This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 80 arm-level events and 8 molecular subtypes across 492 patients, 331 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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2p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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2q gain cnv correlated to 'CN_CNMF'.
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3p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4p gain cnv correlated to 'CN_CNMF'.
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5p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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6p gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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6q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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7p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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9q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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11q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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12p gain cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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12q gain cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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13q gain cnv correlated to 'CN_CNMF'.
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14q gain cnv correlated to 'CN_CNMF'.
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15q gain cnv correlated to 'CN_CNMF'.
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16p gain cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16q gain cnv correlated to 'MIRSEQ_CHIERARCHICAL'.
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17p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p gain cnv correlated to 'CN_CNMF'.
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18q gain cnv correlated to 'CN_CNMF'.
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19p gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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19q gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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20p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp gain cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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xq gain cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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1p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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2p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3p loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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3q loss cnv correlated to 'MIRSEQ_CHIERARCHICAL'.
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4p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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5q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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9p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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9q loss cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'CN_CNMF'.
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11q loss cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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12p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q loss cnv correlated to 'CN_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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13q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q loss cnv correlated to 'CN_CNMF'.
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15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p loss cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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18p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'CN_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p loss cnv correlated to 'CN_CNMF'.
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20q loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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21q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 80 arm-level events and 8 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 331 significant findings detected.
|
Clinical Features |
CN CNMF |
METHLYATION CNMF |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 3p gain | 40 (8%) | 452 |
1e-05 (0.000119) |
0.0103 (0.0305) |
0.00472 (0.0162) |
0.00036 (0.00222) |
0.021 (0.0514) |
0.00531 (0.0176) |
0.00361 (0.0134) |
0.00027 (0.00175) |
| 3q gain | 54 (11%) | 438 |
1e-05 (0.000119) |
0.0076 (0.0234) |
0.00123 (0.00592) |
0.00129 (0.00607) |
0.00433 (0.0151) |
0.00377 (0.0138) |
0.0147 (0.039) |
2e-05 (0.000194) |
| 7p gain | 102 (21%) | 390 |
1e-05 (0.000119) |
1e-05 (0.000119) |
1e-05 (0.000119) |
2e-05 (0.000194) |
0.0186 (0.0476) |
1e-05 (0.000119) |
0.0003 (0.00192) |
0.0017 (0.0075) |
| 7q gain | 95 (19%) | 397 |
1e-05 (0.000119) |
1e-05 (0.000119) |
1e-05 (0.000119) |
7e-05 (0.00056) |
0.0243 (0.0579) |
4e-05 (0.000351) |
0.0004 (0.00242) |
0.00524 (0.0175) |
| 8q gain | 124 (25%) | 368 |
1e-05 (0.000119) |
1e-05 (0.000119) |
3e-05 (0.000274) |
3e-05 (0.000274) |
0.00046 (0.00268) |
1e-05 (0.000119) |
2e-05 (0.000194) |
2e-05 (0.000194) |
| 20p gain | 26 (5%) | 466 |
1e-05 (0.000119) |
0.0208 (0.0513) |
0.0223 (0.0537) |
0.0364 (0.0762) |
0.00213 (0.00885) |
0.00394 (0.0142) |
0.0296 (0.0673) |
0.00454 (0.0157) |
| 21q gain | 21 (4%) | 471 |
1e-05 (0.000119) |
0.0386 (0.0789) |
0.00156 (0.00717) |
0.0264 (0.062) |
0.0137 (0.0376) |
0.00347 (0.0131) |
0.0124 (0.0349) |
0.0292 (0.0669) |
| 1p loss | 22 (4%) | 470 |
1e-05 (0.000119) |
0.00057 (0.00317) |
0.00122 (0.00592) |
0.00019 (0.00131) |
0.0251 (0.0594) |
0.00364 (0.0135) |
0.0196 (0.0496) |
0.0132 (0.0367) |
| 4p loss | 24 (5%) | 468 |
1e-05 (0.000119) |
0.0189 (0.0481) |
0.00375 (0.0138) |
0.0295 (0.0673) |
0.00152 (0.00705) |
0.00258 (0.0105) |
4e-05 (0.000351) |
7e-05 (0.00056) |
| 6q loss | 40 (8%) | 452 |
1e-05 (0.000119) |
0.0358 (0.0761) |
0.00036 (0.00222) |
0.00124 (0.00592) |
0.013 (0.0362) |
0.0477 (0.0934) |
0.00407 (0.0144) |
0.00207 (0.00866) |
| 10q loss | 43 (9%) | 449 |
1e-05 (0.000119) |
0.00086 (0.00451) |
0.00201 (0.00846) |
0.00051 (0.00291) |
0.0391 (0.0792) |
0.00125 (0.00593) |
0.00174 (0.00757) |
7e-05 (0.00056) |
| 15q loss | 36 (7%) | 456 |
1e-05 (0.000119) |
0.00166 (0.00738) |
0.00068 (0.00369) |
0.00648 (0.0205) |
0.0001 (0.000744) |
0.00751 (0.0232) |
0.00116 (0.00567) |
0.00013 (0.000945) |
| 18q loss | 101 (21%) | 391 |
1e-05 (0.000119) |
0.00629 (0.0202) |
0.00339 (0.013) |
0.0223 (0.0537) |
0.0068 (0.0214) |
0.0034 (0.013) |
0.0154 (0.0405) |
1e-05 (0.000119) |
| 8p gain | 71 (14%) | 421 |
1e-05 (0.000119) |
1e-05 (0.000119) |
7e-05 (0.00056) |
0.00046 (0.00268) |
0.125 (0.184) |
0.00512 (0.0172) |
0.00196 (0.00831) |
0.00231 (0.00948) |
| 6p loss | 25 (5%) | 467 |
1e-05 (0.000119) |
0.0147 (0.039) |
0.00032 (0.00203) |
0.00298 (0.0117) |
0.0581 (0.108) |
0.0316 (0.0696) |
0.0141 (0.0383) |
0.00402 (0.0143) |
| 10p loss | 41 (8%) | 451 |
1e-05 (0.000119) |
0.00011 (0.000809) |
0.00026 (0.0017) |
0.0001 (0.000744) |
0.0842 (0.143) |
5e-05 (0.000427) |
0.0113 (0.0324) |
5e-05 (0.000427) |
| 16q loss | 107 (22%) | 385 |
1e-05 (0.000119) |
0.00069 (0.00371) |
0.0306 (0.0688) |
0.0304 (0.0688) |
0.0839 (0.143) |
0.00054 (0.00306) |
0.00422 (0.0148) |
8e-05 (0.000617) |
| 17p loss | 76 (15%) | 416 |
1e-05 (0.000119) |
0.00157 (0.00717) |
0.00014 (0.000985) |
0.00171 (0.0075) |
0.0978 (0.157) |
0.0318 (0.0696) |
0.0225 (0.0541) |
8e-05 (0.000617) |
| 17q loss | 20 (4%) | 472 |
1e-05 (0.000119) |
0.0101 (0.0304) |
0.00092 (0.00479) |
0.0357 (0.0761) |
0.0124 (0.0349) |
0.0452 (0.0895) |
0.0306 (0.0688) |
0.144 (0.206) |
| 18p loss | 68 (14%) | 424 |
1e-05 (0.000119) |
0.005 (0.0169) |
0.00325 (0.0126) |
0.0491 (0.0953) |
0.0584 (0.108) |
0.0299 (0.0679) |
0.0103 (0.0305) |
0.00567 (0.0184) |
| xp loss | 39 (8%) | 453 |
1e-05 (0.000119) |
2e-05 (0.000194) |
0.00049 (0.00283) |
4e-05 (0.000351) |
1e-05 (0.000119) |
0.0355 (0.0761) |
0.00556 (0.0182) |
0.0984 (0.157) |
| xq loss | 39 (8%) | 453 |
1e-05 (0.000119) |
2e-05 (0.000194) |
0.00041 (0.00245) |
6e-05 (0.000505) |
1e-05 (0.000119) |
0.0363 (0.0762) |
0.00548 (0.0181) |
0.0982 (0.157) |
| 5p gain | 23 (5%) | 469 |
1e-05 (0.000119) |
0.0588 (0.109) |
0.00926 (0.0278) |
0.0612 (0.112) |
0.0014 (0.00654) |
0.00163 (0.0073) |
0.00193 (0.00823) |
0.00395 (0.0142) |
| 5q loss | 22 (4%) | 470 |
1e-05 (0.000119) |
0.00293 (0.0116) |
0.0124 (0.0349) |
0.00216 (0.00892) |
0.0579 (0.108) |
0.00111 (0.00546) |
0.109 (0.164) |
0.027 (0.0627) |
| 8p loss | 168 (34%) | 324 |
1e-05 (0.000119) |
1e-05 (0.000119) |
1e-05 (0.000119) |
1e-05 (0.000119) |
0.00044 (0.00261) |
0.0793 (0.136) |
0.0578 (0.108) |
0.0309 (0.0688) |
| 9q gain | 50 (10%) | 442 |
1e-05 (0.000119) |
0.117 (0.173) |
0.0148 (0.0392) |
0.196 (0.258) |
0.358 (0.424) |
0.0106 (0.0308) |
0.00707 (0.022) |
0.0136 (0.0375) |
| 10p gain | 15 (3%) | 477 |
8e-05 (0.000617) |
0.0348 (0.0751) |
0.103 (0.159) |
0.0334 (0.0727) |
0.575 (0.625) |
0.0135 (0.0375) |
0.173 (0.236) |
0.00082 (0.00434) |
| 17p gain | 8 (2%) | 484 |
0.0145 (0.039) |
0.912 (0.928) |
0.0491 (0.0953) |
0.665 (0.702) |
0.0212 (0.0517) |
0.0162 (0.0422) |
0.608 (0.652) |
0.00361 (0.0134) |
| 20q gain | 28 (6%) | 464 |
1e-05 (0.000119) |
0.0199 (0.0502) |
0.0565 (0.107) |
0.126 (0.185) |
0.0112 (0.0323) |
0.00787 (0.0241) |
0.101 (0.158) |
0.00896 (0.027) |
| 2q loss | 18 (4%) | 474 |
0.00014 (0.000985) |
0.0205 (0.0509) |
0.724 (0.755) |
0.484 (0.552) |
0.127 (0.186) |
0.0349 (0.0751) |
0.00882 (0.0269) |
0.001 (0.00504) |
| 4q loss | 17 (3%) | 475 |
1e-05 (0.000119) |
0.155 (0.218) |
0.00638 (0.0204) |
0.103 (0.159) |
0.201 (0.263) |
0.0466 (0.0919) |
0.0144 (0.0388) |
0.00521 (0.0175) |
| 12p loss | 48 (10%) | 444 |
1e-05 (0.000119) |
0.296 (0.365) |
0.0485 (0.0947) |
0.422 (0.489) |
0.455 (0.524) |
0.0164 (0.0428) |
0.00684 (0.0215) |
0.00272 (0.0109) |
| 22q loss | 47 (10%) | 445 |
1e-05 (0.000119) |
0.21 (0.273) |
0.0187 (0.0476) |
0.0475 (0.0933) |
0.0688 (0.122) |
0.0278 (0.0643) |
0.149 (0.211) |
0.00024 (0.0016) |
| 1p gain | 16 (3%) | 476 |
2e-05 (0.000194) |
0.203 (0.265) |
0.0107 (0.0309) |
0.00062 (0.00342) |
0.309 (0.377) |
0.0413 (0.0828) |
0.848 (0.872) |
0.177 (0.239) |
| 1q gain | 26 (5%) | 466 |
1e-05 (0.000119) |
0.142 (0.203) |
0.00014 (0.000985) |
0.00056 (0.00314) |
0.0975 (0.157) |
0.0324 (0.0708) |
0.503 (0.566) |
0.194 (0.257) |
| 16p gain | 31 (6%) | 461 |
1e-05 (0.000119) |
0.264 (0.331) |
0.0697 (0.123) |
0.318 (0.386) |
0.155 (0.218) |
0.00398 (0.0142) |
0.0263 (0.0618) |
0.0124 (0.0349) |
| 2p loss | 16 (3%) | 476 |
9e-05 (0.000686) |
0.00486 (0.0165) |
0.481 (0.549) |
0.354 (0.421) |
0.133 (0.193) |
0.0874 (0.146) |
0.00389 (0.0141) |
0.00345 (0.0131) |
| 5p loss | 12 (2%) | 480 |
2e-05 (0.000194) |
0.173 (0.236) |
0.0376 (0.0782) |
0.00562 (0.0184) |
0.866 (0.886) |
0.00319 (0.0124) |
0.51 (0.567) |
0.104 (0.16) |
| 8q loss | 24 (5%) | 468 |
0.0289 (0.0666) |
0.001 (0.00504) |
0.0105 (0.0307) |
0.0249 (0.0591) |
0.101 (0.159) |
0.992 (1.00) |
0.219 (0.284) |
0.246 (0.312) |
| 13q loss | 77 (16%) | 415 |
1e-05 (0.000119) |
0.33 (0.396) |
0.0419 (0.0839) |
0.0656 (0.118) |
0.184 (0.245) |
0.0408 (0.0822) |
0.225 (0.289) |
0.00016 (0.00111) |
| 2p gain | 10 (2%) | 482 |
0.00095 (0.00486) |
0.0755 (0.131) |
0.00706 (0.022) |
0.143 (0.204) |
0.114 (0.169) |
0.0359 (0.0761) |
0.168 (0.23) |
0.188 (0.249) |
| 10q gain | 14 (3%) | 478 |
0.00021 (0.00141) |
0.0581 (0.108) |
0.131 (0.191) |
0.0316 (0.0696) |
0.588 (0.636) |
0.0883 (0.146) |
0.27 (0.335) |
0.00192 (0.00823) |
| 11p gain | 26 (5%) | 466 |
1e-05 (0.000119) |
0.0537 (0.103) |
0.0923 (0.152) |
0.0142 (0.0386) |
0.598 (0.646) |
0.0539 (0.103) |
0.0356 (0.0761) |
0.177 (0.239) |
| 11q gain | 29 (6%) | 463 |
1e-05 (0.000119) |
0.0727 (0.127) |
0.0309 (0.0688) |
0.0381 (0.0787) |
0.689 (0.723) |
0.0502 (0.0967) |
0.084 (0.143) |
0.123 (0.181) |
| 12p gain | 14 (3%) | 478 |
3e-05 (0.000274) |
0.183 (0.245) |
0.0875 (0.146) |
0.115 (0.171) |
0.361 (0.427) |
0.00094 (0.00485) |
0.0233 (0.0557) |
0.206 (0.269) |
| 12q gain | 17 (3%) | 475 |
0.00039 (0.00238) |
0.0828 (0.141) |
0.198 (0.26) |
0.112 (0.168) |
0.784 (0.813) |
0.0203 (0.0506) |
0.0154 (0.0405) |
0.0964 (0.156) |
| 17q gain | 11 (2%) | 481 |
0.00035 (0.0022) |
0.799 (0.826) |
0.0166 (0.0429) |
0.216 (0.28) |
0.0908 (0.15) |
0.11 (0.166) |
0.472 (0.541) |
0.00067 (0.00366) |
| xp gain | 7 (1%) | 485 |
0.00082 (0.00434) |
0.0648 (0.117) |
0.101 (0.158) |
0.0928 (0.153) |
0.51 (0.567) |
0.045 (0.0895) |
0.00615 (0.0199) |
0.0868 (0.145) |
| xq gain | 7 (1%) | 485 |
0.00106 (0.00526) |
0.0645 (0.116) |
0.099 (0.158) |
0.0942 (0.155) |
0.508 (0.567) |
0.0456 (0.09) |
0.0064 (0.0204) |
0.0864 (0.145) |
| 9p loss | 21 (4%) | 471 |
1e-05 (0.000119) |
0.283 (0.351) |
0.00415 (0.0146) |
0.0211 (0.0514) |
0.267 (0.333) |
0.245 (0.312) |
0.107 (0.163) |
0.0619 (0.113) |
| 12q loss | 20 (4%) | 472 |
3e-05 (0.000274) |
0.179 (0.241) |
0.251 (0.318) |
0.265 (0.331) |
1 (1.00) |
0.0493 (0.0953) |
0.0671 (0.119) |
0.00892 (0.027) |
| 19p loss | 17 (3%) | 475 |
0.00021 (0.00141) |
0.0558 (0.106) |
0.307 (0.376) |
0.158 (0.219) |
0.134 (0.195) |
0.158 (0.219) |
0.00292 (0.0116) |
0.0104 (0.0307) |
| 19q loss | 17 (3%) | 475 |
0.00025 (0.00165) |
0.0561 (0.106) |
0.304 (0.372) |
0.16 (0.219) |
0.133 (0.193) |
0.157 (0.219) |
0.00294 (0.0116) |
0.0104 (0.0306) |
| 21q loss | 24 (5%) | 468 |
2e-05 (0.000194) |
0.0667 (0.119) |
0.00361 (0.0134) |
0.323 (0.39) |
0.572 (0.623) |
0.103 (0.159) |
0.422 (0.489) |
0.0404 (0.0815) |
| 5q gain | 12 (2%) | 480 |
2e-05 (0.000194) |
0.173 (0.236) |
0.0363 (0.0762) |
0.23 (0.293) |
0.373 (0.439) |
0.158 (0.219) |
0.124 (0.182) |
0.325 (0.391) |
| 6p gain | 10 (2%) | 482 |
0.00158 (0.00717) |
0.157 (0.219) |
0.139 (0.2) |
0.268 (0.333) |
0.672 (0.708) |
0.106 (0.162) |
0.017 (0.0436) |
0.0746 (0.13) |
| 6q gain | 6 (1%) | 486 |
0.0206 (0.0509) |
0.791 (0.82) |
0.103 (0.159) |
0.579 (0.628) |
0.196 (0.258) |
0.0391 (0.0792) |
0.27 (0.335) |
0.564 (0.616) |
| 9p gain | 34 (7%) | 458 |
1e-05 (0.000119) |
0.1 (0.158) |
0.0785 (0.135) |
0.0955 (0.156) |
0.486 (0.553) |
0.111 (0.167) |
0.0166 (0.0429) |
0.179 (0.241) |
| 19p gain | 12 (2%) | 480 |
1e-05 (0.000119) |
0.159 (0.219) |
0.0365 (0.0762) |
0.343 (0.409) |
0.14 (0.2) |
0.0858 (0.144) |
0.515 (0.571) |
0.119 (0.176) |
| 19q gain | 12 (2%) | 480 |
1e-05 (0.000119) |
0.104 (0.16) |
0.0391 (0.0792) |
0.367 (0.434) |
0.219 (0.284) |
0.0609 (0.112) |
0.508 (0.567) |
0.154 (0.218) |
| 1q loss | 6 (1%) | 486 |
0.0206 (0.0509) |
0.152 (0.216) |
0.0425 (0.0847) |
0.0962 (0.156) |
0.1 (0.158) |
0.102 (0.159) |
0.0516 (0.099) |
0.394 (0.462) |
| 3p loss | 9 (2%) | 483 |
0.0336 (0.073) |
0.315 (0.384) |
0.105 (0.16) |
0.0385 (0.0789) |
0.104 (0.159) |
0.412 (0.48) |
0.0509 (0.0978) |
0.196 (0.258) |
| 9q loss | 10 (2%) | 482 |
0.00163 (0.0073) |
0.342 (0.408) |
0.264 (0.331) |
0.228 (0.292) |
0.616 (0.658) |
0.548 (0.605) |
0.52 (0.576) |
0.0364 (0.0762) |
| 11q loss | 5 (1%) | 487 |
0.0137 (0.0376) |
0.0704 (0.124) |
0.0614 (0.112) |
0.3 (0.369) |
0.632 (0.675) |
0.187 (0.249) |
0.0218 (0.0529) |
0.291 (0.36) |
| 16p loss | 32 (7%) | 460 |
0.00175 (0.00757) |
0.334 (0.4) |
0.492 (0.555) |
0.38 (0.447) |
0.646 (0.687) |
0.319 (0.387) |
0.223 (0.287) |
0.0316 (0.0696) |
| 20q loss | 9 (2%) | 483 |
0.0271 (0.0629) |
0.0791 (0.136) |
0.0956 (0.156) |
0.0381 (0.0787) |
0.0734 (0.128) |
0.0607 (0.112) |
1 (1.00) |
0.504 (0.566) |
| 2q gain | 7 (1%) | 485 |
0.00103 (0.00515) |
0.465 (0.534) |
0.101 (0.158) |
0.553 (0.608) |
0.508 (0.567) |
0.0623 (0.113) |
0.177 (0.239) |
0.159 (0.219) |
| 4p gain | 9 (2%) | 483 |
0.0269 (0.0627) |
0.845 (0.871) |
0.489 (0.553) |
0.768 (0.799) |
0.915 (0.929) |
0.415 (0.483) |
0.605 (0.65) |
0.572 (0.623) |
| 13q gain | 8 (2%) | 484 |
0.0144 (0.0389) |
0.137 (0.198) |
0.606 (0.651) |
0.662 (0.701) |
0.821 (0.848) |
0.563 (0.616) |
0.741 (0.772) |
0.865 (0.886) |
| 14q gain | 10 (2%) | 482 |
2e-05 (0.000194) |
0.159 (0.219) |
0.0856 (0.144) |
0.226 (0.289) |
0.113 (0.169) |
0.256 (0.323) |
0.489 (0.553) |
0.466 (0.534) |
| 15q gain | 6 (1%) | 486 |
0.0201 (0.0504) |
1 (1.00) |
0.877 (0.897) |
0.665 (0.702) |
0.777 (0.807) |
0.182 (0.244) |
0.706 (0.739) |
0.321 (0.389) |
| 16q gain | 8 (2%) | 484 |
0.0849 (0.143) |
0.5 (0.564) |
0.604 (0.65) |
0.904 (0.922) |
0.102 (0.159) |
0.0124 (0.0349) |
0.647 (0.687) |
0.543 (0.6) |
| 18p gain | 18 (4%) | 474 |
1e-05 (0.000119) |
0.356 (0.423) |
0.139 (0.2) |
0.508 (0.567) |
0.688 (0.723) |
0.609 (0.652) |
0.723 (0.755) |
0.45 (0.519) |
| 18q gain | 9 (2%) | 483 |
0.00473 (0.0162) |
1 (1.00) |
0.106 (0.162) |
0.909 (0.926) |
0.64 (0.682) |
0.444 (0.514) |
0.446 (0.515) |
0.665 (0.702) |
| 3q loss | 5 (1%) | 487 |
0.304 (0.372) |
1 (1.00) |
0.328 (0.394) |
0.249 (0.316) |
0.152 (0.216) |
0.0317 (0.0696) |
||
| 11p loss | 8 (2%) | 484 |
0.0024 (0.00978) |
0.0809 (0.139) |
0.265 (0.331) |
0.117 (0.173) |
0.322 (0.39) |
0.26 (0.328) |
0.113 (0.169) |
0.102 (0.159) |
| 14q loss | 25 (5%) | 467 |
2e-05 (0.000194) |
0.0576 (0.108) |
0.0758 (0.131) |
0.0981 (0.157) |
0.405 (0.474) |
0.0641 (0.116) |
0.0988 (0.158) |
0.0669 (0.119) |
| 20p loss | 19 (4%) | 473 |
0.0383 (0.0788) |
0.0635 (0.115) |
0.223 (0.287) |
0.184 (0.245) |
0.489 (0.553) |
0.183 (0.245) |
1 (1.00) |
0.583 (0.631) |
| 4q gain | 10 (2%) | 482 |
0.0729 (0.128) |
0.486 (0.553) |
1 (1.00) |
0.555 (0.608) |
0.854 (0.877) |
0.177 (0.239) |
0.154 (0.218) |
0.0696 (0.123) |
| 22q gain | 4 (1%) | 488 |
0.0955 (0.156) |
0.551 (0.607) |
0.555 (0.608) |
0.222 (0.286) |
0.325 (0.391) |
0.406 (0.474) |
0.404 (0.474) |
0.159 (0.219) |
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S1. Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 1P GAIN MUTATED | 2 | 14 | 0 |
| 1P GAIN WILD-TYPE | 271 | 120 | 85 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.031
Table S2. Gene #1: '1p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 1P GAIN MUTATED | 0 | 8 | 8 |
| 1P GAIN WILD-TYPE | 146 | 163 | 166 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00062 (Fisher's exact test), Q value = 0.0034
Table S3. Gene #1: '1p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 1P GAIN MUTATED | 0 | 13 | 3 |
| 1P GAIN WILD-TYPE | 171 | 192 | 112 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0413 (Fisher's exact test), Q value = 0.083
Table S4. Gene #1: '1p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 1P GAIN MUTATED | 1 | 4 | 1 | 9 | 1 |
| 1P GAIN WILD-TYPE | 146 | 94 | 58 | 119 | 55 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S5. Gene #2: '1q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 1Q GAIN MUTATED | 5 | 21 | 0 |
| 1Q GAIN WILD-TYPE | 268 | 113 | 85 |
Figure S5. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00098
Table S6. Gene #2: '1q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 1Q GAIN MUTATED | 0 | 10 | 16 |
| 1Q GAIN WILD-TYPE | 146 | 161 | 158 |
Figure S6. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00056 (Fisher's exact test), Q value = 0.0031
Table S7. Gene #2: '1q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 1Q GAIN MUTATED | 1 | 15 | 10 |
| 1Q GAIN WILD-TYPE | 170 | 190 | 105 |
Figure S7. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0324 (Fisher's exact test), Q value = 0.071
Table S8. Gene #2: '1q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 1Q GAIN MUTATED | 4 | 4 | 3 | 14 | 1 |
| 1Q GAIN WILD-TYPE | 143 | 94 | 56 | 114 | 55 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00095 (Fisher's exact test), Q value = 0.0049
Table S9. Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 2P GAIN MUTATED | 1 | 8 | 1 |
| 2P GAIN WILD-TYPE | 272 | 126 | 84 |
Figure S9. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00706 (Fisher's exact test), Q value = 0.022
Table S10. Gene #3: '2p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 2P GAIN MUTATED | 0 | 8 | 2 |
| 2P GAIN WILD-TYPE | 146 | 163 | 172 |
Figure S10. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0359 (Fisher's exact test), Q value = 0.076
Table S11. Gene #3: '2p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 2P GAIN MUTATED | 0 | 4 | 0 | 5 | 1 |
| 2P GAIN WILD-TYPE | 147 | 94 | 59 | 123 | 55 |
Figure S11. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00103 (Fisher's exact test), Q value = 0.0051
Table S12. Gene #4: '2q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 2Q GAIN MUTATED | 0 | 6 | 1 |
| 2Q GAIN WILD-TYPE | 273 | 128 | 84 |
Figure S12. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S13. Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 3P GAIN MUTATED | 3 | 32 | 5 |
| 3P GAIN WILD-TYPE | 270 | 102 | 80 |
Figure S13. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0103 (Fisher's exact test), Q value = 0.03
Table S14. Gene #5: '3p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 3P GAIN MUTATED | 7 | 22 | 11 |
| 3P GAIN WILD-TYPE | 153 | 143 | 156 |
Figure S14. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00472 (Fisher's exact test), Q value = 0.016
Table S15. Gene #5: '3p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 3P GAIN MUTATED | 5 | 23 | 12 |
| 3P GAIN WILD-TYPE | 141 | 148 | 162 |
Figure S15. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0022
Table S16. Gene #5: '3p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 3P GAIN MUTATED | 4 | 27 | 9 |
| 3P GAIN WILD-TYPE | 167 | 178 | 106 |
Figure S16. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.021 (Fisher's exact test), Q value = 0.051
Table S17. Gene #5: '3p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 3P GAIN MUTATED | 8 | 8 | 23 |
| 3P GAIN WILD-TYPE | 150 | 139 | 160 |
Figure S17. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00531 (Fisher's exact test), Q value = 0.018
Table S18. Gene #5: '3p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 3P GAIN MUTATED | 7 | 6 | 2 | 21 | 3 |
| 3P GAIN WILD-TYPE | 140 | 92 | 57 | 107 | 53 |
Figure S18. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00361 (Fisher's exact test), Q value = 0.013
Table S19. Gene #5: '3p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 3P GAIN MUTATED | 0 | 15 | 3 | 6 |
| 3P GAIN WILD-TYPE | 62 | 91 | 57 | 84 |
Figure S19. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0017
Table S20. Gene #5: '3p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 3P GAIN MUTATED | 2 | 2 | 11 | 7 | 0 | 2 |
| 3P GAIN WILD-TYPE | 68 | 39 | 29 | 75 | 25 | 58 |
Figure S20. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S21. Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 3Q GAIN MUTATED | 9 | 37 | 8 |
| 3Q GAIN WILD-TYPE | 264 | 97 | 77 |
Figure S21. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0076 (Fisher's exact test), Q value = 0.023
Table S22. Gene #6: '3q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 3Q GAIN MUTATED | 9 | 27 | 18 |
| 3Q GAIN WILD-TYPE | 151 | 138 | 149 |
Figure S22. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00123 (Fisher's exact test), Q value = 0.0059
Table S23. Gene #6: '3q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 3Q GAIN MUTATED | 6 | 28 | 20 |
| 3Q GAIN WILD-TYPE | 140 | 143 | 154 |
Figure S23. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00129 (Fisher's exact test), Q value = 0.0061
Table S24. Gene #6: '3q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 3Q GAIN MUTATED | 8 | 33 | 13 |
| 3Q GAIN WILD-TYPE | 163 | 172 | 102 |
Figure S24. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00433 (Fisher's exact test), Q value = 0.015
Table S25. Gene #6: '3q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 3Q GAIN MUTATED | 12 | 10 | 31 |
| 3Q GAIN WILD-TYPE | 146 | 137 | 152 |
Figure S25. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00377 (Fisher's exact test), Q value = 0.014
Table S26. Gene #6: '3q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 3Q GAIN MUTATED | 10 | 10 | 4 | 26 | 3 |
| 3Q GAIN WILD-TYPE | 137 | 88 | 55 | 102 | 53 |
Figure S26. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0147 (Fisher's exact test), Q value = 0.039
Table S27. Gene #6: '3q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 3Q GAIN MUTATED | 1 | 17 | 6 | 7 |
| 3Q GAIN WILD-TYPE | 61 | 89 | 54 | 83 |
Figure S27. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S28. Gene #6: '3q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 3Q GAIN MUTATED | 2 | 3 | 14 | 9 | 1 | 2 |
| 3Q GAIN WILD-TYPE | 68 | 38 | 26 | 73 | 24 | 58 |
Figure S28. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0269 (Fisher's exact test), Q value = 0.063
Table S29. Gene #7: '4p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 4P GAIN MUTATED | 2 | 6 | 1 |
| 4P GAIN WILD-TYPE | 271 | 128 | 84 |
Figure S29. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S30. Gene #9: '5p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 5P GAIN MUTATED | 2 | 21 | 0 |
| 5P GAIN WILD-TYPE | 271 | 113 | 85 |
Figure S30. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00926 (Fisher's exact test), Q value = 0.028
Table S31. Gene #9: '5p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 5P GAIN MUTATED | 1 | 10 | 12 |
| 5P GAIN WILD-TYPE | 145 | 161 | 162 |
Figure S31. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0014 (Fisher's exact test), Q value = 0.0065
Table S32. Gene #9: '5p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 5P GAIN MUTATED | 4 | 2 | 17 |
| 5P GAIN WILD-TYPE | 154 | 145 | 166 |
Figure S32. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00163 (Fisher's exact test), Q value = 0.0073
Table S33. Gene #9: '5p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 5P GAIN MUTATED | 4 | 3 | 0 | 15 | 1 |
| 5P GAIN WILD-TYPE | 143 | 95 | 59 | 113 | 55 |
Figure S33. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00193 (Fisher's exact test), Q value = 0.0082
Table S34. Gene #9: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 5P GAIN MUTATED | 1 | 12 | 0 | 2 |
| 5P GAIN WILD-TYPE | 61 | 94 | 60 | 88 |
Figure S34. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00395 (Fisher's exact test), Q value = 0.014
Table S35. Gene #9: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 5P GAIN MUTATED | 2 | 0 | 5 | 8 | 0 | 0 |
| 5P GAIN WILD-TYPE | 68 | 41 | 35 | 74 | 25 | 60 |
Figure S35. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S36. Gene #10: '5q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 5Q GAIN MUTATED | 1 | 11 | 0 |
| 5Q GAIN WILD-TYPE | 272 | 123 | 85 |
Figure S36. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0363 (Fisher's exact test), Q value = 0.076
Table S37. Gene #10: '5q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 5Q GAIN MUTATED | 0 | 5 | 7 |
| 5Q GAIN WILD-TYPE | 146 | 166 | 167 |
Figure S37. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00158 (Fisher's exact test), Q value = 0.0072
Table S38. Gene #11: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 6P GAIN MUTATED | 2 | 8 | 0 |
| 6P GAIN WILD-TYPE | 271 | 126 | 85 |
Figure S38. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.017 (Fisher's exact test), Q value = 0.044
Table S39. Gene #11: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 6P GAIN MUTATED | 0 | 7 | 0 | 1 |
| 6P GAIN WILD-TYPE | 62 | 99 | 60 | 89 |
Figure S39. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0206 (Fisher's exact test), Q value = 0.051
Table S40. Gene #12: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 6Q GAIN MUTATED | 1 | 5 | 0 |
| 6Q GAIN WILD-TYPE | 272 | 129 | 85 |
Figure S40. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0391 (Fisher's exact test), Q value = 0.079
Table S41. Gene #12: '6q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 6Q GAIN MUTATED | 0 | 1 | 0 | 5 | 0 |
| 6Q GAIN WILD-TYPE | 147 | 97 | 59 | 123 | 56 |
Figure S41. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S42. Gene #13: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 7P GAIN MUTATED | 13 | 67 | 22 |
| 7P GAIN WILD-TYPE | 260 | 67 | 63 |
Figure S42. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S43. Gene #13: '7p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 7P GAIN MUTATED | 14 | 60 | 28 |
| 7P GAIN WILD-TYPE | 146 | 105 | 139 |
Figure S43. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S44. Gene #13: '7p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 7P GAIN MUTATED | 10 | 64 | 28 |
| 7P GAIN WILD-TYPE | 136 | 107 | 146 |
Figure S44. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S45. Gene #13: '7p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 7P GAIN MUTATED | 21 | 64 | 17 |
| 7P GAIN WILD-TYPE | 150 | 141 | 98 |
Figure S45. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0186 (Fisher's exact test), Q value = 0.048
Table S46. Gene #13: '7p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 7P GAIN MUTATED | 22 | 31 | 48 |
| 7P GAIN WILD-TYPE | 136 | 116 | 135 |
Figure S46. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S47. Gene #13: '7p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 7P GAIN MUTATED | 16 | 28 | 15 | 38 | 4 |
| 7P GAIN WILD-TYPE | 131 | 70 | 44 | 90 | 52 |
Figure S47. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-04 (Fisher's exact test), Q value = 0.0019
Table S48. Gene #13: '7p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 7P GAIN MUTATED | 4 | 36 | 11 | 18 |
| 7P GAIN WILD-TYPE | 58 | 70 | 49 | 72 |
Figure S48. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0017 (Fisher's exact test), Q value = 0.0075
Table S49. Gene #13: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 7P GAIN MUTATED | 6 | 12 | 13 | 25 | 2 | 11 |
| 7P GAIN WILD-TYPE | 64 | 29 | 27 | 57 | 23 | 49 |
Figure S49. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S50. Gene #14: '7q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 7Q GAIN MUTATED | 13 | 61 | 21 |
| 7Q GAIN WILD-TYPE | 260 | 73 | 64 |
Figure S50. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S51. Gene #14: '7q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 7Q GAIN MUTATED | 11 | 58 | 26 |
| 7Q GAIN WILD-TYPE | 149 | 107 | 141 |
Figure S51. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S52. Gene #14: '7q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 7Q GAIN MUTATED | 10 | 59 | 26 |
| 7Q GAIN WILD-TYPE | 136 | 112 | 148 |
Figure S52. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00056
Table S53. Gene #14: '7q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 7Q GAIN MUTATED | 20 | 59 | 16 |
| 7Q GAIN WILD-TYPE | 151 | 146 | 99 |
Figure S53. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0243 (Fisher's exact test), Q value = 0.058
Table S54. Gene #14: '7q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 7Q GAIN MUTATED | 20 | 30 | 44 |
| 7Q GAIN WILD-TYPE | 138 | 117 | 139 |
Figure S54. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00035
Table S55. Gene #14: '7q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 7Q GAIN MUTATED | 14 | 27 | 14 | 35 | 4 |
| 7Q GAIN WILD-TYPE | 133 | 71 | 45 | 93 | 52 |
Figure S55. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-04 (Fisher's exact test), Q value = 0.0024
Table S56. Gene #14: '7q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 7Q GAIN MUTATED | 4 | 35 | 11 | 16 |
| 7Q GAIN WILD-TYPE | 58 | 71 | 49 | 74 |
Figure S56. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00524 (Fisher's exact test), Q value = 0.017
Table S57. Gene #14: '7q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 7Q GAIN MUTATED | 6 | 11 | 12 | 24 | 2 | 11 |
| 7Q GAIN WILD-TYPE | 64 | 30 | 28 | 58 | 23 | 49 |
Figure S57. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S58. Gene #15: '8p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 8P GAIN MUTATED | 13 | 49 | 9 |
| 8P GAIN WILD-TYPE | 260 | 85 | 76 |
Figure S58. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S59. Gene #15: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 8P GAIN MUTATED | 10 | 47 | 14 |
| 8P GAIN WILD-TYPE | 150 | 118 | 153 |
Figure S59. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00056
Table S60. Gene #15: '8p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 8P GAIN MUTATED | 13 | 42 | 16 |
| 8P GAIN WILD-TYPE | 133 | 129 | 158 |
Figure S60. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00046 (Fisher's exact test), Q value = 0.0027
Table S61. Gene #15: '8p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 8P GAIN MUTATED | 15 | 45 | 11 |
| 8P GAIN WILD-TYPE | 156 | 160 | 104 |
Figure S61. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00512 (Fisher's exact test), Q value = 0.017
Table S62. Gene #15: '8p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 8P GAIN MUTATED | 11 | 15 | 10 | 29 | 5 |
| 8P GAIN WILD-TYPE | 136 | 83 | 49 | 99 | 51 |
Figure S62. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00196 (Fisher's exact test), Q value = 0.0083
Table S63. Gene #15: '8p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 8P GAIN MUTATED | 3 | 27 | 7 | 11 |
| 8P GAIN WILD-TYPE | 59 | 79 | 53 | 79 |
Figure S63. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00231 (Fisher's exact test), Q value = 0.0095
Table S64. Gene #15: '8p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 8P GAIN MUTATED | 4 | 6 | 6 | 24 | 2 | 6 |
| 8P GAIN WILD-TYPE | 66 | 35 | 34 | 58 | 23 | 54 |
Figure S64. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S65. Gene #16: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 8Q GAIN MUTATED | 36 | 77 | 11 |
| 8Q GAIN WILD-TYPE | 237 | 57 | 74 |
Figure S65. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S66. Gene #16: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 8Q GAIN MUTATED | 21 | 68 | 35 |
| 8Q GAIN WILD-TYPE | 139 | 97 | 132 |
Figure S66. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00027
Table S67. Gene #16: '8q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 8Q GAIN MUTATED | 21 | 63 | 40 |
| 8Q GAIN WILD-TYPE | 125 | 108 | 134 |
Figure S67. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00027
Table S68. Gene #16: '8q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 8Q GAIN MUTATED | 26 | 73 | 25 |
| 8Q GAIN WILD-TYPE | 145 | 132 | 90 |
Figure S68. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0027
Table S69. Gene #16: '8q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 8Q GAIN MUTATED | 29 | 29 | 64 |
| 8Q GAIN WILD-TYPE | 129 | 118 | 119 |
Figure S69. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S70. Gene #16: '8q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 8Q GAIN MUTATED | 17 | 24 | 18 | 54 | 9 |
| 8Q GAIN WILD-TYPE | 130 | 74 | 41 | 74 | 47 |
Figure S70. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S71. Gene #16: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 8Q GAIN MUTATED | 6 | 46 | 11 | 18 |
| 8Q GAIN WILD-TYPE | 56 | 60 | 49 | 72 |
Figure S71. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S72. Gene #16: '8q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 8Q GAIN MUTATED | 8 | 9 | 13 | 37 | 3 | 11 |
| 8Q GAIN WILD-TYPE | 62 | 32 | 27 | 45 | 22 | 49 |
Figure S72. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S73. Gene #17: '9p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 9P GAIN MUTATED | 4 | 30 | 0 |
| 9P GAIN WILD-TYPE | 269 | 104 | 85 |
Figure S73. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0166 (Fisher's exact test), Q value = 0.043
Table S74. Gene #17: '9p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 9P GAIN MUTATED | 2 | 13 | 1 | 3 |
| 9P GAIN WILD-TYPE | 60 | 93 | 59 | 87 |
Figure S74. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S75. Gene #18: '9q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 9Q GAIN MUTATED | 8 | 42 | 0 |
| 9Q GAIN WILD-TYPE | 265 | 92 | 85 |
Figure S75. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0148 (Fisher's exact test), Q value = 0.039
Table S76. Gene #18: '9q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 9Q GAIN MUTATED | 7 | 18 | 25 |
| 9Q GAIN WILD-TYPE | 139 | 153 | 149 |
Figure S76. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0106 (Fisher's exact test), Q value = 0.031
Table S77. Gene #18: '9q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 9Q GAIN MUTATED | 10 | 7 | 5 | 24 | 3 |
| 9Q GAIN WILD-TYPE | 137 | 91 | 54 | 104 | 53 |
Figure S77. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00707 (Fisher's exact test), Q value = 0.022
Table S78. Gene #18: '9q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 9Q GAIN MUTATED | 2 | 18 | 3 | 5 |
| 9Q GAIN WILD-TYPE | 60 | 88 | 57 | 85 |
Figure S78. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0136 (Fisher's exact test), Q value = 0.037
Table S79. Gene #18: '9q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 9Q GAIN MUTATED | 3 | 1 | 8 | 12 | 1 | 3 |
| 9Q GAIN WILD-TYPE | 67 | 40 | 32 | 70 | 24 | 57 |
Figure S79. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00062
Table S80. Gene #19: '10p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 10P GAIN MUTATED | 3 | 12 | 0 |
| 10P GAIN WILD-TYPE | 270 | 122 | 85 |
Figure S80. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0348 (Fisher's exact test), Q value = 0.075
Table S81. Gene #19: '10p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 10P GAIN MUTATED | 1 | 9 | 5 |
| 10P GAIN WILD-TYPE | 159 | 156 | 162 |
Figure S81. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0334 (Fisher's exact test), Q value = 0.073
Table S82. Gene #19: '10p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 10P GAIN MUTATED | 1 | 10 | 4 |
| 10P GAIN WILD-TYPE | 170 | 195 | 111 |
Figure S82. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0135 (Fisher's exact test), Q value = 0.037
Table S83. Gene #19: '10p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 10P GAIN MUTATED | 1 | 1 | 1 | 8 | 4 |
| 10P GAIN WILD-TYPE | 146 | 97 | 58 | 120 | 52 |
Figure S83. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00082 (Fisher's exact test), Q value = 0.0043
Table S84. Gene #19: '10p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 10P GAIN MUTATED | 1 | 0 | 8 | 3 | 0 | 2 |
| 10P GAIN WILD-TYPE | 69 | 41 | 32 | 79 | 25 | 58 |
Figure S84. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0014
Table S85. Gene #20: '10q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 10Q GAIN MUTATED | 3 | 11 | 0 |
| 10Q GAIN WILD-TYPE | 270 | 123 | 85 |
Figure S85. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0316 (Fisher's exact test), Q value = 0.07
Table S86. Gene #20: '10q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 10Q GAIN MUTATED | 1 | 10 | 3 |
| 10Q GAIN WILD-TYPE | 170 | 195 | 112 |
Figure S86. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00192 (Fisher's exact test), Q value = 0.0082
Table S87. Gene #20: '10q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 10Q GAIN MUTATED | 0 | 0 | 6 | 2 | 0 | 2 |
| 10Q GAIN WILD-TYPE | 70 | 41 | 34 | 80 | 25 | 58 |
Figure S87. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S88. Gene #21: '11p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 11P GAIN MUTATED | 3 | 21 | 2 |
| 11P GAIN WILD-TYPE | 270 | 113 | 83 |
Figure S88. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0142 (Fisher's exact test), Q value = 0.039
Table S89. Gene #21: '11p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 11P GAIN MUTATED | 4 | 18 | 4 |
| 11P GAIN WILD-TYPE | 167 | 187 | 111 |
Figure S89. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0356 (Fisher's exact test), Q value = 0.076
Table S90. Gene #21: '11p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 11P GAIN MUTATED | 1 | 11 | 2 | 2 |
| 11P GAIN WILD-TYPE | 61 | 95 | 58 | 88 |
Figure S90. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S91. Gene #22: '11q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 11Q GAIN MUTATED | 3 | 24 | 2 |
| 11Q GAIN WILD-TYPE | 270 | 110 | 83 |
Figure S91. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0309 (Fisher's exact test), Q value = 0.069
Table S92. Gene #22: '11q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 11Q GAIN MUTATED | 3 | 15 | 11 |
| 11Q GAIN WILD-TYPE | 143 | 156 | 163 |
Figure S92. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0381 (Fisher's exact test), Q value = 0.079
Table S93. Gene #22: '11q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 11Q GAIN MUTATED | 6 | 19 | 4 |
| 11Q GAIN WILD-TYPE | 165 | 186 | 111 |
Figure S93. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00027
Table S94. Gene #23: '12p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 12P GAIN MUTATED | 2 | 12 | 0 |
| 12P GAIN WILD-TYPE | 271 | 122 | 85 |
Figure S94. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00094 (Fisher's exact test), Q value = 0.0049
Table S95. Gene #23: '12p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 12P GAIN MUTATED | 1 | 1 | 1 | 11 | 0 |
| 12P GAIN WILD-TYPE | 146 | 97 | 58 | 117 | 56 |
Figure S95. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0233 (Fisher's exact test), Q value = 0.056
Table S96. Gene #23: '12p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 12P GAIN MUTATED | 0 | 8 | 1 | 1 |
| 12P GAIN WILD-TYPE | 62 | 98 | 59 | 89 |
Figure S96. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00039 (Fisher's exact test), Q value = 0.0024
Table S97. Gene #24: '12q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 12Q GAIN MUTATED | 5 | 12 | 0 |
| 12Q GAIN WILD-TYPE | 268 | 122 | 85 |
Figure S97. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0203 (Fisher's exact test), Q value = 0.051
Table S98. Gene #24: '12q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 12Q GAIN MUTATED | 3 | 1 | 3 | 10 | 0 |
| 12Q GAIN WILD-TYPE | 144 | 97 | 56 | 118 | 56 |
Figure S98. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0154 (Fisher's exact test), Q value = 0.04
Table S99. Gene #24: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 12Q GAIN MUTATED | 1 | 10 | 1 | 1 |
| 12Q GAIN WILD-TYPE | 61 | 96 | 59 | 89 |
Figure S99. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0144 (Fisher's exact test), Q value = 0.039
Table S100. Gene #25: '13q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 13Q GAIN MUTATED | 2 | 6 | 0 |
| 13Q GAIN WILD-TYPE | 271 | 128 | 85 |
Figure S100. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S101. Gene #26: '14q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 14Q GAIN MUTATED | 0 | 9 | 1 |
| 14Q GAIN WILD-TYPE | 273 | 125 | 84 |
Figure S101. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0201 (Fisher's exact test), Q value = 0.05
Table S102. Gene #27: '15q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 15Q GAIN MUTATED | 1 | 5 | 0 |
| 15Q GAIN WILD-TYPE | 272 | 129 | 85 |
Figure S102. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S103. Gene #28: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 16P GAIN MUTATED | 8 | 23 | 0 |
| 16P GAIN WILD-TYPE | 265 | 111 | 85 |
Figure S103. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00398 (Fisher's exact test), Q value = 0.014
Table S104. Gene #28: '16p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 16P GAIN MUTATED | 2 | 4 | 6 | 14 | 4 |
| 16P GAIN WILD-TYPE | 145 | 94 | 53 | 114 | 52 |
Figure S104. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0263 (Fisher's exact test), Q value = 0.062
Table S105. Gene #28: '16p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 16P GAIN MUTATED | 0 | 9 | 2 | 9 |
| 16P GAIN WILD-TYPE | 62 | 97 | 58 | 81 |
Figure S105. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0124 (Fisher's exact test), Q value = 0.035
Table S106. Gene #28: '16p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 16P GAIN MUTATED | 1 | 1 | 7 | 5 | 0 | 6 |
| 16P GAIN WILD-TYPE | 69 | 40 | 33 | 77 | 25 | 54 |
Figure S106. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0124 (Fisher's exact test), Q value = 0.035
Table S107. Gene #29: '16q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 16Q GAIN MUTATED | 0 | 0 | 1 | 6 | 1 |
| 16Q GAIN WILD-TYPE | 147 | 98 | 58 | 122 | 55 |
Figure S107. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0145 (Fisher's exact test), Q value = 0.039
Table S108. Gene #30: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 17P GAIN MUTATED | 2 | 6 | 0 |
| 17P GAIN WILD-TYPE | 271 | 128 | 85 |
Figure S108. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0491 (Fisher's exact test), Q value = 0.095
Table S109. Gene #30: '17p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 17P GAIN MUTATED | 0 | 2 | 6 |
| 17P GAIN WILD-TYPE | 146 | 169 | 168 |
Figure S109. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0212 (Fisher's exact test), Q value = 0.052
Table S110. Gene #30: '17p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 17P GAIN MUTATED | 6 | 0 | 2 |
| 17P GAIN WILD-TYPE | 152 | 147 | 181 |
Figure S110. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.042
Table S111. Gene #30: '17p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 17P GAIN MUTATED | 1 | 0 | 4 | 3 | 0 |
| 17P GAIN WILD-TYPE | 146 | 98 | 55 | 125 | 56 |
Figure S111. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00361 (Fisher's exact test), Q value = 0.013
Table S112. Gene #30: '17p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 17P GAIN MUTATED | 0 | 0 | 4 | 1 | 1 | 0 |
| 17P GAIN WILD-TYPE | 70 | 41 | 36 | 81 | 24 | 60 |
Figure S112. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00035 (Fisher's exact test), Q value = 0.0022
Table S113. Gene #31: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 17Q GAIN MUTATED | 2 | 9 | 0 |
| 17Q GAIN WILD-TYPE | 271 | 125 | 85 |
Figure S113. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0166 (Fisher's exact test), Q value = 0.043
Table S114. Gene #31: '17q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 17Q GAIN MUTATED | 0 | 3 | 8 |
| 17Q GAIN WILD-TYPE | 146 | 168 | 166 |
Figure S114. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0037
Table S115. Gene #31: '17q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 17Q GAIN MUTATED | 1 | 0 | 6 | 1 | 1 | 0 |
| 17Q GAIN WILD-TYPE | 69 | 41 | 34 | 81 | 24 | 60 |
Figure S115. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S116. Gene #32: '18p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 18P GAIN MUTATED | 3 | 15 | 0 |
| 18P GAIN WILD-TYPE | 270 | 119 | 85 |
Figure S116. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00473 (Fisher's exact test), Q value = 0.016
Table S117. Gene #33: '18q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 18Q GAIN MUTATED | 2 | 7 | 0 |
| 18Q GAIN WILD-TYPE | 271 | 127 | 85 |
Figure S117. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S118. Gene #34: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 19P GAIN MUTATED | 0 | 12 | 0 |
| 19P GAIN WILD-TYPE | 273 | 122 | 85 |
Figure S118. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0365 (Fisher's exact test), Q value = 0.076
Table S119. Gene #34: '19p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 19P GAIN MUTATED | 0 | 5 | 7 |
| 19P GAIN WILD-TYPE | 146 | 166 | 167 |
Figure S119. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S120. Gene #35: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 19Q GAIN MUTATED | 0 | 12 | 0 |
| 19Q GAIN WILD-TYPE | 273 | 122 | 85 |
Figure S120. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0391 (Fisher's exact test), Q value = 0.079
Table S121. Gene #35: '19q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 19Q GAIN MUTATED | 0 | 6 | 6 |
| 19Q GAIN WILD-TYPE | 146 | 165 | 168 |
Figure S121. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S122. Gene #36: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 20P GAIN MUTATED | 3 | 22 | 1 |
| 20P GAIN WILD-TYPE | 270 | 112 | 84 |
Figure S122. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0208 (Fisher's exact test), Q value = 0.051
Table S123. Gene #36: '20p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 20P GAIN MUTATED | 3 | 14 | 9 |
| 20P GAIN WILD-TYPE | 157 | 151 | 158 |
Figure S123. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.054
Table S124. Gene #36: '20p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 20P GAIN MUTATED | 2 | 11 | 13 |
| 20P GAIN WILD-TYPE | 144 | 160 | 161 |
Figure S124. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0364 (Fisher's exact test), Q value = 0.076
Table S125. Gene #36: '20p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 20P GAIN MUTATED | 4 | 17 | 5 |
| 20P GAIN WILD-TYPE | 167 | 188 | 110 |
Figure S125. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00213 (Fisher's exact test), Q value = 0.0089
Table S126. Gene #36: '20p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 20P GAIN MUTATED | 4 | 3 | 18 |
| 20P GAIN WILD-TYPE | 154 | 144 | 165 |
Figure S126. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00394 (Fisher's exact test), Q value = 0.014
Table S127. Gene #36: '20p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 20P GAIN MUTATED | 3 | 5 | 1 | 15 | 1 |
| 20P GAIN WILD-TYPE | 144 | 93 | 58 | 113 | 55 |
Figure S127. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0296 (Fisher's exact test), Q value = 0.067
Table S128. Gene #36: '20p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 20P GAIN MUTATED | 0 | 10 | 2 | 3 |
| 20P GAIN WILD-TYPE | 62 | 96 | 58 | 87 |
Figure S128. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00454 (Fisher's exact test), Q value = 0.016
Table S129. Gene #36: '20p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 20P GAIN MUTATED | 1 | 0 | 7 | 5 | 0 | 2 |
| 20P GAIN WILD-TYPE | 69 | 41 | 33 | 77 | 25 | 58 |
Figure S129. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S130. Gene #37: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 20Q GAIN MUTATED | 3 | 24 | 1 |
| 20Q GAIN WILD-TYPE | 270 | 110 | 84 |
Figure S130. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0199 (Fisher's exact test), Q value = 0.05
Table S131. Gene #37: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 20Q GAIN MUTATED | 4 | 16 | 8 |
| 20Q GAIN WILD-TYPE | 156 | 149 | 159 |
Figure S131. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0112 (Fisher's exact test), Q value = 0.032
Table S132. Gene #37: '20q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 20Q GAIN MUTATED | 4 | 6 | 18 |
| 20Q GAIN WILD-TYPE | 154 | 141 | 165 |
Figure S132. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00787 (Fisher's exact test), Q value = 0.024
Table S133. Gene #37: '20q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 20Q GAIN MUTATED | 4 | 7 | 1 | 15 | 1 |
| 20Q GAIN WILD-TYPE | 143 | 91 | 58 | 113 | 55 |
Figure S133. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00896 (Fisher's exact test), Q value = 0.027
Table S134. Gene #37: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 20Q GAIN MUTATED | 1 | 1 | 8 | 4 | 1 | 3 |
| 20Q GAIN WILD-TYPE | 69 | 40 | 32 | 78 | 24 | 57 |
Figure S134. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S135. Gene #38: '21q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 21Q GAIN MUTATED | 0 | 21 | 0 |
| 21Q GAIN WILD-TYPE | 273 | 113 | 85 |
Figure S135. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0386 (Fisher's exact test), Q value = 0.079
Table S136. Gene #38: '21q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 21Q GAIN MUTATED | 2 | 11 | 8 |
| 21Q GAIN WILD-TYPE | 158 | 154 | 159 |
Figure S136. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00156 (Fisher's exact test), Q value = 0.0072
Table S137. Gene #38: '21q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 21Q GAIN MUTATED | 0 | 11 | 10 |
| 21Q GAIN WILD-TYPE | 146 | 160 | 164 |
Figure S137. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0264 (Fisher's exact test), Q value = 0.062
Table S138. Gene #38: '21q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 21Q GAIN MUTATED | 2 | 13 | 6 |
| 21Q GAIN WILD-TYPE | 169 | 192 | 109 |
Figure S138. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0137 (Fisher's exact test), Q value = 0.038
Table S139. Gene #38: '21q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 21Q GAIN MUTATED | 2 | 5 | 14 |
| 21Q GAIN WILD-TYPE | 156 | 142 | 169 |
Figure S139. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00347 (Fisher's exact test), Q value = 0.013
Table S140. Gene #38: '21q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 21Q GAIN MUTATED | 1 | 3 | 2 | 13 | 2 |
| 21Q GAIN WILD-TYPE | 146 | 95 | 57 | 115 | 54 |
Figure S140. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0124 (Fisher's exact test), Q value = 0.035
Table S141. Gene #38: '21q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 21Q GAIN MUTATED | 0 | 11 | 1 | 5 |
| 21Q GAIN WILD-TYPE | 62 | 95 | 59 | 85 |
Figure S141. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0292 (Fisher's exact test), Q value = 0.067
Table S142. Gene #38: '21q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 21Q GAIN MUTATED | 1 | 1 | 6 | 7 | 0 | 2 |
| 21Q GAIN WILD-TYPE | 69 | 40 | 34 | 75 | 25 | 58 |
Figure S142. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00082 (Fisher's exact test), Q value = 0.0043
Table S143. Gene #40: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| XP GAIN MUTATED | 0 | 6 | 1 |
| XP GAIN WILD-TYPE | 273 | 128 | 84 |
Figure S143. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.045 (Fisher's exact test), Q value = 0.089
Table S144. Gene #40: 'xp gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| XP GAIN MUTATED | 0 | 2 | 0 | 5 | 0 |
| XP GAIN WILD-TYPE | 147 | 96 | 59 | 123 | 56 |
Figure S144. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00615 (Fisher's exact test), Q value = 0.02
Table S145. Gene #40: 'xp gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| XP GAIN MUTATED | 0 | 6 | 0 | 0 |
| XP GAIN WILD-TYPE | 62 | 100 | 60 | 90 |
Figure S145. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00106 (Fisher's exact test), Q value = 0.0053
Table S146. Gene #41: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| XQ GAIN MUTATED | 0 | 6 | 1 |
| XQ GAIN WILD-TYPE | 273 | 128 | 84 |
Figure S146. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0456 (Fisher's exact test), Q value = 0.09
Table S147. Gene #41: 'xq gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| XQ GAIN MUTATED | 0 | 2 | 0 | 5 | 0 |
| XQ GAIN WILD-TYPE | 147 | 96 | 59 | 123 | 56 |
Figure S147. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0064 (Fisher's exact test), Q value = 0.02
Table S148. Gene #41: 'xq gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| XQ GAIN MUTATED | 0 | 6 | 0 | 0 |
| XQ GAIN WILD-TYPE | 62 | 100 | 60 | 90 |
Figure S148. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S149. Gene #42: '1p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 1P LOSS MUTATED | 1 | 20 | 1 |
| 1P LOSS WILD-TYPE | 272 | 114 | 84 |
Figure S149. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00057 (Fisher's exact test), Q value = 0.0032
Table S150. Gene #42: '1p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 1P LOSS MUTATED | 0 | 11 | 11 |
| 1P LOSS WILD-TYPE | 160 | 154 | 156 |
Figure S150. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00122 (Fisher's exact test), Q value = 0.0059
Table S151. Gene #42: '1p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 1P LOSS MUTATED | 0 | 11 | 11 |
| 1P LOSS WILD-TYPE | 146 | 160 | 163 |
Figure S151. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.0013
Table S152. Gene #42: '1p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 1P LOSS MUTATED | 0 | 13 | 9 |
| 1P LOSS WILD-TYPE | 171 | 192 | 106 |
Figure S152. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0251 (Fisher's exact test), Q value = 0.059
Table S153. Gene #42: '1p loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 1P LOSS MUTATED | 2 | 6 | 13 |
| 1P LOSS WILD-TYPE | 156 | 141 | 170 |
Figure S153. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00364 (Fisher's exact test), Q value = 0.013
Table S154. Gene #42: '1p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 1P LOSS MUTATED | 1 | 3 | 4 | 12 | 1 |
| 1P LOSS WILD-TYPE | 146 | 95 | 55 | 116 | 55 |
Figure S154. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0196 (Fisher's exact test), Q value = 0.05
Table S155. Gene #42: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 1P LOSS MUTATED | 0 | 11 | 4 | 3 |
| 1P LOSS WILD-TYPE | 62 | 95 | 56 | 87 |
Figure S155. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0132 (Fisher's exact test), Q value = 0.037
Table S156. Gene #42: '1p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 1P LOSS MUTATED | 0 | 1 | 5 | 8 | 0 | 4 |
| 1P LOSS WILD-TYPE | 70 | 40 | 35 | 74 | 25 | 56 |
Figure S156. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0206 (Fisher's exact test), Q value = 0.051
Table S157. Gene #43: '1q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 1Q LOSS MUTATED | 1 | 5 | 0 |
| 1Q LOSS WILD-TYPE | 272 | 129 | 85 |
Figure S157. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0425 (Fisher's exact test), Q value = 0.085
Table S158. Gene #43: '1q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 1Q LOSS MUTATED | 0 | 5 | 1 |
| 1Q LOSS WILD-TYPE | 146 | 166 | 173 |
Figure S158. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00069
Table S159. Gene #44: '2p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 2P LOSS MUTATED | 2 | 12 | 2 |
| 2P LOSS WILD-TYPE | 271 | 122 | 83 |
Figure S159. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00486 (Fisher's exact test), Q value = 0.017
Table S160. Gene #44: '2p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 2P LOSS MUTATED | 0 | 9 | 7 |
| 2P LOSS WILD-TYPE | 160 | 156 | 160 |
Figure S160. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00389 (Fisher's exact test), Q value = 0.014
Table S161. Gene #44: '2p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 2P LOSS MUTATED | 0 | 11 | 1 | 2 |
| 2P LOSS WILD-TYPE | 62 | 95 | 59 | 88 |
Figure S161. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00345 (Fisher's exact test), Q value = 0.013
Table S162. Gene #44: '2p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 2P LOSS MUTATED | 0 | 0 | 2 | 10 | 0 | 2 |
| 2P LOSS WILD-TYPE | 70 | 41 | 38 | 72 | 25 | 58 |
Figure S162. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00014 (Fisher's exact test), Q value = 0.00098
Table S163. Gene #45: '2q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 2Q LOSS MUTATED | 3 | 13 | 2 |
| 2Q LOSS WILD-TYPE | 270 | 121 | 83 |
Figure S163. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0205 (Fisher's exact test), Q value = 0.051
Table S164. Gene #45: '2q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 2Q LOSS MUTATED | 1 | 10 | 7 |
| 2Q LOSS WILD-TYPE | 159 | 155 | 160 |
Figure S164. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0349 (Fisher's exact test), Q value = 0.075
Table S165. Gene #45: '2q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 2Q LOSS MUTATED | 3 | 2 | 0 | 10 | 3 |
| 2Q LOSS WILD-TYPE | 144 | 96 | 59 | 118 | 53 |
Figure S165. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00882 (Fisher's exact test), Q value = 0.027
Table S166. Gene #45: '2q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 2Q LOSS MUTATED | 0 | 11 | 1 | 3 |
| 2Q LOSS WILD-TYPE | 62 | 95 | 59 | 87 |
Figure S166. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.001 (Fisher's exact test), Q value = 0.005
Table S167. Gene #45: '2q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 2Q LOSS MUTATED | 0 | 0 | 1 | 11 | 0 | 3 |
| 2Q LOSS WILD-TYPE | 70 | 41 | 39 | 71 | 25 | 57 |
Figure S167. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0336 (Fisher's exact test), Q value = 0.073
Table S168. Gene #46: '3p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 3P LOSS MUTATED | 3 | 6 | 0 |
| 3P LOSS WILD-TYPE | 270 | 128 | 85 |
Figure S168. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0385 (Fisher's exact test), Q value = 0.079
Table S169. Gene #46: '3p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 3P LOSS MUTATED | 0 | 5 | 4 |
| 3P LOSS WILD-TYPE | 171 | 200 | 111 |
Figure S169. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0317 (Fisher's exact test), Q value = 0.07
Table S170. Gene #47: '3q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 3Q LOSS MUTATED | 0 | 3 | 1 | 0 | 0 |
| 3Q LOSS WILD-TYPE | 147 | 95 | 58 | 128 | 56 |
Figure S170. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S171. Gene #48: '4p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 4P LOSS MUTATED | 2 | 21 | 1 |
| 4P LOSS WILD-TYPE | 271 | 113 | 84 |
Figure S171. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0189 (Fisher's exact test), Q value = 0.048
Table S172. Gene #48: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 4P LOSS MUTATED | 2 | 12 | 10 |
| 4P LOSS WILD-TYPE | 158 | 153 | 157 |
Figure S172. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00375 (Fisher's exact test), Q value = 0.014
Table S173. Gene #48: '4p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 4P LOSS MUTATED | 1 | 9 | 14 |
| 4P LOSS WILD-TYPE | 145 | 162 | 160 |
Figure S173. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0295 (Fisher's exact test), Q value = 0.067
Table S174. Gene #48: '4p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 4P LOSS MUTATED | 3 | 12 | 9 |
| 4P LOSS WILD-TYPE | 168 | 193 | 106 |
Figure S174. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00152 (Fisher's exact test), Q value = 0.007
Table S175. Gene #48: '4p loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 4P LOSS MUTATED | 6 | 1 | 16 |
| 4P LOSS WILD-TYPE | 152 | 146 | 167 |
Figure S175. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00258 (Fisher's exact test), Q value = 0.01
Table S176. Gene #48: '4p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 4P LOSS MUTATED | 6 | 1 | 2 | 14 | 0 |
| 4P LOSS WILD-TYPE | 141 | 97 | 57 | 114 | 56 |
Figure S176. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00035
Table S177. Gene #48: '4p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 4P LOSS MUTATED | 0 | 14 | 3 | 0 |
| 4P LOSS WILD-TYPE | 62 | 92 | 57 | 90 |
Figure S177. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00056
Table S178. Gene #48: '4p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 4P LOSS MUTATED | 1 | 0 | 7 | 9 | 0 | 0 |
| 4P LOSS WILD-TYPE | 69 | 41 | 33 | 73 | 25 | 60 |
Figure S178. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S179. Gene #49: '4q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 4Q LOSS MUTATED | 2 | 15 | 0 |
| 4Q LOSS WILD-TYPE | 271 | 119 | 85 |
Figure S179. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00638 (Fisher's exact test), Q value = 0.02
Table S180. Gene #49: '4q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 4Q LOSS MUTATED | 0 | 8 | 9 |
| 4Q LOSS WILD-TYPE | 146 | 163 | 165 |
Figure S180. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0466 (Fisher's exact test), Q value = 0.092
Table S181. Gene #49: '4q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 4Q LOSS MUTATED | 3 | 1 | 1 | 10 | 1 |
| 4Q LOSS WILD-TYPE | 144 | 97 | 58 | 118 | 55 |
Figure S181. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0144 (Fisher's exact test), Q value = 0.039
Table S182. Gene #49: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 4Q LOSS MUTATED | 0 | 9 | 2 | 1 |
| 4Q LOSS WILD-TYPE | 62 | 97 | 58 | 89 |
Figure S182. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00521 (Fisher's exact test), Q value = 0.017
Table S183. Gene #49: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 4Q LOSS MUTATED | 2 | 0 | 6 | 4 | 0 | 0 |
| 4Q LOSS WILD-TYPE | 68 | 41 | 34 | 78 | 25 | 60 |
Figure S183. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S184. Gene #50: '5p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 5P LOSS MUTATED | 1 | 11 | 0 |
| 5P LOSS WILD-TYPE | 272 | 123 | 85 |
Figure S184. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0376 (Fisher's exact test), Q value = 0.078
Table S185. Gene #50: '5p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 5P LOSS MUTATED | 0 | 6 | 6 |
| 5P LOSS WILD-TYPE | 146 | 165 | 168 |
Figure S185. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00562 (Fisher's exact test), Q value = 0.018
Table S186. Gene #50: '5p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 5P LOSS MUTATED | 0 | 6 | 6 |
| 5P LOSS WILD-TYPE | 171 | 199 | 109 |
Figure S186. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00319 (Fisher's exact test), Q value = 0.012
Table S187. Gene #50: '5p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 5P LOSS MUTATED | 0 | 1 | 4 | 6 | 0 |
| 5P LOSS WILD-TYPE | 147 | 97 | 55 | 122 | 56 |
Figure S187. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S188. Gene #51: '5q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 5Q LOSS MUTATED | 0 | 22 | 0 |
| 5Q LOSS WILD-TYPE | 273 | 112 | 85 |
Figure S188. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00293 (Fisher's exact test), Q value = 0.012
Table S189. Gene #51: '5q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 5Q LOSS MUTATED | 1 | 13 | 8 |
| 5Q LOSS WILD-TYPE | 159 | 152 | 159 |
Figure S189. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0124 (Fisher's exact test), Q value = 0.035
Table S190. Gene #51: '5q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 5Q LOSS MUTATED | 1 | 11 | 10 |
| 5Q LOSS WILD-TYPE | 145 | 160 | 164 |
Figure S190. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00216 (Fisher's exact test), Q value = 0.0089
Table S191. Gene #51: '5q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 5Q LOSS MUTATED | 1 | 15 | 6 |
| 5Q LOSS WILD-TYPE | 170 | 190 | 109 |
Figure S191. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00111 (Fisher's exact test), Q value = 0.0055
Table S192. Gene #51: '5q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 5Q LOSS MUTATED | 1 | 2 | 5 | 12 | 1 |
| 5Q LOSS WILD-TYPE | 146 | 96 | 54 | 116 | 55 |
Figure S192. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.027 (Fisher's exact test), Q value = 0.063
Table S193. Gene #51: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 5Q LOSS MUTATED | 0 | 0 | 3 | 7 | 0 | 2 |
| 5Q LOSS WILD-TYPE | 70 | 41 | 37 | 75 | 25 | 58 |
Figure S193. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S194. Gene #52: '6p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 6P LOSS MUTATED | 4 | 21 | 0 |
| 6P LOSS WILD-TYPE | 269 | 113 | 85 |
Figure S194. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0147 (Fisher's exact test), Q value = 0.039
Table S195. Gene #52: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 6P LOSS MUTATED | 2 | 11 | 12 |
| 6P LOSS WILD-TYPE | 158 | 154 | 155 |
Figure S195. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.002
Table S196. Gene #52: '6p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 6P LOSS MUTATED | 0 | 10 | 15 |
| 6P LOSS WILD-TYPE | 146 | 161 | 159 |
Figure S196. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00298 (Fisher's exact test), Q value = 0.012
Table S197. Gene #52: '6p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 6P LOSS MUTATED | 2 | 12 | 11 |
| 6P LOSS WILD-TYPE | 169 | 193 | 104 |
Figure S197. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0316 (Fisher's exact test), Q value = 0.07
Table S198. Gene #52: '6p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 6P LOSS MUTATED | 2 | 5 | 4 | 12 | 2 |
| 6P LOSS WILD-TYPE | 145 | 93 | 55 | 116 | 54 |
Figure S198. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0141 (Fisher's exact test), Q value = 0.038
Table S199. Gene #52: '6p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 6P LOSS MUTATED | 0 | 11 | 2 | 3 |
| 6P LOSS WILD-TYPE | 62 | 95 | 58 | 87 |
Figure S199. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00402 (Fisher's exact test), Q value = 0.014
Table S200. Gene #52: '6p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 6P LOSS MUTATED | 0 | 0 | 5 | 8 | 0 | 3 |
| 6P LOSS WILD-TYPE | 70 | 41 | 35 | 74 | 25 | 57 |
Figure S200. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S201. Gene #53: '6q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 6Q LOSS MUTATED | 5 | 32 | 3 |
| 6Q LOSS WILD-TYPE | 268 | 102 | 82 |
Figure S201. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0358 (Fisher's exact test), Q value = 0.076
Table S202. Gene #53: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 6Q LOSS MUTATED | 6 | 17 | 17 |
| 6Q LOSS WILD-TYPE | 154 | 148 | 150 |
Figure S202. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0022
Table S203. Gene #53: '6q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 6Q LOSS MUTATED | 2 | 19 | 19 |
| 6Q LOSS WILD-TYPE | 144 | 152 | 155 |
Figure S203. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00124 (Fisher's exact test), Q value = 0.0059
Table S204. Gene #53: '6q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 6Q LOSS MUTATED | 4 | 24 | 12 |
| 6Q LOSS WILD-TYPE | 167 | 181 | 103 |
Figure S204. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.013 (Fisher's exact test), Q value = 0.036
Table S205. Gene #53: '6q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 6Q LOSS MUTATED | 8 | 8 | 24 |
| 6Q LOSS WILD-TYPE | 150 | 139 | 159 |
Figure S205. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.0477 (Fisher's exact test), Q value = 0.093
Table S206. Gene #53: '6q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 6Q LOSS MUTATED | 5 | 8 | 7 | 16 | 4 |
| 6Q LOSS WILD-TYPE | 142 | 90 | 52 | 112 | 52 |
Figure S206. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00407 (Fisher's exact test), Q value = 0.014
Table S207. Gene #53: '6q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 6Q LOSS MUTATED | 1 | 17 | 2 | 8 |
| 6Q LOSS WILD-TYPE | 61 | 89 | 58 | 82 |
Figure S207. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00207 (Fisher's exact test), Q value = 0.0087
Table S208. Gene #53: '6q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 6Q LOSS MUTATED | 2 | 1 | 8 | 13 | 0 | 4 |
| 6Q LOSS WILD-TYPE | 68 | 40 | 32 | 69 | 25 | 56 |
Figure S208. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S209. Gene #54: '8p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 8P LOSS MUTATED | 104 | 55 | 9 |
| 8P LOSS WILD-TYPE | 169 | 79 | 76 |
Figure S209. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S210. Gene #54: '8p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 8P LOSS MUTATED | 27 | 56 | 85 |
| 8P LOSS WILD-TYPE | 133 | 109 | 82 |
Figure S210. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S211. Gene #54: '8p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 8P LOSS MUTATED | 33 | 46 | 89 |
| 8P LOSS WILD-TYPE | 113 | 125 | 85 |
Figure S211. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S212. Gene #54: '8p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 8P LOSS MUTATED | 39 | 68 | 61 |
| 8P LOSS WILD-TYPE | 132 | 137 | 54 |
Figure S212. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00044 (Fisher's exact test), Q value = 0.0026
Table S213. Gene #54: '8p loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 8P LOSS MUTATED | 43 | 41 | 83 |
| 8P LOSS WILD-TYPE | 115 | 106 | 100 |
Figure S213. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.0309 (Fisher's exact test), Q value = 0.069
Table S214. Gene #54: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 8P LOSS MUTATED | 16 | 7 | 18 | 24 | 5 | 23 |
| 8P LOSS WILD-TYPE | 54 | 34 | 22 | 58 | 20 | 37 |
Figure S214. Get High-res Image Gene #54: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0289 (Fisher's exact test), Q value = 0.067
Table S215. Gene #55: '8q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 8Q LOSS MUTATED | 11 | 12 | 1 |
| 8Q LOSS WILD-TYPE | 262 | 122 | 84 |
Figure S215. Get High-res Image Gene #55: '8q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.001 (Fisher's exact test), Q value = 0.005
Table S216. Gene #55: '8q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 8Q LOSS MUTATED | 1 | 8 | 15 |
| 8Q LOSS WILD-TYPE | 159 | 157 | 152 |
Figure S216. Get High-res Image Gene #55: '8q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0105 (Fisher's exact test), Q value = 0.031
Table S217. Gene #55: '8q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 8Q LOSS MUTATED | 2 | 7 | 15 |
| 8Q LOSS WILD-TYPE | 144 | 164 | 159 |
Figure S217. Get High-res Image Gene #55: '8q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0249 (Fisher's exact test), Q value = 0.059
Table S218. Gene #55: '8q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 8Q LOSS MUTATED | 4 | 9 | 11 |
| 8Q LOSS WILD-TYPE | 167 | 196 | 104 |
Figure S218. Get High-res Image Gene #55: '8q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S219. Gene #56: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 9P LOSS MUTATED | 5 | 16 | 0 |
| 9P LOSS WILD-TYPE | 268 | 118 | 85 |
Figure S219. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00415 (Fisher's exact test), Q value = 0.015
Table S220. Gene #56: '9p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 9P LOSS MUTATED | 1 | 6 | 14 |
| 9P LOSS WILD-TYPE | 145 | 165 | 160 |
Figure S220. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0211 (Fisher's exact test), Q value = 0.051
Table S221. Gene #56: '9p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 9P LOSS MUTATED | 3 | 8 | 10 |
| 9P LOSS WILD-TYPE | 168 | 197 | 105 |
Figure S221. Get High-res Image Gene #56: '9p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00163 (Fisher's exact test), Q value = 0.0073
Table S222. Gene #57: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 9Q LOSS MUTATED | 2 | 8 | 0 |
| 9Q LOSS WILD-TYPE | 271 | 126 | 85 |
Figure S222. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0364 (Fisher's exact test), Q value = 0.076
Table S223. Gene #57: '9q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 9Q LOSS MUTATED | 0 | 0 | 4 | 3 | 0 | 1 |
| 9Q LOSS WILD-TYPE | 70 | 41 | 36 | 79 | 25 | 59 |
Figure S223. Get High-res Image Gene #57: '9q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S224. Gene #58: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 10P LOSS MUTATED | 9 | 30 | 2 |
| 10P LOSS WILD-TYPE | 264 | 104 | 83 |
Figure S224. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00081
Table S225. Gene #58: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 10P LOSS MUTATED | 2 | 17 | 22 |
| 10P LOSS WILD-TYPE | 158 | 148 | 145 |
Figure S225. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0017
Table S226. Gene #58: '10p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 10P LOSS MUTATED | 2 | 18 | 21 |
| 10P LOSS WILD-TYPE | 144 | 153 | 153 |
Figure S226. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00074
Table S227. Gene #58: '10p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 10P LOSS MUTATED | 3 | 22 | 16 |
| 10P LOSS WILD-TYPE | 168 | 183 | 99 |
Figure S227. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00043
Table S228. Gene #58: '10p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 10P LOSS MUTATED | 3 | 5 | 7 | 22 | 2 |
| 10P LOSS WILD-TYPE | 144 | 93 | 52 | 106 | 54 |
Figure S228. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0113 (Fisher's exact test), Q value = 0.032
Table S229. Gene #58: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 10P LOSS MUTATED | 0 | 12 | 3 | 10 |
| 10P LOSS WILD-TYPE | 62 | 94 | 57 | 80 |
Figure S229. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00043
Table S230. Gene #58: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 10P LOSS MUTATED | 0 | 0 | 6 | 13 | 0 | 6 |
| 10P LOSS WILD-TYPE | 70 | 41 | 34 | 69 | 25 | 54 |
Figure S230. Get High-res Image Gene #58: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S231. Gene #59: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 10Q LOSS MUTATED | 9 | 31 | 3 |
| 10Q LOSS WILD-TYPE | 264 | 103 | 82 |
Figure S231. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00086 (Fisher's exact test), Q value = 0.0045
Table S232. Gene #59: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 10Q LOSS MUTATED | 4 | 17 | 22 |
| 10Q LOSS WILD-TYPE | 156 | 148 | 145 |
Figure S232. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00201 (Fisher's exact test), Q value = 0.0085
Table S233. Gene #59: '10q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 10Q LOSS MUTATED | 4 | 16 | 23 |
| 10Q LOSS WILD-TYPE | 142 | 155 | 151 |
Figure S233. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.0029
Table S234. Gene #59: '10q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 10Q LOSS MUTATED | 5 | 20 | 18 |
| 10Q LOSS WILD-TYPE | 166 | 185 | 97 |
Figure S234. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0391 (Fisher's exact test), Q value = 0.079
Table S235. Gene #59: '10q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 10Q LOSS MUTATED | 8 | 10 | 23 |
| 10Q LOSS WILD-TYPE | 150 | 137 | 160 |
Figure S235. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00125 (Fisher's exact test), Q value = 0.0059
Table S236. Gene #59: '10q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 10Q LOSS MUTATED | 5 | 4 | 6 | 21 | 5 |
| 10Q LOSS WILD-TYPE | 142 | 94 | 53 | 107 | 51 |
Figure S236. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00174 (Fisher's exact test), Q value = 0.0076
Table S237. Gene #59: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 10Q LOSS MUTATED | 0 | 14 | 3 | 13 |
| 10Q LOSS WILD-TYPE | 62 | 92 | 57 | 77 |
Figure S237. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00056
Table S238. Gene #59: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 10Q LOSS MUTATED | 1 | 0 | 9 | 12 | 0 | 8 |
| 10Q LOSS WILD-TYPE | 69 | 41 | 31 | 70 | 25 | 52 |
Figure S238. Get High-res Image Gene #59: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0024 (Fisher's exact test), Q value = 0.0098
Table S239. Gene #60: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 11P LOSS MUTATED | 1 | 7 | 0 |
| 11P LOSS WILD-TYPE | 272 | 127 | 85 |
Figure S239. Get High-res Image Gene #60: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.038
Table S240. Gene #61: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 11Q LOSS MUTATED | 0 | 4 | 1 |
| 11Q LOSS WILD-TYPE | 273 | 130 | 84 |
Figure S240. Get High-res Image Gene #61: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0218 (Fisher's exact test), Q value = 0.053
Table S241. Gene #61: '11q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 11Q LOSS MUTATED | 0 | 5 | 0 | 0 |
| 11Q LOSS WILD-TYPE | 62 | 101 | 60 | 90 |
Figure S241. Get High-res Image Gene #61: '11q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S242. Gene #62: '12p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 12P LOSS MUTATED | 22 | 26 | 0 |
| 12P LOSS WILD-TYPE | 251 | 108 | 85 |
Figure S242. Get High-res Image Gene #62: '12p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0485 (Fisher's exact test), Q value = 0.095
Table S243. Gene #62: '12p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 12P LOSS MUTATED | 11 | 12 | 25 |
| 12P LOSS WILD-TYPE | 135 | 159 | 149 |
Figure S243. Get High-res Image Gene #62: '12p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0164 (Fisher's exact test), Q value = 0.043
Table S244. Gene #62: '12p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 12P LOSS MUTATED | 13 | 4 | 11 | 15 | 2 |
| 12P LOSS WILD-TYPE | 134 | 94 | 48 | 113 | 54 |
Figure S244. Get High-res Image Gene #62: '12p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00684 (Fisher's exact test), Q value = 0.021
Table S245. Gene #62: '12p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 12P LOSS MUTATED | 4 | 20 | 3 | 5 |
| 12P LOSS WILD-TYPE | 58 | 86 | 57 | 85 |
Figure S245. Get High-res Image Gene #62: '12p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00272 (Fisher's exact test), Q value = 0.011
Table S246. Gene #62: '12p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 12P LOSS MUTATED | 3 | 0 | 7 | 15 | 3 | 4 |
| 12P LOSS WILD-TYPE | 67 | 41 | 33 | 67 | 22 | 56 |
Figure S246. Get High-res Image Gene #62: '12p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00027
Table S247. Gene #63: '12q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 12Q LOSS MUTATED | 5 | 15 | 0 |
| 12Q LOSS WILD-TYPE | 268 | 119 | 85 |
Figure S247. Get High-res Image Gene #63: '12q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0493 (Fisher's exact test), Q value = 0.095
Table S248. Gene #63: '12q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 12Q LOSS MUTATED | 3 | 4 | 6 | 5 | 0 |
| 12Q LOSS WILD-TYPE | 144 | 94 | 53 | 123 | 56 |
Figure S248. Get High-res Image Gene #63: '12q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00892 (Fisher's exact test), Q value = 0.027
Table S249. Gene #63: '12q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 12Q LOSS MUTATED | 0 | 0 | 5 | 7 | 1 | 2 |
| 12Q LOSS WILD-TYPE | 70 | 41 | 35 | 75 | 24 | 58 |
Figure S249. Get High-res Image Gene #63: '12q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S250. Gene #64: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 13Q LOSS MUTATED | 19 | 49 | 9 |
| 13Q LOSS WILD-TYPE | 254 | 85 | 76 |
Figure S250. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0419 (Fisher's exact test), Q value = 0.084
Table S251. Gene #64: '13q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 13Q LOSS MUTATED | 14 | 30 | 33 |
| 13Q LOSS WILD-TYPE | 132 | 141 | 141 |
Figure S251. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0408 (Fisher's exact test), Q value = 0.082
Table S252. Gene #64: '13q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 13Q LOSS MUTATED | 16 | 15 | 9 | 30 | 5 |
| 13Q LOSS WILD-TYPE | 131 | 83 | 50 | 98 | 51 |
Figure S252. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.0011
Table S253. Gene #64: '13q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 13Q LOSS MUTATED | 4 | 5 | 14 | 21 | 2 | 6 |
| 13Q LOSS WILD-TYPE | 66 | 36 | 26 | 61 | 23 | 54 |
Figure S253. Get High-res Image Gene #64: '13q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S254. Gene #65: '14q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 14Q LOSS MUTATED | 6 | 18 | 1 |
| 14Q LOSS WILD-TYPE | 267 | 116 | 84 |
Figure S254. Get High-res Image Gene #65: '14q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S255. Gene #66: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 15Q LOSS MUTATED | 4 | 30 | 2 |
| 15Q LOSS WILD-TYPE | 269 | 104 | 83 |
Figure S255. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00166 (Fisher's exact test), Q value = 0.0074
Table S256. Gene #66: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 15Q LOSS MUTATED | 3 | 18 | 15 |
| 15Q LOSS WILD-TYPE | 157 | 147 | 152 |
Figure S256. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00068 (Fisher's exact test), Q value = 0.0037
Table S257. Gene #66: '15q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 15Q LOSS MUTATED | 2 | 20 | 14 |
| 15Q LOSS WILD-TYPE | 144 | 151 | 160 |
Figure S257. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00648 (Fisher's exact test), Q value = 0.021
Table S258. Gene #66: '15q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 15Q LOSS MUTATED | 5 | 23 | 8 |
| 15Q LOSS WILD-TYPE | 166 | 182 | 107 |
Figure S258. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00074
Table S259. Gene #66: '15q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 15Q LOSS MUTATED | 2 | 10 | 23 |
| 15Q LOSS WILD-TYPE | 156 | 137 | 160 |
Figure S259. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.00751 (Fisher's exact test), Q value = 0.023
Table S260. Gene #66: '15q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 15Q LOSS MUTATED | 3 | 7 | 3 | 15 | 7 |
| 15Q LOSS WILD-TYPE | 144 | 91 | 56 | 113 | 49 |
Figure S260. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00116 (Fisher's exact test), Q value = 0.0057
Table S261. Gene #66: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 15Q LOSS MUTATED | 0 | 17 | 3 | 7 |
| 15Q LOSS WILD-TYPE | 62 | 89 | 57 | 83 |
Figure S261. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.00095
Table S262. Gene #66: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 15Q LOSS MUTATED | 0 | 1 | 8 | 12 | 0 | 6 |
| 15Q LOSS WILD-TYPE | 70 | 40 | 32 | 70 | 25 | 54 |
Figure S262. Get High-res Image Gene #66: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00175 (Fisher's exact test), Q value = 0.0076
Table S263. Gene #67: '16p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 16P LOSS MUTATED | 11 | 18 | 3 |
| 16P LOSS WILD-TYPE | 262 | 116 | 82 |
Figure S263. Get High-res Image Gene #67: '16p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0316 (Fisher's exact test), Q value = 0.07
Table S264. Gene #67: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 16P LOSS MUTATED | 2 | 3 | 5 | 14 | 1 | 3 |
| 16P LOSS WILD-TYPE | 68 | 38 | 35 | 68 | 24 | 57 |
Figure S264. Get High-res Image Gene #67: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S265. Gene #68: '16q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 16Q LOSS MUTATED | 40 | 62 | 5 |
| 16Q LOSS WILD-TYPE | 233 | 72 | 80 |
Figure S265. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0037
Table S266. Gene #68: '16q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 16Q LOSS MUTATED | 19 | 44 | 44 |
| 16Q LOSS WILD-TYPE | 141 | 121 | 123 |
Figure S266. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0306 (Fisher's exact test), Q value = 0.069
Table S267. Gene #68: '16q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 16Q LOSS MUTATED | 21 | 42 | 44 |
| 16Q LOSS WILD-TYPE | 125 | 129 | 130 |
Figure S267. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0304 (Fisher's exact test), Q value = 0.069
Table S268. Gene #68: '16q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 16Q LOSS MUTATED | 26 | 51 | 30 |
| 16Q LOSS WILD-TYPE | 145 | 154 | 85 |
Figure S268. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00054 (Fisher's exact test), Q value = 0.0031
Table S269. Gene #68: '16q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 16Q LOSS MUTATED | 20 | 15 | 18 | 42 | 10 |
| 16Q LOSS WILD-TYPE | 127 | 83 | 41 | 86 | 46 |
Figure S269. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00422 (Fisher's exact test), Q value = 0.015
Table S270. Gene #68: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 16Q LOSS MUTATED | 6 | 35 | 12 | 18 |
| 16Q LOSS WILD-TYPE | 56 | 71 | 48 | 72 |
Figure S270. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00062
Table S271. Gene #68: '16q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 16Q LOSS MUTATED | 7 | 4 | 15 | 30 | 3 | 12 |
| 16Q LOSS WILD-TYPE | 63 | 37 | 25 | 52 | 22 | 48 |
Figure S271. Get High-res Image Gene #68: '16q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S272. Gene #69: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 17P LOSS MUTATED | 21 | 52 | 3 |
| 17P LOSS WILD-TYPE | 252 | 82 | 82 |
Figure S272. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00157 (Fisher's exact test), Q value = 0.0072
Table S273. Gene #69: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 17P LOSS MUTATED | 12 | 29 | 35 |
| 17P LOSS WILD-TYPE | 148 | 136 | 132 |
Figure S273. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00098
Table S274. Gene #69: '17p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 17P LOSS MUTATED | 10 | 25 | 41 |
| 17P LOSS WILD-TYPE | 136 | 146 | 133 |
Figure S274. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.00171 (Fisher's exact test), Q value = 0.0075
Table S275. Gene #69: '17p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 17P LOSS MUTATED | 16 | 31 | 29 |
| 17P LOSS WILD-TYPE | 155 | 174 | 86 |
Figure S275. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0318 (Fisher's exact test), Q value = 0.07
Table S276. Gene #69: '17p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 17P LOSS MUTATED | 15 | 11 | 10 | 30 | 9 |
| 17P LOSS WILD-TYPE | 132 | 87 | 49 | 98 | 47 |
Figure S276. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0225 (Fisher's exact test), Q value = 0.054
Table S277. Gene #69: '17p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 17P LOSS MUTATED | 3 | 23 | 11 | 15 |
| 17P LOSS WILD-TYPE | 59 | 83 | 49 | 75 |
Figure S277. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00062
Table S278. Gene #69: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 17P LOSS MUTATED | 5 | 1 | 15 | 19 | 2 | 10 |
| 17P LOSS WILD-TYPE | 65 | 40 | 25 | 63 | 23 | 50 |
Figure S278. Get High-res Image Gene #69: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S279. Gene #70: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 17Q LOSS MUTATED | 2 | 16 | 2 |
| 17Q LOSS WILD-TYPE | 271 | 118 | 83 |
Figure S279. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0101 (Fisher's exact test), Q value = 0.03
Table S280. Gene #70: '17q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 17Q LOSS MUTATED | 1 | 11 | 8 |
| 17Q LOSS WILD-TYPE | 159 | 154 | 159 |
Figure S280. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00092 (Fisher's exact test), Q value = 0.0048
Table S281. Gene #70: '17q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 17Q LOSS MUTATED | 0 | 7 | 13 |
| 17Q LOSS WILD-TYPE | 146 | 164 | 161 |
Figure S281. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0357 (Fisher's exact test), Q value = 0.076
Table S282. Gene #70: '17q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 17Q LOSS MUTATED | 2 | 11 | 7 |
| 17Q LOSS WILD-TYPE | 169 | 194 | 108 |
Figure S282. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0124 (Fisher's exact test), Q value = 0.035
Table S283. Gene #70: '17q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 17Q LOSS MUTATED | 1 | 8 | 11 |
| 17Q LOSS WILD-TYPE | 157 | 139 | 172 |
Figure S283. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.0452 (Fisher's exact test), Q value = 0.09
Table S284. Gene #70: '17q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 17Q LOSS MUTATED | 1 | 7 | 2 | 7 | 3 |
| 17Q LOSS WILD-TYPE | 146 | 91 | 57 | 121 | 53 |
Figure S284. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0306 (Fisher's exact test), Q value = 0.069
Table S285. Gene #70: '17q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 17Q LOSS MUTATED | 0 | 10 | 2 | 3 |
| 17Q LOSS WILD-TYPE | 62 | 96 | 58 | 87 |
Figure S285. Get High-res Image Gene #70: '17q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S286. Gene #71: '18p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 18P LOSS MUTATED | 21 | 43 | 4 |
| 18P LOSS WILD-TYPE | 252 | 91 | 81 |
Figure S286. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.005 (Fisher's exact test), Q value = 0.017
Table S287. Gene #71: '18p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 18P LOSS MUTATED | 11 | 29 | 28 |
| 18P LOSS WILD-TYPE | 149 | 136 | 139 |
Figure S287. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00325 (Fisher's exact test), Q value = 0.013
Table S288. Gene #71: '18p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 18P LOSS MUTATED | 9 | 30 | 29 |
| 18P LOSS WILD-TYPE | 137 | 141 | 145 |
Figure S288. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0491 (Fisher's exact test), Q value = 0.095
Table S289. Gene #71: '18p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 18P LOSS MUTATED | 15 | 35 | 18 |
| 18P LOSS WILD-TYPE | 156 | 170 | 97 |
Figure S289. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0299 (Fisher's exact test), Q value = 0.068
Table S290. Gene #71: '18p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 18P LOSS MUTATED | 15 | 7 | 12 | 24 | 9 |
| 18P LOSS WILD-TYPE | 132 | 91 | 47 | 104 | 47 |
Figure S290. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.03
Table S291. Gene #71: '18p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 18P LOSS MUTATED | 2 | 22 | 8 | 14 |
| 18P LOSS WILD-TYPE | 60 | 84 | 52 | 76 |
Figure S291. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.00567 (Fisher's exact test), Q value = 0.018
Table S292. Gene #71: '18p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 18P LOSS MUTATED | 5 | 2 | 11 | 17 | 1 | 10 |
| 18P LOSS WILD-TYPE | 65 | 39 | 29 | 65 | 24 | 50 |
Figure S292. Get High-res Image Gene #71: '18p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S293. Gene #72: '18q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 18Q LOSS MUTATED | 30 | 64 | 7 |
| 18Q LOSS WILD-TYPE | 243 | 70 | 78 |
Figure S293. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00629 (Fisher's exact test), Q value = 0.02
Table S294. Gene #72: '18q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| 18Q LOSS MUTATED | 20 | 39 | 42 |
| 18Q LOSS WILD-TYPE | 140 | 126 | 125 |
Figure S294. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00339 (Fisher's exact test), Q value = 0.013
Table S295. Gene #72: '18q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 18Q LOSS MUTATED | 17 | 39 | 45 |
| 18Q LOSS WILD-TYPE | 129 | 132 | 129 |
Figure S295. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0223 (Fisher's exact test), Q value = 0.054
Table S296. Gene #72: '18q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 18Q LOSS MUTATED | 24 | 47 | 30 |
| 18Q LOSS WILD-TYPE | 147 | 158 | 85 |
Figure S296. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0068 (Fisher's exact test), Q value = 0.021
Table S297. Gene #72: '18q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| 18Q LOSS MUTATED | 25 | 23 | 51 |
| 18Q LOSS WILD-TYPE | 133 | 124 | 132 |
Figure S297. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.0034 (Fisher's exact test), Q value = 0.013
Table S298. Gene #72: '18q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 18Q LOSS MUTATED | 21 | 12 | 17 | 37 | 12 |
| 18Q LOSS WILD-TYPE | 126 | 86 | 42 | 91 | 44 |
Figure S298. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0154 (Fisher's exact test), Q value = 0.04
Table S299. Gene #72: '18q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 18Q LOSS MUTATED | 6 | 32 | 11 | 19 |
| 18Q LOSS WILD-TYPE | 56 | 74 | 49 | 71 |
Figure S299. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S300. Gene #72: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 18Q LOSS MUTATED | 6 | 3 | 18 | 26 | 3 | 12 |
| 18Q LOSS WILD-TYPE | 64 | 38 | 22 | 56 | 22 | 48 |
Figure S300. Get High-res Image Gene #72: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.0014
Table S301. Gene #73: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 19P LOSS MUTATED | 2 | 11 | 4 |
| 19P LOSS WILD-TYPE | 271 | 123 | 81 |
Figure S301. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00292 (Fisher's exact test), Q value = 0.012
Table S302. Gene #73: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 19P LOSS MUTATED | 0 | 9 | 0 | 1 |
| 19P LOSS WILD-TYPE | 62 | 97 | 60 | 89 |
Figure S302. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0104 (Fisher's exact test), Q value = 0.031
Table S303. Gene #73: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 19P LOSS MUTATED | 0 | 0 | 1 | 8 | 0 | 1 |
| 19P LOSS WILD-TYPE | 70 | 41 | 39 | 74 | 25 | 59 |
Figure S303. Get High-res Image Gene #73: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0016
Table S304. Gene #74: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 19Q LOSS MUTATED | 2 | 11 | 4 |
| 19Q LOSS WILD-TYPE | 271 | 123 | 81 |
Figure S304. Get High-res Image Gene #74: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00294 (Fisher's exact test), Q value = 0.012
Table S305. Gene #74: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| 19Q LOSS MUTATED | 0 | 9 | 0 | 1 |
| 19Q LOSS WILD-TYPE | 62 | 97 | 60 | 89 |
Figure S305. Get High-res Image Gene #74: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 0.0104 (Fisher's exact test), Q value = 0.031
Table S306. Gene #74: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 19Q LOSS MUTATED | 0 | 0 | 1 | 8 | 0 | 1 |
| 19Q LOSS WILD-TYPE | 70 | 41 | 39 | 74 | 25 | 59 |
Figure S306. Get High-res Image Gene #74: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0383 (Fisher's exact test), Q value = 0.079
Table S307. Gene #75: '20p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 20P LOSS MUTATED | 8 | 10 | 1 |
| 20P LOSS WILD-TYPE | 265 | 124 | 84 |
Figure S307. Get High-res Image Gene #75: '20p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0271 (Fisher's exact test), Q value = 0.063
Table S308. Gene #76: '20q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 20Q LOSS MUTATED | 2 | 6 | 1 |
| 20Q LOSS WILD-TYPE | 271 | 128 | 84 |
Figure S308. Get High-res Image Gene #76: '20q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0381 (Fisher's exact test), Q value = 0.079
Table S309. Gene #76: '20q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 20Q LOSS MUTATED | 0 | 5 | 4 |
| 20Q LOSS WILD-TYPE | 171 | 200 | 111 |
Figure S309. Get High-res Image Gene #76: '20q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S310. Gene #77: '21q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 21Q LOSS MUTATED | 7 | 17 | 0 |
| 21Q LOSS WILD-TYPE | 266 | 117 | 85 |
Figure S310. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00361 (Fisher's exact test), Q value = 0.013
Table S311. Gene #77: '21q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 21Q LOSS MUTATED | 2 | 6 | 16 |
| 21Q LOSS WILD-TYPE | 144 | 165 | 158 |
Figure S311. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0404 (Fisher's exact test), Q value = 0.082
Table S312. Gene #77: '21q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 21Q LOSS MUTATED | 1 | 1 | 6 | 7 | 0 | 3 |
| 21Q LOSS WILD-TYPE | 69 | 40 | 34 | 75 | 25 | 57 |
Figure S312. Get High-res Image Gene #77: '21q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S313. Gene #78: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| 22Q LOSS MUTATED | 12 | 32 | 3 |
| 22Q LOSS WILD-TYPE | 261 | 102 | 82 |
Figure S313. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0187 (Fisher's exact test), Q value = 0.048
Table S314. Gene #78: '22q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| 22Q LOSS MUTATED | 6 | 20 | 21 |
| 22Q LOSS WILD-TYPE | 140 | 151 | 153 |
Figure S314. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 0.0475 (Fisher's exact test), Q value = 0.093
Table S315. Gene #78: '22q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| 22Q LOSS MUTATED | 9 | 25 | 13 |
| 22Q LOSS WILD-TYPE | 162 | 180 | 102 |
Figure S315. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0278 (Fisher's exact test), Q value = 0.064
Table S316. Gene #78: '22q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| 22Q LOSS MUTATED | 6 | 11 | 7 | 18 | 3 |
| 22Q LOSS WILD-TYPE | 141 | 87 | 52 | 110 | 53 |
Figure S316. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00024 (Fisher's exact test), Q value = 0.0016
Table S317. Gene #78: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 70 | 41 | 40 | 82 | 25 | 60 |
| 22Q LOSS MUTATED | 1 | 2 | 12 | 8 | 2 | 4 |
| 22Q LOSS WILD-TYPE | 69 | 39 | 28 | 74 | 23 | 56 |
Figure S317. Get High-res Image Gene #78: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S318. Gene #79: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| XP LOSS MUTATED | 7 | 29 | 3 |
| XP LOSS WILD-TYPE | 266 | 105 | 82 |
Figure S318. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S319. Gene #79: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| XP LOSS MUTATED | 1 | 20 | 18 |
| XP LOSS WILD-TYPE | 159 | 145 | 149 |
Figure S319. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0028
Table S320. Gene #79: 'xp loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| XP LOSS MUTATED | 2 | 17 | 20 |
| XP LOSS WILD-TYPE | 144 | 154 | 154 |
Figure S320. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00035
Table S321. Gene #79: 'xp loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| XP LOSS MUTATED | 2 | 24 | 13 |
| XP LOSS WILD-TYPE | 169 | 181 | 102 |
Figure S321. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S322. Gene #79: 'xp loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| XP LOSS MUTATED | 4 | 4 | 30 |
| XP LOSS WILD-TYPE | 154 | 143 | 153 |
Figure S322. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.0355 (Fisher's exact test), Q value = 0.076
Table S323. Gene #79: 'xp loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| XP LOSS MUTATED | 6 | 5 | 5 | 18 | 4 |
| XP LOSS WILD-TYPE | 141 | 93 | 54 | 110 | 52 |
Figure S323. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00556 (Fisher's exact test), Q value = 0.018
Table S324. Gene #79: 'xp loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| XP LOSS MUTATED | 0 | 12 | 1 | 7 |
| XP LOSS WILD-TYPE | 62 | 94 | 59 | 83 |
Figure S324. Get High-res Image Gene #79: 'xp loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S325. Gene #80: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 273 | 134 | 85 |
| XQ LOSS MUTATED | 7 | 29 | 3 |
| XQ LOSS WILD-TYPE | 266 | 105 | 82 |
Figure S325. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00019
Table S326. Gene #80: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 160 | 165 | 167 |
| XQ LOSS MUTATED | 1 | 20 | 18 |
| XQ LOSS WILD-TYPE | 159 | 145 | 149 |
Figure S326. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0025
Table S327. Gene #80: 'xq loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 146 | 171 | 174 |
| XQ LOSS MUTATED | 2 | 17 | 20 |
| XQ LOSS WILD-TYPE | 144 | 154 | 154 |
Figure S327. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #3: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00051
Table S328. Gene #80: 'xq loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 171 | 205 | 115 |
| XQ LOSS MUTATED | 2 | 24 | 13 |
| XQ LOSS WILD-TYPE | 169 | 181 | 102 |
Figure S328. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #4: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S329. Gene #80: 'xq loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 158 | 147 | 183 |
| XQ LOSS MUTATED | 4 | 4 | 30 |
| XQ LOSS WILD-TYPE | 154 | 143 | 153 |
Figure S329. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #5: 'MIRSEQ_CNMF'
P value = 0.0363 (Fisher's exact test), Q value = 0.076
Table S330. Gene #80: 'xq loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 147 | 98 | 59 | 128 | 56 |
| XQ LOSS MUTATED | 6 | 5 | 5 | 18 | 4 |
| XQ LOSS WILD-TYPE | 141 | 93 | 54 | 110 | 52 |
Figure S330. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #6: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00548 (Fisher's exact test), Q value = 0.018
Table S331. Gene #80: 'xq loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 106 | 60 | 90 |
| XQ LOSS MUTATED | 0 | 12 | 1 | 7 |
| XQ LOSS WILD-TYPE | 62 | 94 | 59 | 83 |
Figure S331. Get High-res Image Gene #80: 'xq loss' versus Molecular Subtype #7: 'MIRSEQ_MATURE_CNMF'
-
Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/PRAD-TP/15098599/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/PRAD-TP/15115159/PRAD-TP.transferedmergedcluster.txt
-
Number of patients = 492
-
Number of significantly arm-level cnvs = 80
-
Number of molecular subtypes = 8
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Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.