This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 82 arm-level events and 12 molecular subtypes across 516 patients, 440 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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2p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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4q gain cnv correlated to 'MRNASEQ_CNMF'.
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5p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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6p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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7p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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8q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9q gain cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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10p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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13q gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', and 'MRNASEQ_CHIERARCHICAL'.
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14q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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15q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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16p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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16q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', and 'MIRSEQ_CNMF'.
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17p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CNMF'.
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17q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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22q gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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xp gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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xq gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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1p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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1q loss cnv correlated to 'RPPA_CNMF'.
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3p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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4p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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6q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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7p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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7q loss cnv correlated to 'CN_CNMF'.
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8p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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9p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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9q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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11q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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12p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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12q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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13q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
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18p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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18q loss cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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19p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', and 'MRNASEQ_CHIERARCHICAL'.
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xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 440 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 7p gain | 259 (50%) | 257 |
0.742 (0.841) |
0.74 (0.84) |
1e-05 (0.000101) |
0.0155 (0.0445) |
0.00097 (0.0044) |
0.014 (0.041) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
5e-05 (0.00037) |
5e-05 (0.00037) |
1e-05 (0.000101) |
| 8q gain | 244 (47%) | 272 |
0.0349 (0.0842) |
0.0199 (0.0548) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.65 (0.76) |
0.793 (0.879) |
4e-05 (0.00031) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.00158 (0.00673) |
0.00811 (0.0267) |
1e-05 (0.000101) |
| 8p loss | 203 (39%) | 313 |
0.0132 (0.0395) |
0.0938 (0.185) |
1e-05 (0.000101) |
0.0477 (0.108) |
0.076 (0.156) |
0.0055 (0.0191) |
1e-05 (0.000101) |
7e-05 (0.000489) |
0.0104 (0.0327) |
0.041 (0.0965) |
0.0219 (0.059) |
0.0119 (0.0363) |
| 10q loss | 136 (26%) | 380 |
0.183 (0.304) |
0.0531 (0.117) |
0.00076 (0.00358) |
0.0307 (0.077) |
0.0296 (0.0752) |
0.0243 (0.0636) |
9e-05 (0.000598) |
1e-05 (0.000101) |
0.00557 (0.0193) |
0.0116 (0.0355) |
0.0217 (0.0586) |
0.0024 (0.00948) |
| 2q gain | 141 (27%) | 375 |
0.018 (0.0507) |
0.0442 (0.102) |
1e-05 (0.000101) |
0.0003 (0.00156) |
0.977 (1.00) |
0.707 (0.81) |
0.0386 (0.0918) |
0.0191 (0.0533) |
0.00257 (0.01) |
0.103 (0.199) |
0.0344 (0.0839) |
0.0107 (0.0332) |
| 11q gain | 114 (22%) | 402 |
0.00066 (0.00318) |
0.00092 (0.00423) |
1e-05 (0.000101) |
0.0439 (0.101) |
0.0209 (0.0568) |
0.928 (0.974) |
0.145 (0.262) |
0.00025 (0.00137) |
0.00035 (0.00178) |
1e-05 (0.000101) |
0.398 (0.547) |
0.00507 (0.0179) |
| 12p gain | 137 (27%) | 379 |
0.196 (0.32) |
0.0193 (0.0537) |
1e-05 (0.000101) |
0.00027 (0.00144) |
0.0236 (0.0625) |
0.358 (0.499) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.405 (0.55) |
1e-05 (0.000101) |
| 18q gain | 70 (14%) | 446 |
0.452 (0.588) |
0.484 (0.619) |
2e-05 (0.000184) |
1e-05 (0.000101) |
0.0237 (0.0625) |
0.18 (0.3) |
0.00067 (0.0032) |
4e-05 (0.00031) |
0.00668 (0.0225) |
0.00188 (0.00771) |
0.0443 (0.102) |
0.00283 (0.0108) |
| 20q gain | 192 (37%) | 324 |
0.00383 (0.014) |
0.00918 (0.0297) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.101 (0.196) |
0.0933 (0.184) |
1e-05 (0.000101) |
1e-05 (0.000101) |
2e-05 (0.000184) |
3e-05 (0.000248) |
0.0609 (0.13) |
1e-05 (0.000101) |
| 4q loss | 141 (27%) | 375 |
0.00096 (0.00437) |
0.00925 (0.0298) |
8e-05 (0.000547) |
1e-05 (0.000101) |
0.179 (0.3) |
0.321 (0.463) |
3e-05 (0.000248) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.0836 (0.169) |
0.00016 (0.000948) |
| 13q loss | 258 (50%) | 258 |
0.0583 (0.125) |
0.452 (0.588) |
1e-05 (0.000101) |
0.0423 (0.099) |
0.00534 (0.0187) |
0.0136 (0.0402) |
0.00043 (0.00217) |
1e-05 (0.000101) |
0.00698 (0.0234) |
0.0224 (0.0598) |
0.273 (0.412) |
0.00426 (0.0154) |
| 15q loss | 241 (47%) | 275 |
0.323 (0.463) |
0.431 (0.573) |
1e-05 (0.000101) |
0.00246 (0.00968) |
0.0403 (0.0953) |
0.00864 (0.0282) |
0.00518 (0.0183) |
1e-05 (0.000101) |
7e-05 (0.000489) |
0.0119 (0.0363) |
0.577 (0.696) |
3e-05 (0.000248) |
| 21q loss | 167 (32%) | 349 |
0.184 (0.304) |
0.144 (0.262) |
1e-05 (0.000101) |
0.00173 (0.00718) |
0.015 (0.0433) |
0.0466 (0.106) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
6e-05 (0.000431) |
0.537 (0.665) |
0.00033 (0.00171) |
| 1q gain | 310 (60%) | 206 |
0.336 (0.477) |
0.72 (0.822) |
0.00392 (0.0143) |
0.00131 (0.00578) |
0.00326 (0.0122) |
0.0261 (0.0677) |
0.00268 (0.0104) |
0.0271 (0.0696) |
0.316 (0.458) |
0.0283 (0.0725) |
0.0314 (0.078) |
0.219 (0.346) |
| 11p gain | 94 (18%) | 422 |
0.00964 (0.0308) |
0.0096 (0.0308) |
9e-05 (0.000598) |
0.106 (0.203) |
0.0155 (0.0445) |
0.713 (0.815) |
0.451 (0.588) |
0.00034 (0.00173) |
0.00145 (0.00626) |
1e-05 (0.000101) |
0.22 (0.346) |
0.0155 (0.0445) |
| 12q gain | 130 (25%) | 386 |
0.195 (0.318) |
0.02 (0.0548) |
1e-05 (0.000101) |
3e-05 (0.000248) |
0.0793 (0.162) |
0.216 (0.345) |
1e-05 (0.000101) |
1e-05 (0.000101) |
2e-05 (0.000184) |
1e-05 (0.000101) |
0.222 (0.348) |
1e-05 (0.000101) |
| 20p gain | 173 (34%) | 343 |
0.0704 (0.147) |
0.138 (0.252) |
5e-05 (0.00037) |
0.00018 (0.00104) |
0.17 (0.291) |
0.501 (0.633) |
0.00067 (0.0032) |
1e-05 (0.000101) |
9e-05 (0.000598) |
0.00018 (0.00104) |
0.0465 (0.106) |
0.00018 (0.00104) |
| 5q loss | 153 (30%) | 363 |
0.2 (0.325) |
0.205 (0.331) |
1e-05 (0.000101) |
3e-05 (0.000248) |
0.0194 (0.0537) |
0.0762 (0.156) |
4e-05 (0.00031) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.661 (0.767) |
1e-05 (0.000101) |
| 16p loss | 118 (23%) | 398 |
0.285 (0.424) |
1 (1.00) |
0.0008 (0.00373) |
0.00151 (0.00646) |
0.574 (0.695) |
0.0136 (0.0402) |
1e-05 (0.000101) |
0.00026 (0.0014) |
0.0133 (0.0395) |
0.0239 (0.0627) |
0.606 (0.72) |
0.00901 (0.0294) |
| 19p loss | 248 (48%) | 268 |
0.603 (0.719) |
0.902 (0.957) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.876 (0.941) |
0.391 (0.539) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.035 (0.0842) |
0.00299 (0.0113) |
| 2p gain | 153 (30%) | 363 |
0.19 (0.311) |
0.159 (0.278) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.574 (0.695) |
0.862 (0.934) |
0.00202 (0.00818) |
0.00029 (0.00153) |
3e-05 (0.000248) |
0.00137 (0.00602) |
0.0537 (0.118) |
0.00015 (0.000917) |
| 3q gain | 89 (17%) | 427 |
6e-05 (0.000431) |
0.00034 (0.00173) |
0.489 (0.625) |
0.111 (0.21) |
2e-05 (0.000184) |
1e-05 (0.000101) |
0.00742 (0.0247) |
0.0287 (0.0734) |
0.235 (0.362) |
0.0016 (0.00676) |
||
| 6p gain | 143 (28%) | 373 |
0.155 (0.273) |
0.0332 (0.0813) |
0.00277 (0.0106) |
7e-05 (0.000489) |
0.00676 (0.0227) |
0.863 (0.934) |
0.0989 (0.192) |
0.0182 (0.0511) |
0.0723 (0.15) |
0.00527 (0.0185) |
0.579 (0.696) |
0.0137 (0.0402) |
| 10p gain | 111 (22%) | 405 |
0.119 (0.222) |
0.0871 (0.175) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.0542 (0.118) |
0.197 (0.32) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.0002 (0.00114) |
0.00013 (0.000805) |
0.323 (0.463) |
0.00081 (0.00376) |
| 17q gain | 191 (37%) | 325 |
0.534 (0.662) |
1 (1.00) |
1e-05 (0.000101) |
3e-05 (0.000248) |
0.45 (0.588) |
0.184 (0.304) |
0.00206 (0.00831) |
1e-05 (0.000101) |
0.0001 (0.000656) |
8e-05 (0.000547) |
0.481 (0.616) |
0.00046 (0.0023) |
| 3p loss | 213 (41%) | 303 |
0.342 (0.482) |
0.113 (0.213) |
0.0001 (0.000656) |
2e-05 (0.000184) |
0.653 (0.762) |
0.458 (0.595) |
0.00449 (0.0161) |
3e-05 (0.000248) |
0.0173 (0.0488) |
0.0159 (0.0454) |
0.223 (0.348) |
0.0308 (0.077) |
| 4p loss | 124 (24%) | 392 |
0.186 (0.306) |
0.379 (0.524) |
0.00115 (0.0051) |
0.00027 (0.00144) |
0.524 (0.656) |
0.579 (0.696) |
0.0264 (0.0683) |
1e-05 (0.000101) |
1e-05 (0.000101) |
3e-05 (0.000248) |
0.157 (0.276) |
9e-05 (0.000598) |
| 9q loss | 254 (49%) | 262 |
0.851 (0.926) |
1 (1.00) |
1e-05 (0.000101) |
0.00224 (0.00896) |
0.291 (0.431) |
0.0307 (0.077) |
0.0553 (0.12) |
0.00066 (0.00318) |
0.00191 (0.0078) |
5e-05 (0.00037) |
0.309 (0.449) |
0.0126 (0.038) |
| 16q loss | 145 (28%) | 371 |
0.576 (0.695) |
0.643 (0.754) |
0.0003 (0.00156) |
0.00026 (0.0014) |
0.226 (0.351) |
0.151 (0.269) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.0236 (0.0625) |
0.0141 (0.0412) |
0.827 (0.908) |
0.00275 (0.0106) |
| 17p loss | 216 (42%) | 300 |
0.631 (0.745) |
0.317 (0.458) |
1e-05 (0.000101) |
3e-05 (0.000248) |
0.0411 (0.0966) |
0.0124 (0.0373) |
4e-05 (0.00031) |
0.00017 (0.001) |
0.425 (0.566) |
0.185 (0.305) |
0.831 (0.91) |
0.0145 (0.0423) |
| 19q loss | 160 (31%) | 356 |
0.345 (0.486) |
0.463 (0.6) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.215 (0.343) |
0.473 (0.609) |
0.00011 (0.000707) |
4e-05 (0.00031) |
0.0002 (0.00114) |
1e-05 (0.000101) |
0.217 (0.346) |
0.0347 (0.0842) |
| 20p loss | 113 (22%) | 403 |
0.405 (0.55) |
0.223 (0.348) |
0.00188 (0.00771) |
0.00959 (0.0308) |
0.00184 (0.00761) |
0.0171 (0.0484) |
0.00021 (0.00117) |
0.00148 (0.00636) |
1 (1.00) |
0.996 (1.00) |
0.374 (0.518) |
0.0306 (0.077) |
| 22q loss | 217 (42%) | 299 |
0.33 (0.471) |
0.661 (0.767) |
1e-05 (0.000101) |
1e-05 (0.000101) |
1 (1.00) |
0.421 (0.563) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.00016 (0.000948) |
2e-05 (0.000184) |
0.105 (0.202) |
0.00013 (0.000805) |
| 1p gain | 150 (29%) | 366 |
0.91 (0.963) |
0.826 (0.908) |
1e-05 (0.000101) |
0.538 (0.665) |
0.0236 (0.0625) |
0.0181 (0.051) |
0.033 (0.0813) |
0.0107 (0.0333) |
0.0362 (0.0869) |
0.168 (0.289) |
0.397 (0.547) |
0.154 (0.272) |
| 5p gain | 270 (52%) | 246 |
0.267 (0.405) |
0.41 (0.554) |
1e-05 (0.000101) |
0.00814 (0.0267) |
0.258 (0.393) |
0.0529 (0.117) |
0.422 (0.563) |
0.00738 (0.0246) |
0.0332 (0.0813) |
0.0432 (0.1) |
0.591 (0.708) |
4e-05 (0.00031) |
| 7q gain | 212 (41%) | 304 |
1 (1.00) |
0.806 (0.89) |
1e-05 (0.000101) |
0.111 (0.209) |
0.0553 (0.12) |
0.08 (0.163) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.00503 (0.0179) |
0.00073 (0.00345) |
0.0916 (0.181) |
2e-05 (0.000184) |
| 14q gain | 130 (25%) | 386 |
0.109 (0.208) |
0.265 (0.403) |
1e-05 (0.000101) |
0.0123 (0.0372) |
0.247 (0.378) |
0.174 (0.296) |
0.0488 (0.11) |
1e-05 (0.000101) |
0.00013 (0.000805) |
0.00063 (0.00307) |
0.184 (0.304) |
0.115 (0.215) |
| 18p gain | 91 (18%) | 425 |
0.914 (0.963) |
1 (1.00) |
1e-05 (0.000101) |
3e-05 (0.000248) |
0.104 (0.2) |
0.881 (0.945) |
0.116 (0.216) |
0.00078 (0.00365) |
0.00974 (0.031) |
0.00642 (0.0219) |
0.152 (0.269) |
7e-05 (0.000489) |
| 9p loss | 270 (52%) | 246 |
0.538 (0.665) |
0.897 (0.956) |
1e-05 (0.000101) |
0.00196 (0.00797) |
0.478 (0.614) |
0.0257 (0.0668) |
0.057 (0.123) |
0.00013 (0.000805) |
0.00632 (0.0216) |
0.00164 (0.0069) |
0.148 (0.266) |
0.092 (0.182) |
| 10p loss | 114 (22%) | 402 |
0.184 (0.304) |
0.0531 (0.117) |
0.00049 (0.00244) |
0.256 (0.391) |
0.0618 (0.131) |
0.0128 (0.0383) |
0.00098 (0.00442) |
1e-05 (0.000101) |
0.00346 (0.0128) |
0.308 (0.448) |
0.0386 (0.0918) |
0.0631 (0.132) |
| 3p gain | 40 (8%) | 476 |
0.00012 (0.000767) |
0.0024 (0.00948) |
0.927 (0.974) |
0.741 (0.841) |
0.00021 (0.00117) |
0.00111 (0.00496) |
0.156 (0.275) |
0.124 (0.231) |
0.85 (0.926) |
0.0167 (0.0475) |
||
| 6q gain | 61 (12%) | 455 |
1 (1.00) |
1 (1.00) |
0.0307 (0.077) |
0.0201 (0.0549) |
0.32 (0.461) |
0.781 (0.874) |
0.713 (0.815) |
0.0223 (0.0598) |
0.00455 (0.0163) |
0.00664 (0.0225) |
0.98 (1.00) |
0.159 (0.278) |
| 8p gain | 129 (25%) | 387 |
0.0454 (0.104) |
0.0627 (0.132) |
1e-05 (0.000101) |
0.0038 (0.014) |
0.483 (0.618) |
0.304 (0.446) |
0.00025 (0.00137) |
0.00248 (0.00972) |
0.432 (0.573) |
0.889 (0.952) |
0.311 (0.452) |
0.569 (0.693) |
| 10q gain | 78 (15%) | 438 |
0.00099 (0.00445) |
0.00021 (0.00117) |
0.509 (0.642) |
0.181 (0.302) |
1e-05 (0.000101) |
1e-05 (0.000101) |
0.147 (0.264) |
0.0859 (0.173) |
0.899 (0.957) |
0.0494 (0.111) |
||
| 16p gain | 131 (25%) | 385 |
0.494 (0.627) |
0.785 (0.875) |
0.049 (0.11) |
0.945 (0.987) |
0.186 (0.306) |
0.0893 (0.178) |
0.0377 (0.0902) |
0.0106 (0.033) |
0.0114 (0.0349) |
0.787 (0.876) |
0.0404 (0.0953) |
0.11 (0.209) |
| 19q gain | 76 (15%) | 440 |
0.00046 (0.0023) |
0.00444 (0.016) |
0.956 (0.998) |
0.528 (0.659) |
0.00796 (0.0263) |
0.0264 (0.0683) |
0.17 (0.292) |
0.336 (0.477) |
0.53 (0.66) |
0.00141 (0.00614) |
||
| 18q loss | 212 (41%) | 304 |
0.617 (0.731) |
0.452 (0.588) |
1e-05 (0.000101) |
0.893 (0.953) |
0.011 (0.034) |
0.00013 (0.000805) |
0.00069 (0.00328) |
0.00016 (0.000948) |
0.0912 (0.181) |
0.534 (0.662) |
0.663 (0.767) |
0.222 (0.348) |
| 5q gain | 125 (24%) | 391 |
0.355 (0.496) |
0.518 (0.651) |
0.0466 (0.106) |
0.898 (0.956) |
0.523 (0.656) |
0.279 (0.417) |
0.00297 (0.0112) |
0.0113 (0.0349) |
0.177 (0.298) |
0.0424 (0.099) |
0.553 (0.679) |
0.211 (0.339) |
| 13q gain | 44 (9%) | 472 |
0.414 (0.557) |
0.543 (0.669) |
0.173 (0.295) |
0.0308 (0.077) |
0.0428 (0.0994) |
0.0348 (0.0842) |
0.941 (0.984) |
0.021 (0.0568) |
0.977 (1.00) |
0.369 (0.512) |
0.449 (0.588) |
0.351 (0.492) |
| 15q gain | 38 (7%) | 478 |
0.192 (0.313) |
0.147 (0.264) |
0.00011 (0.000707) |
0.00593 (0.0204) |
0.271 (0.408) |
0.326 (0.466) |
0.0191 (0.0533) |
1e-05 (0.000101) |
0.792 (0.879) |
0.655 (0.763) |
0.227 (0.351) |
1 (1.00) |
| 21q gain | 96 (19%) | 420 |
0.171 (0.292) |
0.054 (0.118) |
0.00026 (0.0014) |
0.964 (1.00) |
0.432 (0.573) |
0.00906 (0.0294) |
0.00021 (0.00117) |
0.00051 (0.00252) |
0.762 (0.859) |
0.785 (0.875) |
0.434 (0.574) |
0.573 (0.695) |
| 1p loss | 83 (16%) | 433 |
0.559 (0.684) |
0.22 (0.346) |
2e-05 (0.000184) |
0.0482 (0.109) |
0.177 (0.298) |
0.341 (0.482) |
0.00023 (0.00127) |
5e-05 (0.00037) |
0.855 (0.929) |
0.341 (0.482) |
0.285 (0.424) |
0.73 (0.833) |
| 3q loss | 146 (28%) | 370 |
0.406 (0.551) |
0.144 (0.262) |
0.0133 (0.0395) |
0.0256 (0.0668) |
1 (1.00) |
0.665 (0.767) |
0.00619 (0.0212) |
0.0225 (0.0601) |
0.22 (0.346) |
0.593 (0.709) |
0.205 (0.331) |
0.854 (0.929) |
| 6p loss | 107 (21%) | 409 |
0.0311 (0.0775) |
0.00759 (0.0251) |
0.0889 (0.178) |
0.033 (0.0813) |
0.218 (0.346) |
0.56 (0.684) |
0.227 (0.351) |
0.366 (0.508) |
0.317 (0.458) |
0.00403 (0.0146) |
0.863 (0.934) |
0.259 (0.393) |
| 6q loss | 217 (42%) | 299 |
0.408 (0.552) |
0.346 (0.487) |
0.0027 (0.0105) |
4e-05 (0.00031) |
0.202 (0.328) |
0.134 (0.247) |
0.276 (0.414) |
0.00089 (0.00411) |
0.664 (0.767) |
0.00096 (0.00437) |
0.839 (0.915) |
0.152 (0.27) |
| 7p loss | 39 (8%) | 477 |
0.293 (0.432) |
0.472 (0.609) |
0.0003 (0.00156) |
0.267 (0.404) |
0.42 (0.562) |
0.764 (0.859) |
0.0464 (0.106) |
0.0133 (0.0395) |
0.581 (0.697) |
0.35 (0.492) |
0.00644 (0.0219) |
0.0626 (0.132) |
| 11p loss | 116 (22%) | 400 |
0.561 (0.685) |
0.307 (0.448) |
0.00016 (0.000948) |
0.029 (0.0739) |
0.641 (0.752) |
0.417 (0.56) |
5e-05 (0.00037) |
0.00061 (0.00299) |
0.0973 (0.19) |
0.14 (0.255) |
0.356 (0.497) |
0.146 (0.263) |
| 11q loss | 91 (18%) | 425 |
0.557 (0.683) |
0.307 (0.448) |
0.00141 (0.00614) |
0.0428 (0.0994) |
0.491 (0.625) |
0.301 (0.441) |
0.00159 (0.00674) |
0.0199 (0.0548) |
0.161 (0.28) |
0.169 (0.29) |
0.158 (0.277) |
0.658 (0.765) |
| xp loss | 105 (20%) | 411 |
0.909 (0.963) |
0.788 (0.876) |
4e-05 (0.00031) |
0.0379 (0.0905) |
0.451 (0.588) |
0.0345 (0.0842) |
0.131 (0.242) |
0.00274 (0.0106) |
0.65 (0.76) |
0.396 (0.546) |
0.438 (0.579) |
0.209 (0.336) |
| 4p gain | 77 (15%) | 439 |
0.901 (0.957) |
0.402 (0.55) |
6e-05 (0.000431) |
0.0123 (0.0372) |
0.753 (0.85) |
0.207 (0.333) |
0.00459 (0.0164) |
0.0829 (0.168) |
0.13 (0.241) |
0.136 (0.251) |
0.796 (0.881) |
0.131 (0.242) |
| 9p gain | 45 (9%) | 471 |
0.00142 (0.00616) |
0.108 (0.204) |
0.763 (0.859) |
0.299 (0.439) |
0.705 (0.809) |
0.00215 (0.00864) |
0.0758 (0.156) |
0.467 (0.604) |
0.0463 (0.106) |
0.137 (0.252) |
||
| 16q gain | 99 (19%) | 417 |
0.596 (0.712) |
0.309 (0.449) |
0.0391 (0.0928) |
0.881 (0.945) |
0.0305 (0.077) |
0.0581 (0.125) |
0.0909 (0.181) |
0.141 (0.257) |
0.0059 (0.0204) |
0.14 (0.255) |
0.212 (0.339) |
0.0959 (0.188) |
| 17p gain | 83 (16%) | 433 |
1 (1.00) |
0.827 (0.908) |
0.00011 (0.000707) |
0.00295 (0.0112) |
1 (1.00) |
0.447 (0.586) |
0.442 (0.583) |
0.0535 (0.118) |
0.00549 (0.0191) |
0.0584 (0.125) |
0.759 (0.857) |
0.446 (0.586) |
| xp gain | 51 (10%) | 465 |
0.401 (0.55) |
0.221 (0.347) |
0.00022 (0.00122) |
0.00316 (0.0119) |
0.333 (0.473) |
0.268 (0.406) |
0.181 (0.302) |
0.0515 (0.115) |
0.0518 (0.115) |
0.0268 (0.069) |
0.893 (0.953) |
0.273 (0.412) |
| 5p loss | 53 (10%) | 463 |
0.575 (0.695) |
0.414 (0.557) |
0.14 (0.255) |
0.076 (0.156) |
0.904 (0.958) |
0.773 (0.868) |
0.0106 (0.033) |
0.149 (0.267) |
0.167 (0.288) |
0.0201 (0.0549) |
0.802 (0.887) |
0.0212 (0.0573) |
| 12p loss | 114 (22%) | 402 |
0.63 (0.745) |
1 (1.00) |
2e-05 (0.000184) |
0.402 (0.55) |
0.0538 (0.118) |
0.239 (0.368) |
0.00034 (0.00173) |
0.00016 (0.000948) |
0.0555 (0.12) |
0.599 (0.715) |
1 (1.00) |
0.285 (0.424) |
| 12q loss | 102 (20%) | 414 |
0.777 (0.87) |
0.827 (0.908) |
1e-05 (0.000101) |
0.0962 (0.188) |
0.177 (0.298) |
0.0983 (0.191) |
3e-05 (0.000248) |
6e-05 (0.000431) |
0.06 (0.128) |
0.189 (0.309) |
0.892 (0.953) |
0.228 (0.351) |
| 14q loss | 114 (22%) | 402 |
0.93 (0.976) |
0.411 (0.554) |
8e-05 (0.000547) |
0.101 (0.195) |
0.331 (0.472) |
0.106 (0.202) |
0.156 (0.275) |
0.00235 (0.00936) |
0.032 (0.0794) |
0.166 (0.287) |
0.212 (0.339) |
0.0617 (0.131) |
| 17q loss | 57 (11%) | 459 |
0.911 (0.963) |
1 (1.00) |
0.00328 (0.0122) |
0.419 (0.562) |
0.0102 (0.0322) |
0.0914 (0.181) |
0.0468 (0.106) |
0.546 (0.671) |
0.748 (0.847) |
0.288 (0.427) |
1 (1.00) |
0.872 (0.939) |
| 18p loss | 178 (34%) | 338 |
0.404 (0.55) |
0.225 (0.35) |
2e-05 (0.000184) |
0.675 (0.777) |
0.0725 (0.15) |
0.0624 (0.132) |
0.0101 (0.0322) |
0.00113 (0.00503) |
0.0793 (0.162) |
0.299 (0.439) |
0.914 (0.963) |
0.666 (0.767) |
| xq loss | 63 (12%) | 453 |
0.175 (0.297) |
0.254 (0.389) |
0.00356 (0.0132) |
0.00166 (0.00692) |
0.56 (0.684) |
0.739 (0.84) |
0.0838 (0.169) |
0.0581 (0.125) |
0.089 (0.178) |
0.00357 (0.0132) |
0.513 (0.646) |
0.174 (0.296) |
| 9q gain | 32 (6%) | 484 |
0.0684 (0.143) |
0.0328 (0.081) |
0.509 (0.642) |
0.612 (0.727) |
0.637 (0.749) |
0.0349 (0.0842) |
0.346 (0.487) |
0.663 (0.767) |
0.442 (0.583) |
0.218 (0.346) |
||
| 22q gain | 62 (12%) | 454 |
0.107 (0.204) |
0.122 (0.227) |
0.00059 (0.0029) |
0.933 (0.978) |
0.107 (0.204) |
0.281 (0.419) |
0.359 (0.5) |
0.0427 (0.0994) |
0.447 (0.586) |
0.565 (0.689) |
0.281 (0.419) |
0.538 (0.665) |
| xq gain | 83 (16%) | 433 |
0.655 (0.763) |
0.245 (0.376) |
0.00014 (0.000861) |
0.0741 (0.153) |
0.869 (0.938) |
0.151 (0.269) |
0.172 (0.294) |
0.0165 (0.0471) |
0.0513 (0.114) |
0.291 (0.43) |
0.223 (0.348) |
0.16 (0.279) |
| 8q loss | 60 (12%) | 456 |
0.0776 (0.159) |
0.094 (0.185) |
0.0194 (0.0538) |
0.496 (0.628) |
0.351 (0.492) |
0.478 (0.614) |
0.0149 (0.0432) |
0.0623 (0.132) |
0.445 (0.586) |
0.824 (0.908) |
0.168 (0.289) |
0.431 (0.573) |
| 4q gain | 44 (9%) | 472 |
0.869 (0.938) |
0.784 (0.875) |
0.0631 (0.132) |
0.871 (0.939) |
0.867 (0.937) |
0.23 (0.355) |
0.00166 (0.00692) |
0.0679 (0.142) |
0.114 (0.213) |
0.178 (0.299) |
0.408 (0.553) |
0.209 (0.336) |
| 1q loss | 33 (6%) | 483 |
0.749 (0.847) |
0.581 (0.697) |
0.573 (0.695) |
0.703 (0.808) |
0.0104 (0.0327) |
0.111 (0.209) |
0.177 (0.298) |
0.914 (0.963) |
0.326 (0.466) |
0.657 (0.764) |
0.481 (0.616) |
0.521 (0.654) |
| 7q loss | 47 (9%) | 469 |
0.57 (0.694) |
0.622 (0.737) |
0.0238 (0.0626) |
0.978 (1.00) |
0.463 (0.6) |
0.545 (0.671) |
0.636 (0.749) |
0.415 (0.558) |
0.403 (0.55) |
0.276 (0.414) |
0.529 (0.659) |
0.637 (0.749) |
| 19p gain | 30 (6%) | 486 |
0.15 (0.268) |
0.22 (0.346) |
0.765 (0.859) |
0.924 (0.973) |
0.501 (0.633) |
0.631 (0.745) |
0.681 (0.783) |
0.829 (0.908) |
0.875 (0.941) |
0.323 (0.463) |
||
| 2p loss | 28 (5%) | 488 |
0.776 (0.87) |
0.323 (0.463) |
0.79 (0.877) |
1 (1.00) |
0.491 (0.625) |
0.98 (1.00) |
0.732 (0.833) |
0.838 (0.915) |
0.165 (0.287) |
0.837 (0.915) |
0.16 (0.279) |
0.279 (0.417) |
| 2q loss | 29 (6%) | 487 |
0.491 (0.625) |
0.18 (0.3) |
0.101 (0.196) |
0.638 (0.75) |
0.531 (0.66) |
0.473 (0.609) |
0.293 (0.432) |
0.399 (0.548) |
0.088 (0.177) |
0.525 (0.656) |
0.494 (0.627) |
0.374 (0.518) |
| 20q loss | 69 (13%) | 447 |
0.258 (0.393) |
0.0998 (0.194) |
0.615 (0.73) |
0.968 (1.00) |
0.072 (0.15) |
0.226 (0.351) |
0.58 (0.696) |
0.149 (0.267) |
0.94 (0.984) |
0.824 (0.908) |
0.166 (0.287) |
0.958 (0.998) |
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S1. Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 1P GAIN MUTATED | 12 | 50 | 19 | 69 |
| 1P GAIN WILD-TYPE | 57 | 178 | 60 | 71 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0236 (Fisher's exact test), Q value = 0.062
Table S2. Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 1P GAIN MUTATED | 14 | 32 | 14 |
| 1P GAIN WILD-TYPE | 30 | 41 | 50 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0181 (Fisher's exact test), Q value = 0.051
Table S3. Gene #1: '1p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 1P GAIN MUTATED | 18 | 6 | 21 | 7 | 8 |
| 1P GAIN WILD-TYPE | 22 | 27 | 24 | 24 | 24 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.033 (Fisher's exact test), Q value = 0.081
Table S4. Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 1P GAIN MUTATED | 44 | 70 | 36 |
| 1P GAIN WILD-TYPE | 122 | 125 | 115 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.033
Table S5. Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 1P GAIN MUTATED | 20 | 40 | 39 | 8 | 9 | 14 | 20 |
| 1P GAIN WILD-TYPE | 58 | 70 | 58 | 40 | 44 | 35 | 57 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0362 (Fisher's exact test), Q value = 0.087
Table S6. Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 1P GAIN MUTATED | 45 | 67 | 36 |
| 1P GAIN WILD-TYPE | 144 | 161 | 57 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00392 (Fisher's exact test), Q value = 0.014
Table S7. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 1Q GAIN MUTATED | 50 | 121 | 44 | 95 |
| 1Q GAIN WILD-TYPE | 19 | 107 | 35 | 45 |
Figure S7. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00131 (Fisher's exact test), Q value = 0.0058
Table S8. Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 1Q GAIN MUTATED | 70 | 98 | 109 |
| 1Q GAIN WILD-TYPE | 74 | 51 | 53 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00326 (Fisher's exact test), Q value = 0.012
Table S9. Gene #2: '1q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 1Q GAIN MUTATED | 37 | 46 | 34 |
| 1Q GAIN WILD-TYPE | 7 | 27 | 30 |
Figure S9. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0261 (Fisher's exact test), Q value = 0.068
Table S10. Gene #2: '1q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 1Q GAIN MUTATED | 29 | 23 | 27 | 13 | 25 |
| 1Q GAIN WILD-TYPE | 11 | 10 | 18 | 18 | 7 |
Figure S10. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00268 (Fisher's exact test), Q value = 0.01
Table S11. Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 1Q GAIN MUTATED | 97 | 103 | 107 |
| 1Q GAIN WILD-TYPE | 69 | 92 | 44 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0271 (Fisher's exact test), Q value = 0.07
Table S12. Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 1Q GAIN MUTATED | 49 | 61 | 53 | 37 | 38 | 30 | 39 |
| 1Q GAIN WILD-TYPE | 29 | 49 | 44 | 11 | 15 | 19 | 38 |
Figure S12. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0283 (Fisher's exact test), Q value = 0.072
Table S13. Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 1Q GAIN MUTATED | 50 | 126 | 72 | 58 |
| 1Q GAIN WILD-TYPE | 21 | 72 | 69 | 42 |
Figure S13. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0314 (Fisher's exact test), Q value = 0.078
Table S14. Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 1Q GAIN MUTATED | 90 | 130 | 45 |
| 1Q GAIN WILD-TYPE | 55 | 68 | 46 |
Figure S14. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S15. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 2P GAIN MUTATED | 28 | 35 | 37 | 53 |
| 2P GAIN WILD-TYPE | 41 | 193 | 42 | 87 |
Figure S15. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S16. Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 2P GAIN MUTATED | 20 | 60 | 49 |
| 2P GAIN WILD-TYPE | 124 | 89 | 113 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00202 (Fisher's exact test), Q value = 0.0082
Table S17. Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 2P GAIN MUTATED | 33 | 66 | 54 |
| 2P GAIN WILD-TYPE | 133 | 129 | 97 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0015
Table S18. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 2P GAIN MUTATED | 16 | 31 | 34 | 8 | 25 | 23 | 16 |
| 2P GAIN WILD-TYPE | 62 | 79 | 63 | 40 | 28 | 26 | 61 |
Figure S18. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S19. Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 2P GAIN MUTATED | 40 | 93 | 19 |
| 2P GAIN WILD-TYPE | 149 | 135 | 74 |
Figure S19. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00137 (Fisher's exact test), Q value = 0.006
Table S20. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 2P GAIN MUTATED | 14 | 67 | 30 | 41 |
| 2P GAIN WILD-TYPE | 57 | 131 | 111 | 59 |
Figure S20. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00015 (Fisher's exact test), Q value = 0.00092
Table S21. Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 2P GAIN MUTATED | 16 | 91 | 19 |
| 2P GAIN WILD-TYPE | 87 | 157 | 64 |
Figure S21. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.018 (Fisher's exact test), Q value = 0.051
Table S22. Gene #4: '2q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 2Q GAIN MUTATED | 0 | 2 | 3 | 5 |
| 2Q GAIN WILD-TYPE | 5 | 7 | 9 | 1 |
Figure S22. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0442 (Fisher's exact test), Q value = 0.1
Table S23. Gene #4: '2q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 2Q GAIN MUTATED | 3 | 2 | 5 |
| 2Q GAIN WILD-TYPE | 11 | 9 | 2 |
Figure S23. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S24. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 2Q GAIN MUTATED | 25 | 36 | 35 | 45 |
| 2Q GAIN WILD-TYPE | 44 | 192 | 44 | 95 |
Figure S24. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0016
Table S25. Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 2Q GAIN MUTATED | 21 | 50 | 49 |
| 2Q GAIN WILD-TYPE | 123 | 99 | 113 |
Figure S25. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0386 (Fisher's exact test), Q value = 0.092
Table S26. Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 2Q GAIN MUTATED | 35 | 55 | 51 |
| 2Q GAIN WILD-TYPE | 131 | 140 | 100 |
Figure S26. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0191 (Fisher's exact test), Q value = 0.053
Table S27. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 2Q GAIN MUTATED | 15 | 28 | 33 | 12 | 18 | 21 | 14 |
| 2Q GAIN WILD-TYPE | 63 | 82 | 64 | 36 | 35 | 28 | 63 |
Figure S27. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00257 (Fisher's exact test), Q value = 0.01
Table S28. Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 2Q GAIN MUTATED | 41 | 80 | 19 |
| 2Q GAIN WILD-TYPE | 148 | 148 | 74 |
Figure S28. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0344 (Fisher's exact test), Q value = 0.084
Table S29. Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 2Q GAIN MUTATED | 38 | 61 | 15 |
| 2Q GAIN WILD-TYPE | 107 | 137 | 76 |
Figure S29. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.033
Table S30. Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 2Q GAIN MUTATED | 17 | 78 | 19 |
| 2Q GAIN WILD-TYPE | 86 | 170 | 64 |
Figure S30. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00077
Table S31. Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 3P GAIN MUTATED | 10 | 5 | 7 | 18 |
| 3P GAIN WILD-TYPE | 59 | 223 | 72 | 122 |
Figure S31. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0024 (Fisher's exact test), Q value = 0.0095
Table S32. Gene #5: '3p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 3P GAIN MUTATED | 3 | 14 | 19 |
| 3P GAIN WILD-TYPE | 141 | 135 | 143 |
Figure S32. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0012
Table S33. Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 3P GAIN MUTATED | 4 | 27 | 9 |
| 3P GAIN WILD-TYPE | 162 | 168 | 142 |
Figure S33. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00111 (Fisher's exact test), Q value = 0.005
Table S34. Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3P GAIN MUTATED | 3 | 13 | 17 | 1 | 2 | 2 | 2 |
| 3P GAIN WILD-TYPE | 75 | 97 | 80 | 47 | 51 | 47 | 75 |
Figure S34. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0167 (Fisher's exact test), Q value = 0.047
Table S35. Gene #5: '3p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 3P GAIN MUTATED | 2 | 24 | 9 |
| 3P GAIN WILD-TYPE | 101 | 224 | 74 |
Figure S35. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00043
Table S36. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 3Q GAIN MUTATED | 13 | 20 | 23 | 33 |
| 3Q GAIN WILD-TYPE | 56 | 208 | 56 | 107 |
Figure S36. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0017
Table S37. Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 3Q GAIN MUTATED | 12 | 38 | 29 |
| 3Q GAIN WILD-TYPE | 132 | 111 | 133 |
Figure S37. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S38. Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 3Q GAIN MUTATED | 13 | 51 | 25 |
| 3Q GAIN WILD-TYPE | 153 | 144 | 126 |
Figure S38. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S39. Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3Q GAIN MUTATED | 4 | 22 | 41 | 2 | 6 | 8 | 6 |
| 3Q GAIN WILD-TYPE | 74 | 88 | 56 | 46 | 47 | 41 | 71 |
Figure S39. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00742 (Fisher's exact test), Q value = 0.025
Table S40. Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 3Q GAIN MUTATED | 26 | 53 | 10 |
| 3Q GAIN WILD-TYPE | 163 | 175 | 83 |
Figure S40. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0287 (Fisher's exact test), Q value = 0.073
Table S41. Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 3Q GAIN MUTATED | 8 | 37 | 18 | 26 |
| 3Q GAIN WILD-TYPE | 63 | 161 | 123 | 74 |
Figure S41. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0016 (Fisher's exact test), Q value = 0.0068
Table S42. Gene #6: '3q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 3Q GAIN MUTATED | 8 | 57 | 13 |
| 3Q GAIN WILD-TYPE | 95 | 191 | 70 |
Figure S42. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00043
Table S43. Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 4P GAIN MUTATED | 10 | 17 | 20 | 30 |
| 4P GAIN WILD-TYPE | 59 | 211 | 59 | 110 |
Figure S43. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0123 (Fisher's exact test), Q value = 0.037
Table S44. Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 4P GAIN MUTATED | 13 | 32 | 25 |
| 4P GAIN WILD-TYPE | 131 | 117 | 137 |
Figure S44. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00459 (Fisher's exact test), Q value = 0.016
Table S45. Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 4P GAIN MUTATED | 16 | 42 | 19 |
| 4P GAIN WILD-TYPE | 150 | 153 | 132 |
Figure S45. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00166 (Fisher's exact test), Q value = 0.0069
Table S46. Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 4Q GAIN MUTATED | 12 | 27 | 5 |
| 4Q GAIN WILD-TYPE | 154 | 168 | 146 |
Figure S46. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S47. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 5P GAIN MUTATED | 43 | 90 | 37 | 100 |
| 5P GAIN WILD-TYPE | 26 | 138 | 42 | 40 |
Figure S47. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00814 (Fisher's exact test), Q value = 0.027
Table S48. Gene #9: '5p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 5P GAIN MUTATED | 62 | 90 | 91 |
| 5P GAIN WILD-TYPE | 82 | 59 | 71 |
Figure S48. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00738 (Fisher's exact test), Q value = 0.025
Table S49. Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 5P GAIN MUTATED | 42 | 64 | 58 | 16 | 32 | 26 | 30 |
| 5P GAIN WILD-TYPE | 36 | 46 | 39 | 32 | 21 | 23 | 47 |
Figure S49. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0332 (Fisher's exact test), Q value = 0.081
Table S50. Gene #9: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 5P GAIN MUTATED | 86 | 133 | 49 |
| 5P GAIN WILD-TYPE | 103 | 95 | 44 |
Figure S50. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0432 (Fisher's exact test), Q value = 0.1
Table S51. Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 5P GAIN MUTATED | 36 | 111 | 61 | 60 |
| 5P GAIN WILD-TYPE | 35 | 87 | 80 | 40 |
Figure S51. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S52. Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 5P GAIN MUTATED | 36 | 152 | 48 |
| 5P GAIN WILD-TYPE | 67 | 96 | 35 |
Figure S52. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0466 (Fisher's exact test), Q value = 0.11
Table S53. Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 5Q GAIN MUTATED | 16 | 55 | 11 | 43 |
| 5Q GAIN WILD-TYPE | 53 | 173 | 68 | 97 |
Figure S53. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00297 (Fisher's exact test), Q value = 0.011
Table S54. Gene #10: '5q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 5Q GAIN MUTATED | 55 | 42 | 26 |
| 5Q GAIN WILD-TYPE | 111 | 153 | 125 |
Figure S54. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.035
Table S55. Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 5Q GAIN MUTATED | 32 | 20 | 26 | 10 | 12 | 10 | 13 |
| 5Q GAIN WILD-TYPE | 46 | 90 | 71 | 38 | 41 | 39 | 64 |
Figure S55. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0424 (Fisher's exact test), Q value = 0.099
Table S56. Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 5Q GAIN MUTATED | 26 | 41 | 37 | 20 |
| 5Q GAIN WILD-TYPE | 45 | 157 | 104 | 80 |
Figure S56. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0332 (Fisher's exact test), Q value = 0.081
Table S57. Gene #11: '6p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 6P GAIN MUTATED | 4 | 1 | 5 |
| 6P GAIN WILD-TYPE | 10 | 10 | 2 |
Figure S57. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00277 (Fisher's exact test), Q value = 0.011
Table S58. Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 6P GAIN MUTATED | 29 | 47 | 22 | 45 |
| 6P GAIN WILD-TYPE | 40 | 181 | 57 | 95 |
Figure S58. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00049
Table S59. Gene #11: '6p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 6P GAIN MUTATED | 22 | 56 | 46 |
| 6P GAIN WILD-TYPE | 122 | 93 | 116 |
Figure S59. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00676 (Fisher's exact test), Q value = 0.023
Table S60. Gene #11: '6p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 6P GAIN MUTATED | 18 | 12 | 22 |
| 6P GAIN WILD-TYPE | 26 | 61 | 42 |
Figure S60. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0182 (Fisher's exact test), Q value = 0.051
Table S61. Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 6P GAIN MUTATED | 17 | 25 | 38 | 18 | 17 | 14 | 14 |
| 6P GAIN WILD-TYPE | 61 | 85 | 59 | 30 | 36 | 35 | 63 |
Figure S61. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00527 (Fisher's exact test), Q value = 0.019
Table S62. Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 6P GAIN MUTATED | 15 | 64 | 26 | 35 |
| 6P GAIN WILD-TYPE | 56 | 134 | 115 | 65 |
Figure S62. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0137 (Fisher's exact test), Q value = 0.04
Table S63. Gene #11: '6p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 6P GAIN MUTATED | 17 | 78 | 23 |
| 6P GAIN WILD-TYPE | 86 | 170 | 60 |
Figure S63. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0307 (Fisher's exact test), Q value = 0.077
Table S64. Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 6Q GAIN MUTATED | 10 | 17 | 10 | 24 |
| 6Q GAIN WILD-TYPE | 59 | 211 | 69 | 116 |
Figure S64. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0201 (Fisher's exact test), Q value = 0.055
Table S65. Gene #12: '6q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 6Q GAIN MUTATED | 10 | 26 | 17 |
| 6Q GAIN WILD-TYPE | 134 | 123 | 145 |
Figure S65. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.06
Table S66. Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 6Q GAIN MUTATED | 11 | 7 | 20 | 5 | 8 | 6 | 4 |
| 6Q GAIN WILD-TYPE | 67 | 103 | 77 | 43 | 45 | 43 | 73 |
Figure S66. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00455 (Fisher's exact test), Q value = 0.016
Table S67. Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 6Q GAIN MUTATED | 12 | 38 | 10 |
| 6Q GAIN WILD-TYPE | 177 | 190 | 83 |
Figure S67. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00664 (Fisher's exact test), Q value = 0.022
Table S68. Gene #12: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 6Q GAIN MUTATED | 3 | 30 | 10 | 17 |
| 6Q GAIN WILD-TYPE | 68 | 168 | 131 | 83 |
Figure S68. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S69. Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 7P GAIN MUTATED | 26 | 79 | 43 | 111 |
| 7P GAIN WILD-TYPE | 43 | 149 | 36 | 29 |
Figure S69. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0155 (Fisher's exact test), Q value = 0.044
Table S70. Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 7P GAIN MUTATED | 60 | 72 | 94 |
| 7P GAIN WILD-TYPE | 84 | 77 | 68 |
Figure S70. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00097 (Fisher's exact test), Q value = 0.0044
Table S71. Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 7P GAIN MUTATED | 11 | 44 | 33 |
| 7P GAIN WILD-TYPE | 33 | 29 | 31 |
Figure S71. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.014 (Fisher's exact test), Q value = 0.041
Table S72. Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 7P GAIN MUTATED | 22 | 12 | 30 | 14 | 10 |
| 7P GAIN WILD-TYPE | 18 | 21 | 15 | 17 | 22 |
Figure S72. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S73. Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 7P GAIN MUTATED | 71 | 131 | 54 |
| 7P GAIN WILD-TYPE | 95 | 64 | 97 |
Figure S73. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S74. Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 7P GAIN MUTATED | 31 | 78 | 58 | 8 | 22 | 28 | 31 |
| 7P GAIN WILD-TYPE | 47 | 32 | 39 | 40 | 31 | 21 | 46 |
Figure S74. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S75. Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 7P GAIN MUTATED | 69 | 126 | 61 |
| 7P GAIN WILD-TYPE | 120 | 102 | 32 |
Figure S75. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00037
Table S76. Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 7P GAIN MUTATED | 21 | 118 | 62 | 55 |
| 7P GAIN WILD-TYPE | 50 | 80 | 79 | 45 |
Figure S76. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00037
Table S77. Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 7P GAIN MUTATED | 59 | 101 | 64 |
| 7P GAIN WILD-TYPE | 86 | 97 | 27 |
Figure S77. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S78. Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 7P GAIN MUTATED | 28 | 146 | 50 |
| 7P GAIN WILD-TYPE | 75 | 102 | 33 |
Figure S78. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S79. Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 7Q GAIN MUTATED | 18 | 67 | 35 | 92 |
| 7Q GAIN WILD-TYPE | 51 | 161 | 44 | 48 |
Figure S79. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S80. Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 7Q GAIN MUTATED | 59 | 107 | 43 |
| 7Q GAIN WILD-TYPE | 107 | 88 | 108 |
Figure S80. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S81. Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 7Q GAIN MUTATED | 25 | 69 | 43 | 6 | 17 | 23 | 26 |
| 7Q GAIN WILD-TYPE | 53 | 41 | 54 | 42 | 36 | 26 | 51 |
Figure S81. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00503 (Fisher's exact test), Q value = 0.018
Table S82. Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 7Q GAIN MUTATED | 61 | 101 | 47 |
| 7Q GAIN WILD-TYPE | 128 | 127 | 46 |
Figure S82. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00073 (Fisher's exact test), Q value = 0.0035
Table S83. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 7Q GAIN MUTATED | 18 | 99 | 48 | 44 |
| 7Q GAIN WILD-TYPE | 53 | 99 | 93 | 56 |
Figure S83. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S84. Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 7Q GAIN MUTATED | 21 | 119 | 40 |
| 7Q GAIN WILD-TYPE | 82 | 129 | 43 |
Figure S84. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0454 (Fisher's exact test), Q value = 0.1
Table S85. Gene #15: '8p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 8P GAIN MUTATED | 0 | 1 | 2 | 4 |
| 8P GAIN WILD-TYPE | 5 | 8 | 10 | 2 |
Figure S85. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S86. Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 8P GAIN MUTATED | 39 | 38 | 22 | 30 |
| 8P GAIN WILD-TYPE | 30 | 190 | 57 | 110 |
Figure S86. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0038 (Fisher's exact test), Q value = 0.014
Table S87. Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 8P GAIN MUTATED | 25 | 51 | 38 |
| 8P GAIN WILD-TYPE | 119 | 98 | 124 |
Figure S87. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00025 (Fisher's exact test), Q value = 0.0014
Table S88. Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 8P GAIN MUTATED | 34 | 37 | 56 |
| 8P GAIN WILD-TYPE | 132 | 158 | 95 |
Figure S88. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00248 (Fisher's exact test), Q value = 0.0097
Table S89. Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 8P GAIN MUTATED | 15 | 23 | 21 | 15 | 25 | 15 | 13 |
| 8P GAIN WILD-TYPE | 63 | 87 | 76 | 33 | 28 | 34 | 64 |
Figure S89. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0349 (Fisher's exact test), Q value = 0.084
Table S90. Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 8Q GAIN MUTATED | 3 | 3 | 2 | 5 |
| 8Q GAIN WILD-TYPE | 2 | 6 | 10 | 1 |
Figure S90. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0199 (Fisher's exact test), Q value = 0.055
Table S91. Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 8Q GAIN MUTATED | 3 | 4 | 6 |
| 8Q GAIN WILD-TYPE | 11 | 7 | 1 |
Figure S91. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S92. Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 8Q GAIN MUTATED | 61 | 66 | 47 | 70 |
| 8Q GAIN WILD-TYPE | 8 | 162 | 32 | 70 |
Figure S92. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S93. Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 8Q GAIN MUTATED | 43 | 86 | 87 |
| 8Q GAIN WILD-TYPE | 101 | 63 | 75 |
Figure S93. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S94. Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 8Q GAIN MUTATED | 59 | 92 | 90 |
| 8Q GAIN WILD-TYPE | 107 | 103 | 61 |
Figure S94. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S95. Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 8Q GAIN MUTATED | 30 | 51 | 49 | 20 | 43 | 26 | 22 |
| 8Q GAIN WILD-TYPE | 48 | 59 | 48 | 28 | 10 | 23 | 55 |
Figure S95. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S96. Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 8Q GAIN MUTATED | 63 | 131 | 48 |
| 8Q GAIN WILD-TYPE | 126 | 97 | 45 |
Figure S96. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00158 (Fisher's exact test), Q value = 0.0067
Table S97. Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 8Q GAIN MUTATED | 26 | 108 | 53 | 55 |
| 8Q GAIN WILD-TYPE | 45 | 90 | 88 | 45 |
Figure S97. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00811 (Fisher's exact test), Q value = 0.027
Table S98. Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 8Q GAIN MUTATED | 56 | 110 | 45 |
| 8Q GAIN WILD-TYPE | 89 | 88 | 46 |
Figure S98. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S99. Gene #16: '8q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 8Q GAIN MUTATED | 31 | 143 | 37 |
| 8Q GAIN WILD-TYPE | 72 | 105 | 46 |
Figure S99. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00142 (Fisher's exact test), Q value = 0.0062
Table S100. Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 9P GAIN MUTATED | 13 | 10 | 6 | 16 |
| 9P GAIN WILD-TYPE | 56 | 218 | 73 | 124 |
Figure S100. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00215 (Fisher's exact test), Q value = 0.0086
Table S101. Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9P GAIN MUTATED | 1 | 11 | 13 | 2 | 10 | 1 | 6 |
| 9P GAIN WILD-TYPE | 77 | 99 | 84 | 46 | 43 | 48 | 71 |
Figure S101. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0463 (Fisher's exact test), Q value = 0.11
Table S102. Gene #17: '9p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 9P GAIN MUTATED | 9 | 27 | 6 |
| 9P GAIN WILD-TYPE | 136 | 171 | 85 |
Figure S102. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0328 (Fisher's exact test), Q value = 0.081
Table S103. Gene #18: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 9Q GAIN MUTATED | 7 | 17 | 7 |
| 9Q GAIN WILD-TYPE | 137 | 132 | 155 |
Figure S103. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0349 (Fisher's exact test), Q value = 0.084
Table S104. Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9Q GAIN MUTATED | 1 | 5 | 12 | 2 | 6 | 2 | 3 |
| 9Q GAIN WILD-TYPE | 77 | 105 | 85 | 46 | 47 | 47 | 74 |
Figure S104. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S105. Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 10P GAIN MUTATED | 29 | 25 | 23 | 34 |
| 10P GAIN WILD-TYPE | 40 | 203 | 56 | 106 |
Figure S105. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S106. Gene #19: '10p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 10P GAIN MUTATED | 10 | 45 | 44 |
| 10P GAIN WILD-TYPE | 134 | 104 | 118 |
Figure S106. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S107. Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 10P GAIN MUTATED | 15 | 40 | 55 |
| 10P GAIN WILD-TYPE | 151 | 155 | 96 |
Figure S107. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S108. Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10P GAIN MUTATED | 5 | 19 | 20 | 14 | 25 | 18 | 9 |
| 10P GAIN WILD-TYPE | 73 | 91 | 77 | 34 | 28 | 31 | 68 |
Figure S108. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-04 (Fisher's exact test), Q value = 0.0011
Table S109. Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 10P GAIN MUTATED | 25 | 67 | 17 |
| 10P GAIN WILD-TYPE | 164 | 161 | 76 |
Figure S109. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 8e-04
Table S110. Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 10P GAIN MUTATED | 12 | 56 | 14 | 27 |
| 10P GAIN WILD-TYPE | 59 | 142 | 127 | 73 |
Figure S110. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00081 (Fisher's exact test), Q value = 0.0038
Table S111. Gene #19: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 10P GAIN MUTATED | 11 | 70 | 16 |
| 10P GAIN WILD-TYPE | 92 | 178 | 67 |
Figure S111. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00099 (Fisher's exact test), Q value = 0.0044
Table S112. Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 10Q GAIN MUTATED | 20 | 22 | 16 | 20 |
| 10Q GAIN WILD-TYPE | 49 | 206 | 63 | 120 |
Figure S112. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0012
Table S113. Gene #20: '10q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 10Q GAIN MUTATED | 8 | 29 | 32 |
| 10Q GAIN WILD-TYPE | 136 | 120 | 130 |
Figure S113. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S114. Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 10Q GAIN MUTATED | 11 | 25 | 41 |
| 10Q GAIN WILD-TYPE | 155 | 170 | 110 |
Figure S114. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S115. Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10Q GAIN MUTATED | 3 | 15 | 8 | 13 | 18 | 14 | 6 |
| 10Q GAIN WILD-TYPE | 75 | 95 | 89 | 35 | 35 | 35 | 71 |
Figure S115. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0494 (Fisher's exact test), Q value = 0.11
Table S116. Gene #20: '10q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 10Q GAIN MUTATED | 9 | 47 | 12 |
| 10Q GAIN WILD-TYPE | 94 | 201 | 71 |
Figure S116. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00964 (Fisher's exact test), Q value = 0.031
Table S117. Gene #21: '11p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 11P GAIN MUTATED | 0 | 0 | 2 | 4 |
| 11P GAIN WILD-TYPE | 5 | 9 | 10 | 2 |
Figure S117. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0096 (Fisher's exact test), Q value = 0.031
Table S118. Gene #21: '11p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 11P GAIN MUTATED | 2 | 0 | 4 |
| 11P GAIN WILD-TYPE | 12 | 11 | 3 |
Figure S118. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 6e-04
Table S119. Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 11P GAIN MUTATED | 18 | 23 | 15 | 38 |
| 11P GAIN WILD-TYPE | 51 | 205 | 64 | 102 |
Figure S119. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0155 (Fisher's exact test), Q value = 0.044
Table S120. Gene #21: '11p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 11P GAIN MUTATED | 3 | 20 | 16 |
| 11P GAIN WILD-TYPE | 41 | 53 | 48 |
Figure S120. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0017
Table S121. Gene #21: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11P GAIN MUTATED | 18 | 17 | 29 | 2 | 14 | 7 | 7 |
| 11P GAIN WILD-TYPE | 60 | 93 | 68 | 46 | 39 | 42 | 70 |
Figure S121. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00145 (Fisher's exact test), Q value = 0.0063
Table S122. Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 11P GAIN MUTATED | 20 | 50 | 23 |
| 11P GAIN WILD-TYPE | 169 | 178 | 70 |
Figure S122. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S123. Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 11P GAIN MUTATED | 4 | 40 | 16 | 33 |
| 11P GAIN WILD-TYPE | 67 | 158 | 125 | 67 |
Figure S123. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0155 (Fisher's exact test), Q value = 0.044
Table S124. Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 11P GAIN MUTATED | 10 | 47 | 21 |
| 11P GAIN WILD-TYPE | 93 | 201 | 62 |
Figure S124. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00066 (Fisher's exact test), Q value = 0.0032
Table S125. Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 11Q GAIN MUTATED | 0 | 0 | 2 | 5 |
| 11Q GAIN WILD-TYPE | 5 | 9 | 10 | 1 |
Figure S125. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00092 (Fisher's exact test), Q value = 0.0042
Table S126. Gene #22: '11q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 11Q GAIN MUTATED | 2 | 0 | 5 |
| 11Q GAIN WILD-TYPE | 12 | 11 | 2 |
Figure S126. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S127. Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 11Q GAIN MUTATED | 16 | 26 | 18 | 54 |
| 11Q GAIN WILD-TYPE | 53 | 202 | 61 | 86 |
Figure S127. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0439 (Fisher's exact test), Q value = 0.1
Table S128. Gene #22: '11q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 11Q GAIN MUTATED | 23 | 32 | 45 |
| 11Q GAIN WILD-TYPE | 121 | 117 | 117 |
Figure S128. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0209 (Fisher's exact test), Q value = 0.057
Table S129. Gene #22: '11q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 11Q GAIN MUTATED | 4 | 20 | 19 |
| 11Q GAIN WILD-TYPE | 40 | 53 | 45 |
Figure S129. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00025 (Fisher's exact test), Q value = 0.0014
Table S130. Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11Q GAIN MUTATED | 19 | 30 | 28 | 1 | 16 | 10 | 10 |
| 11Q GAIN WILD-TYPE | 59 | 80 | 69 | 47 | 37 | 39 | 67 |
Figure S130. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00035 (Fisher's exact test), Q value = 0.0018
Table S131. Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 11Q GAIN MUTATED | 24 | 59 | 28 |
| 11Q GAIN WILD-TYPE | 165 | 169 | 65 |
Figure S131. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S132. Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 11Q GAIN MUTATED | 4 | 51 | 22 | 34 |
| 11Q GAIN WILD-TYPE | 67 | 147 | 119 | 66 |
Figure S132. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00507 (Fisher's exact test), Q value = 0.018
Table S133. Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 11Q GAIN MUTATED | 12 | 62 | 24 |
| 11Q GAIN WILD-TYPE | 91 | 186 | 59 |
Figure S133. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0193 (Fisher's exact test), Q value = 0.054
Table S134. Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 12P GAIN MUTATED | 1 | 1 | 4 |
| 12P GAIN WILD-TYPE | 13 | 10 | 3 |
Figure S134. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S135. Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 12P GAIN MUTATED | 22 | 33 | 50 | 32 |
| 12P GAIN WILD-TYPE | 47 | 195 | 29 | 108 |
Figure S135. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0014
Table S136. Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 12P GAIN MUTATED | 24 | 56 | 41 |
| 12P GAIN WILD-TYPE | 120 | 93 | 121 |
Figure S136. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0236 (Fisher's exact test), Q value = 0.062
Table S137. Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 12P GAIN MUTATED | 4 | 22 | 14 |
| 12P GAIN WILD-TYPE | 40 | 51 | 50 |
Figure S137. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S138. Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 12P GAIN MUTATED | 21 | 61 | 55 |
| 12P GAIN WILD-TYPE | 145 | 134 | 96 |
Figure S138. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S139. Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12P GAIN MUTATED | 8 | 27 | 30 | 4 | 29 | 26 | 13 |
| 12P GAIN WILD-TYPE | 70 | 83 | 67 | 44 | 24 | 23 | 64 |
Figure S139. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S140. Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 12P GAIN MUTATED | 30 | 83 | 22 |
| 12P GAIN WILD-TYPE | 159 | 145 | 71 |
Figure S140. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S141. Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 12P GAIN MUTATED | 10 | 56 | 22 | 47 |
| 12P GAIN WILD-TYPE | 61 | 142 | 119 | 53 |
Figure S141. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S142. Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 12P GAIN MUTATED | 10 | 89 | 19 |
| 12P GAIN WILD-TYPE | 93 | 159 | 64 |
Figure S142. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.02 (Fisher's exact test), Q value = 0.055
Table S143. Gene #24: '12q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 12Q GAIN MUTATED | 1 | 1 | 4 |
| 12Q GAIN WILD-TYPE | 13 | 10 | 3 |
Figure S143. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S144. Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 12Q GAIN MUTATED | 26 | 30 | 50 | 24 |
| 12Q GAIN WILD-TYPE | 43 | 198 | 29 | 116 |
Figure S144. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S145. Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 12Q GAIN MUTATED | 20 | 56 | 38 |
| 12Q GAIN WILD-TYPE | 124 | 93 | 124 |
Figure S145. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S146. Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 12Q GAIN MUTATED | 16 | 50 | 64 |
| 12Q GAIN WILD-TYPE | 150 | 145 | 87 |
Figure S146. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S147. Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12Q GAIN MUTATED | 9 | 25 | 25 | 4 | 33 | 27 | 7 |
| 12Q GAIN WILD-TYPE | 69 | 85 | 72 | 44 | 20 | 22 | 70 |
Figure S147. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S148. Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 12Q GAIN MUTATED | 28 | 81 | 19 |
| 12Q GAIN WILD-TYPE | 161 | 147 | 74 |
Figure S148. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S149. Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 12Q GAIN MUTATED | 12 | 58 | 15 | 43 |
| 12Q GAIN WILD-TYPE | 59 | 140 | 126 | 57 |
Figure S149. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S150. Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 12Q GAIN MUTATED | 8 | 85 | 19 |
| 12Q GAIN WILD-TYPE | 95 | 163 | 64 |
Figure S150. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0308 (Fisher's exact test), Q value = 0.077
Table S151. Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 13Q GAIN MUTATED | 5 | 17 | 13 |
| 13Q GAIN WILD-TYPE | 139 | 132 | 149 |
Figure S151. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0428 (Fisher's exact test), Q value = 0.099
Table S152. Gene #25: '13q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 13Q GAIN MUTATED | 8 | 3 | 5 |
| 13Q GAIN WILD-TYPE | 36 | 70 | 59 |
Figure S152. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0348 (Fisher's exact test), Q value = 0.084
Table S153. Gene #25: '13q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 13Q GAIN MUTATED | 6 | 5 | 0 | 3 | 2 |
| 13Q GAIN WILD-TYPE | 34 | 28 | 45 | 28 | 30 |
Figure S153. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.021 (Fisher's exact test), Q value = 0.057
Table S154. Gene #25: '13q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 13Q GAIN MUTATED | 8 | 4 | 10 | 8 | 3 | 8 | 3 |
| 13Q GAIN WILD-TYPE | 70 | 106 | 87 | 40 | 50 | 41 | 74 |
Figure S154. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S155. Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 14Q GAIN MUTATED | 35 | 36 | 15 | 44 |
| 14Q GAIN WILD-TYPE | 34 | 192 | 64 | 96 |
Figure S155. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0123 (Fisher's exact test), Q value = 0.037
Table S156. Gene #26: '14q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 14Q GAIN MUTATED | 27 | 50 | 38 |
| 14Q GAIN WILD-TYPE | 117 | 99 | 124 |
Figure S156. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0488 (Fisher's exact test), Q value = 0.11
Table S157. Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 14Q GAIN MUTATED | 31 | 53 | 45 |
| 14Q GAIN WILD-TYPE | 135 | 142 | 106 |
Figure S157. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S158. Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 14Q GAIN MUTATED | 16 | 23 | 43 | 8 | 23 | 7 | 9 |
| 14Q GAIN WILD-TYPE | 62 | 87 | 54 | 40 | 30 | 42 | 68 |
Figure S158. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 8e-04
Table S159. Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 14Q GAIN MUTATED | 28 | 65 | 33 |
| 14Q GAIN WILD-TYPE | 161 | 163 | 60 |
Figure S159. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00063 (Fisher's exact test), Q value = 0.0031
Table S160. Gene #26: '14q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 14Q GAIN MUTATED | 12 | 61 | 21 | 32 |
| 14Q GAIN WILD-TYPE | 59 | 137 | 120 | 68 |
Figure S160. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.00071
Table S161. Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 15Q GAIN MUTATED | 2 | 12 | 17 | 7 |
| 15Q GAIN WILD-TYPE | 67 | 216 | 62 | 133 |
Figure S161. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00593 (Fisher's exact test), Q value = 0.02
Table S162. Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 15Q GAIN MUTATED | 7 | 18 | 5 |
| 15Q GAIN WILD-TYPE | 137 | 131 | 157 |
Figure S162. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0191 (Fisher's exact test), Q value = 0.053
Table S163. Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 15Q GAIN MUTATED | 10 | 9 | 19 |
| 15Q GAIN WILD-TYPE | 156 | 186 | 132 |
Figure S163. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S164. Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 15Q GAIN MUTATED | 2 | 1 | 4 | 3 | 5 | 16 | 7 |
| 15Q GAIN WILD-TYPE | 76 | 109 | 93 | 45 | 48 | 33 | 70 |
Figure S164. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.049 (Fisher's exact test), Q value = 0.11
Table S165. Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 16P GAIN MUTATED | 16 | 46 | 25 | 44 |
| 16P GAIN WILD-TYPE | 53 | 182 | 54 | 96 |
Figure S165. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0377 (Fisher's exact test), Q value = 0.09
Table S166. Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 16P GAIN MUTATED | 54 | 46 | 31 |
| 16P GAIN WILD-TYPE | 112 | 149 | 120 |
Figure S166. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0106 (Fisher's exact test), Q value = 0.033
Table S167. Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 16P GAIN MUTATED | 32 | 25 | 31 | 9 | 9 | 10 | 15 |
| 16P GAIN WILD-TYPE | 46 | 85 | 66 | 39 | 44 | 39 | 62 |
Figure S167. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0114 (Fisher's exact test), Q value = 0.035
Table S168. Gene #28: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 16P GAIN MUTATED | 40 | 55 | 35 |
| 16P GAIN WILD-TYPE | 149 | 173 | 58 |
Figure S168. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0404 (Fisher's exact test), Q value = 0.095
Table S169. Gene #28: '16p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 16P GAIN MUTATED | 42 | 39 | 29 |
| 16P GAIN WILD-TYPE | 103 | 159 | 62 |
Figure S169. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0391 (Fisher's exact test), Q value = 0.093
Table S170. Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 16Q GAIN MUTATED | 13 | 32 | 19 | 35 |
| 16Q GAIN WILD-TYPE | 56 | 196 | 60 | 105 |
Figure S170. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0305 (Fisher's exact test), Q value = 0.077
Table S171. Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 16Q GAIN MUTATED | 4 | 21 | 11 |
| 16Q GAIN WILD-TYPE | 40 | 52 | 53 |
Figure S171. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0059 (Fisher's exact test), Q value = 0.02
Table S172. Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 16Q GAIN MUTATED | 26 | 44 | 28 |
| 16Q GAIN WILD-TYPE | 163 | 184 | 65 |
Figure S172. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00071
Table S173. Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 17P GAIN MUTATED | 20 | 21 | 19 | 23 |
| 17P GAIN WILD-TYPE | 49 | 207 | 60 | 117 |
Figure S173. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00295 (Fisher's exact test), Q value = 0.011
Table S174. Gene #30: '17p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 17P GAIN MUTATED | 12 | 34 | 25 |
| 17P GAIN WILD-TYPE | 132 | 115 | 137 |
Figure S174. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00549 (Fisher's exact test), Q value = 0.019
Table S175. Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 17P GAIN MUTATED | 19 | 49 | 13 |
| 17P GAIN WILD-TYPE | 170 | 179 | 80 |
Figure S175. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S176. Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 17Q GAIN MUTATED | 30 | 48 | 36 | 77 |
| 17Q GAIN WILD-TYPE | 39 | 180 | 43 | 63 |
Figure S176. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S177. Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 17Q GAIN MUTATED | 31 | 58 | 77 |
| 17Q GAIN WILD-TYPE | 113 | 91 | 85 |
Figure S177. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00206 (Fisher's exact test), Q value = 0.0083
Table S178. Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 17Q GAIN MUTATED | 50 | 91 | 49 |
| 17Q GAIN WILD-TYPE | 116 | 104 | 102 |
Figure S178. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S179. Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 17Q GAIN MUTATED | 29 | 52 | 45 | 5 | 27 | 13 | 19 |
| 17Q GAIN WILD-TYPE | 49 | 58 | 52 | 43 | 26 | 36 | 58 |
Figure S179. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00066
Table S180. Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 17Q GAIN MUTATED | 50 | 106 | 33 |
| 17Q GAIN WILD-TYPE | 139 | 122 | 60 |
Figure S180. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00055
Table S181. Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 17Q GAIN MUTATED | 19 | 86 | 35 | 49 |
| 17Q GAIN WILD-TYPE | 52 | 112 | 106 | 51 |
Figure S181. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0023
Table S182. Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 17Q GAIN MUTATED | 22 | 106 | 34 |
| 17Q GAIN WILD-TYPE | 81 | 142 | 49 |
Figure S182. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S183. Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 18P GAIN MUTATED | 24 | 20 | 13 | 34 |
| 18P GAIN WILD-TYPE | 45 | 208 | 66 | 106 |
Figure S183. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S184. Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 18P GAIN MUTATED | 9 | 39 | 33 |
| 18P GAIN WILD-TYPE | 135 | 110 | 129 |
Figure S184. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00078 (Fisher's exact test), Q value = 0.0037
Table S185. Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18P GAIN MUTATED | 10 | 15 | 26 | 4 | 19 | 6 | 10 |
| 18P GAIN WILD-TYPE | 68 | 95 | 71 | 44 | 34 | 43 | 67 |
Figure S185. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00974 (Fisher's exact test), Q value = 0.031
Table S186. Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 18P GAIN MUTATED | 21 | 50 | 19 |
| 18P GAIN WILD-TYPE | 168 | 178 | 74 |
Figure S186. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00642 (Fisher's exact test), Q value = 0.022
Table S187. Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 18P GAIN MUTATED | 6 | 40 | 18 | 26 |
| 18P GAIN WILD-TYPE | 65 | 158 | 123 | 74 |
Figure S187. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00049
Table S188. Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 18P GAIN MUTATED | 5 | 58 | 16 |
| 18P GAIN WILD-TYPE | 98 | 190 | 67 |
Figure S188. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S189. Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 18Q GAIN MUTATED | 18 | 12 | 18 | 22 |
| 18Q GAIN WILD-TYPE | 51 | 216 | 61 | 118 |
Figure S189. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S190. Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 18Q GAIN MUTATED | 5 | 36 | 20 |
| 18Q GAIN WILD-TYPE | 139 | 113 | 142 |
Figure S190. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0237 (Fisher's exact test), Q value = 0.063
Table S191. Gene #33: '18q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 18Q GAIN MUTATED | 7 | 3 | 11 |
| 18Q GAIN WILD-TYPE | 37 | 70 | 53 |
Figure S191. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0032
Table S192. Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 18Q GAIN MUTATED | 12 | 24 | 33 |
| 18Q GAIN WILD-TYPE | 154 | 171 | 118 |
Figure S192. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S193. Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18Q GAIN MUTATED | 5 | 9 | 18 | 6 | 20 | 5 | 6 |
| 18Q GAIN WILD-TYPE | 73 | 101 | 79 | 42 | 33 | 44 | 71 |
Figure S193. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00668 (Fisher's exact test), Q value = 0.023
Table S194. Gene #33: '18q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 18Q GAIN MUTATED | 15 | 42 | 12 |
| 18Q GAIN WILD-TYPE | 174 | 186 | 81 |
Figure S194. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00188 (Fisher's exact test), Q value = 0.0077
Table S195. Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 18Q GAIN MUTATED | 4 | 30 | 12 | 23 |
| 18Q GAIN WILD-TYPE | 67 | 168 | 129 | 77 |
Figure S195. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0443 (Fisher's exact test), Q value = 0.1
Table S196. Gene #33: '18q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 18Q GAIN MUTATED | 14 | 36 | 9 |
| 18Q GAIN WILD-TYPE | 131 | 162 | 82 |
Figure S196. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00283 (Fisher's exact test), Q value = 0.011
Table S197. Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 18Q GAIN MUTATED | 5 | 44 | 10 |
| 18Q GAIN WILD-TYPE | 98 | 204 | 73 |
Figure S197. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0023
Table S198. Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 19Q GAIN MUTATED | 15 | 22 | 22 | 17 |
| 19Q GAIN WILD-TYPE | 54 | 206 | 57 | 123 |
Figure S198. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00444 (Fisher's exact test), Q value = 0.016
Table S199. Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 19Q GAIN MUTATED | 17 | 36 | 19 |
| 19Q GAIN WILD-TYPE | 127 | 113 | 143 |
Figure S199. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00796 (Fisher's exact test), Q value = 0.026
Table S200. Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 19Q GAIN MUTATED | 14 | 29 | 31 |
| 19Q GAIN WILD-TYPE | 152 | 166 | 120 |
Figure S200. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0264 (Fisher's exact test), Q value = 0.068
Table S201. Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 19Q GAIN MUTATED | 5 | 12 | 17 | 11 | 9 | 12 | 8 |
| 19Q GAIN WILD-TYPE | 73 | 98 | 80 | 37 | 44 | 37 | 69 |
Figure S201. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00141 (Fisher's exact test), Q value = 0.0061
Table S202. Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 19Q GAIN MUTATED | 14 | 51 | 4 |
| 19Q GAIN WILD-TYPE | 89 | 197 | 79 |
Figure S202. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00037
Table S203. Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 20P GAIN MUTATED | 36 | 56 | 33 | 48 |
| 20P GAIN WILD-TYPE | 33 | 172 | 46 | 92 |
Figure S203. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.001
Table S204. Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 20P GAIN MUTATED | 35 | 69 | 47 |
| 20P GAIN WILD-TYPE | 109 | 80 | 115 |
Figure S204. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0032
Table S205. Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 20P GAIN MUTATED | 37 | 71 | 62 |
| 20P GAIN WILD-TYPE | 129 | 124 | 89 |
Figure S205. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S206. Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 20P GAIN MUTATED | 12 | 35 | 52 | 14 | 26 | 16 | 15 |
| 20P GAIN WILD-TYPE | 66 | 75 | 45 | 34 | 27 | 33 | 62 |
Figure S206. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 6e-04
Table S207. Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 20P GAIN MUTATED | 41 | 92 | 38 |
| 20P GAIN WILD-TYPE | 148 | 136 | 55 |
Figure S207. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.001
Table S208. Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 20P GAIN MUTATED | 17 | 75 | 32 | 47 |
| 20P GAIN WILD-TYPE | 54 | 123 | 109 | 53 |
Figure S208. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0465 (Fisher's exact test), Q value = 0.11
Table S209. Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 20P GAIN MUTATED | 37 | 74 | 34 |
| 20P GAIN WILD-TYPE | 108 | 124 | 57 |
Figure S209. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.001
Table S210. Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 20P GAIN MUTATED | 19 | 101 | 25 |
| 20P GAIN WILD-TYPE | 84 | 147 | 58 |
Figure S210. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00383 (Fisher's exact test), Q value = 0.014
Table S211. Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 20Q GAIN MUTATED | 0 | 1 | 2 | 5 |
| 20Q GAIN WILD-TYPE | 5 | 8 | 10 | 1 |
Figure S211. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00918 (Fisher's exact test), Q value = 0.03
Table S212. Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 20Q GAIN MUTATED | 2 | 1 | 5 |
| 20Q GAIN WILD-TYPE | 12 | 10 | 2 |
Figure S212. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S213. Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 20Q GAIN MUTATED | 36 | 54 | 41 | 61 |
| 20Q GAIN WILD-TYPE | 33 | 174 | 38 | 79 |
Figure S213. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S214. Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 20Q GAIN MUTATED | 33 | 77 | 58 |
| 20Q GAIN WILD-TYPE | 111 | 72 | 104 |
Figure S214. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S215. Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 20Q GAIN MUTATED | 38 | 85 | 66 |
| 20Q GAIN WILD-TYPE | 128 | 110 | 85 |
Figure S215. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S216. Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 20Q GAIN MUTATED | 12 | 44 | 58 | 14 | 28 | 18 | 15 |
| 20Q GAIN WILD-TYPE | 66 | 66 | 39 | 34 | 25 | 31 | 62 |
Figure S216. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S217. Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 20Q GAIN MUTATED | 45 | 106 | 37 |
| 20Q GAIN WILD-TYPE | 144 | 122 | 56 |
Figure S217. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S218. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 20Q GAIN MUTATED | 16 | 84 | 37 | 51 |
| 20Q GAIN WILD-TYPE | 55 | 114 | 104 | 49 |
Figure S218. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S219. Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 20Q GAIN MUTATED | 16 | 117 | 28 |
| 20Q GAIN WILD-TYPE | 87 | 131 | 55 |
Figure S219. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00026 (Fisher's exact test), Q value = 0.0014
Table S220. Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 21Q GAIN MUTATED | 8 | 35 | 9 | 44 |
| 21Q GAIN WILD-TYPE | 61 | 193 | 70 | 96 |
Figure S220. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00906 (Fisher's exact test), Q value = 0.029
Table S221. Gene #38: '21q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 21Q GAIN MUTATED | 16 | 2 | 8 | 5 | 7 |
| 21Q GAIN WILD-TYPE | 24 | 31 | 37 | 26 | 25 |
Figure S221. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0012
Table S222. Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 21Q GAIN MUTATED | 41 | 42 | 13 |
| 21Q GAIN WILD-TYPE | 125 | 153 | 138 |
Figure S222. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.0025
Table S223. Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 21Q GAIN MUTATED | 24 | 24 | 25 | 3 | 4 | 7 | 9 |
| 21Q GAIN WILD-TYPE | 54 | 86 | 72 | 45 | 49 | 42 | 68 |
Figure S223. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00059 (Fisher's exact test), Q value = 0.0029
Table S224. Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 22Q GAIN MUTATED | 3 | 18 | 13 | 28 |
| 22Q GAIN WILD-TYPE | 66 | 210 | 66 | 112 |
Figure S224. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0427 (Fisher's exact test), Q value = 0.099
Table S225. Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 22Q GAIN MUTATED | 7 | 12 | 19 | 2 | 4 | 10 | 7 |
| 22Q GAIN WILD-TYPE | 71 | 98 | 78 | 46 | 49 | 39 | 70 |
Figure S225. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00022 (Fisher's exact test), Q value = 0.0012
Table S226. Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| XP GAIN MUTATED | 13 | 10 | 7 | 21 |
| XP GAIN WILD-TYPE | 56 | 218 | 72 | 119 |
Figure S226. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00316 (Fisher's exact test), Q value = 0.012
Table S227. Gene #40: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| XP GAIN MUTATED | 5 | 21 | 19 |
| XP GAIN WILD-TYPE | 139 | 128 | 143 |
Figure S227. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0268 (Fisher's exact test), Q value = 0.069
Table S228. Gene #40: 'xp gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| XP GAIN MUTATED | 6 | 27 | 6 | 11 |
| XP GAIN WILD-TYPE | 65 | 171 | 135 | 89 |
Figure S228. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00014 (Fisher's exact test), Q value = 0.00086
Table S229. Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| XQ GAIN MUTATED | 14 | 22 | 9 | 38 |
| XQ GAIN WILD-TYPE | 55 | 206 | 70 | 102 |
Figure S229. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0165 (Fisher's exact test), Q value = 0.047
Table S230. Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| XQ GAIN MUTATED | 13 | 22 | 26 | 5 | 5 | 4 | 8 |
| XQ GAIN WILD-TYPE | 65 | 88 | 71 | 43 | 48 | 45 | 69 |
Figure S230. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S231. Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 1P LOSS MUTATED | 22 | 35 | 18 | 8 |
| 1P LOSS WILD-TYPE | 47 | 193 | 61 | 132 |
Figure S231. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0482 (Fisher's exact test), Q value = 0.11
Table S232. Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 1P LOSS MUTATED | 15 | 31 | 25 |
| 1P LOSS WILD-TYPE | 129 | 118 | 137 |
Figure S232. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0013
Table S233. Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 1P LOSS MUTATED | 15 | 27 | 39 |
| 1P LOSS WILD-TYPE | 151 | 168 | 112 |
Figure S233. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00037
Table S234. Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 1P LOSS MUTATED | 9 | 16 | 8 | 10 | 21 | 11 | 6 |
| 1P LOSS WILD-TYPE | 69 | 94 | 89 | 38 | 32 | 38 | 71 |
Figure S234. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0104 (Fisher's exact test), Q value = 0.033
Table S235. Gene #43: '1q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 1Q LOSS MUTATED | 0 | 11 | 5 |
| 1Q LOSS WILD-TYPE | 44 | 62 | 59 |
Figure S235. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00066
Table S236. Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 3P LOSS MUTATED | 36 | 69 | 42 | 66 |
| 3P LOSS WILD-TYPE | 33 | 159 | 37 | 74 |
Figure S236. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S237. Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 3P LOSS MUTATED | 40 | 84 | 62 |
| 3P LOSS WILD-TYPE | 104 | 65 | 100 |
Figure S237. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00449 (Fisher's exact test), Q value = 0.016
Table S238. Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 3P LOSS MUTATED | 57 | 75 | 78 |
| 3P LOSS WILD-TYPE | 109 | 120 | 73 |
Figure S238. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S239. Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3P LOSS MUTATED | 28 | 37 | 51 | 19 | 33 | 24 | 18 |
| 3P LOSS WILD-TYPE | 50 | 73 | 46 | 29 | 20 | 25 | 59 |
Figure S239. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0173 (Fisher's exact test), Q value = 0.049
Table S240. Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 3P LOSS MUTATED | 63 | 100 | 46 |
| 3P LOSS WILD-TYPE | 126 | 128 | 47 |
Figure S240. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0159 (Fisher's exact test), Q value = 0.045
Table S241. Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 3P LOSS MUTATED | 28 | 80 | 47 | 54 |
| 3P LOSS WILD-TYPE | 43 | 118 | 94 | 46 |
Figure S241. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0308 (Fisher's exact test), Q value = 0.077
Table S242. Gene #46: '3p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 3P LOSS MUTATED | 33 | 116 | 32 |
| 3P LOSS WILD-TYPE | 70 | 132 | 51 |
Figure S242. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0133 (Fisher's exact test), Q value = 0.04
Table S243. Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 3Q LOSS MUTATED | 29 | 51 | 23 | 43 |
| 3Q LOSS WILD-TYPE | 40 | 177 | 56 | 97 |
Figure S243. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0256 (Fisher's exact test), Q value = 0.067
Table S244. Gene #47: '3q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 3Q LOSS MUTATED | 29 | 50 | 49 |
| 3Q LOSS WILD-TYPE | 115 | 99 | 113 |
Figure S244. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00619 (Fisher's exact test), Q value = 0.021
Table S245. Gene #47: '3q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 3Q LOSS MUTATED | 45 | 42 | 56 |
| 3Q LOSS WILD-TYPE | 121 | 153 | 95 |
Figure S245. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0225 (Fisher's exact test), Q value = 0.06
Table S246. Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 3Q LOSS MUTATED | 24 | 28 | 21 | 18 | 23 | 15 | 14 |
| 3Q LOSS WILD-TYPE | 54 | 82 | 76 | 30 | 30 | 34 | 63 |
Figure S246. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00115 (Fisher's exact test), Q value = 0.0051
Table S247. Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 4P LOSS MUTATED | 22 | 36 | 22 | 44 |
| 4P LOSS WILD-TYPE | 47 | 192 | 57 | 96 |
Figure S247. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0014
Table S248. Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 4P LOSS MUTATED | 24 | 52 | 29 |
| 4P LOSS WILD-TYPE | 120 | 97 | 133 |
Figure S248. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0264 (Fisher's exact test), Q value = 0.068
Table S249. Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 4P LOSS MUTATED | 28 | 50 | 44 |
| 4P LOSS WILD-TYPE | 138 | 145 | 107 |
Figure S249. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S250. Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 4P LOSS MUTATED | 13 | 18 | 40 | 2 | 22 | 14 | 13 |
| 4P LOSS WILD-TYPE | 65 | 92 | 57 | 46 | 31 | 35 | 64 |
Figure S250. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S251. Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 4P LOSS MUTATED | 23 | 76 | 23 |
| 4P LOSS WILD-TYPE | 166 | 152 | 70 |
Figure S251. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S252. Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 4P LOSS MUTATED | 6 | 56 | 23 | 37 |
| 4P LOSS WILD-TYPE | 65 | 142 | 118 | 63 |
Figure S252. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 6e-04
Table S253. Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 4P LOSS MUTATED | 13 | 77 | 12 |
| 4P LOSS WILD-TYPE | 90 | 171 | 71 |
Figure S253. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00096 (Fisher's exact test), Q value = 0.0044
Table S254. Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 4Q LOSS MUTATED | 2 | 2 | 0 | 5 |
| 4Q LOSS WILD-TYPE | 3 | 7 | 12 | 1 |
Figure S254. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00925 (Fisher's exact test), Q value = 0.03
Table S255. Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 4Q LOSS MUTATED | 1 | 3 | 5 |
| 4Q LOSS WILD-TYPE | 13 | 8 | 2 |
Figure S255. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00055
Table S256. Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 4Q LOSS MUTATED | 29 | 40 | 27 | 45 |
| 4Q LOSS WILD-TYPE | 40 | 188 | 52 | 95 |
Figure S256. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S257. Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 4Q LOSS MUTATED | 25 | 64 | 31 |
| 4Q LOSS WILD-TYPE | 119 | 85 | 131 |
Figure S257. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S258. Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 4Q LOSS MUTATED | 26 | 55 | 58 |
| 4Q LOSS WILD-TYPE | 140 | 140 | 93 |
Figure S258. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S259. Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 4Q LOSS MUTATED | 11 | 18 | 43 | 5 | 29 | 20 | 13 |
| 4Q LOSS WILD-TYPE | 67 | 92 | 54 | 43 | 24 | 29 | 64 |
Figure S259. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S260. Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 4Q LOSS MUTATED | 27 | 86 | 26 |
| 4Q LOSS WILD-TYPE | 162 | 142 | 67 |
Figure S260. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S261. Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 4Q LOSS MUTATED | 8 | 63 | 22 | 46 |
| 4Q LOSS WILD-TYPE | 63 | 135 | 119 | 54 |
Figure S261. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.00095
Table S262. Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 4Q LOSS MUTATED | 15 | 85 | 16 |
| 4Q LOSS WILD-TYPE | 88 | 163 | 67 |
Figure S262. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0106 (Fisher's exact test), Q value = 0.033
Table S263. Gene #50: '5p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 5P LOSS MUTATED | 8 | 21 | 22 |
| 5P LOSS WILD-TYPE | 158 | 174 | 129 |
Figure S263. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0201 (Fisher's exact test), Q value = 0.055
Table S264. Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 5P LOSS MUTATED | 3 | 19 | 11 | 18 |
| 5P LOSS WILD-TYPE | 68 | 179 | 130 | 82 |
Figure S264. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0212 (Fisher's exact test), Q value = 0.057
Table S265. Gene #50: '5p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 5P LOSS MUTATED | 4 | 28 | 3 |
| 5P LOSS WILD-TYPE | 99 | 220 | 80 |
Figure S265. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S266. Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 5Q LOSS MUTATED | 27 | 41 | 35 | 50 |
| 5Q LOSS WILD-TYPE | 42 | 187 | 44 | 90 |
Figure S266. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S267. Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 5Q LOSS MUTATED | 23 | 57 | 53 |
| 5Q LOSS WILD-TYPE | 121 | 92 | 109 |
Figure S267. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.054
Table S268. Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 5Q LOSS MUTATED | 7 | 29 | 17 |
| 5Q LOSS WILD-TYPE | 37 | 44 | 47 |
Figure S268. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S269. Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 5Q LOSS MUTATED | 28 | 66 | 57 |
| 5Q LOSS WILD-TYPE | 138 | 129 | 94 |
Figure S269. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S270. Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 5Q LOSS MUTATED | 7 | 41 | 36 | 8 | 22 | 18 | 19 |
| 5Q LOSS WILD-TYPE | 71 | 69 | 61 | 40 | 31 | 31 | 58 |
Figure S270. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S271. Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 5Q LOSS MUTATED | 33 | 91 | 26 |
| 5Q LOSS WILD-TYPE | 156 | 137 | 67 |
Figure S271. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S272. Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 5Q LOSS MUTATED | 10 | 68 | 25 | 47 |
| 5Q LOSS WILD-TYPE | 61 | 130 | 116 | 53 |
Figure S272. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S273. Gene #51: '5q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 5Q LOSS MUTATED | 13 | 94 | 19 |
| 5Q LOSS WILD-TYPE | 90 | 154 | 64 |
Figure S273. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0311 (Fisher's exact test), Q value = 0.077
Table S274. Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 6P LOSS MUTATED | 1 | 5 | 1 | 0 |
| 6P LOSS WILD-TYPE | 4 | 4 | 11 | 6 |
Figure S274. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00759 (Fisher's exact test), Q value = 0.025
Table S275. Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 14 | 11 | 7 |
| 6P LOSS MUTATED | 1 | 6 | 0 |
| 6P LOSS WILD-TYPE | 13 | 5 | 7 |
Figure S275. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.033 (Fisher's exact test), Q value = 0.081
Table S276. Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 6P LOSS MUTATED | 27 | 24 | 45 |
| 6P LOSS WILD-TYPE | 117 | 125 | 117 |
Figure S276. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00403 (Fisher's exact test), Q value = 0.015
Table S277. Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 6P LOSS MUTATED | 15 | 52 | 29 | 9 |
| 6P LOSS WILD-TYPE | 56 | 146 | 112 | 91 |
Figure S277. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0027 (Fisher's exact test), Q value = 0.01
Table S278. Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 6Q LOSS MUTATED | 42 | 81 | 36 | 58 |
| 6Q LOSS WILD-TYPE | 27 | 147 | 43 | 82 |
Figure S278. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S279. Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 6Q LOSS MUTATED | 45 | 57 | 92 |
| 6Q LOSS WILD-TYPE | 99 | 92 | 70 |
Figure S279. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00089 (Fisher's exact test), Q value = 0.0041
Table S280. Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 6Q LOSS MUTATED | 29 | 56 | 28 | 28 | 29 | 18 | 26 |
| 6Q LOSS WILD-TYPE | 49 | 54 | 69 | 20 | 24 | 31 | 51 |
Figure S280. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00096 (Fisher's exact test), Q value = 0.0044
Table S281. Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 6Q LOSS MUTATED | 32 | 102 | 52 | 29 |
| 6Q LOSS WILD-TYPE | 39 | 96 | 89 | 71 |
Figure S281. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-04 (Fisher's exact test), Q value = 0.0016
Table S282. Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 7P LOSS MUTATED | 10 | 16 | 11 | 2 |
| 7P LOSS WILD-TYPE | 59 | 212 | 68 | 138 |
Figure S282. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0464 (Fisher's exact test), Q value = 0.11
Table S283. Gene #54: '7p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 7P LOSS MUTATED | 8 | 12 | 18 |
| 7P LOSS WILD-TYPE | 158 | 183 | 133 |
Figure S283. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0133 (Fisher's exact test), Q value = 0.04
Table S284. Gene #54: '7p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 7P LOSS MUTATED | 2 | 6 | 7 | 7 | 8 | 6 | 2 |
| 7P LOSS WILD-TYPE | 76 | 104 | 90 | 41 | 45 | 43 | 75 |
Figure S284. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00644 (Fisher's exact test), Q value = 0.022
Table S285. Gene #54: '7p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 7P LOSS MUTATED | 16 | 10 | 1 |
| 7P LOSS WILD-TYPE | 129 | 188 | 90 |
Figure S285. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0238 (Fisher's exact test), Q value = 0.063
Table S286. Gene #55: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 7Q LOSS MUTATED | 11 | 18 | 11 | 7 |
| 7Q LOSS WILD-TYPE | 58 | 210 | 68 | 133 |
Figure S286. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0132 (Fisher's exact test), Q value = 0.04
Table S287. Gene #56: '8p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 5 | 9 | 12 | 6 |
| 8P LOSS MUTATED | 4 | 7 | 2 | 2 |
| 8P LOSS WILD-TYPE | 1 | 2 | 10 | 4 |
Figure S287. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S288. Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 8P LOSS MUTATED | 21 | 60 | 38 | 84 |
| 8P LOSS WILD-TYPE | 48 | 168 | 41 | 56 |
Figure S288. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0477 (Fisher's exact test), Q value = 0.11
Table S289. Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 8P LOSS MUTATED | 47 | 57 | 75 |
| 8P LOSS WILD-TYPE | 97 | 92 | 87 |
Figure S289. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0055 (Fisher's exact test), Q value = 0.019
Table S290. Gene #56: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 8P LOSS MUTATED | 16 | 7 | 27 | 9 | 10 |
| 8P LOSS WILD-TYPE | 24 | 26 | 18 | 22 | 22 |
Figure S290. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S291. Gene #56: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 8P LOSS MUTATED | 52 | 106 | 43 |
| 8P LOSS WILD-TYPE | 114 | 89 | 108 |
Figure S291. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00049
Table S292. Gene #56: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 8P LOSS MUTATED | 30 | 56 | 51 | 8 | 16 | 15 | 25 |
| 8P LOSS WILD-TYPE | 48 | 54 | 46 | 40 | 37 | 34 | 52 |
Figure S292. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0104 (Fisher's exact test), Q value = 0.033
Table S293. Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 8P LOSS MUTATED | 59 | 104 | 38 |
| 8P LOSS WILD-TYPE | 130 | 124 | 55 |
Figure S293. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.041 (Fisher's exact test), Q value = 0.097
Table S294. Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 8P LOSS MUTATED | 23 | 89 | 45 | 44 |
| 8P LOSS WILD-TYPE | 48 | 109 | 96 | 56 |
Figure S294. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0219 (Fisher's exact test), Q value = 0.059
Table S295. Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 8P LOSS MUTATED | 44 | 86 | 41 |
| 8P LOSS WILD-TYPE | 101 | 112 | 50 |
Figure S295. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0119 (Fisher's exact test), Q value = 0.036
Table S296. Gene #56: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 8P LOSS MUTATED | 28 | 109 | 34 |
| 8P LOSS WILD-TYPE | 75 | 139 | 49 |
Figure S296. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0194 (Fisher's exact test), Q value = 0.054
Table S297. Gene #57: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 8Q LOSS MUTATED | 3 | 26 | 6 | 25 |
| 8Q LOSS WILD-TYPE | 66 | 202 | 73 | 115 |
Figure S297. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0149 (Fisher's exact test), Q value = 0.043
Table S298. Gene #57: '8q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 8Q LOSS MUTATED | 19 | 31 | 9 |
| 8Q LOSS WILD-TYPE | 147 | 164 | 142 |
Figure S298. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S299. Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 9P LOSS MUTATED | 33 | 94 | 61 | 82 |
| 9P LOSS WILD-TYPE | 36 | 134 | 18 | 58 |
Figure S299. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00196 (Fisher's exact test), Q value = 0.008
Table S300. Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 9P LOSS MUTATED | 62 | 94 | 79 |
| 9P LOSS WILD-TYPE | 82 | 55 | 83 |
Figure S300. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0257 (Fisher's exact test), Q value = 0.067
Table S301. Gene #58: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 9P LOSS MUTATED | 24 | 18 | 28 | 19 | 9 |
| 9P LOSS WILD-TYPE | 16 | 15 | 17 | 12 | 23 |
Figure S301. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 8e-04
Table S302. Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9P LOSS MUTATED | 40 | 51 | 61 | 20 | 25 | 39 | 32 |
| 9P LOSS WILD-TYPE | 38 | 59 | 36 | 28 | 28 | 10 | 45 |
Figure S302. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00632 (Fisher's exact test), Q value = 0.022
Table S303. Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 9P LOSS MUTATED | 89 | 115 | 62 |
| 9P LOSS WILD-TYPE | 100 | 113 | 31 |
Figure S303. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00164 (Fisher's exact test), Q value = 0.0069
Table S304. Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 9P LOSS MUTATED | 32 | 100 | 65 | 69 |
| 9P LOSS WILD-TYPE | 39 | 98 | 76 | 31 |
Figure S304. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S305. Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 9Q LOSS MUTATED | 36 | 84 | 56 | 78 |
| 9Q LOSS WILD-TYPE | 33 | 144 | 23 | 62 |
Figure S305. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00224 (Fisher's exact test), Q value = 0.009
Table S306. Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 9Q LOSS MUTATED | 57 | 88 | 72 |
| 9Q LOSS WILD-TYPE | 87 | 61 | 90 |
Figure S306. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0307 (Fisher's exact test), Q value = 0.077
Table S307. Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 9Q LOSS MUTATED | 22 | 14 | 27 | 15 | 8 |
| 9Q LOSS WILD-TYPE | 18 | 19 | 18 | 16 | 24 |
Figure S307. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00066 (Fisher's exact test), Q value = 0.0032
Table S308. Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 9Q LOSS MUTATED | 37 | 50 | 59 | 14 | 30 | 32 | 30 |
| 9Q LOSS WILD-TYPE | 41 | 60 | 38 | 34 | 23 | 17 | 47 |
Figure S308. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00191 (Fisher's exact test), Q value = 0.0078
Table S309. Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 9Q LOSS MUTATED | 75 | 118 | 57 |
| 9Q LOSS WILD-TYPE | 114 | 110 | 36 |
Figure S309. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00037
Table S310. Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 9Q LOSS MUTATED | 29 | 94 | 57 | 70 |
| 9Q LOSS WILD-TYPE | 42 | 104 | 84 | 30 |
Figure S310. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0126 (Fisher's exact test), Q value = 0.038
Table S311. Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 9Q LOSS MUTATED | 37 | 132 | 40 |
| 9Q LOSS WILD-TYPE | 66 | 116 | 43 |
Figure S311. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00049 (Fisher's exact test), Q value = 0.0024
Table S312. Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 10P LOSS MUTATED | 11 | 39 | 15 | 49 |
| 10P LOSS WILD-TYPE | 58 | 189 | 64 | 91 |
Figure S312. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0128 (Fisher's exact test), Q value = 0.038
Table S313. Gene #60: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 10P LOSS MUTATED | 15 | 2 | 13 | 6 | 5 |
| 10P LOSS WILD-TYPE | 25 | 31 | 32 | 25 | 27 |
Figure S313. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00098 (Fisher's exact test), Q value = 0.0044
Table S314. Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 10P LOSS MUTATED | 34 | 58 | 20 |
| 10P LOSS WILD-TYPE | 132 | 137 | 131 |
Figure S314. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S315. Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10P LOSS MUTATED | 18 | 29 | 38 | 0 | 10 | 3 | 14 |
| 10P LOSS WILD-TYPE | 60 | 81 | 59 | 48 | 43 | 46 | 63 |
Figure S315. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00346 (Fisher's exact test), Q value = 0.013
Table S316. Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 10P LOSS MUTATED | 31 | 48 | 32 |
| 10P LOSS WILD-TYPE | 158 | 180 | 61 |
Figure S316. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0386 (Fisher's exact test), Q value = 0.092
Table S317. Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 10P LOSS MUTATED | 21 | 49 | 23 |
| 10P LOSS WILD-TYPE | 124 | 149 | 68 |
Figure S317. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00076 (Fisher's exact test), Q value = 0.0036
Table S318. Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 10Q LOSS MUTATED | 16 | 44 | 22 | 54 |
| 10Q LOSS WILD-TYPE | 53 | 184 | 57 | 86 |
Figure S318. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0307 (Fisher's exact test), Q value = 0.077
Table S319. Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 10Q LOSS MUTATED | 27 | 48 | 43 |
| 10Q LOSS WILD-TYPE | 117 | 101 | 119 |
Figure S319. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0296 (Fisher's exact test), Q value = 0.075
Table S320. Gene #61: '10q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 10Q LOSS MUTATED | 5 | 24 | 17 |
| 10Q LOSS WILD-TYPE | 39 | 49 | 47 |
Figure S320. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0243 (Fisher's exact test), Q value = 0.064
Table S321. Gene #61: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 10Q LOSS MUTATED | 16 | 4 | 14 | 8 | 4 |
| 10Q LOSS WILD-TYPE | 24 | 29 | 31 | 23 | 28 |
Figure S321. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 6e-04
Table S322. Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 10Q LOSS MUTATED | 36 | 72 | 26 |
| 10Q LOSS WILD-TYPE | 130 | 123 | 125 |
Figure S322. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S323. Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 10Q LOSS MUTATED | 21 | 33 | 49 | 0 | 10 | 8 | 13 |
| 10Q LOSS WILD-TYPE | 57 | 77 | 48 | 48 | 43 | 41 | 64 |
Figure S323. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00557 (Fisher's exact test), Q value = 0.019
Table S324. Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 10Q LOSS MUTATED | 36 | 63 | 34 |
| 10Q LOSS WILD-TYPE | 153 | 165 | 59 |
Figure S324. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0116 (Fisher's exact test), Q value = 0.035
Table S325. Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 10Q LOSS MUTATED | 10 | 56 | 32 | 35 |
| 10Q LOSS WILD-TYPE | 61 | 142 | 109 | 65 |
Figure S325. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0217 (Fisher's exact test), Q value = 0.059
Table S326. Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 10Q LOSS MUTATED | 27 | 63 | 23 |
| 10Q LOSS WILD-TYPE | 118 | 135 | 68 |
Figure S326. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0024 (Fisher's exact test), Q value = 0.0095
Table S327. Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 10Q LOSS MUTATED | 14 | 76 | 23 |
| 10Q LOSS WILD-TYPE | 89 | 172 | 60 |
Figure S327. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.00095
Table S328. Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 11P LOSS MUTATED | 19 | 31 | 24 | 42 |
| 11P LOSS WILD-TYPE | 50 | 197 | 55 | 98 |
Figure S328. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.029 (Fisher's exact test), Q value = 0.074
Table S329. Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 11P LOSS MUTATED | 24 | 44 | 34 |
| 11P LOSS WILD-TYPE | 120 | 105 | 128 |
Figure S329. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00037
Table S330. Gene #62: '11p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 11P LOSS MUTATED | 18 | 57 | 38 |
| 11P LOSS WILD-TYPE | 148 | 138 | 113 |
Figure S330. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00061 (Fisher's exact test), Q value = 0.003
Table S331. Gene #62: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11P LOSS MUTATED | 7 | 31 | 26 | 8 | 13 | 18 | 10 |
| 11P LOSS WILD-TYPE | 71 | 79 | 71 | 40 | 40 | 31 | 67 |
Figure S331. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00141 (Fisher's exact test), Q value = 0.0061
Table S332. Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 11Q LOSS MUTATED | 19 | 25 | 20 | 27 |
| 11Q LOSS WILD-TYPE | 50 | 203 | 59 | 113 |
Figure S332. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0428 (Fisher's exact test), Q value = 0.099
Table S333. Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 11Q LOSS MUTATED | 19 | 36 | 26 |
| 11Q LOSS WILD-TYPE | 125 | 113 | 136 |
Figure S333. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00159 (Fisher's exact test), Q value = 0.0067
Table S334. Gene #63: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 11Q LOSS MUTATED | 15 | 39 | 34 |
| 11Q LOSS WILD-TYPE | 151 | 156 | 117 |
Figure S334. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0199 (Fisher's exact test), Q value = 0.055
Table S335. Gene #63: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 11Q LOSS MUTATED | 6 | 19 | 19 | 7 | 15 | 13 | 9 |
| 11Q LOSS WILD-TYPE | 72 | 91 | 78 | 41 | 38 | 36 | 68 |
Figure S335. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S336. Gene #64: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 12P LOSS MUTATED | 14 | 42 | 7 | 51 |
| 12P LOSS WILD-TYPE | 55 | 186 | 72 | 89 |
Figure S336. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0017
Table S337. Gene #64: '12p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 12P LOSS MUTATED | 47 | 48 | 17 |
| 12P LOSS WILD-TYPE | 119 | 147 | 134 |
Figure S337. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00095
Table S338. Gene #64: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12P LOSS MUTATED | 19 | 25 | 33 | 11 | 3 | 3 | 18 |
| 12P LOSS WILD-TYPE | 59 | 85 | 64 | 37 | 50 | 46 | 59 |
Figure S338. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S339. Gene #65: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 12Q LOSS MUTATED | 9 | 39 | 4 | 50 |
| 12Q LOSS WILD-TYPE | 60 | 189 | 75 | 90 |
Figure S339. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S340. Gene #65: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 12Q LOSS MUTATED | 42 | 48 | 10 |
| 12Q LOSS WILD-TYPE | 124 | 147 | 141 |
Figure S340. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00043
Table S341. Gene #65: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 12Q LOSS MUTATED | 17 | 25 | 27 | 10 | 1 | 2 | 18 |
| 12Q LOSS WILD-TYPE | 61 | 85 | 70 | 38 | 52 | 47 | 59 |
Figure S341. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S342. Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 13Q LOSS MUTATED | 48 | 72 | 39 | 99 |
| 13Q LOSS WILD-TYPE | 21 | 156 | 40 | 41 |
Figure S342. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0423 (Fisher's exact test), Q value = 0.099
Table S343. Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 13Q LOSS MUTATED | 60 | 80 | 89 |
| 13Q LOSS WILD-TYPE | 84 | 69 | 73 |
Figure S343. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00534 (Fisher's exact test), Q value = 0.019
Table S344. Gene #66: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 13Q LOSS MUTATED | 12 | 42 | 26 |
| 13Q LOSS WILD-TYPE | 32 | 31 | 38 |
Figure S344. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0136 (Fisher's exact test), Q value = 0.04
Table S345. Gene #66: '13q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 13Q LOSS MUTATED | 23 | 9 | 26 | 12 | 10 |
| 13Q LOSS WILD-TYPE | 17 | 24 | 19 | 19 | 22 |
Figure S345. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00043 (Fisher's exact test), Q value = 0.0022
Table S346. Gene #66: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 13Q LOSS MUTATED | 63 | 114 | 78 |
| 13Q LOSS WILD-TYPE | 103 | 81 | 73 |
Figure S346. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S347. Gene #66: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 13Q LOSS MUTATED | 34 | 72 | 55 | 11 | 37 | 18 | 28 |
| 13Q LOSS WILD-TYPE | 44 | 38 | 42 | 37 | 16 | 31 | 49 |
Figure S347. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00698 (Fisher's exact test), Q value = 0.023
Table S348. Gene #66: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 13Q LOSS MUTATED | 78 | 122 | 55 |
| 13Q LOSS WILD-TYPE | 111 | 106 | 38 |
Figure S348. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0224 (Fisher's exact test), Q value = 0.06
Table S349. Gene #66: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 13Q LOSS MUTATED | 33 | 113 | 57 | 52 |
| 13Q LOSS WILD-TYPE | 38 | 85 | 84 | 48 |
Figure S349. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00426 (Fisher's exact test), Q value = 0.015
Table S350. Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 13Q LOSS MUTATED | 38 | 139 | 44 |
| 13Q LOSS WILD-TYPE | 65 | 109 | 39 |
Figure S350. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00055
Table S351. Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 14Q LOSS MUTATED | 9 | 38 | 33 | 34 |
| 14Q LOSS WILD-TYPE | 60 | 190 | 46 | 106 |
Figure S351. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00235 (Fisher's exact test), Q value = 0.0094
Table S352. Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 14Q LOSS MUTATED | 11 | 26 | 20 | 10 | 11 | 23 | 12 |
| 14Q LOSS WILD-TYPE | 67 | 84 | 77 | 38 | 42 | 26 | 65 |
Figure S352. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.032 (Fisher's exact test), Q value = 0.079
Table S353. Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 14Q LOSS MUTATED | 36 | 63 | 15 |
| 14Q LOSS WILD-TYPE | 153 | 165 | 78 |
Figure S353. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S354. Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 15Q LOSS MUTATED | 44 | 76 | 30 | 91 |
| 15Q LOSS WILD-TYPE | 25 | 152 | 49 | 49 |
Figure S354. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00246 (Fisher's exact test), Q value = 0.0097
Table S355. Gene #68: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 15Q LOSS MUTATED | 50 | 74 | 87 |
| 15Q LOSS WILD-TYPE | 94 | 75 | 75 |
Figure S355. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0403 (Fisher's exact test), Q value = 0.095
Table S356. Gene #68: '15q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 15Q LOSS MUTATED | 14 | 41 | 29 |
| 15Q LOSS WILD-TYPE | 30 | 32 | 35 |
Figure S356. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00864 (Fisher's exact test), Q value = 0.028
Table S357. Gene #68: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 15Q LOSS MUTATED | 23 | 8 | 27 | 11 | 15 |
| 15Q LOSS WILD-TYPE | 17 | 25 | 18 | 20 | 17 |
Figure S357. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00518 (Fisher's exact test), Q value = 0.018
Table S358. Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 15Q LOSS MUTATED | 68 | 108 | 61 |
| 15Q LOSS WILD-TYPE | 98 | 87 | 90 |
Figure S358. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S359. Gene #68: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 15Q LOSS MUTATED | 34 | 66 | 55 | 8 | 35 | 8 | 31 |
| 15Q LOSS WILD-TYPE | 44 | 44 | 42 | 40 | 18 | 41 | 46 |
Figure S359. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00049
Table S360. Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 15Q LOSS MUTATED | 65 | 121 | 52 |
| 15Q LOSS WILD-TYPE | 124 | 107 | 41 |
Figure S360. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0119 (Fisher's exact test), Q value = 0.036
Table S361. Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 15Q LOSS MUTATED | 25 | 103 | 56 | 54 |
| 15Q LOSS WILD-TYPE | 46 | 95 | 85 | 46 |
Figure S361. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S362. Gene #68: '15q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 15Q LOSS MUTATED | 29 | 131 | 46 |
| 15Q LOSS WILD-TYPE | 74 | 117 | 37 |
Figure S362. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 8e-04 (Fisher's exact test), Q value = 0.0037
Table S363. Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 16P LOSS MUTATED | 24 | 34 | 22 | 38 |
| 16P LOSS WILD-TYPE | 45 | 194 | 57 | 102 |
Figure S363. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00151 (Fisher's exact test), Q value = 0.0065
Table S364. Gene #69: '16p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 16P LOSS MUTATED | 19 | 43 | 44 |
| 16P LOSS WILD-TYPE | 125 | 106 | 118 |
Figure S364. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0136 (Fisher's exact test), Q value = 0.04
Table S365. Gene #69: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 16P LOSS MUTATED | 5 | 11 | 18 | 5 | 5 |
| 16P LOSS WILD-TYPE | 35 | 22 | 27 | 26 | 27 |
Figure S365. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S366. Gene #69: '16p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 16P LOSS MUTATED | 18 | 65 | 35 |
| 16P LOSS WILD-TYPE | 148 | 130 | 116 |
Figure S366. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0014
Table S367. Gene #69: '16p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 16P LOSS MUTATED | 9 | 40 | 27 | 8 | 15 | 10 | 9 |
| 16P LOSS WILD-TYPE | 69 | 70 | 70 | 40 | 38 | 39 | 68 |
Figure S367. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0133 (Fisher's exact test), Q value = 0.04
Table S368. Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 16P LOSS MUTATED | 32 | 66 | 20 |
| 16P LOSS WILD-TYPE | 157 | 162 | 73 |
Figure S368. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0239 (Fisher's exact test), Q value = 0.063
Table S369. Gene #69: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 16P LOSS MUTATED | 13 | 54 | 22 | 29 |
| 16P LOSS WILD-TYPE | 58 | 144 | 119 | 71 |
Figure S369. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00901 (Fisher's exact test), Q value = 0.029
Table S370. Gene #69: '16p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 16P LOSS MUTATED | 14 | 70 | 17 |
| 16P LOSS WILD-TYPE | 89 | 178 | 66 |
Figure S370. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-04 (Fisher's exact test), Q value = 0.0016
Table S371. Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 16Q LOSS MUTATED | 27 | 43 | 26 | 49 |
| 16Q LOSS WILD-TYPE | 42 | 185 | 53 | 91 |
Figure S371. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0014
Table S372. Gene #70: '16q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 16Q LOSS MUTATED | 22 | 50 | 54 |
| 16Q LOSS WILD-TYPE | 122 | 99 | 108 |
Figure S372. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S373. Gene #70: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 16Q LOSS MUTATED | 25 | 78 | 42 |
| 16Q LOSS WILD-TYPE | 141 | 117 | 109 |
Figure S373. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S374. Gene #70: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 16Q LOSS MUTATED | 13 | 51 | 32 | 9 | 17 | 11 | 12 |
| 16Q LOSS WILD-TYPE | 65 | 59 | 65 | 39 | 36 | 38 | 65 |
Figure S374. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0236 (Fisher's exact test), Q value = 0.062
Table S375. Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 16Q LOSS MUTATED | 41 | 77 | 27 |
| 16Q LOSS WILD-TYPE | 148 | 151 | 66 |
Figure S375. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0141 (Fisher's exact test), Q value = 0.041
Table S376. Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 16Q LOSS MUTATED | 19 | 62 | 27 | 37 |
| 16Q LOSS WILD-TYPE | 52 | 136 | 114 | 63 |
Figure S376. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00275 (Fisher's exact test), Q value = 0.011
Table S377. Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 16Q LOSS MUTATED | 17 | 84 | 20 |
| 16Q LOSS WILD-TYPE | 86 | 164 | 63 |
Figure S377. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S378. Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 17P LOSS MUTATED | 28 | 62 | 35 | 91 |
| 17P LOSS WILD-TYPE | 41 | 166 | 44 | 49 |
Figure S378. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00025
Table S379. Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 17P LOSS MUTATED | 41 | 61 | 88 |
| 17P LOSS WILD-TYPE | 103 | 88 | 74 |
Figure S379. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0411 (Fisher's exact test), Q value = 0.097
Table S380. Gene #71: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 17P LOSS MUTATED | 17 | 43 | 26 |
| 17P LOSS WILD-TYPE | 27 | 30 | 38 |
Figure S380. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0124 (Fisher's exact test), Q value = 0.037
Table S381. Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 17P LOSS MUTATED | 22 | 7 | 26 | 14 | 17 |
| 17P LOSS WILD-TYPE | 18 | 26 | 19 | 17 | 15 |
Figure S381. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S382. Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 17P LOSS MUTATED | 56 | 106 | 52 |
| 17P LOSS WILD-TYPE | 110 | 89 | 99 |
Figure S382. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.001
Table S383. Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 17P LOSS MUTATED | 29 | 62 | 46 | 8 | 22 | 20 | 27 |
| 17P LOSS WILD-TYPE | 49 | 48 | 51 | 40 | 31 | 29 | 50 |
Figure S383. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0145 (Fisher's exact test), Q value = 0.042
Table S384. Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 17P LOSS MUTATED | 31 | 115 | 38 |
| 17P LOSS WILD-TYPE | 72 | 133 | 45 |
Figure S384. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00328 (Fisher's exact test), Q value = 0.012
Table S385. Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 17Q LOSS MUTATED | 9 | 13 | 11 | 24 |
| 17Q LOSS WILD-TYPE | 60 | 215 | 68 | 116 |
Figure S385. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.032
Table S386. Gene #72: '17q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 17Q LOSS MUTATED | 5 | 16 | 3 |
| 17Q LOSS WILD-TYPE | 39 | 57 | 61 |
Figure S386. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0468 (Fisher's exact test), Q value = 0.11
Table S387. Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 17Q LOSS MUTATED | 12 | 30 | 15 |
| 17Q LOSS WILD-TYPE | 154 | 165 | 136 |
Figure S387. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S388. Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 18P LOSS MUTATED | 16 | 59 | 34 | 69 |
| 18P LOSS WILD-TYPE | 53 | 169 | 45 | 71 |
Figure S388. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0101 (Fisher's exact test), Q value = 0.032
Table S389. Gene #73: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 18P LOSS MUTATED | 49 | 83 | 44 |
| 18P LOSS WILD-TYPE | 117 | 112 | 107 |
Figure S389. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00113 (Fisher's exact test), Q value = 0.005
Table S390. Gene #73: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18P LOSS MUTATED | 30 | 49 | 35 | 9 | 12 | 23 | 18 |
| 18P LOSS WILD-TYPE | 48 | 61 | 62 | 39 | 41 | 26 | 59 |
Figure S390. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S391. Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 18Q LOSS MUTATED | 17 | 73 | 36 | 86 |
| 18Q LOSS WILD-TYPE | 52 | 155 | 43 | 54 |
Figure S391. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.011 (Fisher's exact test), Q value = 0.034
Table S392. Gene #74: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 18Q LOSS MUTATED | 13 | 42 | 27 |
| 18Q LOSS WILD-TYPE | 31 | 31 | 37 |
Figure S392. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 8e-04
Table S393. Gene #74: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 18Q LOSS MUTATED | 17 | 6 | 32 | 15 | 12 |
| 18Q LOSS WILD-TYPE | 23 | 27 | 13 | 16 | 20 |
Figure S393. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00069 (Fisher's exact test), Q value = 0.0033
Table S394. Gene #74: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 18Q LOSS MUTATED | 62 | 100 | 48 |
| 18Q LOSS WILD-TYPE | 104 | 95 | 103 |
Figure S394. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00095
Table S395. Gene #74: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 18Q LOSS MUTATED | 38 | 55 | 45 | 8 | 13 | 23 | 28 |
| 18Q LOSS WILD-TYPE | 40 | 55 | 52 | 40 | 40 | 26 | 49 |
Figure S395. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S396. Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 19P LOSS MUTATED | 44 | 69 | 60 | 75 |
| 19P LOSS WILD-TYPE | 25 | 159 | 19 | 65 |
Figure S396. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S397. Gene #75: '19p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 19P LOSS MUTATED | 41 | 99 | 73 |
| 19P LOSS WILD-TYPE | 103 | 50 | 89 |
Figure S397. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S398. Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 19P LOSS MUTATED | 48 | 100 | 98 |
| 19P LOSS WILD-TYPE | 118 | 95 | 53 |
Figure S398. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S399. Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 19P LOSS MUTATED | 22 | 47 | 57 | 33 | 35 | 34 | 18 |
| 19P LOSS WILD-TYPE | 56 | 63 | 40 | 15 | 18 | 15 | 59 |
Figure S399. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S400. Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 19P LOSS MUTATED | 66 | 137 | 39 |
| 19P LOSS WILD-TYPE | 123 | 91 | 54 |
Figure S400. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S401. Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 19P LOSS MUTATED | 31 | 98 | 45 | 68 |
| 19P LOSS WILD-TYPE | 40 | 100 | 96 | 32 |
Figure S401. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.035 (Fisher's exact test), Q value = 0.084
Table S402. Gene #75: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 145 | 198 | 91 |
| 19P LOSS MUTATED | 67 | 104 | 33 |
| 19P LOSS WILD-TYPE | 78 | 94 | 58 |
Figure S402. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00299 (Fisher's exact test), Q value = 0.011
Table S403. Gene #75: '19p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 19P LOSS MUTATED | 40 | 134 | 30 |
| 19P LOSS WILD-TYPE | 63 | 114 | 53 |
Figure S403. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S404. Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 19Q LOSS MUTATED | 27 | 41 | 32 | 60 |
| 19Q LOSS WILD-TYPE | 42 | 187 | 47 | 80 |
Figure S404. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S405. Gene #76: '19q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 19Q LOSS MUTATED | 22 | 63 | 52 |
| 19Q LOSS WILD-TYPE | 122 | 86 | 110 |
Figure S405. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00071
Table S406. Gene #76: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 19Q LOSS MUTATED | 31 | 70 | 58 |
| 19Q LOSS WILD-TYPE | 135 | 125 | 93 |
Figure S406. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S407. Gene #76: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 19Q LOSS MUTATED | 15 | 33 | 40 | 18 | 22 | 22 | 9 |
| 19Q LOSS WILD-TYPE | 63 | 77 | 57 | 30 | 31 | 27 | 68 |
Figure S407. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-04 (Fisher's exact test), Q value = 0.0011
Table S408. Gene #76: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 19Q LOSS MUTATED | 39 | 89 | 27 |
| 19Q LOSS WILD-TYPE | 150 | 139 | 66 |
Figure S408. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S409. Gene #76: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 19Q LOSS MUTATED | 19 | 63 | 25 | 48 |
| 19Q LOSS WILD-TYPE | 52 | 135 | 116 | 52 |
Figure S409. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0347 (Fisher's exact test), Q value = 0.084
Table S410. Gene #76: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 19Q LOSS MUTATED | 23 | 87 | 21 |
| 19Q LOSS WILD-TYPE | 80 | 161 | 62 |
Figure S410. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00188 (Fisher's exact test), Q value = 0.0077
Table S411. Gene #77: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 20P LOSS MUTATED | 12 | 35 | 23 | 43 |
| 20P LOSS WILD-TYPE | 57 | 193 | 56 | 97 |
Figure S411. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00959 (Fisher's exact test), Q value = 0.031
Table S412. Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 20P LOSS MUTATED | 25 | 25 | 48 |
| 20P LOSS WILD-TYPE | 119 | 124 | 114 |
Figure S412. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00184 (Fisher's exact test), Q value = 0.0076
Table S413. Gene #77: '20p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 20P LOSS MUTATED | 6 | 27 | 9 |
| 20P LOSS WILD-TYPE | 38 | 46 | 55 |
Figure S413. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0171 (Fisher's exact test), Q value = 0.048
Table S414. Gene #77: '20p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 20P LOSS MUTATED | 15 | 4 | 14 | 6 | 3 |
| 20P LOSS WILD-TYPE | 25 | 29 | 31 | 25 | 29 |
Figure S414. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0012
Table S415. Gene #77: '20p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 20P LOSS MUTATED | 39 | 56 | 17 |
| 20P LOSS WILD-TYPE | 127 | 139 | 134 |
Figure S415. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00148 (Fisher's exact test), Q value = 0.0064
Table S416. Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 20P LOSS MUTATED | 24 | 35 | 14 | 5 | 7 | 14 | 13 |
| 20P LOSS WILD-TYPE | 54 | 75 | 83 | 43 | 46 | 35 | 64 |
Figure S416. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0306 (Fisher's exact test), Q value = 0.077
Table S417. Gene #77: '20p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 20P LOSS MUTATED | 13 | 54 | 23 |
| 20P LOSS WILD-TYPE | 90 | 194 | 60 |
Figure S417. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S418. Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 21Q LOSS MUTATED | 38 | 50 | 45 | 34 |
| 21Q LOSS WILD-TYPE | 31 | 178 | 34 | 106 |
Figure S418. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00173 (Fisher's exact test), Q value = 0.0072
Table S419. Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 21Q LOSS MUTATED | 29 | 58 | 53 |
| 21Q LOSS WILD-TYPE | 115 | 91 | 109 |
Figure S419. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.015 (Fisher's exact test), Q value = 0.043
Table S420. Gene #79: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 44 | 73 | 64 |
| 21Q LOSS MUTATED | 9 | 23 | 30 |
| 21Q LOSS WILD-TYPE | 35 | 50 | 34 |
Figure S420. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0466 (Fisher's exact test), Q value = 0.11
Table S421. Gene #79: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| 21Q LOSS MUTATED | 10 | 13 | 15 | 17 | 7 |
| 21Q LOSS WILD-TYPE | 30 | 20 | 30 | 14 | 25 |
Figure S421. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S422. Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 21Q LOSS MUTATED | 24 | 65 | 75 |
| 21Q LOSS WILD-TYPE | 142 | 130 | 76 |
Figure S422. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S423. Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 21Q LOSS MUTATED | 11 | 30 | 36 | 13 | 34 | 24 | 16 |
| 21Q LOSS WILD-TYPE | 67 | 80 | 61 | 35 | 19 | 25 | 61 |
Figure S423. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S424. Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 21Q LOSS MUTATED | 39 | 97 | 27 |
| 21Q LOSS WILD-TYPE | 150 | 131 | 66 |
Figure S424. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00043
Table S425. Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 21Q LOSS MUTATED | 15 | 66 | 32 | 50 |
| 21Q LOSS WILD-TYPE | 56 | 132 | 109 | 50 |
Figure S425. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00033 (Fisher's exact test), Q value = 0.0017
Table S426. Gene #79: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 21Q LOSS MUTATED | 20 | 97 | 20 |
| 21Q LOSS WILD-TYPE | 83 | 151 | 63 |
Figure S426. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S427. Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| 22Q LOSS MUTATED | 47 | 59 | 39 | 72 |
| 22Q LOSS WILD-TYPE | 22 | 169 | 40 | 68 |
Figure S427. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S428. Gene #80: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| 22Q LOSS MUTATED | 29 | 86 | 78 |
| 22Q LOSS WILD-TYPE | 115 | 63 | 84 |
Figure S428. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S429. Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 166 | 195 | 151 |
| 22Q LOSS MUTATED | 46 | 95 | 73 |
| 22Q LOSS WILD-TYPE | 120 | 100 | 78 |
Figure S429. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 1e-04
Table S430. Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| 22Q LOSS MUTATED | 24 | 56 | 46 | 15 | 34 | 23 | 16 |
| 22Q LOSS WILD-TYPE | 54 | 54 | 51 | 33 | 19 | 26 | 61 |
Figure S430. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.00095
Table S431. Gene #80: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 189 | 228 | 93 |
| 22Q LOSS MUTATED | 58 | 116 | 38 |
| 22Q LOSS WILD-TYPE | 131 | 112 | 55 |
Figure S431. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00018
Table S432. Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| 22Q LOSS MUTATED | 20 | 98 | 40 | 54 |
| 22Q LOSS WILD-TYPE | 51 | 100 | 101 | 46 |
Figure S432. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 8e-04
Table S433. Gene #80: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 103 | 248 | 83 |
| 22Q LOSS MUTATED | 28 | 127 | 31 |
| 22Q LOSS WILD-TYPE | 75 | 121 | 52 |
Figure S433. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00031
Table S434. Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| XP LOSS MUTATED | 14 | 29 | 16 | 46 |
| XP LOSS WILD-TYPE | 55 | 199 | 63 | 94 |
Figure S434. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0379 (Fisher's exact test), Q value = 0.09
Table S435. Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| XP LOSS MUTATED | 19 | 33 | 39 |
| XP LOSS WILD-TYPE | 125 | 116 | 123 |
Figure S435. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0345 (Fisher's exact test), Q value = 0.084
Table S436. Gene #81: 'xp loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 40 | 33 | 45 | 31 | 32 |
| XP LOSS MUTATED | 5 | 1 | 13 | 5 | 6 |
| XP LOSS WILD-TYPE | 35 | 32 | 32 | 26 | 26 |
Figure S436. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00274 (Fisher's exact test), Q value = 0.011
Table S437. Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 78 | 110 | 97 | 48 | 53 | 49 | 77 |
| XP LOSS MUTATED | 19 | 36 | 22 | 6 | 6 | 7 | 9 |
| XP LOSS WILD-TYPE | 59 | 74 | 75 | 42 | 47 | 42 | 68 |
Figure S437. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00356 (Fisher's exact test), Q value = 0.013
Table S438. Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 69 | 228 | 79 | 140 |
| XQ LOSS MUTATED | 10 | 15 | 14 | 24 |
| XQ LOSS WILD-TYPE | 59 | 213 | 65 | 116 |
Figure S438. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00166 (Fisher's exact test), Q value = 0.0069
Table S439. Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 144 | 149 | 162 |
| XQ LOSS MUTATED | 7 | 26 | 23 |
| XQ LOSS WILD-TYPE | 137 | 123 | 139 |
Figure S439. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00357 (Fisher's exact test), Q value = 0.013
Table S440. Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 71 | 198 | 141 | 100 |
| XQ LOSS MUTATED | 11 | 34 | 7 | 11 |
| XQ LOSS WILD-TYPE | 60 | 164 | 134 | 89 |
Figure S440. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
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Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/LUAD-TP/15092515/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/LUAD-TP/15111023/LUAD-TP.transferedmergedcluster.txt
-
Number of patients = 516
-
Number of significantly arm-level cnvs = 82
-
Number of molecular subtypes = 12
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Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.