Correlation between copy number variation genes (focal events) and selected clinical features
Overview
Introduction

This pipeline computes the correlation between significant copy number variation (cnv focal) genes and selected clinical features.

Summary

Testing the association between copy number variation 65 focal events and 14 clinical features across 482 patients, 519 significant findings detected with Q value < 0.25.

  • amp_1q22 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_3q21.3 cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_3q26.2 cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_4p16.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_4q13.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_5q35.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_7p14.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_7q22.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY', and 'GLEASON_SCORE'.

  • amp_8p11.23 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_8q22.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_8q24.21 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_9q33.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_11q13.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY', and 'GLEASON_SCORE'.

  • amp_12q23.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_13q12.11 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY', and 'GLEASON_SCORE'.

  • amp_14q21.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY', and 'GLEASON_SCORE'.

  • amp_15q11.2 cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY', and 'GLEASON_SCORE'.

  • amp_16q11.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_17q23.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_VALUE'.

  • amp_19q13.43 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_20q13.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_xp22.11 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY', and 'GLEASON_SCORE'.

  • amp_xp22.11 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • amp_xp21.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP',  'PSA_VALUE', and 'RACE'.

  • amp_xq21.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • amp_xq21.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'RACE'.

  • amp_xq25 cnv correlated to 'PATHOLOGY_T_STAGE',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'RACE'.

  • amp_xq27.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE', and 'GLEASON_SCORE'.

  • del_1p31.3 cnv correlated to 'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_VALUE'.

  • del_1p22.1 cnv correlated to 'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_1q23.1 cnv correlated to 'YEARS_TO_BIRTH'.

  • del_1q42.3 cnv correlated to 'Time to Death',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_VALUE'.

  • del_2p21 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY', and 'GLEASON_SCORE'.

  • del_2q22.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY', and 'GLEASON_SCORE'.

  • del_2q22.3 cnv correlated to 'YEARS_TO_BIRTH',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_VALUE'.

  • del_3p13 cnv correlated to 'YEARS_TO_BIRTH'.

  • del_3q29 cnv correlated to 'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_4q28.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY', and 'GLEASON_SCORE'.

  • del_5q11.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_5q13.2 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_5q21.1 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • del_6p25.1 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'RACE'.

  • del_6q14.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_7q31.33 cnv correlated to 'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_PRIMARY', and 'GLEASON_SCORE'.

  • del_8p23.2 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • del_8p21.3 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • del_9p23 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY', and 'GLEASON_SCORE'.

  • del_10q23.31 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_VALUE'.

  • del_11p11.2 cnv correlated to 'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'RACE'.

  • del_11q22.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_11q23.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_12p13.1 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'HISTOLOGICAL_TYPE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • del_12q24.32 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE', and 'PSA_RESULT_PREOP'.

  • del_13q14.13 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'RACE'.

  • del_13q22.1 cnv correlated to 'Time to Death',  'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'RACE'.

  • del_15q21.3 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_VALUE'.

  • del_16q22.3 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • del_16q24.1 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE',  'PSA_RESULT_PREOP', and 'PSA_VALUE'.

  • del_17p13.1 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY', and 'GLEASON_SCORE'.

  • del_17q21.31 cnv correlated to 'PATHOLOGY_T_STAGE'.

  • del_18q21.31 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY', and 'GLEASON_SCORE'.

  • del_18q23 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'COMPLETENESS_OF_RESECTION',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'PSA_VALUE'.

  • del_19q13.2 cnv correlated to 'YEARS_TO_BIRTH',  'PATHOLOGY_T_STAGE',  'COMPLETENESS_OF_RESECTION',  'GLEASON_SCORE_COMBINED',  'GLEASON_SCORE_PRIMARY', and 'GLEASON_SCORE'.

  • del_21q22.2 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_SECONDARY',  'GLEASON_SCORE', and 'RACE'.

  • del_21q22.3 cnv correlated to 'PATHOLOGY_T_STAGE',  'PATHOLOGY_N_STAGE',  'NUMBER_OF_LYMPH_NODES',  'GLEASON_SCORE_SECONDARY', and 'RACE'.

Results
Overview of the results

Table 1.  Get Full Table Overview of the association between significant copy number variation of 65 focal events and 14 clinical features. Shown in the table are P values (Q values). Thresholded by Q value < 0.25, 519 significant findings detected.

Clinical
Features 		Time
to
Death 		YEARS
TO
BIRTH 		PATHOLOGY
T
STAGE 		PATHOLOGY
N
STAGE 		HISTOLOGICAL
TYPE 		COMPLETENESS
OF
RESECTION 		NUMBER
OF
LYMPH
NODES 		GLEASON
SCORE
COMBINED 		GLEASON
SCORE
PRIMARY 		GLEASON
SCORE
SECONDARY 		GLEASON
SCORE 		PSA
RESULT
PREOP 		PSA
VALUE 		RACE
nCNV (%) nWild-Type logrank test Wilcoxon-test Fisher's exact test Fisher's exact test Fisher's exact test Fisher's exact test Wilcoxon-test Wilcoxon-test Wilcoxon-test Wilcoxon-test Wilcoxon-test Wilcoxon-test Wilcoxon-test Fisher's exact test
amp 3q21 3 72 (15%) 410 0.0647
(0.136) 		0.00296
(0.0111) 		1e-05
(0.000117) 		0.00312
(0.0116) 		0.142
(0.249) 		0.00025
(0.00167) 		0.000214
(0.00149) 		1.73e-08
(5.98e-07) 		1.11e-07
(2.9e-06) 		0.00143
(0.00656) 		2.01e-11
(2.29e-09) 		1.24e-05
(0.000143) 		0.109
(0.203) 		0.657
(0.772)
amp 1q22 38 (8%) 444 0.442
(0.587) 		0.00684
(0.022) 		1e-05
(0.000117) 		0.0019
(0.00784) 		0.0186
(0.0506) 		0.032
(0.0771) 		0.000436
(0.00265) 		9.55e-06
(0.000117) 		5.7e-06
(9.11e-05) 		0.0538
(0.119) 		3.64e-07
(7.88e-06) 		0.0321
(0.0771) 		0.111
(0.207) 		1
(1.00)
amp 3q26 2 83 (17%) 399 0.0688
(0.143) 		0.0252
(0.0638) 		1e-05
(0.000117) 		0.00105
(0.0051) 		0.276
(0.422) 		0.00013
(0.001) 		0.000111
(0.000899) 		3.26e-08
(9.26e-07) 		5.48e-08
(1.47e-06) 		0.00494
(0.0165) 		6.66e-10
(4.66e-08) 		0.000121
(0.000957) 		0.0407
(0.0931) 		1
(1.00)
amp xp21 1 22 (5%) 460 0.579
(0.711) 		0.00191
(0.00784) 		0.00528
(0.0174) 		0.0936
(0.18) 		0.0217
(0.0574) 		0.0241
(0.0621) 		0.0974
(0.186) 		0.00152
(0.00687) 		0.000124
(0.000971) 		0.625
(0.752) 		0.000344
(0.00222) 		0.0713
(0.147) 		0.0902
(0.175) 		0.00762
(0.0242)
amp 8q22 1 152 (32%) 330 0.971
(1.00) 		0.0747
(0.152) 		1e-05
(0.000117) 		0.00315
(0.0116) 		0.564
(0.698) 		1e-05
(0.000117) 		0.00114
(0.00546) 		1.69e-11
(2.19e-09) 		4.49e-12
(1.02e-09) 		0.00293
(0.011) 		5.87e-13
(4.67e-10) 		0.000526
(0.00292) 		0.0542
(0.119) 		1
(1.00)
amp 8q24 21 148 (31%) 334 0.513
(0.653) 		0.0512
(0.114) 		1e-05
(0.000117) 		0.000675
(0.00355) 		0.566
(0.699) 		8e-05
(0.000668) 		0.000179
(0.0013) 		1.06e-11
(1.61e-09) 		1.03e-12
(4.67e-10) 		0.00248
(0.00964) 		1.68e-12
(5.09e-10) 		0.000354
(0.00225) 		0.0374
(0.0876) 		0.814
(0.902)
amp 9q33 3 58 (12%) 424 0.362
(0.517) 		0.0179
(0.0491) 		1e-05
(0.000117) 		1.78e-08
(5.98e-07) 		0.0751
(0.152) 		0.00179
(0.00758) 		3.7e-10
(3.37e-08) 		1.91e-10
(1.93e-08) 		4.98e-10
(3.77e-08) 		0.000403
(0.00251) 		9.99e-12
(1.61e-09) 		0.000782
(0.00398) 		0.418
(0.57) 		0.556
(0.691)
amp 16q11 2 29 (6%) 453 0.539
(0.677) 		0.0309
(0.0754) 		0.00044
(0.00265) 		0.122
(0.223) 		0.203
(0.333) 		0.0552
(0.121) 		0.115
(0.212) 		1.85e-05
(0.000198) 		0.000995
(0.00489) 		0.0027
(0.0104) 		2.14e-06
(3.74e-05) 		0.00442
(0.0151) 		0.0148
(0.0423) 		1
(1.00)
del 13q22 1 169 (35%) 313 0.109
(0.203) 		0.00109
(0.00525) 		0.00019
(0.00137) 		0.147
(0.256) 		0.397
(0.551) 		0.02
(0.0541) 		0.0514
(0.115) 		1.52e-07
(3.72e-06) 		4.39e-06
(7.13e-05) 		0.0022
(0.0087) 		2.27e-09
(1.48e-07) 		0.0312
(0.0759) 		0.26
(0.404) 		0.00045
(0.00265)
del 16q22 3 185 (38%) 297 0.458
(0.602) 		0.0627
(0.134) 		0.00035
(0.00224) 		0.0273
(0.0683) 		1
(1.00) 		0.0702
(0.146) 		0.0104
(0.0318) 		1.34e-08
(5.53e-07) 		1.55e-07
(3.72e-06) 		0.00139
(0.00645) 		5.69e-09
(2.88e-07) 		0.00202
(0.00812) 		0.0877
(0.171) 		0.717
(0.821)
amp 4q13 3 22 (5%) 460 0.539
(0.677) 		0.0163
(0.0455) 		0.00149
(0.00675) 		0.000462
(0.00268) 		0.485
(0.624) 		0.00398
(0.0139) 		4.53e-05
(0.000413) 		5.42e-05
(0.000483) 		2.65e-05
(0.000271) 		0.0537
(0.119) 		0.000173
(0.00128) 		0.00483
(0.0162) 		0.393
(0.548) 		1
(1.00)
amp 15q11 2 15 (3%) 467 0.0829
(0.164) 		0.0774
(0.155) 		0.118
(0.218) 		0.000129
(0.001) 		1
(1.00) 		0.0285
(0.0705) 		3.85e-06
(6.49e-05) 		0.00207
(0.00821) 		0.00104
(0.00508) 		0.134
(0.236) 		0.00235
(0.00918) 		0.661
(0.773) 		0.609
(0.74)
amp 17q23 2 24 (5%) 458 0.671
(0.782) 		0.122
(0.223) 		0.00072
(0.00374) 		0.0212
(0.0566) 		0.0275
(0.0685) 		0.17
(0.288) 		0.0104
(0.0316) 		0.00201
(0.00812) 		0.00178
(0.00755) 		0.0642
(0.136) 		0.000166
(0.00124) 		0.475
(0.617) 		0.113
(0.209) 		1
(1.00)
amp 19q13 43 17 (4%) 465 0.556
(0.691) 		0.0175
(0.0484) 		0.0004
(0.00251) 		0.0206
(0.0554) 		0.0831
(0.164) 		0.207
(0.339) 		0.0108
(0.0326) 		0.000859
(0.00427) 		0.000468
(0.00269) 		0.124
(0.224) 		2.77e-05
(0.00028) 		0.0342
(0.0816) 		0.745
(0.84) 		1
(1.00)
amp 20q13 2 42 (9%) 440 0.4
(0.554) 		0.0019
(0.00784) 		5e-05
(0.00045) 		0.0153
(0.0435) 		0.349
(0.503) 		0.00973
(0.03) 		0.00736
(0.0235) 		0.000216
(0.00149) 		1.36e-05
(0.000151) 		0.213
(0.347) 		6.14e-07
(1.22e-05) 		0.0789
(0.157) 		0.0805
(0.16) 		1
(1.00)
amp xp22 11 23 (5%) 459 0.613
(0.742) 		0.0943
(0.181) 		0.00197
(0.008) 		0.158
(0.272) 		0.0245
(0.0623) 		0.0242
(0.0622) 		0.128
(0.23) 		0.000818
(0.00413) 		6.16e-05
(0.000534) 		0.447
(0.591) 		0.00169
(0.00735) 		0.073
(0.149) 		0.0781
(0.156) 		0.217
(0.351)
amp xq21 1 13 (3%) 469 0.624
(0.751) 		0.0215
(0.057) 		0.0239
(0.0619) 		0.0671
(0.14) 		1
(1.00) 		0.0906
(0.175) 		0.0682
(0.142) 		0.0375
(0.0876) 		0.0349
(0.0828) 		0.427
(0.576) 		0.00375
(0.0134) 		0.0117
(0.0349) 		0.3
(0.45) 		0.0268
(0.0679)
del 5q11 2 96 (20%) 386 0.977
(1.00) 		0.0203
(0.0547) 		1e-05
(0.000117) 		0.000294
(0.00195) 		0.746
(0.84) 		0.0298
(0.0731) 		7.85e-06
(0.000117) 		1.58e-08
(5.91e-07) 		1.49e-08
(5.91e-07) 		0.0125
(0.037) 		4.43e-10
(3.67e-08) 		0.00044
(0.00265) 		0.681
(0.791) 		0.441
(0.587)
del 11q22 3 43 (9%) 439 0.415
(0.569) 		0.027
(0.068) 		0.00045
(0.00265) 		0.118
(0.218) 		0.36
(0.515) 		0.00287
(0.0109) 		0.0639
(0.135) 		6.77e-06
(0.000104) 		2.1e-06
(3.74e-05) 		0.0516
(0.115) 		3.74e-05
(0.000361) 		0.013
(0.0379) 		0.843
(0.927) 		0.635
(0.759)
del 12p13 1 122 (25%) 360 0.542
(0.678) 		0.755
(0.849) 		1e-05
(0.000117) 		0.0153
(0.0435) 		0.13
(0.231) 		0.248
(0.392) 		0.00453
(0.0153) 		3.09e-05
(0.000306) 		6.06e-05
(0.000531) 		0.0122
(0.0363) 		1.73e-05
(0.000188) 		0.0242
(0.0622) 		0.0177
(0.0487) 		1
(1.00)
del 18q23 132 (27%) 350 0.711
(0.816) 		0.108
(0.202) 		0.00047
(0.00269) 		0.00469
(0.0158) 		1
(1.00) 		0.00441
(0.0151) 		0.00235
(0.00918) 		2.53e-05
(0.000261) 		0.000573
(0.00312) 		0.00322
(0.0118) 		2.51e-06
(4.31e-05) 		0.438
(0.585) 		0.0533
(0.118) 		0.445
(0.588)
amp 5q35 3 28 (6%) 454 0.473
(0.617) 		1.71e-07
(3.85e-06) 		0.0002
(0.00143) 		0.000632
(0.00336) 		0.572
(0.705) 		0.0572
(0.124) 		5.53e-05
(0.000488) 		0.00283
(0.0108) 		0.000514
(0.00291) 		0.342
(0.498) 		2.1e-05
(0.000222) 		0.034
(0.0815) 		0.908
(0.983) 		0.262
(0.404)
amp 11q13 2 46 (10%) 436 0.448
(0.591) 		0.000571
(0.00312) 		4e-05
(0.000375) 		1.55e-05
(0.000169) 		0.634
(0.759) 		0.00389
(0.0138) 		8.3e-07
(1.57e-05) 		4.44e-08
(1.23e-06) 		6.53e-09
(2.97e-07) 		0.0406
(0.0931) 		2.2e-08
(7.17e-07) 		0.167
(0.284) 		0.554
(0.691) 		0.348
(0.503)
amp 12q23 1 36 (7%) 446 0.406
(0.561) 		0.0988
(0.188) 		0.00061
(0.00327) 		0.000175
(0.00128) 		1
(1.00) 		0.00014
(0.00105) 		2.37e-05
(0.000248) 		1.32e-05
(0.000148) 		1.16e-07
(2.93e-06) 		0.353
(0.508) 		5.05e-07
(1.02e-05) 		8.68e-05
(0.000718) 		0.393
(0.548) 		1
(1.00)
del 2p21 45 (9%) 437 0.951
(1.00) 		0.126
(0.227) 		0.00042
(0.0026) 		0.0371
(0.0874) 		0.631
(0.756) 		0.0418
(0.0954) 		0.0508
(0.114) 		0.00188
(0.00784) 		0.00328
(0.0119) 		0.075
(0.152) 		0.00185
(0.0078) 		0.531
(0.668) 		0.248
(0.392) 		1
(1.00)
del 6q14 3 173 (36%) 309 0.513
(0.653) 		0.00204
(0.00814) 		0.0733
(0.15) 		0.0243
(0.0622) 		1
(1.00) 		0.00033
(0.00216) 		0.0154
(0.0436) 		0.000745
(0.00383) 		0.000428
(0.00263) 		0.214
(0.348) 		0.000668
(0.00353) 		0.0052
(0.0172) 		0.637
(0.76) 		0.583
(0.713)
del 8p21 3 286 (59%) 196 0.624
(0.751) 		0.375
(0.531) 		1e-05
(0.000117) 		0.00158
(0.007) 		0.583
(0.713) 		0.137
(0.241) 		0.00092
(0.00455) 		0.000213
(0.00149) 		6.83e-06
(0.000104) 		0.344
(0.499) 		0.00168
(0.00735) 		0.000112
(0.000899) 		0.0705
(0.146) 		0.728
(0.831)
del 13q14 13 221 (46%) 261 0.646
(0.765) 		0.0107
(0.0325) 		0.00535
(0.0176) 		0.202
(0.332) 		0.277
(0.422) 		0.00192
(0.00784) 		0.16
(0.274) 		3.77e-05
(0.000361) 		7.16e-05
(0.000613) 		0.0837
(0.165) 		3.58e-05
(0.00035) 		0.00775
(0.0245) 		0.327
(0.479) 		0.00396
(0.0139)
del 16q24 1 206 (43%) 276 0.176
(0.295) 		0.306
(0.455) 		1e-05
(0.000117) 		0.0402
(0.0924) 		1
(1.00) 		0.204
(0.333) 		0.0203
(0.0547) 		6.08e-09
(2.91e-07) 		3.39e-09
(2.06e-07) 		0.01
(0.0308) 		5.24e-09
(2.88e-07) 		0.000573
(0.00312) 		0.09
(0.175) 		1
(1.00)
amp 7p14 3 101 (21%) 381 0.692
(0.801) 		0.0078
(0.0246) 		0.0223
(0.0583) 		0.641
(0.762) 		0.744
(0.84) 		0.00126
(0.00591) 		0.482
(0.622) 		0.00173
(0.0074) 		0.00439
(0.0151) 		0.0358
(0.0847) 		0.000244
(0.00164) 		0.0781
(0.156) 		0.912
(0.986) 		1
(1.00)
amp 8p11 23 66 (14%) 416 0.198
(0.326) 		0.000452
(0.00265) 		0.00439
(0.0151) 		0.475
(0.617) 		0.704
(0.812) 		0.0135
(0.0392) 		0.371
(0.527) 		6.33e-06
(9.93e-05) 		4.92e-07
(1.02e-05) 		0.119
(0.218) 		1.43e-06
(2.65e-05) 		0.00432
(0.015) 		0.785
(0.872) 		1
(1.00)
amp 13q12 11 25 (5%) 457 0.395
(0.549) 		0.000321
(0.00212) 		0.00421
(0.0146) 		0.0936
(0.18) 		0.0307
(0.0752) 		0.168
(0.286) 		0.0796
(0.158) 		0.0236
(0.0611) 		0.00321
(0.0118) 		0.723
(0.827) 		0.0079
(0.0248) 		0.28
(0.425) 		0.442
(0.587) 		0.305
(0.455)
amp 14q21 1 27 (6%) 455 0.166
(0.284) 		0.0223
(0.0583) 		0.132
(0.234) 		0.0477
(0.107) 		0.182
(0.303) 		0.583
(0.713) 		0.0224
(0.0583) 		0.00742
(0.0236) 		0.0278
(0.0689) 		0.101
(0.191) 		0.000491
(0.00279) 		0.258
(0.403) 		0.881
(0.96) 		1
(1.00)
del 1p31 3 57 (12%) 425 0.465
(0.609) 		0.225
(0.362) 		0.0126
(0.0372) 		0.173
(0.29) 		0.39
(0.547) 		0.0615
(0.131) 		0.131
(0.233) 		0.000458
(0.00267) 		0.0214
(0.057) 		0.0016
(0.00706) 		0.000382
(0.00241) 		0.874
(0.957) 		0.131
(0.233) 		0.197
(0.325)
del 1p22 1 55 (11%) 427 0.298
(0.449) 		0.473
(0.617) 		0.0035
(0.0126) 		0.173
(0.29) 		0.386
(0.543) 		0.0885
(0.172) 		0.06
(0.129) 		0.00337
(0.0122) 		0.00493
(0.0165) 		0.122
(0.223) 		0.000608
(0.00327) 		0.00406
(0.0142) 		0.889
(0.967) 		1
(1.00)
del 5q13 2 96 (20%) 386 0.715
(0.819) 		0.265
(0.408) 		1e-05
(0.000117) 		0.0132
(0.0385) 		0.746
(0.84) 		0.242
(0.384) 		0.00172
(0.0074) 		2.49e-08
(7.32e-07) 		1.74e-07
(3.85e-06) 		0.00289
(0.0109) 		1.62e-08
(5.91e-07) 		0.00373
(0.0134) 		0.517
(0.655) 		0.293
(0.443)
del 6p25 1 41 (9%) 441 0.652
(0.769) 		0.513
(0.653) 		0.017
(0.0471) 		0.00802
(0.0251) 		1
(1.00) 		0.659
(0.773) 		0.00158
(0.007) 		0.000136
(0.00103) 		0.00172
(0.0074) 		0.0177
(0.0487) 		8.95e-05
(0.000734) 		0.522
(0.659) 		0.25
(0.394) 		0.00661
(0.0214)
del 8p23 2 218 (45%) 264 0.65
(0.768) 		0.436
(0.584) 		1e-05
(0.000117) 		0.0103
(0.0314) 		1
(1.00) 		0.431
(0.58) 		0.00502
(0.0167) 		0.00146
(0.00665) 		7.83e-05
(0.000659) 		0.398
(0.552) 		0.00453
(0.0153) 		0.027
(0.068) 		0.0964
(0.185) 		0.377
(0.533)
del 10q23 31 152 (32%) 330 0.64
(0.762) 		0.415
(0.569) 		1e-05
(0.000117) 		0.00305
(0.0113) 		0.773
(0.862) 		0.165
(0.282) 		0.00115
(0.0055) 		4.15e-06
(6.87e-05) 		0.000444
(0.00265) 		0.00102
(0.005) 		1.72e-07
(3.85e-06) 		0.315
(0.465) 		0.0115
(0.0343) 		0.236
(0.377)
del 11q23 2 48 (10%) 434 0.418
(0.57) 		0.0568
(0.124) 		0.00204
(0.00814) 		0.671
(0.782) 		1
(1.00) 		0.0114
(0.0343) 		0.827
(0.911) 		4e-05
(0.000375) 		0.000221
(0.00151) 		0.0221
(0.0583) 		4.46e-05
(0.00041) 		0.104
(0.196) 		0.496
(0.635) 		0.657
(0.772)
del 15q21 3 66 (14%) 416 0.295
(0.445) 		0.251
(0.394) 		1e-05
(0.000117) 		0.0014
(0.00647) 		0.421
(0.573) 		0.154
(0.266) 		0.000522
(0.00292) 		2.29e-08
(7.18e-07) 		4.67e-07
(9.89e-06) 		0.00073
(0.00377) 		5.67e-09
(2.88e-07) 		0.879
(0.96) 		0.121
(0.223) 		1
(1.00)
del 17p13 1 154 (32%) 328 0.846
(0.928) 		0.578
(0.71) 		3e-05
(3e-04) 		0.00668
(0.0216) 		0.775
(0.863) 		0.0448
(0.102) 		0.000689
(0.0036) 		8.2e-09
(3.55e-07) 		6.94e-07
(1.34e-05) 		0.000207
(0.00147) 		2.41e-08
(7.32e-07) 		0.992
(1.00) 		0.185
(0.307) 		0.822
(0.909)
del 18q21 31 126 (26%) 356 0.641
(0.762) 		0.66
(0.773) 		0.0006
(0.00325) 		0.0222
(0.0583) 		1
(1.00) 		0.0013
(0.00607) 		0.0146
(0.0419) 		7.2e-05
(0.000613) 		0.00169
(0.00735) 		0.00393
(0.0139) 		1.26e-05
(0.000144) 		0.26
(0.404) 		0.357
(0.512) 		0.392
(0.548)
amp 7q22 1 98 (20%) 384 0.698
(0.806) 		0.00591
(0.0193) 		0.0707
(0.146) 		0.875
(0.957) 		1
(1.00) 		0.00255
(0.00987) 		0.743
(0.84) 		0.00188
(0.00784) 		0.00276
(0.0105) 		0.0555
(0.121) 		0.000226
(0.00154) 		0.411
(0.565) 		0.519
(0.656) 		1
(1.00)
amp xp22 11 24 (5%) 458 0.641
(0.762) 		0.016
(0.045) 		0.00268
(0.0103) 		0.17
(0.288) 		0.0275
(0.0685) 		0.0245
(0.0623) 		0.165
(0.282) 		0.00154
(0.00691) 		0.000215
(0.00149) 		0.424
(0.575) 		0.00141
(0.00647) 		0.444
(0.588) 		0.271
(0.415) 		0.261
(0.404)
del 1q42 3 46 (10%) 436 0.000113
(0.000899) 		0.15
(0.26) 		0.31
(0.46) 		0.217
(0.351) 		1
(1.00) 		0.0127
(0.0373) 		0.106
(0.2) 		0.128
(0.229) 		0.0315
(0.0763) 		0.938
(1.00) 		0.0572
(0.124) 		0.299
(0.449) 		0.0826
(0.163) 		0.555
(0.691)
del 5q21 1 105 (22%) 377 0.992
(1.00) 		0.0402
(0.0924) 		0.0288
(0.0709) 		0.764
(0.856) 		0.744
(0.84) 		0.481
(0.622) 		0.558
(0.692) 		0.000134
(0.00102) 		2.01e-06
(3.67e-05) 		0.486
(0.624) 		0.00292
(0.011) 		0.0636
(0.135) 		0.127
(0.228) 		0.735
(0.837)
del 11p11 2 34 (7%) 448 0.462
(0.606) 		0.467
(0.611) 		0.0146
(0.0419) 		0.474
(0.617) 		0.613
(0.742) 		0.0372
(0.0876) 		0.317
(0.467) 		0.0214
(0.057) 		0.0155
(0.0438) 		0.364
(0.52) 		0.00839
(0.0261) 		0.11
(0.204) 		0.618
(0.746) 		0.00387
(0.0138)
del 12q24 32 42 (9%) 440 0.731
(0.834) 		0.939
(1.00) 		0.0039
(0.0138) 		0.0468
(0.106) 		1
(1.00) 		0.307
(0.457) 		0.0286
(0.0706) 		0.0585
(0.127) 		0.0747
(0.152) 		0.229
(0.367) 		0.0615
(0.131) 		0.0129
(0.0379) 		0.906
(0.983) 		1
(1.00)
amp 4p16 3 19 (4%) 463 0.542
(0.678) 		0.0393
(0.091) 		0.00083
(0.00415) 		0.343
(0.498) 		0.435
(0.583) 		0.212
(0.346) 		0.335
(0.488) 		0.0274
(0.0684) 		0.00708
(0.0227) 		0.595
(0.724) 		0.0063
(0.0205) 		0.0106
(0.0322) 		0.391
(0.547) 		1
(1.00)
amp xq21 1 15 (3%) 467 0.606
(0.737) 		0.0763
(0.154) 		0.0377
(0.0878) 		0.491
(0.63) 		1
(1.00) 		0.144
(0.252) 		0.424
(0.575) 		0.0972
(0.186) 		0.0661
(0.139) 		0.645
(0.764) 		0.00944
(0.0292) 		0.0376
(0.0877) 		0.37
(0.526) 		0.346
(0.501)
del 9p23 43 (9%) 439 0.302
(0.452) 		0.492
(0.631) 		0.0314
(0.0763) 		0.0845
(0.166) 		1
(1.00) 		0.422
(0.574) 		0.032
(0.0771) 		0.0162
(0.0455) 		0.0136
(0.0392) 		0.27
(0.415) 		0.00811
(0.0253) 		0.824
(0.91) 		0.179
(0.299) 		1
(1.00)
del 19q13 2 49 (10%) 433 0.567
(0.7) 		0.0343
(0.0818) 		0.0063
(0.0205) 		0.318
(0.468) 		1
(1.00) 		0.0721
(0.148) 		0.308
(0.457) 		0.000335
(0.00218) 		4.38e-05
(0.000407) 		0.152
(0.264) 		0.00123
(0.00582) 		1
(1.00) 		0.241
(0.383) 		1
(1.00)
del 21q22 2 50 (10%) 432 0.428
(0.576) 		0.217
(0.351) 		0.0023
(0.00906) 		0.101
(0.192) 		0.169
(0.286) 		0.745
(0.84) 		0.061
(0.131) 		0.15
(0.26) 		0.611
(0.741) 		0.064
(0.135) 		0.0575
(0.125) 		0.688
(0.798) 		0.365
(0.52) 		0.0773
(0.155)
amp xq25 17 (4%) 465 0.584
(0.713) 		0.289
(0.438) 		0.0594
(0.128) 		0.526
(0.662) 		1
(1.00) 		0.16
(0.274) 		0.669
(0.782) 		0.0388
(0.09) 		0.108
(0.202) 		0.225
(0.362) 		0.0232
(0.0604) 		0.482
(0.622) 		0.25
(0.394) 		0.0188
(0.0512)
del 2q22 1 90 (19%) 392 0.829
(0.912) 		8.44e-06
(0.000117) 		0.125
(0.226) 		1
(1.00) 		0.484
(0.624) 		0.251
(0.394) 		0.905
(0.982) 		0.0144
(0.0415) 		0.000754
(0.00385) 		0.819
(0.907) 		0.0133
(0.0386) 		0.561
(0.695) 		0.262
(0.404) 		0.416
(0.569)
del 4q28 2 49 (10%) 433 0.407
(0.562) 		0.00192
(0.00784) 		0.0668
(0.14) 		0.41
(0.565) 		0.644
(0.764) 		0.388
(0.545) 		0.316
(0.466) 		0.00116
(0.00551) 		0.000821
(0.00413) 		0.19
(0.315) 		0.000524
(0.00292) 		0.954
(1.00) 		0.709
(0.815) 		0.301
(0.452)
del 21q22 3 145 (30%) 337 0.377
(0.533) 		0.195
(0.323) 		0.0437
(0.0995) 		0.128
(0.229) 		0.768
(0.858) 		0.759
(0.852) 		0.0491
(0.11) 		0.229
(0.367) 		0.651
(0.768) 		0.0872
(0.17) 		0.158
(0.273) 		0.44
(0.587) 		0.421
(0.573) 		0.131
(0.233)
del 2q22 3 83 (17%) 399 0.776
(0.864) 		0.00173
(0.0074) 		0.457
(0.602) 		0.616
(0.744) 		0.481
(0.622) 		0.505
(0.644) 		0.469
(0.613) 		0.185
(0.307) 		0.0167
(0.0466) 		0.789
(0.875) 		0.1
(0.191) 		0.272
(0.417) 		0.14
(0.246) 		1
(1.00)
del 3q29 32 (7%) 450 0.496
(0.635) 		0.692
(0.801) 		0.214
(0.347) 		0.235
(0.376) 		0.236
(0.377) 		0.173
(0.29) 		0.262
(0.404) 		0.0541
(0.119) 		0.0448
(0.102) 		0.519
(0.656) 		0.0853
(0.167) 		0.0812
(0.161) 		0.881
(0.96) 		1
(1.00)
del 7q31 33 28 (6%) 454 0.737
(0.839) 		0.279
(0.425) 		0.384
(0.542) 		0.102
(0.193) 		1
(1.00) 		0.9
(0.979) 		0.0348
(0.0827) 		0.154
(0.266) 		0.122
(0.223) 		0.627
(0.753) 		0.0729
(0.149) 		0.999
(1.00) 		0.856
(0.939) 		1
(1.00)
amp xq27 1 17 (4%) 465 0.672
(0.782) 		0.0185
(0.0505) 		0.0679
(0.142) 		1
(1.00) 		1
(1.00) 		0.172
(0.289) 		0.979
(1.00) 		0.41
(0.565) 		0.353
(0.508) 		0.914
(0.986) 		0.134
(0.236) 		0.572
(0.705) 		0.191
(0.317) 		0.425
(0.575)
del 1q23 1 28 (6%) 454 0.335
(0.488) 		0.123
(0.223) 		0.385
(0.543) 		1
(1.00) 		1
(1.00) 		0.515
(0.654) 		0.826
(0.911) 		0.145
(0.253) 		0.312
(0.462) 		0.294
(0.444) 		0.908
(0.983) 		0.706
(0.813) 		0.926
(0.998) 		1
(1.00)
del 3p13 77 (16%) 405 0.656
(0.772) 		0.04
(0.0924) 		0.935
(1.00) 		0.304
(0.455) 		0.255
(0.399) 		0.344
(0.499) 		0.274
(0.419) 		0.586
(0.715) 		0.435
(0.583) 		0.934
(1.00) 		0.328
(0.481) 		0.543
(0.679) 		0.688
(0.798) 		1
(1.00)
del 17q21 31 93 (19%) 389 0.264
(0.408) 		0.354
(0.509) 		0.125
(0.225) 		0.747
(0.84) 		0.739
(0.84) 		0.958
(1.00) 		0.71
(0.815) 		0.246
(0.39) 		0.258
(0.403) 		0.443
(0.587) 		0.331
(0.484) 		0.434
(0.583) 		0.773
(0.862) 		0.762
(0.854)
'amp_1q22' versus 'YEARS_TO_BIRTH'

P value = 0.00684 (Wilcoxon-test), Q value = 0.022

Table S1.  Gene #1: 'amp_1q22' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 1(1Q22) MUTATED 36 63.7 (4.5)
AMP PEAK 1(1Q22) WILD-TYPE 435 60.7 (6.9)

Figure S1.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_1q22' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S2.  Gene #1: 'amp_1q22' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 1(1Q22) MUTATED 4 29 5
AMP PEAK 1(1Q22) WILD-TYPE 184 252 5

Figure S2.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_1q22' versus 'PATHOLOGY_N_STAGE'

P value = 0.0019 (Fisher's exact test), Q value = 0.0078

Table S3.  Gene #1: 'amp_1q22' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 1(1Q22) MUTATED 21 14
AMP PEAK 1(1Q22) WILD-TYPE 317 61

Figure S3.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_1q22' versus 'HISTOLOGICAL_TYPE'

P value = 0.0186 (Fisher's exact test), Q value = 0.051

Table S4.  Gene #1: 'amp_1q22' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 1(1Q22) MUTATED 4 34
AMP PEAK 1(1Q22) WILD-TYPE 10 434

Figure S4.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_1q22' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.032 (Fisher's exact test), Q value = 0.077

Table S5.  Gene #1: 'amp_1q22' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 1(1Q22) MUTATED 18 19 0 0
AMP PEAK 1(1Q22) WILD-TYPE 292 119 5 15

Figure S5.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_1q22' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000436 (Wilcoxon-test), Q value = 0.0027

Table S6.  Gene #1: 'amp_1q22' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 1(1Q22) MUTATED 35 1.2 (2.7)
AMP PEAK 1(1Q22) WILD-TYPE 360 0.4 (1.1)

Figure S6.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_1q22' versus 'GLEASON_SCORE_COMBINED'

P value = 9.55e-06 (Wilcoxon-test), Q value = 0.00012

Table S7.  Gene #1: 'amp_1q22' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 1(1Q22) MUTATED 38 8.3 (1.0)
AMP PEAK 1(1Q22) WILD-TYPE 444 7.5 (1.0)

Figure S7.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_1q22' versus 'GLEASON_SCORE_PRIMARY'

P value = 5.7e-06 (Wilcoxon-test), Q value = 9.1e-05

Table S8.  Gene #1: 'amp_1q22' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 1(1Q22) MUTATED 38 4.2 (0.7)
AMP PEAK 1(1Q22) WILD-TYPE 444 3.6 (0.7)

Figure S8.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_1q22' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0538 (Wilcoxon-test), Q value = 0.12

Table S9.  Gene #1: 'amp_1q22' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 1(1Q22) MUTATED 38 4.1 (0.7)
AMP PEAK 1(1Q22) WILD-TYPE 444 3.8 (0.7)

Figure S9.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_1q22' versus 'GLEASON_SCORE'

P value = 3.64e-07 (Wilcoxon-test), Q value = 7.9e-06

Table S10.  Gene #1: 'amp_1q22' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 1(1Q22) MUTATED 38 8.4 (0.9)
AMP PEAK 1(1Q22) WILD-TYPE 444 7.5 (1.0)

Figure S10.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_1q22' versus 'PSA_RESULT_PREOP'

P value = 0.0321 (Wilcoxon-test), Q value = 0.077

Table S11.  Gene #1: 'amp_1q22' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 1(1Q22) MUTATED 38 15.7 (15.1)
AMP PEAK 1(1Q22) WILD-TYPE 441 10.4 (11.2)

Figure S11.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_1q22' versus 'PSA_VALUE'

P value = 0.111 (Wilcoxon-test), Q value = 0.21

Table S12.  Gene #1: 'amp_1q22' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 1(1Q22) MUTATED 32 1.5 (3.5)
AMP PEAK 1(1Q22) WILD-TYPE 394 1.0 (4.2)

Figure S12.  Get High-res Image Gene #1: 'amp_1q22' versus Clinical Feature #13: 'PSA_VALUE'

'amp_3q21.3' versus 'Time to Death'

P value = 0.0647 (logrank test), Q value = 0.14

Table S13.  Gene #2: 'amp_3q21.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 481 8 0.7 - 165.2 (26.7)
AMP PEAK 2(3Q21.3) MUTATED 72 3 0.8 - 114.0 (27.8)
AMP PEAK 2(3Q21.3) WILD-TYPE 409 5 0.7 - 165.2 (26.3)

Figure S13.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #1: 'Time to Death'

'amp_3q21.3' versus 'YEARS_TO_BIRTH'

P value = 0.00296 (Wilcoxon-test), Q value = 0.011

Table S14.  Gene #2: 'amp_3q21.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 2(3Q21.3) MUTATED 69 63.1 (6.9)
AMP PEAK 2(3Q21.3) WILD-TYPE 402 60.5 (6.7)

Figure S14.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_3q21.3' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S15.  Gene #2: 'amp_3q21.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 2(3Q21.3) MUTATED 12 55 5
AMP PEAK 2(3Q21.3) WILD-TYPE 176 226 5

Figure S15.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_3q21.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.00312 (Fisher's exact test), Q value = 0.012

Table S16.  Gene #2: 'amp_3q21.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 2(3Q21.3) MUTATED 47 22
AMP PEAK 2(3Q21.3) WILD-TYPE 291 53

Figure S16.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_3q21.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.142 (Fisher's exact test), Q value = 0.25

Table S17.  Gene #2: 'amp_3q21.3' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 2(3Q21.3) MUTATED 4 68
AMP PEAK 2(3Q21.3) WILD-TYPE 10 400

Figure S17.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_3q21.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00025 (Fisher's exact test), Q value = 0.0017

Table S18.  Gene #2: 'amp_3q21.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 2(3Q21.3) MUTATED 31 31 2 5
AMP PEAK 2(3Q21.3) WILD-TYPE 279 107 3 10

Figure S18.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_3q21.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000214 (Wilcoxon-test), Q value = 0.0015

Table S19.  Gene #2: 'amp_3q21.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 2(3Q21.3) MUTATED 64 1.0 (1.9)
AMP PEAK 2(3Q21.3) WILD-TYPE 331 0.3 (1.2)

Figure S19.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_3q21.3' versus 'GLEASON_SCORE_COMBINED'

P value = 1.73e-08 (Wilcoxon-test), Q value = 6e-07

Table S20.  Gene #2: 'amp_3q21.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 2(3Q21.3) MUTATED 72 8.2 (1.0)
AMP PEAK 2(3Q21.3) WILD-TYPE 410 7.4 (1.0)

Figure S20.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_3q21.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 1.11e-07 (Wilcoxon-test), Q value = 2.9e-06

Table S21.  Gene #2: 'amp_3q21.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 2(3Q21.3) MUTATED 72 4.1 (0.6)
AMP PEAK 2(3Q21.3) WILD-TYPE 410 3.6 (0.7)

Figure S21.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_3q21.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00143 (Wilcoxon-test), Q value = 0.0066

Table S22.  Gene #2: 'amp_3q21.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 2(3Q21.3) MUTATED 72 4.1 (0.7)
AMP PEAK 2(3Q21.3) WILD-TYPE 410 3.8 (0.7)

Figure S22.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_3q21.3' versus 'GLEASON_SCORE'

P value = 2.01e-11 (Wilcoxon-test), Q value = 2.3e-09

Table S23.  Gene #2: 'amp_3q21.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 2(3Q21.3) MUTATED 72 8.3 (0.9)
AMP PEAK 2(3Q21.3) WILD-TYPE 410 7.5 (1.0)

Figure S23.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_3q21.3' versus 'PSA_RESULT_PREOP'

P value = 1.24e-05 (Wilcoxon-test), Q value = 0.00014

Table S24.  Gene #2: 'amp_3q21.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 2(3Q21.3) MUTATED 72 17.1 (18.3)
AMP PEAK 2(3Q21.3) WILD-TYPE 407 9.7 (9.6)

Figure S24.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_3q21.3' versus 'PSA_VALUE'

P value = 0.109 (Wilcoxon-test), Q value = 0.2

Table S25.  Gene #2: 'amp_3q21.3' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 2(3Q21.3) MUTATED 61 2.0 (6.7)
AMP PEAK 2(3Q21.3) WILD-TYPE 365 0.9 (3.5)

Figure S25.  Get High-res Image Gene #2: 'amp_3q21.3' versus Clinical Feature #13: 'PSA_VALUE'

'amp_3q26.2' versus 'Time to Death'

P value = 0.0688 (logrank test), Q value = 0.14

Table S26.  Gene #3: 'amp_3q26.2' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 481 8 0.7 - 165.2 (26.7)
AMP PEAK 3(3Q26.2) MUTATED 83 3 0.8 - 114.0 (26.0)
AMP PEAK 3(3Q26.2) WILD-TYPE 398 5 0.7 - 165.2 (27.1)

Figure S26.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #1: 'Time to Death'

'amp_3q26.2' versus 'YEARS_TO_BIRTH'

P value = 0.0252 (Wilcoxon-test), Q value = 0.064

Table S27.  Gene #3: 'amp_3q26.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 3(3Q26.2) MUTATED 80 62.5 (6.8)
AMP PEAK 3(3Q26.2) WILD-TYPE 391 60.6 (6.8)

Figure S27.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_3q26.2' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S28.  Gene #3: 'amp_3q26.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 3(3Q26.2) MUTATED 16 61 6
AMP PEAK 3(3Q26.2) WILD-TYPE 172 220 4

Figure S28.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_3q26.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.00105 (Fisher's exact test), Q value = 0.0051

Table S29.  Gene #3: 'amp_3q26.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 3(3Q26.2) MUTATED 54 25
AMP PEAK 3(3Q26.2) WILD-TYPE 284 50

Figure S29.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_3q26.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00013 (Fisher's exact test), Q value = 0.001

Table S30.  Gene #3: 'amp_3q26.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 3(3Q26.2) MUTATED 36 38 2 4
AMP PEAK 3(3Q26.2) WILD-TYPE 274 100 3 11

Figure S30.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_3q26.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000111 (Wilcoxon-test), Q value = 9e-04

Table S31.  Gene #3: 'amp_3q26.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 3(3Q26.2) MUTATED 75 1.0 (1.9)
AMP PEAK 3(3Q26.2) WILD-TYPE 320 0.3 (1.2)

Figure S31.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_3q26.2' versus 'GLEASON_SCORE_COMBINED'

P value = 3.26e-08 (Wilcoxon-test), Q value = 9.3e-07

Table S32.  Gene #3: 'amp_3q26.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 3(3Q26.2) MUTATED 83 8.1 (1.0)
AMP PEAK 3(3Q26.2) WILD-TYPE 399 7.4 (1.0)

Figure S32.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_3q26.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 5.48e-08 (Wilcoxon-test), Q value = 1.5e-06

Table S33.  Gene #3: 'amp_3q26.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 3(3Q26.2) MUTATED 83 4.1 (0.7)
AMP PEAK 3(3Q26.2) WILD-TYPE 399 3.6 (0.7)

Figure S33.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_3q26.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00494 (Wilcoxon-test), Q value = 0.016

Table S34.  Gene #3: 'amp_3q26.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 3(3Q26.2) MUTATED 83 4.1 (0.7)
AMP PEAK 3(3Q26.2) WILD-TYPE 399 3.8 (0.7)

Figure S34.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_3q26.2' versus 'GLEASON_SCORE'

P value = 6.66e-10 (Wilcoxon-test), Q value = 4.7e-08

Table S35.  Gene #3: 'amp_3q26.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 3(3Q26.2) MUTATED 83 8.2 (1.0)
AMP PEAK 3(3Q26.2) WILD-TYPE 399 7.5 (1.0)

Figure S35.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_3q26.2' versus 'PSA_RESULT_PREOP'

P value = 0.000121 (Wilcoxon-test), Q value = 0.00096

Table S36.  Gene #3: 'amp_3q26.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 3(3Q26.2) MUTATED 83 16.3 (17.6)
AMP PEAK 3(3Q26.2) WILD-TYPE 396 9.6 (9.6)

Figure S36.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_3q26.2' versus 'PSA_VALUE'

P value = 0.0407 (Wilcoxon-test), Q value = 0.093

Table S37.  Gene #3: 'amp_3q26.2' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 3(3Q26.2) MUTATED 73 2.7 (8.1)
AMP PEAK 3(3Q26.2) WILD-TYPE 353 0.7 (2.6)

Figure S37.  Get High-res Image Gene #3: 'amp_3q26.2' versus Clinical Feature #13: 'PSA_VALUE'

'amp_4p16.3' versus 'YEARS_TO_BIRTH'

P value = 0.0393 (Wilcoxon-test), Q value = 0.091

Table S38.  Gene #4: 'amp_4p16.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 4(4P16.3) MUTATED 18 63.7 (6.6)
AMP PEAK 4(4P16.3) WILD-TYPE 453 60.8 (6.8)

Figure S38.  Get High-res Image Gene #4: 'amp_4p16.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_4p16.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.00083 (Fisher's exact test), Q value = 0.0041

Table S39.  Gene #4: 'amp_4p16.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 4(4P16.3) MUTATED 1 16 2
AMP PEAK 4(4P16.3) WILD-TYPE 187 265 8

Figure S39.  Get High-res Image Gene #4: 'amp_4p16.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_4p16.3' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0274 (Wilcoxon-test), Q value = 0.068

Table S40.  Gene #4: 'amp_4p16.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 4(4P16.3) MUTATED 19 8.1 (1.0)
AMP PEAK 4(4P16.3) WILD-TYPE 463 7.5 (1.0)

Figure S40.  Get High-res Image Gene #4: 'amp_4p16.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_4p16.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00708 (Wilcoxon-test), Q value = 0.023

Table S41.  Gene #4: 'amp_4p16.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 4(4P16.3) MUTATED 19 4.1 (0.7)
AMP PEAK 4(4P16.3) WILD-TYPE 463 3.7 (0.7)

Figure S41.  Get High-res Image Gene #4: 'amp_4p16.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_4p16.3' versus 'GLEASON_SCORE'

P value = 0.0063 (Wilcoxon-test), Q value = 0.02

Table S42.  Gene #4: 'amp_4p16.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 4(4P16.3) MUTATED 19 8.2 (1.0)
AMP PEAK 4(4P16.3) WILD-TYPE 463 7.6 (1.0)

Figure S42.  Get High-res Image Gene #4: 'amp_4p16.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_4p16.3' versus 'PSA_RESULT_PREOP'

P value = 0.0106 (Wilcoxon-test), Q value = 0.032

Table S43.  Gene #4: 'amp_4p16.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 4(4P16.3) MUTATED 19 13.2 (7.5)
AMP PEAK 4(4P16.3) WILD-TYPE 460 10.7 (11.8)

Figure S43.  Get High-res Image Gene #4: 'amp_4p16.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_4q13.3' versus 'YEARS_TO_BIRTH'

P value = 0.0163 (Wilcoxon-test), Q value = 0.045

Table S44.  Gene #5: 'amp_4q13.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 5(4Q13.3) MUTATED 20 64.6 (5.5)
AMP PEAK 5(4Q13.3) WILD-TYPE 451 60.7 (6.8)

Figure S44.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_4q13.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.00149 (Fisher's exact test), Q value = 0.0067

Table S45.  Gene #5: 'amp_4q13.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 5(4Q13.3) MUTATED 2 18 2
AMP PEAK 5(4Q13.3) WILD-TYPE 186 263 8

Figure S45.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_4q13.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.000462 (Fisher's exact test), Q value = 0.0027

Table S46.  Gene #5: 'amp_4q13.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 5(4Q13.3) MUTATED 11 11
AMP PEAK 5(4Q13.3) WILD-TYPE 327 64

Figure S46.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_4q13.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00398 (Fisher's exact test), Q value = 0.014

Table S47.  Gene #5: 'amp_4q13.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 5(4Q13.3) MUTATED 7 14 0 1
AMP PEAK 5(4Q13.3) WILD-TYPE 303 124 5 14

Figure S47.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_4q13.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 4.53e-05 (Wilcoxon-test), Q value = 0.00041

Table S48.  Gene #5: 'amp_4q13.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 5(4Q13.3) MUTATED 21 1.2 (1.7)
AMP PEAK 5(4Q13.3) WILD-TYPE 374 0.4 (1.3)

Figure S48.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_4q13.3' versus 'GLEASON_SCORE_COMBINED'

P value = 5.42e-05 (Wilcoxon-test), Q value = 0.00048

Table S49.  Gene #5: 'amp_4q13.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 5(4Q13.3) MUTATED 22 8.5 (1.0)
AMP PEAK 5(4Q13.3) WILD-TYPE 460 7.5 (1.0)

Figure S49.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_4q13.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 2.65e-05 (Wilcoxon-test), Q value = 0.00027

Table S50.  Gene #5: 'amp_4q13.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 5(4Q13.3) MUTATED 22 4.3 (0.6)
AMP PEAK 5(4Q13.3) WILD-TYPE 460 3.7 (0.7)

Figure S50.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_4q13.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0537 (Wilcoxon-test), Q value = 0.12

Table S51.  Gene #5: 'amp_4q13.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 5(4Q13.3) MUTATED 22 4.1 (0.6)
AMP PEAK 5(4Q13.3) WILD-TYPE 460 3.9 (0.7)

Figure S51.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_4q13.3' versus 'GLEASON_SCORE'

P value = 0.000173 (Wilcoxon-test), Q value = 0.0013

Table S52.  Gene #5: 'amp_4q13.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 5(4Q13.3) MUTATED 22 8.4 (1.0)
AMP PEAK 5(4Q13.3) WILD-TYPE 460 7.5 (1.0)

Figure S52.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_4q13.3' versus 'PSA_RESULT_PREOP'

P value = 0.00483 (Wilcoxon-test), Q value = 0.016

Table S53.  Gene #5: 'amp_4q13.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 5(4Q13.3) MUTATED 22 15.6 (13.9)
AMP PEAK 5(4Q13.3) WILD-TYPE 457 10.6 (11.5)

Figure S53.  Get High-res Image Gene #5: 'amp_4q13.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_5q35.3' versus 'YEARS_TO_BIRTH'

P value = 1.71e-07 (Wilcoxon-test), Q value = 3.9e-06

Table S54.  Gene #6: 'amp_5q35.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 6(5Q35.3) MUTATED 28 67.1 (4.0)
AMP PEAK 6(5Q35.3) WILD-TYPE 443 60.5 (6.8)

Figure S54.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_5q35.3' versus 'PATHOLOGY_T_STAGE'

P value = 2e-04 (Fisher's exact test), Q value = 0.0014

Table S55.  Gene #6: 'amp_5q35.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 6(5Q35.3) MUTATED 2 24 2
AMP PEAK 6(5Q35.3) WILD-TYPE 186 257 8

Figure S55.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_5q35.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.000632 (Fisher's exact test), Q value = 0.0034

Table S56.  Gene #6: 'amp_5q35.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 6(5Q35.3) MUTATED 14 12
AMP PEAK 6(5Q35.3) WILD-TYPE 324 63

Figure S56.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_5q35.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0572 (Fisher's exact test), Q value = 0.12

Table S57.  Gene #6: 'amp_5q35.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 6(5Q35.3) MUTATED 13 13 1 1
AMP PEAK 6(5Q35.3) WILD-TYPE 297 125 4 14

Figure S57.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_5q35.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 5.53e-05 (Wilcoxon-test), Q value = 0.00049

Table S58.  Gene #6: 'amp_5q35.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 6(5Q35.3) MUTATED 25 1.8 (3.5)
AMP PEAK 6(5Q35.3) WILD-TYPE 370 0.3 (1.0)

Figure S58.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_5q35.3' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00283 (Wilcoxon-test), Q value = 0.011

Table S59.  Gene #6: 'amp_5q35.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 6(5Q35.3) MUTATED 28 8.1 (1.0)
AMP PEAK 6(5Q35.3) WILD-TYPE 454 7.5 (1.0)

Figure S59.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_5q35.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000514 (Wilcoxon-test), Q value = 0.0029

Table S60.  Gene #6: 'amp_5q35.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 6(5Q35.3) MUTATED 28 4.1 (0.6)
AMP PEAK 6(5Q35.3) WILD-TYPE 454 3.7 (0.7)

Figure S60.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_5q35.3' versus 'GLEASON_SCORE'

P value = 2.1e-05 (Wilcoxon-test), Q value = 0.00022

Table S61.  Gene #6: 'amp_5q35.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 6(5Q35.3) MUTATED 28 8.4 (0.8)
AMP PEAK 6(5Q35.3) WILD-TYPE 454 7.5 (1.0)

Figure S61.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_5q35.3' versus 'PSA_RESULT_PREOP'

P value = 0.034 (Wilcoxon-test), Q value = 0.081

Table S62.  Gene #6: 'amp_5q35.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 6(5Q35.3) MUTATED 28 13.6 (11.6)
AMP PEAK 6(5Q35.3) WILD-TYPE 451 10.6 (11.6)

Figure S62.  Get High-res Image Gene #6: 'amp_5q35.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_7p14.3' versus 'YEARS_TO_BIRTH'

P value = 0.0078 (Wilcoxon-test), Q value = 0.025

Table S63.  Gene #7: 'amp_7p14.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 7(7P14.3) MUTATED 98 62.4 (6.8)
AMP PEAK 7(7P14.3) WILD-TYPE 373 60.5 (6.8)

Figure S63.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_7p14.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.0223 (Fisher's exact test), Q value = 0.058

Table S64.  Gene #7: 'amp_7p14.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 7(7P14.3) MUTATED 28 71 2
AMP PEAK 7(7P14.3) WILD-TYPE 160 210 8

Figure S64.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_7p14.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00126 (Fisher's exact test), Q value = 0.0059

Table S65.  Gene #7: 'amp_7p14.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 7(7P14.3) MUTATED 49 44 1 4
AMP PEAK 7(7P14.3) WILD-TYPE 261 94 4 11

Figure S65.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_7p14.3' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00173 (Wilcoxon-test), Q value = 0.0074

Table S66.  Gene #7: 'amp_7p14.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 7(7P14.3) MUTATED 101 7.9 (1.1)
AMP PEAK 7(7P14.3) WILD-TYPE 381 7.5 (1.0)

Figure S66.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_7p14.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00439 (Wilcoxon-test), Q value = 0.015

Table S67.  Gene #7: 'amp_7p14.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 7(7P14.3) MUTATED 101 3.9 (0.7)
AMP PEAK 7(7P14.3) WILD-TYPE 381 3.6 (0.7)

Figure S67.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_7p14.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0358 (Wilcoxon-test), Q value = 0.085

Table S68.  Gene #7: 'amp_7p14.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 7(7P14.3) MUTATED 101 4.0 (0.7)
AMP PEAK 7(7P14.3) WILD-TYPE 381 3.8 (0.7)

Figure S68.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_7p14.3' versus 'GLEASON_SCORE'

P value = 0.000244 (Wilcoxon-test), Q value = 0.0016

Table S69.  Gene #7: 'amp_7p14.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 7(7P14.3) MUTATED 101 7.9 (1.1)
AMP PEAK 7(7P14.3) WILD-TYPE 381 7.5 (1.0)

Figure S69.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_7p14.3' versus 'PSA_RESULT_PREOP'

P value = 0.0781 (Wilcoxon-test), Q value = 0.16

Table S70.  Gene #7: 'amp_7p14.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 7(7P14.3) MUTATED 101 12.3 (11.8)
AMP PEAK 7(7P14.3) WILD-TYPE 378 10.4 (11.6)

Figure S70.  Get High-res Image Gene #7: 'amp_7p14.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_7q22.1' versus 'YEARS_TO_BIRTH'

P value = 0.00591 (Wilcoxon-test), Q value = 0.019

Table S71.  Gene #8: 'amp_7q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 8(7Q22.1) MUTATED 96 62.4 (6.8)
AMP PEAK 8(7Q22.1) WILD-TYPE 375 60.5 (6.7)

Figure S71.  Get High-res Image Gene #8: 'amp_7q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_7q22.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.0707 (Fisher's exact test), Q value = 0.15

Table S72.  Gene #8: 'amp_7q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 8(7Q22.1) MUTATED 29 67 2
AMP PEAK 8(7Q22.1) WILD-TYPE 159 214 8

Figure S72.  Get High-res Image Gene #8: 'amp_7q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_7q22.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00255 (Fisher's exact test), Q value = 0.0099

Table S73.  Gene #8: 'amp_7q22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 8(7Q22.1) MUTATED 49 43 1 3
AMP PEAK 8(7Q22.1) WILD-TYPE 261 95 4 12

Figure S73.  Get High-res Image Gene #8: 'amp_7q22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_7q22.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00188 (Wilcoxon-test), Q value = 0.0078

Table S74.  Gene #8: 'amp_7q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 8(7Q22.1) MUTATED 98 7.9 (1.1)
AMP PEAK 8(7Q22.1) WILD-TYPE 384 7.5 (1.0)

Figure S74.  Get High-res Image Gene #8: 'amp_7q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_7q22.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00276 (Wilcoxon-test), Q value = 0.011

Table S75.  Gene #8: 'amp_7q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 8(7Q22.1) MUTATED 98 3.9 (0.7)
AMP PEAK 8(7Q22.1) WILD-TYPE 384 3.6 (0.7)

Figure S75.  Get High-res Image Gene #8: 'amp_7q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_7q22.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0555 (Wilcoxon-test), Q value = 0.12

Table S76.  Gene #8: 'amp_7q22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 8(7Q22.1) MUTATED 98 4.0 (0.7)
AMP PEAK 8(7Q22.1) WILD-TYPE 384 3.8 (0.7)

Figure S76.  Get High-res Image Gene #8: 'amp_7q22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_7q22.1' versus 'GLEASON_SCORE'

P value = 0.000226 (Wilcoxon-test), Q value = 0.0015

Table S77.  Gene #8: 'amp_7q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 8(7Q22.1) MUTATED 98 7.9 (1.1)
AMP PEAK 8(7Q22.1) WILD-TYPE 384 7.5 (1.0)

Figure S77.  Get High-res Image Gene #8: 'amp_7q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_8p11.23' versus 'YEARS_TO_BIRTH'

P value = 0.000452 (Wilcoxon-test), Q value = 0.0027

Table S78.  Gene #9: 'amp_8p11.23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 9(8P11.23) MUTATED 63 63.6 (6.5)
AMP PEAK 9(8P11.23) WILD-TYPE 408 60.5 (6.8)

Figure S78.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_8p11.23' versus 'PATHOLOGY_T_STAGE'

P value = 0.00439 (Fisher's exact test), Q value = 0.015

Table S79.  Gene #9: 'amp_8p11.23' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 9(8P11.23) MUTATED 15 48 3
AMP PEAK 9(8P11.23) WILD-TYPE 173 233 7

Figure S79.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_8p11.23' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0135 (Fisher's exact test), Q value = 0.039

Table S80.  Gene #9: 'amp_8p11.23' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 9(8P11.23) MUTATED 31 28 1 3
AMP PEAK 9(8P11.23) WILD-TYPE 279 110 4 12

Figure S80.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_8p11.23' versus 'GLEASON_SCORE_COMBINED'

P value = 6.33e-06 (Wilcoxon-test), Q value = 9.9e-05

Table S81.  Gene #9: 'amp_8p11.23' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 9(8P11.23) MUTATED 66 8.1 (1.0)
AMP PEAK 9(8P11.23) WILD-TYPE 416 7.5 (1.0)

Figure S81.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_8p11.23' versus 'GLEASON_SCORE_PRIMARY'

P value = 4.92e-07 (Wilcoxon-test), Q value = 1e-05

Table S82.  Gene #9: 'amp_8p11.23' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 9(8P11.23) MUTATED 66 4.1 (0.7)
AMP PEAK 9(8P11.23) WILD-TYPE 416 3.6 (0.7)

Figure S82.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_8p11.23' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.119 (Wilcoxon-test), Q value = 0.22

Table S83.  Gene #9: 'amp_8p11.23' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 9(8P11.23) MUTATED 66 4.0 (0.7)
AMP PEAK 9(8P11.23) WILD-TYPE 416 3.8 (0.7)

Figure S83.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_8p11.23' versus 'GLEASON_SCORE'

P value = 1.43e-06 (Wilcoxon-test), Q value = 2.6e-05

Table S84.  Gene #9: 'amp_8p11.23' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 9(8P11.23) MUTATED 66 8.2 (1.0)
AMP PEAK 9(8P11.23) WILD-TYPE 416 7.5 (1.0)

Figure S84.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_8p11.23' versus 'PSA_RESULT_PREOP'

P value = 0.00432 (Wilcoxon-test), Q value = 0.015

Table S85.  Gene #9: 'amp_8p11.23' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 9(8P11.23) MUTATED 66 14.6 (14.4)
AMP PEAK 9(8P11.23) WILD-TYPE 413 10.2 (11.0)

Figure S85.  Get High-res Image Gene #9: 'amp_8p11.23' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_8q22.1' versus 'YEARS_TO_BIRTH'

P value = 0.0747 (Wilcoxon-test), Q value = 0.15

Table S86.  Gene #10: 'amp_8q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 10(8Q22.1) MUTATED 149 61.7 (6.3)
AMP PEAK 10(8Q22.1) WILD-TYPE 322 60.5 (7.0)

Figure S86.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_8q22.1' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S87.  Gene #10: 'amp_8q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 10(8Q22.1) MUTATED 33 113 6
AMP PEAK 10(8Q22.1) WILD-TYPE 155 168 4

Figure S87.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_8q22.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.00315 (Fisher's exact test), Q value = 0.012

Table S88.  Gene #10: 'amp_8q22.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 10(8Q22.1) MUTATED 105 37
AMP PEAK 10(8Q22.1) WILD-TYPE 233 38

Figure S88.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_8q22.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S89.  Gene #10: 'amp_8q22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 10(8Q22.1) MUTATED 75 65 1 7
AMP PEAK 10(8Q22.1) WILD-TYPE 235 73 4 8

Figure S89.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_8q22.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00114 (Wilcoxon-test), Q value = 0.0055

Table S90.  Gene #10: 'amp_8q22.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 10(8Q22.1) MUTATED 135 0.7 (1.6)
AMP PEAK 10(8Q22.1) WILD-TYPE 260 0.3 (1.2)

Figure S90.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_8q22.1' versus 'GLEASON_SCORE_COMBINED'

P value = 1.69e-11 (Wilcoxon-test), Q value = 2.2e-09

Table S91.  Gene #10: 'amp_8q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 10(8Q22.1) MUTATED 152 8.0 (1.0)
AMP PEAK 10(8Q22.1) WILD-TYPE 330 7.3 (1.0)

Figure S91.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_8q22.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 4.49e-12 (Wilcoxon-test), Q value = 1e-09

Table S92.  Gene #10: 'amp_8q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 10(8Q22.1) MUTATED 152 4.0 (0.7)
AMP PEAK 10(8Q22.1) WILD-TYPE 330 3.5 (0.6)

Figure S92.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_8q22.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00293 (Wilcoxon-test), Q value = 0.011

Table S93.  Gene #10: 'amp_8q22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 10(8Q22.1) MUTATED 152 4.0 (0.7)
AMP PEAK 10(8Q22.1) WILD-TYPE 330 3.8 (0.6)

Figure S93.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_8q22.1' versus 'GLEASON_SCORE'

P value = 5.87e-13 (Wilcoxon-test), Q value = 4.7e-10

Table S94.  Gene #10: 'amp_8q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 10(8Q22.1) MUTATED 152 8.1 (1.0)
AMP PEAK 10(8Q22.1) WILD-TYPE 330 7.4 (0.9)

Figure S94.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_8q22.1' versus 'PSA_RESULT_PREOP'

P value = 0.000526 (Wilcoxon-test), Q value = 0.0029

Table S95.  Gene #10: 'amp_8q22.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 10(8Q22.1) MUTATED 152 13.5 (15.5)
AMP PEAK 10(8Q22.1) WILD-TYPE 327 9.5 (9.1)

Figure S95.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_8q22.1' versus 'PSA_VALUE'

P value = 0.0542 (Wilcoxon-test), Q value = 0.12

Table S96.  Gene #10: 'amp_8q22.1' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 10(8Q22.1) MUTATED 132 1.5 (4.9)
AMP PEAK 10(8Q22.1) WILD-TYPE 294 0.9 (3.8)

Figure S96.  Get High-res Image Gene #10: 'amp_8q22.1' versus Clinical Feature #13: 'PSA_VALUE'

'amp_8q24.21' versus 'YEARS_TO_BIRTH'

P value = 0.0512 (Wilcoxon-test), Q value = 0.11

Table S97.  Gene #11: 'amp_8q24.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 11(8Q24.21) MUTATED 144 61.8 (6.3)
AMP PEAK 11(8Q24.21) WILD-TYPE 327 60.5 (7.0)

Figure S97.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_8q24.21' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S98.  Gene #11: 'amp_8q24.21' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 11(8Q24.21) MUTATED 33 109 6
AMP PEAK 11(8Q24.21) WILD-TYPE 155 172 4

Figure S98.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_8q24.21' versus 'PATHOLOGY_N_STAGE'

P value = 0.000675 (Fisher's exact test), Q value = 0.0036

Table S99.  Gene #11: 'amp_8q24.21' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 11(8Q24.21) MUTATED 100 38
AMP PEAK 11(8Q24.21) WILD-TYPE 238 37

Figure S99.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_8q24.21' versus 'COMPLETENESS_OF_RESECTION'

P value = 8e-05 (Fisher's exact test), Q value = 0.00067

Table S100.  Gene #11: 'amp_8q24.21' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 11(8Q24.21) MUTATED 75 61 1 7
AMP PEAK 11(8Q24.21) WILD-TYPE 235 77 4 8

Figure S100.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_8q24.21' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000179 (Wilcoxon-test), Q value = 0.0013

Table S101.  Gene #11: 'amp_8q24.21' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 11(8Q24.21) MUTATED 131 0.7 (1.4)
AMP PEAK 11(8Q24.21) WILD-TYPE 264 0.3 (1.3)

Figure S101.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_8q24.21' versus 'GLEASON_SCORE_COMBINED'

P value = 1.06e-11 (Wilcoxon-test), Q value = 1.6e-09

Table S102.  Gene #11: 'amp_8q24.21' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 11(8Q24.21) MUTATED 148 8.0 (1.0)
AMP PEAK 11(8Q24.21) WILD-TYPE 334 7.3 (0.9)

Figure S102.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_8q24.21' versus 'GLEASON_SCORE_PRIMARY'

P value = 1.03e-12 (Wilcoxon-test), Q value = 4.7e-10

Table S103.  Gene #11: 'amp_8q24.21' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 11(8Q24.21) MUTATED 148 4.0 (0.7)
AMP PEAK 11(8Q24.21) WILD-TYPE 334 3.5 (0.6)

Figure S103.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_8q24.21' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00248 (Wilcoxon-test), Q value = 0.0096

Table S104.  Gene #11: 'amp_8q24.21' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 11(8Q24.21) MUTATED 148 4.0 (0.7)
AMP PEAK 11(8Q24.21) WILD-TYPE 334 3.8 (0.6)

Figure S104.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_8q24.21' versus 'GLEASON_SCORE'

P value = 1.68e-12 (Wilcoxon-test), Q value = 5.1e-10

Table S105.  Gene #11: 'amp_8q24.21' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 11(8Q24.21) MUTATED 148 8.1 (1.0)
AMP PEAK 11(8Q24.21) WILD-TYPE 334 7.4 (0.9)

Figure S105.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_8q24.21' versus 'PSA_RESULT_PREOP'

P value = 0.000354 (Wilcoxon-test), Q value = 0.0023

Table S106.  Gene #11: 'amp_8q24.21' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 11(8Q24.21) MUTATED 148 13.4 (14.3)
AMP PEAK 11(8Q24.21) WILD-TYPE 331 9.6 (10.1)

Figure S106.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_8q24.21' versus 'PSA_VALUE'

P value = 0.0374 (Wilcoxon-test), Q value = 0.088

Table S107.  Gene #11: 'amp_8q24.21' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 11(8Q24.21) MUTATED 126 1.6 (5.0)
AMP PEAK 11(8Q24.21) WILD-TYPE 300 0.9 (3.7)

Figure S107.  Get High-res Image Gene #11: 'amp_8q24.21' versus Clinical Feature #13: 'PSA_VALUE'

'amp_9q33.3' versus 'YEARS_TO_BIRTH'

P value = 0.0179 (Wilcoxon-test), Q value = 0.049

Table S108.  Gene #12: 'amp_9q33.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 12(9Q33.3) MUTATED 56 63.0 (6.5)
AMP PEAK 12(9Q33.3) WILD-TYPE 415 60.6 (6.8)

Figure S108.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_9q33.3' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S109.  Gene #12: 'amp_9q33.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 12(9Q33.3) MUTATED 5 50 3
AMP PEAK 12(9Q33.3) WILD-TYPE 183 231 7

Figure S109.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_9q33.3' versus 'PATHOLOGY_N_STAGE'

P value = 1.78e-08 (Fisher's exact test), Q value = 6e-07

Table S110.  Gene #12: 'amp_9q33.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 12(9Q33.3) MUTATED 29 27
AMP PEAK 12(9Q33.3) WILD-TYPE 309 48

Figure S110.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_9q33.3' versus 'HISTOLOGICAL_TYPE'

P value = 0.0751 (Fisher's exact test), Q value = 0.15

Table S111.  Gene #12: 'amp_9q33.3' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 12(9Q33.3) MUTATED 4 54
AMP PEAK 12(9Q33.3) WILD-TYPE 10 414

Figure S111.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_9q33.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00179 (Fisher's exact test), Q value = 0.0076

Table S112.  Gene #12: 'amp_9q33.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 12(9Q33.3) MUTATED 26 29 1 1
AMP PEAK 12(9Q33.3) WILD-TYPE 284 109 4 14

Figure S112.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_9q33.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 3.7e-10 (Wilcoxon-test), Q value = 3.4e-08

Table S113.  Gene #12: 'amp_9q33.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 12(9Q33.3) MUTATED 56 1.4 (2.5)
AMP PEAK 12(9Q33.3) WILD-TYPE 339 0.3 (1.0)

Figure S113.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_9q33.3' versus 'GLEASON_SCORE_COMBINED'

P value = 1.91e-10 (Wilcoxon-test), Q value = 1.9e-08

Table S114.  Gene #12: 'amp_9q33.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 12(9Q33.3) MUTATED 58 8.4 (1.0)
AMP PEAK 12(9Q33.3) WILD-TYPE 424 7.4 (1.0)

Figure S114.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_9q33.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 4.98e-10 (Wilcoxon-test), Q value = 3.8e-08

Table S115.  Gene #12: 'amp_9q33.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 12(9Q33.3) MUTATED 58 4.2 (0.6)
AMP PEAK 12(9Q33.3) WILD-TYPE 424 3.6 (0.7)

Figure S115.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_9q33.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.000403 (Wilcoxon-test), Q value = 0.0025

Table S116.  Gene #12: 'amp_9q33.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 12(9Q33.3) MUTATED 58 4.2 (0.7)
AMP PEAK 12(9Q33.3) WILD-TYPE 424 3.8 (0.7)

Figure S116.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_9q33.3' versus 'GLEASON_SCORE'

P value = 9.99e-12 (Wilcoxon-test), Q value = 1.6e-09

Table S117.  Gene #12: 'amp_9q33.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 12(9Q33.3) MUTATED 58 8.4 (0.8)
AMP PEAK 12(9Q33.3) WILD-TYPE 424 7.5 (1.0)

Figure S117.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_9q33.3' versus 'PSA_RESULT_PREOP'

P value = 0.000782 (Wilcoxon-test), Q value = 0.004

Table S118.  Gene #12: 'amp_9q33.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 12(9Q33.3) MUTATED 58 15.4 (15.1)
AMP PEAK 12(9Q33.3) WILD-TYPE 421 10.2 (11.0)

Figure S118.  Get High-res Image Gene #12: 'amp_9q33.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_11q13.2' versus 'YEARS_TO_BIRTH'

P value = 0.000571 (Wilcoxon-test), Q value = 0.0031

Table S119.  Gene #13: 'amp_11q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 13(11Q13.2) MUTATED 44 64.0 (5.9)
AMP PEAK 13(11Q13.2) WILD-TYPE 427 60.6 (6.8)

Figure S119.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_11q13.2' versus 'PATHOLOGY_T_STAGE'

P value = 4e-05 (Fisher's exact test), Q value = 0.00038

Table S120.  Gene #13: 'amp_11q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 13(11Q13.2) MUTATED 5 38 3
AMP PEAK 13(11Q13.2) WILD-TYPE 183 243 7

Figure S120.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_11q13.2' versus 'PATHOLOGY_N_STAGE'

P value = 1.55e-05 (Fisher's exact test), Q value = 0.00017

Table S121.  Gene #13: 'amp_11q13.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 13(11Q13.2) MUTATED 23 19
AMP PEAK 13(11Q13.2) WILD-TYPE 315 56

Figure S121.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_11q13.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00389 (Fisher's exact test), Q value = 0.014

Table S122.  Gene #13: 'amp_11q13.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 13(11Q13.2) MUTATED 20 24 0 2
AMP PEAK 13(11Q13.2) WILD-TYPE 290 114 5 13

Figure S122.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_11q13.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 8.3e-07 (Wilcoxon-test), Q value = 1.6e-05

Table S123.  Gene #13: 'amp_11q13.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 13(11Q13.2) MUTATED 40 1.4 (2.8)
AMP PEAK 13(11Q13.2) WILD-TYPE 355 0.3 (1.0)

Figure S123.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_11q13.2' versus 'GLEASON_SCORE_COMBINED'

P value = 4.44e-08 (Wilcoxon-test), Q value = 1.2e-06

Table S124.  Gene #13: 'amp_11q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 13(11Q13.2) MUTATED 46 8.3 (1.0)
AMP PEAK 13(11Q13.2) WILD-TYPE 436 7.5 (1.0)

Figure S124.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_11q13.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 6.53e-09 (Wilcoxon-test), Q value = 3e-07

Table S125.  Gene #13: 'amp_11q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 13(11Q13.2) MUTATED 46 4.3 (0.7)
AMP PEAK 13(11Q13.2) WILD-TYPE 436 3.6 (0.7)

Figure S125.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_11q13.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0406 (Wilcoxon-test), Q value = 0.093

Table S126.  Gene #13: 'amp_11q13.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 13(11Q13.2) MUTATED 46 4.1 (0.7)
AMP PEAK 13(11Q13.2) WILD-TYPE 436 3.8 (0.7)

Figure S126.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_11q13.2' versus 'GLEASON_SCORE'

P value = 2.2e-08 (Wilcoxon-test), Q value = 7.2e-07

Table S127.  Gene #13: 'amp_11q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 13(11Q13.2) MUTATED 46 8.4 (0.9)
AMP PEAK 13(11Q13.2) WILD-TYPE 436 7.5 (1.0)

Figure S127.  Get High-res Image Gene #13: 'amp_11q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_12q23.1' versus 'YEARS_TO_BIRTH'

P value = 0.0988 (Wilcoxon-test), Q value = 0.19

Table S128.  Gene #14: 'amp_12q23.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 14(12Q23.1) MUTATED 35 62.8 (6.5)
AMP PEAK 14(12Q23.1) WILD-TYPE 436 60.7 (6.8)

Figure S128.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_12q23.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.00061 (Fisher's exact test), Q value = 0.0033

Table S129.  Gene #14: 'amp_12q23.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 14(12Q23.1) MUTATED 4 31 1
AMP PEAK 14(12Q23.1) WILD-TYPE 184 250 9

Figure S129.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_12q23.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.000175 (Fisher's exact test), Q value = 0.0013

Table S130.  Gene #14: 'amp_12q23.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 14(12Q23.1) MUTATED 16 14
AMP PEAK 14(12Q23.1) WILD-TYPE 322 61

Figure S130.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_12q23.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00014 (Fisher's exact test), Q value = 0.0011

Table S131.  Gene #14: 'amp_12q23.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 14(12Q23.1) MUTATED 13 22 1 0
AMP PEAK 14(12Q23.1) WILD-TYPE 297 116 4 15

Figure S131.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_12q23.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 2.37e-05 (Wilcoxon-test), Q value = 0.00025

Table S132.  Gene #14: 'amp_12q23.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 14(12Q23.1) MUTATED 29 1.3 (2.4)
AMP PEAK 14(12Q23.1) WILD-TYPE 366 0.4 (1.2)

Figure S132.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_12q23.1' versus 'GLEASON_SCORE_COMBINED'

P value = 1.32e-05 (Wilcoxon-test), Q value = 0.00015

Table S133.  Gene #14: 'amp_12q23.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 14(12Q23.1) MUTATED 36 8.3 (1.0)
AMP PEAK 14(12Q23.1) WILD-TYPE 446 7.5 (1.0)

Figure S133.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_12q23.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 1.16e-07 (Wilcoxon-test), Q value = 2.9e-06

Table S134.  Gene #14: 'amp_12q23.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 14(12Q23.1) MUTATED 36 4.3 (0.7)
AMP PEAK 14(12Q23.1) WILD-TYPE 446 3.6 (0.7)

Figure S134.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_12q23.1' versus 'GLEASON_SCORE'

P value = 5.05e-07 (Wilcoxon-test), Q value = 1e-05

Table S135.  Gene #14: 'amp_12q23.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 14(12Q23.1) MUTATED 36 8.4 (1.0)
AMP PEAK 14(12Q23.1) WILD-TYPE 446 7.5 (1.0)

Figure S135.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_12q23.1' versus 'PSA_RESULT_PREOP'

P value = 8.68e-05 (Wilcoxon-test), Q value = 0.00072

Table S136.  Gene #14: 'amp_12q23.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 14(12Q23.1) MUTATED 36 15.5 (10.9)
AMP PEAK 14(12Q23.1) WILD-TYPE 443 10.4 (11.6)

Figure S136.  Get High-res Image Gene #14: 'amp_12q23.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_13q12.11' versus 'YEARS_TO_BIRTH'

P value = 0.000321 (Wilcoxon-test), Q value = 0.0021

Table S137.  Gene #15: 'amp_13q12.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 15(13Q12.11) MUTATED 24 65.5 (4.2)
AMP PEAK 15(13Q12.11) WILD-TYPE 447 60.6 (6.8)

Figure S137.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_13q12.11' versus 'PATHOLOGY_T_STAGE'

P value = 0.00421 (Fisher's exact test), Q value = 0.015

Table S138.  Gene #15: 'amp_13q12.11' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 15(13Q12.11) MUTATED 5 17 3
AMP PEAK 15(13Q12.11) WILD-TYPE 183 264 7

Figure S138.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_13q12.11' versus 'PATHOLOGY_N_STAGE'

P value = 0.0936 (Fisher's exact test), Q value = 0.18

Table S139.  Gene #15: 'amp_13q12.11' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 15(13Q12.11) MUTATED 15 7
AMP PEAK 15(13Q12.11) WILD-TYPE 323 68

Figure S139.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_13q12.11' versus 'HISTOLOGICAL_TYPE'

P value = 0.0307 (Fisher's exact test), Q value = 0.075

Table S140.  Gene #15: 'amp_13q12.11' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 15(13Q12.11) MUTATED 3 22
AMP PEAK 15(13Q12.11) WILD-TYPE 11 446

Figure S140.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_13q12.11' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0796 (Wilcoxon-test), Q value = 0.16

Table S141.  Gene #15: 'amp_13q12.11' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 15(13Q12.11) MUTATED 21 0.7 (1.4)
AMP PEAK 15(13Q12.11) WILD-TYPE 374 0.4 (1.4)

Figure S141.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_13q12.11' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0236 (Wilcoxon-test), Q value = 0.061

Table S142.  Gene #15: 'amp_13q12.11' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 15(13Q12.11) MUTATED 25 8.0 (1.2)
AMP PEAK 15(13Q12.11) WILD-TYPE 457 7.5 (1.0)

Figure S142.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_13q12.11' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00321 (Wilcoxon-test), Q value = 0.012

Table S143.  Gene #15: 'amp_13q12.11' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 15(13Q12.11) MUTATED 25 4.1 (0.8)
AMP PEAK 15(13Q12.11) WILD-TYPE 457 3.7 (0.7)

Figure S143.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_13q12.11' versus 'GLEASON_SCORE'

P value = 0.0079 (Wilcoxon-test), Q value = 0.025

Table S144.  Gene #15: 'amp_13q12.11' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 15(13Q12.11) MUTATED 25 8.1 (1.1)
AMP PEAK 15(13Q12.11) WILD-TYPE 457 7.6 (1.0)

Figure S144.  Get High-res Image Gene #15: 'amp_13q12.11' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_14q21.1' versus 'YEARS_TO_BIRTH'

P value = 0.0223 (Wilcoxon-test), Q value = 0.058

Table S145.  Gene #16: 'amp_14q21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 16(14Q21.1) MUTATED 25 63.6 (5.7)
AMP PEAK 16(14Q21.1) WILD-TYPE 446 60.7 (6.8)

Figure S145.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_14q21.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.132 (Fisher's exact test), Q value = 0.23

Table S146.  Gene #16: 'amp_14q21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 16(14Q21.1) MUTATED 6 21 0
AMP PEAK 16(14Q21.1) WILD-TYPE 182 260 10

Figure S146.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_14q21.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0477 (Fisher's exact test), Q value = 0.11

Table S147.  Gene #16: 'amp_14q21.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 16(14Q21.1) MUTATED 15 8
AMP PEAK 16(14Q21.1) WILD-TYPE 323 67

Figure S147.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_14q21.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0224 (Wilcoxon-test), Q value = 0.058

Table S148.  Gene #16: 'amp_14q21.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 16(14Q21.1) MUTATED 23 1.2 (2.2)
AMP PEAK 16(14Q21.1) WILD-TYPE 372 0.4 (1.3)

Figure S148.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_14q21.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00742 (Wilcoxon-test), Q value = 0.024

Table S149.  Gene #16: 'amp_14q21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 16(14Q21.1) MUTATED 27 8.1 (1.1)
AMP PEAK 16(14Q21.1) WILD-TYPE 455 7.5 (1.0)

Figure S149.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_14q21.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0278 (Wilcoxon-test), Q value = 0.069

Table S150.  Gene #16: 'amp_14q21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 16(14Q21.1) MUTATED 27 4.0 (0.8)
AMP PEAK 16(14Q21.1) WILD-TYPE 455 3.7 (0.7)

Figure S150.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_14q21.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.101 (Wilcoxon-test), Q value = 0.19

Table S151.  Gene #16: 'amp_14q21.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 16(14Q21.1) MUTATED 27 4.1 (0.7)
AMP PEAK 16(14Q21.1) WILD-TYPE 455 3.9 (0.7)

Figure S151.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_14q21.1' versus 'GLEASON_SCORE'

P value = 0.000491 (Wilcoxon-test), Q value = 0.0028

Table S152.  Gene #16: 'amp_14q21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 16(14Q21.1) MUTATED 27 8.2 (0.9)
AMP PEAK 16(14Q21.1) WILD-TYPE 455 7.5 (1.0)

Figure S152.  Get High-res Image Gene #16: 'amp_14q21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_15q11.2' versus 'Time to Death'

P value = 0.0829 (logrank test), Q value = 0.16

Table S153.  Gene #17: 'amp_15q11.2' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 481 8 0.7 - 165.2 (26.7)
AMP PEAK 17(15Q11.2) MUTATED 15 1 4.3 - 69.3 (32.0)
AMP PEAK 17(15Q11.2) WILD-TYPE 466 7 0.7 - 165.2 (26.4)

Figure S153.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #1: 'Time to Death'

'amp_15q11.2' versus 'YEARS_TO_BIRTH'

P value = 0.0774 (Wilcoxon-test), Q value = 0.16

Table S154.  Gene #17: 'amp_15q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 17(15Q11.2) MUTATED 14 63.8 (7.7)
AMP PEAK 17(15Q11.2) WILD-TYPE 457 60.8 (6.8)

Figure S154.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_15q11.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.118 (Fisher's exact test), Q value = 0.22

Table S155.  Gene #17: 'amp_15q11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 17(15Q11.2) MUTATED 3 11 1
AMP PEAK 17(15Q11.2) WILD-TYPE 185 270 9

Figure S155.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_15q11.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.000129 (Fisher's exact test), Q value = 0.001

Table S156.  Gene #17: 'amp_15q11.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 17(15Q11.2) MUTATED 5 9
AMP PEAK 17(15Q11.2) WILD-TYPE 333 66

Figure S156.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_15q11.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0285 (Fisher's exact test), Q value = 0.07

Table S157.  Gene #17: 'amp_15q11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 17(15Q11.2) MUTATED 5 10 0 0
AMP PEAK 17(15Q11.2) WILD-TYPE 305 128 5 15

Figure S157.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_15q11.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 3.85e-06 (Wilcoxon-test), Q value = 6.5e-05

Table S158.  Gene #17: 'amp_15q11.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 17(15Q11.2) MUTATED 14 1.4 (1.3)
AMP PEAK 17(15Q11.2) WILD-TYPE 381 0.4 (1.4)

Figure S158.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_15q11.2' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00207 (Wilcoxon-test), Q value = 0.0082

Table S159.  Gene #17: 'amp_15q11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 17(15Q11.2) MUTATED 15 8.4 (1.1)
AMP PEAK 17(15Q11.2) WILD-TYPE 467 7.5 (1.0)

Figure S159.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_15q11.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00104 (Wilcoxon-test), Q value = 0.0051

Table S160.  Gene #17: 'amp_15q11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 17(15Q11.2) MUTATED 15 4.3 (0.6)
AMP PEAK 17(15Q11.2) WILD-TYPE 467 3.7 (0.7)

Figure S160.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_15q11.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.134 (Wilcoxon-test), Q value = 0.24

Table S161.  Gene #17: 'amp_15q11.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 17(15Q11.2) MUTATED 15 4.1 (0.7)
AMP PEAK 17(15Q11.2) WILD-TYPE 467 3.9 (0.7)

Figure S161.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_15q11.2' versus 'GLEASON_SCORE'

P value = 0.00235 (Wilcoxon-test), Q value = 0.0092

Table S162.  Gene #17: 'amp_15q11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 17(15Q11.2) MUTATED 15 8.4 (1.0)
AMP PEAK 17(15Q11.2) WILD-TYPE 467 7.6 (1.0)

Figure S162.  Get High-res Image Gene #17: 'amp_15q11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_16q11.2' versus 'YEARS_TO_BIRTH'

P value = 0.0309 (Wilcoxon-test), Q value = 0.075

Table S163.  Gene #18: 'amp_16q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 18(16Q11.2) MUTATED 27 63.5 (6.3)
AMP PEAK 18(16Q11.2) WILD-TYPE 444 60.7 (6.8)

Figure S163.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_16q11.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.00044 (Fisher's exact test), Q value = 0.0027

Table S164.  Gene #18: 'amp_16q11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 18(16Q11.2) MUTATED 2 26 1
AMP PEAK 18(16Q11.2) WILD-TYPE 186 255 9

Figure S164.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_16q11.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.122 (Fisher's exact test), Q value = 0.22

Table S165.  Gene #18: 'amp_16q11.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 18(16Q11.2) MUTATED 19 8
AMP PEAK 18(16Q11.2) WILD-TYPE 319 67

Figure S165.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_16q11.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0552 (Fisher's exact test), Q value = 0.12

Table S166.  Gene #18: 'amp_16q11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 18(16Q11.2) MUTATED 13 15 0 1
AMP PEAK 18(16Q11.2) WILD-TYPE 297 123 5 14

Figure S166.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_16q11.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.115 (Wilcoxon-test), Q value = 0.21

Table S167.  Gene #18: 'amp_16q11.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 18(16Q11.2) MUTATED 26 0.7 (1.6)
AMP PEAK 18(16Q11.2) WILD-TYPE 369 0.4 (1.4)

Figure S167.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_16q11.2' versus 'GLEASON_SCORE_COMBINED'

P value = 1.85e-05 (Wilcoxon-test), Q value = 2e-04

Table S168.  Gene #18: 'amp_16q11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 18(16Q11.2) MUTATED 29 8.4 (1.0)
AMP PEAK 18(16Q11.2) WILD-TYPE 453 7.5 (1.0)

Figure S168.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_16q11.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000995 (Wilcoxon-test), Q value = 0.0049

Table S169.  Gene #18: 'amp_16q11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 18(16Q11.2) MUTATED 29 4.1 (0.8)
AMP PEAK 18(16Q11.2) WILD-TYPE 453 3.7 (0.7)

Figure S169.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_16q11.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0027 (Wilcoxon-test), Q value = 0.01

Table S170.  Gene #18: 'amp_16q11.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 18(16Q11.2) MUTATED 29 4.2 (0.7)
AMP PEAK 18(16Q11.2) WILD-TYPE 453 3.8 (0.7)

Figure S170.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_16q11.2' versus 'GLEASON_SCORE'

P value = 2.14e-06 (Wilcoxon-test), Q value = 3.7e-05

Table S171.  Gene #18: 'amp_16q11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 18(16Q11.2) MUTATED 29 8.5 (0.9)
AMP PEAK 18(16Q11.2) WILD-TYPE 453 7.5 (1.0)

Figure S171.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_16q11.2' versus 'PSA_RESULT_PREOP'

P value = 0.00442 (Wilcoxon-test), Q value = 0.015

Table S172.  Gene #18: 'amp_16q11.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 18(16Q11.2) MUTATED 29 16.6 (17.1)
AMP PEAK 18(16Q11.2) WILD-TYPE 450 10.4 (11.1)

Figure S172.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_16q11.2' versus 'PSA_VALUE'

P value = 0.0148 (Wilcoxon-test), Q value = 0.042

Table S173.  Gene #18: 'amp_16q11.2' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 18(16Q11.2) MUTATED 23 1.4 (2.6)
AMP PEAK 18(16Q11.2) WILD-TYPE 403 1.1 (4.2)

Figure S173.  Get High-res Image Gene #18: 'amp_16q11.2' versus Clinical Feature #13: 'PSA_VALUE'

'amp_17q23.2' versus 'YEARS_TO_BIRTH'

P value = 0.122 (Wilcoxon-test), Q value = 0.22

Table S174.  Gene #19: 'amp_17q23.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 19(17Q23.2) MUTATED 23 63.0 (6.6)
AMP PEAK 19(17Q23.2) WILD-TYPE 448 60.8 (6.8)

Figure S174.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_17q23.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.00072 (Fisher's exact test), Q value = 0.0037

Table S175.  Gene #19: 'amp_17q23.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 19(17Q23.2) MUTATED 2 20 2
AMP PEAK 19(17Q23.2) WILD-TYPE 186 261 8

Figure S175.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_17q23.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0212 (Fisher's exact test), Q value = 0.057

Table S176.  Gene #19: 'amp_17q23.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 19(17Q23.2) MUTATED 14 9
AMP PEAK 19(17Q23.2) WILD-TYPE 324 66

Figure S176.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_17q23.2' versus 'HISTOLOGICAL_TYPE'

P value = 0.0275 (Fisher's exact test), Q value = 0.068

Table S177.  Gene #19: 'amp_17q23.2' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 19(17Q23.2) MUTATED 3 21
AMP PEAK 19(17Q23.2) WILD-TYPE 11 447

Figure S177.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_17q23.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0104 (Wilcoxon-test), Q value = 0.032

Table S178.  Gene #19: 'amp_17q23.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 19(17Q23.2) MUTATED 23 0.7 (0.9)
AMP PEAK 19(17Q23.2) WILD-TYPE 372 0.4 (1.4)

Figure S178.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_17q23.2' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00201 (Wilcoxon-test), Q value = 0.0081

Table S179.  Gene #19: 'amp_17q23.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 19(17Q23.2) MUTATED 24 8.2 (1.2)
AMP PEAK 19(17Q23.2) WILD-TYPE 458 7.5 (1.0)

Figure S179.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_17q23.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00178 (Wilcoxon-test), Q value = 0.0076

Table S180.  Gene #19: 'amp_17q23.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 19(17Q23.2) MUTATED 24 4.1 (0.7)
AMP PEAK 19(17Q23.2) WILD-TYPE 458 3.7 (0.7)

Figure S180.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_17q23.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0642 (Wilcoxon-test), Q value = 0.14

Table S181.  Gene #19: 'amp_17q23.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 19(17Q23.2) MUTATED 24 4.1 (0.7)
AMP PEAK 19(17Q23.2) WILD-TYPE 458 3.9 (0.7)

Figure S181.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_17q23.2' versus 'GLEASON_SCORE'

P value = 0.000166 (Wilcoxon-test), Q value = 0.0012

Table S182.  Gene #19: 'amp_17q23.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 19(17Q23.2) MUTATED 24 8.4 (1.0)
AMP PEAK 19(17Q23.2) WILD-TYPE 458 7.5 (1.0)

Figure S182.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_17q23.2' versus 'PSA_VALUE'

P value = 0.113 (Wilcoxon-test), Q value = 0.21

Table S183.  Gene #19: 'amp_17q23.2' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 19(17Q23.2) MUTATED 21 0.9 (2.7)
AMP PEAK 19(17Q23.2) WILD-TYPE 405 1.1 (4.2)

Figure S183.  Get High-res Image Gene #19: 'amp_17q23.2' versus Clinical Feature #13: 'PSA_VALUE'

'amp_19q13.43' versus 'YEARS_TO_BIRTH'

P value = 0.0175 (Wilcoxon-test), Q value = 0.048

Table S184.  Gene #20: 'amp_19q13.43' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 20(19Q13.43) MUTATED 16 64.8 (6.9)
AMP PEAK 20(19Q13.43) WILD-TYPE 455 60.8 (6.8)

Figure S184.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_19q13.43' versus 'PATHOLOGY_T_STAGE'

P value = 4e-04 (Fisher's exact test), Q value = 0.0025

Table S185.  Gene #20: 'amp_19q13.43' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 20(19Q13.43) MUTATED 0 16 1
AMP PEAK 20(19Q13.43) WILD-TYPE 188 265 9

Figure S185.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_19q13.43' versus 'PATHOLOGY_N_STAGE'

P value = 0.0206 (Fisher's exact test), Q value = 0.055

Table S186.  Gene #20: 'amp_19q13.43' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 20(19Q13.43) MUTATED 10 7
AMP PEAK 20(19Q13.43) WILD-TYPE 328 68

Figure S186.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_19q13.43' versus 'HISTOLOGICAL_TYPE'

P value = 0.0831 (Fisher's exact test), Q value = 0.16

Table S187.  Gene #20: 'amp_19q13.43' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 20(19Q13.43) MUTATED 2 15
AMP PEAK 20(19Q13.43) WILD-TYPE 12 453

Figure S187.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_19q13.43' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0108 (Wilcoxon-test), Q value = 0.033

Table S188.  Gene #20: 'amp_19q13.43' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 20(19Q13.43) MUTATED 17 1.1 (2.0)
AMP PEAK 20(19Q13.43) WILD-TYPE 378 0.4 (1.3)

Figure S188.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_19q13.43' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000859 (Wilcoxon-test), Q value = 0.0043

Table S189.  Gene #20: 'amp_19q13.43' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 20(19Q13.43) MUTATED 17 8.4 (1.0)
AMP PEAK 20(19Q13.43) WILD-TYPE 465 7.5 (1.0)

Figure S189.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_19q13.43' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000468 (Wilcoxon-test), Q value = 0.0027

Table S190.  Gene #20: 'amp_19q13.43' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 20(19Q13.43) MUTATED 17 4.3 (0.7)
AMP PEAK 20(19Q13.43) WILD-TYPE 465 3.7 (0.7)

Figure S190.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_19q13.43' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.124 (Wilcoxon-test), Q value = 0.22

Table S191.  Gene #20: 'amp_19q13.43' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
AMP PEAK 20(19Q13.43) MUTATED 17 4.1 (0.7)
AMP PEAK 20(19Q13.43) WILD-TYPE 465 3.9 (0.7)

Figure S191.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'amp_19q13.43' versus 'GLEASON_SCORE'

P value = 2.77e-05 (Wilcoxon-test), Q value = 0.00028

Table S192.  Gene #20: 'amp_19q13.43' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 20(19Q13.43) MUTATED 17 8.6 (0.9)
AMP PEAK 20(19Q13.43) WILD-TYPE 465 7.5 (1.0)

Figure S192.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_19q13.43' versus 'PSA_RESULT_PREOP'

P value = 0.0342 (Wilcoxon-test), Q value = 0.082

Table S193.  Gene #20: 'amp_19q13.43' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 20(19Q13.43) MUTATED 17 14.0 (9.8)
AMP PEAK 20(19Q13.43) WILD-TYPE 462 10.7 (11.7)

Figure S193.  Get High-res Image Gene #20: 'amp_19q13.43' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_20q13.2' versus 'YEARS_TO_BIRTH'

P value = 0.0019 (Wilcoxon-test), Q value = 0.0078

Table S194.  Gene #21: 'amp_20q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 21(20Q13.2) MUTATED 39 63.9 (4.5)
AMP PEAK 21(20Q13.2) WILD-TYPE 432 60.6 (6.9)

Figure S194.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_20q13.2' versus 'PATHOLOGY_T_STAGE'

P value = 5e-05 (Fisher's exact test), Q value = 0.00045

Table S195.  Gene #21: 'amp_20q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 21(20Q13.2) MUTATED 4 35 3
AMP PEAK 21(20Q13.2) WILD-TYPE 184 246 7

Figure S195.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_20q13.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0153 (Fisher's exact test), Q value = 0.044

Table S196.  Gene #21: 'amp_20q13.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 21(20Q13.2) MUTATED 26 13
AMP PEAK 21(20Q13.2) WILD-TYPE 312 62

Figure S196.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_20q13.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00973 (Fisher's exact test), Q value = 0.03

Table S197.  Gene #21: 'amp_20q13.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 21(20Q13.2) MUTATED 18 21 0 2
AMP PEAK 21(20Q13.2) WILD-TYPE 292 117 5 13

Figure S197.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_20q13.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00736 (Wilcoxon-test), Q value = 0.023

Table S198.  Gene #21: 'amp_20q13.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 21(20Q13.2) MUTATED 37 0.8 (1.5)
AMP PEAK 21(20Q13.2) WILD-TYPE 358 0.4 (1.4)

Figure S198.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_20q13.2' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000216 (Wilcoxon-test), Q value = 0.0015

Table S199.  Gene #21: 'amp_20q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 21(20Q13.2) MUTATED 42 8.1 (1.1)
AMP PEAK 21(20Q13.2) WILD-TYPE 440 7.5 (1.0)

Figure S199.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_20q13.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 1.36e-05 (Wilcoxon-test), Q value = 0.00015

Table S200.  Gene #21: 'amp_20q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 21(20Q13.2) MUTATED 42 4.1 (0.7)
AMP PEAK 21(20Q13.2) WILD-TYPE 440 3.6 (0.7)

Figure S200.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_20q13.2' versus 'GLEASON_SCORE'

P value = 6.14e-07 (Wilcoxon-test), Q value = 1.2e-05

Table S201.  Gene #21: 'amp_20q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 21(20Q13.2) MUTATED 42 8.4 (1.0)
AMP PEAK 21(20Q13.2) WILD-TYPE 440 7.5 (1.0)

Figure S201.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_20q13.2' versus 'PSA_RESULT_PREOP'

P value = 0.0789 (Wilcoxon-test), Q value = 0.16

Table S202.  Gene #21: 'amp_20q13.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 21(20Q13.2) MUTATED 42 13.8 (16.3)
AMP PEAK 21(20Q13.2) WILD-TYPE 437 10.5 (11.1)

Figure S202.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_20q13.2' versus 'PSA_VALUE'

P value = 0.0805 (Wilcoxon-test), Q value = 0.16

Table S203.  Gene #21: 'amp_20q13.2' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 21(20Q13.2) MUTATED 41 1.1 (2.5)
AMP PEAK 21(20Q13.2) WILD-TYPE 385 1.1 (4.3)

Figure S203.  Get High-res Image Gene #21: 'amp_20q13.2' versus Clinical Feature #13: 'PSA_VALUE'

'amp_xp22.11' versus 'YEARS_TO_BIRTH'

P value = 0.016 (Wilcoxon-test), Q value = 0.045

Table S204.  Gene #22: 'amp_xp22.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 22(XP22.11) MUTATED 23 64.2 (6.0)
AMP PEAK 22(XP22.11) WILD-TYPE 448 60.7 (6.8)

Figure S204.  Get High-res Image Gene #22: 'amp_xp22.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_xp22.11' versus 'PATHOLOGY_T_STAGE'

P value = 0.00268 (Fisher's exact test), Q value = 0.01

Table S205.  Gene #22: 'amp_xp22.11' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 22(XP22.11) MUTATED 4 17 3
AMP PEAK 22(XP22.11) WILD-TYPE 184 264 7

Figure S205.  Get High-res Image Gene #22: 'amp_xp22.11' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_xp22.11' versus 'HISTOLOGICAL_TYPE'

P value = 0.0275 (Fisher's exact test), Q value = 0.068

Table S206.  Gene #22: 'amp_xp22.11' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 22(XP22.11) MUTATED 3 21
AMP PEAK 22(XP22.11) WILD-TYPE 11 447

Figure S206.  Get High-res Image Gene #22: 'amp_xp22.11' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_xp22.11' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0245 (Fisher's exact test), Q value = 0.062

Table S207.  Gene #22: 'amp_xp22.11' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 22(XP22.11) MUTATED 9 11 1 1
AMP PEAK 22(XP22.11) WILD-TYPE 301 127 4 14

Figure S207.  Get High-res Image Gene #22: 'amp_xp22.11' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_xp22.11' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00154 (Wilcoxon-test), Q value = 0.0069

Table S208.  Gene #22: 'amp_xp22.11' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 22(XP22.11) MUTATED 24 8.2 (0.9)
AMP PEAK 22(XP22.11) WILD-TYPE 458 7.5 (1.0)

Figure S208.  Get High-res Image Gene #22: 'amp_xp22.11' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_xp22.11' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000215 (Wilcoxon-test), Q value = 0.0015

Table S209.  Gene #22: 'amp_xp22.11' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 22(XP22.11) MUTATED 24 4.2 (0.7)
AMP PEAK 22(XP22.11) WILD-TYPE 458 3.7 (0.7)

Figure S209.  Get High-res Image Gene #22: 'amp_xp22.11' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_xp22.11' versus 'GLEASON_SCORE'

P value = 0.00141 (Wilcoxon-test), Q value = 0.0065

Table S210.  Gene #22: 'amp_xp22.11' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 22(XP22.11) MUTATED 24 8.2 (0.9)
AMP PEAK 22(XP22.11) WILD-TYPE 458 7.6 (1.0)

Figure S210.  Get High-res Image Gene #22: 'amp_xp22.11' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_xp22.11' versus 'YEARS_TO_BIRTH'

P value = 0.0943 (Wilcoxon-test), Q value = 0.18

Table S211.  Gene #23: 'amp_xp22.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 23(XP22.11) MUTATED 22 63.2 (7.3)
AMP PEAK 23(XP22.11) WILD-TYPE 449 60.8 (6.8)

Figure S211.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_xp22.11' versus 'PATHOLOGY_T_STAGE'

P value = 0.00197 (Fisher's exact test), Q value = 0.008

Table S212.  Gene #23: 'amp_xp22.11' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 23(XP22.11) MUTATED 4 16 3
AMP PEAK 23(XP22.11) WILD-TYPE 184 265 7

Figure S212.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_xp22.11' versus 'HISTOLOGICAL_TYPE'

P value = 0.0245 (Fisher's exact test), Q value = 0.062

Table S213.  Gene #23: 'amp_xp22.11' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 23(XP22.11) MUTATED 3 20
AMP PEAK 23(XP22.11) WILD-TYPE 11 448

Figure S213.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_xp22.11' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0242 (Fisher's exact test), Q value = 0.062

Table S214.  Gene #23: 'amp_xp22.11' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 23(XP22.11) MUTATED 9 11 1 1
AMP PEAK 23(XP22.11) WILD-TYPE 301 127 4 14

Figure S214.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_xp22.11' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.128 (Wilcoxon-test), Q value = 0.23

Table S215.  Gene #23: 'amp_xp22.11' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 23(XP22.11) MUTATED 23 0.7 (1.5)
AMP PEAK 23(XP22.11) WILD-TYPE 372 0.4 (1.4)

Figure S215.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_xp22.11' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000818 (Wilcoxon-test), Q value = 0.0041

Table S216.  Gene #23: 'amp_xp22.11' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 23(XP22.11) MUTATED 23 8.2 (0.9)
AMP PEAK 23(XP22.11) WILD-TYPE 459 7.5 (1.0)

Figure S216.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_xp22.11' versus 'GLEASON_SCORE_PRIMARY'

P value = 6.16e-05 (Wilcoxon-test), Q value = 0.00053

Table S217.  Gene #23: 'amp_xp22.11' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 23(XP22.11) MUTATED 23 4.3 (0.6)
AMP PEAK 23(XP22.11) WILD-TYPE 459 3.7 (0.7)

Figure S217.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_xp22.11' versus 'GLEASON_SCORE'

P value = 0.00169 (Wilcoxon-test), Q value = 0.0073

Table S218.  Gene #23: 'amp_xp22.11' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 23(XP22.11) MUTATED 23 8.2 (1.0)
AMP PEAK 23(XP22.11) WILD-TYPE 459 7.6 (1.0)

Figure S218.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_xp22.11' versus 'PSA_RESULT_PREOP'

P value = 0.073 (Wilcoxon-test), Q value = 0.15

Table S219.  Gene #23: 'amp_xp22.11' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 23(XP22.11) MUTATED 23 13.8 (14.6)
AMP PEAK 23(XP22.11) WILD-TYPE 456 10.6 (11.5)

Figure S219.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_xp22.11' versus 'PSA_VALUE'

P value = 0.0781 (Wilcoxon-test), Q value = 0.16

Table S220.  Gene #23: 'amp_xp22.11' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 23(XP22.11) MUTATED 19 0.6 (1.0)
AMP PEAK 23(XP22.11) WILD-TYPE 407 1.1 (4.2)

Figure S220.  Get High-res Image Gene #23: 'amp_xp22.11' versus Clinical Feature #13: 'PSA_VALUE'

'amp_xp21.1' versus 'YEARS_TO_BIRTH'

P value = 0.00191 (Wilcoxon-test), Q value = 0.0078

Table S221.  Gene #24: 'amp_xp21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 24(XP21.1) MUTATED 20 65.3 (5.0)
AMP PEAK 24(XP21.1) WILD-TYPE 451 60.7 (6.8)

Figure S221.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_xp21.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.00528 (Fisher's exact test), Q value = 0.017

Table S222.  Gene #24: 'amp_xp21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 24(XP21.1) MUTATED 3 17 2
AMP PEAK 24(XP21.1) WILD-TYPE 185 264 8

Figure S222.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_xp21.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0936 (Fisher's exact test), Q value = 0.18

Table S223.  Gene #24: 'amp_xp21.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 24(XP21.1) MUTATED 15 7
AMP PEAK 24(XP21.1) WILD-TYPE 323 68

Figure S223.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_xp21.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.0217 (Fisher's exact test), Q value = 0.057

Table S224.  Gene #24: 'amp_xp21.1' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
AMP PEAK 24(XP21.1) MUTATED 3 19
AMP PEAK 24(XP21.1) WILD-TYPE 11 449

Figure S224.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'amp_xp21.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0241 (Fisher's exact test), Q value = 0.062

Table S225.  Gene #24: 'amp_xp21.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 24(XP21.1) MUTATED 9 11 1 1
AMP PEAK 24(XP21.1) WILD-TYPE 301 127 4 14

Figure S225.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_xp21.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0974 (Wilcoxon-test), Q value = 0.19

Table S226.  Gene #24: 'amp_xp21.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 24(XP21.1) MUTATED 22 0.8 (1.5)
AMP PEAK 24(XP21.1) WILD-TYPE 373 0.4 (1.4)

Figure S226.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_xp21.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00152 (Wilcoxon-test), Q value = 0.0069

Table S227.  Gene #24: 'amp_xp21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 24(XP21.1) MUTATED 22 8.2 (0.9)
AMP PEAK 24(XP21.1) WILD-TYPE 460 7.5 (1.0)

Figure S227.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_xp21.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000124 (Wilcoxon-test), Q value = 0.00097

Table S228.  Gene #24: 'amp_xp21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 24(XP21.1) MUTATED 22 4.3 (0.7)
AMP PEAK 24(XP21.1) WILD-TYPE 460 3.7 (0.7)

Figure S228.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_xp21.1' versus 'GLEASON_SCORE'

P value = 0.000344 (Wilcoxon-test), Q value = 0.0022

Table S229.  Gene #24: 'amp_xp21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 24(XP21.1) MUTATED 22 8.3 (0.8)
AMP PEAK 24(XP21.1) WILD-TYPE 460 7.6 (1.0)

Figure S229.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_xp21.1' versus 'PSA_RESULT_PREOP'

P value = 0.0713 (Wilcoxon-test), Q value = 0.15

Table S230.  Gene #24: 'amp_xp21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 24(XP21.1) MUTATED 22 14.0 (14.7)
AMP PEAK 24(XP21.1) WILD-TYPE 457 10.6 (11.5)

Figure S230.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_xp21.1' versus 'PSA_VALUE'

P value = 0.0902 (Wilcoxon-test), Q value = 0.17

Table S231.  Gene #24: 'amp_xp21.1' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
AMP PEAK 24(XP21.1) MUTATED 19 0.6 (1.0)
AMP PEAK 24(XP21.1) WILD-TYPE 407 1.1 (4.2)

Figure S231.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #13: 'PSA_VALUE'

'amp_xp21.1' versus 'RACE'

P value = 0.00762 (Fisher's exact test), Q value = 0.024

Table S232.  Gene #24: 'amp_xp21.1' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
AMP PEAK 24(XP21.1) MUTATED 1 1 2
AMP PEAK 24(XP21.1) WILD-TYPE 1 6 144

Figure S232.  Get High-res Image Gene #24: 'amp_xp21.1' versus Clinical Feature #14: 'RACE'

'amp_xq21.1' versus 'YEARS_TO_BIRTH'

P value = 0.0763 (Wilcoxon-test), Q value = 0.15

Table S233.  Gene #25: 'amp_xq21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 25(XQ21.1) MUTATED 15 64.1 (5.7)
AMP PEAK 25(XQ21.1) WILD-TYPE 456 60.8 (6.8)

Figure S233.  Get High-res Image Gene #25: 'amp_xq21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_xq21.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.0377 (Fisher's exact test), Q value = 0.088

Table S234.  Gene #25: 'amp_xq21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 25(XQ21.1) MUTATED 4 9 2
AMP PEAK 25(XQ21.1) WILD-TYPE 184 272 8

Figure S234.  Get High-res Image Gene #25: 'amp_xq21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_xq21.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0972 (Wilcoxon-test), Q value = 0.19

Table S235.  Gene #25: 'amp_xq21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 25(XQ21.1) MUTATED 15 7.9 (0.9)
AMP PEAK 25(XQ21.1) WILD-TYPE 467 7.5 (1.0)

Figure S235.  Get High-res Image Gene #25: 'amp_xq21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_xq21.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0661 (Wilcoxon-test), Q value = 0.14

Table S236.  Gene #25: 'amp_xq21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 25(XQ21.1) MUTATED 15 4.0 (0.7)
AMP PEAK 25(XQ21.1) WILD-TYPE 467 3.7 (0.7)

Figure S236.  Get High-res Image Gene #25: 'amp_xq21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_xq21.1' versus 'GLEASON_SCORE'

P value = 0.00944 (Wilcoxon-test), Q value = 0.029

Table S237.  Gene #25: 'amp_xq21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 25(XQ21.1) MUTATED 15 8.3 (1.0)
AMP PEAK 25(XQ21.1) WILD-TYPE 467 7.6 (1.0)

Figure S237.  Get High-res Image Gene #25: 'amp_xq21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_xq21.1' versus 'PSA_RESULT_PREOP'

P value = 0.0376 (Wilcoxon-test), Q value = 0.088

Table S238.  Gene #25: 'amp_xq21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 25(XQ21.1) MUTATED 15 12.4 (7.7)
AMP PEAK 25(XQ21.1) WILD-TYPE 464 10.7 (11.8)

Figure S238.  Get High-res Image Gene #25: 'amp_xq21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_xq21.1' versus 'YEARS_TO_BIRTH'

P value = 0.0215 (Wilcoxon-test), Q value = 0.057

Table S239.  Gene #26: 'amp_xq21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 26(XQ21.1) MUTATED 13 65.2 (5.3)
AMP PEAK 26(XQ21.1) WILD-TYPE 458 60.8 (6.8)

Figure S239.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_xq21.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.0239 (Fisher's exact test), Q value = 0.062

Table S240.  Gene #26: 'amp_xq21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 26(XQ21.1) MUTATED 3 8 2
AMP PEAK 26(XQ21.1) WILD-TYPE 185 273 8

Figure S240.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_xq21.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0671 (Fisher's exact test), Q value = 0.14

Table S241.  Gene #26: 'amp_xq21.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
AMP PEAK 26(XQ21.1) MUTATED 8 5
AMP PEAK 26(XQ21.1) WILD-TYPE 330 70

Figure S241.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'amp_xq21.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0906 (Fisher's exact test), Q value = 0.18

Table S242.  Gene #26: 'amp_xq21.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
AMP PEAK 26(XQ21.1) MUTATED 7 4 1 1
AMP PEAK 26(XQ21.1) WILD-TYPE 303 134 4 14

Figure S242.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'amp_xq21.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0682 (Wilcoxon-test), Q value = 0.14

Table S243.  Gene #26: 'amp_xq21.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
AMP PEAK 26(XQ21.1) MUTATED 13 0.9 (1.8)
AMP PEAK 26(XQ21.1) WILD-TYPE 382 0.4 (1.4)

Figure S243.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'amp_xq21.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0375 (Wilcoxon-test), Q value = 0.088

Table S244.  Gene #26: 'amp_xq21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 26(XQ21.1) MUTATED 13 8.1 (0.9)
AMP PEAK 26(XQ21.1) WILD-TYPE 469 7.5 (1.0)

Figure S244.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_xq21.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0349 (Wilcoxon-test), Q value = 0.083

Table S245.  Gene #26: 'amp_xq21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 26(XQ21.1) MUTATED 13 4.1 (0.6)
AMP PEAK 26(XQ21.1) WILD-TYPE 469 3.7 (0.7)

Figure S245.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_xq21.1' versus 'GLEASON_SCORE'

P value = 0.00375 (Wilcoxon-test), Q value = 0.013

Table S246.  Gene #26: 'amp_xq21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 26(XQ21.1) MUTATED 13 8.4 (0.9)
AMP PEAK 26(XQ21.1) WILD-TYPE 469 7.6 (1.0)

Figure S246.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_xq21.1' versus 'PSA_RESULT_PREOP'

P value = 0.0117 (Wilcoxon-test), Q value = 0.035

Table S247.  Gene #26: 'amp_xq21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
AMP PEAK 26(XQ21.1) MUTATED 13 13.6 (7.8)
AMP PEAK 26(XQ21.1) WILD-TYPE 466 10.7 (11.7)

Figure S247.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'amp_xq21.1' versus 'RACE'

P value = 0.0268 (Fisher's exact test), Q value = 0.068

Table S248.  Gene #26: 'amp_xq21.1' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
AMP PEAK 26(XQ21.1) MUTATED 0 2 3
AMP PEAK 26(XQ21.1) WILD-TYPE 2 5 143

Figure S248.  Get High-res Image Gene #26: 'amp_xq21.1' versus Clinical Feature #14: 'RACE'

'amp_xq25' versus 'PATHOLOGY_T_STAGE'

P value = 0.0594 (Fisher's exact test), Q value = 0.13

Table S249.  Gene #27: 'amp_xq25' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 27(XQ25) MUTATED 5 10 2
AMP PEAK 27(XQ25) WILD-TYPE 183 271 8

Figure S249.  Get High-res Image Gene #27: 'amp_xq25' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_xq25' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0388 (Wilcoxon-test), Q value = 0.09

Table S250.  Gene #27: 'amp_xq25' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 27(XQ25) MUTATED 17 8.0 (0.9)
AMP PEAK 27(XQ25) WILD-TYPE 465 7.5 (1.0)

Figure S250.  Get High-res Image Gene #27: 'amp_xq25' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'amp_xq25' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.108 (Wilcoxon-test), Q value = 0.2

Table S251.  Gene #27: 'amp_xq25' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
AMP PEAK 27(XQ25) MUTATED 17 3.9 (0.7)
AMP PEAK 27(XQ25) WILD-TYPE 465 3.7 (0.7)

Figure S251.  Get High-res Image Gene #27: 'amp_xq25' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'amp_xq25' versus 'GLEASON_SCORE'

P value = 0.0232 (Wilcoxon-test), Q value = 0.06

Table S252.  Gene #27: 'amp_xq25' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 27(XQ25) MUTATED 17 8.1 (0.9)
AMP PEAK 27(XQ25) WILD-TYPE 465 7.6 (1.0)

Figure S252.  Get High-res Image Gene #27: 'amp_xq25' versus Clinical Feature #11: 'GLEASON_SCORE'

'amp_xq25' versus 'RACE'

P value = 0.0188 (Fisher's exact test), Q value = 0.051

Table S253.  Gene #27: 'amp_xq25' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
AMP PEAK 27(XQ25) MUTATED 1 1 4
AMP PEAK 27(XQ25) WILD-TYPE 1 6 142

Figure S253.  Get High-res Image Gene #27: 'amp_xq25' versus Clinical Feature #14: 'RACE'

'amp_xq27.1' versus 'YEARS_TO_BIRTH'

P value = 0.0185 (Wilcoxon-test), Q value = 0.051

Table S254.  Gene #28: 'amp_xq27.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
AMP PEAK 28(XQ27.1) MUTATED 17 64.4 (7.4)
AMP PEAK 28(XQ27.1) WILD-TYPE 454 60.8 (6.8)

Figure S254.  Get High-res Image Gene #28: 'amp_xq27.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'amp_xq27.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.0679 (Fisher's exact test), Q value = 0.14

Table S255.  Gene #28: 'amp_xq27.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
AMP PEAK 28(XQ27.1) MUTATED 6 9 2
AMP PEAK 28(XQ27.1) WILD-TYPE 182 272 8

Figure S255.  Get High-res Image Gene #28: 'amp_xq27.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'amp_xq27.1' versus 'GLEASON_SCORE'

P value = 0.134 (Wilcoxon-test), Q value = 0.24

Table S256.  Gene #28: 'amp_xq27.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
AMP PEAK 28(XQ27.1) MUTATED 17 7.9 (1.0)
AMP PEAK 28(XQ27.1) WILD-TYPE 465 7.6 (1.0)

Figure S256.  Get High-res Image Gene #28: 'amp_xq27.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_1p31.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.0126 (Fisher's exact test), Q value = 0.037

Table S257.  Gene #29: 'del_1p31.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 1(1P31.3) MUTATED 13 42 2
DEL PEAK 1(1P31.3) WILD-TYPE 175 239 8

Figure S257.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_1p31.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0615 (Fisher's exact test), Q value = 0.13

Table S258.  Gene #29: 'del_1p31.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 1(1P31.3) MUTATED 29 24 1 2
DEL PEAK 1(1P31.3) WILD-TYPE 281 114 4 13

Figure S258.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_1p31.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.131 (Wilcoxon-test), Q value = 0.23

Table S259.  Gene #29: 'del_1p31.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 1(1P31.3) MUTATED 49 0.6 (1.1)
DEL PEAK 1(1P31.3) WILD-TYPE 346 0.4 (1.4)

Figure S259.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_1p31.3' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000458 (Wilcoxon-test), Q value = 0.0027

Table S260.  Gene #29: 'del_1p31.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 1(1P31.3) MUTATED 57 8.0 (1.1)
DEL PEAK 1(1P31.3) WILD-TYPE 425 7.5 (1.0)

Figure S260.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_1p31.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0214 (Wilcoxon-test), Q value = 0.057

Table S261.  Gene #29: 'del_1p31.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 1(1P31.3) MUTATED 57 3.9 (0.7)
DEL PEAK 1(1P31.3) WILD-TYPE 425 3.7 (0.7)

Figure S261.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_1p31.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0016 (Wilcoxon-test), Q value = 0.0071

Table S262.  Gene #29: 'del_1p31.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 1(1P31.3) MUTATED 57 4.1 (0.7)
DEL PEAK 1(1P31.3) WILD-TYPE 425 3.8 (0.7)

Figure S262.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_1p31.3' versus 'GLEASON_SCORE'

P value = 0.000382 (Wilcoxon-test), Q value = 0.0024

Table S263.  Gene #29: 'del_1p31.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 1(1P31.3) MUTATED 57 8.1 (1.1)
DEL PEAK 1(1P31.3) WILD-TYPE 425 7.5 (1.0)

Figure S263.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_1p31.3' versus 'PSA_VALUE'

P value = 0.131 (Wilcoxon-test), Q value = 0.23

Table S264.  Gene #29: 'del_1p31.3' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 1(1P31.3) MUTATED 47 1.3 (2.9)
DEL PEAK 1(1P31.3) WILD-TYPE 379 1.1 (4.3)

Figure S264.  Get High-res Image Gene #29: 'del_1p31.3' versus Clinical Feature #13: 'PSA_VALUE'

'del_1p22.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.0035 (Fisher's exact test), Q value = 0.013

Table S265.  Gene #30: 'del_1p22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 2(1P22.1) MUTATED 11 42 2
DEL PEAK 2(1P22.1) WILD-TYPE 177 239 8

Figure S265.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_1p22.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0885 (Fisher's exact test), Q value = 0.17

Table S266.  Gene #30: 'del_1p22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 2(1P22.1) MUTATED 28 19 0 4
DEL PEAK 2(1P22.1) WILD-TYPE 282 119 5 11

Figure S266.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_1p22.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.06 (Wilcoxon-test), Q value = 0.13

Table S267.  Gene #30: 'del_1p22.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 2(1P22.1) MUTATED 45 0.6 (1.4)
DEL PEAK 2(1P22.1) WILD-TYPE 350 0.4 (1.4)

Figure S267.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_1p22.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00337 (Wilcoxon-test), Q value = 0.012

Table S268.  Gene #30: 'del_1p22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 2(1P22.1) MUTATED 55 7.9 (1.0)
DEL PEAK 2(1P22.1) WILD-TYPE 427 7.5 (1.0)

Figure S268.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_1p22.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00493 (Wilcoxon-test), Q value = 0.016

Table S269.  Gene #30: 'del_1p22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 2(1P22.1) MUTATED 55 3.9 (0.7)
DEL PEAK 2(1P22.1) WILD-TYPE 427 3.7 (0.7)

Figure S269.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_1p22.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.122 (Wilcoxon-test), Q value = 0.22

Table S270.  Gene #30: 'del_1p22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 2(1P22.1) MUTATED 55 4.0 (0.7)
DEL PEAK 2(1P22.1) WILD-TYPE 427 3.8 (0.7)

Figure S270.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_1p22.1' versus 'GLEASON_SCORE'

P value = 0.000608 (Wilcoxon-test), Q value = 0.0033

Table S271.  Gene #30: 'del_1p22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 2(1P22.1) MUTATED 55 8.0 (1.0)
DEL PEAK 2(1P22.1) WILD-TYPE 427 7.5 (1.0)

Figure S271.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_1p22.1' versus 'PSA_RESULT_PREOP'

P value = 0.00406 (Wilcoxon-test), Q value = 0.014

Table S272.  Gene #30: 'del_1p22.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 2(1P22.1) MUTATED 55 12.7 (11.0)
DEL PEAK 2(1P22.1) WILD-TYPE 424 10.5 (11.7)

Figure S272.  Get High-res Image Gene #30: 'del_1p22.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_1q23.1' versus 'YEARS_TO_BIRTH'

P value = 0.123 (Wilcoxon-test), Q value = 0.22

Table S273.  Gene #31: 'del_1q23.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 3(1Q23.1) MUTATED 27 62.6 (6.4)
DEL PEAK 3(1Q23.1) WILD-TYPE 444 60.8 (6.8)

Figure S273.  Get High-res Image Gene #31: 'del_1q23.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_1q42.3' versus 'Time to Death'

P value = 0.000113 (logrank test), Q value = 9e-04

Table S274.  Gene #32: 'del_1q42.3' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 481 8 0.7 - 165.2 (26.7)
DEL PEAK 4(1Q42.3) MUTATED 46 5 0.7 - 122.2 (28.4)
DEL PEAK 4(1Q42.3) WILD-TYPE 435 3 0.8 - 165.2 (26.0)

Figure S274.  Get High-res Image Gene #32: 'del_1q42.3' versus Clinical Feature #1: 'Time to Death'

'del_1q42.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0127 (Fisher's exact test), Q value = 0.037

Table S275.  Gene #32: 'del_1q42.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 4(1Q42.3) MUTATED 20 22 0 2
DEL PEAK 4(1Q42.3) WILD-TYPE 290 116 5 13

Figure S275.  Get High-res Image Gene #32: 'del_1q42.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_1q42.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.106 (Wilcoxon-test), Q value = 0.2

Table S276.  Gene #32: 'del_1q42.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 4(1Q42.3) MUTATED 39 0.7 (1.6)
DEL PEAK 4(1Q42.3) WILD-TYPE 356 0.4 (1.3)

Figure S276.  Get High-res Image Gene #32: 'del_1q42.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_1q42.3' versus 'GLEASON_SCORE_COMBINED'

P value = 0.128 (Wilcoxon-test), Q value = 0.23

Table S277.  Gene #32: 'del_1q42.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 4(1Q42.3) MUTATED 46 7.7 (0.9)
DEL PEAK 4(1Q42.3) WILD-TYPE 436 7.5 (1.0)

Figure S277.  Get High-res Image Gene #32: 'del_1q42.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_1q42.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0315 (Wilcoxon-test), Q value = 0.076

Table S278.  Gene #32: 'del_1q42.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 4(1Q42.3) MUTATED 46 3.9 (0.7)
DEL PEAK 4(1Q42.3) WILD-TYPE 436 3.7 (0.7)

Figure S278.  Get High-res Image Gene #32: 'del_1q42.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_1q42.3' versus 'GLEASON_SCORE'

P value = 0.0572 (Wilcoxon-test), Q value = 0.12

Table S279.  Gene #32: 'del_1q42.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 4(1Q42.3) MUTATED 46 7.8 (1.0)
DEL PEAK 4(1Q42.3) WILD-TYPE 436 7.6 (1.0)

Figure S279.  Get High-res Image Gene #32: 'del_1q42.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_1q42.3' versus 'PSA_VALUE'

P value = 0.0826 (Wilcoxon-test), Q value = 0.16

Table S280.  Gene #32: 'del_1q42.3' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 4(1Q42.3) MUTATED 38 2.6 (7.4)
DEL PEAK 4(1Q42.3) WILD-TYPE 388 0.9 (3.7)

Figure S280.  Get High-res Image Gene #32: 'del_1q42.3' versus Clinical Feature #13: 'PSA_VALUE'

'del_2p21' versus 'YEARS_TO_BIRTH'

P value = 0.126 (Wilcoxon-test), Q value = 0.23

Table S281.  Gene #33: 'del_2p21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 5(2P21) MUTATED 44 62.4 (6.5)
DEL PEAK 5(2P21) WILD-TYPE 427 60.7 (6.8)

Figure S281.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_2p21' versus 'PATHOLOGY_T_STAGE'

P value = 0.00042 (Fisher's exact test), Q value = 0.0026

Table S282.  Gene #33: 'del_2p21' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 5(2P21) MUTATED 7 35 3
DEL PEAK 5(2P21) WILD-TYPE 181 246 7

Figure S282.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_2p21' versus 'PATHOLOGY_N_STAGE'

P value = 0.0371 (Fisher's exact test), Q value = 0.087

Table S283.  Gene #33: 'del_2p21' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 5(2P21) MUTATED 30 13
DEL PEAK 5(2P21) WILD-TYPE 308 62

Figure S283.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_2p21' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0418 (Fisher's exact test), Q value = 0.095

Table S284.  Gene #33: 'del_2p21' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 5(2P21) MUTATED 21 19 1 2
DEL PEAK 5(2P21) WILD-TYPE 289 119 4 13

Figure S284.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_2p21' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0508 (Wilcoxon-test), Q value = 0.11

Table S285.  Gene #33: 'del_2p21' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 5(2P21) MUTATED 42 0.6 (1.3)
DEL PEAK 5(2P21) WILD-TYPE 353 0.4 (1.4)

Figure S285.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_2p21' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00188 (Wilcoxon-test), Q value = 0.0078

Table S286.  Gene #33: 'del_2p21' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 5(2P21) MUTATED 45 8.0 (1.1)
DEL PEAK 5(2P21) WILD-TYPE 437 7.5 (1.0)

Figure S286.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_2p21' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00328 (Wilcoxon-test), Q value = 0.012

Table S287.  Gene #33: 'del_2p21' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 5(2P21) MUTATED 45 4.0 (0.7)
DEL PEAK 5(2P21) WILD-TYPE 437 3.7 (0.7)

Figure S287.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_2p21' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.075 (Wilcoxon-test), Q value = 0.15

Table S288.  Gene #33: 'del_2p21' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 5(2P21) MUTATED 45 4.0 (0.7)
DEL PEAK 5(2P21) WILD-TYPE 437 3.8 (0.7)

Figure S288.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_2p21' versus 'GLEASON_SCORE'

P value = 0.00185 (Wilcoxon-test), Q value = 0.0078

Table S289.  Gene #33: 'del_2p21' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 5(2P21) MUTATED 45 8.0 (1.0)
DEL PEAK 5(2P21) WILD-TYPE 437 7.5 (1.0)

Figure S289.  Get High-res Image Gene #33: 'del_2p21' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_2q22.1' versus 'YEARS_TO_BIRTH'

P value = 8.44e-06 (Wilcoxon-test), Q value = 0.00012

Table S290.  Gene #34: 'del_2q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 6(2Q22.1) MUTATED 89 63.7 (5.8)
DEL PEAK 6(2Q22.1) WILD-TYPE 382 60.2 (6.9)

Figure S290.  Get High-res Image Gene #34: 'del_2q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_2q22.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.125 (Fisher's exact test), Q value = 0.23

Table S291.  Gene #34: 'del_2q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 6(2Q22.1) MUTATED 28 59 3
DEL PEAK 6(2Q22.1) WILD-TYPE 160 222 7

Figure S291.  Get High-res Image Gene #34: 'del_2q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_2q22.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0144 (Wilcoxon-test), Q value = 0.041

Table S292.  Gene #34: 'del_2q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 6(2Q22.1) MUTATED 90 7.8 (1.1)
DEL PEAK 6(2Q22.1) WILD-TYPE 392 7.5 (1.0)

Figure S292.  Get High-res Image Gene #34: 'del_2q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_2q22.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000754 (Wilcoxon-test), Q value = 0.0039

Table S293.  Gene #34: 'del_2q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 6(2Q22.1) MUTATED 90 3.9 (0.7)
DEL PEAK 6(2Q22.1) WILD-TYPE 392 3.6 (0.7)

Figure S293.  Get High-res Image Gene #34: 'del_2q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_2q22.1' versus 'GLEASON_SCORE'

P value = 0.0133 (Wilcoxon-test), Q value = 0.039

Table S294.  Gene #34: 'del_2q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 6(2Q22.1) MUTATED 90 7.8 (1.0)
DEL PEAK 6(2Q22.1) WILD-TYPE 392 7.5 (1.0)

Figure S294.  Get High-res Image Gene #34: 'del_2q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_2q22.3' versus 'YEARS_TO_BIRTH'

P value = 0.00173 (Wilcoxon-test), Q value = 0.0074

Table S295.  Gene #35: 'del_2q22.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 7(2Q22.3) MUTATED 82 62.9 (6.5)
DEL PEAK 7(2Q22.3) WILD-TYPE 389 60.5 (6.8)

Figure S295.  Get High-res Image Gene #35: 'del_2q22.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_2q22.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0167 (Wilcoxon-test), Q value = 0.047

Table S296.  Gene #35: 'del_2q22.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 7(2Q22.3) MUTATED 83 3.8 (0.7)
DEL PEAK 7(2Q22.3) WILD-TYPE 399 3.7 (0.7)

Figure S296.  Get High-res Image Gene #35: 'del_2q22.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_2q22.3' versus 'GLEASON_SCORE'

P value = 0.1 (Wilcoxon-test), Q value = 0.19

Table S297.  Gene #35: 'del_2q22.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 7(2Q22.3) MUTATED 83 7.8 (1.1)
DEL PEAK 7(2Q22.3) WILD-TYPE 399 7.5 (1.0)

Figure S297.  Get High-res Image Gene #35: 'del_2q22.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_2q22.3' versus 'PSA_VALUE'

P value = 0.14 (Wilcoxon-test), Q value = 0.25

Table S298.  Gene #35: 'del_2q22.3' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 7(2Q22.3) MUTATED 71 0.7 (2.4)
DEL PEAK 7(2Q22.3) WILD-TYPE 355 1.2 (4.4)

Figure S298.  Get High-res Image Gene #35: 'del_2q22.3' versus Clinical Feature #13: 'PSA_VALUE'

'del_3p13' versus 'YEARS_TO_BIRTH'

P value = 0.04 (Wilcoxon-test), Q value = 0.092

Table S299.  Gene #36: 'del_3p13' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 8(3P13) MUTATED 77 59.5 (7.2)
DEL PEAK 8(3P13) WILD-TYPE 394 61.2 (6.7)

Figure S299.  Get High-res Image Gene #36: 'del_3p13' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_3q29' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0541 (Wilcoxon-test), Q value = 0.12

Table S300.  Gene #37: 'del_3q29' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 9(3Q29) MUTATED 32 7.9 (1.1)
DEL PEAK 9(3Q29) WILD-TYPE 450 7.5 (1.0)

Figure S300.  Get High-res Image Gene #37: 'del_3q29' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_3q29' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0448 (Wilcoxon-test), Q value = 0.1

Table S301.  Gene #37: 'del_3q29' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 9(3Q29) MUTATED 32 3.9 (0.8)
DEL PEAK 9(3Q29) WILD-TYPE 450 3.7 (0.7)

Figure S301.  Get High-res Image Gene #37: 'del_3q29' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_3q29' versus 'GLEASON_SCORE'

P value = 0.0853 (Wilcoxon-test), Q value = 0.17

Table S302.  Gene #37: 'del_3q29' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 9(3Q29) MUTATED 32 7.9 (1.1)
DEL PEAK 9(3Q29) WILD-TYPE 450 7.6 (1.0)

Figure S302.  Get High-res Image Gene #37: 'del_3q29' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_3q29' versus 'PSA_RESULT_PREOP'

P value = 0.0812 (Wilcoxon-test), Q value = 0.16

Table S303.  Gene #37: 'del_3q29' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 9(3Q29) MUTATED 32 12.1 (8.5)
DEL PEAK 9(3Q29) WILD-TYPE 447 10.7 (11.8)

Figure S303.  Get High-res Image Gene #37: 'del_3q29' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_4q28.2' versus 'YEARS_TO_BIRTH'

P value = 0.00192 (Wilcoxon-test), Q value = 0.0078

Table S304.  Gene #38: 'del_4q28.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 10(4Q28.2) MUTATED 48 63.8 (6.1)
DEL PEAK 10(4Q28.2) WILD-TYPE 423 60.6 (6.8)

Figure S304.  Get High-res Image Gene #38: 'del_4q28.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_4q28.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.0668 (Fisher's exact test), Q value = 0.14

Table S305.  Gene #38: 'del_4q28.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 10(4Q28.2) MUTATED 15 31 3
DEL PEAK 10(4Q28.2) WILD-TYPE 173 250 7

Figure S305.  Get High-res Image Gene #38: 'del_4q28.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_4q28.2' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00116 (Wilcoxon-test), Q value = 0.0055

Table S306.  Gene #38: 'del_4q28.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 10(4Q28.2) MUTATED 49 8.0 (0.9)
DEL PEAK 10(4Q28.2) WILD-TYPE 433 7.5 (1.0)

Figure S306.  Get High-res Image Gene #38: 'del_4q28.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_4q28.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000821 (Wilcoxon-test), Q value = 0.0041

Table S307.  Gene #38: 'del_4q28.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 10(4Q28.2) MUTATED 49 4.0 (0.7)
DEL PEAK 10(4Q28.2) WILD-TYPE 433 3.7 (0.7)

Figure S307.  Get High-res Image Gene #38: 'del_4q28.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_4q28.2' versus 'GLEASON_SCORE'

P value = 0.000524 (Wilcoxon-test), Q value = 0.0029

Table S308.  Gene #38: 'del_4q28.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 10(4Q28.2) MUTATED 49 8.1 (1.0)
DEL PEAK 10(4Q28.2) WILD-TYPE 433 7.5 (1.0)

Figure S308.  Get High-res Image Gene #38: 'del_4q28.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_5q11.2' versus 'YEARS_TO_BIRTH'

P value = 0.0203 (Wilcoxon-test), Q value = 0.055

Table S309.  Gene #39: 'del_5q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 11(5Q11.2) MUTATED 96 62.4 (6.2)
DEL PEAK 11(5Q11.2) WILD-TYPE 375 60.5 (6.9)

Figure S309.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_5q11.2' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S310.  Gene #39: 'del_5q11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 11(5Q11.2) MUTATED 16 75 5
DEL PEAK 11(5Q11.2) WILD-TYPE 172 206 5

Figure S310.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_5q11.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.000294 (Fisher's exact test), Q value = 0.002

Table S311.  Gene #39: 'del_5q11.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 11(5Q11.2) MUTATED 61 29
DEL PEAK 11(5Q11.2) WILD-TYPE 277 46

Figure S311.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_5q11.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0298 (Fisher's exact test), Q value = 0.073

Table S312.  Gene #39: 'del_5q11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 11(5Q11.2) MUTATED 50 38 1 4
DEL PEAK 11(5Q11.2) WILD-TYPE 260 100 4 11

Figure S312.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_5q11.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 7.85e-06 (Wilcoxon-test), Q value = 0.00012

Table S313.  Gene #39: 'del_5q11.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 11(5Q11.2) MUTATED 82 1.0 (2.2)
DEL PEAK 11(5Q11.2) WILD-TYPE 313 0.3 (1.0)

Figure S313.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_5q11.2' versus 'GLEASON_SCORE_COMBINED'

P value = 1.58e-08 (Wilcoxon-test), Q value = 5.9e-07

Table S314.  Gene #39: 'del_5q11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 11(5Q11.2) MUTATED 96 8.1 (1.0)
DEL PEAK 11(5Q11.2) WILD-TYPE 386 7.4 (1.0)

Figure S314.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_5q11.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 1.49e-08 (Wilcoxon-test), Q value = 5.9e-07

Table S315.  Gene #39: 'del_5q11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 11(5Q11.2) MUTATED 96 4.0 (0.7)
DEL PEAK 11(5Q11.2) WILD-TYPE 386 3.6 (0.7)

Figure S315.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_5q11.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0125 (Wilcoxon-test), Q value = 0.037

Table S316.  Gene #39: 'del_5q11.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 11(5Q11.2) MUTATED 96 4.0 (0.7)
DEL PEAK 11(5Q11.2) WILD-TYPE 386 3.8 (0.7)

Figure S316.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_5q11.2' versus 'GLEASON_SCORE'

P value = 4.43e-10 (Wilcoxon-test), Q value = 3.7e-08

Table S317.  Gene #39: 'del_5q11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 11(5Q11.2) MUTATED 96 8.2 (1.0)
DEL PEAK 11(5Q11.2) WILD-TYPE 386 7.4 (1.0)

Figure S317.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_5q11.2' versus 'PSA_RESULT_PREOP'

P value = 0.00044 (Wilcoxon-test), Q value = 0.0027

Table S318.  Gene #39: 'del_5q11.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 11(5Q11.2) MUTATED 96 12.6 (10.4)
DEL PEAK 11(5Q11.2) WILD-TYPE 383 10.3 (11.9)

Figure S318.  Get High-res Image Gene #39: 'del_5q11.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_5q13.2' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S319.  Gene #40: 'del_5q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 12(5Q13.2) MUTATED 15 76 5
DEL PEAK 12(5Q13.2) WILD-TYPE 173 205 5

Figure S319.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_5q13.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0132 (Fisher's exact test), Q value = 0.039

Table S320.  Gene #40: 'del_5q13.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 12(5Q13.2) MUTATED 66 25
DEL PEAK 12(5Q13.2) WILD-TYPE 272 50

Figure S320.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_5q13.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00172 (Wilcoxon-test), Q value = 0.0074

Table S321.  Gene #40: 'del_5q13.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 12(5Q13.2) MUTATED 83 1.0 (2.5)
DEL PEAK 12(5Q13.2) WILD-TYPE 312 0.3 (0.8)

Figure S321.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_5q13.2' versus 'GLEASON_SCORE_COMBINED'

P value = 2.49e-08 (Wilcoxon-test), Q value = 7.3e-07

Table S322.  Gene #40: 'del_5q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 12(5Q13.2) MUTATED 96 8.1 (1.0)
DEL PEAK 12(5Q13.2) WILD-TYPE 386 7.4 (1.0)

Figure S322.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_5q13.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 1.74e-07 (Wilcoxon-test), Q value = 3.9e-06

Table S323.  Gene #40: 'del_5q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 12(5Q13.2) MUTATED 96 4.0 (0.6)
DEL PEAK 12(5Q13.2) WILD-TYPE 386 3.6 (0.7)

Figure S323.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_5q13.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00289 (Wilcoxon-test), Q value = 0.011

Table S324.  Gene #40: 'del_5q13.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 12(5Q13.2) MUTATED 96 4.1 (0.7)
DEL PEAK 12(5Q13.2) WILD-TYPE 386 3.8 (0.7)

Figure S324.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_5q13.2' versus 'GLEASON_SCORE'

P value = 1.62e-08 (Wilcoxon-test), Q value = 5.9e-07

Table S325.  Gene #40: 'del_5q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 12(5Q13.2) MUTATED 96 8.1 (1.0)
DEL PEAK 12(5Q13.2) WILD-TYPE 386 7.5 (1.0)

Figure S325.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_5q13.2' versus 'PSA_RESULT_PREOP'

P value = 0.00373 (Wilcoxon-test), Q value = 0.013

Table S326.  Gene #40: 'del_5q13.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 12(5Q13.2) MUTATED 96 12.1 (10.2)
DEL PEAK 12(5Q13.2) WILD-TYPE 383 10.5 (12.0)

Figure S326.  Get High-res Image Gene #40: 'del_5q13.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_5q21.1' versus 'YEARS_TO_BIRTH'

P value = 0.0402 (Wilcoxon-test), Q value = 0.092

Table S327.  Gene #41: 'del_5q21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 13(5Q21.1) MUTATED 104 62.1 (6.0)
DEL PEAK 13(5Q21.1) WILD-TYPE 367 60.5 (7.0)

Figure S327.  Get High-res Image Gene #41: 'del_5q21.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_5q21.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.0288 (Fisher's exact test), Q value = 0.071

Table S328.  Gene #41: 'del_5q21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 13(5Q21.1) MUTATED 30 72 3
DEL PEAK 13(5Q21.1) WILD-TYPE 158 209 7

Figure S328.  Get High-res Image Gene #41: 'del_5q21.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_5q21.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000134 (Wilcoxon-test), Q value = 0.001

Table S329.  Gene #41: 'del_5q21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 13(5Q21.1) MUTATED 105 7.9 (0.9)
DEL PEAK 13(5Q21.1) WILD-TYPE 377 7.5 (1.0)

Figure S329.  Get High-res Image Gene #41: 'del_5q21.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_5q21.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 2.01e-06 (Wilcoxon-test), Q value = 3.7e-05

Table S330.  Gene #41: 'del_5q21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 13(5Q21.1) MUTATED 105 4.0 (0.6)
DEL PEAK 13(5Q21.1) WILD-TYPE 377 3.6 (0.7)

Figure S330.  Get High-res Image Gene #41: 'del_5q21.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_5q21.1' versus 'GLEASON_SCORE'

P value = 0.00292 (Wilcoxon-test), Q value = 0.011

Table S331.  Gene #41: 'del_5q21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 13(5Q21.1) MUTATED 105 7.8 (1.0)
DEL PEAK 13(5Q21.1) WILD-TYPE 377 7.5 (1.0)

Figure S331.  Get High-res Image Gene #41: 'del_5q21.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_5q21.1' versus 'PSA_RESULT_PREOP'

P value = 0.0636 (Wilcoxon-test), Q value = 0.14

Table S332.  Gene #41: 'del_5q21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 13(5Q21.1) MUTATED 104 12.1 (11.9)
DEL PEAK 13(5Q21.1) WILD-TYPE 375 10.4 (11.6)

Figure S332.  Get High-res Image Gene #41: 'del_5q21.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_5q21.1' versus 'PSA_VALUE'

P value = 0.127 (Wilcoxon-test), Q value = 0.23

Table S333.  Gene #41: 'del_5q21.1' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 13(5Q21.1) MUTATED 89 1.7 (5.7)
DEL PEAK 13(5Q21.1) WILD-TYPE 337 0.9 (3.6)

Figure S333.  Get High-res Image Gene #41: 'del_5q21.1' versus Clinical Feature #13: 'PSA_VALUE'

'del_6p25.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.017 (Fisher's exact test), Q value = 0.047

Table S334.  Gene #42: 'del_6p25.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 14(6P25.1) MUTATED 10 28 3
DEL PEAK 14(6P25.1) WILD-TYPE 178 253 7

Figure S334.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_6p25.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.00802 (Fisher's exact test), Q value = 0.025

Table S335.  Gene #42: 'del_6p25.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 14(6P25.1) MUTATED 26 14
DEL PEAK 14(6P25.1) WILD-TYPE 312 61

Figure S335.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_6p25.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00158 (Wilcoxon-test), Q value = 0.007

Table S336.  Gene #42: 'del_6p25.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 14(6P25.1) MUTATED 36 0.7 (1.0)
DEL PEAK 14(6P25.1) WILD-TYPE 359 0.4 (1.4)

Figure S336.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_6p25.1' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000136 (Wilcoxon-test), Q value = 0.001

Table S337.  Gene #42: 'del_6p25.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 14(6P25.1) MUTATED 41 8.1 (0.9)
DEL PEAK 14(6P25.1) WILD-TYPE 441 7.5 (1.0)

Figure S337.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_6p25.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00172 (Wilcoxon-test), Q value = 0.0074

Table S338.  Gene #42: 'del_6p25.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 14(6P25.1) MUTATED 41 4.0 (0.7)
DEL PEAK 14(6P25.1) WILD-TYPE 441 3.7 (0.7)

Figure S338.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_6p25.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0177 (Wilcoxon-test), Q value = 0.049

Table S339.  Gene #42: 'del_6p25.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 14(6P25.1) MUTATED 41 4.1 (0.6)
DEL PEAK 14(6P25.1) WILD-TYPE 441 3.8 (0.7)

Figure S339.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_6p25.1' versus 'GLEASON_SCORE'

P value = 8.95e-05 (Wilcoxon-test), Q value = 0.00073

Table S340.  Gene #42: 'del_6p25.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 14(6P25.1) MUTATED 41 8.2 (0.9)
DEL PEAK 14(6P25.1) WILD-TYPE 441 7.5 (1.0)

Figure S340.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_6p25.1' versus 'RACE'

P value = 0.00661 (Fisher's exact test), Q value = 0.021

Table S341.  Gene #42: 'del_6p25.1' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
DEL PEAK 14(6P25.1) MUTATED 2 1 11
DEL PEAK 14(6P25.1) WILD-TYPE 0 6 135

Figure S341.  Get High-res Image Gene #42: 'del_6p25.1' versus Clinical Feature #14: 'RACE'

'del_6q14.3' versus 'YEARS_TO_BIRTH'

P value = 0.00204 (Wilcoxon-test), Q value = 0.0081

Table S342.  Gene #43: 'del_6q14.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 15(6Q14.3) MUTATED 169 62.2 (6.3)
DEL PEAK 15(6Q14.3) WILD-TYPE 302 60.2 (7.0)

Figure S342.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_6q14.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.0733 (Fisher's exact test), Q value = 0.15

Table S343.  Gene #43: 'del_6q14.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 15(6Q14.3) MUTATED 57 111 5
DEL PEAK 15(6Q14.3) WILD-TYPE 131 170 5

Figure S343.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_6q14.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.0243 (Fisher's exact test), Q value = 0.062

Table S344.  Gene #43: 'del_6q14.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 15(6Q14.3) MUTATED 117 37
DEL PEAK 15(6Q14.3) WILD-TYPE 221 38

Figure S344.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_6q14.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00033 (Fisher's exact test), Q value = 0.0022

Table S345.  Gene #43: 'del_6q14.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 15(6Q14.3) MUTATED 91 63 2 10
DEL PEAK 15(6Q14.3) WILD-TYPE 219 75 3 5

Figure S345.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_6q14.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0154 (Wilcoxon-test), Q value = 0.044

Table S346.  Gene #43: 'del_6q14.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 15(6Q14.3) MUTATED 148 0.5 (1.3)
DEL PEAK 15(6Q14.3) WILD-TYPE 247 0.4 (1.4)

Figure S346.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_6q14.3' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000745 (Wilcoxon-test), Q value = 0.0038

Table S347.  Gene #43: 'del_6q14.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 15(6Q14.3) MUTATED 173 7.7 (1.0)
DEL PEAK 15(6Q14.3) WILD-TYPE 309 7.5 (1.0)

Figure S347.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_6q14.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000428 (Wilcoxon-test), Q value = 0.0026

Table S348.  Gene #43: 'del_6q14.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 15(6Q14.3) MUTATED 173 3.8 (0.7)
DEL PEAK 15(6Q14.3) WILD-TYPE 309 3.6 (0.7)

Figure S348.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_6q14.3' versus 'GLEASON_SCORE'

P value = 0.000668 (Wilcoxon-test), Q value = 0.0035

Table S349.  Gene #43: 'del_6q14.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 15(6Q14.3) MUTATED 173 7.8 (1.0)
DEL PEAK 15(6Q14.3) WILD-TYPE 309 7.5 (1.0)

Figure S349.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_6q14.3' versus 'PSA_RESULT_PREOP'

P value = 0.0052 (Wilcoxon-test), Q value = 0.017

Table S350.  Gene #43: 'del_6q14.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 15(6Q14.3) MUTATED 172 12.9 (13.9)
DEL PEAK 15(6Q14.3) WILD-TYPE 307 9.6 (10.0)

Figure S350.  Get High-res Image Gene #43: 'del_6q14.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_7q31.33' versus 'PATHOLOGY_N_STAGE'

P value = 0.102 (Fisher's exact test), Q value = 0.19

Table S351.  Gene #44: 'del_7q31.33' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 16(7Q31.33) MUTATED 17 8
DEL PEAK 16(7Q31.33) WILD-TYPE 321 67

Figure S351.  Get High-res Image Gene #44: 'del_7q31.33' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_7q31.33' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0348 (Wilcoxon-test), Q value = 0.083

Table S352.  Gene #44: 'del_7q31.33' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 16(7Q31.33) MUTATED 23 0.8 (1.5)
DEL PEAK 16(7Q31.33) WILD-TYPE 372 0.4 (1.4)

Figure S352.  Get High-res Image Gene #44: 'del_7q31.33' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_7q31.33' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.122 (Wilcoxon-test), Q value = 0.22

Table S353.  Gene #44: 'del_7q31.33' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 16(7Q31.33) MUTATED 28 3.9 (0.6)
DEL PEAK 16(7Q31.33) WILD-TYPE 454 3.7 (0.7)

Figure S353.  Get High-res Image Gene #44: 'del_7q31.33' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_7q31.33' versus 'GLEASON_SCORE'

P value = 0.0729 (Wilcoxon-test), Q value = 0.15

Table S354.  Gene #44: 'del_7q31.33' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 16(7Q31.33) MUTATED 28 7.9 (1.1)
DEL PEAK 16(7Q31.33) WILD-TYPE 454 7.6 (1.0)

Figure S354.  Get High-res Image Gene #44: 'del_7q31.33' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_8p23.2' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S355.  Gene #45: 'del_8p23.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 17(8P23.2) MUTATED 57 155 6
DEL PEAK 17(8P23.2) WILD-TYPE 131 126 4

Figure S355.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_8p23.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.0103 (Fisher's exact test), Q value = 0.031

Table S356.  Gene #45: 'del_8p23.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 17(8P23.2) MUTATED 146 45
DEL PEAK 17(8P23.2) WILD-TYPE 192 30

Figure S356.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_8p23.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00502 (Wilcoxon-test), Q value = 0.017

Table S357.  Gene #45: 'del_8p23.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 17(8P23.2) MUTATED 182 0.6 (1.6)
DEL PEAK 17(8P23.2) WILD-TYPE 213 0.3 (1.1)

Figure S357.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_8p23.2' versus 'GLEASON_SCORE_COMBINED'

P value = 0.00146 (Wilcoxon-test), Q value = 0.0067

Table S358.  Gene #45: 'del_8p23.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 17(8P23.2) MUTATED 218 7.7 (1.1)
DEL PEAK 17(8P23.2) WILD-TYPE 264 7.4 (1.0)

Figure S358.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_8p23.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 7.83e-05 (Wilcoxon-test), Q value = 0.00066

Table S359.  Gene #45: 'del_8p23.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 17(8P23.2) MUTATED 218 3.8 (0.7)
DEL PEAK 17(8P23.2) WILD-TYPE 264 3.6 (0.7)

Figure S359.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_8p23.2' versus 'GLEASON_SCORE'

P value = 0.00453 (Wilcoxon-test), Q value = 0.015

Table S360.  Gene #45: 'del_8p23.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 17(8P23.2) MUTATED 218 7.7 (1.0)
DEL PEAK 17(8P23.2) WILD-TYPE 264 7.5 (1.0)

Figure S360.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_8p23.2' versus 'PSA_RESULT_PREOP'

P value = 0.027 (Wilcoxon-test), Q value = 0.068

Table S361.  Gene #45: 'del_8p23.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 17(8P23.2) MUTATED 217 12.4 (14.3)
DEL PEAK 17(8P23.2) WILD-TYPE 262 9.5 (8.7)

Figure S361.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_8p23.2' versus 'PSA_VALUE'

P value = 0.0964 (Wilcoxon-test), Q value = 0.18

Table S362.  Gene #45: 'del_8p23.2' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 17(8P23.2) MUTATED 192 1.7 (5.6)
DEL PEAK 17(8P23.2) WILD-TYPE 234 0.6 (2.3)

Figure S362.  Get High-res Image Gene #45: 'del_8p23.2' versus Clinical Feature #13: 'PSA_VALUE'

'del_8p21.3' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S363.  Gene #46: 'del_8p21.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 18(8P21.3) MUTATED 81 197 8
DEL PEAK 18(8P21.3) WILD-TYPE 107 84 2

Figure S363.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_8p21.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.00158 (Fisher's exact test), Q value = 0.007

Table S364.  Gene #46: 'del_8p21.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 18(8P21.3) MUTATED 195 58
DEL PEAK 18(8P21.3) WILD-TYPE 143 17

Figure S364.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_8p21.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.137 (Fisher's exact test), Q value = 0.24

Table S365.  Gene #46: 'del_8p21.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 18(8P21.3) MUTATED 172 92 3 10
DEL PEAK 18(8P21.3) WILD-TYPE 138 46 2 5

Figure S365.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_8p21.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00092 (Wilcoxon-test), Q value = 0.0045

Table S366.  Gene #46: 'del_8p21.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 18(8P21.3) MUTATED 241 0.6 (1.6)
DEL PEAK 18(8P21.3) WILD-TYPE 154 0.2 (0.8)

Figure S366.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_8p21.3' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000213 (Wilcoxon-test), Q value = 0.0015

Table S367.  Gene #46: 'del_8p21.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 18(8P21.3) MUTATED 286 7.7 (1.0)
DEL PEAK 18(8P21.3) WILD-TYPE 196 7.4 (1.0)

Figure S367.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_8p21.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 6.83e-06 (Wilcoxon-test), Q value = 1e-04

Table S368.  Gene #46: 'del_8p21.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 18(8P21.3) MUTATED 286 3.8 (0.7)
DEL PEAK 18(8P21.3) WILD-TYPE 196 3.5 (0.7)

Figure S368.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_8p21.3' versus 'GLEASON_SCORE'

P value = 0.00168 (Wilcoxon-test), Q value = 0.0073

Table S369.  Gene #46: 'del_8p21.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 18(8P21.3) MUTATED 286 7.7 (1.0)
DEL PEAK 18(8P21.3) WILD-TYPE 196 7.4 (1.0)

Figure S369.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_8p21.3' versus 'PSA_RESULT_PREOP'

P value = 0.000112 (Wilcoxon-test), Q value = 9e-04

Table S370.  Gene #46: 'del_8p21.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 18(8P21.3) MUTATED 284 12.1 (13.1)
DEL PEAK 18(8P21.3) WILD-TYPE 195 8.8 (8.9)

Figure S370.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_8p21.3' versus 'PSA_VALUE'

P value = 0.0705 (Wilcoxon-test), Q value = 0.15

Table S371.  Gene #46: 'del_8p21.3' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 18(8P21.3) MUTATED 251 1.3 (4.9)
DEL PEAK 18(8P21.3) WILD-TYPE 175 0.7 (2.7)

Figure S371.  Get High-res Image Gene #46: 'del_8p21.3' versus Clinical Feature #13: 'PSA_VALUE'

'del_9p23' versus 'PATHOLOGY_T_STAGE'

P value = 0.0314 (Fisher's exact test), Q value = 0.076

Table S372.  Gene #47: 'del_9p23' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 19(9P23) MUTATED 10 31 2
DEL PEAK 19(9P23) WILD-TYPE 178 250 8

Figure S372.  Get High-res Image Gene #47: 'del_9p23' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_9p23' versus 'PATHOLOGY_N_STAGE'

P value = 0.0845 (Fisher's exact test), Q value = 0.17

Table S373.  Gene #47: 'del_9p23' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 19(9P23) MUTATED 29 12
DEL PEAK 19(9P23) WILD-TYPE 309 63

Figure S373.  Get High-res Image Gene #47: 'del_9p23' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_9p23' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.032 (Wilcoxon-test), Q value = 0.077

Table S374.  Gene #47: 'del_9p23' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 19(9P23) MUTATED 38 0.9 (2.1)
DEL PEAK 19(9P23) WILD-TYPE 357 0.4 (1.3)

Figure S374.  Get High-res Image Gene #47: 'del_9p23' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_9p23' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0162 (Wilcoxon-test), Q value = 0.045

Table S375.  Gene #47: 'del_9p23' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 19(9P23) MUTATED 43 7.9 (1.0)
DEL PEAK 19(9P23) WILD-TYPE 439 7.5 (1.0)

Figure S375.  Get High-res Image Gene #47: 'del_9p23' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_9p23' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0136 (Wilcoxon-test), Q value = 0.039

Table S376.  Gene #47: 'del_9p23' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 19(9P23) MUTATED 43 3.9 (0.7)
DEL PEAK 19(9P23) WILD-TYPE 439 3.7 (0.7)

Figure S376.  Get High-res Image Gene #47: 'del_9p23' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_9p23' versus 'GLEASON_SCORE'

P value = 0.00811 (Wilcoxon-test), Q value = 0.025

Table S377.  Gene #47: 'del_9p23' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 19(9P23) MUTATED 43 8.0 (1.1)
DEL PEAK 19(9P23) WILD-TYPE 439 7.5 (1.0)

Figure S377.  Get High-res Image Gene #47: 'del_9p23' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_10q23.31' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S378.  Gene #48: 'del_10q23.31' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 20(10Q23.31) MUTATED 37 109 6
DEL PEAK 20(10Q23.31) WILD-TYPE 151 172 4

Figure S378.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_10q23.31' versus 'PATHOLOGY_N_STAGE'

P value = 0.00305 (Fisher's exact test), Q value = 0.011

Table S379.  Gene #48: 'del_10q23.31' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 20(10Q23.31) MUTATED 107 38
DEL PEAK 20(10Q23.31) WILD-TYPE 231 37

Figure S379.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_10q23.31' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00115 (Wilcoxon-test), Q value = 0.0055

Table S380.  Gene #48: 'del_10q23.31' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 20(10Q23.31) MUTATED 139 0.7 (1.6)
DEL PEAK 20(10Q23.31) WILD-TYPE 256 0.3 (1.2)

Figure S380.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_10q23.31' versus 'GLEASON_SCORE_COMBINED'

P value = 4.15e-06 (Wilcoxon-test), Q value = 6.9e-05

Table S381.  Gene #48: 'del_10q23.31' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 20(10Q23.31) MUTATED 152 7.9 (1.0)
DEL PEAK 20(10Q23.31) WILD-TYPE 330 7.4 (1.0)

Figure S381.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_10q23.31' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000444 (Wilcoxon-test), Q value = 0.0027

Table S382.  Gene #48: 'del_10q23.31' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 20(10Q23.31) MUTATED 152 3.9 (0.7)
DEL PEAK 20(10Q23.31) WILD-TYPE 330 3.6 (0.7)

Figure S382.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_10q23.31' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00102 (Wilcoxon-test), Q value = 0.005

Table S383.  Gene #48: 'del_10q23.31' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 20(10Q23.31) MUTATED 152 4.0 (0.7)
DEL PEAK 20(10Q23.31) WILD-TYPE 330 3.8 (0.7)

Figure S383.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_10q23.31' versus 'GLEASON_SCORE'

P value = 1.72e-07 (Wilcoxon-test), Q value = 3.9e-06

Table S384.  Gene #48: 'del_10q23.31' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 20(10Q23.31) MUTATED 152 7.9 (1.0)
DEL PEAK 20(10Q23.31) WILD-TYPE 330 7.4 (1.0)

Figure S384.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_10q23.31' versus 'PSA_VALUE'

P value = 0.0115 (Wilcoxon-test), Q value = 0.034

Table S385.  Gene #48: 'del_10q23.31' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 20(10Q23.31) MUTATED 136 2.0 (6.5)
DEL PEAK 20(10Q23.31) WILD-TYPE 290 0.6 (2.3)

Figure S385.  Get High-res Image Gene #48: 'del_10q23.31' versus Clinical Feature #13: 'PSA_VALUE'

'del_11p11.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.0146 (Fisher's exact test), Q value = 0.042

Table S386.  Gene #49: 'del_11p11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 21(11P11.2) MUTATED 6 27 1
DEL PEAK 21(11P11.2) WILD-TYPE 182 254 9

Figure S386.  Get High-res Image Gene #49: 'del_11p11.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_11p11.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0372 (Fisher's exact test), Q value = 0.088

Table S387.  Gene #49: 'del_11p11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 21(11P11.2) MUTATED 15 16 0 2
DEL PEAK 21(11P11.2) WILD-TYPE 295 122 5 13

Figure S387.  Get High-res Image Gene #49: 'del_11p11.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_11p11.2' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0214 (Wilcoxon-test), Q value = 0.057

Table S388.  Gene #49: 'del_11p11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 21(11P11.2) MUTATED 34 7.9 (1.0)
DEL PEAK 21(11P11.2) WILD-TYPE 448 7.5 (1.0)

Figure S388.  Get High-res Image Gene #49: 'del_11p11.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_11p11.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0155 (Wilcoxon-test), Q value = 0.044

Table S389.  Gene #49: 'del_11p11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 21(11P11.2) MUTATED 34 3.9 (0.6)
DEL PEAK 21(11P11.2) WILD-TYPE 448 3.7 (0.7)

Figure S389.  Get High-res Image Gene #49: 'del_11p11.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_11p11.2' versus 'GLEASON_SCORE'

P value = 0.00839 (Wilcoxon-test), Q value = 0.026

Table S390.  Gene #49: 'del_11p11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 21(11P11.2) MUTATED 34 8.0 (1.0)
DEL PEAK 21(11P11.2) WILD-TYPE 448 7.6 (1.0)

Figure S390.  Get High-res Image Gene #49: 'del_11p11.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_11p11.2' versus 'PSA_RESULT_PREOP'

P value = 0.11 (Wilcoxon-test), Q value = 0.2

Table S391.  Gene #49: 'del_11p11.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 21(11P11.2) MUTATED 33 10.8 (7.1)
DEL PEAK 21(11P11.2) WILD-TYPE 446 10.8 (11.9)

Figure S391.  Get High-res Image Gene #49: 'del_11p11.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_11p11.2' versus 'RACE'

P value = 0.00387 (Fisher's exact test), Q value = 0.014

Table S392.  Gene #49: 'del_11p11.2' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
DEL PEAK 21(11P11.2) MUTATED 1 2 3
DEL PEAK 21(11P11.2) WILD-TYPE 1 5 143

Figure S392.  Get High-res Image Gene #49: 'del_11p11.2' versus Clinical Feature #14: 'RACE'

'del_11q22.3' versus 'YEARS_TO_BIRTH'

P value = 0.027 (Wilcoxon-test), Q value = 0.068

Table S393.  Gene #50: 'del_11q22.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 22(11Q22.3) MUTATED 42 63.2 (6.4)
DEL PEAK 22(11Q22.3) WILD-TYPE 429 60.7 (6.8)

Figure S393.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_11q22.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.00045 (Fisher's exact test), Q value = 0.0027

Table S394.  Gene #50: 'del_11q22.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 22(11Q22.3) MUTATED 7 33 3
DEL PEAK 22(11Q22.3) WILD-TYPE 181 248 7

Figure S394.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_11q22.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.118 (Fisher's exact test), Q value = 0.22

Table S395.  Gene #50: 'del_11q22.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 22(11Q22.3) MUTATED 26 10
DEL PEAK 22(11Q22.3) WILD-TYPE 312 65

Figure S395.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_11q22.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00287 (Fisher's exact test), Q value = 0.011

Table S396.  Gene #50: 'del_11q22.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 22(11Q22.3) MUTATED 18 23 0 0
DEL PEAK 22(11Q22.3) WILD-TYPE 292 115 5 15

Figure S396.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_11q22.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0639 (Wilcoxon-test), Q value = 0.14

Table S397.  Gene #50: 'del_11q22.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 22(11Q22.3) MUTATED 34 0.7 (1.2)
DEL PEAK 22(11Q22.3) WILD-TYPE 361 0.4 (1.4)

Figure S397.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_11q22.3' versus 'GLEASON_SCORE_COMBINED'

P value = 6.77e-06 (Wilcoxon-test), Q value = 1e-04

Table S398.  Gene #50: 'del_11q22.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 22(11Q22.3) MUTATED 43 8.3 (1.0)
DEL PEAK 22(11Q22.3) WILD-TYPE 439 7.5 (1.0)

Figure S398.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_11q22.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 2.1e-06 (Wilcoxon-test), Q value = 3.7e-05

Table S399.  Gene #50: 'del_11q22.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 22(11Q22.3) MUTATED 43 4.2 (0.7)
DEL PEAK 22(11Q22.3) WILD-TYPE 439 3.6 (0.7)

Figure S399.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_11q22.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0516 (Wilcoxon-test), Q value = 0.11

Table S400.  Gene #50: 'del_11q22.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 22(11Q22.3) MUTATED 43 4.1 (0.8)
DEL PEAK 22(11Q22.3) WILD-TYPE 439 3.8 (0.7)

Figure S400.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_11q22.3' versus 'GLEASON_SCORE'

P value = 3.74e-05 (Wilcoxon-test), Q value = 0.00036

Table S401.  Gene #50: 'del_11q22.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 22(11Q22.3) MUTATED 43 8.2 (1.0)
DEL PEAK 22(11Q22.3) WILD-TYPE 439 7.5 (1.0)

Figure S401.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_11q22.3' versus 'PSA_RESULT_PREOP'

P value = 0.013 (Wilcoxon-test), Q value = 0.038

Table S402.  Gene #50: 'del_11q22.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 22(11Q22.3) MUTATED 43 14.0 (15.1)
DEL PEAK 22(11Q22.3) WILD-TYPE 436 10.5 (11.2)

Figure S402.  Get High-res Image Gene #50: 'del_11q22.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_11q23.2' versus 'YEARS_TO_BIRTH'

P value = 0.0568 (Wilcoxon-test), Q value = 0.12

Table S403.  Gene #51: 'del_11q23.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 23(11Q23.2) MUTATED 47 62.7 (6.2)
DEL PEAK 23(11Q23.2) WILD-TYPE 424 60.7 (6.9)

Figure S403.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_11q23.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.00204 (Fisher's exact test), Q value = 0.0081

Table S404.  Gene #51: 'del_11q23.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 23(11Q23.2) MUTATED 11 33 4
DEL PEAK 23(11Q23.2) WILD-TYPE 177 248 6

Figure S404.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_11q23.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0114 (Fisher's exact test), Q value = 0.034

Table S405.  Gene #51: 'del_11q23.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 23(11Q23.2) MUTATED 21 23 0 2
DEL PEAK 23(11Q23.2) WILD-TYPE 289 115 5 13

Figure S405.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_11q23.2' versus 'GLEASON_SCORE_COMBINED'

P value = 4e-05 (Wilcoxon-test), Q value = 0.00038

Table S406.  Gene #51: 'del_11q23.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 23(11Q23.2) MUTATED 48 8.1 (1.0)
DEL PEAK 23(11Q23.2) WILD-TYPE 434 7.5 (1.0)

Figure S406.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_11q23.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000221 (Wilcoxon-test), Q value = 0.0015

Table S407.  Gene #51: 'del_11q23.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 23(11Q23.2) MUTATED 48 4.1 (0.8)
DEL PEAK 23(11Q23.2) WILD-TYPE 434 3.6 (0.7)

Figure S407.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_11q23.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0221 (Wilcoxon-test), Q value = 0.058

Table S408.  Gene #51: 'del_11q23.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 23(11Q23.2) MUTATED 48 4.1 (0.7)
DEL PEAK 23(11Q23.2) WILD-TYPE 434 3.8 (0.7)

Figure S408.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_11q23.2' versus 'GLEASON_SCORE'

P value = 4.46e-05 (Wilcoxon-test), Q value = 0.00041

Table S409.  Gene #51: 'del_11q23.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 23(11Q23.2) MUTATED 48 8.2 (1.0)
DEL PEAK 23(11Q23.2) WILD-TYPE 434 7.5 (1.0)

Figure S409.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_11q23.2' versus 'PSA_RESULT_PREOP'

P value = 0.104 (Wilcoxon-test), Q value = 0.2

Table S410.  Gene #51: 'del_11q23.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 23(11Q23.2) MUTATED 48 13.0 (14.6)
DEL PEAK 23(11Q23.2) WILD-TYPE 431 10.5 (11.3)

Figure S410.  Get High-res Image Gene #51: 'del_11q23.2' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_12p13.1' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S411.  Gene #52: 'del_12p13.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 24(12P13.1) MUTATED 23 94 5
DEL PEAK 24(12P13.1) WILD-TYPE 165 187 5

Figure S411.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_12p13.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0153 (Fisher's exact test), Q value = 0.044

Table S412.  Gene #52: 'del_12p13.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 24(12P13.1) MUTATED 86 30
DEL PEAK 24(12P13.1) WILD-TYPE 252 45

Figure S412.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_12p13.1' versus 'HISTOLOGICAL_TYPE'

P value = 0.13 (Fisher's exact test), Q value = 0.23

Table S413.  Gene #52: 'del_12p13.1' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

nPatients PROSTATE ADENOCARCINOMA OTHER SUBTYPE PROSTATE ADENOCARCINOMA ACINAR TYPE
ALL 14 468
DEL PEAK 24(12P13.1) MUTATED 6 116
DEL PEAK 24(12P13.1) WILD-TYPE 8 352

Figure S413.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #5: 'HISTOLOGICAL_TYPE'

'del_12p13.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00453 (Wilcoxon-test), Q value = 0.015

Table S414.  Gene #52: 'del_12p13.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 24(12P13.1) MUTATED 108 0.7 (1.6)
DEL PEAK 24(12P13.1) WILD-TYPE 287 0.3 (1.3)

Figure S414.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_12p13.1' versus 'GLEASON_SCORE_COMBINED'

P value = 3.09e-05 (Wilcoxon-test), Q value = 0.00031

Table S415.  Gene #52: 'del_12p13.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 24(12P13.1) MUTATED 122 7.9 (1.1)
DEL PEAK 24(12P13.1) WILD-TYPE 360 7.4 (1.0)

Figure S415.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_12p13.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 6.06e-05 (Wilcoxon-test), Q value = 0.00053

Table S416.  Gene #52: 'del_12p13.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 24(12P13.1) MUTATED 122 3.9 (0.6)
DEL PEAK 24(12P13.1) WILD-TYPE 360 3.6 (0.7)

Figure S416.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_12p13.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0122 (Wilcoxon-test), Q value = 0.036

Table S417.  Gene #52: 'del_12p13.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 24(12P13.1) MUTATED 122 4.0 (0.8)
DEL PEAK 24(12P13.1) WILD-TYPE 360 3.8 (0.6)

Figure S417.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_12p13.1' versus 'GLEASON_SCORE'

P value = 1.73e-05 (Wilcoxon-test), Q value = 0.00019

Table S418.  Gene #52: 'del_12p13.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 24(12P13.1) MUTATED 122 7.9 (1.0)
DEL PEAK 24(12P13.1) WILD-TYPE 360 7.5 (1.0)

Figure S418.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_12p13.1' versus 'PSA_RESULT_PREOP'

P value = 0.0242 (Wilcoxon-test), Q value = 0.062

Table S419.  Gene #52: 'del_12p13.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 24(12P13.1) MUTATED 121 12.4 (14.0)
DEL PEAK 24(12P13.1) WILD-TYPE 358 10.2 (10.7)

Figure S419.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_12p13.1' versus 'PSA_VALUE'

P value = 0.0177 (Wilcoxon-test), Q value = 0.049

Table S420.  Gene #52: 'del_12p13.1' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 24(12P13.1) MUTATED 107 1.3 (4.7)
DEL PEAK 24(12P13.1) WILD-TYPE 319 1.0 (4.0)

Figure S420.  Get High-res Image Gene #52: 'del_12p13.1' versus Clinical Feature #13: 'PSA_VALUE'

'del_12q24.32' versus 'PATHOLOGY_T_STAGE'

P value = 0.0039 (Fisher's exact test), Q value = 0.014

Table S421.  Gene #53: 'del_12q24.32' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 25(12Q24.32) MUTATED 7 34 1
DEL PEAK 25(12Q24.32) WILD-TYPE 181 247 9

Figure S421.  Get High-res Image Gene #53: 'del_12q24.32' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_12q24.32' versus 'PATHOLOGY_N_STAGE'

P value = 0.0468 (Fisher's exact test), Q value = 0.11

Table S422.  Gene #53: 'del_12q24.32' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 25(12Q24.32) MUTATED 27 12
DEL PEAK 25(12Q24.32) WILD-TYPE 311 63

Figure S422.  Get High-res Image Gene #53: 'del_12q24.32' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_12q24.32' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0286 (Wilcoxon-test), Q value = 0.071

Table S423.  Gene #53: 'del_12q24.32' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 25(12Q24.32) MUTATED 37 0.9 (2.6)
DEL PEAK 25(12Q24.32) WILD-TYPE 358 0.4 (1.2)

Figure S423.  Get High-res Image Gene #53: 'del_12q24.32' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_12q24.32' versus 'GLEASON_SCORE_COMBINED'

P value = 0.0585 (Wilcoxon-test), Q value = 0.13

Table S424.  Gene #53: 'del_12q24.32' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 25(12Q24.32) MUTATED 42 7.9 (1.1)
DEL PEAK 25(12Q24.32) WILD-TYPE 440 7.5 (1.0)

Figure S424.  Get High-res Image Gene #53: 'del_12q24.32' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_12q24.32' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.0747 (Wilcoxon-test), Q value = 0.15

Table S425.  Gene #53: 'del_12q24.32' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 25(12Q24.32) MUTATED 42 3.9 (0.6)
DEL PEAK 25(12Q24.32) WILD-TYPE 440 3.7 (0.7)

Figure S425.  Get High-res Image Gene #53: 'del_12q24.32' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_12q24.32' versus 'GLEASON_SCORE'

P value = 0.0615 (Wilcoxon-test), Q value = 0.13

Table S426.  Gene #53: 'del_12q24.32' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 25(12Q24.32) MUTATED 42 7.9 (1.0)
DEL PEAK 25(12Q24.32) WILD-TYPE 440 7.6 (1.0)

Figure S426.  Get High-res Image Gene #53: 'del_12q24.32' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_12q24.32' versus 'PSA_RESULT_PREOP'

P value = 0.0129 (Wilcoxon-test), Q value = 0.038

Table S427.  Gene #53: 'del_12q24.32' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 25(12Q24.32) MUTATED 42 18.1 (22.3)
DEL PEAK 25(12Q24.32) WILD-TYPE 437 10.1 (9.8)

Figure S427.  Get High-res Image Gene #53: 'del_12q24.32' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_13q14.13' versus 'YEARS_TO_BIRTH'

P value = 0.0107 (Wilcoxon-test), Q value = 0.032

Table S428.  Gene #54: 'del_13q14.13' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 26(13Q14.13) MUTATED 217 61.6 (6.6)
DEL PEAK 26(13Q14.13) WILD-TYPE 254 60.3 (6.9)

Figure S428.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_13q14.13' versus 'PATHOLOGY_T_STAGE'

P value = 0.00535 (Fisher's exact test), Q value = 0.018

Table S429.  Gene #54: 'del_13q14.13' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 26(13Q14.13) MUTATED 70 145 6
DEL PEAK 26(13Q14.13) WILD-TYPE 118 136 4

Figure S429.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_13q14.13' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00192 (Fisher's exact test), Q value = 0.0078

Table S430.  Gene #54: 'del_13q14.13' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 26(13Q14.13) MUTATED 124 79 1 9
DEL PEAK 26(13Q14.13) WILD-TYPE 186 59 4 6

Figure S430.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_13q14.13' versus 'GLEASON_SCORE_COMBINED'

P value = 3.77e-05 (Wilcoxon-test), Q value = 0.00036

Table S431.  Gene #54: 'del_13q14.13' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 26(13Q14.13) MUTATED 221 7.7 (1.0)
DEL PEAK 26(13Q14.13) WILD-TYPE 261 7.4 (1.0)

Figure S431.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_13q14.13' versus 'GLEASON_SCORE_PRIMARY'

P value = 7.16e-05 (Wilcoxon-test), Q value = 0.00061

Table S432.  Gene #54: 'del_13q14.13' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 26(13Q14.13) MUTATED 221 3.8 (0.7)
DEL PEAK 26(13Q14.13) WILD-TYPE 261 3.6 (0.6)

Figure S432.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_13q14.13' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0837 (Wilcoxon-test), Q value = 0.16

Table S433.  Gene #54: 'del_13q14.13' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 26(13Q14.13) MUTATED 221 3.9 (0.7)
DEL PEAK 26(13Q14.13) WILD-TYPE 261 3.8 (0.7)

Figure S433.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_13q14.13' versus 'GLEASON_SCORE'

P value = 3.58e-05 (Wilcoxon-test), Q value = 0.00035

Table S434.  Gene #54: 'del_13q14.13' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 26(13Q14.13) MUTATED 221 7.8 (1.0)
DEL PEAK 26(13Q14.13) WILD-TYPE 261 7.4 (1.0)

Figure S434.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_13q14.13' versus 'PSA_RESULT_PREOP'

P value = 0.00775 (Wilcoxon-test), Q value = 0.024

Table S435.  Gene #54: 'del_13q14.13' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 26(13Q14.13) MUTATED 219 11.8 (12.6)
DEL PEAK 26(13Q14.13) WILD-TYPE 260 9.9 (10.7)

Figure S435.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_13q14.13' versus 'RACE'

P value = 0.00396 (Fisher's exact test), Q value = 0.014

Table S436.  Gene #54: 'del_13q14.13' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
DEL PEAK 26(13Q14.13) MUTATED 1 7 64
DEL PEAK 26(13Q14.13) WILD-TYPE 1 0 82

Figure S436.  Get High-res Image Gene #54: 'del_13q14.13' versus Clinical Feature #14: 'RACE'

'del_13q22.1' versus 'Time to Death'

P value = 0.109 (logrank test), Q value = 0.2

Table S437.  Gene #55: 'del_13q22.1' versus Clinical Feature #1: 'Time to Death'

nPatients nDeath Duration Range (Median), Month
ALL 481 8 0.7 - 165.2 (26.7)
DEL PEAK 27(13Q22.1) MUTATED 168 1 0.8 - 115.9 (30.4)
DEL PEAK 27(13Q22.1) WILD-TYPE 313 7 0.7 - 165.2 (25.4)

Figure S437.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #1: 'Time to Death'

'del_13q22.1' versus 'YEARS_TO_BIRTH'

P value = 0.00109 (Wilcoxon-test), Q value = 0.0052

Table S438.  Gene #55: 'del_13q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 27(13Q22.1) MUTATED 166 62.2 (6.7)
DEL PEAK 27(13Q22.1) WILD-TYPE 305 60.2 (6.7)

Figure S438.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_13q22.1' versus 'PATHOLOGY_T_STAGE'

P value = 0.00019 (Fisher's exact test), Q value = 0.0014

Table S439.  Gene #55: 'del_13q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 27(13Q22.1) MUTATED 50 111 8
DEL PEAK 27(13Q22.1) WILD-TYPE 138 170 2

Figure S439.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_13q22.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.02 (Fisher's exact test), Q value = 0.054

Table S440.  Gene #55: 'del_13q22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 27(13Q22.1) MUTATED 94 61 1 7
DEL PEAK 27(13Q22.1) WILD-TYPE 216 77 4 8

Figure S440.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_13q22.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0514 (Wilcoxon-test), Q value = 0.11

Table S441.  Gene #55: 'del_13q22.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 27(13Q22.1) MUTATED 146 0.6 (1.6)
DEL PEAK 27(13Q22.1) WILD-TYPE 249 0.3 (1.2)

Figure S441.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_13q22.1' versus 'GLEASON_SCORE_COMBINED'

P value = 1.52e-07 (Wilcoxon-test), Q value = 3.7e-06

Table S442.  Gene #55: 'del_13q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 27(13Q22.1) MUTATED 169 7.9 (1.0)
DEL PEAK 27(13Q22.1) WILD-TYPE 313 7.4 (1.0)

Figure S442.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_13q22.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 4.39e-06 (Wilcoxon-test), Q value = 7.1e-05

Table S443.  Gene #55: 'del_13q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 27(13Q22.1) MUTATED 169 3.9 (0.7)
DEL PEAK 27(13Q22.1) WILD-TYPE 313 3.6 (0.6)

Figure S443.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_13q22.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0022 (Wilcoxon-test), Q value = 0.0087

Table S444.  Gene #55: 'del_13q22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 27(13Q22.1) MUTATED 169 4.0 (0.7)
DEL PEAK 27(13Q22.1) WILD-TYPE 313 3.8 (0.7)

Figure S444.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_13q22.1' versus 'GLEASON_SCORE'

P value = 2.27e-09 (Wilcoxon-test), Q value = 1.5e-07

Table S445.  Gene #55: 'del_13q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 27(13Q22.1) MUTATED 169 8.0 (1.0)
DEL PEAK 27(13Q22.1) WILD-TYPE 313 7.4 (1.0)

Figure S445.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_13q22.1' versus 'PSA_RESULT_PREOP'

P value = 0.0312 (Wilcoxon-test), Q value = 0.076

Table S446.  Gene #55: 'del_13q22.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 27(13Q22.1) MUTATED 167 11.8 (11.7)
DEL PEAK 27(13Q22.1) WILD-TYPE 312 10.2 (11.6)

Figure S446.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_13q22.1' versus 'RACE'

P value = 0.00045 (Fisher's exact test), Q value = 0.0027

Table S447.  Gene #55: 'del_13q22.1' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
DEL PEAK 27(13Q22.1) MUTATED 0 7 51
DEL PEAK 27(13Q22.1) WILD-TYPE 2 0 95

Figure S447.  Get High-res Image Gene #55: 'del_13q22.1' versus Clinical Feature #14: 'RACE'

'del_15q21.3' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S448.  Gene #56: 'del_15q21.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 28(15Q21.3) MUTATED 9 53 4
DEL PEAK 28(15Q21.3) WILD-TYPE 179 228 6

Figure S448.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_15q21.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.0014 (Fisher's exact test), Q value = 0.0065

Table S449.  Gene #56: 'del_15q21.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 28(15Q21.3) MUTATED 38 20
DEL PEAK 28(15Q21.3) WILD-TYPE 300 55

Figure S449.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_15q21.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000522 (Wilcoxon-test), Q value = 0.0029

Table S450.  Gene #56: 'del_15q21.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 28(15Q21.3) MUTATED 57 0.8 (1.4)
DEL PEAK 28(15Q21.3) WILD-TYPE 338 0.4 (1.4)

Figure S450.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_15q21.3' versus 'GLEASON_SCORE_COMBINED'

P value = 2.29e-08 (Wilcoxon-test), Q value = 7.2e-07

Table S451.  Gene #56: 'del_15q21.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 28(15Q21.3) MUTATED 66 8.2 (1.1)
DEL PEAK 28(15Q21.3) WILD-TYPE 416 7.4 (1.0)

Figure S451.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_15q21.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 4.67e-07 (Wilcoxon-test), Q value = 9.9e-06

Table S452.  Gene #56: 'del_15q21.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 28(15Q21.3) MUTATED 66 4.1 (0.7)
DEL PEAK 28(15Q21.3) WILD-TYPE 416 3.6 (0.7)

Figure S452.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_15q21.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00073 (Wilcoxon-test), Q value = 0.0038

Table S453.  Gene #56: 'del_15q21.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 28(15Q21.3) MUTATED 66 4.1 (0.7)
DEL PEAK 28(15Q21.3) WILD-TYPE 416 3.8 (0.7)

Figure S453.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_15q21.3' versus 'GLEASON_SCORE'

P value = 5.67e-09 (Wilcoxon-test), Q value = 2.9e-07

Table S454.  Gene #56: 'del_15q21.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 28(15Q21.3) MUTATED 66 8.3 (1.0)
DEL PEAK 28(15Q21.3) WILD-TYPE 416 7.5 (1.0)

Figure S454.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_15q21.3' versus 'PSA_VALUE'

P value = 0.121 (Wilcoxon-test), Q value = 0.22

Table S455.  Gene #56: 'del_15q21.3' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 28(15Q21.3) MUTATED 52 2.0 (5.9)
DEL PEAK 28(15Q21.3) WILD-TYPE 374 1.0 (3.8)

Figure S455.  Get High-res Image Gene #56: 'del_15q21.3' versus Clinical Feature #13: 'PSA_VALUE'

'del_16q22.3' versus 'YEARS_TO_BIRTH'

P value = 0.0627 (Wilcoxon-test), Q value = 0.13

Table S456.  Gene #57: 'del_16q22.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 29(16Q22.3) MUTATED 181 61.6 (6.6)
DEL PEAK 29(16Q22.3) WILD-TYPE 290 60.4 (6.9)

Figure S456.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_16q22.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.00035 (Fisher's exact test), Q value = 0.0022

Table S457.  Gene #57: 'del_16q22.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 29(16Q22.3) MUTATED 53 126 6
DEL PEAK 29(16Q22.3) WILD-TYPE 135 155 4

Figure S457.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_16q22.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.0273 (Fisher's exact test), Q value = 0.068

Table S458.  Gene #57: 'del_16q22.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 29(16Q22.3) MUTATED 128 39
DEL PEAK 29(16Q22.3) WILD-TYPE 210 36

Figure S458.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_16q22.3' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0702 (Fisher's exact test), Q value = 0.15

Table S459.  Gene #57: 'del_16q22.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 29(16Q22.3) MUTATED 108 65 1 5
DEL PEAK 29(16Q22.3) WILD-TYPE 202 73 4 10

Figure S459.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_16q22.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0104 (Wilcoxon-test), Q value = 0.032

Table S460.  Gene #57: 'del_16q22.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 29(16Q22.3) MUTATED 158 0.6 (1.7)
DEL PEAK 29(16Q22.3) WILD-TYPE 237 0.3 (1.1)

Figure S460.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_16q22.3' versus 'GLEASON_SCORE_COMBINED'

P value = 1.34e-08 (Wilcoxon-test), Q value = 5.5e-07

Table S461.  Gene #57: 'del_16q22.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 29(16Q22.3) MUTATED 185 7.9 (1.0)
DEL PEAK 29(16Q22.3) WILD-TYPE 297 7.3 (1.0)

Figure S461.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_16q22.3' versus 'GLEASON_SCORE_PRIMARY'

P value = 1.55e-07 (Wilcoxon-test), Q value = 3.7e-06

Table S462.  Gene #57: 'del_16q22.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 29(16Q22.3) MUTATED 185 3.9 (0.7)
DEL PEAK 29(16Q22.3) WILD-TYPE 297 3.6 (0.6)

Figure S462.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_16q22.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00139 (Wilcoxon-test), Q value = 0.0064

Table S463.  Gene #57: 'del_16q22.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 29(16Q22.3) MUTATED 185 4.0 (0.7)
DEL PEAK 29(16Q22.3) WILD-TYPE 297 3.8 (0.6)

Figure S463.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_16q22.3' versus 'GLEASON_SCORE'

P value = 5.69e-09 (Wilcoxon-test), Q value = 2.9e-07

Table S464.  Gene #57: 'del_16q22.3' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 29(16Q22.3) MUTATED 185 7.9 (1.0)
DEL PEAK 29(16Q22.3) WILD-TYPE 297 7.4 (0.9)

Figure S464.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_16q22.3' versus 'PSA_RESULT_PREOP'

P value = 0.00202 (Wilcoxon-test), Q value = 0.0081

Table S465.  Gene #57: 'del_16q22.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 29(16Q22.3) MUTATED 185 11.7 (10.8)
DEL PEAK 29(16Q22.3) WILD-TYPE 294 10.2 (12.1)

Figure S465.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_16q22.3' versus 'PSA_VALUE'

P value = 0.0877 (Wilcoxon-test), Q value = 0.17

Table S466.  Gene #57: 'del_16q22.3' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 29(16Q22.3) MUTATED 159 1.5 (4.9)
DEL PEAK 29(16Q22.3) WILD-TYPE 267 0.8 (3.6)

Figure S466.  Get High-res Image Gene #57: 'del_16q22.3' versus Clinical Feature #13: 'PSA_VALUE'

'del_16q24.1' versus 'PATHOLOGY_T_STAGE'

P value = 1e-05 (Fisher's exact test), Q value = 0.00012

Table S467.  Gene #58: 'del_16q24.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 30(16Q24.1) MUTATED 56 144 6
DEL PEAK 30(16Q24.1) WILD-TYPE 132 137 4

Figure S467.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_16q24.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.0402 (Fisher's exact test), Q value = 0.092

Table S468.  Gene #58: 'del_16q24.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 30(16Q24.1) MUTATED 144 42
DEL PEAK 30(16Q24.1) WILD-TYPE 194 33

Figure S468.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_16q24.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0203 (Wilcoxon-test), Q value = 0.055

Table S469.  Gene #58: 'del_16q24.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 30(16Q24.1) MUTATED 178 0.6 (1.8)
DEL PEAK 30(16Q24.1) WILD-TYPE 217 0.3 (0.8)

Figure S469.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_16q24.1' versus 'GLEASON_SCORE_COMBINED'

P value = 6.08e-09 (Wilcoxon-test), Q value = 2.9e-07

Table S470.  Gene #58: 'del_16q24.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 30(16Q24.1) MUTATED 206 7.9 (1.0)
DEL PEAK 30(16Q24.1) WILD-TYPE 276 7.3 (1.0)

Figure S470.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_16q24.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 3.39e-09 (Wilcoxon-test), Q value = 2.1e-07

Table S471.  Gene #58: 'del_16q24.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 30(16Q24.1) MUTATED 206 3.9 (0.7)
DEL PEAK 30(16Q24.1) WILD-TYPE 276 3.5 (0.6)

Figure S471.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_16q24.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.01 (Wilcoxon-test), Q value = 0.031

Table S472.  Gene #58: 'del_16q24.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 30(16Q24.1) MUTATED 206 4.0 (0.7)
DEL PEAK 30(16Q24.1) WILD-TYPE 276 3.8 (0.6)

Figure S472.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_16q24.1' versus 'GLEASON_SCORE'

P value = 5.24e-09 (Wilcoxon-test), Q value = 2.9e-07

Table S473.  Gene #58: 'del_16q24.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 30(16Q24.1) MUTATED 206 7.9 (1.0)
DEL PEAK 30(16Q24.1) WILD-TYPE 276 7.4 (0.9)

Figure S473.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_16q24.1' versus 'PSA_RESULT_PREOP'

P value = 0.000573 (Wilcoxon-test), Q value = 0.0031

Table S474.  Gene #58: 'del_16q24.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

nPatients Mean (Std.Dev)
ALL 479 10.8 (11.7)
DEL PEAK 30(16Q24.1) MUTATED 206 11.9 (10.7)
DEL PEAK 30(16Q24.1) WILD-TYPE 273 10.0 (12.3)

Figure S474.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #12: 'PSA_RESULT_PREOP'

'del_16q24.1' versus 'PSA_VALUE'

P value = 0.09 (Wilcoxon-test), Q value = 0.17

Table S475.  Gene #58: 'del_16q24.1' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 30(16Q24.1) MUTATED 179 1.7 (5.2)
DEL PEAK 30(16Q24.1) WILD-TYPE 247 0.6 (3.0)

Figure S475.  Get High-res Image Gene #58: 'del_16q24.1' versus Clinical Feature #13: 'PSA_VALUE'

'del_17p13.1' versus 'PATHOLOGY_T_STAGE'

P value = 3e-05 (Fisher's exact test), Q value = 3e-04

Table S476.  Gene #59: 'del_17p13.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 31(17P13.1) MUTATED 39 109 6
DEL PEAK 31(17P13.1) WILD-TYPE 149 172 4

Figure S476.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_17p13.1' versus 'PATHOLOGY_N_STAGE'

P value = 0.00668 (Fisher's exact test), Q value = 0.022

Table S477.  Gene #59: 'del_17p13.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 31(17P13.1) MUTATED 104 36
DEL PEAK 31(17P13.1) WILD-TYPE 234 39

Figure S477.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_17p13.1' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0448 (Fisher's exact test), Q value = 0.1

Table S478.  Gene #59: 'del_17p13.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 31(17P13.1) MUTATED 91 56 0 4
DEL PEAK 31(17P13.1) WILD-TYPE 219 82 5 11

Figure S478.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_17p13.1' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.000689 (Wilcoxon-test), Q value = 0.0036

Table S479.  Gene #59: 'del_17p13.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 31(17P13.1) MUTATED 130 0.7 (1.7)
DEL PEAK 31(17P13.1) WILD-TYPE 265 0.3 (1.2)

Figure S479.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_17p13.1' versus 'GLEASON_SCORE_COMBINED'

P value = 8.2e-09 (Wilcoxon-test), Q value = 3.6e-07

Table S480.  Gene #59: 'del_17p13.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 31(17P13.1) MUTATED 154 8.0 (1.0)
DEL PEAK 31(17P13.1) WILD-TYPE 328 7.4 (0.9)

Figure S480.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_17p13.1' versus 'GLEASON_SCORE_PRIMARY'

P value = 6.94e-07 (Wilcoxon-test), Q value = 1.3e-05

Table S481.  Gene #59: 'del_17p13.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 31(17P13.1) MUTATED 154 3.9 (0.7)
DEL PEAK 31(17P13.1) WILD-TYPE 328 3.6 (0.7)

Figure S481.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_17p13.1' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.000207 (Wilcoxon-test), Q value = 0.0015

Table S482.  Gene #59: 'del_17p13.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 31(17P13.1) MUTATED 154 4.0 (0.7)
DEL PEAK 31(17P13.1) WILD-TYPE 328 3.8 (0.6)

Figure S482.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_17p13.1' versus 'GLEASON_SCORE'

P value = 2.41e-08 (Wilcoxon-test), Q value = 7.3e-07

Table S483.  Gene #59: 'del_17p13.1' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 31(17P13.1) MUTATED 154 8.0 (1.0)
DEL PEAK 31(17P13.1) WILD-TYPE 328 7.4 (0.9)

Figure S483.  Get High-res Image Gene #59: 'del_17p13.1' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_17q21.31' versus 'PATHOLOGY_T_STAGE'

P value = 0.125 (Fisher's exact test), Q value = 0.23

Table S484.  Gene #60: 'del_17q21.31' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 32(17Q21.31) MUTATED 29 61 3
DEL PEAK 32(17Q21.31) WILD-TYPE 159 220 7

Figure S484.  Get High-res Image Gene #60: 'del_17q21.31' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_18q21.31' versus 'PATHOLOGY_T_STAGE'

P value = 6e-04 (Fisher's exact test), Q value = 0.0032

Table S485.  Gene #61: 'del_18q21.31' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 33(18Q21.31) MUTATED 32 90 4
DEL PEAK 33(18Q21.31) WILD-TYPE 156 191 6

Figure S485.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_18q21.31' versus 'PATHOLOGY_N_STAGE'

P value = 0.0222 (Fisher's exact test), Q value = 0.058

Table S486.  Gene #61: 'del_18q21.31' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 33(18Q21.31) MUTATED 85 29
DEL PEAK 33(18Q21.31) WILD-TYPE 253 46

Figure S486.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_18q21.31' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0013 (Fisher's exact test), Q value = 0.0061

Table S487.  Gene #61: 'del_18q21.31' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 33(18Q21.31) MUTATED 69 53 0 2
DEL PEAK 33(18Q21.31) WILD-TYPE 241 85 5 13

Figure S487.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_18q21.31' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0146 (Wilcoxon-test), Q value = 0.042

Table S488.  Gene #61: 'del_18q21.31' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 33(18Q21.31) MUTATED 109 0.7 (2.1)
DEL PEAK 33(18Q21.31) WILD-TYPE 286 0.3 (1.0)

Figure S488.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_18q21.31' versus 'GLEASON_SCORE_COMBINED'

P value = 7.2e-05 (Wilcoxon-test), Q value = 0.00061

Table S489.  Gene #61: 'del_18q21.31' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 33(18Q21.31) MUTATED 126 7.9 (1.0)
DEL PEAK 33(18Q21.31) WILD-TYPE 356 7.4 (1.0)

Figure S489.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_18q21.31' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.00169 (Wilcoxon-test), Q value = 0.0073

Table S490.  Gene #61: 'del_18q21.31' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 33(18Q21.31) MUTATED 126 3.8 (0.7)
DEL PEAK 33(18Q21.31) WILD-TYPE 356 3.6 (0.7)

Figure S490.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_18q21.31' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00393 (Wilcoxon-test), Q value = 0.014

Table S491.  Gene #61: 'del_18q21.31' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 33(18Q21.31) MUTATED 126 4.0 (0.7)
DEL PEAK 33(18Q21.31) WILD-TYPE 356 3.8 (0.7)

Figure S491.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_18q21.31' versus 'GLEASON_SCORE'

P value = 1.26e-05 (Wilcoxon-test), Q value = 0.00014

Table S492.  Gene #61: 'del_18q21.31' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 33(18Q21.31) MUTATED 126 7.9 (1.0)
DEL PEAK 33(18Q21.31) WILD-TYPE 356 7.5 (1.0)

Figure S492.  Get High-res Image Gene #61: 'del_18q21.31' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_18q23' versus 'YEARS_TO_BIRTH'

P value = 0.108 (Wilcoxon-test), Q value = 0.2

Table S493.  Gene #62: 'del_18q23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 34(18Q23) MUTATED 131 61.6 (6.5)
DEL PEAK 34(18Q23) WILD-TYPE 340 60.6 (6.9)

Figure S493.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_18q23' versus 'PATHOLOGY_T_STAGE'

P value = 0.00047 (Fisher's exact test), Q value = 0.0027

Table S494.  Gene #62: 'del_18q23' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 34(18Q23) MUTATED 34 94 4
DEL PEAK 34(18Q23) WILD-TYPE 154 187 6

Figure S494.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_18q23' versus 'PATHOLOGY_N_STAGE'

P value = 0.00469 (Fisher's exact test), Q value = 0.016

Table S495.  Gene #62: 'del_18q23' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 34(18Q23) MUTATED 87 32
DEL PEAK 34(18Q23) WILD-TYPE 251 43

Figure S495.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_18q23' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.00441 (Fisher's exact test), Q value = 0.015

Table S496.  Gene #62: 'del_18q23' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 34(18Q23) MUTATED 74 53 0 2
DEL PEAK 34(18Q23) WILD-TYPE 236 85 5 13

Figure S496.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_18q23' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.00235 (Wilcoxon-test), Q value = 0.0092

Table S497.  Gene #62: 'del_18q23' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 34(18Q23) MUTATED 114 0.8 (2.1)
DEL PEAK 34(18Q23) WILD-TYPE 281 0.3 (0.9)

Figure S497.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_18q23' versus 'GLEASON_SCORE_COMBINED'

P value = 2.53e-05 (Wilcoxon-test), Q value = 0.00026

Table S498.  Gene #62: 'del_18q23' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 34(18Q23) MUTATED 132 7.9 (1.0)
DEL PEAK 34(18Q23) WILD-TYPE 350 7.4 (1.0)

Figure S498.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_18q23' versus 'GLEASON_SCORE_PRIMARY'

P value = 0.000573 (Wilcoxon-test), Q value = 0.0031

Table S499.  Gene #62: 'del_18q23' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 34(18Q23) MUTATED 132 3.9 (0.7)
DEL PEAK 34(18Q23) WILD-TYPE 350 3.6 (0.7)

Figure S499.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_18q23' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.00322 (Wilcoxon-test), Q value = 0.012

Table S500.  Gene #62: 'del_18q23' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 34(18Q23) MUTATED 132 4.0 (0.7)
DEL PEAK 34(18Q23) WILD-TYPE 350 3.8 (0.7)

Figure S500.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_18q23' versus 'GLEASON_SCORE'

P value = 2.51e-06 (Wilcoxon-test), Q value = 4.3e-05

Table S501.  Gene #62: 'del_18q23' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 34(18Q23) MUTATED 132 7.9 (1.0)
DEL PEAK 34(18Q23) WILD-TYPE 350 7.5 (1.0)

Figure S501.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_18q23' versus 'PSA_VALUE'

P value = 0.0533 (Wilcoxon-test), Q value = 0.12

Table S502.  Gene #62: 'del_18q23' versus Clinical Feature #13: 'PSA_VALUE'

nPatients Mean (Std.Dev)
ALL 426 1.1 (4.1)
DEL PEAK 34(18Q23) MUTATED 115 1.7 (5.6)
DEL PEAK 34(18Q23) WILD-TYPE 311 0.9 (3.4)

Figure S502.  Get High-res Image Gene #62: 'del_18q23' versus Clinical Feature #13: 'PSA_VALUE'

'del_19q13.2' versus 'YEARS_TO_BIRTH'

P value = 0.0343 (Wilcoxon-test), Q value = 0.082

Table S503.  Gene #63: 'del_19q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

nPatients Mean (Std.Dev)
ALL 471 60.9 (6.8)
DEL PEAK 35(19Q13.2) MUTATED 48 62.7 (6.7)
DEL PEAK 35(19Q13.2) WILD-TYPE 423 60.7 (6.8)

Figure S503.  Get High-res Image Gene #63: 'del_19q13.2' versus Clinical Feature #2: 'YEARS_TO_BIRTH'

'del_19q13.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.0063 (Fisher's exact test), Q value = 0.02

Table S504.  Gene #63: 'del_19q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 35(19Q13.2) MUTATED 11 35 3
DEL PEAK 35(19Q13.2) WILD-TYPE 177 246 7

Figure S504.  Get High-res Image Gene #63: 'del_19q13.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_19q13.2' versus 'COMPLETENESS_OF_RESECTION'

P value = 0.0721 (Fisher's exact test), Q value = 0.15

Table S505.  Gene #63: 'del_19q13.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

nPatients R0 R1 R2 RX
ALL 310 138 5 15
DEL PEAK 35(19Q13.2) MUTATED 27 22 0 0
DEL PEAK 35(19Q13.2) WILD-TYPE 283 116 5 15

Figure S505.  Get High-res Image Gene #63: 'del_19q13.2' versus Clinical Feature #6: 'COMPLETENESS_OF_RESECTION'

'del_19q13.2' versus 'GLEASON_SCORE_COMBINED'

P value = 0.000335 (Wilcoxon-test), Q value = 0.0022

Table S506.  Gene #63: 'del_19q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 35(19Q13.2) MUTATED 49 8.1 (1.1)
DEL PEAK 35(19Q13.2) WILD-TYPE 433 7.5 (1.0)

Figure S506.  Get High-res Image Gene #63: 'del_19q13.2' versus Clinical Feature #8: 'GLEASON_SCORE_COMBINED'

'del_19q13.2' versus 'GLEASON_SCORE_PRIMARY'

P value = 4.38e-05 (Wilcoxon-test), Q value = 0.00041

Table S507.  Gene #63: 'del_19q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

nPatients Mean (Std.Dev)
ALL 482 3.7 (0.7)
DEL PEAK 35(19Q13.2) MUTATED 49 4.1 (0.7)
DEL PEAK 35(19Q13.2) WILD-TYPE 433 3.6 (0.7)

Figure S507.  Get High-res Image Gene #63: 'del_19q13.2' versus Clinical Feature #9: 'GLEASON_SCORE_PRIMARY'

'del_19q13.2' versus 'GLEASON_SCORE'

P value = 0.00123 (Wilcoxon-test), Q value = 0.0058

Table S508.  Gene #63: 'del_19q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 35(19Q13.2) MUTATED 49 8.0 (1.0)
DEL PEAK 35(19Q13.2) WILD-TYPE 433 7.5 (1.0)

Figure S508.  Get High-res Image Gene #63: 'del_19q13.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_21q22.2' versus 'PATHOLOGY_T_STAGE'

P value = 0.0023 (Fisher's exact test), Q value = 0.0091

Table S509.  Gene #64: 'del_21q22.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 36(21Q22.2) MUTATED 10 37 3
DEL PEAK 36(21Q22.2) WILD-TYPE 178 244 7

Figure S509.  Get High-res Image Gene #64: 'del_21q22.2' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_21q22.2' versus 'PATHOLOGY_N_STAGE'

P value = 0.101 (Fisher's exact test), Q value = 0.19

Table S510.  Gene #64: 'del_21q22.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 36(21Q22.2) MUTATED 32 12
DEL PEAK 36(21Q22.2) WILD-TYPE 306 63

Figure S510.  Get High-res Image Gene #64: 'del_21q22.2' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_21q22.2' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.061 (Wilcoxon-test), Q value = 0.13

Table S511.  Gene #64: 'del_21q22.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 36(21Q22.2) MUTATED 41 0.8 (1.9)
DEL PEAK 36(21Q22.2) WILD-TYPE 354 0.4 (1.3)

Figure S511.  Get High-res Image Gene #64: 'del_21q22.2' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_21q22.2' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.064 (Wilcoxon-test), Q value = 0.14

Table S512.  Gene #64: 'del_21q22.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 36(21Q22.2) MUTATED 50 4.0 (0.7)
DEL PEAK 36(21Q22.2) WILD-TYPE 432 3.8 (0.7)

Figure S512.  Get High-res Image Gene #64: 'del_21q22.2' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_21q22.2' versus 'GLEASON_SCORE'

P value = 0.0575 (Wilcoxon-test), Q value = 0.12

Table S513.  Gene #64: 'del_21q22.2' versus Clinical Feature #11: 'GLEASON_SCORE'

nPatients Mean (Std.Dev)
ALL 482 7.6 (1.0)
DEL PEAK 36(21Q22.2) MUTATED 50 7.8 (1.1)
DEL PEAK 36(21Q22.2) WILD-TYPE 432 7.6 (1.0)

Figure S513.  Get High-res Image Gene #64: 'del_21q22.2' versus Clinical Feature #11: 'GLEASON_SCORE'

'del_21q22.2' versus 'RACE'

P value = 0.0773 (Fisher's exact test), Q value = 0.16

Table S514.  Gene #64: 'del_21q22.2' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
DEL PEAK 36(21Q22.2) MUTATED 1 2 15
DEL PEAK 36(21Q22.2) WILD-TYPE 1 5 131

Figure S514.  Get High-res Image Gene #64: 'del_21q22.2' versus Clinical Feature #14: 'RACE'

'del_21q22.3' versus 'PATHOLOGY_T_STAGE'

P value = 0.0437 (Fisher's exact test), Q value = 0.1

Table S515.  Gene #65: 'del_21q22.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

nPatients T2 T3 T4
ALL 188 281 10
DEL PEAK 37(21Q22.3) MUTATED 46 93 5
DEL PEAK 37(21Q22.3) WILD-TYPE 142 188 5

Figure S515.  Get High-res Image Gene #65: 'del_21q22.3' versus Clinical Feature #3: 'PATHOLOGY_T_STAGE'

'del_21q22.3' versus 'PATHOLOGY_N_STAGE'

P value = 0.128 (Fisher's exact test), Q value = 0.23

Table S516.  Gene #65: 'del_21q22.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

nPatients 0 1
ALL 338 75
DEL PEAK 37(21Q22.3) MUTATED 98 29
DEL PEAK 37(21Q22.3) WILD-TYPE 240 46

Figure S516.  Get High-res Image Gene #65: 'del_21q22.3' versus Clinical Feature #4: 'PATHOLOGY_N_STAGE'

'del_21q22.3' versus 'NUMBER_OF_LYMPH_NODES'

P value = 0.0491 (Wilcoxon-test), Q value = 0.11

Table S517.  Gene #65: 'del_21q22.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

nPatients Mean (Std.Dev)
ALL 395 0.4 (1.4)
DEL PEAK 37(21Q22.3) MUTATED 119 0.7 (2.0)
DEL PEAK 37(21Q22.3) WILD-TYPE 276 0.3 (1.0)

Figure S517.  Get High-res Image Gene #65: 'del_21q22.3' versus Clinical Feature #7: 'NUMBER_OF_LYMPH_NODES'

'del_21q22.3' versus 'GLEASON_SCORE_SECONDARY'

P value = 0.0872 (Wilcoxon-test), Q value = 0.17

Table S518.  Gene #65: 'del_21q22.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

nPatients Mean (Std.Dev)
ALL 482 3.9 (0.7)
DEL PEAK 37(21Q22.3) MUTATED 145 4.0 (0.7)
DEL PEAK 37(21Q22.3) WILD-TYPE 337 3.8 (0.7)

Figure S518.  Get High-res Image Gene #65: 'del_21q22.3' versus Clinical Feature #10: 'GLEASON_SCORE_SECONDARY'

'del_21q22.3' versus 'RACE'

P value = 0.131 (Fisher's exact test), Q value = 0.23

Table S519.  Gene #65: 'del_21q22.3' versus Clinical Feature #14: 'RACE'

nPatients ASIAN BLACK OR AFRICAN AMERICAN WHITE
ALL 2 7 146
DEL PEAK 37(21Q22.3) MUTATED 2 1 50
DEL PEAK 37(21Q22.3) WILD-TYPE 0 6 96

Figure S519.  Get High-res Image Gene #65: 'del_21q22.3' versus Clinical Feature #14: 'RACE'

Methods & Data
Input

  • Copy number data file = all_lesions.txt from GISTIC pipeline

  • Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/PRAD-TP/15098590/transformed.cor.cli.txt

  • Clinical data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/Append_Data/PRAD-TP/15087329/PRAD-TP.merged_data.txt

  • Number of patients = 482

  • Number of significantly focal cnvs = 65

  • Number of selected clinical features = 14

  • Exclude genes that fewer than K tumors have mutations, K = 3

Survival analysis

For survival clinical features, the Kaplan-Meier survival curves of tumors with and without gene mutations were plotted and the statistical significance P values were estimated by logrank test (Bland and Altman 2004) using the 'survdiff' function in R

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References
[1] Bland and Altman, Statistics notes: The logrank test, BMJ 328(7447):1073 (2004)
[2] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)
[3] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)
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