This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 82 arm-level events and 12 molecular subtypes across 501 patients, 389 significant findings detected with P value < 0.05 and Q value < 0.25.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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4p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q gain cnv correlated to 'CN_CNMF'.
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5p gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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5q gain cnv correlated to 'MRNASEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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6q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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7q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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8q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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9p gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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9q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p gain cnv correlated to 'MIRSEQ_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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10q gain cnv correlated to 'RPPA_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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11p gain cnv correlated to 'RPPA_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'MRNA_CNMF' and 'CN_CNMF'.
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12p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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15q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p gain cnv correlated to 'MIRSEQ_CHIERARCHICAL'.
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16q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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17p gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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20p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'METHLYATION_CNMF'.
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20q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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22q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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xp gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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xq gain cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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1p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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2p loss cnv correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q loss cnv correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3p loss cnv correlated to 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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4p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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5q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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6p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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6q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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7p loss cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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7q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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8p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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8q loss cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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9p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'RPPA_CHIERARCHICAL'.
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11q loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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12p loss cnv correlated to 'MRNA_CNMF' and 'MRNA_CHIERARCHICAL'.
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12q loss cnv correlated to 'RPPA_CNMF'.
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13q loss cnv correlated to 'METHLYATION_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q loss cnv correlated to 'RPPA_CHIERARCHICAL' and 'MIRSEQ_CNMF'.
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16p loss cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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16q loss cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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17q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF'.
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20p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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20q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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21q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q loss cnv correlated to 'MRNA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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xp loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 12 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 389 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 9q gain | 92 (18%) | 409 |
0.0047 (0.0197) |
0.0005 (0.00364) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.0579 (0.139) |
0.0277 (0.0801) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00021 (0.00175) |
6e-05 (0.000621) |
0.00096 (0.0058) |
0.00162 (0.00843) |
| 9q loss | 245 (49%) | 256 |
1e-05 (0.000147) |
1e-05 (0.000147) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.172 (0.293) |
0.0135 (0.0466) |
1e-05 (0.000147) |
1e-05 (0.000147) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00408 (0.018) |
0.0001 (0.000974) |
| 7q gain | 221 (44%) | 280 |
0.00335 (0.0152) |
0.00034 (0.00263) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.904 (0.944) |
0.226 (0.357) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00046 (0.00343) |
0.00017 (0.00153) |
0.00117 (0.00669) |
0.00069 (0.00444) |
| 12p gain | 229 (46%) | 272 |
0.0182 (0.0586) |
0.0328 (0.0911) |
1e-05 (0.000147) |
0.00561 (0.0226) |
0.22 (0.35) |
0.802 (0.871) |
3e-05 (0.000356) |
0.00216 (0.0106) |
0.0295 (0.0836) |
0.00983 (0.0357) |
0.0235 (0.0719) |
0.0015 (0.00807) |
| 17q gain | 158 (32%) | 343 |
0.00156 (0.00825) |
0.00054 (0.0038) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.42 (0.552) |
0.977 (0.988) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00048 (0.00355) |
0.0113 (0.04) |
0.00053 (0.00378) |
3e-05 (0.000356) |
| 1p loss | 152 (30%) | 349 |
4e-05 (0.000452) |
3e-05 (0.000356) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.885 (0.934) |
0.171 (0.292) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00137 (0.00762) |
1e-05 (0.000147) |
0.00081 (0.00508) |
0.00037 (0.00284) |
| 4q loss | 298 (59%) | 203 |
0.00235 (0.0113) |
0.00103 (0.006) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.293 (0.434) |
0.548 (0.666) |
2e-05 (0.00027) |
0.00027 (0.00218) |
0.00286 (0.0133) |
0.0303 (0.0852) |
0.00064 (0.00428) |
4e-05 (0.000452) |
| 10q loss | 229 (46%) | 272 |
0.00093 (0.00568) |
0.00017 (0.00153) |
4e-05 (0.000452) |
1e-05 (0.000147) |
0.0954 (0.199) |
0.0797 (0.175) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00055 (0.00384) |
1e-05 (0.000147) |
0.0149 (0.0502) |
0.00729 (0.0279) |
| 2p gain | 223 (45%) | 278 |
0.104 (0.209) |
0.0244 (0.0735) |
1e-05 (0.000147) |
2e-05 (0.00027) |
0.419 (0.552) |
0.757 (0.837) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00741 (0.0282) |
0.0308 (0.0862) |
0.00297 (0.0137) |
5e-05 (0.000541) |
| 9p gain | 62 (12%) | 439 |
0.088 (0.189) |
0.0213 (0.0668) |
6e-05 (0.000621) |
5e-05 (0.000541) |
0.175 (0.297) |
0.0479 (0.122) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.0137 (0.047) |
0.0496 (0.125) |
0.00098 (0.00583) |
0.0742 (0.167) |
| 4p loss | 315 (63%) | 186 |
0.00132 (0.00738) |
0.00011 (0.00105) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.211 (0.339) |
0.373 (0.514) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00065 (0.00432) |
0.0547 (0.134) |
1e-05 (0.000147) |
1e-05 (0.000147) |
| 9p loss | 310 (62%) | 191 |
0.00717 (0.0276) |
0.00119 (0.00677) |
1e-05 (0.000147) |
0.0237 (0.0722) |
0.206 (0.333) |
0.0769 (0.17) |
1e-05 (0.000147) |
2e-05 (0.00027) |
0.044 (0.113) |
0.00033 (0.00258) |
0.434 (0.564) |
0.028 (0.0805) |
| 14q loss | 166 (33%) | 335 |
0.0001 (0.000974) |
0.00029 (0.00232) |
0.0181 (0.0585) |
0.0925 (0.196) |
0.054 (0.133) |
0.153 (0.269) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.00018 (0.00158) |
1e-05 (0.000147) |
0.00267 (0.0126) |
0.00218 (0.0106) |
| 1q gain | 203 (41%) | 298 |
0.682 (0.785) |
0.549 (0.666) |
1e-05 (0.000147) |
0.00045 (0.00338) |
0.495 (0.618) |
0.455 (0.584) |
0.00378 (0.0169) |
0.00061 (0.00411) |
0.00108 (0.00625) |
0.00435 (0.0189) |
0.0432 (0.112) |
0.0395 (0.104) |
| 7p gain | 243 (49%) | 258 |
0.0603 (0.143) |
0.0124 (0.0432) |
3e-05 (0.000356) |
0.00014 (0.0013) |
0.57 (0.685) |
0.66 (0.768) |
8e-05 (0.000803) |
1e-05 (0.000147) |
0.0007 (0.00447) |
0.00027 (0.00218) |
0.013 (0.045) |
0.083 (0.181) |
| 18p gain | 150 (30%) | 351 |
0.00796 (0.0301) |
0.00114 (0.00656) |
1e-05 (0.000147) |
1e-05 (0.000147) |
0.488 (0.611) |
0.715 (0.804) |
0.00099 (0.00583) |
1e-05 (0.000147) |
0.0165 (0.054) |
0.283 (0.422) |
0.0867 (0.187) |
0.00052 (0.00376) |
| 18q gain | 104 (21%) | 397 |
0.0164 (0.054) |
0.0143 (0.0488) |
1e-05 (0.000147) |
0.00139 (0.00768) |
0.52 (0.641) |
0.338 (0.482) |
0.00076 (0.00479) |
0.00025 (0.00205) |
0.0576 (0.139) |
0.0329 (0.0912) |
0.259 (0.396) |
0.00217 (0.0106) |
| 19p gain | 111 (22%) | 390 |
0.0464 (0.119) |
0.123 (0.234) |
1e-05 (0.000147) |
0.00018 (0.00158) |
0.0229 (0.0706) |
0.0673 (0.156) |
0.00015 (0.00138) |
0.00221 (0.0107) |
0.13 (0.242) |
0.00159 (0.00837) |
0.0689 (0.158) |
0.00539 (0.022) |
| 10p loss | 214 (43%) | 287 |
0.204 (0.33) |
0.218 (0.348) |
4e-05 (0.000452) |
1e-05 (0.000147) |
0.396 (0.534) |
0.159 (0.277) |
3e-05 (0.000356) |
6e-05 (0.000621) |
0.00038 (0.0029) |
1e-05 (0.000147) |
0.0475 (0.121) |
0.00437 (0.0189) |
| 17q loss | 94 (19%) | 407 |
0.0102 (0.0367) |
0.00498 (0.0207) |
0.00058 (0.00396) |
0.00161 (0.00843) |
0.662 (0.768) |
0.969 (0.983) |
0.00019 (0.00164) |
1e-05 (0.000147) |
0.0768 (0.17) |
0.00908 (0.0333) |
0.694 (0.794) |
0.0434 (0.112) |
| xp loss | 146 (29%) | 355 |
0.228 (0.357) |
0.508 (0.632) |
3e-05 (0.000356) |
1e-05 (0.000147) |
0.347 (0.491) |
0.479 (0.604) |
0.00254 (0.012) |
0.0192 (0.0614) |
0.0118 (0.0418) |
0.00152 (0.00808) |
0.0005 (0.00364) |
1e-05 (0.000147) |
| 8q gain | 257 (51%) | 244 |
0.0484 (0.123) |
0.0367 (0.0987) |
0.0221 (0.0688) |
0.00631 (0.0248) |
0.265 (0.402) |
0.753 (0.836) |
0.00633 (0.0248) |
0.0003 (0.00238) |
0.0652 (0.153) |
0.00471 (0.0197) |
0.413 (0.548) |
0.459 (0.587) |
| 12q gain | 153 (31%) | 348 |
0.0239 (0.0725) |
0.308 (0.453) |
1e-05 (0.000147) |
0.00633 (0.0248) |
0.534 (0.653) |
0.614 (0.728) |
0.00334 (0.0152) |
0.00097 (0.00582) |
0.118 (0.228) |
0.13 (0.242) |
0.00952 (0.0347) |
8e-05 (0.000803) |
| 17p gain | 68 (14%) | 433 |
0.00406 (0.018) |
0.101 (0.204) |
1e-05 (0.000147) |
0.0018 (0.00918) |
0.839 (0.9) |
0.14 (0.254) |
0.00067 (0.0044) |
0.00095 (0.00577) |
0.0166 (0.054) |
0.0955 (0.199) |
0.0503 (0.127) |
0.00734 (0.028) |
| 17p loss | 291 (58%) | 210 |
0.00468 (0.0197) |
0.172 (0.293) |
6e-05 (0.000621) |
0.0113 (0.0401) |
0.435 (0.565) |
0.00631 (0.0248) |
0.00169 (0.00875) |
0.00128 (0.0072) |
0.0947 (0.199) |
0.00073 (0.00463) |
0.133 (0.243) |
0.0929 (0.196) |
| 21q loss | 265 (53%) | 236 |
0.9 (0.941) |
0.322 (0.465) |
1e-05 (0.000147) |
0.00543 (0.0221) |
0.524 (0.645) |
0.45 (0.579) |
0.0602 (0.143) |
0.0384 (0.102) |
0.0158 (0.0524) |
0.00059 (0.004) |
0.0243 (0.0732) |
0.0126 (0.0437) |
| xq loss | 112 (22%) | 389 |
0.076 (0.17) |
0.364 (0.505) |
1e-05 (0.000147) |
0.00013 (0.00122) |
0.651 (0.762) |
0.815 (0.881) |
0.00808 (0.0304) |
0.981 (0.989) |
0.00842 (0.0314) |
0.0147 (0.0498) |
0.0046 (0.0197) |
2e-05 (0.00027) |
| 2q gain | 140 (28%) | 361 |
0.472 (0.599) |
0.36 (0.501) |
0.00045 (0.00338) |
0.0405 (0.106) |
0.453 (0.581) |
0.647 (0.758) |
0.00146 (0.00794) |
0.0213 (0.0668) |
0.145 (0.259) |
0.27 (0.406) |
0.00239 (0.0114) |
0.0123 (0.0429) |
| 4p gain | 32 (6%) | 469 |
0.562 (0.678) |
0.203 (0.33) |
0.00021 (0.00175) |
0.0809 (0.177) |
0.578 (0.694) |
0.41 (0.547) |
0.0298 (0.0841) |
0.00641 (0.025) |
0.00533 (0.0219) |
0.309 (0.453) |
0.0122 (0.0428) |
0.0153 (0.0512) |
| 15q gain | 105 (21%) | 396 |
0.838 (0.899) |
0.427 (0.559) |
0.00086 (0.00536) |
0.00126 (0.00713) |
0.221 (0.35) |
0.659 (0.767) |
0.0015 (0.00807) |
0.011 (0.0395) |
0.108 (0.215) |
0.0356 (0.0964) |
0.086 (0.186) |
0.00214 (0.0106) |
| 22q gain | 221 (44%) | 280 |
0.00827 (0.0309) |
0.0287 (0.0821) |
0.00453 (0.0196) |
0.034 (0.0933) |
0.966 (0.982) |
0.0675 (0.156) |
0.00056 (0.00388) |
0.00013 (0.00122) |
0.802 (0.871) |
0.109 (0.217) |
0.99 (0.996) |
0.755 (0.837) |
| 5q loss | 291 (58%) | 210 |
0.131 (0.243) |
0.0545 (0.134) |
0.00018 (0.00158) |
0.00239 (0.0114) |
0.267 (0.404) |
0.126 (0.236) |
0.006 (0.0241) |
0.00033 (0.00258) |
0.133 (0.243) |
0.0198 (0.0626) |
0.0141 (0.0483) |
0.0945 (0.199) |
| 6p loss | 112 (22%) | 389 |
0.0349 (0.095) |
0.0144 (0.0488) |
0.00392 (0.0175) |
0.00011 (0.00105) |
0.151 (0.266) |
0.145 (0.259) |
3e-05 (0.000356) |
3e-05 (0.000356) |
0.196 (0.32) |
0.163 (0.282) |
0.178 (0.3) |
0.404 (0.541) |
| 6q loss | 113 (23%) | 388 |
0.00469 (0.0197) |
0.00103 (0.006) |
0.0254 (0.0754) |
0.00277 (0.013) |
0.701 (0.797) |
0.396 (0.534) |
0.00179 (0.00918) |
0.0238 (0.0722) |
0.553 (0.67) |
0.756 (0.837) |
0.116 (0.225) |
0.344 (0.488) |
| xq gain | 83 (17%) | 418 |
0.162 (0.281) |
0.0335 (0.0925) |
1e-05 (0.000147) |
0.00348 (0.0157) |
0.697 (0.796) |
0.605 (0.722) |
0.00693 (0.0267) |
0.00865 (0.0321) |
0.0589 (0.141) |
0.294 (0.434) |
0.365 (0.506) |
0.276 (0.413) |
| 5p loss | 78 (16%) | 423 |
0.825 (0.889) |
0.933 (0.959) |
0.00435 (0.0189) |
0.00422 (0.0185) |
0.431 (0.564) |
0.0336 (0.0925) |
0.229 (0.357) |
0.284 (0.424) |
0.0384 (0.102) |
0.372 (0.513) |
0.0155 (0.0516) |
0.0938 (0.198) |
| 19p loss | 167 (33%) | 334 |
0.0384 (0.102) |
0.0534 (0.132) |
3e-05 (0.000356) |
0.544 (0.664) |
0.891 (0.937) |
0.319 (0.462) |
0.0437 (0.113) |
0.0194 (0.0617) |
0.101 (0.205) |
0.00019 (0.00164) |
0.837 (0.899) |
0.162 (0.281) |
| 20q loss | 46 (9%) | 455 |
0.0551 (0.134) |
0.0752 (0.169) |
0.00203 (0.0102) |
0.0235 (0.0719) |
0.436 (0.566) |
0.427 (0.559) |
2e-05 (0.00027) |
0.00144 (0.00787) |
0.01 (0.0362) |
0.0999 (0.203) |
0.464 (0.591) |
0.266 (0.403) |
| 6q gain | 94 (19%) | 407 |
0.0682 (0.157) |
0.121 (0.232) |
0.00151 (0.00808) |
0.392 (0.533) |
0.876 (0.928) |
0.963 (0.98) |
0.0165 (0.054) |
0.0162 (0.0535) |
0.801 (0.871) |
0.179 (0.301) |
0.462 (0.59) |
0.0395 (0.104) |
| 20p gain | 261 (52%) | 240 |
0.0196 (0.0624) |
0.0221 (0.0688) |
1e-05 (0.000147) |
0.00068 (0.0044) |
0.888 (0.935) |
0.311 (0.454) |
0.228 (0.357) |
0.142 (0.257) |
0.0764 (0.17) |
0.718 (0.806) |
0.636 (0.747) |
0.927 (0.956) |
| 2p loss | 21 (4%) | 480 |
0.13 (0.242) |
0.188 (0.313) |
0.374 (0.515) |
0.103 (0.208) |
0.14 (0.254) |
0.1 (0.203) |
0.451 (0.58) |
0.0292 (0.0832) |
0.00659 (0.0255) |
0.529 (0.649) |
0.0376 (0.101) |
0.00057 (0.00392) |
| 7q loss | 51 (10%) | 450 |
0.161 (0.28) |
0.0899 (0.192) |
0.00285 (0.0133) |
0.124 (0.235) |
0.83 (0.894) |
0.0629 (0.149) |
7e-05 (0.000717) |
2e-05 (0.00027) |
0.107 (0.214) |
0.0336 (0.0925) |
0.809 (0.877) |
0.403 (0.541) |
| 16q loss | 182 (36%) | 319 |
0.777 (0.852) |
0.125 (0.235) |
0.0174 (0.0564) |
0.17 (0.292) |
0.132 (0.243) |
0.851 (0.909) |
0.0525 (0.131) |
0.0543 (0.134) |
0.00022 (0.00182) |
0.394 (0.533) |
0.00215 (0.0106) |
0.00183 (0.00928) |
| 22q loss | 98 (20%) | 403 |
0.00907 (0.0333) |
0.1 (0.203) |
0.17 (0.292) |
0.0664 (0.155) |
0.253 (0.388) |
0.0577 (0.139) |
9e-05 (0.000895) |
1e-05 (0.000147) |
0.788 (0.862) |
0.009 (0.0333) |
0.193 (0.318) |
0.199 (0.324) |
| 6p gain | 109 (22%) | 392 |
0.0552 (0.134) |
0.182 (0.305) |
0.00068 (0.0044) |
0.788 (0.862) |
0.935 (0.96) |
0.19 (0.314) |
0.0018 (0.00918) |
0.00647 (0.0252) |
0.951 (0.972) |
0.338 (0.482) |
0.173 (0.293) |
0.154 (0.27) |
| 8p gain | 129 (26%) | 372 |
0.404 (0.541) |
0.552 (0.67) |
0.406 (0.542) |
0.0992 (0.203) |
0.255 (0.39) |
0.952 (0.972) |
0.0366 (0.0986) |
0.0251 (0.0746) |
0.392 (0.533) |
0.0152 (0.0508) |
0.854 (0.91) |
0.863 (0.917) |
| 14q gain | 129 (26%) | 372 |
0.142 (0.257) |
0.0223 (0.0691) |
0.0403 (0.106) |
0.0976 (0.202) |
0.254 (0.389) |
0.328 (0.471) |
0.184 (0.307) |
0.00482 (0.0201) |
0.0731 (0.165) |
0.167 (0.287) |
0.571 (0.686) |
0.907 (0.945) |
| 19q gain | 159 (32%) | 342 |
0.115 (0.224) |
0.179 (0.301) |
5e-05 (0.000541) |
0.0272 (0.0791) |
0.228 (0.357) |
0.118 (0.228) |
0.0221 (0.0688) |
0.507 (0.631) |
0.943 (0.966) |
0.418 (0.552) |
0.363 (0.505) |
0.146 (0.26) |
| xp gain | 65 (13%) | 436 |
0.215 (0.344) |
0.135 (0.248) |
5e-05 (0.000541) |
0.165 (0.284) |
0.772 (0.849) |
0.227 (0.357) |
0.00467 (0.0197) |
0.193 (0.318) |
0.00809 (0.0304) |
0.202 (0.328) |
0.696 (0.796) |
0.308 (0.453) |
| 1q loss | 60 (12%) | 441 |
0.555 (0.671) |
0.671 (0.776) |
0.00229 (0.011) |
0.0892 (0.191) |
0.959 (0.978) |
0.61 (0.726) |
0.0347 (0.095) |
0.0269 (0.0791) |
0.249 (0.383) |
0.0846 (0.183) |
0.227 (0.357) |
0.529 (0.649) |
| 2q loss | 42 (8%) | 459 |
0.707 (0.797) |
1 (1.00) |
0.274 (0.411) |
0.194 (0.318) |
0.881 (0.931) |
0.143 (0.257) |
0.0649 (0.153) |
0.0256 (0.0758) |
3e-05 (0.000356) |
0.193 (0.318) |
0.124 (0.235) |
0.00142 (0.00781) |
| 3p loss | 309 (62%) | 192 |
0.368 (0.51) |
0.051 (0.128) |
0.13 (0.242) |
0.00209 (0.0104) |
0.931 (0.958) |
0.103 (0.208) |
0.396 (0.534) |
0.384 (0.526) |
0.272 (0.409) |
0.00021 (0.00175) |
0.0311 (0.0867) |
0.112 (0.22) |
| 8p loss | 244 (49%) | 257 |
0.923 (0.954) |
0.959 (0.978) |
0.00533 (0.0219) |
0.00093 (0.00568) |
0.103 (0.208) |
0.441 (0.57) |
0.114 (0.223) |
0.085 (0.184) |
0.391 (0.533) |
0.015 (0.0502) |
0.189 (0.313) |
0.623 (0.735) |
| 11p loss | 171 (34%) | 330 |
0.254 (0.389) |
0.251 (0.387) |
0.00609 (0.0244) |
0.00463 (0.0197) |
0.14 (0.255) |
0.00325 (0.0149) |
0.122 (0.234) |
0.627 (0.739) |
0.0556 (0.135) |
0.584 (0.699) |
0.476 (0.604) |
0.0647 (0.153) |
| 13q loss | 311 (62%) | 190 |
0.617 (0.731) |
0.709 (0.798) |
0.0775 (0.171) |
0.0409 (0.107) |
0.705 (0.797) |
0.369 (0.51) |
0.274 (0.411) |
0.706 (0.797) |
0.0769 (0.17) |
0.108 (0.215) |
0.00067 (0.0044) |
0.0251 (0.0746) |
| 20p loss | 42 (8%) | 459 |
0.143 (0.257) |
0.14 (0.255) |
0.0248 (0.0743) |
0.0032 (0.0147) |
0.112 (0.22) |
0.146 (0.26) |
0.201 (0.327) |
0.0311 (0.0867) |
0.44 (0.569) |
0.0642 (0.152) |
0.962 (0.98) |
0.337 (0.481) |
| 3q gain | 316 (63%) | 185 |
0.599 (0.715) |
0.737 (0.823) |
0.0132 (0.0457) |
0.292 (0.433) |
1 (1.00) |
0.112 (0.22) |
0.308 (0.453) |
0.311 (0.454) |
0.449 (0.579) |
0.0271 (0.0791) |
0.688 (0.791) |
0.187 (0.311) |
| 5p gain | 309 (62%) | 192 |
0.775 (0.852) |
0.853 (0.91) |
0.0297 (0.084) |
0.165 (0.284) |
0.311 (0.454) |
0.228 (0.357) |
0.318 (0.462) |
0.479 (0.604) |
0.232 (0.36) |
0.0544 (0.134) |
0.0404 (0.106) |
0.13 (0.242) |
| 5q gain | 93 (19%) | 408 |
0.235 (0.365) |
0.208 (0.336) |
0.376 (0.517) |
0.177 (0.299) |
0.713 (0.802) |
0.149 (0.263) |
0.316 (0.459) |
0.0184 (0.0589) |
0.52 (0.641) |
0.279 (0.418) |
0.115 (0.225) |
0.0363 (0.0981) |
| 10p gain | 79 (16%) | 422 |
0.322 (0.465) |
0.703 (0.797) |
0.109 (0.217) |
0.0949 (0.199) |
0.0653 (0.153) |
0.0846 (0.183) |
0.0701 (0.16) |
0.0534 (0.132) |
0.0453 (0.116) |
0.00054 (0.0038) |
0.899 (0.941) |
0.182 (0.306) |
| 10q gain | 45 (9%) | 456 |
0.113 (0.221) |
0.141 (0.255) |
0.0516 (0.129) |
0.384 (0.526) |
0.0274 (0.0797) |
0.209 (0.336) |
0.06 (0.143) |
0.0111 (0.0398) |
0.411 (0.547) |
0.132 (0.243) |
0.765 (0.844) |
0.353 (0.495) |
| 11p gain | 74 (15%) | 427 |
0.677 (0.781) |
0.477 (0.604) |
0.0589 (0.141) |
0.433 (0.564) |
0.246 (0.38) |
0.0101 (0.0363) |
0.655 (0.764) |
0.923 (0.954) |
0.131 (0.243) |
0.0747 (0.168) |
0.185 (0.309) |
0.0385 (0.102) |
| 11q gain | 91 (18%) | 410 |
0.018 (0.0582) |
0.212 (0.34) |
0.00087 (0.00538) |
0.545 (0.664) |
0.394 (0.533) |
0.0526 (0.131) |
0.246 (0.381) |
0.065 (0.153) |
0.144 (0.259) |
0.111 (0.22) |
0.646 (0.757) |
0.072 (0.164) |
| 16q gain | 87 (17%) | 414 |
0.918 (0.952) |
0.935 (0.96) |
0.0246 (0.0738) |
0.332 (0.475) |
0.692 (0.793) |
0.438 (0.567) |
0.16 (0.279) |
0.652 (0.762) |
0.213 (0.341) |
0.0271 (0.0791) |
0.418 (0.552) |
0.426 (0.558) |
| 20q gain | 251 (50%) | 250 |
0.674 (0.779) |
0.316 (0.459) |
0.00053 (0.00378) |
0.433 (0.564) |
0.559 (0.675) |
0.583 (0.699) |
0.31 (0.454) |
0.116 (0.226) |
0.0957 (0.199) |
0.0291 (0.083) |
0.843 (0.902) |
0.348 (0.491) |
| 7p loss | 58 (12%) | 443 |
0.394 (0.533) |
1 (1.00) |
0.00021 (0.00175) |
0.483 (0.607) |
0.481 (0.606) |
0.123 (0.234) |
0.399 (0.537) |
0.092 (0.195) |
0.0912 (0.194) |
0.00561 (0.0226) |
0.927 (0.956) |
0.296 (0.437) |
| 8q loss | 48 (10%) | 453 |
0.349 (0.492) |
0.356 (0.498) |
0.394 (0.533) |
0.0349 (0.095) |
0.0713 (0.162) |
0.877 (0.928) |
0.265 (0.402) |
0.0419 (0.109) |
0.0993 (0.203) |
0.123 (0.234) |
0.261 (0.397) |
0.908 (0.945) |
| 11q loss | 141 (28%) | 360 |
0.988 (0.995) |
0.758 (0.837) |
0.0063 (0.0248) |
0.00099 (0.00583) |
0.54 (0.66) |
0.867 (0.92) |
0.124 (0.235) |
0.707 (0.797) |
0.0683 (0.157) |
0.236 (0.366) |
0.42 (0.552) |
0.0954 (0.199) |
| 12p loss | 39 (8%) | 462 |
0.0233 (0.0716) |
0.00512 (0.0212) |
0.261 (0.397) |
0.517 (0.639) |
0.099 (0.203) |
0.885 (0.934) |
0.981 (0.989) |
0.111 (0.22) |
0.186 (0.31) |
0.0832 (0.182) |
0.0676 (0.156) |
0.189 (0.314) |
| 15q loss | 142 (28%) | 359 |
0.72 (0.807) |
0.745 (0.831) |
0.121 (0.232) |
0.128 (0.24) |
0.324 (0.467) |
0.00197 (0.00994) |
0.0898 (0.192) |
0.285 (0.424) |
0.0277 (0.0801) |
0.159 (0.277) |
0.53 (0.65) |
0.411 (0.547) |
| 16p loss | 163 (33%) | 338 |
0.979 (0.989) |
0.705 (0.797) |
0.00356 (0.016) |
0.211 (0.339) |
0.12 (0.231) |
0.269 (0.406) |
0.327 (0.471) |
0.443 (0.571) |
0.201 (0.327) |
0.835 (0.898) |
0.0267 (0.0787) |
0.084 (0.183) |
| 4q gain | 23 (5%) | 478 |
0.741 (0.826) |
0.731 (0.817) |
0.00918 (0.0336) |
0.511 (0.635) |
0.876 (0.928) |
0.172 (0.293) |
0.842 (0.902) |
0.89 (0.937) |
0.0963 (0.2) |
0.353 (0.495) |
0.148 (0.263) |
0.193 (0.318) |
| 16p gain | 86 (17%) | 415 |
0.356 (0.498) |
0.553 (0.67) |
0.116 (0.226) |
0.359 (0.501) |
0.613 (0.728) |
0.781 (0.856) |
0.686 (0.789) |
0.769 (0.847) |
0.482 (0.606) |
0.0207 (0.0653) |
0.476 (0.604) |
0.29 (0.431) |
| 12q loss | 48 (10%) | 453 |
0.364 (0.505) |
0.142 (0.257) |
0.813 (0.88) |
0.673 (0.778) |
0.0282 (0.0808) |
0.753 (0.836) |
0.703 (0.797) |
0.791 (0.864) |
0.806 (0.874) |
0.118 (0.228) |
0.543 (0.663) |
0.148 (0.262) |
| 19q loss | 112 (22%) | 389 |
0.614 (0.728) |
0.511 (0.635) |
0.0414 (0.108) |
0.0994 (0.203) |
0.343 (0.487) |
0.693 (0.794) |
0.821 (0.885) |
0.339 (0.482) |
0.479 (0.604) |
0.12 (0.231) |
0.458 (0.586) |
0.568 (0.684) |
| 1p gain | 89 (18%) | 412 |
0.132 (0.243) |
0.153 (0.269) |
0.748 (0.832) |
0.729 (0.816) |
0.491 (0.615) |
0.916 (0.952) |
0.801 (0.871) |
0.433 (0.564) |
0.352 (0.495) |
0.747 (0.831) |
0.351 (0.494) |
0.328 (0.471) |
| 3p gain | 109 (22%) | 392 |
0.977 (0.988) |
0.852 (0.909) |
0.22 (0.35) |
0.0991 (0.203) |
1 (1.00) |
0.251 (0.387) |
0.313 (0.457) |
0.149 (0.263) |
0.921 (0.954) |
0.689 (0.792) |
0.972 (0.985) |
0.497 (0.62) |
| 13q gain | 39 (8%) | 462 |
0.699 (0.797) |
0.662 (0.768) |
0.799 (0.871) |
1 (1.00) |
0.415 (0.549) |
0.662 (0.768) |
0.513 (0.635) |
0.707 (0.797) |
0.227 (0.357) |
0.591 (0.706) |
0.895 (0.939) |
0.914 (0.951) |
| 21q gain | 57 (11%) | 444 |
0.893 (0.938) |
0.815 (0.881) |
0.967 (0.982) |
0.0664 (0.155) |
0.378 (0.518) |
1 (1.00) |
0.409 (0.547) |
0.776 (0.852) |
0.513 (0.635) |
0.466 (0.593) |
0.221 (0.35) |
0.525 (0.646) |
| 3q loss | 69 (14%) | 432 |
0.945 (0.967) |
0.927 (0.956) |
0.496 (0.619) |
0.898 (0.941) |
0.632 (0.743) |
0.412 (0.547) |
0.905 (0.944) |
0.319 (0.462) |
0.609 (0.725) |
0.239 (0.37) |
0.163 (0.281) |
0.344 (0.488) |
| 18p loss | 140 (28%) | 361 |
0.856 (0.911) |
0.653 (0.762) |
0.0921 (0.195) |
0.0579 (0.139) |
0.627 (0.739) |
0.919 (0.952) |
0.196 (0.32) |
0.0733 (0.166) |
0.416 (0.55) |
0.0777 (0.171) |
0.0684 (0.157) |
0.622 (0.735) |
| 18q loss | 189 (38%) | 312 |
0.223 (0.353) |
0.332 (0.475) |
0.0527 (0.131) |
0.394 (0.533) |
0.704 (0.797) |
0.388 (0.53) |
0.486 (0.61) |
0.146 (0.26) |
0.0726 (0.165) |
0.125 (0.235) |
0.0792 (0.174) |
0.619 (0.732) |
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S1. Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 1Q GAIN MUTATED | 65 | 92 | 46 |
| 1Q GAIN WILD-TYPE | 117 | 74 | 107 |
Figure S1. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0034
Table S2. Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 1Q GAIN MUTATED | 46 | 64 | 31 |
| 1Q GAIN WILD-TYPE | 106 | 58 | 62 |
Figure S2. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00378 (Fisher's exact test), Q value = 0.017
Table S3. Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 1Q GAIN MUTATED | 38 | 80 | 59 | 26 |
| 1Q GAIN WILD-TYPE | 75 | 72 | 95 | 53 |
Figure S3. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00061 (Fisher's exact test), Q value = 0.0041
Table S4. Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 1Q GAIN MUTATED | 54 | 94 | 55 |
| 1Q GAIN WILD-TYPE | 124 | 95 | 76 |
Figure S4. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00108 (Fisher's exact test), Q value = 0.0063
Table S5. Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 1Q GAIN MUTATED | 53 | 57 | 35 | 35 | 9 |
| 1Q GAIN WILD-TYPE | 68 | 77 | 86 | 27 | 28 |
Figure S5. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00435 (Fisher's exact test), Q value = 0.019
Table S6. Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 1Q GAIN MUTATED | 49 | 50 | 66 | 24 |
| 1Q GAIN WILD-TYPE | 40 | 68 | 133 | 45 |
Figure S6. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0432 (Fisher's exact test), Q value = 0.11
Table S7. Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 1Q GAIN MUTATED | 24 | 52 | 50 |
| 1Q GAIN WILD-TYPE | 65 | 77 | 66 |
Figure S7. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0395 (Fisher's exact test), Q value = 0.1
Table S8. Gene #2: '1q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 1Q GAIN MUTATED | 11 | 68 | 47 |
| 1Q GAIN WILD-TYPE | 28 | 83 | 97 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0244 (Fisher's exact test), Q value = 0.074
Table S9. Gene #3: '2p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 2P GAIN MUTATED | 19 | 31 | 15 |
| 2P GAIN WILD-TYPE | 28 | 25 | 36 |
Figure S9. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S10. Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 2P GAIN MUTATED | 53 | 108 | 62 |
| 2P GAIN WILD-TYPE | 129 | 58 | 91 |
Figure S10. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00027
Table S11. Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 2P GAIN MUTATED | 53 | 80 | 36 |
| 2P GAIN WILD-TYPE | 99 | 42 | 57 |
Figure S11. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S12. Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 2P GAIN MUTATED | 36 | 94 | 67 | 24 |
| 2P GAIN WILD-TYPE | 77 | 58 | 87 | 55 |
Figure S12. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S13. Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 2P GAIN MUTATED | 62 | 111 | 48 |
| 2P GAIN WILD-TYPE | 116 | 78 | 83 |
Figure S13. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00741 (Fisher's exact test), Q value = 0.028
Table S14. Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 2P GAIN MUTATED | 52 | 77 | 42 | 27 | 16 |
| 2P GAIN WILD-TYPE | 69 | 57 | 79 | 35 | 21 |
Figure S14. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0308 (Fisher's exact test), Q value = 0.086
Table S15. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 2P GAIN MUTATED | 44 | 50 | 99 | 21 |
| 2P GAIN WILD-TYPE | 45 | 68 | 100 | 48 |
Figure S15. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00297 (Fisher's exact test), Q value = 0.014
Table S16. Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 2P GAIN MUTATED | 28 | 62 | 64 |
| 2P GAIN WILD-TYPE | 61 | 67 | 52 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00054
Table S17. Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 2P GAIN MUTATED | 17 | 90 | 47 |
| 2P GAIN WILD-TYPE | 22 | 61 | 97 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00045 (Fisher's exact test), Q value = 0.0034
Table S18. Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 2Q GAIN MUTATED | 36 | 64 | 40 |
| 2Q GAIN WILD-TYPE | 146 | 102 | 113 |
Figure S18. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0405 (Fisher's exact test), Q value = 0.11
Table S19. Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 2Q GAIN MUTATED | 37 | 46 | 24 |
| 2Q GAIN WILD-TYPE | 115 | 76 | 69 |
Figure S19. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00146 (Fisher's exact test), Q value = 0.0079
Table S20. Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 2Q GAIN MUTATED | 24 | 56 | 46 | 12 |
| 2Q GAIN WILD-TYPE | 89 | 96 | 108 | 67 |
Figure S20. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0213 (Fisher's exact test), Q value = 0.067
Table S21. Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 2Q GAIN MUTATED | 38 | 65 | 35 |
| 2Q GAIN WILD-TYPE | 140 | 124 | 96 |
Figure S21. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00239 (Fisher's exact test), Q value = 0.011
Table S22. Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 2Q GAIN MUTATED | 13 | 44 | 38 |
| 2Q GAIN WILD-TYPE | 76 | 85 | 78 |
Figure S22. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0123 (Fisher's exact test), Q value = 0.043
Table S23. Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 2Q GAIN MUTATED | 7 | 55 | 33 |
| 2Q GAIN WILD-TYPE | 32 | 96 | 111 |
Figure S23. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0132 (Fisher's exact test), Q value = 0.046
Table S24. Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 3Q GAIN MUTATED | 103 | 103 | 110 |
| 3Q GAIN WILD-TYPE | 79 | 63 | 43 |
Figure S24. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0271 (Fisher's exact test), Q value = 0.079
Table S25. Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 3Q GAIN MUTATED | 55 | 75 | 136 | 33 |
| 3Q GAIN WILD-TYPE | 34 | 43 | 63 | 36 |
Figure S25. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0018
Table S26. Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 4P GAIN MUTATED | 9 | 3 | 20 |
| 4P GAIN WILD-TYPE | 173 | 163 | 133 |
Figure S26. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0298 (Fisher's exact test), Q value = 0.084
Table S27. Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 4P GAIN MUTATED | 5 | 4 | 16 | 6 |
| 4P GAIN WILD-TYPE | 108 | 148 | 138 | 73 |
Figure S27. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00641 (Fisher's exact test), Q value = 0.025
Table S28. Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 4P GAIN MUTATED | 15 | 4 | 12 |
| 4P GAIN WILD-TYPE | 163 | 185 | 119 |
Figure S28. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00533 (Fisher's exact test), Q value = 0.022
Table S29. Gene #7: '4p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 4P GAIN MUTATED | 10 | 2 | 12 | 1 | 4 |
| 4P GAIN WILD-TYPE | 111 | 132 | 109 | 61 | 33 |
Figure S29. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0122 (Fisher's exact test), Q value = 0.043
Table S30. Gene #7: '4p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 4P GAIN MUTATED | 8 | 8 | 1 |
| 4P GAIN WILD-TYPE | 81 | 121 | 115 |
Figure S30. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0153 (Fisher's exact test), Q value = 0.051
Table S31. Gene #7: '4p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 4P GAIN MUTATED | 5 | 3 | 9 |
| 4P GAIN WILD-TYPE | 34 | 148 | 135 |
Figure S31. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00918 (Fisher's exact test), Q value = 0.034
Table S32. Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 4Q GAIN MUTATED | 4 | 5 | 14 |
| 4Q GAIN WILD-TYPE | 178 | 161 | 139 |
Figure S32. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0297 (Fisher's exact test), Q value = 0.084
Table S33. Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 5P GAIN MUTATED | 102 | 100 | 107 |
| 5P GAIN WILD-TYPE | 80 | 66 | 46 |
Figure S33. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0404 (Fisher's exact test), Q value = 0.11
Table S34. Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 5P GAIN MUTATED | 57 | 89 | 62 |
| 5P GAIN WILD-TYPE | 32 | 40 | 54 |
Figure S34. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0184 (Fisher's exact test), Q value = 0.059
Table S35. Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 5Q GAIN MUTATED | 44 | 25 | 24 |
| 5Q GAIN WILD-TYPE | 134 | 164 | 107 |
Figure S35. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0363 (Fisher's exact test), Q value = 0.098
Table S36. Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 5Q GAIN MUTATED | 14 | 30 | 24 |
| 5Q GAIN WILD-TYPE | 25 | 121 | 120 |
Figure S36. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00068 (Fisher's exact test), Q value = 0.0044
Table S37. Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 6P GAIN MUTATED | 27 | 33 | 49 |
| 6P GAIN WILD-TYPE | 155 | 133 | 104 |
Figure S37. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0018 (Fisher's exact test), Q value = 0.0092
Table S38. Gene #11: '6p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 6P GAIN MUTATED | 15 | 27 | 49 | 17 |
| 6P GAIN WILD-TYPE | 98 | 125 | 105 | 62 |
Figure S38. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00647 (Fisher's exact test), Q value = 0.025
Table S39. Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6P GAIN MUTATED | 36 | 31 | 41 |
| 6P GAIN WILD-TYPE | 142 | 158 | 90 |
Figure S39. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00151 (Fisher's exact test), Q value = 0.0081
Table S40. Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 6Q GAIN MUTATED | 22 | 30 | 42 |
| 6Q GAIN WILD-TYPE | 160 | 136 | 111 |
Figure S40. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0165 (Fisher's exact test), Q value = 0.054
Table S41. Gene #12: '6q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 6Q GAIN MUTATED | 17 | 21 | 42 | 14 |
| 6Q GAIN WILD-TYPE | 96 | 131 | 112 | 65 |
Figure S41. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.053
Table S42. Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6Q GAIN MUTATED | 35 | 25 | 34 |
| 6Q GAIN WILD-TYPE | 143 | 164 | 97 |
Figure S42. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0395 (Fisher's exact test), Q value = 0.1
Table S43. Gene #12: '6q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 6Q GAIN MUTATED | 9 | 37 | 19 |
| 6Q GAIN WILD-TYPE | 30 | 114 | 125 |
Figure S43. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0124 (Fisher's exact test), Q value = 0.043
Table S44. Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 7P GAIN MUTATED | 25 | 38 | 20 |
| 7P GAIN WILD-TYPE | 22 | 18 | 31 |
Figure S44. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S45. Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 7P GAIN MUTATED | 73 | 105 | 65 |
| 7P GAIN WILD-TYPE | 109 | 61 | 88 |
Figure S45. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.0013
Table S46. Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 7P GAIN MUTATED | 55 | 75 | 43 |
| 7P GAIN WILD-TYPE | 97 | 47 | 50 |
Figure S46. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 8e-04
Table S47. Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 7P GAIN MUTATED | 50 | 96 | 68 | 27 |
| 7P GAIN WILD-TYPE | 63 | 56 | 86 | 52 |
Figure S47. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S48. Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 7P GAIN MUTATED | 68 | 121 | 52 |
| 7P GAIN WILD-TYPE | 110 | 68 | 79 |
Figure S48. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 7e-04 (Fisher's exact test), Q value = 0.0045
Table S49. Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 7P GAIN MUTATED | 66 | 81 | 42 | 31 | 15 |
| 7P GAIN WILD-TYPE | 55 | 53 | 79 | 31 | 22 |
Figure S49. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0022
Table S50. Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7P GAIN MUTATED | 61 | 60 | 85 | 29 |
| 7P GAIN WILD-TYPE | 28 | 58 | 114 | 40 |
Figure S50. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.013 (Fisher's exact test), Q value = 0.045
Table S51. Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 7P GAIN MUTATED | 36 | 53 | 67 |
| 7P GAIN WILD-TYPE | 53 | 76 | 49 |
Figure S51. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00335 (Fisher's exact test), Q value = 0.015
Table S52. Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 7Q GAIN MUTATED | 21 | 35 | 9 | 11 |
| 7Q GAIN WILD-TYPE | 21 | 17 | 23 | 17 |
Figure S52. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0026
Table S53. Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 7Q GAIN MUTATED | 23 | 38 | 15 |
| 7Q GAIN WILD-TYPE | 24 | 18 | 36 |
Figure S53. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S54. Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 7Q GAIN MUTATED | 52 | 109 | 60 |
| 7Q GAIN WILD-TYPE | 130 | 57 | 93 |
Figure S54. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S55. Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 7Q GAIN MUTATED | 43 | 75 | 37 |
| 7Q GAIN WILD-TYPE | 109 | 47 | 56 |
Figure S55. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S56. Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 7Q GAIN MUTATED | 43 | 100 | 48 | 28 |
| 7Q GAIN WILD-TYPE | 70 | 52 | 106 | 51 |
Figure S56. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S57. Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 7Q GAIN MUTATED | 56 | 123 | 40 |
| 7Q GAIN WILD-TYPE | 122 | 66 | 91 |
Figure S57. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0034
Table S58. Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 7Q GAIN MUTATED | 59 | 73 | 37 | 33 | 12 |
| 7Q GAIN WILD-TYPE | 62 | 61 | 84 | 29 | 25 |
Figure S58. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0015
Table S59. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7Q GAIN MUTATED | 59 | 48 | 81 | 26 |
| 7Q GAIN WILD-TYPE | 30 | 70 | 118 | 43 |
Figure S59. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00117 (Fisher's exact test), Q value = 0.0067
Table S60. Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 7Q GAIN MUTATED | 26 | 51 | 63 |
| 7Q GAIN WILD-TYPE | 63 | 78 | 53 |
Figure S60. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0044
Table S61. Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 7Q GAIN MUTATED | 9 | 79 | 52 |
| 7Q GAIN WILD-TYPE | 30 | 72 | 92 |
Figure S61. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0366 (Fisher's exact test), Q value = 0.099
Table S62. Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 8P GAIN MUTATED | 27 | 28 | 49 | 24 |
| 8P GAIN WILD-TYPE | 86 | 124 | 105 | 55 |
Figure S62. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0251 (Fisher's exact test), Q value = 0.075
Table S63. Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 8P GAIN MUTATED | 55 | 36 | 37 |
| 8P GAIN WILD-TYPE | 123 | 153 | 94 |
Figure S63. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0152 (Fisher's exact test), Q value = 0.051
Table S64. Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 8P GAIN MUTATED | 16 | 22 | 63 | 21 |
| 8P GAIN WILD-TYPE | 73 | 96 | 136 | 48 |
Figure S64. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0484 (Fisher's exact test), Q value = 0.12
Table S65. Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 8Q GAIN MUTATED | 26 | 18 | 16 | 16 |
| 8Q GAIN WILD-TYPE | 16 | 34 | 16 | 12 |
Figure S65. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0367 (Fisher's exact test), Q value = 0.099
Table S66. Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 8Q GAIN MUTATED | 27 | 20 | 29 |
| 8Q GAIN WILD-TYPE | 20 | 36 | 22 |
Figure S66. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0221 (Fisher's exact test), Q value = 0.069
Table S67. Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 8Q GAIN MUTATED | 93 | 73 | 91 |
| 8Q GAIN WILD-TYPE | 89 | 93 | 62 |
Figure S67. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00631 (Fisher's exact test), Q value = 0.025
Table S68. Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 8Q GAIN MUTATED | 86 | 49 | 55 |
| 8Q GAIN WILD-TYPE | 66 | 73 | 38 |
Figure S68. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00633 (Fisher's exact test), Q value = 0.025
Table S69. Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 8Q GAIN MUTATED | 61 | 61 | 92 | 41 |
| 8Q GAIN WILD-TYPE | 52 | 91 | 62 | 38 |
Figure S69. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0024
Table S70. Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 8Q GAIN MUTATED | 106 | 75 | 74 |
| 8Q GAIN WILD-TYPE | 72 | 114 | 57 |
Figure S70. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00471 (Fisher's exact test), Q value = 0.02
Table S71. Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 8Q GAIN MUTATED | 33 | 53 | 115 | 39 |
| 8Q GAIN WILD-TYPE | 56 | 65 | 84 | 30 |
Figure S71. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0213 (Fisher's exact test), Q value = 0.067
Table S72. Gene #17: '9p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9P GAIN MUTATED | 1 | 9 | 9 |
| 9P GAIN WILD-TYPE | 46 | 47 | 42 |
Figure S72. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00062
Table S73. Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 9P GAIN MUTATED | 21 | 34 | 7 |
| 9P GAIN WILD-TYPE | 161 | 132 | 146 |
Figure S73. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00054
Table S74. Gene #17: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 9P GAIN MUTATED | 11 | 30 | 7 |
| 9P GAIN WILD-TYPE | 141 | 92 | 86 |
Figure S74. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0479 (Fisher's exact test), Q value = 0.12
Table S75. Gene #17: '9p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 9P GAIN MUTATED | 10 | 1 | 3 | 4 |
| 9P GAIN WILD-TYPE | 44 | 40 | 49 | 43 |
Figure S75. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S76. Gene #17: '9p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 9P GAIN MUTATED | 3 | 36 | 15 | 8 |
| 9P GAIN WILD-TYPE | 110 | 116 | 139 | 71 |
Figure S76. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S77. Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9P GAIN MUTATED | 6 | 39 | 17 |
| 9P GAIN WILD-TYPE | 172 | 150 | 114 |
Figure S77. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0137 (Fisher's exact test), Q value = 0.047
Table S78. Gene #17: '9p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 9P GAIN MUTATED | 17 | 22 | 8 | 12 | 1 |
| 9P GAIN WILD-TYPE | 104 | 112 | 113 | 50 | 36 |
Figure S78. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0496 (Fisher's exact test), Q value = 0.13
Table S79. Gene #17: '9p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9P GAIN MUTATED | 16 | 19 | 16 | 9 |
| 9P GAIN WILD-TYPE | 73 | 99 | 183 | 60 |
Figure S79. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00098 (Fisher's exact test), Q value = 0.0058
Table S80. Gene #17: '9p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 9P GAIN MUTATED | 2 | 18 | 20 |
| 9P GAIN WILD-TYPE | 87 | 111 | 96 |
Figure S80. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0047 (Fisher's exact test), Q value = 0.02
Table S81. Gene #18: '9q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 9Q GAIN MUTATED | 2 | 17 | 5 | 7 |
| 9Q GAIN WILD-TYPE | 40 | 35 | 27 | 21 |
Figure S81. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 5e-04 (Fisher's exact test), Q value = 0.0036
Table S82. Gene #18: '9q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9Q GAIN MUTATED | 2 | 19 | 10 |
| 9Q GAIN WILD-TYPE | 45 | 37 | 41 |
Figure S82. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S83. Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 9Q GAIN MUTATED | 23 | 61 | 8 |
| 9Q GAIN WILD-TYPE | 159 | 105 | 145 |
Figure S83. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S84. Gene #18: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 9Q GAIN MUTATED | 12 | 46 | 9 |
| 9Q GAIN WILD-TYPE | 140 | 76 | 84 |
Figure S84. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0277 (Fisher's exact test), Q value = 0.08
Table S85. Gene #18: '9q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 9Q GAIN MUTATED | 14 | 5 | 3 | 9 |
| 9Q GAIN WILD-TYPE | 40 | 36 | 49 | 38 |
Figure S85. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S86. Gene #18: '9q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 9Q GAIN MUTATED | 5 | 60 | 21 | 6 |
| 9Q GAIN WILD-TYPE | 108 | 92 | 133 | 73 |
Figure S86. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S87. Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9Q GAIN MUTATED | 6 | 65 | 21 |
| 9Q GAIN WILD-TYPE | 172 | 124 | 110 |
Figure S87. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0018
Table S88. Gene #18: '9q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 9Q GAIN MUTATED | 24 | 31 | 9 | 20 | 4 |
| 9Q GAIN WILD-TYPE | 97 | 103 | 112 | 42 | 33 |
Figure S88. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00062
Table S89. Gene #18: '9q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9Q GAIN MUTATED | 30 | 26 | 24 | 8 |
| 9Q GAIN WILD-TYPE | 59 | 92 | 175 | 61 |
Figure S89. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00096 (Fisher's exact test), Q value = 0.0058
Table S90. Gene #18: '9q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 9Q GAIN MUTATED | 5 | 26 | 27 |
| 9Q GAIN WILD-TYPE | 84 | 103 | 89 |
Figure S90. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00162 (Fisher's exact test), Q value = 0.0084
Table S91. Gene #18: '9q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 9Q GAIN MUTATED | 2 | 38 | 18 |
| 9Q GAIN WILD-TYPE | 37 | 113 | 126 |
Figure S91. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0453 (Fisher's exact test), Q value = 0.12
Table S92. Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 10P GAIN MUTATED | 17 | 28 | 21 | 3 | 5 |
| 10P GAIN WILD-TYPE | 104 | 106 | 100 | 59 | 32 |
Figure S92. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00054 (Fisher's exact test), Q value = 0.0038
Table S93. Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 10P GAIN MUTATED | 3 | 18 | 42 | 11 |
| 10P GAIN WILD-TYPE | 86 | 100 | 157 | 58 |
Figure S93. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0274 (Fisher's exact test), Q value = 0.08
Table S94. Gene #20: '10q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 60 | 73 | 61 |
| 10Q GAIN MUTATED | 5 | 14 | 3 |
| 10Q GAIN WILD-TYPE | 55 | 59 | 58 |
Figure S94. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0111 (Fisher's exact test), Q value = 0.04
Table S95. Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 10Q GAIN MUTATED | 16 | 9 | 19 |
| 10Q GAIN WILD-TYPE | 162 | 180 | 112 |
Figure S95. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0101 (Fisher's exact test), Q value = 0.036
Table S96. Gene #21: '11p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 11P GAIN MUTATED | 9 | 2 | 8 | 15 |
| 11P GAIN WILD-TYPE | 45 | 39 | 44 | 32 |
Figure S96. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0385 (Fisher's exact test), Q value = 0.1
Table S97. Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 11P GAIN MUTATED | 4 | 30 | 14 |
| 11P GAIN WILD-TYPE | 35 | 121 | 130 |
Figure S97. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.018 (Fisher's exact test), Q value = 0.058
Table S98. Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 11Q GAIN MUTATED | 12 | 7 | 2 | 9 |
| 11Q GAIN WILD-TYPE | 30 | 45 | 30 | 19 |
Figure S98. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00087 (Fisher's exact test), Q value = 0.0054
Table S99. Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 11Q GAIN MUTATED | 20 | 30 | 41 |
| 11Q GAIN WILD-TYPE | 162 | 136 | 112 |
Figure S99. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0182 (Fisher's exact test), Q value = 0.059
Table S100. Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 12P GAIN MUTATED | 11 | 30 | 13 | 14 |
| 12P GAIN WILD-TYPE | 31 | 22 | 19 | 14 |
Figure S100. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0328 (Fisher's exact test), Q value = 0.091
Table S101. Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 12P GAIN MUTATED | 15 | 32 | 21 |
| 12P GAIN WILD-TYPE | 32 | 24 | 30 |
Figure S101. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S102. Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 12P GAIN MUTATED | 49 | 100 | 80 |
| 12P GAIN WILD-TYPE | 133 | 66 | 73 |
Figure S102. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00561 (Fisher's exact test), Q value = 0.023
Table S103. Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 12P GAIN MUTATED | 57 | 67 | 50 |
| 12P GAIN WILD-TYPE | 95 | 55 | 43 |
Figure S103. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S104. Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 12P GAIN MUTATED | 36 | 86 | 79 | 26 |
| 12P GAIN WILD-TYPE | 77 | 66 | 75 | 53 |
Figure S104. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00216 (Fisher's exact test), Q value = 0.011
Table S105. Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 12P GAIN MUTATED | 63 | 100 | 64 |
| 12P GAIN WILD-TYPE | 115 | 89 | 67 |
Figure S105. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0295 (Fisher's exact test), Q value = 0.084
Table S106. Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 12P GAIN MUTATED | 53 | 77 | 46 | 27 | 16 |
| 12P GAIN WILD-TYPE | 68 | 57 | 75 | 35 | 21 |
Figure S106. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00983 (Fisher's exact test), Q value = 0.036
Table S107. Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 12P GAIN MUTATED | 51 | 54 | 93 | 21 |
| 12P GAIN WILD-TYPE | 38 | 64 | 106 | 48 |
Figure S107. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0235 (Fisher's exact test), Q value = 0.072
Table S108. Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 12P GAIN MUTATED | 30 | 65 | 59 |
| 12P GAIN WILD-TYPE | 59 | 64 | 57 |
Figure S108. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0015 (Fisher's exact test), Q value = 0.0081
Table S109. Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 12P GAIN MUTATED | 14 | 86 | 54 |
| 12P GAIN WILD-TYPE | 25 | 65 | 90 |
Figure S109. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0239 (Fisher's exact test), Q value = 0.073
Table S110. Gene #24: '12q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 12Q GAIN MUTATED | 8 | 20 | 10 | 15 |
| 12Q GAIN WILD-TYPE | 34 | 32 | 22 | 13 |
Figure S110. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S111. Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 12Q GAIN MUTATED | 33 | 75 | 45 |
| 12Q GAIN WILD-TYPE | 149 | 91 | 108 |
Figure S111. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00633 (Fisher's exact test), Q value = 0.025
Table S112. Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 12Q GAIN MUTATED | 32 | 47 | 29 |
| 12Q GAIN WILD-TYPE | 120 | 75 | 64 |
Figure S112. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00334 (Fisher's exact test), Q value = 0.015
Table S113. Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 12Q GAIN MUTATED | 22 | 61 | 47 | 21 |
| 12Q GAIN WILD-TYPE | 91 | 91 | 107 | 58 |
Figure S113. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00097 (Fisher's exact test), Q value = 0.0058
Table S114. Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 12Q GAIN MUTATED | 36 | 66 | 49 |
| 12Q GAIN WILD-TYPE | 142 | 123 | 82 |
Figure S114. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00952 (Fisher's exact test), Q value = 0.035
Table S115. Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 12Q GAIN MUTATED | 16 | 34 | 43 |
| 12Q GAIN WILD-TYPE | 73 | 95 | 73 |
Figure S115. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 8e-04
Table S116. Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 12Q GAIN MUTATED | 3 | 58 | 32 |
| 12Q GAIN WILD-TYPE | 36 | 93 | 112 |
Figure S116. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0223 (Fisher's exact test), Q value = 0.069
Table S117. Gene #26: '14q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 14Q GAIN MUTATED | 19 | 11 | 9 |
| 14Q GAIN WILD-TYPE | 28 | 45 | 42 |
Figure S117. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0403 (Fisher's exact test), Q value = 0.11
Table S118. Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 14Q GAIN MUTATED | 37 | 42 | 50 |
| 14Q GAIN WILD-TYPE | 145 | 124 | 103 |
Figure S118. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00482 (Fisher's exact test), Q value = 0.02
Table S119. Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 14Q GAIN MUTATED | 60 | 46 | 23 |
| 14Q GAIN WILD-TYPE | 118 | 143 | 108 |
Figure S119. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00086 (Fisher's exact test), Q value = 0.0054
Table S120. Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 15Q GAIN MUTATED | 24 | 49 | 32 |
| 15Q GAIN WILD-TYPE | 158 | 117 | 121 |
Figure S120. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00126 (Fisher's exact test), Q value = 0.0071
Table S121. Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 15Q GAIN MUTATED | 20 | 38 | 17 |
| 15Q GAIN WILD-TYPE | 132 | 84 | 76 |
Figure S121. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0015 (Fisher's exact test), Q value = 0.0081
Table S122. Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 15Q GAIN MUTATED | 14 | 47 | 26 | 16 |
| 15Q GAIN WILD-TYPE | 99 | 105 | 128 | 63 |
Figure S122. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.011 (Fisher's exact test), Q value = 0.04
Table S123. Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 15Q GAIN MUTATED | 32 | 52 | 19 |
| 15Q GAIN WILD-TYPE | 146 | 137 | 112 |
Figure S123. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0356 (Fisher's exact test), Q value = 0.096
Table S124. Gene #27: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 15Q GAIN MUTATED | 28 | 22 | 41 | 9 |
| 15Q GAIN WILD-TYPE | 61 | 96 | 158 | 60 |
Figure S124. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00214 (Fisher's exact test), Q value = 0.011
Table S125. Gene #27: '15q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 15Q GAIN MUTATED | 6 | 43 | 18 |
| 15Q GAIN WILD-TYPE | 33 | 108 | 126 |
Figure S125. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0207 (Fisher's exact test), Q value = 0.065
Table S126. Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 16P GAIN MUTATED | 13 | 23 | 41 | 4 |
| 16P GAIN WILD-TYPE | 76 | 95 | 158 | 65 |
Figure S126. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0246 (Fisher's exact test), Q value = 0.074
Table S127. Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 16Q GAIN MUTATED | 21 | 32 | 34 |
| 16Q GAIN WILD-TYPE | 161 | 134 | 119 |
Figure S127. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0271 (Fisher's exact test), Q value = 0.079
Table S128. Gene #29: '16q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 16Q GAIN MUTATED | 15 | 25 | 38 | 4 |
| 16Q GAIN WILD-TYPE | 74 | 93 | 161 | 65 |
Figure S128. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00406 (Fisher's exact test), Q value = 0.018
Table S129. Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 17P GAIN MUTATED | 1 | 11 | 1 | 6 |
| 17P GAIN WILD-TYPE | 41 | 41 | 31 | 22 |
Figure S129. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S130. Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 17P GAIN MUTATED | 11 | 41 | 16 |
| 17P GAIN WILD-TYPE | 171 | 125 | 137 |
Figure S130. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0018 (Fisher's exact test), Q value = 0.0092
Table S131. Gene #30: '17p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 17P GAIN MUTATED | 14 | 30 | 11 |
| 17P GAIN WILD-TYPE | 138 | 92 | 82 |
Figure S131. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0044
Table S132. Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 17P GAIN MUTATED | 9 | 36 | 16 | 7 |
| 17P GAIN WILD-TYPE | 104 | 116 | 138 | 72 |
Figure S132. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00095 (Fisher's exact test), Q value = 0.0058
Table S133. Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17P GAIN MUTATED | 12 | 38 | 18 |
| 17P GAIN WILD-TYPE | 166 | 151 | 113 |
Figure S133. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0166 (Fisher's exact test), Q value = 0.054
Table S134. Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 17P GAIN MUTATED | 12 | 25 | 8 | 12 | 6 |
| 17P GAIN WILD-TYPE | 109 | 109 | 113 | 50 | 31 |
Figure S134. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00734 (Fisher's exact test), Q value = 0.028
Table S135. Gene #30: '17p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 17P GAIN MUTATED | 2 | 31 | 14 |
| 17P GAIN WILD-TYPE | 37 | 120 | 130 |
Figure S135. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00156 (Fisher's exact test), Q value = 0.0083
Table S136. Gene #31: '17q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 17Q GAIN MUTATED | 7 | 27 | 7 | 9 |
| 17Q GAIN WILD-TYPE | 35 | 25 | 25 | 19 |
Figure S136. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00054 (Fisher's exact test), Q value = 0.0038
Table S137. Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 17Q GAIN MUTATED | 12 | 29 | 9 |
| 17Q GAIN WILD-TYPE | 35 | 27 | 42 |
Figure S137. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S138. Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 17Q GAIN MUTATED | 32 | 91 | 35 |
| 17Q GAIN WILD-TYPE | 150 | 75 | 118 |
Figure S138. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S139. Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 17Q GAIN MUTATED | 31 | 61 | 25 |
| 17Q GAIN WILD-TYPE | 121 | 61 | 68 |
Figure S139. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S140. Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 17Q GAIN MUTATED | 19 | 76 | 44 | 18 |
| 17Q GAIN WILD-TYPE | 94 | 76 | 110 | 61 |
Figure S140. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S141. Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17Q GAIN MUTATED | 32 | 88 | 37 |
| 17Q GAIN WILD-TYPE | 146 | 101 | 94 |
Figure S141. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00048 (Fisher's exact test), Q value = 0.0036
Table S142. Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 17Q GAIN MUTATED | 38 | 55 | 20 | 21 | 13 |
| 17Q GAIN WILD-TYPE | 83 | 79 | 101 | 41 | 24 |
Figure S142. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.04
Table S143. Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 17Q GAIN MUTATED | 40 | 34 | 58 | 15 |
| 17Q GAIN WILD-TYPE | 49 | 84 | 141 | 54 |
Figure S143. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00053 (Fisher's exact test), Q value = 0.0038
Table S144. Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 17Q GAIN MUTATED | 14 | 44 | 46 |
| 17Q GAIN WILD-TYPE | 75 | 85 | 70 |
Figure S144. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S145. Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 17Q GAIN MUTATED | 8 | 66 | 30 |
| 17Q GAIN WILD-TYPE | 31 | 85 | 114 |
Figure S145. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00796 (Fisher's exact test), Q value = 0.03
Table S146. Gene #32: '18p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 18P GAIN MUTATED | 6 | 24 | 9 | 7 |
| 18P GAIN WILD-TYPE | 36 | 28 | 23 | 21 |
Figure S146. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00114 (Fisher's exact test), Q value = 0.0066
Table S147. Gene #32: '18p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 18P GAIN MUTATED | 9 | 27 | 10 |
| 18P GAIN WILD-TYPE | 38 | 29 | 41 |
Figure S147. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S148. Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 18P GAIN MUTATED | 33 | 76 | 41 |
| 18P GAIN WILD-TYPE | 149 | 90 | 112 |
Figure S148. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S149. Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 18P GAIN MUTATED | 26 | 55 | 31 |
| 18P GAIN WILD-TYPE | 126 | 67 | 62 |
Figure S149. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00099 (Fisher's exact test), Q value = 0.0058
Table S150. Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 18P GAIN MUTATED | 27 | 64 | 42 | 16 |
| 18P GAIN WILD-TYPE | 86 | 88 | 112 | 63 |
Figure S150. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S151. Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 18P GAIN MUTATED | 35 | 81 | 33 |
| 18P GAIN WILD-TYPE | 143 | 108 | 98 |
Figure S151. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0165 (Fisher's exact test), Q value = 0.054
Table S152. Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 18P GAIN MUTATED | 31 | 51 | 25 | 21 | 14 |
| 18P GAIN WILD-TYPE | 90 | 83 | 96 | 41 | 23 |
Figure S152. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0038
Table S153. Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 18P GAIN MUTATED | 7 | 61 | 31 |
| 18P GAIN WILD-TYPE | 32 | 90 | 113 |
Figure S153. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0164 (Fisher's exact test), Q value = 0.054
Table S154. Gene #33: '18q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 18Q GAIN MUTATED | 5 | 20 | 5 | 7 |
| 18Q GAIN WILD-TYPE | 37 | 32 | 27 | 21 |
Figure S154. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0143 (Fisher's exact test), Q value = 0.049
Table S155. Gene #33: '18q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 18Q GAIN MUTATED | 7 | 21 | 9 |
| 18Q GAIN WILD-TYPE | 40 | 35 | 42 |
Figure S155. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S156. Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 18Q GAIN MUTATED | 23 | 57 | 24 |
| 18Q GAIN WILD-TYPE | 159 | 109 | 129 |
Figure S156. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00139 (Fisher's exact test), Q value = 0.0077
Table S157. Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 18Q GAIN MUTATED | 19 | 37 | 18 |
| 18Q GAIN WILD-TYPE | 133 | 85 | 75 |
Figure S157. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00076 (Fisher's exact test), Q value = 0.0048
Table S158. Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 18Q GAIN MUTATED | 16 | 46 | 32 | 8 |
| 18Q GAIN WILD-TYPE | 97 | 106 | 122 | 71 |
Figure S158. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00025 (Fisher's exact test), Q value = 0.002
Table S159. Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 18Q GAIN MUTATED | 22 | 56 | 24 |
| 18Q GAIN WILD-TYPE | 156 | 133 | 107 |
Figure S159. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0329 (Fisher's exact test), Q value = 0.091
Table S160. Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 18Q GAIN MUTATED | 26 | 20 | 45 | 8 |
| 18Q GAIN WILD-TYPE | 63 | 98 | 154 | 61 |
Figure S160. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00217 (Fisher's exact test), Q value = 0.011
Table S161. Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 18Q GAIN MUTATED | 4 | 41 | 18 |
| 18Q GAIN WILD-TYPE | 35 | 110 | 126 |
Figure S161. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0464 (Fisher's exact test), Q value = 0.12
Table S162. Gene #34: '19p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 19P GAIN MUTATED | 7 | 16 | 2 | 5 |
| 19P GAIN WILD-TYPE | 35 | 36 | 30 | 23 |
Figure S162. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S163. Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 19P GAIN MUTATED | 30 | 65 | 16 |
| 19P GAIN WILD-TYPE | 152 | 101 | 137 |
Figure S163. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0016
Table S164. Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 19P GAIN MUTATED | 24 | 45 | 18 |
| 19P GAIN WILD-TYPE | 128 | 77 | 75 |
Figure S164. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0229 (Fisher's exact test), Q value = 0.071
Table S165. Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 60 | 73 | 61 |
| 19P GAIN MUTATED | 19 | 10 | 18 |
| 19P GAIN WILD-TYPE | 41 | 63 | 43 |
Figure S165. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.0014
Table S166. Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 19P GAIN MUTATED | 18 | 52 | 31 | 9 |
| 19P GAIN WILD-TYPE | 95 | 100 | 123 | 70 |
Figure S166. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00221 (Fisher's exact test), Q value = 0.011
Table S167. Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 19P GAIN MUTATED | 27 | 57 | 26 |
| 19P GAIN WILD-TYPE | 151 | 132 | 105 |
Figure S167. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00159 (Fisher's exact test), Q value = 0.0084
Table S168. Gene #34: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 19P GAIN MUTATED | 34 | 28 | 34 | 13 |
| 19P GAIN WILD-TYPE | 55 | 90 | 165 | 56 |
Figure S168. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00539 (Fisher's exact test), Q value = 0.022
Table S169. Gene #34: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 19P GAIN MUTATED | 4 | 46 | 26 |
| 19P GAIN WILD-TYPE | 35 | 105 | 118 |
Figure S169. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00054
Table S170. Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 19Q GAIN MUTATED | 42 | 74 | 43 |
| 19Q GAIN WILD-TYPE | 140 | 92 | 110 |
Figure S170. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0272 (Fisher's exact test), Q value = 0.079
Table S171. Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 19Q GAIN MUTATED | 48 | 51 | 23 |
| 19Q GAIN WILD-TYPE | 104 | 71 | 70 |
Figure S171. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0221 (Fisher's exact test), Q value = 0.069
Table S172. Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 19Q GAIN MUTATED | 27 | 58 | 53 | 18 |
| 19Q GAIN WILD-TYPE | 86 | 94 | 101 | 61 |
Figure S172. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0196 (Fisher's exact test), Q value = 0.062
Table S173. Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 20P GAIN MUTATED | 23 | 32 | 9 | 12 |
| 20P GAIN WILD-TYPE | 19 | 20 | 23 | 16 |
Figure S173. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0221 (Fisher's exact test), Q value = 0.069
Table S174. Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 20P GAIN MUTATED | 27 | 32 | 17 |
| 20P GAIN WILD-TYPE | 20 | 24 | 34 |
Figure S174. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S175. Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 20P GAIN MUTATED | 68 | 107 | 86 |
| 20P GAIN WILD-TYPE | 114 | 59 | 67 |
Figure S175. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00068 (Fisher's exact test), Q value = 0.0044
Table S176. Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 20P GAIN MUTATED | 71 | 82 | 42 |
| 20P GAIN WILD-TYPE | 81 | 40 | 51 |
Figure S176. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00053 (Fisher's exact test), Q value = 0.0038
Table S177. Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 20Q GAIN MUTATED | 72 | 86 | 93 |
| 20Q GAIN WILD-TYPE | 110 | 80 | 60 |
Figure S177. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0291 (Fisher's exact test), Q value = 0.083
Table S178. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 20Q GAIN MUTATED | 35 | 53 | 113 | 36 |
| 20Q GAIN WILD-TYPE | 54 | 65 | 86 | 33 |
Figure S178. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00827 (Fisher's exact test), Q value = 0.031
Table S179. Gene #39: '22q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 22Q GAIN MUTATED | 21 | 31 | 10 | 7 |
| 22Q GAIN WILD-TYPE | 21 | 21 | 22 | 21 |
Figure S179. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0287 (Fisher's exact test), Q value = 0.082
Table S180. Gene #39: '22q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 22Q GAIN MUTATED | 21 | 32 | 16 |
| 22Q GAIN WILD-TYPE | 26 | 24 | 35 |
Figure S180. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00453 (Fisher's exact test), Q value = 0.02
Table S181. Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 22Q GAIN MUTATED | 63 | 85 | 73 |
| 22Q GAIN WILD-TYPE | 119 | 81 | 80 |
Figure S181. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.034 (Fisher's exact test), Q value = 0.093
Table S182. Gene #39: '22q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 22Q GAIN MUTATED | 56 | 64 | 42 |
| 22Q GAIN WILD-TYPE | 96 | 58 | 51 |
Figure S182. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00056 (Fisher's exact test), Q value = 0.0039
Table S183. Gene #39: '22q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 22Q GAIN MUTATED | 50 | 86 | 52 | 31 |
| 22Q GAIN WILD-TYPE | 63 | 66 | 102 | 48 |
Figure S183. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.0012
Table S184. Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 22Q GAIN MUTATED | 84 | 98 | 37 |
| 22Q GAIN WILD-TYPE | 94 | 91 | 94 |
Figure S184. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00054
Table S185. Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| XP GAIN MUTATED | 9 | 28 | 28 |
| XP GAIN WILD-TYPE | 173 | 138 | 125 |
Figure S185. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00467 (Fisher's exact test), Q value = 0.02
Table S186. Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| XP GAIN MUTATED | 10 | 25 | 27 | 3 |
| XP GAIN WILD-TYPE | 103 | 127 | 127 | 76 |
Figure S186. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00809 (Fisher's exact test), Q value = 0.03
Table S187. Gene #40: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| XP GAIN MUTATED | 11 | 29 | 9 | 6 | 5 |
| XP GAIN WILD-TYPE | 110 | 105 | 112 | 56 | 32 |
Figure S187. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0335 (Fisher's exact test), Q value = 0.092
Table S188. Gene #41: 'xq gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| XQ GAIN MUTATED | 10 | 15 | 4 |
| XQ GAIN WILD-TYPE | 37 | 41 | 47 |
Figure S188. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S189. Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| XQ GAIN MUTATED | 14 | 45 | 24 |
| XQ GAIN WILD-TYPE | 168 | 121 | 129 |
Figure S189. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00348 (Fisher's exact test), Q value = 0.016
Table S190. Gene #41: 'xq gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| XQ GAIN MUTATED | 15 | 30 | 12 |
| XQ GAIN WILD-TYPE | 137 | 92 | 81 |
Figure S190. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00693 (Fisher's exact test), Q value = 0.027
Table S191. Gene #41: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| XQ GAIN MUTATED | 14 | 38 | 24 | 7 |
| XQ GAIN WILD-TYPE | 99 | 114 | 130 | 72 |
Figure S191. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00865 (Fisher's exact test), Q value = 0.032
Table S192. Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| XQ GAIN MUTATED | 21 | 44 | 18 |
| XQ GAIN WILD-TYPE | 157 | 145 | 113 |
Figure S192. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00045
Table S193. Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 1P LOSS MUTATED | 8 | 29 | 8 | 3 |
| 1P LOSS WILD-TYPE | 34 | 23 | 24 | 25 |
Figure S193. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S194. Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 1P LOSS MUTATED | 8 | 31 | 9 |
| 1P LOSS WILD-TYPE | 39 | 25 | 42 |
Figure S194. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S195. Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 1P LOSS MUTATED | 31 | 97 | 24 |
| 1P LOSS WILD-TYPE | 151 | 69 | 129 |
Figure S195. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S196. Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 1P LOSS MUTATED | 23 | 64 | 22 |
| 1P LOSS WILD-TYPE | 129 | 58 | 71 |
Figure S196. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S197. Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 1P LOSS MUTATED | 19 | 83 | 31 | 18 |
| 1P LOSS WILD-TYPE | 94 | 69 | 123 | 61 |
Figure S197. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S198. Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 1P LOSS MUTATED | 28 | 98 | 25 |
| 1P LOSS WILD-TYPE | 150 | 91 | 106 |
Figure S198. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00137 (Fisher's exact test), Q value = 0.0076
Table S199. Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 1P LOSS MUTATED | 36 | 48 | 22 | 28 | 9 |
| 1P LOSS WILD-TYPE | 85 | 86 | 99 | 34 | 28 |
Figure S199. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S200. Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 1P LOSS MUTATED | 49 | 32 | 52 | 10 |
| 1P LOSS WILD-TYPE | 40 | 86 | 147 | 59 |
Figure S200. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00081 (Fisher's exact test), Q value = 0.0051
Table S201. Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 1P LOSS MUTATED | 16 | 33 | 48 |
| 1P LOSS WILD-TYPE | 73 | 96 | 68 |
Figure S201. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0028
Table S202. Gene #42: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 1P LOSS MUTATED | 6 | 60 | 31 |
| 1P LOSS WILD-TYPE | 33 | 91 | 113 |
Figure S202. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00229 (Fisher's exact test), Q value = 0.011
Table S203. Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 1Q LOSS MUTATED | 11 | 30 | 19 |
| 1Q LOSS WILD-TYPE | 171 | 136 | 134 |
Figure S203. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0347 (Fisher's exact test), Q value = 0.095
Table S204. Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 1Q LOSS MUTATED | 9 | 27 | 18 | 5 |
| 1Q LOSS WILD-TYPE | 104 | 125 | 136 | 74 |
Figure S204. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0269 (Fisher's exact test), Q value = 0.079
Table S205. Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 1Q LOSS MUTATED | 16 | 32 | 11 |
| 1Q LOSS WILD-TYPE | 162 | 157 | 120 |
Figure S205. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0292 (Fisher's exact test), Q value = 0.083
Table S206. Gene #44: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 2P LOSS MUTATED | 4 | 6 | 11 |
| 2P LOSS WILD-TYPE | 174 | 183 | 120 |
Figure S206. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00659 (Fisher's exact test), Q value = 0.026
Table S207. Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 2P LOSS MUTATED | 9 | 9 | 0 | 1 | 1 |
| 2P LOSS WILD-TYPE | 112 | 125 | 121 | 61 | 36 |
Figure S207. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0376 (Fisher's exact test), Q value = 0.1
Table S208. Gene #44: '2p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 2P LOSS MUTATED | 1 | 2 | 8 |
| 2P LOSS WILD-TYPE | 88 | 127 | 108 |
Figure S208. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00057 (Fisher's exact test), Q value = 0.0039
Table S209. Gene #44: '2p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 2P LOSS MUTATED | 0 | 11 | 0 |
| 2P LOSS WILD-TYPE | 39 | 140 | 144 |
Figure S209. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0256 (Fisher's exact test), Q value = 0.076
Table S210. Gene #45: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 2Q LOSS MUTATED | 8 | 17 | 17 |
| 2Q LOSS WILD-TYPE | 170 | 172 | 114 |
Figure S210. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S211. Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 2Q LOSS MUTATED | 15 | 18 | 0 | 5 | 3 |
| 2Q LOSS WILD-TYPE | 106 | 116 | 121 | 57 | 34 |
Figure S211. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00142 (Fisher's exact test), Q value = 0.0078
Table S212. Gene #45: '2q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 2Q LOSS MUTATED | 2 | 21 | 4 |
| 2Q LOSS WILD-TYPE | 37 | 130 | 140 |
Figure S212. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00209 (Fisher's exact test), Q value = 0.01
Table S213. Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 3P LOSS MUTATED | 79 | 75 | 69 |
| 3P LOSS WILD-TYPE | 73 | 47 | 24 |
Figure S213. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0018
Table S214. Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 3P LOSS MUTATED | 62 | 79 | 123 | 26 |
| 3P LOSS WILD-TYPE | 27 | 39 | 76 | 43 |
Figure S214. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0311 (Fisher's exact test), Q value = 0.087
Table S215. Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 3P LOSS MUTATED | 44 | 81 | 78 |
| 3P LOSS WILD-TYPE | 45 | 48 | 38 |
Figure S215. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00132 (Fisher's exact test), Q value = 0.0074
Table S216. Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 4P LOSS MUTATED | 30 | 40 | 12 | 15 |
| 4P LOSS WILD-TYPE | 12 | 12 | 20 | 13 |
Figure S216. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.0011
Table S217. Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 4P LOSS MUTATED | 33 | 44 | 20 |
| 4P LOSS WILD-TYPE | 14 | 12 | 31 |
Figure S217. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S218. Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 4P LOSS MUTATED | 85 | 139 | 91 |
| 4P LOSS WILD-TYPE | 97 | 27 | 62 |
Figure S218. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S219. Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 4P LOSS MUTATED | 70 | 99 | 61 |
| 4P LOSS WILD-TYPE | 82 | 23 | 32 |
Figure S219. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S220. Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 4P LOSS MUTATED | 74 | 119 | 81 | 40 |
| 4P LOSS WILD-TYPE | 39 | 33 | 73 | 39 |
Figure S220. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S221. Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 4P LOSS MUTATED | 98 | 150 | 66 |
| 4P LOSS WILD-TYPE | 80 | 39 | 65 |
Figure S221. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00065 (Fisher's exact test), Q value = 0.0043
Table S222. Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 4P LOSS MUTATED | 80 | 100 | 59 | 41 | 21 |
| 4P LOSS WILD-TYPE | 41 | 34 | 62 | 21 | 16 |
Figure S222. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S223. Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 4P LOSS MUTATED | 39 | 79 | 92 |
| 4P LOSS WILD-TYPE | 50 | 50 | 24 |
Figure S223. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S224. Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 4P LOSS MUTATED | 17 | 118 | 75 |
| 4P LOSS WILD-TYPE | 22 | 33 | 69 |
Figure S224. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00235 (Fisher's exact test), Q value = 0.011
Table S225. Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 4Q LOSS MUTATED | 26 | 38 | 10 | 17 |
| 4Q LOSS WILD-TYPE | 16 | 14 | 22 | 11 |
Figure S225. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00103 (Fisher's exact test), Q value = 0.006
Table S226. Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 4Q LOSS MUTATED | 30 | 41 | 20 |
| 4Q LOSS WILD-TYPE | 17 | 15 | 31 |
Figure S226. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S227. Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 4Q LOSS MUTATED | 86 | 132 | 80 |
| 4Q LOSS WILD-TYPE | 96 | 34 | 73 |
Figure S227. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S228. Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 4Q LOSS MUTATED | 73 | 94 | 53 |
| 4Q LOSS WILD-TYPE | 79 | 28 | 40 |
Figure S228. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00027
Table S229. Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 4Q LOSS MUTATED | 64 | 114 | 85 | 34 |
| 4Q LOSS WILD-TYPE | 49 | 38 | 69 | 45 |
Figure S229. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0022
Table S230. Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 4Q LOSS MUTATED | 96 | 134 | 67 |
| 4Q LOSS WILD-TYPE | 82 | 55 | 64 |
Figure S230. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00286 (Fisher's exact test), Q value = 0.013
Table S231. Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 4Q LOSS MUTATED | 76 | 89 | 54 | 42 | 23 |
| 4Q LOSS WILD-TYPE | 45 | 45 | 67 | 20 | 14 |
Figure S231. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0303 (Fisher's exact test), Q value = 0.085
Table S232. Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 4Q LOSS MUTATED | 63 | 68 | 120 | 33 |
| 4Q LOSS WILD-TYPE | 26 | 50 | 79 | 36 |
Figure S232. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00064 (Fisher's exact test), Q value = 0.0043
Table S233. Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 4Q LOSS MUTATED | 45 | 69 | 85 |
| 4Q LOSS WILD-TYPE | 44 | 60 | 31 |
Figure S233. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00045
Table S234. Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 4Q LOSS MUTATED | 22 | 110 | 67 |
| 4Q LOSS WILD-TYPE | 17 | 41 | 77 |
Figure S234. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00435 (Fisher's exact test), Q value = 0.019
Table S235. Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 5P LOSS MUTATED | 16 | 31 | 31 |
| 5P LOSS WILD-TYPE | 166 | 135 | 122 |
Figure S235. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00422 (Fisher's exact test), Q value = 0.019
Table S236. Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 5P LOSS MUTATED | 11 | 20 | 20 |
| 5P LOSS WILD-TYPE | 141 | 102 | 73 |
Figure S236. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0336 (Fisher's exact test), Q value = 0.092
Table S237. Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 5P LOSS MUTATED | 4 | 9 | 7 | 13 |
| 5P LOSS WILD-TYPE | 50 | 32 | 45 | 34 |
Figure S237. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0384 (Fisher's exact test), Q value = 0.1
Table S238. Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 5P LOSS MUTATED | 20 | 26 | 9 | 13 | 5 |
| 5P LOSS WILD-TYPE | 101 | 108 | 112 | 49 | 32 |
Figure S238. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0155 (Fisher's exact test), Q value = 0.052
Table S239. Gene #50: '5p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 5P LOSS MUTATED | 8 | 15 | 26 |
| 5P LOSS WILD-TYPE | 81 | 114 | 90 |
Figure S239. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0016
Table S240. Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 5Q LOSS MUTATED | 84 | 109 | 98 |
| 5Q LOSS WILD-TYPE | 98 | 57 | 55 |
Figure S240. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00239 (Fisher's exact test), Q value = 0.011
Table S241. Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 5Q LOSS MUTATED | 71 | 82 | 55 |
| 5Q LOSS WILD-TYPE | 81 | 40 | 38 |
Figure S241. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.006 (Fisher's exact test), Q value = 0.024
Table S242. Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 5Q LOSS MUTATED | 62 | 105 | 83 | 38 |
| 5Q LOSS WILD-TYPE | 51 | 47 | 71 | 41 |
Figure S242. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00033 (Fisher's exact test), Q value = 0.0026
Table S243. Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 5Q LOSS MUTATED | 90 | 131 | 67 |
| 5Q LOSS WILD-TYPE | 88 | 58 | 64 |
Figure S243. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0198 (Fisher's exact test), Q value = 0.063
Table S244. Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 5Q LOSS MUTATED | 55 | 70 | 122 | 28 |
| 5Q LOSS WILD-TYPE | 34 | 48 | 77 | 41 |
Figure S244. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0141 (Fisher's exact test), Q value = 0.048
Table S245. Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 5Q LOSS MUTATED | 39 | 82 | 68 |
| 5Q LOSS WILD-TYPE | 50 | 47 | 48 |
Figure S245. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0349 (Fisher's exact test), Q value = 0.095
Table S246. Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 6P LOSS MUTATED | 6 | 18 | 5 | 3 |
| 6P LOSS WILD-TYPE | 36 | 34 | 27 | 25 |
Figure S246. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0144 (Fisher's exact test), Q value = 0.049
Table S247. Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 6P LOSS MUTATED | 6 | 19 | 7 |
| 6P LOSS WILD-TYPE | 41 | 37 | 44 |
Figure S247. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00392 (Fisher's exact test), Q value = 0.017
Table S248. Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 6P LOSS MUTATED | 33 | 52 | 27 |
| 6P LOSS WILD-TYPE | 149 | 114 | 126 |
Figure S248. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.0011
Table S249. Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 6P LOSS MUTATED | 24 | 45 | 16 |
| 6P LOSS WILD-TYPE | 128 | 77 | 77 |
Figure S249. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S250. Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 6P LOSS MUTATED | 20 | 56 | 21 | 14 |
| 6P LOSS WILD-TYPE | 93 | 96 | 133 | 65 |
Figure S250. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S251. Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6P LOSS MUTATED | 29 | 65 | 17 |
| 6P LOSS WILD-TYPE | 149 | 124 | 114 |
Figure S251. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00469 (Fisher's exact test), Q value = 0.02
Table S252. Gene #53: '6q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 6Q LOSS MUTATED | 6 | 21 | 4 | 4 |
| 6Q LOSS WILD-TYPE | 36 | 31 | 28 | 24 |
Figure S252. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00103 (Fisher's exact test), Q value = 0.006
Table S253. Gene #53: '6q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 6Q LOSS MUTATED | 8 | 22 | 5 |
| 6Q LOSS WILD-TYPE | 39 | 34 | 46 |
Figure S253. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0254 (Fisher's exact test), Q value = 0.075
Table S254. Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 6Q LOSS MUTATED | 32 | 49 | 32 |
| 6Q LOSS WILD-TYPE | 150 | 117 | 121 |
Figure S254. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00277 (Fisher's exact test), Q value = 0.013
Table S255. Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 6Q LOSS MUTATED | 27 | 42 | 17 |
| 6Q LOSS WILD-TYPE | 125 | 80 | 76 |
Figure S255. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.0092
Table S256. Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 6Q LOSS MUTATED | 20 | 51 | 25 | 16 |
| 6Q LOSS WILD-TYPE | 93 | 101 | 129 | 63 |
Figure S256. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0238 (Fisher's exact test), Q value = 0.072
Table S257. Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 6Q LOSS MUTATED | 34 | 55 | 23 |
| 6Q LOSS WILD-TYPE | 144 | 134 | 108 |
Figure S257. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0018
Table S258. Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 7P LOSS MUTATED | 10 | 17 | 31 |
| 7P LOSS WILD-TYPE | 172 | 149 | 122 |
Figure S258. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00561 (Fisher's exact test), Q value = 0.023
Table S259. Gene #54: '7p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7P LOSS MUTATED | 4 | 10 | 34 | 5 |
| 7P LOSS WILD-TYPE | 85 | 108 | 165 | 64 |
Figure S259. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00285 (Fisher's exact test), Q value = 0.013
Table S260. Gene #55: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 7Q LOSS MUTATED | 18 | 8 | 25 |
| 7Q LOSS WILD-TYPE | 164 | 158 | 128 |
Figure S260. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00072
Table S261. Gene #55: '7q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 7Q LOSS MUTATED | 10 | 5 | 30 | 6 |
| 7Q LOSS WILD-TYPE | 103 | 147 | 124 | 73 |
Figure S261. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00027
Table S262. Gene #55: '7q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 7Q LOSS MUTATED | 17 | 7 | 27 |
| 7Q LOSS WILD-TYPE | 161 | 182 | 104 |
Figure S262. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0336 (Fisher's exact test), Q value = 0.092
Table S263. Gene #55: '7q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 7Q LOSS MUTATED | 3 | 14 | 26 | 4 |
| 7Q LOSS WILD-TYPE | 86 | 104 | 173 | 65 |
Figure S263. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00533 (Fisher's exact test), Q value = 0.022
Table S264. Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 8P LOSS MUTATED | 72 | 85 | 87 |
| 8P LOSS WILD-TYPE | 110 | 81 | 66 |
Figure S264. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00093 (Fisher's exact test), Q value = 0.0057
Table S265. Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 8P LOSS MUTATED | 60 | 76 | 47 |
| 8P LOSS WILD-TYPE | 92 | 46 | 46 |
Figure S265. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.015 (Fisher's exact test), Q value = 0.05
Table S266. Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 8P LOSS MUTATED | 48 | 69 | 91 | 25 |
| 8P LOSS WILD-TYPE | 41 | 49 | 108 | 44 |
Figure S266. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0349 (Fisher's exact test), Q value = 0.095
Table S267. Gene #57: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 8Q LOSS MUTATED | 11 | 21 | 9 |
| 8Q LOSS WILD-TYPE | 141 | 101 | 84 |
Figure S267. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0419 (Fisher's exact test), Q value = 0.11
Table S268. Gene #57: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 8Q LOSS MUTATED | 10 | 25 | 13 |
| 8Q LOSS WILD-TYPE | 168 | 164 | 118 |
Figure S268. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00717 (Fisher's exact test), Q value = 0.028
Table S269. Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 9P LOSS MUTATED | 35 | 27 | 19 | 15 |
| 9P LOSS WILD-TYPE | 7 | 25 | 13 | 13 |
Figure S269. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00119 (Fisher's exact test), Q value = 0.0068
Table S270. Gene #58: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9P LOSS MUTATED | 39 | 28 | 29 |
| 9P LOSS WILD-TYPE | 8 | 28 | 22 |
Figure S270. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S271. Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 9P LOSS MUTATED | 99 | 90 | 121 |
| 9P LOSS WILD-TYPE | 83 | 76 | 32 |
Figure S271. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0237 (Fisher's exact test), Q value = 0.072
Table S272. Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 9P LOSS MUTATED | 90 | 68 | 68 |
| 9P LOSS WILD-TYPE | 62 | 54 | 25 |
Figure S272. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S273. Gene #58: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 9P LOSS MUTATED | 89 | 74 | 104 | 40 |
| 9P LOSS WILD-TYPE | 24 | 78 | 50 | 39 |
Figure S273. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00027
Table S274. Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9P LOSS MUTATED | 133 | 96 | 78 |
| 9P LOSS WILD-TYPE | 45 | 93 | 53 |
Figure S274. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.044 (Fisher's exact test), Q value = 0.11
Table S275. Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 9P LOSS MUTATED | 74 | 84 | 74 | 31 | 30 |
| 9P LOSS WILD-TYPE | 47 | 50 | 47 | 31 | 7 |
Figure S275. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00033 (Fisher's exact test), Q value = 0.0026
Table S276. Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9P LOSS MUTATED | 44 | 75 | 141 | 33 |
| 9P LOSS WILD-TYPE | 45 | 43 | 58 | 36 |
Figure S276. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.028 (Fisher's exact test), Q value = 0.08
Table S277. Gene #58: '9p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 9P LOSS MUTATED | 31 | 94 | 81 |
| 9P LOSS WILD-TYPE | 8 | 57 | 63 |
Figure S277. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S278. Gene #59: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 9Q LOSS MUTATED | 29 | 11 | 21 | 13 |
| 9Q LOSS WILD-TYPE | 13 | 41 | 11 | 15 |
Figure S278. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S279. Gene #59: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 9Q LOSS MUTATED | 32 | 12 | 30 |
| 9Q LOSS WILD-TYPE | 15 | 44 | 21 |
Figure S279. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S280. Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 9Q LOSS MUTATED | 89 | 44 | 112 |
| 9Q LOSS WILD-TYPE | 93 | 122 | 41 |
Figure S280. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S281. Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 9Q LOSS MUTATED | 87 | 31 | 62 |
| 9Q LOSS WILD-TYPE | 65 | 91 | 31 |
Figure S281. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0135 (Fisher's exact test), Q value = 0.047
Table S282. Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 9Q LOSS MUTATED | 20 | 19 | 34 | 18 |
| 9Q LOSS WILD-TYPE | 34 | 22 | 18 | 29 |
Figure S282. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S283. Gene #59: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 9Q LOSS MUTATED | 78 | 28 | 95 | 42 |
| 9Q LOSS WILD-TYPE | 35 | 124 | 59 | 37 |
Figure S283. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S284. Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 9Q LOSS MUTATED | 127 | 42 | 74 |
| 9Q LOSS WILD-TYPE | 51 | 147 | 57 |
Figure S284. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S285. Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 9Q LOSS MUTATED | 57 | 59 | 72 | 14 | 29 |
| 9Q LOSS WILD-TYPE | 64 | 75 | 49 | 48 | 8 |
Figure S285. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S286. Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 9Q LOSS MUTATED | 18 | 54 | 128 | 31 |
| 9Q LOSS WILD-TYPE | 71 | 64 | 71 | 38 |
Figure S286. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00408 (Fisher's exact test), Q value = 0.018
Table S287. Gene #59: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 9Q LOSS MUTATED | 56 | 64 | 46 |
| 9Q LOSS WILD-TYPE | 33 | 65 | 70 |
Figure S287. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00097
Table S288. Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 9Q LOSS MUTATED | 31 | 63 | 72 |
| 9Q LOSS WILD-TYPE | 8 | 88 | 72 |
Figure S288. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00045
Table S289. Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 10P LOSS MUTATED | 55 | 90 | 69 |
| 10P LOSS WILD-TYPE | 127 | 76 | 84 |
Figure S289. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S290. Gene #60: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 10P LOSS MUTATED | 41 | 79 | 34 |
| 10P LOSS WILD-TYPE | 111 | 43 | 59 |
Figure S290. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S291. Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 10P LOSS MUTATED | 39 | 91 | 56 | 27 |
| 10P LOSS WILD-TYPE | 74 | 61 | 98 | 52 |
Figure S291. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00062
Table S292. Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 10P LOSS MUTATED | 67 | 104 | 42 |
| 10P LOSS WILD-TYPE | 111 | 85 | 89 |
Figure S292. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00038 (Fisher's exact test), Q value = 0.0029
Table S293. Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 10P LOSS MUTATED | 52 | 61 | 35 | 39 | 17 |
| 10P LOSS WILD-TYPE | 69 | 73 | 86 | 23 | 20 |
Figure S293. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S294. Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 10P LOSS MUTATED | 58 | 41 | 90 | 15 |
| 10P LOSS WILD-TYPE | 31 | 77 | 109 | 54 |
Figure S294. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0475 (Fisher's exact test), Q value = 0.12
Table S295. Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 10P LOSS MUTATED | 30 | 50 | 58 |
| 10P LOSS WILD-TYPE | 59 | 79 | 58 |
Figure S295. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00437 (Fisher's exact test), Q value = 0.019
Table S296. Gene #60: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 10P LOSS MUTATED | 18 | 75 | 45 |
| 10P LOSS WILD-TYPE | 21 | 76 | 99 |
Figure S296. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00093 (Fisher's exact test), Q value = 0.0057
Table S297. Gene #61: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 10Q LOSS MUTATED | 13 | 34 | 11 | 8 |
| 10Q LOSS WILD-TYPE | 29 | 18 | 21 | 20 |
Figure S297. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0015
Table S298. Gene #61: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 10Q LOSS MUTATED | 12 | 36 | 18 |
| 10Q LOSS WILD-TYPE | 35 | 20 | 33 |
Figure S298. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00045
Table S299. Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 10Q LOSS MUTATED | 62 | 99 | 68 |
| 10Q LOSS WILD-TYPE | 120 | 67 | 85 |
Figure S299. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S300. Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 10Q LOSS MUTATED | 48 | 81 | 41 |
| 10Q LOSS WILD-TYPE | 104 | 41 | 52 |
Figure S300. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S301. Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 10Q LOSS MUTATED | 44 | 102 | 56 | 26 |
| 10Q LOSS WILD-TYPE | 69 | 50 | 98 | 53 |
Figure S301. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S302. Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 10Q LOSS MUTATED | 69 | 119 | 40 |
| 10Q LOSS WILD-TYPE | 109 | 70 | 91 |
Figure S302. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00055 (Fisher's exact test), Q value = 0.0038
Table S303. Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 10Q LOSS MUTATED | 48 | 72 | 41 | 39 | 18 |
| 10Q LOSS WILD-TYPE | 73 | 62 | 80 | 23 | 19 |
Figure S303. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S304. Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 10Q LOSS MUTATED | 61 | 43 | 96 | 18 |
| 10Q LOSS WILD-TYPE | 28 | 75 | 103 | 51 |
Figure S304. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0149 (Fisher's exact test), Q value = 0.05
Table S305. Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 10Q LOSS MUTATED | 31 | 59 | 64 |
| 10Q LOSS WILD-TYPE | 58 | 70 | 52 |
Figure S305. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00729 (Fisher's exact test), Q value = 0.028
Table S306. Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 10Q LOSS MUTATED | 18 | 83 | 53 |
| 10Q LOSS WILD-TYPE | 21 | 68 | 91 |
Figure S306. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00609 (Fisher's exact test), Q value = 0.024
Table S307. Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 11P LOSS MUTATED | 48 | 57 | 66 |
| 11P LOSS WILD-TYPE | 134 | 109 | 87 |
Figure S307. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00463 (Fisher's exact test), Q value = 0.02
Table S308. Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 11P LOSS MUTATED | 37 | 44 | 41 |
| 11P LOSS WILD-TYPE | 115 | 78 | 52 |
Figure S308. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00325 (Fisher's exact test), Q value = 0.015
Table S309. Gene #62: '11p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 11P LOSS MUTATED | 21 | 9 | 26 | 9 |
| 11P LOSS WILD-TYPE | 33 | 32 | 26 | 38 |
Figure S309. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0063 (Fisher's exact test), Q value = 0.025
Table S310. Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 11Q LOSS MUTATED | 36 | 55 | 50 |
| 11Q LOSS WILD-TYPE | 146 | 111 | 103 |
Figure S310. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00099 (Fisher's exact test), Q value = 0.0058
Table S311. Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 11Q LOSS MUTATED | 29 | 41 | 37 |
| 11Q LOSS WILD-TYPE | 123 | 81 | 56 |
Figure S311. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0233 (Fisher's exact test), Q value = 0.072
Table S312. Gene #64: '12p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 12P LOSS MUTATED | 0 | 3 | 3 | 5 |
| 12P LOSS WILD-TYPE | 42 | 49 | 29 | 23 |
Figure S312. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00512 (Fisher's exact test), Q value = 0.021
Table S313. Gene #64: '12p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 12P LOSS MUTATED | 0 | 3 | 8 |
| 12P LOSS WILD-TYPE | 47 | 53 | 43 |
Figure S313. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0282 (Fisher's exact test), Q value = 0.081
Table S314. Gene #65: '12q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 60 | 73 | 61 |
| 12Q LOSS MUTATED | 3 | 2 | 9 |
| 12Q LOSS WILD-TYPE | 57 | 71 | 52 |
Figure S314. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #5: 'RPPA_CNMF'
P value = 0.0409 (Fisher's exact test), Q value = 0.11
Table S315. Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 13Q LOSS MUTATED | 81 | 81 | 62 |
| 13Q LOSS WILD-TYPE | 71 | 41 | 31 |
Figure S315. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0044
Table S316. Gene #66: '13q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 13Q LOSS MUTATED | 42 | 79 | 85 |
| 13Q LOSS WILD-TYPE | 47 | 50 | 31 |
Figure S316. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0251 (Fisher's exact test), Q value = 0.075
Table S317. Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 13Q LOSS MUTATED | 21 | 105 | 80 |
| 13Q LOSS WILD-TYPE | 18 | 46 | 64 |
Figure S317. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00097
Table S318. Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 14Q LOSS MUTATED | 2 | 20 | 12 | 12 |
| 14Q LOSS WILD-TYPE | 40 | 32 | 20 | 16 |
Figure S318. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0023
Table S319. Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 14Q LOSS MUTATED | 4 | 22 | 20 |
| 14Q LOSS WILD-TYPE | 43 | 34 | 31 |
Figure S319. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0181 (Fisher's exact test), Q value = 0.059
Table S320. Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 14Q LOSS MUTATED | 55 | 69 | 42 |
| 14Q LOSS WILD-TYPE | 127 | 97 | 111 |
Figure S320. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S321. Gene #67: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 14Q LOSS MUTATED | 16 | 63 | 69 | 16 |
| 14Q LOSS WILD-TYPE | 97 | 89 | 85 | 63 |
Figure S321. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S322. Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 14Q LOSS MUTATED | 28 | 75 | 61 |
| 14Q LOSS WILD-TYPE | 150 | 114 | 70 |
Figure S322. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00018 (Fisher's exact test), Q value = 0.0016
Table S323. Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 14Q LOSS MUTATED | 34 | 44 | 28 | 35 | 15 |
| 14Q LOSS WILD-TYPE | 87 | 90 | 93 | 27 | 22 |
Figure S323. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S324. Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 14Q LOSS MUTATED | 51 | 34 | 58 | 13 |
| 14Q LOSS WILD-TYPE | 38 | 84 | 141 | 56 |
Figure S324. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00267 (Fisher's exact test), Q value = 0.013
Table S325. Gene #67: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 14Q LOSS MUTATED | 18 | 52 | 46 |
| 14Q LOSS WILD-TYPE | 71 | 77 | 70 |
Figure S325. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00218 (Fisher's exact test), Q value = 0.011
Table S326. Gene #67: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 14Q LOSS MUTATED | 6 | 65 | 45 |
| 14Q LOSS WILD-TYPE | 33 | 86 | 99 |
Figure S326. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00197 (Fisher's exact test), Q value = 0.0099
Table S327. Gene #68: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 15Q LOSS MUTATED | 21 | 3 | 18 | 12 |
| 15Q LOSS WILD-TYPE | 33 | 38 | 34 | 35 |
Figure S327. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.0277 (Fisher's exact test), Q value = 0.08
Table S328. Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 15Q LOSS MUTATED | 39 | 45 | 25 | 11 | 13 |
| 15Q LOSS WILD-TYPE | 82 | 89 | 96 | 51 | 24 |
Figure S328. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00356 (Fisher's exact test), Q value = 0.016
Table S329. Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 16P LOSS MUTATED | 43 | 59 | 61 |
| 16P LOSS WILD-TYPE | 139 | 107 | 92 |
Figure S329. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0267 (Fisher's exact test), Q value = 0.079
Table S330. Gene #69: '16p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 16P LOSS MUTATED | 21 | 44 | 48 |
| 16P LOSS WILD-TYPE | 68 | 85 | 68 |
Figure S330. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0174 (Fisher's exact test), Q value = 0.056
Table S331. Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 16Q LOSS MUTATED | 52 | 71 | 59 |
| 16Q LOSS WILD-TYPE | 130 | 95 | 94 |
Figure S331. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0018
Table S332. Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 16Q LOSS MUTATED | 39 | 53 | 32 | 24 | 25 |
| 16Q LOSS WILD-TYPE | 82 | 81 | 89 | 38 | 12 |
Figure S332. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00215 (Fisher's exact test), Q value = 0.011
Table S333. Gene #70: '16q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 16Q LOSS MUTATED | 20 | 51 | 52 |
| 16Q LOSS WILD-TYPE | 69 | 78 | 64 |
Figure S333. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.00183 (Fisher's exact test), Q value = 0.0093
Table S334. Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 16Q LOSS MUTATED | 9 | 71 | 43 |
| 16Q LOSS WILD-TYPE | 30 | 80 | 101 |
Figure S334. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00468 (Fisher's exact test), Q value = 0.02
Table S335. Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 17P LOSS MUTATED | 33 | 26 | 22 | 12 |
| 17P LOSS WILD-TYPE | 9 | 26 | 10 | 16 |
Figure S335. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00062
Table S336. Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 17P LOSS MUTATED | 93 | 87 | 111 |
| 17P LOSS WILD-TYPE | 89 | 79 | 42 |
Figure S336. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.04
Table S337. Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 17P LOSS MUTATED | 81 | 60 | 64 |
| 17P LOSS WILD-TYPE | 71 | 62 | 29 |
Figure S337. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00631 (Fisher's exact test), Q value = 0.025
Table S338. Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 54 | 41 | 52 | 47 |
| 17P LOSS MUTATED | 41 | 19 | 26 | 23 |
| 17P LOSS WILD-TYPE | 13 | 22 | 26 | 24 |
Figure S338. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #6: 'RPPA_CHIERARCHICAL'
P value = 0.00169 (Fisher's exact test), Q value = 0.0088
Table S339. Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 17P LOSS MUTATED | 76 | 70 | 99 | 45 |
| 17P LOSS WILD-TYPE | 37 | 82 | 55 | 34 |
Figure S339. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00128 (Fisher's exact test), Q value = 0.0072
Table S340. Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17P LOSS MUTATED | 121 | 93 | 76 |
| 17P LOSS WILD-TYPE | 57 | 96 | 55 |
Figure S340. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00073 (Fisher's exact test), Q value = 0.0046
Table S341. Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 17P LOSS MUTATED | 41 | 76 | 131 | 31 |
| 17P LOSS WILD-TYPE | 48 | 42 | 68 | 38 |
Figure S341. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0102 (Fisher's exact test), Q value = 0.037
Table S342. Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 17Q LOSS MUTATED | 13 | 3 | 7 | 4 |
| 17Q LOSS WILD-TYPE | 29 | 49 | 25 | 24 |
Figure S342. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00498 (Fisher's exact test), Q value = 0.021
Table S343. Gene #72: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 47 | 56 | 51 |
| 17Q LOSS MUTATED | 13 | 3 | 11 |
| 17Q LOSS WILD-TYPE | 34 | 53 | 40 |
Figure S343. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00058 (Fisher's exact test), Q value = 0.004
Table S344. Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 17Q LOSS MUTATED | 41 | 16 | 37 |
| 17Q LOSS WILD-TYPE | 141 | 150 | 116 |
Figure S344. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00161 (Fisher's exact test), Q value = 0.0084
Table S345. Gene #72: '17q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 17Q LOSS MUTATED | 37 | 11 | 22 |
| 17Q LOSS WILD-TYPE | 115 | 111 | 71 |
Figure S345. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.0016
Table S346. Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 17Q LOSS MUTATED | 32 | 13 | 31 | 18 |
| 17Q LOSS WILD-TYPE | 81 | 139 | 123 | 61 |
Figure S346. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S347. Gene #72: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 17Q LOSS MUTATED | 55 | 17 | 22 |
| 17Q LOSS WILD-TYPE | 123 | 172 | 109 |
Figure S347. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00908 (Fisher's exact test), Q value = 0.033
Table S348. Gene #72: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 17Q LOSS MUTATED | 8 | 19 | 46 | 18 |
| 17Q LOSS WILD-TYPE | 81 | 99 | 153 | 51 |
Figure S348. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0434 (Fisher's exact test), Q value = 0.11
Table S349. Gene #72: '17q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 17Q LOSS MUTATED | 10 | 21 | 35 |
| 17Q LOSS WILD-TYPE | 29 | 130 | 109 |
Figure S349. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0384 (Fisher's exact test), Q value = 0.1
Table S350. Gene #75: '19p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 19P LOSS MUTATED | 11 | 13 | 15 | 14 |
| 19P LOSS WILD-TYPE | 31 | 39 | 17 | 14 |
Figure S350. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S351. Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 19P LOSS MUTATED | 47 | 47 | 73 |
| 19P LOSS WILD-TYPE | 135 | 119 | 80 |
Figure S351. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0437 (Fisher's exact test), Q value = 0.11
Table S352. Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 19P LOSS MUTATED | 38 | 38 | 58 | 32 |
| 19P LOSS WILD-TYPE | 75 | 114 | 96 | 47 |
Figure S352. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.062
Table S353. Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 19P LOSS MUTATED | 62 | 50 | 54 |
| 19P LOSS WILD-TYPE | 116 | 139 | 77 |
Figure S353. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00019 (Fisher's exact test), Q value = 0.0016
Table S354. Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 19P LOSS MUTATED | 17 | 39 | 84 | 15 |
| 19P LOSS WILD-TYPE | 72 | 79 | 115 | 54 |
Figure S354. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0414 (Fisher's exact test), Q value = 0.11
Table S355. Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 19Q LOSS MUTATED | 30 | 40 | 42 |
| 19Q LOSS WILD-TYPE | 152 | 126 | 111 |
Figure S355. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0248 (Fisher's exact test), Q value = 0.074
Table S356. Gene #77: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 20P LOSS MUTATED | 16 | 7 | 19 |
| 20P LOSS WILD-TYPE | 166 | 159 | 134 |
Figure S356. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0032 (Fisher's exact test), Q value = 0.015
Table S357. Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 20P LOSS MUTATED | 10 | 4 | 15 |
| 20P LOSS WILD-TYPE | 142 | 118 | 78 |
Figure S357. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0311 (Fisher's exact test), Q value = 0.087
Table S358. Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 20P LOSS MUTATED | 16 | 9 | 17 |
| 20P LOSS WILD-TYPE | 162 | 180 | 114 |
Figure S358. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00203 (Fisher's exact test), Q value = 0.01
Table S359. Gene #78: '20q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 20Q LOSS MUTATED | 13 | 26 | 7 |
| 20Q LOSS WILD-TYPE | 169 | 140 | 146 |
Figure S359. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.0235 (Fisher's exact test), Q value = 0.072
Table S360. Gene #78: '20q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 20Q LOSS MUTATED | 8 | 18 | 7 |
| 20Q LOSS WILD-TYPE | 144 | 104 | 86 |
Figure S360. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00027
Table S361. Gene #78: '20q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 20Q LOSS MUTATED | 3 | 28 | 12 | 3 |
| 20Q LOSS WILD-TYPE | 110 | 124 | 142 | 76 |
Figure S361. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00144 (Fisher's exact test), Q value = 0.0079
Table S362. Gene #78: '20q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 20Q LOSS MUTATED | 9 | 29 | 8 |
| 20Q LOSS WILD-TYPE | 169 | 160 | 123 |
Figure S362. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.01 (Fisher's exact test), Q value = 0.036
Table S363. Gene #78: '20q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 20Q LOSS MUTATED | 14 | 19 | 3 | 7 | 3 |
| 20Q LOSS WILD-TYPE | 107 | 115 | 118 | 55 | 34 |
Figure S363. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S364. Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| 21Q LOSS MUTATED | 69 | 106 | 90 |
| 21Q LOSS WILD-TYPE | 113 | 60 | 63 |
Figure S364. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00543 (Fisher's exact test), Q value = 0.022
Table S365. Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| 21Q LOSS MUTATED | 65 | 76 | 47 |
| 21Q LOSS WILD-TYPE | 87 | 46 | 46 |
Figure S365. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.0384 (Fisher's exact test), Q value = 0.1
Table S366. Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 21Q LOSS MUTATED | 86 | 114 | 64 |
| 21Q LOSS WILD-TYPE | 92 | 75 | 67 |
Figure S366. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0158 (Fisher's exact test), Q value = 0.052
Table S367. Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| 21Q LOSS MUTATED | 72 | 74 | 50 | 32 | 25 |
| 21Q LOSS WILD-TYPE | 49 | 60 | 71 | 30 | 12 |
Figure S367. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00059 (Fisher's exact test), Q value = 0.004
Table S368. Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 21Q LOSS MUTATED | 51 | 64 | 117 | 21 |
| 21Q LOSS WILD-TYPE | 38 | 54 | 82 | 48 |
Figure S368. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0243 (Fisher's exact test), Q value = 0.073
Table S369. Gene #79: '21q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| 21Q LOSS MUTATED | 36 | 63 | 69 |
| 21Q LOSS WILD-TYPE | 53 | 66 | 47 |
Figure S369. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 0.0126 (Fisher's exact test), Q value = 0.044
Table S370. Gene #79: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| 21Q LOSS MUTATED | 22 | 87 | 59 |
| 21Q LOSS WILD-TYPE | 17 | 64 | 85 |
Figure S370. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00907 (Fisher's exact test), Q value = 0.033
Table S371. Gene #80: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 42 | 52 | 32 | 28 |
| 22Q LOSS MUTATED | 7 | 7 | 6 | 13 |
| 22Q LOSS WILD-TYPE | 35 | 45 | 26 | 15 |
Figure S371. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00089
Table S372. Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| 22Q LOSS MUTATED | 22 | 15 | 47 | 14 |
| 22Q LOSS WILD-TYPE | 91 | 137 | 107 | 65 |
Figure S372. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S373. Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| 22Q LOSS MUTATED | 26 | 24 | 48 |
| 22Q LOSS WILD-TYPE | 152 | 165 | 83 |
Figure S373. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.009 (Fisher's exact test), Q value = 0.033
Table S374. Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| 22Q LOSS MUTATED | 10 | 31 | 41 | 7 |
| 22Q LOSS WILD-TYPE | 79 | 87 | 158 | 62 |
Figure S374. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00036
Table S375. Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| XP LOSS MUTATED | 30 | 63 | 53 |
| XP LOSS WILD-TYPE | 152 | 103 | 100 |
Figure S375. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S376. Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| XP LOSS MUTATED | 22 | 50 | 33 |
| XP LOSS WILD-TYPE | 130 | 72 | 60 |
Figure S376. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00254 (Fisher's exact test), Q value = 0.012
Table S377. Gene #81: 'xp loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| XP LOSS MUTATED | 33 | 58 | 41 | 12 |
| XP LOSS WILD-TYPE | 80 | 94 | 113 | 67 |
Figure S377. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.0192 (Fisher's exact test), Q value = 0.061
Table S378. Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 178 | 189 | 131 |
| XP LOSS MUTATED | 47 | 68 | 29 |
| XP LOSS WILD-TYPE | 131 | 121 | 102 |
Figure S378. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #8: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0118 (Fisher's exact test), Q value = 0.042
Table S379. Gene #81: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| XP LOSS MUTATED | 40 | 46 | 21 | 22 | 12 |
| XP LOSS WILD-TYPE | 81 | 88 | 100 | 40 | 25 |
Figure S379. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.00152 (Fisher's exact test), Q value = 0.0081
Table S380. Gene #81: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| XP LOSS MUTATED | 35 | 40 | 57 | 9 |
| XP LOSS WILD-TYPE | 54 | 78 | 142 | 60 |
Figure S380. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 5e-04 (Fisher's exact test), Q value = 0.0036
Table S381. Gene #81: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| XP LOSS MUTATED | 12 | 39 | 43 |
| XP LOSS WILD-TYPE | 77 | 90 | 73 |
Figure S381. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S382. Gene #81: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| XP LOSS MUTATED | 9 | 63 | 22 |
| XP LOSS WILD-TYPE | 30 | 88 | 122 |
Figure S382. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00015
Table S383. Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 182 | 166 | 153 |
| XQ LOSS MUTATED | 20 | 40 | 52 |
| XQ LOSS WILD-TYPE | 162 | 126 | 101 |
Figure S383. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #3: 'CN_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.0012
Table S384. Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 152 | 122 | 93 |
| XQ LOSS MUTATED | 18 | 32 | 32 |
| XQ LOSS WILD-TYPE | 134 | 90 | 61 |
Figure S384. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #4: 'METHLYATION_CNMF'
P value = 0.00808 (Fisher's exact test), Q value = 0.03
Table S385. Gene #82: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 113 | 152 | 154 | 79 |
| XQ LOSS MUTATED | 26 | 36 | 42 | 7 |
| XQ LOSS WILD-TYPE | 87 | 116 | 112 | 72 |
Figure S385. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #7: 'MRNASEQ_CNMF'
P value = 0.00842 (Fisher's exact test), Q value = 0.031
Table S386. Gene #82: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 121 | 134 | 121 | 62 | 37 |
| XQ LOSS MUTATED | 30 | 40 | 15 | 12 | 11 |
| XQ LOSS WILD-TYPE | 91 | 94 | 106 | 50 | 26 |
Figure S386. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_CNMF'
P value = 0.0147 (Fisher's exact test), Q value = 0.05
Table S387. Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 89 | 118 | 199 | 69 |
| XQ LOSS MUTATED | 22 | 28 | 52 | 6 |
| XQ LOSS WILD-TYPE | 67 | 90 | 147 | 63 |
Figure S387. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0046 (Fisher's exact test), Q value = 0.02
Table S388. Gene #82: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 89 | 129 | 116 |
| XQ LOSS MUTATED | 10 | 29 | 35 |
| XQ LOSS WILD-TYPE | 79 | 100 | 81 |
Figure S388. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00027
Table S389. Gene #82: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 39 | 151 | 144 |
| XQ LOSS MUTATED | 8 | 51 | 15 |
| XQ LOSS WILD-TYPE | 31 | 100 | 129 |
Figure S389. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #12: 'MIRSEQ_MATURE_CHIERARCHICAL'
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Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/LUSC-TP/15093662/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/LUSC-TP/15114194/LUSC-TP.transferedmergedcluster.txt
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Number of patients = 501
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Number of significantly arm-level cnvs = 82
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Number of molecular subtypes = 12
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Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.