATED 2 5 0 8 0
FBXW7 WILD-TYPE 245 358 86 223 36
'FBXW7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00408 (Fisher's exact test), Q value = 0.11

Table S1412.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
FBXW7 MUTATED 0 0 2 1 7 1
FBXW7 WILD-TYPE 128 96 154 106 102 51

Figure S159.  Get High-res Image Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

'FBXW7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1413.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
FBXW7 MUTATED 2 1 0
FBXW7 WILD-TYPE 143 130 118
'FBXW7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S1414.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
FBXW7 MUTATED 0 0 1 0 2 0
FBXW7 WILD-TYPE 59 48 89 53 111 31
'FBXW7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.23 (Fisher's exact test), Q value = 0.88

Table S1415.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
FBXW7 MUTATED 7 7 1
FBXW7 WILD-TYPE 498 272 189
'FBXW7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.147 (Fisher's exact test), Q value = 0.77

Table S1416.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
FBXW7 MUTATED 3 1 0 4 7 0
FBXW7 WILD-TYPE 260 150 79 257 161 52
'FBXW7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 0.96

Table S1417.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
FBXW7 MUTATED 7 3 3 2
FBXW7 WILD-TYPE 265 174 230 274
'FBXW7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0988 (Fisher's exact test), Q value = 0.72

Table S1418.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
FBXW7 MUTATED 3 1 3 2 0 6
FBXW7 WILD-TYPE 272 135 203 132 87 114
'FBXW7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0632 (Fisher's exact test), Q value = 0.6

Table S1419.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
FBXW7 MUTATED 1 5 0 0 2
FBXW7 WILD-TYPE 177 115 66 92 110
'FBXW7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.898 (Fisher's exact test), Q value = 1

Table S1420.  Gene #132: 'FBXW7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
FBXW7 MUTATED 5 2 1
FBXW7 WILD-TYPE 274 179 107
'SHANK2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.105 (Fisher's exact test), Q value = 0.75

Table S1421.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SHANK2 MUTATED 0 0 0 2 3 5 0 0
SHANK2 WILD-TYPE 21 38 114 95 105 68 19 39
'SHANK2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.85

Table S1422.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SHANK2 MUTATED 0 3 5 2 0
SHANK2 WILD-TYPE 96 149 111 87 56
'SHANK2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1423.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SHANK2 MUTATED 6 4 2 3 0
SHANK2 WILD-TYPE 241 359 84 228 36
'SHANK2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S1424.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
SHANK2 MUTATED 1 3 1 1 1 1
SHANK2 WILD-TYPE 127 93 155 106 108 51
'SHANK2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0532 (Fisher's exact test), Q value = 0.58

Table S1425.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
SHANK2 MUTATED 5 1 0
SHANK2 WILD-TYPE 140 130 118
'SHANK2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.343 (Fisher's exact test), Q value = 0.96

Table S1426.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
SHANK2 MUTATED 1 0 4 0 1 0
SHANK2 WILD-TYPE 58 48 86 53 112 31
'SHANK2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S1427.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SHANK2 MUTATED 10 4 1
SHANK2 WILD-TYPE 495 275 189
'SHANK2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.93

Table S1428.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SHANK2 MUTATED 2 5 0 6 2 0
SHANK2 WILD-TYPE 261 146 79 255 166 52
'SHANK2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 0.98

Table S1429.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SHANK2 MUTATED 4 3 6 2
SHANK2 WILD-TYPE 268 174 227 274
'SHANK2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 0.93

Table S1430.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SHANK2 MUTATED 5 0 6 2 0 2
SHANK2 WILD-TYPE 270 136 200 132 87 118
'SHANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0788 (Fisher's exact test), Q value = 0.66

Table S1431.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
SHANK2 MUTATED 2 1 0 0 5
SHANK2 WILD-TYPE 176 119 66 92 107
'SHANK2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.84

Table S1432.  Gene #133: 'SHANK2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
SHANK2 MUTATED 2 5 1
SHANK2 WILD-TYPE 277 176 107
'TRMT2A MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.953 (Fisher's exact test), Q value = 1

Table S1433.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
TRMT2A MUTATED 0 0 3 1 1 1 0 0
TRMT2A WILD-TYPE 21 38 111 96 107 72 19 39
'TRMT2A MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.92 (Fisher's exact test), Q value = 1

Table S1434.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
TRMT2A MUTATED 2 2 1 1 0
TRMT2A WILD-TYPE 94 150 115 88 56
'TRMT2A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.769 (Fisher's exact test), Q value = 1

Table S1435.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TRMT2A MUTATED 3 2 0 2 0
TRMT2A WILD-TYPE 244 361 86 229 36
'TRMT2A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S1436.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TRMT2A MUTATED 2 0 1 0 1 0
TRMT2A WILD-TYPE 126 96 155 107 108 52
'TRMT2A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 0.98

Table S1437.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
TRMT2A MUTATED 3 1 0
TRMT2A WILD-TYPE 142 130 118
'TRMT2A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1438.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
TRMT2A MUTATED 1 0 1 0 2 0
TRMT2A WILD-TYPE 58 48 89 53 111 31
'TRMT2A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S1439.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TRMT2A MUTATED 5 2 0
TRMT2A WILD-TYPE 500 277 190
'TRMT2A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S1440.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TRMT2A MUTATED 2 3 0 1 1 0
TRMT2A WILD-TYPE 261 148 79 260 167 52
'TRMT2A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S1441.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TRMT2A MUTATED 1 1 2 3
TRMT2A WILD-TYPE 271 176 231 273
'TRMT2A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1442.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TRMT2A MUTATED 4 1 1 0 0 1
TRMT2A WILD-TYPE 271 135 205 134 87 119
'TRMT2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S1443.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
TRMT2A MUTATED 3 1 0 0 0
TRMT2A WILD-TYPE 175 119 66 92 112
'TRMT2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 0.85

Table S1444.  Gene #134: 'TRMT2A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
TRMT2A MUTATED 4 0 0
TRMT2A WILD-TYPE 275 181 108
'CCNL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S1445.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CCNL2 MUTATED 0 0 1 1 1 0 0 1
CCNL2 WILD-TYPE 21 38 113 96 107 73 19 38
'CCNL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S1446.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CCNL2 MUTATED 1 2 0 1 0
CCNL2 WILD-TYPE 95 150 116 88 56
'CCNL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1447.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CCNL2 MUTATED 2 3 0 2 0
CCNL2 WILD-TYPE 245 360 86 229 36
'CCNL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.939 (Fisher's exact test), Q value = 1

Table S1448.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CCNL2 MUTATED 1 1 1 1 0 0
CCNL2 WILD-TYPE 127 95 155 106 109 52
'CCNL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S1449.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CCNL2 MUTATED 5 2 0
CCNL2 WILD-TYPE 500 277 190
'CCNL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.284 (Fisher's exact test), Q value = 0.93

Table S1450.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CCNL2 MUTATED 0 2 0 4 1 0
CCNL2 WILD-TYPE 263 149 79 257 167 52
'CCNL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S1451.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CCNL2 MUTATED 1 1 1 4
CCNL2 WILD-TYPE 271 176 232 272
'CCNL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.174 (Fisher's exact test), Q value = 0.82

Table S1452.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CCNL2 MUTATED 3 0 0 3 0 1
CCNL2 WILD-TYPE 272 136 206 131 87 119
'CCNL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.948 (Fisher's exact test), Q value = 1

Table S1453.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CCNL2 MUTATED 2 1 0 0 1
CCNL2 WILD-TYPE 176 119 66 92 111
'CCNL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1454.  Gene #135: 'CCNL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CCNL2 MUTATED 3 1 0
CCNL2 WILD-TYPE 276 180 108
'CLEC18B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.565 (Fisher's exact test), Q value = 1

Table S1455.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
CLEC18B MUTATED 0 1 1 1 0 0 0 0
CLEC18B WILD-TYPE 21 37 113 96 108 73 19 39
'CLEC18B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1456.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
CLEC18B MUTATED 1 1 1 0 0
CLEC18B WILD-TYPE 95 151 115 89 56
'CLEC18B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S1457.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CLEC18B MUTATED 2 1 1 2 0
CLEC18B WILD-TYPE 245 362 85 229 36
'CLEC18B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S1458.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
CLEC18B MUTATED 0 1 2 0 2 0
CLEC18B WILD-TYPE 128 95 154 107 107 52
'CLEC18B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.298 (Fisher's exact test), Q value = 0.93

Table S1459.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
CLEC18B MUTATED 1 0 2
CLEC18B WILD-TYPE 144 131 116
'CLEC18B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S1460.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
CLEC18B MUTATED 0 0 1 0 2 0
CLEC18B WILD-TYPE 59 48 89 53 111 31
'CLEC18B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S1461.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CLEC18B MUTATED 2 2 2
CLEC18B WILD-TYPE 503 277 188
'CLEC18B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.752 (Fisher's exact test), Q value = 1

Table S1462.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CLEC18B MUTATED 2 2 0 2 0 0
CLEC18B WILD-TYPE 261 149 79 259 168 52
'CLEC18B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S1463.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CLEC18B MUTATED 2 1 2 1
CLEC18B WILD-TYPE 270 176 231 275
'CLEC18B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 0.98

Table S1464.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CLEC18B MUTATED 1 1 1 1 2 0
CLEC18B WILD-TYPE 274 135 205 133 85 120
'CLEC18B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.857 (Fisher's exact test), Q value = 1

Table S1465.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
CLEC18B MUTATED 2 1 0 0 0
CLEC18B WILD-TYPE 176 119 66 92 112
'CLEC18B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 0.93

Table S1466.  Gene #136: 'CLEC18B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
CLEC18B MUTATED 3 0 0
CLEC18B WILD-TYPE 276 181 108
'RUFY1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 0.98

Table S1467.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
RUFY1 MUTATED 1 0 1 0 1 0 0 0
RUFY1 WILD-TYPE 20 38 113 97 107 73 19 39
'RUFY1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S1468.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
RUFY1 MUTATED 1 2 0 0 0
RUFY1 WILD-TYPE 95 150 116 89 56
'RUFY1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.93

Table S1469.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
RUFY1 MUTATED 1 2 1 1 1
RUFY1 WILD-TYPE 246 361 85 230 35
'RUFY1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.526 (Fisher's exact test), Q value = 1

Table S1470.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
RUFY1 MUTATED 2 1 0 0 1 0
RUFY1 WILD-TYPE 126 95 156 107 108 52
'RUFY1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S1471.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
RUFY1 MUTATED 4 2 0
RUFY1 WILD-TYPE 501 277 190
'RUFY1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.241 (Fisher's exact test), Q value = 0.91

Table S1472.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
RUFY1 MUTATED 0 3 0 2 1 0
RUFY1 WILD-TYPE 263 148 79 259 167 52
'RUFY1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S1473.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
RUFY1 MUTATED 1 1 1 3
RUFY1 WILD-TYPE 271 176 232 273
'RUFY1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.133 (Fisher's exact test), Q value = 0.76

Table S1474.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
RUFY1 MUTATED 5 0 0 0 0 1
RUFY1 WILD-TYPE 270 136 206 134 87 119
'RUFY1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S1475.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
RUFY1 MUTATED 2 1 0 1 0
RUFY1 WILD-TYPE 176 119 66 91 112
'RUFY1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.409 (Fisher's exact test), Q value = 0.98

Table S1476.  Gene #137: 'RUFY1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
RUFY1 MUTATED 3 0 1
RUFY1 WILD-TYPE 276 181 107
'GIPC3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.831 (Fisher's exact test), Q value = 1

Table S1477.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
GIPC3 MUTATED 0 0 2 0 1 0 0 0
GIPC3 WILD-TYPE 21 38 112 97 107 73 19 39
'GIPC3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.5 (Fisher's exact test), Q value = 1

Table S1478.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
GIPC3 MUTATED 1 1 0 0 1
GIPC3 WILD-TYPE 95 151 116 89 55
'GIPC3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.405 (Fisher's exact test), Q value = 0.98

Table S1479.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GIPC3 MUTATED 0 1 1 1 0
GIPC3 WILD-TYPE 247 362 85 230 36
'GIPC3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 0.98

Table S1480.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
GIPC3 MUTATED 0 2 1
GIPC3 WILD-TYPE 145 129 117
'GIPC3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0803 (Fisher's exact test), Q value = 0.67

Table S1481.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
GIPC3 MUTATED 2 1 0 0 0 0
GIPC3 WILD-TYPE 57 47 90 53 113 31
'GIPC3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.93

Table S1482.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GIPC3 MUTATED 4 0 0
GIPC3 WILD-TYPE 501 279 190
'GIPC3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S1483.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GIPC3 MUTATED 3 0 0 1 0 0
GIPC3 WILD-TYPE 260 151 79 260 168 52
'GIPC3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0779 (Fisher's exact test), Q value = 0.66

Table S1484.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GIPC3 MUTATED 1 0 3 0
GIPC3 WILD-TYPE 271 177 230 276
'GIPC3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S1485.  Gene #138: 'GIPC3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GIPC3 MUTATED 2 1 0 0 1 0
GIPC3 WILD-TYPE 273 135 206 134 86 120
'HPS3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.121 (Fisher's exact test), Q value = 0.75

Table S1486.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
HPS3 MUTATED 0 0 0 2 0 2 1 0
HPS3 WILD-TYPE 21 38 114 95 108 71 18 39
'HPS3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S1487.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
HPS3 MUTATED 0 1 2 2 0
HPS3 WILD-TYPE 96 151 114 87 56
'HPS3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.237 (Fisher's exact test), Q value = 0.9

Table S1488.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
HPS3 MUTATED 0 5 0 4 0
HPS3 WILD-TYPE 247 358 86 227 36
'HPS3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 0.94

Table S1489.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
HPS3 MUTATED 1 0 0 2 2 0
HPS3 WILD-TYPE 127 96 156 105 107 52
'HPS3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 0.75

Table S1490.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
HPS3 MUTATED 3 0 0
HPS3 WILD-TYPE 142 131 118
'HPS3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 0.78

Table S1491.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
HPS3 MUTATED 0 0 2 0 0 1
HPS3 WILD-TYPE 59 48 88 53 113 30
'HPS3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00514 (Fisher's exact test), Q value = 0.13

Table S1492.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
HPS3 MUTATED 1 7 1
HPS3 WILD-TYPE 504 272 189

Figure S160.  Get High-res Image Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

'HPS3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0042 (Fisher's exact test), Q value = 0.11

Table S1493.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
HPS3 MUTATED 0 0 0 2 5 2
HPS3 WILD-TYPE 263 151 79 259 163 50

Figure S161.  Get High-res Image Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

'HPS3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.131 (Fisher's exact test), Q value = 0.75

Table S1494.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
HPS3 MUTATED 6 1 1 1
HPS3 WILD-TYPE 266 176 232 275
'HPS3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.165 (Fisher's exact test), Q value = 0.79

Table S1495.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
HPS3 MUTATED 1 3 1 1 0 3
HPS3 WILD-TYPE 274 133 205 133 87 117
'HPS3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0601 (Fisher's exact test), Q value = 0.6

Table S1496.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
HPS3 MUTATED 0 4 0 1 1
HPS3 WILD-TYPE 178 116 66 91 111
'HPS3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S1497.  Gene #139: 'HPS3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
HPS3 MUTATED 3 1 2
HPS3 WILD-TYPE 276 180 106
'OR2T35 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1498.  Gene #140: 'OR2T35 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
OR2T35 MUTATED 0 0 1 1 1 0 0 0
OR2T35 WILD-TYPE 21 38 113 96 107 73 19 39
'OR2T35 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0951 (Fisher's exact test), Q value = 0.71

Table S1499.  Gene #140: 'OR2T35 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
OR2T35 MUTATED 0 0 2 0 1
OR2T35 WILD-TYPE 96 152 114 89 55
'OR2T35 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.894 (Fisher's exact test), Q value = 1

Table S1500.  Gene #140: 'OR2T35 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
OR2T35 MUTATED 2 1 0 1 0
OR2T35 WILD-TYPE 245 362 86 230 36
'OR2T35 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S1501.  Gene #140: 'OR2T35 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
OR2T35 MUTATED 3 1 0
OR2T35 WILD-TYPE 502 278 190
'OR2T35 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.717 (Fisher's exact test), Q value = 1

Table S1502.  Gene #140: 'OR2T35 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
OR2T35 MUTATED 2 1 0 0 1 0
OR2T35 WILD-TYPE 261 150 79 261 167 52
'OR2T35 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.259 (Fisher's exact test), Q value = 0.92

Table S1503.  Gene #140: 'OR2T35 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
OR2T35 MUTATED 1 0 0 3
OR2T35 WILD-TYPE 271 177 233 273
'OR2T35 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S1504.  Gene #140: 'OR2T35 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
OR2T35 MUTATED 3 1 0 0 0 0
OR2T35 WILD-TYPE 272 135 206 134 87 120
'PPIL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 0.98

Table S1505.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
PPIL2 MUTATED 1 1 1 3 0
PPIL2 WILD-TYPE 246 362 85 228 36
'PPIL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S1506.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
PPIL2 MUTATED 1 1 1 0 2 0
PPIL2 WILD-TYPE 127 95 155 107 107 52
'PPIL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1507.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
PPIL2 MUTATED 3 2 1
PPIL2 WILD-TYPE 502 277 189
'PPIL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.409 (Fisher's exact test), Q value = 0.98

Table S1508.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
PPIL2 MUTATED 2 1 1 0 2 0
PPIL2 WILD-TYPE 261 150 78 261 166 52
'PPIL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 0.98

Table S1509.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
PPIL2 MUTATED 1 0 3 1
PPIL2 WILD-TYPE 271 177 230 275
'PPIL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1510.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
PPIL2 MUTATED 2 1 1 1 0 0
PPIL2 WILD-TYPE 273 135 205 133 87 120
'PPIL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S1511.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
PPIL2 MUTATED 0 0 1 1 1
PPIL2 WILD-TYPE 178 120 65 91 111
'PPIL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0395 (Fisher's exact test), Q value = 0.5

Table S1512.  Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
PPIL2 MUTATED 0 3 0
PPIL2 WILD-TYPE 279 178 108

Figure S162.  Get High-res Image Gene #141: 'PPIL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NPAS4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S1513.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
NPAS4 MUTATED 0 0 4 1 1 0 0 0
NPAS4 WILD-TYPE 21 38 110 96 107 73 19 39
'NPAS4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.148 (Fisher's exact test), Q value = 0.77

Table S1514.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
NPAS4 MUTATED 3 0 1 1 1
NPAS4 WILD-TYPE 93 152 115 88 55
'NPAS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 0.87

Table S1515.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
NPAS4 MUTATED 5 1 0 3 0
NPAS4 WILD-TYPE 242 362 86 228 36
'NPAS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 0.97

Table S1516.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
NPAS4 MUTATED 3 0 1 0 2 0
NPAS4 WILD-TYPE 125 96 155 107 107 52
'NPAS4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1517.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
NPAS4 MUTATED 1 2 1
NPAS4 WILD-TYPE 144 129 117
'NPAS4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.875 (Fisher's exact test), Q value = 1

Table S1518.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
NPAS4 MUTATED 0 1 1 0 2 0
NPAS4 WILD-TYPE 59 47 89 53 111 31
'NPAS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.327 (Fisher's exact test), Q value = 0.94

Table S1519.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
NPAS4 MUTATED 6 3 0
NPAS4 WILD-TYPE 499 276 190
'NPAS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 0.88

Table S1520.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
NPAS4 MUTATED 4 2 0 0 3 0
NPAS4 WILD-TYPE 259 149 79 261 165 52
'NPAS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.385 (Fisher's exact test), Q value = 0.98

Table S1521.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
NPAS4 MUTATED 4 0 3 2
NPAS4 WILD-TYPE 268 177 230 274
'NPAS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 0.77

Table S1522.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
NPAS4 MUTATED 2 1 1 0 3 2
NPAS4 WILD-TYPE 273 135 205 134 84 118
'NPAS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 0.91

Table S1523.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
NPAS4 MUTATED 0 2 1 0 1
NPAS4 WILD-TYPE 178 118 65 92 111
'NPAS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1524.  Gene #142: 'NPAS4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
NPAS4 MUTATED 3 1 0
NPAS4 WILD-TYPE 276 180 108
'SHISA4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0873 (Fisher's exact test), Q value = 0.68

Table S1525.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
SHISA4 MUTATED 0 2 1 0 0 0 0 0
SHISA4 WILD-TYPE 21 36 113 97 108 73 19 39
'SHISA4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S1526.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
SHISA4 MUTATED 1 2 0 0 0
SHISA4 WILD-TYPE 95 150 116 89 56
'SHISA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0777 (Fisher's exact test), Q value = 0.66

Table S1527.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
SHISA4 MUTATED 2 0 0 2 1
SHISA4 WILD-TYPE 245 363 86 229 35
'SHISA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.75

Table S1528.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
SHISA4 MUTATED 0 0 0 1 2 1
SHISA4 WILD-TYPE 128 96 156 106 107 51
'SHISA4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.497 (Fisher's exact test), Q value = 1

Table S1529.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
SHISA4 MUTATED 2 1 2
SHISA4 WILD-TYPE 503 278 188
'SHISA4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 0.93

Table S1530.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
SHISA4 MUTATED 1 0 1 2 0 1
SHISA4 WILD-TYPE 262 151 78 259 168 51
'SHISA4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S1531.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
SHISA4 MUTATED 1 1 2 1
SHISA4 WILD-TYPE 271 176 231 275
'SHISA4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1532.  Gene #143: 'SHISA4 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
SHISA4 MUTATED 2 1 1 1 0 0
SHISA4 WILD-TYPE 273 135 205 133 87 120
'MLL MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S1533.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
MLL MUTATED 0 2 2 1 1 2 0 1
MLL WILD-TYPE 21 36 112 96 107 71 19 38
'MLL MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S1534.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
MLL MUTATED 1 5 2 1 0
MLL WILD-TYPE 95 147 114 88 56
'MLL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0596 (Fisher's exact test), Q value = 0.6

Table S1535.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
MLL MUTATED 5 3 0 7 2
MLL WILD-TYPE 242 360 86 224 34
'MLL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0858 (Fisher's exact test), Q value = 0.68

Table S1536.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
MLL MUTATED 3 2 0 1 5 1
MLL WILD-TYPE 125 94 156 106 104 51
'MLL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.688 (Fisher's exact test), Q value = 1

Table S1537.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
MLL MUTATED 3 1 2
MLL WILD-TYPE 142 130 116
'MLL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.272 (Fisher's exact test), Q value = 0.93

Table S1538.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
MLL MUTATED 1 1 1 0 1 2
MLL WILD-TYPE 58 47 89 53 112 29
'MLL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.25 (Fisher's exact test), Q value = 0.91

Table S1539.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
MLL MUTATED 7 8 2
MLL WILD-TYPE 498 271 188
'MLL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.356 (Fisher's exact test), Q value = 0.96

Table S1540.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
MLL MUTATED 4 1 0 5 5 2
MLL WILD-TYPE 259 150 79 256 163 50
'MLL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.83 (Fisher's exact test), Q value = 1

Table S1541.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
MLL MUTATED 5 2 3 6
MLL WILD-TYPE 267 175 230 270
'MLL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.85

Table S1542.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
MLL MUTATED 6 3 0 2 2 3
MLL WILD-TYPE 269 133 206 132 85 117
'MLL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 0.93

Table S1543.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
MLL MUTATED 2 4 1 1 0
MLL WILD-TYPE 176 116 65 91 112
'MLL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0691 (Fisher's exact test), Q value = 0.62

Table S1544.  Gene #144: 'MLL MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
MLL MUTATED 7 0 1
MLL WILD-TYPE 272 181 107
'ACVR1B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.89 (Fisher's exact test), Q value = 1

Table S1545.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ACVR1B MUTATED 0 0 1 2 2 0 0 0
ACVR1B WILD-TYPE 21 38 113 95 106 73 19 39
'ACVR1B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1546.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ACVR1B MUTATED 1 2 1 1 0
ACVR1B WILD-TYPE 95 150 115 88 56
'ACVR1B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.949 (Fisher's exact test), Q value = 1

Table S1547.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ACVR1B MUTATED 2 2 0 2 0
ACVR1B WILD-TYPE 245 361 86 229 36
'ACVR1B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1548.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ACVR1B MUTATED 2 0 1 0 1 0
ACVR1B WILD-TYPE 126 96 155 107 108 52
'ACVR1B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S1549.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ACVR1B MUTATED 2 2 0
ACVR1B WILD-TYPE 143 129 118
'ACVR1B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.201 (Fisher's exact test), Q value = 0.86

Table S1550.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ACVR1B MUTATED 2 0 2 0 0 0
ACVR1B WILD-TYPE 57 48 88 53 113 31
'ACVR1B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S1551.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ACVR1B MUTATED 3 4 0
ACVR1B WILD-TYPE 502 275 190
'ACVR1B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.478 (Fisher's exact test), Q value = 1

Table S1552.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ACVR1B MUTATED 1 2 0 1 3 0
ACVR1B WILD-TYPE 262 149 79 260 165 52
'ACVR1B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.373 (Fisher's exact test), Q value = 0.98

Table S1553.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ACVR1B MUTATED 3 0 3 1
ACVR1B WILD-TYPE 269 177 230 275
'ACVR1B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S1554.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ACVR1B MUTATED 2 2 0 1 1 1
ACVR1B WILD-TYPE 273 134 206 133 86 119
'ACVR1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S1555.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ACVR1B MUTATED 1 2 0 0 0
ACVR1B WILD-TYPE 177 118 66 92 112
'ACVR1B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.303 (Fisher's exact test), Q value = 0.93

Table S1556.  Gene #145: 'ACVR1B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ACVR1B MUTATED 3 0 0
ACVR1B WILD-TYPE 276 181 108
'GPR158 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1557.  Gene #146: 'GPR158 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
GPR158 MUTATED 1 1 0 1 0
GPR158 WILD-TYPE 246 362 86 230 36
'GPR158 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S1558.  Gene #146: 'GPR158 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
GPR158 MUTATED 1 2 0
GPR158 WILD-TYPE 504 277 190
'GPR158 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S1559.  Gene #146: 'GPR158 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
GPR158 MUTATED 0 0 0 1 2 0
GPR158 WILD-TYPE 263 151 79 260 166 52
'GPR158 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.325 (Fisher's exact test), Q value = 0.94

Table S1560.  Gene #146: 'GPR158 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
GPR158 MUTATED 1 0 2 0
GPR158 WILD-TYPE 271 177 231 276
'GPR158 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.306 (Fisher's exact test), Q value = 0.93

Table S1561.  Gene #146: 'GPR158 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
GPR158 MUTATED 0 0 2 0 0 1
GPR158 WILD-TYPE 275 136 204 134 87 119
'ARHGEF15 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S1562.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ARHGEF15 MUTATED 1 0 4 2 1 0 0 0
ARHGEF15 WILD-TYPE 20 38 110 95 107 73 19 39
'ARHGEF15 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.199 (Fisher's exact test), Q value = 0.86

Table S1563.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ARHGEF15 MUTATED 4 1 1 2 0
ARHGEF15 WILD-TYPE 92 151 115 87 56
'ARHGEF15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 0.96

Table S1564.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ARHGEF15 MUTATED 4 2 0 2 1
ARHGEF15 WILD-TYPE 243 361 86 229 35
'ARHGEF15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1565.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ARHGEF15 MUTATED 1 0 1 1 1 0
ARHGEF15 WILD-TYPE 127 96 155 106 108 52
'ARHGEF15 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S1566.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #5: 'RPPA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 145 131 118
ARHGEF15 MUTATED 2 3 2
ARHGEF15 WILD-TYPE 143 128 116
'ARHGEF15 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S1567.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 59 48 90 53 113 31
ARHGEF15 MUTATED 2 0 2 0 3 0
ARHGEF15 WILD-TYPE 57 48 88 53 110 31
'ARHGEF15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 0.94

Table S1568.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ARHGEF15 MUTATED 6 3 0
ARHGEF15 WILD-TYPE 499 276 190
'ARHGEF15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S1569.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ARHGEF15 MUTATED 3 3 0 1 2 0
ARHGEF15 WILD-TYPE 260 148 79 260 166 52
'ARHGEF15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S1570.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ARHGEF15 MUTATED 3 1 1 3
ARHGEF15 WILD-TYPE 269 176 232 273
'ARHGEF15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.564 (Fisher's exact test), Q value = 1

Table S1571.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ARHGEF15 MUTATED 3 2 0 1 1 1
ARHGEF15 WILD-TYPE 272 134 206 133 86 119
'ARHGEF15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.856 (Fisher's exact test), Q value = 1

Table S1572.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ARHGEF15 MUTATED 2 1 0 0 0
ARHGEF15 WILD-TYPE 176 119 66 92 112
'ARHGEF15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.3 (Fisher's exact test), Q value = 0.93

Table S1573.  Gene #147: 'ARHGEF15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ARHGEF15 MUTATED 3 0 0
ARHGEF15 WILD-TYPE 276 181 108
'ZNF397 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0714 (Fisher's exact test), Q value = 0.63

Table S1574.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6 CLUS_7 CLUS_8
ALL 21 38 114 97 108 73 19 39
ZNF397 MUTATED 0 1 0 0 1 0 1 0
ZNF397 WILD-TYPE 21 37 114 97 107 73 18 39
'ZNF397 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S1575.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 96 152 116 89 56
ZNF397 MUTATED 0 2 1 0 0
ZNF397 WILD-TYPE 96 150 115 89 56
'ZNF397 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.8

Table S1576.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
ZNF397 MUTATED 5 1 0 1 0
ZNF397 WILD-TYPE 242 362 86 230 36
'ZNF397 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S1577.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
ZNF397 MUTATED 2 2 1 1 0 0
ZNF397 WILD-TYPE 126 94 155 106 109 52
'ZNF397 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1578.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
ZNF397 MUTATED 4 2 1
ZNF397 WILD-TYPE 501 277 189
'ZNF397 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1579.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
ZNF397 MUTATED 2 1 0 4 0 0
ZNF397 WILD-TYPE 261 150 79 257 168 52
'ZNF397 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.723 (Fisher's exact test), Q value = 1

Table S1580.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
ZNF397 MUTATED 1 1 3 2
ZNF397 WILD-TYPE 271 176 230 274
'ZNF397 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S1581.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
ZNF397 MUTATED 3 0 2 2 0 0
ZNF397 WILD-TYPE 272 136 204 132 87 120
'ZNF397 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.608 (Fisher's exact test), Q value = 1

Table S1582.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 178 120 66 92 112
ZNF397 MUTATED 2 0 1 0 1
ZNF397 WILD-TYPE 176 120 65 92 111
'ZNF397 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S1583.  Gene #148: 'ZNF397 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 279 181 108
ZNF397 MUTATED 2 2 0
ZNF397 WILD-TYPE 277 179 108
'COL9A2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.309 (Fisher's exact test), Q value = 0.93

Table S1584.  Gene #149: 'COL9A2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
COL9A2 MUTATED 1 0 0 2 0
COL9A2 WILD-TYPE 246 363 86 229 36
'COL9A2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.76

Table S1585.  Gene #149: 'COL9A2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
COL9A2 MUTATED 0 1 0 0 2 0
COL9A2 WILD-TYPE 128 95 156 107 107 52
'COL9A2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.93

Table S1586.  Gene #149: 'COL9A2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
COL9A2 MUTATED 1 2 0
COL9A2 WILD-TYPE 504 277 190
'COL9A2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S1587.  Gene #149: 'COL9A2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
COL9A2 MUTATED 1 0 0 0 2 0
COL9A2 WILD-TYPE 262 151 79 261 166 52
'TXNDC2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S1588.  Gene #150: 'TXNDC2 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
TXNDC2 MUTATED 0 2 1 1 0
TXNDC2 WILD-TYPE 247 361 85 230 36
'TXNDC2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.69 (Fisher's exact test), Q value = 1

Table S1589.  Gene #150: 'TXNDC2 MUTATION STATUS' versus Molecular Subtype #4: 'METHLYATION_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 128 96 156 107 109 52
TXNDC2 MUTATED 1 0 1 0 2 0
TXNDC2 WILD-TYPE 127 96 155 107 107 52
'TXNDC2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.75

Table S1590.  Gene #150: 'TXNDC2 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
TXNDC2 MUTATED 1 3 0
TXNDC2 WILD-TYPE 504 276 190
'TXNDC2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.93

Table S1591.  Gene #150: 'TXNDC2 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
TXNDC2 MUTATED 1 1 0 0 1 1
TXNDC2 WILD-TYPE 262 150 79 261 167 51
'TXNDC2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 0.88

Table S1592.  Gene #150: 'TXNDC2 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
TXNDC2 MUTATED 3 0 0 1
TXNDC2 WILD-TYPE 269 177 233 275
'TXNDC2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1593.  Gene #150: 'TXNDC2 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
TXNDC2 MUTATED 2 1 0 0 0 1
TXNDC2 WILD-TYPE 273 135 206 134 87 119
'CD244 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.355 (Fisher's exact test), Q value = 0.96

Table S1594.  Gene #151: 'CD244 MUTATION STATUS' versus Molecular Subtype #3: 'CN_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5
ALL 247 363 86 231 36
CD244 MUTATED 2 0 0 1 0
CD244 WILD-TYPE 245 363 86 230 36
'CD244 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.75

Table S1595.  Gene #151: 'CD244 MUTATION STATUS' versus Molecular Subtype #7: 'MRNASEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3
ALL 505 279 190
CD244 MUTATED 0 2 1
CD244 WILD-TYPE 505 277 189
'CD244 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.28 (Fisher's exact test), Q value = 0.93

Table S1596.  Gene #151: 'CD244 MUTATION STATUS' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 263 151 79 261 168 52
CD244 MUTATED 0 2 0 1 0 0
CD244 WILD-TYPE 263 149 79 260 168 52
'CD244 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1597.  Gene #151: 'CD244 MUTATION STATUS' versus Molecular Subtype #9: 'MIRSEQ_CNMF'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4
ALL 272 177 233 276
CD244 MUTATED 1 0 1 1
CD244 WILD-TYPE 271 177 232 275
'CD244 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1598.  Gene #151: 'CD244 MUTATION STATUS' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'

nPatients CLUS_1 CLUS_2 CLUS_3 CLUS_4 CLUS_5 CLUS_6
ALL 275 136 206 134 87 120
CD244 MUTATED 2 0 1 0 0 0
CD244 WILD-TYPE 273 136 205 134 87 120
Methods & Data
Input

  • Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline

  • Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/BRCA-TP/15165591/transformed.cor.cli.txt

  • Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/BRCA-TP/15246568/BRCA-TP.transferedmergedcluster.txt

  • Number of patients = 977

  • Number of significantly mutated genes = 151

  • Number of Molecular subtypes = 12

  • Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References
[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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