This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 74 arm-level events and 10 molecular subtypes across 150 patients, 373 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q gain cnv correlated to 'MIRSEQ_CNMF'.
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2p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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2q gain cnv correlated to 'METHLYATION_CNMF'.
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3p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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5p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'RPPA_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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12q gain cnv correlated to 'MIRSEQ_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16q gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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17p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
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20q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'RPPA_CNMF'.
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22q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xq gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1p loss cnv correlated to 'MIRSEQ_CNMF'.
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3p loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q loss cnv correlated to 'MIRSEQ_MATURE_CNMF'.
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4p loss cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CNMF'.
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4q loss cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q loss cnv correlated to 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p loss cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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6q loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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8p loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p loss cnv correlated to 'CN_CNMF'.
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9q loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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13q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p loss cnv correlated to 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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16q loss cnv correlated to 'MIRSEQ_CNMF'.
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17p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p loss cnv correlated to 'MRNASEQ_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
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18q loss cnv correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p loss cnv correlated to 'MIRSEQ_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 74 arm-level events and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 373 significant findings detected.
|
Clinical Features |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 1p gain | 37 (25%) | 113 |
0.00245 (0.0104) |
0.00045 (0.00271) |
0.00289 (0.0118) |
0.0148 (0.0385) |
0.00044 (0.00269) |
0.00248 (0.0105) |
0.0001 (0.000813) |
0.00017 (0.00126) |
1e-05 (0.000128) |
0.00066 (0.00376) |
| 8q gain | 111 (74%) | 39 |
0.0208 (0.0499) |
0.00331 (0.0128) |
0.00457 (0.0161) |
0.00361 (0.0137) |
9e-05 (0.000748) |
0.00034 (0.00227) |
0.00013 (0.00101) |
0.00011 (0.000885) |
0.00031 (0.0021) |
0.00022 (0.00157) |
| 17p gain | 40 (27%) | 110 |
1e-05 (0.000128) |
2e-05 (0.000211) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
| 17q gain | 51 (34%) | 99 |
0.00016 (0.00122) |
5e-05 (0.000451) |
4e-05 (0.000375) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
| 19p gain | 36 (24%) | 114 |
0.0105 (0.0305) |
0.00015 (0.00116) |
0.00264 (0.0109) |
0.00206 (0.00928) |
9e-05 (0.000748) |
0.00085 (0.00466) |
0.0435 (0.0889) |
8e-05 (0.000688) |
0.00051 (0.00302) |
4e-05 (0.000375) |
| xp gain | 22 (15%) | 128 |
0.0004 (0.00255) |
0.0194 (0.0475) |
0.0316 (0.0695) |
0.013 (0.0349) |
0.00058 (0.00338) |
0.00303 (0.012) |
0.0008 (0.00442) |
0.00021 (0.00152) |
0.00174 (0.0082) |
0.00399 (0.0146) |
| xq gain | 22 (15%) | 128 |
0.00189 (0.00874) |
0.0182 (0.0451) |
0.0431 (0.0886) |
0.0195 (0.0477) |
0.00075 (0.0042) |
0.00377 (0.0141) |
0.00257 (0.0107) |
0.00035 (0.00229) |
0.00139 (0.00695) |
0.00457 (0.0161) |
| 10p loss | 77 (51%) | 73 |
0.0215 (0.0511) |
0.00044 (0.00269) |
0.00603 (0.0202) |
0.0129 (0.0349) |
0.00026 (0.0018) |
0.00553 (0.0189) |
0.0378 (0.0792) |
0.00088 (0.00479) |
0.00222 (0.00978) |
0.0013 (0.00654) |
| 15q loss | 29 (19%) | 121 |
0.0058 (0.0196) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
| 19p loss | 50 (33%) | 100 |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
| 19q loss | 53 (35%) | 97 |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
1e-05 (0.000128) |
| 22q loss | 45 (30%) | 105 |
0.00239 (0.0102) |
1e-05 (0.000128) |
0.00017 (0.00126) |
2e-05 (0.000211) |
1e-05 (0.000128) |
1e-05 (0.000128) |
4e-05 (0.000375) |
1e-05 (0.000128) |
1e-05 (0.000128) |
2e-05 (0.000211) |
| 7p gain | 121 (81%) | 29 |
0.00453 (0.0161) |
0.0565 (0.108) |
0.0231 (0.0538) |
0.0203 (0.0491) |
0.004 (0.0146) |
0.00866 (0.0258) |
0.00818 (0.0249) |
0.00748 (0.0233) |
0.00688 (0.0222) |
0.0226 (0.0533) |
| 8p gain | 110 (73%) | 40 |
0.0648 (0.119) |
0.00618 (0.0204) |
0.00026 (0.0018) |
0.0003 (0.00206) |
4e-05 (0.000375) |
0.00019 (0.00139) |
9e-05 (0.000748) |
3e-05 (3e-04) |
6e-05 (0.000535) |
8e-05 (0.000688) |
| 15q gain | 51 (34%) | 99 |
0.0505 (0.0997) |
0.00207 (0.00928) |
0.00012 (0.000955) |
0.00079 (0.0044) |
1e-05 (0.000128) |
2e-05 (0.000211) |
8e-05 (0.000688) |
1e-05 (0.000128) |
4e-05 (0.000375) |
2e-05 (0.000211) |
| 19q gain | 29 (19%) | 121 |
0.0163 (0.0411) |
0.00013 (0.00101) |
0.00224 (0.00981) |
0.00191 (0.00878) |
2e-05 (0.000211) |
0.00063 (0.00364) |
0.146 (0.221) |
3e-05 (3e-04) |
0.00041 (0.00259) |
1e-05 (0.000128) |
| 22q gain | 38 (25%) | 112 |
2e-05 (0.000211) |
0.00121 (0.00631) |
0.00125 (0.00634) |
0.00032 (0.00215) |
3e-05 (3e-04) |
1e-05 (0.000128) |
0.0563 (0.107) |
2e-05 (0.000211) |
5e-05 (0.000451) |
1e-05 (0.000128) |
| 8p loss | 12 (8%) | 138 |
0.356 (0.444) |
0.0495 (0.0984) |
0.01 (0.0294) |
0.00732 (0.023) |
0.0108 (0.0308) |
0.0478 (0.0959) |
0.00805 (0.0246) |
0.00188 (0.00874) |
0.00708 (0.0226) |
0.0227 (0.0533) |
| 8q loss | 5 (3%) | 145 |
0.191 (0.274) |
0.0243 (0.0559) |
0.0239 (0.0552) |
0.0145 (0.0378) |
0.00233 (0.01) |
0.012 (0.0334) |
0.00124 (0.00633) |
0.0023 (0.01) |
0.00266 (0.0109) |
0.00346 (0.0133) |
| 17p loss | 37 (25%) | 113 |
2e-05 (0.000211) |
0.0397 (0.0827) |
0.0174 (0.0435) |
0.003 (0.0119) |
0.00436 (0.0158) |
0.00022 (0.00157) |
0.0586 (0.11) |
0.00361 (0.0137) |
0.00163 (0.00783) |
3e-05 (3e-04) |
| 3p gain | 27 (18%) | 123 |
0.0219 (0.0519) |
0.393 (0.476) |
0.00156 (0.00755) |
0.0161 (0.0408) |
0.00758 (0.0235) |
0.007 (0.0224) |
0.0841 (0.143) |
0.0126 (0.0343) |
0.0149 (0.0387) |
0.0111 (0.0315) |
| 5p gain | 6 (4%) | 144 |
0.674 (0.739) |
0.0263 (0.0594) |
0.00799 (0.0246) |
0.221 (0.305) |
0.0113 (0.0318) |
0.00803 (0.0246) |
0.00456 (0.0161) |
0.00659 (0.0215) |
0.004 (0.0146) |
0.00615 (0.0204) |
| 16p gain | 16 (11%) | 134 |
0.0121 (0.0335) |
0.0798 (0.137) |
0.0529 (0.104) |
0.00354 (0.0136) |
0.00379 (0.0141) |
0.0189 (0.0466) |
0.00219 (0.00976) |
0.00627 (0.0206) |
0.00262 (0.0109) |
0.0204 (0.0491) |
| 3p loss | 30 (20%) | 120 |
0.933 (0.956) |
0.0301 (0.0671) |
0.00297 (0.0119) |
0.319 (0.411) |
0.00145 (0.0072) |
0.00317 (0.0124) |
0.00108 (0.00575) |
0.00065 (0.00373) |
0.00293 (0.0118) |
0.00153 (0.0075) |
| 10q loss | 72 (48%) | 78 |
0.00888 (0.0264) |
2e-05 (0.000211) |
0.0846 (0.143) |
0.104 (0.171) |
0.00017 (0.00126) |
0.00222 (0.00978) |
0.032 (0.0696) |
0.00055 (0.00323) |
0.00154 (0.0075) |
0.00152 (0.0075) |
| 14q loss | 20 (13%) | 130 |
0.12 (0.19) |
0.00068 (0.00384) |
0.0299 (0.0669) |
0.118 (0.186) |
0.00448 (0.0161) |
2e-05 (0.000211) |
0.0302 (0.0671) |
0.0032 (0.0125) |
0.00288 (0.0118) |
0.0116 (0.0326) |
| 3q gain | 36 (24%) | 114 |
0.00688 (0.0222) |
0.177 (0.257) |
0.00511 (0.0177) |
0.00528 (0.0181) |
0.032 (0.0696) |
0.0323 (0.0699) |
0.0792 (0.137) |
0.0214 (0.0511) |
0.0391 (0.0817) |
0.0764 (0.134) |
| 6p gain | 28 (19%) | 122 |
0.00042 (0.00263) |
0.754 (0.802) |
0.319 (0.411) |
0.0376 (0.0792) |
0.013 (0.0349) |
0.00096 (0.00515) |
0.0179 (0.0444) |
0.00648 (0.0212) |
0.0549 (0.105) |
0.0197 (0.0479) |
| 6q gain | 23 (15%) | 127 |
0.0223 (0.0527) |
0.883 (0.914) |
0.613 (0.688) |
0.192 (0.275) |
0.0143 (0.0376) |
0.00023 (0.00162) |
0.0122 (0.0336) |
0.00466 (0.0163) |
0.0497 (0.0987) |
0.0308 (0.0682) |
| 16q gain | 14 (9%) | 136 |
0.00747 (0.0233) |
0.14 (0.214) |
0.0673 (0.122) |
0.00862 (0.0258) |
0.00959 (0.0283) |
0.0492 (0.0981) |
0.0136 (0.0362) |
0.0129 (0.0349) |
0.00866 (0.0258) |
0.0543 (0.105) |
| 20q gain | 40 (27%) | 110 |
0.00715 (0.0227) |
0.00597 (0.0201) |
0.0582 (0.11) |
0.0543 (0.105) |
0.00695 (0.0224) |
0.0542 (0.105) |
0.046 (0.0929) |
0.0119 (0.0332) |
0.0154 (0.0397) |
0.0143 (0.0376) |
| 4q loss | 108 (72%) | 42 |
0.0674 (0.122) |
0.0106 (0.0305) |
0.68 (0.743) |
0.637 (0.711) |
0.0106 (0.0306) |
0.0122 (0.0337) |
0.0159 (0.0405) |
0.00504 (0.0175) |
0.0336 (0.072) |
0.0257 (0.0587) |
| 11p loss | 98 (65%) | 52 |
0.00862 (0.0258) |
0.182 (0.263) |
0.224 (0.309) |
0.217 (0.302) |
0.00047 (0.0028) |
0.00045 (0.00271) |
0.00109 (0.00576) |
0.0004 (0.00255) |
0.00166 (0.00793) |
0.00124 (0.00633) |
| 11q loss | 115 (77%) | 35 |
1e-05 (0.000128) |
0.122 (0.191) |
0.0694 (0.124) |
0.0712 (0.127) |
0.0001 (0.000813) |
2e-05 (0.000211) |
0.00043 (0.00267) |
5e-05 (0.000451) |
0.00091 (0.00492) |
1e-05 (0.000128) |
| 2p gain | 46 (31%) | 104 |
0.0139 (0.0368) |
0.00898 (0.0266) |
0.0233 (0.0541) |
0.0552 (0.106) |
0.0166 (0.0417) |
0.167 (0.246) |
0.0606 (0.112) |
0.0247 (0.0567) |
0.0313 (0.0689) |
0.0643 (0.118) |
| 7q gain | 105 (70%) | 45 |
0.548 (0.63) |
0.0689 (0.124) |
0.0739 (0.13) |
0.451 (0.536) |
0.00453 (0.0161) |
0.0116 (0.0326) |
0.00295 (0.0119) |
0.0025 (0.0105) |
0.00233 (0.01) |
0.00365 (0.0138) |
| 5q loss | 101 (67%) | 49 |
0.0569 (0.108) |
0.0606 (0.112) |
0.0432 (0.0886) |
0.315 (0.408) |
0.0132 (0.0354) |
0.00317 (0.0124) |
0.308 (0.402) |
0.0102 (0.0298) |
0.0199 (0.0484) |
0.00737 (0.0231) |
| 6q loss | 16 (11%) | 134 |
0.119 (0.189) |
0.0099 (0.0291) |
0.0348 (0.0742) |
0.0732 (0.129) |
0.0451 (0.0914) |
0.00124 (0.00633) |
0.109 (0.176) |
0.0275 (0.0622) |
0.0352 (0.0749) |
0.0998 (0.164) |
| 13q loss | 113 (75%) | 37 |
0.0441 (0.0899) |
0.289 (0.38) |
0.173 (0.253) |
0.0505 (0.0997) |
0.0331 (0.0713) |
0.00113 (0.00593) |
0.0432 (0.0886) |
0.0235 (0.0545) |
0.0998 (0.164) |
0.00173 (0.0082) |
| 17q loss | 16 (11%) | 134 |
0.00581 (0.0196) |
0.13 (0.201) |
0.517 (0.601) |
0.057 (0.108) |
0.0194 (0.0475) |
0.0284 (0.0639) |
0.0691 (0.124) |
0.014 (0.0369) |
0.0108 (0.0308) |
0.0048 (0.0168) |
| 5q gain | 3 (2%) | 147 |
0.778 (0.825) |
0.0589 (0.11) |
0.0361 (0.0765) |
0.0417 (0.0864) |
0.113 (0.181) |
0.0156 (0.0398) |
0.0126 (0.0343) |
0.0399 (0.083) |
||
| xq loss | 29 (19%) | 121 |
0.00039 (0.00253) |
0.00198 (0.00899) |
0.0909 (0.152) |
0.674 (0.739) |
0.161 (0.239) |
0.0957 (0.158) |
0.0251 (0.0576) |
0.0258 (0.0587) |
0.053 (0.104) |
0.00384 (0.0142) |
| 16p loss | 44 (29%) | 106 |
0.147 (0.222) |
0.00618 (0.0204) |
0.548 (0.63) |
0.297 (0.389) |
0.0795 (0.137) |
0.265 (0.355) |
0.00843 (0.0256) |
0.0112 (0.0318) |
0.0801 (0.137) |
0.21 (0.293) |
| xp loss | 29 (19%) | 121 |
0.00196 (0.00895) |
0.00184 (0.00862) |
0.266 (0.355) |
0.958 (0.98) |
0.164 (0.242) |
0.178 (0.258) |
0.0736 (0.13) |
0.0926 (0.154) |
0.0528 (0.104) |
0.00367 (0.0138) |
| 11q gain | 4 (3%) | 146 |
0.386 (0.47) |
0.152 (0.228) |
0.0164 (0.0413) |
0.153 (0.229) |
0.0774 (0.134) |
0.0125 (0.0341) |
0.379 (0.466) |
0.108 (0.175) |
0.106 (0.173) |
0.337 (0.426) |
| 12q gain | 100 (67%) | 50 |
0.565 (0.646) |
0.842 (0.88) |
0.251 (0.337) |
0.65 (0.72) |
0.204 (0.286) |
0.339 (0.428) |
0.0488 (0.0976) |
0.173 (0.253) |
0.0767 (0.134) |
0.0072 (0.0228) |
| 20p gain | 34 (23%) | 116 |
0.00517 (0.0178) |
0.113 (0.182) |
0.236 (0.323) |
0.198 (0.281) |
0.0419 (0.0865) |
0.285 (0.375) |
0.145 (0.22) |
0.147 (0.222) |
0.0615 (0.114) |
0.0631 (0.116) |
| 4p loss | 92 (61%) | 58 |
0.629 (0.705) |
0.0449 (0.0914) |
0.85 (0.887) |
0.666 (0.732) |
0.032 (0.0696) |
0.165 (0.243) |
0.103 (0.169) |
0.0796 (0.137) |
0.115 (0.183) |
0.334 (0.423) |
| 6p loss | 13 (9%) | 137 |
0.264 (0.354) |
0.0369 (0.078) |
0.0534 (0.104) |
0.0942 (0.157) |
0.159 (0.236) |
0.015 (0.0389) |
0.27 (0.359) |
0.114 (0.182) |
0.185 (0.266) |
0.32 (0.412) |
| 9q loss | 58 (39%) | 92 |
0.00035 (0.00229) |
0.338 (0.427) |
0.0663 (0.121) |
0.241 (0.327) |
0.309 (0.402) |
0.0176 (0.0439) |
0.656 (0.726) |
0.397 (0.479) |
0.367 (0.454) |
0.521 (0.604) |
| 18p loss | 116 (77%) | 34 |
0.69 (0.747) |
0.0743 (0.13) |
0.883 (0.914) |
0.7 (0.754) |
0.0454 (0.0917) |
0.242 (0.327) |
0.0873 (0.147) |
0.0159 (0.0406) |
0.276 (0.365) |
0.136 (0.209) |
| 18q loss | 122 (81%) | 28 |
0.0858 (0.144) |
0.316 (0.408) |
0.756 (0.804) |
0.873 (0.906) |
0.0666 (0.121) |
0.126 (0.196) |
0.0618 (0.114) |
0.0311 (0.0688) |
0.2 (0.283) |
0.0208 (0.0499) |
| 20p loss | 30 (20%) | 120 |
0.236 (0.323) |
0.187 (0.269) |
0.265 (0.355) |
0.467 (0.553) |
0.197 (0.28) |
0.17 (0.249) |
0.0154 (0.0397) |
0.148 (0.222) |
0.0809 (0.139) |
0.0262 (0.0594) |
| 1q gain | 61 (41%) | 89 |
0.442 (0.526) |
0.663 (0.731) |
0.0699 (0.125) |
0.55 (0.632) |
0.826 (0.867) |
0.06 (0.112) |
0.0377 (0.0792) |
0.636 (0.711) |
0.244 (0.33) |
0.0539 (0.105) |
| 2q gain | 42 (28%) | 108 |
0.117 (0.185) |
0.0342 (0.0732) |
0.911 (0.935) |
0.314 (0.407) |
0.278 (0.366) |
0.748 (0.799) |
0.488 (0.571) |
0.402 (0.484) |
0.348 (0.436) |
0.414 (0.496) |
| 21q gain | 125 (83%) | 25 |
0.404 (0.485) |
0.276 (0.365) |
0.0293 (0.0657) |
0.354 (0.443) |
0.0827 (0.141) |
0.238 (0.323) |
0.219 (0.304) |
0.0912 (0.152) |
0.128 (0.199) |
0.131 (0.202) |
| 1p loss | 18 (12%) | 132 |
0.122 (0.191) |
0.571 (0.651) |
0.39 (0.473) |
0.383 (0.469) |
0.648 (0.72) |
0.885 (0.914) |
0.0228 (0.0534) |
0.357 (0.444) |
0.131 (0.202) |
0.367 (0.454) |
| 3q loss | 22 (15%) | 128 |
0.742 (0.795) |
0.741 (0.794) |
0.127 (0.198) |
0.124 (0.194) |
0.0856 (0.144) |
0.0572 (0.108) |
0.0713 (0.127) |
0.0722 (0.128) |
0.0476 (0.0957) |
0.127 (0.198) |
| 9p loss | 63 (42%) | 87 |
0.0324 (0.0699) |
1 (1.00) |
0.347 (0.435) |
0.395 (0.478) |
0.869 (0.903) |
0.437 (0.522) |
0.781 (0.827) |
0.769 (0.817) |
0.91 (0.935) |
0.8 (0.845) |
| 16q loss | 51 (34%) | 99 |
0.0815 (0.139) |
0.0662 (0.121) |
0.935 (0.957) |
0.695 (0.749) |
0.231 (0.317) |
0.481 (0.567) |
0.0324 (0.0699) |
0.122 (0.191) |
0.33 (0.421) |
0.692 (0.748) |
| 4p gain | 3 (2%) | 147 |
0.637 (0.711) |
0.198 (0.281) |
0.853 (0.889) |
1 (1.00) |
1 (1.00) |
0.682 (0.743) |
0.491 (0.574) |
1 (1.00) |
1 (1.00) |
0.893 (0.922) |
| 9p gain | 16 (11%) | 134 |
0.232 (0.319) |
0.334 (0.424) |
0.468 (0.553) |
0.641 (0.714) |
0.159 (0.236) |
0.297 (0.389) |
0.22 (0.305) |
0.14 (0.214) |
0.175 (0.255) |
0.332 (0.423) |
| 9q gain | 17 (11%) | 133 |
0.154 (0.23) |
0.495 (0.576) |
0.566 (0.646) |
0.468 (0.553) |
1 (1.00) |
0.0771 (0.134) |
0.442 (0.526) |
0.896 (0.924) |
0.541 (0.626) |
0.382 (0.468) |
| 10p gain | 6 (4%) | 144 |
0.582 (0.662) |
0.0951 (0.158) |
0.322 (0.413) |
0.829 (0.869) |
0.322 (0.412) |
0.346 (0.435) |
0.15 (0.226) |
0.325 (0.415) |
0.368 (0.454) |
0.0585 (0.11) |
| 10q gain | 8 (5%) | 142 |
0.598 (0.674) |
0.387 (0.471) |
0.238 (0.323) |
0.175 (0.255) |
0.367 (0.454) |
0.226 (0.311) |
0.0554 (0.106) |
0.407 (0.488) |
0.518 (0.602) |
0.142 (0.216) |
| 11p gain | 10 (7%) | 140 |
0.274 (0.364) |
0.185 (0.266) |
0.11 (0.178) |
0.133 (0.205) |
0.162 (0.24) |
0.0527 (0.104) |
0.201 (0.283) |
0.199 (0.282) |
0.204 (0.286) |
0.356 (0.444) |
| 12p gain | 146 (97%) | 4 |
0.193 (0.276) |
0.388 (0.471) |
0.647 (0.72) |
0.539 (0.624) |
0.81 (0.853) |
0.37 (0.457) |
0.313 (0.407) |
0.584 (0.663) |
0.69 (0.747) |
0.0858 (0.144) |
| 14q gain | 51 (34%) | 99 |
0.252 (0.339) |
0.237 (0.323) |
0.75 (0.8) |
0.484 (0.568) |
0.588 (0.665) |
0.4 (0.482) |
0.822 (0.864) |
0.309 (0.402) |
0.203 (0.286) |
0.479 (0.565) |
| 18p gain | 4 (3%) | 146 |
0.685 (0.745) |
0.0702 (0.125) |
0.65 (0.72) |
1 (1.00) |
0.378 (0.466) |
0.782 (0.827) |
0.682 (0.743) |
0.483 (0.568) |
0.573 (0.652) |
0.684 (0.744) |
| 1q loss | 8 (5%) | 142 |
0.344 (0.434) |
0.246 (0.332) |
0.6 (0.676) |
0.689 (0.747) |
0.29 (0.381) |
0.216 (0.301) |
0.385 (0.47) |
0.329 (0.42) |
0.158 (0.236) |
0.598 (0.674) |
| 2p loss | 5 (3%) | 145 |
0.862 (0.897) |
0.379 (0.466) |
1 (1.00) |
1 (1.00) |
0.738 (0.793) |
1 (1.00) |
1 (1.00) |
0.81 (0.853) |
||
| 2q loss | 6 (4%) | 144 |
0.442 (0.526) |
0.677 (0.741) |
0.718 (0.773) |
0.601 (0.676) |
0.555 (0.637) |
0.899 (0.926) |
0.666 (0.732) |
0.659 (0.727) |
0.564 (0.646) |
1 (1.00) |
| 5p loss | 103 (69%) | 47 |
0.114 (0.182) |
0.212 (0.297) |
0.108 (0.176) |
0.542 (0.626) |
0.116 (0.185) |
0.133 (0.205) |
0.487 (0.57) |
0.0825 (0.141) |
0.112 (0.181) |
0.109 (0.177) |
| 20q loss | 15 (10%) | 135 |
0.585 (0.663) |
0.487 (0.57) |
0.745 (0.796) |
0.833 (0.872) |
0.2 (0.283) |
0.273 (0.363) |
0.0693 (0.124) |
0.142 (0.216) |
0.0994 (0.164) |
0.25 (0.337) |
P value = 0.00245 (Fisher's exact test), Q value = 0.01
Table S1. Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 1P GAIN MUTATED | 9 | 5 | 23 |
| 1P GAIN WILD-TYPE | 39 | 39 | 35 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0027
Table S2. Gene #1: '1p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 1P GAIN MUTATED | 8 | 22 | 7 |
| 1P GAIN WILD-TYPE | 48 | 27 | 38 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00289 (Fisher's exact test), Q value = 0.012
Table S3. Gene #1: '1p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 1P GAIN MUTATED | 7 | 5 | 8 | 12 |
| 1P GAIN WILD-TYPE | 41 | 9 | 27 | 9 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0148 (Fisher's exact test), Q value = 0.039
Table S4. Gene #1: '1p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 1P GAIN MUTATED | 7 | 8 | 17 |
| 1P GAIN WILD-TYPE | 43 | 17 | 26 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00044 (Fisher's exact test), Q value = 0.0027
Table S5. Gene #1: '1p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 1P GAIN MUTATED | 9 | 19 | 9 |
| 1P GAIN WILD-TYPE | 61 | 21 | 31 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00248 (Fisher's exact test), Q value = 0.01
Table S6. Gene #1: '1p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 1P GAIN MUTATED | 6 | 3 | 3 | 8 | 4 | 12 | 1 |
| 1P GAIN WILD-TYPE | 37 | 24 | 9 | 16 | 4 | 11 | 12 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00081
Table S7. Gene #1: '1p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 1P GAIN MUTATED | 4 | 24 | 9 |
| 1P GAIN WILD-TYPE | 48 | 33 | 32 |
Figure S7. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0013
Table S8. Gene #1: '1p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 1P GAIN MUTATED | 9 | 19 | 9 |
| 1P GAIN WILD-TYPE | 61 | 19 | 33 |
Figure S8. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S9. Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 1P GAIN MUTATED | 8 | 20 | 9 |
| 1P GAIN WILD-TYPE | 61 | 16 | 36 |
Figure S9. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00066 (Fisher's exact test), Q value = 0.0038
Table S10. Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 1P GAIN MUTATED | 5 | 4 | 19 | 9 |
| 1P GAIN WILD-TYPE | 32 | 29 | 19 | 33 |
Figure S10. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0377 (Fisher's exact test), Q value = 0.079
Table S11. Gene #2: '1q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 1Q GAIN MUTATED | 15 | 30 | 16 |
| 1Q GAIN WILD-TYPE | 37 | 27 | 25 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0139 (Fisher's exact test), Q value = 0.037
Table S12. Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 2P GAIN MUTATED | 10 | 10 | 26 |
| 2P GAIN WILD-TYPE | 38 | 34 | 32 |
Figure S12. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00898 (Fisher's exact test), Q value = 0.027
Table S13. Gene #3: '2p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 2P GAIN MUTATED | 9 | 18 | 19 |
| 2P GAIN WILD-TYPE | 47 | 31 | 26 |
Figure S13. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0233 (Fisher's exact test), Q value = 0.054
Table S14. Gene #3: '2p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 2P GAIN MUTATED | 8 | 5 | 11 | 11 |
| 2P GAIN WILD-TYPE | 40 | 9 | 24 | 10 |
Figure S14. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0166 (Fisher's exact test), Q value = 0.042
Table S15. Gene #3: '2p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 2P GAIN MUTATED | 14 | 14 | 18 |
| 2P GAIN WILD-TYPE | 56 | 26 | 22 |
Figure S15. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0247 (Fisher's exact test), Q value = 0.057
Table S16. Gene #3: '2p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 2P GAIN MUTATED | 14 | 14 | 18 |
| 2P GAIN WILD-TYPE | 56 | 24 | 24 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0313 (Fisher's exact test), Q value = 0.069
Table S17. Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 2P GAIN MUTATED | 14 | 13 | 19 |
| 2P GAIN WILD-TYPE | 55 | 23 | 26 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0342 (Fisher's exact test), Q value = 0.073
Table S18. Gene #4: '2q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 2Q GAIN MUTATED | 9 | 16 | 17 |
| 2Q GAIN WILD-TYPE | 47 | 33 | 28 |
Figure S18. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0219 (Fisher's exact test), Q value = 0.052
Table S19. Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 3P GAIN MUTATED | 5 | 5 | 17 |
| 3P GAIN WILD-TYPE | 43 | 39 | 41 |
Figure S19. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00156 (Fisher's exact test), Q value = 0.0075
Table S20. Gene #5: '3p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 3P GAIN MUTATED | 3 | 0 | 12 | 5 |
| 3P GAIN WILD-TYPE | 45 | 14 | 23 | 16 |
Figure S20. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0161 (Fisher's exact test), Q value = 0.041
Table S21. Gene #5: '3p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 3P GAIN MUTATED | 3 | 7 | 10 |
| 3P GAIN WILD-TYPE | 47 | 18 | 33 |
Figure S21. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00758 (Fisher's exact test), Q value = 0.023
Table S22. Gene #5: '3p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 3P GAIN MUTATED | 6 | 8 | 13 |
| 3P GAIN WILD-TYPE | 64 | 32 | 27 |
Figure S22. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.007 (Fisher's exact test), Q value = 0.022
Table S23. Gene #5: '3p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 3P GAIN MUTATED | 4 | 2 | 3 | 5 | 3 | 3 | 7 |
| 3P GAIN WILD-TYPE | 39 | 25 | 9 | 19 | 5 | 20 | 6 |
Figure S23. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0126 (Fisher's exact test), Q value = 0.034
Table S24. Gene #5: '3p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 3P GAIN MUTATED | 6 | 9 | 12 |
| 3P GAIN WILD-TYPE | 64 | 29 | 30 |
Figure S24. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0149 (Fisher's exact test), Q value = 0.039
Table S25. Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3P GAIN MUTATED | 6 | 8 | 13 |
| 3P GAIN WILD-TYPE | 63 | 28 | 32 |
Figure S25. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0111 (Fisher's exact test), Q value = 0.031
Table S26. Gene #5: '3p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 3P GAIN MUTATED | 5 | 1 | 8 | 13 |
| 3P GAIN WILD-TYPE | 32 | 32 | 30 | 29 |
Figure S26. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00688 (Fisher's exact test), Q value = 0.022
Table S27. Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 3Q GAIN MUTATED | 5 | 10 | 21 |
| 3Q GAIN WILD-TYPE | 43 | 34 | 37 |
Figure S27. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00511 (Fisher's exact test), Q value = 0.018
Table S28. Gene #6: '3q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 3Q GAIN MUTATED | 4 | 2 | 13 | 7 |
| 3Q GAIN WILD-TYPE | 44 | 12 | 22 | 14 |
Figure S28. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00528 (Fisher's exact test), Q value = 0.018
Table S29. Gene #6: '3q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 3Q GAIN MUTATED | 4 | 9 | 13 |
| 3Q GAIN WILD-TYPE | 46 | 16 | 30 |
Figure S29. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.032 (Fisher's exact test), Q value = 0.07
Table S30. Gene #6: '3q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 3Q GAIN MUTATED | 10 | 13 | 13 |
| 3Q GAIN WILD-TYPE | 60 | 27 | 27 |
Figure S30. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0323 (Fisher's exact test), Q value = 0.07
Table S31. Gene #6: '3q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 3Q GAIN MUTATED | 5 | 5 | 5 | 5 | 3 | 6 | 7 |
| 3Q GAIN WILD-TYPE | 38 | 22 | 7 | 19 | 5 | 17 | 6 |
Figure S31. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0214 (Fisher's exact test), Q value = 0.051
Table S32. Gene #6: '3q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 3Q GAIN MUTATED | 10 | 14 | 12 |
| 3Q GAIN WILD-TYPE | 60 | 24 | 30 |
Figure S32. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0391 (Fisher's exact test), Q value = 0.082
Table S33. Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3Q GAIN MUTATED | 10 | 12 | 14 |
| 3Q GAIN WILD-TYPE | 59 | 24 | 31 |
Figure S33. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0263 (Fisher's exact test), Q value = 0.059
Table S34. Gene #8: '5p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 55 | 44 | 45 |
Figure S34. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00799 (Fisher's exact test), Q value = 0.025
Table S35. Gene #8: '5p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 5P GAIN MUTATED | 1 | 0 | 0 | 4 |
| 5P GAIN WILD-TYPE | 47 | 14 | 35 | 17 |
Figure S35. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.032
Table S36. Gene #8: '5p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 69 | 35 | 40 |
Figure S36. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00803 (Fisher's exact test), Q value = 0.025
Table S37. Gene #8: '5p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 5P GAIN MUTATED | 0 | 1 | 0 | 0 | 2 | 3 | 0 |
| 5P GAIN WILD-TYPE | 43 | 26 | 12 | 24 | 6 | 20 | 13 |
Figure S37. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00456 (Fisher's exact test), Q value = 0.016
Table S38. Gene #8: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 5P GAIN MUTATED | 0 | 6 | 0 |
| 5P GAIN WILD-TYPE | 52 | 51 | 41 |
Figure S38. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00659 (Fisher's exact test), Q value = 0.021
Table S39. Gene #8: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 69 | 33 | 42 |
Figure S39. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.004 (Fisher's exact test), Q value = 0.015
Table S40. Gene #8: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 68 | 31 | 45 |
Figure S40. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00615 (Fisher's exact test), Q value = 0.02
Table S41. Gene #8: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 5P GAIN MUTATED | 0 | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 37 | 32 | 33 | 42 |
Figure S41. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0361 (Fisher's exact test), Q value = 0.077
Table S42. Gene #9: '5q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 5Q GAIN MUTATED | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 70 | 37 | 40 |
Figure S42. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0417 (Fisher's exact test), Q value = 0.086
Table S43. Gene #9: '5q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 5Q GAIN MUTATED | 0 | 0 | 0 | 0 | 1 | 2 | 0 |
| 5Q GAIN WILD-TYPE | 43 | 27 | 12 | 24 | 7 | 21 | 13 |
Figure S43. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0156 (Fisher's exact test), Q value = 0.04
Table S44. Gene #9: '5q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 5Q GAIN MUTATED | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 70 | 35 | 42 |
Figure S44. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0126 (Fisher's exact test), Q value = 0.034
Table S45. Gene #9: '5q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 5Q GAIN MUTATED | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 69 | 33 | 45 |
Figure S45. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0399 (Fisher's exact test), Q value = 0.083
Table S46. Gene #9: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 5Q GAIN MUTATED | 0 | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 37 | 33 | 35 | 42 |
Figure S46. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00042 (Fisher's exact test), Q value = 0.0026
Table S47. Gene #10: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 6P GAIN MUTATED | 9 | 1 | 18 |
| 6P GAIN WILD-TYPE | 39 | 43 | 40 |
Figure S47. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0376 (Fisher's exact test), Q value = 0.079
Table S48. Gene #10: '6p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 6P GAIN MUTATED | 6 | 9 | 6 |
| 6P GAIN WILD-TYPE | 44 | 16 | 37 |
Figure S48. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.013 (Fisher's exact test), Q value = 0.035
Table S49. Gene #10: '6p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 6P GAIN MUTATED | 9 | 5 | 14 |
| 6P GAIN WILD-TYPE | 61 | 35 | 26 |
Figure S49. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00096 (Fisher's exact test), Q value = 0.0051
Table S50. Gene #10: '6p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6P GAIN MUTATED | 8 | 1 | 0 | 12 | 0 | 5 | 2 |
| 6P GAIN WILD-TYPE | 35 | 26 | 12 | 12 | 8 | 18 | 11 |
Figure S50. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0179 (Fisher's exact test), Q value = 0.044
Table S51. Gene #10: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 6P GAIN MUTATED | 7 | 7 | 14 |
| 6P GAIN WILD-TYPE | 45 | 50 | 27 |
Figure S51. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00648 (Fisher's exact test), Q value = 0.021
Table S52. Gene #10: '6p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 6P GAIN MUTATED | 9 | 4 | 15 |
| 6P GAIN WILD-TYPE | 61 | 34 | 27 |
Figure S52. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0197 (Fisher's exact test), Q value = 0.048
Table S53. Gene #10: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 6P GAIN MUTATED | 7 | 2 | 5 | 14 |
| 6P GAIN WILD-TYPE | 30 | 31 | 33 | 28 |
Figure S53. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0223 (Fisher's exact test), Q value = 0.053
Table S54. Gene #11: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 6Q GAIN MUTATED | 7 | 2 | 14 |
| 6Q GAIN WILD-TYPE | 41 | 42 | 44 |
Figure S54. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0143 (Fisher's exact test), Q value = 0.038
Table S55. Gene #11: '6q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 6Q GAIN MUTATED | 8 | 3 | 12 |
| 6Q GAIN WILD-TYPE | 62 | 37 | 28 |
Figure S55. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0016
Table S56. Gene #11: '6q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6Q GAIN MUTATED | 8 | 0 | 0 | 11 | 0 | 3 | 1 |
| 6Q GAIN WILD-TYPE | 35 | 27 | 12 | 13 | 8 | 20 | 12 |
Figure S56. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0122 (Fisher's exact test), Q value = 0.034
Table S57. Gene #11: '6q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 6Q GAIN MUTATED | 7 | 4 | 12 |
| 6Q GAIN WILD-TYPE | 45 | 53 | 29 |
Figure S57. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00466 (Fisher's exact test), Q value = 0.016
Table S58. Gene #11: '6q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 6Q GAIN MUTATED | 8 | 2 | 13 |
| 6Q GAIN WILD-TYPE | 62 | 36 | 29 |
Figure S58. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0497 (Fisher's exact test), Q value = 0.099
Table S59. Gene #11: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 6Q GAIN MUTATED | 8 | 3 | 12 |
| 6Q GAIN WILD-TYPE | 61 | 33 | 33 |
Figure S59. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0308 (Fisher's exact test), Q value = 0.068
Table S60. Gene #11: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 6Q GAIN MUTATED | 6 | 2 | 3 | 12 |
| 6Q GAIN WILD-TYPE | 31 | 31 | 35 | 30 |
Figure S60. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00453 (Fisher's exact test), Q value = 0.016
Table S61. Gene #12: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 7P GAIN MUTATED | 34 | 42 | 45 |
| 7P GAIN WILD-TYPE | 14 | 2 | 13 |
Figure S61. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0231 (Fisher's exact test), Q value = 0.054
Table S62. Gene #12: '7p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 7P GAIN MUTATED | 42 | 10 | 22 | 19 |
| 7P GAIN WILD-TYPE | 6 | 4 | 13 | 2 |
Figure S62. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0203 (Fisher's exact test), Q value = 0.049
Table S63. Gene #12: '7p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 7P GAIN MUTATED | 44 | 15 | 34 |
| 7P GAIN WILD-TYPE | 6 | 10 | 9 |
Figure S63. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.004 (Fisher's exact test), Q value = 0.015
Table S64. Gene #12: '7p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 7P GAIN MUTATED | 62 | 34 | 25 |
| 7P GAIN WILD-TYPE | 8 | 6 | 15 |
Figure S64. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00866 (Fisher's exact test), Q value = 0.026
Table S65. Gene #12: '7p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 7P GAIN MUTATED | 38 | 24 | 7 | 16 | 6 | 22 | 8 |
| 7P GAIN WILD-TYPE | 5 | 3 | 5 | 8 | 2 | 1 | 5 |
Figure S65. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00818 (Fisher's exact test), Q value = 0.025
Table S66. Gene #12: '7p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 7P GAIN MUTATED | 45 | 50 | 26 |
| 7P GAIN WILD-TYPE | 7 | 7 | 15 |
Figure S66. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00748 (Fisher's exact test), Q value = 0.023
Table S67. Gene #12: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 7P GAIN MUTATED | 62 | 32 | 27 |
| 7P GAIN WILD-TYPE | 8 | 6 | 15 |
Figure S67. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00688 (Fisher's exact test), Q value = 0.022
Table S68. Gene #12: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 7P GAIN MUTATED | 61 | 31 | 29 |
| 7P GAIN WILD-TYPE | 8 | 5 | 16 |
Figure S68. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0226 (Fisher's exact test), Q value = 0.053
Table S69. Gene #12: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 7P GAIN MUTATED | 32 | 30 | 32 | 27 |
| 7P GAIN WILD-TYPE | 5 | 3 | 6 | 15 |
Figure S69. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00453 (Fisher's exact test), Q value = 0.016
Table S70. Gene #13: '7q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 7Q GAIN MUTATED | 52 | 33 | 20 |
| 7Q GAIN WILD-TYPE | 18 | 7 | 20 |
Figure S70. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0116 (Fisher's exact test), Q value = 0.033
Table S71. Gene #13: '7q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 7Q GAIN MUTATED | 36 | 16 | 8 | 11 | 6 | 20 | 8 |
| 7Q GAIN WILD-TYPE | 7 | 11 | 4 | 13 | 2 | 3 | 5 |
Figure S71. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00295 (Fisher's exact test), Q value = 0.012
Table S72. Gene #13: '7q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 7Q GAIN MUTATED | 39 | 46 | 20 |
| 7Q GAIN WILD-TYPE | 13 | 11 | 21 |
Figure S72. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0025 (Fisher's exact test), Q value = 0.011
Table S73. Gene #13: '7q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 7Q GAIN MUTATED | 52 | 32 | 21 |
| 7Q GAIN WILD-TYPE | 18 | 6 | 21 |
Figure S73. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00233 (Fisher's exact test), Q value = 0.01
Table S74. Gene #13: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 7Q GAIN MUTATED | 51 | 31 | 23 |
| 7Q GAIN WILD-TYPE | 18 | 5 | 22 |
Figure S74. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00365 (Fisher's exact test), Q value = 0.014
Table S75. Gene #13: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 7Q GAIN MUTATED | 30 | 22 | 32 | 21 |
| 7Q GAIN WILD-TYPE | 7 | 11 | 6 | 21 |
Figure S75. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00618 (Fisher's exact test), Q value = 0.02
Table S76. Gene #14: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 8P GAIN MUTATED | 49 | 33 | 28 |
| 8P GAIN WILD-TYPE | 7 | 16 | 17 |
Figure S76. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00026 (Fisher's exact test), Q value = 0.0018
Table S77. Gene #14: '8p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 8P GAIN MUTATED | 44 | 7 | 21 | 13 |
| 8P GAIN WILD-TYPE | 4 | 7 | 14 | 8 |
Figure S77. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0021
Table S78. Gene #14: '8p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 8P GAIN MUTATED | 45 | 12 | 28 |
| 8P GAIN WILD-TYPE | 5 | 13 | 15 |
Figure S78. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00037
Table S79. Gene #14: '8p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8P GAIN MUTATED | 63 | 26 | 21 |
| 8P GAIN WILD-TYPE | 7 | 14 | 19 |
Figure S79. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.0014
Table S80. Gene #14: '8p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8P GAIN MUTATED | 37 | 26 | 8 | 14 | 5 | 15 | 5 |
| 8P GAIN WILD-TYPE | 6 | 1 | 4 | 10 | 3 | 8 | 8 |
Figure S80. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00075
Table S81. Gene #14: '8p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8P GAIN MUTATED | 46 | 44 | 20 |
| 8P GAIN WILD-TYPE | 6 | 13 | 21 |
Figure S81. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 3e-04
Table S82. Gene #14: '8p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8P GAIN MUTATED | 63 | 26 | 21 |
| 8P GAIN WILD-TYPE | 7 | 12 | 21 |
Figure S82. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00053
Table S83. Gene #14: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8P GAIN MUTATED | 62 | 24 | 24 |
| 8P GAIN WILD-TYPE | 7 | 12 | 21 |
Figure S83. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00069
Table S84. Gene #14: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8P GAIN MUTATED | 32 | 31 | 26 | 21 |
| 8P GAIN WILD-TYPE | 5 | 2 | 12 | 21 |
Figure S84. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0208 (Fisher's exact test), Q value = 0.05
Table S85. Gene #15: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 8Q GAIN MUTATED | 34 | 39 | 38 |
| 8Q GAIN WILD-TYPE | 14 | 5 | 20 |
Figure S85. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00331 (Fisher's exact test), Q value = 0.013
Table S86. Gene #15: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 8Q GAIN MUTATED | 49 | 36 | 26 |
| 8Q GAIN WILD-TYPE | 7 | 13 | 19 |
Figure S86. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00457 (Fisher's exact test), Q value = 0.016
Table S87. Gene #15: '8q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 8Q GAIN MUTATED | 43 | 8 | 21 | 14 |
| 8Q GAIN WILD-TYPE | 5 | 6 | 14 | 7 |
Figure S87. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00361 (Fisher's exact test), Q value = 0.014
Table S88. Gene #15: '8q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 8Q GAIN MUTATED | 44 | 14 | 28 |
| 8Q GAIN WILD-TYPE | 6 | 11 | 15 |
Figure S88. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00075
Table S89. Gene #15: '8q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8Q GAIN MUTATED | 62 | 28 | 21 |
| 8Q GAIN WILD-TYPE | 8 | 12 | 19 |
Figure S89. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0023
Table S90. Gene #15: '8q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8Q GAIN MUTATED | 40 | 22 | 8 | 15 | 5 | 17 | 4 |
| 8Q GAIN WILD-TYPE | 3 | 5 | 4 | 9 | 3 | 6 | 9 |
Figure S90. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.001
Table S91. Gene #15: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8Q GAIN MUTATED | 47 | 43 | 21 |
| 8Q GAIN WILD-TYPE | 5 | 14 | 20 |
Figure S91. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00088
Table S92. Gene #15: '8q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8Q GAIN MUTATED | 62 | 27 | 22 |
| 8Q GAIN WILD-TYPE | 8 | 11 | 20 |
Figure S92. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00031 (Fisher's exact test), Q value = 0.0021
Table S93. Gene #15: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8Q GAIN MUTATED | 61 | 25 | 25 |
| 8Q GAIN WILD-TYPE | 8 | 11 | 20 |
Figure S93. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0016
Table S94. Gene #15: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8Q GAIN MUTATED | 34 | 28 | 27 | 22 |
| 8Q GAIN WILD-TYPE | 3 | 5 | 11 | 20 |
Figure S94. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0164 (Fisher's exact test), Q value = 0.041
Table S95. Gene #21: '11q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 11Q GAIN MUTATED | 0 | 0 | 1 | 3 |
| 11Q GAIN WILD-TYPE | 48 | 14 | 34 | 18 |
Figure S95. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0125 (Fisher's exact test), Q value = 0.034
Table S96. Gene #21: '11q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 11Q GAIN MUTATED | 0 | 0 | 0 | 0 | 1 | 1 | 2 |
| 11Q GAIN WILD-TYPE | 43 | 27 | 12 | 24 | 7 | 22 | 11 |
Figure S96. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0488 (Fisher's exact test), Q value = 0.098
Table S97. Gene #23: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 12Q GAIN MUTATED | 34 | 44 | 22 |
| 12Q GAIN WILD-TYPE | 18 | 13 | 19 |
Figure S97. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0072 (Fisher's exact test), Q value = 0.023
Table S98. Gene #23: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 12Q GAIN MUTATED | 21 | 29 | 27 | 23 |
| 12Q GAIN WILD-TYPE | 16 | 4 | 11 | 19 |
Figure S98. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00207 (Fisher's exact test), Q value = 0.0093
Table S99. Gene #25: '15q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 15Q GAIN MUTATED | 29 | 11 | 11 |
| 15Q GAIN WILD-TYPE | 27 | 38 | 34 |
Figure S99. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.00095
Table S100. Gene #25: '15q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 15Q GAIN MUTATED | 26 | 2 | 4 | 5 |
| 15Q GAIN WILD-TYPE | 22 | 12 | 31 | 16 |
Figure S100. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00079 (Fisher's exact test), Q value = 0.0044
Table S101. Gene #25: '15q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 15Q GAIN MUTATED | 25 | 3 | 9 |
| 15Q GAIN WILD-TYPE | 25 | 22 | 34 |
Figure S101. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S102. Gene #25: '15q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 15Q GAIN MUTATED | 38 | 8 | 5 |
| 15Q GAIN WILD-TYPE | 32 | 32 | 35 |
Figure S102. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S103. Gene #25: '15q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 15Q GAIN MUTATED | 26 | 12 | 1 | 4 | 0 | 7 | 1 |
| 15Q GAIN WILD-TYPE | 17 | 15 | 11 | 20 | 8 | 16 | 12 |
Figure S103. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00069
Table S104. Gene #25: '15q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 15Q GAIN MUTATED | 28 | 18 | 5 |
| 15Q GAIN WILD-TYPE | 24 | 39 | 36 |
Figure S104. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S105. Gene #25: '15q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 15Q GAIN MUTATED | 38 | 8 | 5 |
| 15Q GAIN WILD-TYPE | 32 | 30 | 37 |
Figure S105. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00037
Table S106. Gene #25: '15q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 15Q GAIN MUTATED | 37 | 8 | 6 |
| 15Q GAIN WILD-TYPE | 32 | 28 | 39 |
Figure S106. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S107. Gene #25: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 15Q GAIN MUTATED | 22 | 16 | 8 | 5 |
| 15Q GAIN WILD-TYPE | 15 | 17 | 30 | 37 |
Figure S107. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0121 (Fisher's exact test), Q value = 0.034
Table S108. Gene #26: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 16P GAIN MUTATED | 2 | 2 | 12 |
| 16P GAIN WILD-TYPE | 46 | 42 | 46 |
Figure S108. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00354 (Fisher's exact test), Q value = 0.014
Table S109. Gene #26: '16p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 16P GAIN MUTATED | 2 | 8 | 4 |
| 16P GAIN WILD-TYPE | 48 | 17 | 39 |
Figure S109. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00379 (Fisher's exact test), Q value = 0.014
Table S110. Gene #26: '16p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 16P GAIN MUTATED | 3 | 3 | 10 |
| 16P GAIN WILD-TYPE | 67 | 37 | 30 |
Figure S110. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0189 (Fisher's exact test), Q value = 0.047
Table S111. Gene #26: '16p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 16P GAIN MUTATED | 2 | 1 | 1 | 8 | 0 | 2 | 2 |
| 16P GAIN WILD-TYPE | 41 | 26 | 11 | 16 | 8 | 21 | 11 |
Figure S111. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00219 (Fisher's exact test), Q value = 0.0098
Table S112. Gene #26: '16p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16P GAIN MUTATED | 1 | 5 | 10 |
| 16P GAIN WILD-TYPE | 51 | 52 | 31 |
Figure S112. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00627 (Fisher's exact test), Q value = 0.021
Table S113. Gene #26: '16p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 16P GAIN MUTATED | 3 | 3 | 10 |
| 16P GAIN WILD-TYPE | 67 | 35 | 32 |
Figure S113. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00262 (Fisher's exact test), Q value = 0.011
Table S114. Gene #26: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 16P GAIN MUTATED | 3 | 2 | 11 |
| 16P GAIN WILD-TYPE | 66 | 34 | 34 |
Figure S114. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0204 (Fisher's exact test), Q value = 0.049
Table S115. Gene #26: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 16P GAIN MUTATED | 2 | 1 | 3 | 10 |
| 16P GAIN WILD-TYPE | 35 | 32 | 35 | 32 |
Figure S115. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00747 (Fisher's exact test), Q value = 0.023
Table S116. Gene #27: '16q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 16Q GAIN MUTATED | 2 | 1 | 11 |
| 16Q GAIN WILD-TYPE | 46 | 43 | 47 |
Figure S116. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00862 (Fisher's exact test), Q value = 0.026
Table S117. Gene #27: '16q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 16Q GAIN MUTATED | 1 | 6 | 4 |
| 16Q GAIN WILD-TYPE | 49 | 19 | 39 |
Figure S117. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00959 (Fisher's exact test), Q value = 0.028
Table S118. Gene #27: '16q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 16Q GAIN MUTATED | 2 | 4 | 8 |
| 16Q GAIN WILD-TYPE | 68 | 36 | 32 |
Figure S118. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0492 (Fisher's exact test), Q value = 0.098
Table S119. Gene #27: '16q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 16Q GAIN MUTATED | 1 | 1 | 1 | 6 | 0 | 3 | 2 |
| 16Q GAIN WILD-TYPE | 42 | 26 | 11 | 18 | 8 | 20 | 11 |
Figure S119. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0136 (Fisher's exact test), Q value = 0.036
Table S120. Gene #27: '16q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16Q GAIN MUTATED | 1 | 5 | 8 |
| 16Q GAIN WILD-TYPE | 51 | 52 | 33 |
Figure S120. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0129 (Fisher's exact test), Q value = 0.035
Table S121. Gene #27: '16q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 16Q GAIN MUTATED | 2 | 4 | 8 |
| 16Q GAIN WILD-TYPE | 68 | 34 | 34 |
Figure S121. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00866 (Fisher's exact test), Q value = 0.026
Table S122. Gene #27: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 16Q GAIN MUTATED | 2 | 3 | 9 |
| 16Q GAIN WILD-TYPE | 67 | 33 | 36 |
Figure S122. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S123. Gene #28: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17P GAIN MUTATED | 9 | 2 | 29 |
| 17P GAIN WILD-TYPE | 39 | 42 | 29 |
Figure S123. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S124. Gene #28: '17p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 17P GAIN MUTATED | 3 | 23 | 14 |
| 17P GAIN WILD-TYPE | 53 | 26 | 31 |
Figure S124. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S125. Gene #28: '17p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 17P GAIN MUTATED | 2 | 4 | 14 | 10 |
| 17P GAIN WILD-TYPE | 46 | 10 | 21 | 11 |
Figure S125. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S126. Gene #28: '17p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 17P GAIN MUTATED | 2 | 11 | 17 |
| 17P GAIN WILD-TYPE | 48 | 14 | 26 |
Figure S126. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S127. Gene #28: '17p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17P GAIN MUTATED | 3 | 19 | 18 |
| 17P GAIN WILD-TYPE | 67 | 21 | 22 |
Figure S127. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S128. Gene #28: '17p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17P GAIN MUTATED | 2 | 1 | 5 | 11 | 4 | 12 | 5 |
| 17P GAIN WILD-TYPE | 41 | 26 | 7 | 13 | 4 | 11 | 8 |
Figure S128. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S129. Gene #28: '17p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 17P GAIN MUTATED | 2 | 21 | 17 |
| 17P GAIN WILD-TYPE | 50 | 36 | 24 |
Figure S129. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S130. Gene #28: '17p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17P GAIN MUTATED | 3 | 19 | 18 |
| 17P GAIN WILD-TYPE | 67 | 19 | 24 |
Figure S130. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S131. Gene #28: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17P GAIN MUTATED | 3 | 17 | 20 |
| 17P GAIN WILD-TYPE | 66 | 19 | 25 |
Figure S131. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S132. Gene #28: '17p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17P GAIN MUTATED | 1 | 2 | 20 | 17 |
| 17P GAIN WILD-TYPE | 36 | 31 | 18 | 25 |
Figure S132. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.0012
Table S133. Gene #29: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17Q GAIN MUTATED | 13 | 7 | 31 |
| 17Q GAIN WILD-TYPE | 35 | 37 | 27 |
Figure S133. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00045
Table S134. Gene #29: '17q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 17Q GAIN MUTATED | 8 | 27 | 16 |
| 17Q GAIN WILD-TYPE | 48 | 22 | 29 |
Figure S134. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00037
Table S135. Gene #29: '17q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 17Q GAIN MUTATED | 5 | 5 | 18 | 12 |
| 17Q GAIN WILD-TYPE | 43 | 9 | 17 | 9 |
Figure S135. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S136. Gene #29: '17q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 17Q GAIN MUTATED | 5 | 13 | 22 |
| 17Q GAIN WILD-TYPE | 45 | 12 | 21 |
Figure S136. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S137. Gene #29: '17q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17Q GAIN MUTATED | 7 | 23 | 21 |
| 17Q GAIN WILD-TYPE | 63 | 17 | 19 |
Figure S137. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S138. Gene #29: '17q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17Q GAIN MUTATED | 4 | 3 | 6 | 13 | 4 | 15 | 6 |
| 17Q GAIN WILD-TYPE | 39 | 24 | 6 | 11 | 4 | 8 | 7 |
Figure S138. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S139. Gene #29: '17q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 17Q GAIN MUTATED | 4 | 26 | 21 |
| 17Q GAIN WILD-TYPE | 48 | 31 | 20 |
Figure S139. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S140. Gene #29: '17q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17Q GAIN MUTATED | 7 | 22 | 22 |
| 17Q GAIN WILD-TYPE | 63 | 16 | 20 |
Figure S140. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S141. Gene #29: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17Q GAIN MUTATED | 6 | 21 | 24 |
| 17Q GAIN WILD-TYPE | 63 | 15 | 21 |
Figure S141. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S142. Gene #29: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17Q GAIN MUTATED | 2 | 5 | 22 | 22 |
| 17Q GAIN WILD-TYPE | 35 | 28 | 16 | 20 |
Figure S142. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0105 (Fisher's exact test), Q value = 0.03
Table S143. Gene #31: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19P GAIN MUTATED | 8 | 18 | 10 |
| 19P GAIN WILD-TYPE | 40 | 26 | 48 |
Figure S143. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.0012
Table S144. Gene #31: '19p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19P GAIN MUTATED | 23 | 3 | 10 |
| 19P GAIN WILD-TYPE | 33 | 46 | 35 |
Figure S144. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00264 (Fisher's exact test), Q value = 0.011
Table S145. Gene #31: '19p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 19P GAIN MUTATED | 21 | 1 | 5 | 3 |
| 19P GAIN WILD-TYPE | 27 | 13 | 30 | 18 |
Figure S145. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00206 (Fisher's exact test), Q value = 0.0093
Table S146. Gene #31: '19p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 19P GAIN MUTATED | 21 | 3 | 6 |
| 19P GAIN WILD-TYPE | 29 | 22 | 37 |
Figure S146. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00075
Table S147. Gene #31: '19p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19P GAIN MUTATED | 28 | 3 | 5 |
| 19P GAIN WILD-TYPE | 42 | 37 | 35 |
Figure S147. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00085 (Fisher's exact test), Q value = 0.0047
Table S148. Gene #31: '19p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19P GAIN MUTATED | 14 | 14 | 0 | 4 | 0 | 3 | 1 |
| 19P GAIN WILD-TYPE | 29 | 13 | 12 | 20 | 8 | 20 | 12 |
Figure S148. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0435 (Fisher's exact test), Q value = 0.089
Table S149. Gene #31: '19p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 19P GAIN MUTATED | 18 | 13 | 5 |
| 19P GAIN WILD-TYPE | 34 | 44 | 36 |
Figure S149. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00069
Table S150. Gene #31: '19p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19P GAIN MUTATED | 28 | 2 | 6 |
| 19P GAIN WILD-TYPE | 42 | 36 | 36 |
Figure S150. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00051 (Fisher's exact test), Q value = 0.003
Table S151. Gene #31: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19P GAIN MUTATED | 27 | 4 | 5 |
| 19P GAIN WILD-TYPE | 42 | 32 | 40 |
Figure S151. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00037
Table S152. Gene #31: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19P GAIN MUTATED | 10 | 18 | 3 | 5 |
| 19P GAIN WILD-TYPE | 27 | 15 | 35 | 37 |
Figure S152. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0163 (Fisher's exact test), Q value = 0.041
Table S153. Gene #32: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19Q GAIN MUTATED | 7 | 15 | 7 |
| 19Q GAIN WILD-TYPE | 41 | 29 | 51 |
Figure S153. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.001
Table S154. Gene #32: '19q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19Q GAIN MUTATED | 20 | 2 | 7 |
| 19Q GAIN WILD-TYPE | 36 | 47 | 38 |
Figure S154. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00224 (Fisher's exact test), Q value = 0.0098
Table S155. Gene #32: '19q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 19Q GAIN MUTATED | 18 | 1 | 4 | 1 |
| 19Q GAIN WILD-TYPE | 30 | 13 | 31 | 20 |
Figure S155. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00191 (Fisher's exact test), Q value = 0.0088
Table S156. Gene #32: '19q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 19Q GAIN MUTATED | 18 | 2 | 4 |
| 19Q GAIN WILD-TYPE | 32 | 23 | 39 |
Figure S156. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S157. Gene #32: '19q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19Q GAIN MUTATED | 24 | 1 | 4 |
| 19Q GAIN WILD-TYPE | 46 | 39 | 36 |
Figure S157. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00063 (Fisher's exact test), Q value = 0.0036
Table S158. Gene #32: '19q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19Q GAIN MUTATED | 11 | 13 | 0 | 3 | 0 | 1 | 1 |
| 19Q GAIN WILD-TYPE | 32 | 14 | 12 | 21 | 8 | 22 | 12 |
Figure S158. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 3e-04
Table S159. Gene #32: '19q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19Q GAIN MUTATED | 24 | 1 | 4 |
| 19Q GAIN WILD-TYPE | 46 | 37 | 38 |
Figure S159. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00041 (Fisher's exact test), Q value = 0.0026
Table S160. Gene #32: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19Q GAIN MUTATED | 23 | 2 | 4 |
| 19Q GAIN WILD-TYPE | 46 | 34 | 41 |
Figure S160. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S161. Gene #32: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19Q GAIN MUTATED | 8 | 16 | 1 | 4 |
| 19Q GAIN WILD-TYPE | 29 | 17 | 37 | 38 |
Figure S161. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00517 (Fisher's exact test), Q value = 0.018
Table S162. Gene #33: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 20P GAIN MUTATED | 5 | 8 | 21 |
| 20P GAIN WILD-TYPE | 43 | 36 | 37 |
Figure S162. Get High-res Image Gene #33: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0419 (Fisher's exact test), Q value = 0.087
Table S163. Gene #33: '20p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 20P GAIN MUTATED | 12 | 7 | 15 |
| 20P GAIN WILD-TYPE | 58 | 33 | 25 |
Figure S163. Get High-res Image Gene #33: '20p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00715 (Fisher's exact test), Q value = 0.023
Table S164. Gene #34: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 20Q GAIN MUTATED | 8 | 8 | 24 |
| 20Q GAIN WILD-TYPE | 40 | 36 | 34 |
Figure S164. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00597 (Fisher's exact test), Q value = 0.02
Table S165. Gene #34: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 20Q GAIN MUTATED | 7 | 16 | 17 |
| 20Q GAIN WILD-TYPE | 49 | 33 | 28 |
Figure S165. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00695 (Fisher's exact test), Q value = 0.022
Table S166. Gene #34: '20q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 20Q GAIN MUTATED | 12 | 10 | 18 |
| 20Q GAIN WILD-TYPE | 58 | 30 | 22 |
Figure S166. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.046 (Fisher's exact test), Q value = 0.093
Table S167. Gene #34: '20q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 20Q GAIN MUTATED | 10 | 13 | 17 |
| 20Q GAIN WILD-TYPE | 42 | 44 | 24 |
Figure S167. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0119 (Fisher's exact test), Q value = 0.033
Table S168. Gene #34: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 20Q GAIN MUTATED | 12 | 10 | 18 |
| 20Q GAIN WILD-TYPE | 58 | 28 | 24 |
Figure S168. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0154 (Fisher's exact test), Q value = 0.04
Table S169. Gene #34: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 20Q GAIN MUTATED | 12 | 9 | 19 |
| 20Q GAIN WILD-TYPE | 57 | 27 | 26 |
Figure S169. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0143 (Fisher's exact test), Q value = 0.038
Table S170. Gene #34: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 20Q GAIN MUTATED | 4 | 8 | 10 | 18 |
| 20Q GAIN WILD-TYPE | 33 | 25 | 28 | 24 |
Figure S170. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0293 (Fisher's exact test), Q value = 0.066
Table S171. Gene #35: '21q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 21Q GAIN MUTATED | 44 | 8 | 29 | 17 |
| 21Q GAIN WILD-TYPE | 4 | 6 | 6 | 4 |
Figure S171. Get High-res Image Gene #35: '21q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S172. Gene #36: '22q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 22Q GAIN MUTATED | 9 | 23 | 6 |
| 22Q GAIN WILD-TYPE | 39 | 21 | 52 |
Figure S172. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00121 (Fisher's exact test), Q value = 0.0063
Table S173. Gene #36: '22q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 22Q GAIN MUTATED | 21 | 4 | 13 |
| 22Q GAIN WILD-TYPE | 35 | 45 | 32 |
Figure S173. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00125 (Fisher's exact test), Q value = 0.0063
Table S174. Gene #36: '22q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 22Q GAIN MUTATED | 20 | 3 | 2 | 4 |
| 22Q GAIN WILD-TYPE | 28 | 11 | 33 | 17 |
Figure S174. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0022
Table S175. Gene #36: '22q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 22Q GAIN MUTATED | 21 | 1 | 7 |
| 22Q GAIN WILD-TYPE | 29 | 24 | 36 |
Figure S175. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 3e-04
Table S176. Gene #36: '22q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 22Q GAIN MUTATED | 30 | 3 | 5 |
| 22Q GAIN WILD-TYPE | 40 | 37 | 35 |
Figure S176. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S177. Gene #36: '22q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 22Q GAIN MUTATED | 11 | 19 | 1 | 4 | 1 | 1 | 1 |
| 22Q GAIN WILD-TYPE | 32 | 8 | 11 | 20 | 7 | 22 | 12 |
Figure S177. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S178. Gene #36: '22q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 22Q GAIN MUTATED | 30 | 3 | 5 |
| 22Q GAIN WILD-TYPE | 40 | 35 | 37 |
Figure S178. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00045
Table S179. Gene #36: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 22Q GAIN MUTATED | 29 | 4 | 5 |
| 22Q GAIN WILD-TYPE | 40 | 32 | 40 |
Figure S179. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S180. Gene #36: '22q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 22Q GAIN MUTATED | 10 | 20 | 3 | 5 |
| 22Q GAIN WILD-TYPE | 27 | 13 | 35 | 37 |
Figure S180. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-04 (Fisher's exact test), Q value = 0.0026
Table S181. Gene #37: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XP GAIN MUTATED | 3 | 2 | 17 |
| XP GAIN WILD-TYPE | 45 | 42 | 41 |
Figure S181. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.047
Table S182. Gene #37: 'xp gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XP GAIN MUTATED | 3 | 8 | 11 |
| XP GAIN WILD-TYPE | 53 | 41 | 34 |
Figure S182. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0316 (Fisher's exact test), Q value = 0.069
Table S183. Gene #37: 'xp gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| XP GAIN MUTATED | 3 | 2 | 9 | 6 |
| XP GAIN WILD-TYPE | 45 | 12 | 26 | 15 |
Figure S183. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.013 (Fisher's exact test), Q value = 0.035
Table S184. Gene #37: 'xp gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| XP GAIN MUTATED | 3 | 5 | 12 |
| XP GAIN WILD-TYPE | 47 | 20 | 31 |
Figure S184. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00058 (Fisher's exact test), Q value = 0.0034
Table S185. Gene #37: 'xp gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| XP GAIN MUTATED | 3 | 7 | 12 |
| XP GAIN WILD-TYPE | 67 | 33 | 28 |
Figure S185. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00303 (Fisher's exact test), Q value = 0.012
Table S186. Gene #37: 'xp gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| XP GAIN MUTATED | 2 | 1 | 3 | 7 | 0 | 4 | 5 |
| XP GAIN WILD-TYPE | 41 | 26 | 9 | 17 | 8 | 19 | 8 |
Figure S186. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 8e-04 (Fisher's exact test), Q value = 0.0044
Table S187. Gene #37: 'xp gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| XP GAIN MUTATED | 2 | 7 | 13 |
| XP GAIN WILD-TYPE | 50 | 50 | 28 |
Figure S187. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.0015
Table S188. Gene #37: 'xp gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| XP GAIN MUTATED | 3 | 5 | 14 |
| XP GAIN WILD-TYPE | 67 | 33 | 28 |
Figure S188. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00174 (Fisher's exact test), Q value = 0.0082
Table S189. Gene #37: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| XP GAIN MUTATED | 3 | 7 | 12 |
| XP GAIN WILD-TYPE | 66 | 29 | 33 |
Figure S189. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00399 (Fisher's exact test), Q value = 0.015
Table S190. Gene #37: 'xp gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XP GAIN MUTATED | 2 | 1 | 7 | 12 |
| XP GAIN WILD-TYPE | 35 | 32 | 31 | 30 |
Figure S190. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00189 (Fisher's exact test), Q value = 0.0087
Table S191. Gene #38: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XQ GAIN MUTATED | 4 | 2 | 16 |
| XQ GAIN WILD-TYPE | 44 | 42 | 42 |
Figure S191. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0182 (Fisher's exact test), Q value = 0.045
Table S192. Gene #38: 'xq gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XQ GAIN MUTATED | 3 | 8 | 11 |
| XQ GAIN WILD-TYPE | 53 | 41 | 34 |
Figure S192. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0431 (Fisher's exact test), Q value = 0.089
Table S193. Gene #38: 'xq gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| XQ GAIN MUTATED | 3 | 3 | 8 | 6 |
| XQ GAIN WILD-TYPE | 45 | 11 | 27 | 15 |
Figure S193. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0195 (Fisher's exact test), Q value = 0.048
Table S194. Gene #38: 'xq gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| XQ GAIN MUTATED | 3 | 6 | 11 |
| XQ GAIN WILD-TYPE | 47 | 19 | 32 |
Figure S194. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00075 (Fisher's exact test), Q value = 0.0042
Table S195. Gene #38: 'xq gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| XQ GAIN MUTATED | 3 | 7 | 12 |
| XQ GAIN WILD-TYPE | 67 | 33 | 28 |
Figure S195. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00377 (Fisher's exact test), Q value = 0.014
Table S196. Gene #38: 'xq gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| XQ GAIN MUTATED | 2 | 1 | 2 | 7 | 0 | 5 | 5 |
| XQ GAIN WILD-TYPE | 41 | 26 | 10 | 17 | 8 | 18 | 8 |
Figure S196. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00257 (Fisher's exact test), Q value = 0.011
Table S197. Gene #38: 'xq gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| XQ GAIN MUTATED | 2 | 8 | 12 |
| XQ GAIN WILD-TYPE | 50 | 49 | 29 |
Figure S197. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00035 (Fisher's exact test), Q value = 0.0023
Table S198. Gene #38: 'xq gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| XQ GAIN MUTATED | 3 | 6 | 13 |
| XQ GAIN WILD-TYPE | 67 | 32 | 29 |
Figure S198. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00139 (Fisher's exact test), Q value = 0.0069
Table S199. Gene #38: 'xq gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| XQ GAIN MUTATED | 3 | 7 | 12 |
| XQ GAIN WILD-TYPE | 66 | 29 | 33 |
Figure S199. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00457 (Fisher's exact test), Q value = 0.016
Table S200. Gene #38: 'xq gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XQ GAIN MUTATED | 2 | 1 | 7 | 12 |
| XQ GAIN WILD-TYPE | 35 | 32 | 31 | 30 |
Figure S200. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0228 (Fisher's exact test), Q value = 0.053
Table S201. Gene #39: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 1P LOSS MUTATED | 10 | 2 | 6 |
| 1P LOSS WILD-TYPE | 42 | 55 | 35 |
Figure S201. Get High-res Image Gene #39: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0301 (Fisher's exact test), Q value = 0.067
Table S202. Gene #43: '3p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 3P LOSS MUTATED | 11 | 15 | 4 |
| 3P LOSS WILD-TYPE | 45 | 34 | 41 |
Figure S202. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00297 (Fisher's exact test), Q value = 0.012
Table S203. Gene #43: '3p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 3P LOSS MUTATED | 10 | 3 | 0 | 6 |
| 3P LOSS WILD-TYPE | 38 | 11 | 35 | 15 |
Figure S203. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00145 (Fisher's exact test), Q value = 0.0072
Table S204. Gene #43: '3p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 3P LOSS MUTATED | 17 | 12 | 1 |
| 3P LOSS WILD-TYPE | 53 | 28 | 39 |
Figure S204. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00317 (Fisher's exact test), Q value = 0.012
Table S205. Gene #43: '3p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 3P LOSS MUTATED | 13 | 4 | 1 | 1 | 1 | 10 | 0 |
| 3P LOSS WILD-TYPE | 30 | 23 | 11 | 23 | 7 | 13 | 13 |
Figure S205. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00108 (Fisher's exact test), Q value = 0.0057
Table S206. Gene #43: '3p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 3P LOSS MUTATED | 13 | 16 | 1 |
| 3P LOSS WILD-TYPE | 39 | 41 | 40 |
Figure S206. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00065 (Fisher's exact test), Q value = 0.0037
Table S207. Gene #43: '3p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 3P LOSS MUTATED | 17 | 12 | 1 |
| 3P LOSS WILD-TYPE | 53 | 26 | 41 |
Figure S207. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00293 (Fisher's exact test), Q value = 0.012
Table S208. Gene #43: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3P LOSS MUTATED | 17 | 11 | 2 |
| 3P LOSS WILD-TYPE | 52 | 25 | 43 |
Figure S208. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00153 (Fisher's exact test), Q value = 0.0075
Table S209. Gene #43: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 3P LOSS MUTATED | 10 | 7 | 12 | 1 |
| 3P LOSS WILD-TYPE | 27 | 26 | 26 | 41 |
Figure S209. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0476 (Fisher's exact test), Q value = 0.096
Table S210. Gene #44: '3q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3Q LOSS MUTATED | 14 | 6 | 2 |
| 3Q LOSS WILD-TYPE | 55 | 30 | 43 |
Figure S210. Get High-res Image Gene #44: '3q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0449 (Fisher's exact test), Q value = 0.091
Table S211. Gene #45: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 4P LOSS MUTATED | 36 | 35 | 21 |
| 4P LOSS WILD-TYPE | 20 | 14 | 24 |
Figure S211. Get High-res Image Gene #45: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.032 (Fisher's exact test), Q value = 0.07
Table S212. Gene #45: '4p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 4P LOSS MUTATED | 45 | 29 | 18 |
| 4P LOSS WILD-TYPE | 25 | 11 | 22 |
Figure S212. Get High-res Image Gene #45: '4p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0106 (Fisher's exact test), Q value = 0.031
Table S213. Gene #46: '4q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 4Q LOSS MUTATED | 40 | 42 | 26 |
| 4Q LOSS WILD-TYPE | 16 | 7 | 19 |
Figure S213. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0106 (Fisher's exact test), Q value = 0.031
Table S214. Gene #46: '4q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 4Q LOSS MUTATED | 50 | 35 | 23 |
| 4Q LOSS WILD-TYPE | 20 | 5 | 17 |
Figure S214. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0122 (Fisher's exact test), Q value = 0.034
Table S215. Gene #46: '4q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 4Q LOSS MUTATED | 27 | 23 | 10 | 13 | 7 | 21 | 7 |
| 4Q LOSS WILD-TYPE | 16 | 4 | 2 | 11 | 1 | 2 | 6 |
Figure S215. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0159 (Fisher's exact test), Q value = 0.041
Table S216. Gene #46: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 4Q LOSS MUTATED | 36 | 48 | 24 |
| 4Q LOSS WILD-TYPE | 16 | 9 | 17 |
Figure S216. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00504 (Fisher's exact test), Q value = 0.018
Table S217. Gene #46: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 4Q LOSS MUTATED | 50 | 34 | 24 |
| 4Q LOSS WILD-TYPE | 20 | 4 | 18 |
Figure S217. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0336 (Fisher's exact test), Q value = 0.072
Table S218. Gene #46: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 4Q LOSS MUTATED | 50 | 31 | 27 |
| 4Q LOSS WILD-TYPE | 19 | 5 | 18 |
Figure S218. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0257 (Fisher's exact test), Q value = 0.059
Table S219. Gene #46: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 4Q LOSS MUTATED | 24 | 26 | 33 | 25 |
| 4Q LOSS WILD-TYPE | 13 | 7 | 5 | 17 |
Figure S219. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0432 (Fisher's exact test), Q value = 0.089
Table S220. Gene #48: '5q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 5Q LOSS MUTATED | 36 | 7 | 24 | 9 |
| 5Q LOSS WILD-TYPE | 12 | 7 | 11 | 12 |
Figure S220. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0132 (Fisher's exact test), Q value = 0.035
Table S221. Gene #48: '5q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 5Q LOSS MUTATED | 55 | 21 | 25 |
| 5Q LOSS WILD-TYPE | 15 | 19 | 15 |
Figure S221. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00317 (Fisher's exact test), Q value = 0.012
Table S222. Gene #48: '5q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 5Q LOSS MUTATED | 29 | 26 | 8 | 15 | 3 | 12 | 8 |
| 5Q LOSS WILD-TYPE | 14 | 1 | 4 | 9 | 5 | 11 | 5 |
Figure S222. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0102 (Fisher's exact test), Q value = 0.03
Table S223. Gene #48: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 5Q LOSS MUTATED | 55 | 19 | 27 |
| 5Q LOSS WILD-TYPE | 15 | 19 | 15 |
Figure S223. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0199 (Fisher's exact test), Q value = 0.048
Table S224. Gene #48: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 5Q LOSS MUTATED | 54 | 19 | 28 |
| 5Q LOSS WILD-TYPE | 15 | 17 | 17 |
Figure S224. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00737 (Fisher's exact test), Q value = 0.023
Table S225. Gene #48: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 5Q LOSS MUTATED | 27 | 28 | 18 | 28 |
| 5Q LOSS WILD-TYPE | 10 | 5 | 20 | 14 |
Figure S225. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0369 (Fisher's exact test), Q value = 0.078
Table S226. Gene #49: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 6P LOSS MUTATED | 1 | 7 | 5 |
| 6P LOSS WILD-TYPE | 55 | 42 | 40 |
Figure S226. Get High-res Image Gene #49: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.015 (Fisher's exact test), Q value = 0.039
Table S227. Gene #49: '6p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6P LOSS MUTATED | 1 | 2 | 2 | 0 | 1 | 3 | 4 |
| 6P LOSS WILD-TYPE | 42 | 25 | 10 | 24 | 7 | 20 | 9 |
Figure S227. Get High-res Image Gene #49: '6p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0099 (Fisher's exact test), Q value = 0.029
Table S228. Gene #50: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 6Q LOSS MUTATED | 1 | 9 | 6 |
| 6Q LOSS WILD-TYPE | 55 | 40 | 39 |
Figure S228. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0348 (Fisher's exact test), Q value = 0.074
Table S229. Gene #50: '6q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 6Q LOSS MUTATED | 2 | 1 | 4 | 6 |
| 6Q LOSS WILD-TYPE | 46 | 13 | 31 | 15 |
Figure S229. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0451 (Fisher's exact test), Q value = 0.091
Table S230. Gene #50: '6q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 6Q LOSS MUTATED | 3 | 7 | 6 |
| 6Q LOSS WILD-TYPE | 67 | 33 | 34 |
Figure S230. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00124 (Fisher's exact test), Q value = 0.0063
Table S231. Gene #50: '6q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6Q LOSS MUTATED | 1 | 2 | 2 | 0 | 2 | 4 | 5 |
| 6Q LOSS WILD-TYPE | 42 | 25 | 10 | 24 | 6 | 19 | 8 |
Figure S231. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0275 (Fisher's exact test), Q value = 0.062
Table S232. Gene #50: '6q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 6Q LOSS MUTATED | 3 | 8 | 5 |
| 6Q LOSS WILD-TYPE | 67 | 30 | 37 |
Figure S232. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0352 (Fisher's exact test), Q value = 0.075
Table S233. Gene #50: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 6Q LOSS MUTATED | 3 | 7 | 6 |
| 6Q LOSS WILD-TYPE | 66 | 29 | 39 |
Figure S233. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0495 (Fisher's exact test), Q value = 0.098
Table S234. Gene #51: '8p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 8P LOSS MUTATED | 1 | 7 | 4 |
| 8P LOSS WILD-TYPE | 55 | 42 | 41 |
Figure S234. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.01 (Fisher's exact test), Q value = 0.029
Table S235. Gene #51: '8p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 8P LOSS MUTATED | 0 | 0 | 5 | 3 |
| 8P LOSS WILD-TYPE | 48 | 14 | 30 | 18 |
Figure S235. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00732 (Fisher's exact test), Q value = 0.023
Table S236. Gene #51: '8p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 8P LOSS MUTATED | 0 | 4 | 4 |
| 8P LOSS WILD-TYPE | 50 | 21 | 39 |
Figure S236. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0108 (Fisher's exact test), Q value = 0.031
Table S237. Gene #51: '8p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8P LOSS MUTATED | 1 | 5 | 6 |
| 8P LOSS WILD-TYPE | 69 | 35 | 34 |
Figure S237. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0478 (Fisher's exact test), Q value = 0.096
Table S238. Gene #51: '8p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8P LOSS MUTATED | 1 | 0 | 1 | 3 | 1 | 3 | 3 |
| 8P LOSS WILD-TYPE | 42 | 27 | 11 | 21 | 7 | 20 | 10 |
Figure S238. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00805 (Fisher's exact test), Q value = 0.025
Table S239. Gene #51: '8p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8P LOSS MUTATED | 1 | 3 | 8 |
| 8P LOSS WILD-TYPE | 51 | 54 | 33 |
Figure S239. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00188 (Fisher's exact test), Q value = 0.0087
Table S240. Gene #51: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8P LOSS MUTATED | 1 | 3 | 8 |
| 8P LOSS WILD-TYPE | 69 | 35 | 34 |
Figure S240. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00708 (Fisher's exact test), Q value = 0.023
Table S241. Gene #51: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8P LOSS MUTATED | 1 | 4 | 7 |
| 8P LOSS WILD-TYPE | 68 | 32 | 38 |
Figure S241. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0227 (Fisher's exact test), Q value = 0.053
Table S242. Gene #51: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8P LOSS MUTATED | 1 | 0 | 4 | 7 |
| 8P LOSS WILD-TYPE | 36 | 33 | 34 | 35 |
Figure S242. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0243 (Fisher's exact test), Q value = 0.056
Table S243. Gene #52: '8q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 8Q LOSS MUTATED | 0 | 1 | 4 |
| 8Q LOSS WILD-TYPE | 56 | 48 | 41 |
Figure S243. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0239 (Fisher's exact test), Q value = 0.055
Table S244. Gene #52: '8q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 8Q LOSS MUTATED | 0 | 0 | 4 | 0 |
| 8Q LOSS WILD-TYPE | 48 | 14 | 31 | 21 |
Figure S244. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0145 (Fisher's exact test), Q value = 0.038
Table S245. Gene #52: '8q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 8Q LOSS MUTATED | 0 | 3 | 1 |
| 8Q LOSS WILD-TYPE | 50 | 22 | 42 |
Figure S245. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00233 (Fisher's exact test), Q value = 0.01
Table S246. Gene #52: '8q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 70 | 40 | 35 |
Figure S246. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.012 (Fisher's exact test), Q value = 0.033
Table S247. Gene #52: '8q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8Q LOSS MUTATED | 0 | 0 | 0 | 3 | 0 | 0 | 2 |
| 8Q LOSS WILD-TYPE | 43 | 27 | 12 | 21 | 8 | 23 | 11 |
Figure S247. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00124 (Fisher's exact test), Q value = 0.0063
Table S248. Gene #52: '8q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 52 | 57 | 36 |
Figure S248. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0023 (Fisher's exact test), Q value = 0.01
Table S249. Gene #52: '8q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 70 | 38 | 37 |
Figure S249. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00266 (Fisher's exact test), Q value = 0.011
Table S250. Gene #52: '8q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 69 | 36 | 40 |
Figure S250. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00346 (Fisher's exact test), Q value = 0.013
Table S251. Gene #52: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8Q LOSS MUTATED | 0 | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 37 | 33 | 38 | 37 |
Figure S251. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0324 (Fisher's exact test), Q value = 0.07
Table S252. Gene #53: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 9P LOSS MUTATED | 15 | 16 | 32 |
| 9P LOSS WILD-TYPE | 33 | 28 | 26 |
Figure S252. Get High-res Image Gene #53: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00035 (Fisher's exact test), Q value = 0.0023
Table S253. Gene #54: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 9Q LOSS MUTATED | 11 | 13 | 34 |
| 9Q LOSS WILD-TYPE | 37 | 31 | 24 |
Figure S253. Get High-res Image Gene #54: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0176 (Fisher's exact test), Q value = 0.044
Table S254. Gene #54: '9q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 9Q LOSS MUTATED | 13 | 10 | 8 | 13 | 0 | 11 | 3 |
| 9Q LOSS WILD-TYPE | 30 | 17 | 4 | 11 | 8 | 12 | 10 |
Figure S254. Get High-res Image Gene #54: '9q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0215 (Fisher's exact test), Q value = 0.051
Table S255. Gene #55: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 10P LOSS MUTATED | 20 | 19 | 38 |
| 10P LOSS WILD-TYPE | 28 | 25 | 20 |
Figure S255. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00044 (Fisher's exact test), Q value = 0.0027
Table S256. Gene #55: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 10P LOSS MUTATED | 20 | 36 | 21 |
| 10P LOSS WILD-TYPE | 36 | 13 | 24 |
Figure S256. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00603 (Fisher's exact test), Q value = 0.02
Table S257. Gene #55: '10p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 10P LOSS MUTATED | 17 | 6 | 22 | 16 |
| 10P LOSS WILD-TYPE | 31 | 8 | 13 | 5 |
Figure S257. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0129 (Fisher's exact test), Q value = 0.035
Table S258. Gene #55: '10p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 10P LOSS MUTATED | 18 | 15 | 28 |
| 10P LOSS WILD-TYPE | 32 | 10 | 15 |
Figure S258. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00026 (Fisher's exact test), Q value = 0.0018
Table S259. Gene #55: '10p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 10P LOSS MUTATED | 27 | 31 | 19 |
| 10P LOSS WILD-TYPE | 43 | 9 | 21 |
Figure S259. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00553 (Fisher's exact test), Q value = 0.019
Table S260. Gene #55: '10p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 10P LOSS MUTATED | 16 | 11 | 9 | 13 | 6 | 18 | 4 |
| 10P LOSS WILD-TYPE | 27 | 16 | 3 | 11 | 2 | 5 | 9 |
Figure S260. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0378 (Fisher's exact test), Q value = 0.079
Table S261. Gene #55: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 10P LOSS MUTATED | 20 | 36 | 21 |
| 10P LOSS WILD-TYPE | 32 | 21 | 20 |
Figure S261. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00088 (Fisher's exact test), Q value = 0.0048
Table S262. Gene #55: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 10P LOSS MUTATED | 27 | 29 | 21 |
| 10P LOSS WILD-TYPE | 43 | 9 | 21 |
Figure S262. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00222 (Fisher's exact test), Q value = 0.0098
Table S263. Gene #55: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 10P LOSS MUTATED | 27 | 27 | 23 |
| 10P LOSS WILD-TYPE | 42 | 9 | 22 |
Figure S263. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0013 (Fisher's exact test), Q value = 0.0065
Table S264. Gene #55: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 10P LOSS MUTATED | 12 | 15 | 29 | 21 |
| 10P LOSS WILD-TYPE | 25 | 18 | 9 | 21 |
Figure S264. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00888 (Fisher's exact test), Q value = 0.026
Table S265. Gene #56: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 10Q LOSS MUTATED | 19 | 16 | 37 |
| 10Q LOSS WILD-TYPE | 29 | 28 | 21 |
Figure S265. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S266. Gene #56: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 10Q LOSS MUTATED | 16 | 36 | 20 |
| 10Q LOSS WILD-TYPE | 40 | 13 | 25 |
Figure S266. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0013
Table S267. Gene #56: '10q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 10Q LOSS MUTATED | 24 | 30 | 18 |
| 10Q LOSS WILD-TYPE | 46 | 10 | 22 |
Figure S267. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00222 (Fisher's exact test), Q value = 0.0098
Table S268. Gene #56: '10q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 10Q LOSS MUTATED | 16 | 8 | 9 | 12 | 5 | 18 | 4 |
| 10Q LOSS WILD-TYPE | 27 | 19 | 3 | 12 | 3 | 5 | 9 |
Figure S268. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.032 (Fisher's exact test), Q value = 0.07
Table S269. Gene #56: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 10Q LOSS MUTATED | 18 | 34 | 20 |
| 10Q LOSS WILD-TYPE | 34 | 23 | 21 |
Figure S269. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00055 (Fisher's exact test), Q value = 0.0032
Table S270. Gene #56: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 10Q LOSS MUTATED | 24 | 28 | 20 |
| 10Q LOSS WILD-TYPE | 46 | 10 | 22 |
Figure S270. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00154 (Fisher's exact test), Q value = 0.0075
Table S271. Gene #56: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 10Q LOSS MUTATED | 24 | 26 | 22 |
| 10Q LOSS WILD-TYPE | 45 | 10 | 23 |
Figure S271. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00152 (Fisher's exact test), Q value = 0.0075
Table S272. Gene #56: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 10Q LOSS MUTATED | 12 | 12 | 28 | 20 |
| 10Q LOSS WILD-TYPE | 25 | 21 | 10 | 22 |
Figure S272. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00862 (Fisher's exact test), Q value = 0.026
Table S273. Gene #57: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 11P LOSS MUTATED | 25 | 36 | 37 |
| 11P LOSS WILD-TYPE | 23 | 8 | 21 |
Figure S273. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00047 (Fisher's exact test), Q value = 0.0028
Table S274. Gene #57: '11p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 11P LOSS MUTATED | 54 | 28 | 16 |
| 11P LOSS WILD-TYPE | 16 | 12 | 24 |
Figure S274. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.0027
Table S275. Gene #57: '11p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 11P LOSS MUTATED | 32 | 22 | 8 | 12 | 4 | 18 | 2 |
| 11P LOSS WILD-TYPE | 11 | 5 | 4 | 12 | 4 | 5 | 11 |
Figure S275. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00109 (Fisher's exact test), Q value = 0.0058
Table S276. Gene #57: '11p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 11P LOSS MUTATED | 38 | 43 | 17 |
| 11P LOSS WILD-TYPE | 14 | 14 | 24 |
Figure S276. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 4e-04 (Fisher's exact test), Q value = 0.0026
Table S277. Gene #57: '11p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 11P LOSS MUTATED | 54 | 27 | 17 |
| 11P LOSS WILD-TYPE | 16 | 11 | 25 |
Figure S277. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00166 (Fisher's exact test), Q value = 0.0079
Table S278. Gene #57: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 11P LOSS MUTATED | 53 | 25 | 20 |
| 11P LOSS WILD-TYPE | 16 | 11 | 25 |
Figure S278. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00124 (Fisher's exact test), Q value = 0.0063
Table S279. Gene #57: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 11P LOSS MUTATED | 28 | 26 | 27 | 17 |
| 11P LOSS WILD-TYPE | 9 | 7 | 11 | 25 |
Figure S279. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S280. Gene #58: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 11Q LOSS MUTATED | 30 | 44 | 41 |
| 11Q LOSS WILD-TYPE | 18 | 0 | 17 |
Figure S280. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00081
Table S281. Gene #58: '11q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 11Q LOSS MUTATED | 62 | 32 | 21 |
| 11Q LOSS WILD-TYPE | 8 | 8 | 19 |
Figure S281. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S282. Gene #58: '11q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 11Q LOSS MUTATED | 35 | 27 | 11 | 15 | 6 | 18 | 3 |
| 11Q LOSS WILD-TYPE | 8 | 0 | 1 | 9 | 2 | 5 | 10 |
Figure S282. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00043 (Fisher's exact test), Q value = 0.0027
Table S283. Gene #58: '11q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 11Q LOSS MUTATED | 44 | 49 | 22 |
| 11Q LOSS WILD-TYPE | 8 | 8 | 19 |
Figure S283. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00045
Table S284. Gene #58: '11q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 11Q LOSS MUTATED | 62 | 31 | 22 |
| 11Q LOSS WILD-TYPE | 8 | 7 | 20 |
Figure S284. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00091 (Fisher's exact test), Q value = 0.0049
Table S285. Gene #58: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 11Q LOSS MUTATED | 61 | 28 | 26 |
| 11Q LOSS WILD-TYPE | 8 | 8 | 19 |
Figure S285. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S286. Gene #58: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 11Q LOSS MUTATED | 29 | 33 | 30 | 23 |
| 11Q LOSS WILD-TYPE | 8 | 0 | 8 | 19 |
Figure S286. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0441 (Fisher's exact test), Q value = 0.09
Table S287. Gene #59: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 13Q LOSS MUTATED | 34 | 39 | 40 |
| 13Q LOSS WILD-TYPE | 14 | 5 | 18 |
Figure S287. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0331 (Fisher's exact test), Q value = 0.071
Table S288. Gene #59: '13q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 13Q LOSS MUTATED | 58 | 31 | 24 |
| 13Q LOSS WILD-TYPE | 12 | 9 | 16 |
Figure S288. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00113 (Fisher's exact test), Q value = 0.0059
Table S289. Gene #59: '13q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 13Q LOSS MUTATED | 31 | 27 | 11 | 14 | 6 | 17 | 7 |
| 13Q LOSS WILD-TYPE | 12 | 0 | 1 | 10 | 2 | 6 | 6 |
Figure S289. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0432 (Fisher's exact test), Q value = 0.089
Table S290. Gene #59: '13q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 13Q LOSS MUTATED | 43 | 45 | 25 |
| 13Q LOSS WILD-TYPE | 9 | 12 | 16 |
Figure S290. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0235 (Fisher's exact test), Q value = 0.055
Table S291. Gene #59: '13q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 13Q LOSS MUTATED | 58 | 30 | 25 |
| 13Q LOSS WILD-TYPE | 12 | 8 | 17 |
Figure S291. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00173 (Fisher's exact test), Q value = 0.0082
Table S292. Gene #59: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 13Q LOSS MUTATED | 26 | 32 | 29 | 26 |
| 13Q LOSS WILD-TYPE | 11 | 1 | 9 | 16 |
Figure S292. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00068 (Fisher's exact test), Q value = 0.0038
Table S293. Gene #60: '14q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 14Q LOSS MUTATED | 2 | 14 | 4 |
| 14Q LOSS WILD-TYPE | 54 | 35 | 41 |
Figure S293. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0299 (Fisher's exact test), Q value = 0.067
Table S294. Gene #60: '14q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 14Q LOSS MUTATED | 3 | 2 | 4 | 7 |
| 14Q LOSS WILD-TYPE | 45 | 12 | 31 | 14 |
Figure S294. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00448 (Fisher's exact test), Q value = 0.016
Table S295. Gene #60: '14q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 14Q LOSS MUTATED | 3 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 67 | 30 | 33 |
Figure S295. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S296. Gene #60: '14q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 14Q LOSS MUTATED | 0 | 3 | 0 | 5 | 0 | 10 | 2 |
| 14Q LOSS WILD-TYPE | 43 | 24 | 12 | 19 | 8 | 13 | 11 |
Figure S296. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0302 (Fisher's exact test), Q value = 0.067
Table S297. Gene #60: '14q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 14Q LOSS MUTATED | 2 | 11 | 7 |
| 14Q LOSS WILD-TYPE | 50 | 46 | 34 |
Figure S297. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0032 (Fisher's exact test), Q value = 0.012
Table S298. Gene #60: '14q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 14Q LOSS MUTATED | 3 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 67 | 28 | 35 |
Figure S298. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00288 (Fisher's exact test), Q value = 0.012
Table S299. Gene #60: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 14Q LOSS MUTATED | 3 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 66 | 26 | 38 |
Figure S299. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0116 (Fisher's exact test), Q value = 0.033
Table S300. Gene #60: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 14Q LOSS MUTATED | 1 | 2 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 36 | 31 | 28 | 35 |
Figure S300. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0058 (Fisher's exact test), Q value = 0.02
Table S301. Gene #61: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 15Q LOSS MUTATED | 11 | 2 | 16 |
| 15Q LOSS WILD-TYPE | 37 | 42 | 42 |
Figure S301. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S302. Gene #61: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 15Q LOSS MUTATED | 1 | 17 | 11 |
| 15Q LOSS WILD-TYPE | 55 | 32 | 34 |
Figure S302. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S303. Gene #61: '15q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 15Q LOSS MUTATED | 0 | 4 | 13 | 8 |
| 15Q LOSS WILD-TYPE | 48 | 10 | 22 | 13 |
Figure S303. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S304. Gene #61: '15q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 15Q LOSS MUTATED | 0 | 10 | 15 |
| 15Q LOSS WILD-TYPE | 50 | 15 | 28 |
Figure S304. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S305. Gene #61: '15q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 15Q LOSS MUTATED | 1 | 13 | 15 |
| 15Q LOSS WILD-TYPE | 69 | 27 | 25 |
Figure S305. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S306. Gene #61: '15q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 15Q LOSS MUTATED | 0 | 1 | 3 | 7 | 4 | 8 | 6 |
| 15Q LOSS WILD-TYPE | 43 | 26 | 9 | 17 | 4 | 15 | 7 |
Figure S306. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S307. Gene #61: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 15Q LOSS MUTATED | 0 | 14 | 15 |
| 15Q LOSS WILD-TYPE | 52 | 43 | 26 |
Figure S307. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S308. Gene #61: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 15Q LOSS MUTATED | 1 | 13 | 15 |
| 15Q LOSS WILD-TYPE | 69 | 25 | 27 |
Figure S308. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S309. Gene #61: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 15Q LOSS MUTATED | 1 | 12 | 16 |
| 15Q LOSS WILD-TYPE | 68 | 24 | 29 |
Figure S309. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S310. Gene #61: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 15Q LOSS MUTATED | 0 | 1 | 13 | 15 |
| 15Q LOSS WILD-TYPE | 37 | 32 | 25 | 27 |
Figure S310. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00618 (Fisher's exact test), Q value = 0.02
Table S311. Gene #62: '16p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 16P LOSS MUTATED | 17 | 21 | 6 |
| 16P LOSS WILD-TYPE | 39 | 28 | 39 |
Figure S311. Get High-res Image Gene #62: '16p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00843 (Fisher's exact test), Q value = 0.026
Table S312. Gene #62: '16p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16P LOSS MUTATED | 12 | 25 | 7 |
| 16P LOSS WILD-TYPE | 40 | 32 | 34 |
Figure S312. Get High-res Image Gene #62: '16p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0112 (Fisher's exact test), Q value = 0.032
Table S313. Gene #62: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 16P LOSS MUTATED | 19 | 18 | 7 |
| 16P LOSS WILD-TYPE | 51 | 20 | 35 |
Figure S313. Get High-res Image Gene #62: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0324 (Fisher's exact test), Q value = 0.07
Table S314. Gene #63: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16Q LOSS MUTATED | 13 | 27 | 11 |
| 16Q LOSS WILD-TYPE | 39 | 30 | 30 |
Figure S314. Get High-res Image Gene #63: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S315. Gene #64: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17P LOSS MUTATED | 5 | 23 | 9 |
| 17P LOSS WILD-TYPE | 43 | 21 | 49 |
Figure S315. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0397 (Fisher's exact test), Q value = 0.083
Table S316. Gene #64: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 17P LOSS MUTATED | 18 | 6 | 13 |
| 17P LOSS WILD-TYPE | 38 | 43 | 32 |
Figure S316. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0174 (Fisher's exact test), Q value = 0.044
Table S317. Gene #64: '17p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 17P LOSS MUTATED | 18 | 2 | 7 | 1 |
| 17P LOSS WILD-TYPE | 30 | 12 | 28 | 20 |
Figure S317. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.003 (Fisher's exact test), Q value = 0.012
Table S318. Gene #64: '17p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 17P LOSS MUTATED | 19 | 1 | 8 |
| 17P LOSS WILD-TYPE | 31 | 24 | 35 |
Figure S318. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00436 (Fisher's exact test), Q value = 0.016
Table S319. Gene #64: '17p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17P LOSS MUTATED | 26 | 5 | 6 |
| 17P LOSS WILD-TYPE | 44 | 35 | 34 |
Figure S319. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0016
Table S320. Gene #64: '17p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17P LOSS MUTATED | 10 | 16 | 2 | 1 | 0 | 4 | 4 |
| 17P LOSS WILD-TYPE | 33 | 11 | 10 | 23 | 8 | 19 | 9 |
Figure S320. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00361 (Fisher's exact test), Q value = 0.014
Table S321. Gene #64: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17P LOSS MUTATED | 26 | 4 | 7 |
| 17P LOSS WILD-TYPE | 44 | 34 | 35 |
Figure S321. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00163 (Fisher's exact test), Q value = 0.0078
Table S322. Gene #64: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17P LOSS MUTATED | 26 | 3 | 8 |
| 17P LOSS WILD-TYPE | 43 | 33 | 37 |
Figure S322. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 3e-04
Table S323. Gene #64: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17P LOSS MUTATED | 7 | 19 | 3 | 8 |
| 17P LOSS WILD-TYPE | 30 | 14 | 35 | 34 |
Figure S323. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00581 (Fisher's exact test), Q value = 0.02
Table S324. Gene #65: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17Q LOSS MUTATED | 1 | 10 | 5 |
| 17Q LOSS WILD-TYPE | 47 | 34 | 53 |
Figure S324. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.047
Table S325. Gene #65: '17q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17Q LOSS MUTATED | 13 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 57 | 38 | 39 |
Figure S325. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0284 (Fisher's exact test), Q value = 0.064
Table S326. Gene #65: '17q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17Q LOSS MUTATED | 5 | 8 | 0 | 0 | 0 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 38 | 19 | 12 | 24 | 8 | 21 | 12 |
Figure S326. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.014 (Fisher's exact test), Q value = 0.037
Table S327. Gene #65: '17q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17Q LOSS MUTATED | 13 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 57 | 36 | 41 |
Figure S327. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0108 (Fisher's exact test), Q value = 0.031
Table S328. Gene #65: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17Q LOSS MUTATED | 13 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 56 | 34 | 44 |
Figure S328. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0048 (Fisher's exact test), Q value = 0.017
Table S329. Gene #65: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17Q LOSS MUTATED | 4 | 9 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 33 | 24 | 36 | 41 |
Figure S329. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0454 (Fisher's exact test), Q value = 0.092
Table S330. Gene #66: '18p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 18P LOSS MUTATED | 53 | 36 | 27 |
| 18P LOSS WILD-TYPE | 17 | 4 | 13 |
Figure S330. Get High-res Image Gene #66: '18p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0159 (Fisher's exact test), Q value = 0.041
Table S331. Gene #66: '18p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 18P LOSS MUTATED | 53 | 35 | 28 |
| 18P LOSS WILD-TYPE | 17 | 3 | 14 |
Figure S331. Get High-res Image Gene #66: '18p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0311 (Fisher's exact test), Q value = 0.069
Table S332. Gene #67: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 18Q LOSS MUTATED | 58 | 35 | 29 |
| 18Q LOSS WILD-TYPE | 12 | 3 | 13 |
Figure S332. Get High-res Image Gene #67: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0208 (Fisher's exact test), Q value = 0.05
Table S333. Gene #67: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 18Q LOSS MUTATED | 27 | 31 | 34 | 30 |
| 18Q LOSS WILD-TYPE | 10 | 2 | 4 | 12 |
Figure S333. Get High-res Image Gene #67: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S334. Gene #68: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19P LOSS MUTATED | 12 | 5 | 33 |
| 19P LOSS WILD-TYPE | 36 | 39 | 25 |
Figure S334. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S335. Gene #68: '19p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19P LOSS MUTATED | 2 | 31 | 17 |
| 19P LOSS WILD-TYPE | 54 | 18 | 28 |
Figure S335. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S336. Gene #68: '19p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 19P LOSS MUTATED | 2 | 6 | 19 | 14 |
| 19P LOSS WILD-TYPE | 46 | 8 | 16 | 7 |
Figure S336. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S337. Gene #68: '19p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 19P LOSS MUTATED | 2 | 14 | 25 |
| 19P LOSS WILD-TYPE | 48 | 11 | 18 |
Figure S337. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S338. Gene #68: '19p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19P LOSS MUTATED | 2 | 27 | 21 |
| 19P LOSS WILD-TYPE | 68 | 13 | 19 |
Figure S338. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S339. Gene #68: '19p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19P LOSS MUTATED | 0 | 2 | 9 | 12 | 5 | 16 | 6 |
| 19P LOSS WILD-TYPE | 43 | 25 | 3 | 12 | 3 | 7 | 7 |
Figure S339. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S340. Gene #68: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 19P LOSS MUTATED | 1 | 28 | 21 |
| 19P LOSS WILD-TYPE | 51 | 29 | 20 |
Figure S340. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S341. Gene #68: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19P LOSS MUTATED | 2 | 27 | 21 |
| 19P LOSS WILD-TYPE | 68 | 11 | 21 |
Figure S341. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S342. Gene #68: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19P LOSS MUTATED | 2 | 24 | 24 |
| 19P LOSS WILD-TYPE | 67 | 12 | 21 |
Figure S342. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S343. Gene #68: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19P LOSS MUTATED | 0 | 2 | 26 | 22 |
| 19P LOSS WILD-TYPE | 37 | 31 | 12 | 20 |
Figure S343. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S344. Gene #69: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19Q LOSS MUTATED | 11 | 7 | 35 |
| 19Q LOSS WILD-TYPE | 37 | 37 | 23 |
Figure S344. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S345. Gene #69: '19q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19Q LOSS MUTATED | 1 | 34 | 18 |
| 19Q LOSS WILD-TYPE | 55 | 15 | 27 |
Figure S345. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S346. Gene #69: '19q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 19Q LOSS MUTATED | 1 | 6 | 20 | 16 |
| 19Q LOSS WILD-TYPE | 47 | 8 | 15 | 5 |
Figure S346. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S347. Gene #69: '19q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 19Q LOSS MUTATED | 1 | 14 | 28 |
| 19Q LOSS WILD-TYPE | 49 | 11 | 15 |
Figure S347. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S348. Gene #69: '19q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19Q LOSS MUTATED | 1 | 30 | 22 |
| 19Q LOSS WILD-TYPE | 69 | 10 | 18 |
Figure S348. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S349. Gene #69: '19q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19Q LOSS MUTATED | 0 | 1 | 9 | 13 | 5 | 19 | 6 |
| 19Q LOSS WILD-TYPE | 43 | 26 | 3 | 11 | 3 | 4 | 7 |
Figure S349. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S350. Gene #69: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 19Q LOSS MUTATED | 1 | 30 | 22 |
| 19Q LOSS WILD-TYPE | 51 | 27 | 19 |
Figure S350. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S351. Gene #69: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19Q LOSS MUTATED | 1 | 30 | 22 |
| 19Q LOSS WILD-TYPE | 69 | 8 | 20 |
Figure S351. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S352. Gene #69: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19Q LOSS MUTATED | 1 | 27 | 25 |
| 19Q LOSS WILD-TYPE | 68 | 9 | 20 |
Figure S352. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S353. Gene #69: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19Q LOSS MUTATED | 0 | 1 | 29 | 23 |
| 19Q LOSS WILD-TYPE | 37 | 32 | 9 | 19 |
Figure S353. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0154 (Fisher's exact test), Q value = 0.04
Table S354. Gene #70: '20p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 20P LOSS MUTATED | 5 | 18 | 7 |
| 20P LOSS WILD-TYPE | 47 | 39 | 34 |
Figure S354. Get High-res Image Gene #70: '20p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0262 (Fisher's exact test), Q value = 0.059
Table S355. Gene #70: '20p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 20P LOSS MUTATED | 3 | 8 | 13 | 6 |
| 20P LOSS WILD-TYPE | 34 | 25 | 25 | 36 |
Figure S355. Get High-res Image Gene #70: '20p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00239 (Fisher's exact test), Q value = 0.01
Table S356. Gene #72: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 22Q LOSS MUTATED | 9 | 9 | 27 |
| 22Q LOSS WILD-TYPE | 39 | 35 | 31 |
Figure S356. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S357. Gene #72: '22q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 22Q LOSS MUTATED | 4 | 28 | 13 |
| 22Q LOSS WILD-TYPE | 52 | 21 | 32 |
Figure S357. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0013
Table S358. Gene #72: '22q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 48 | 14 | 35 | 21 |
| 22Q LOSS MUTATED | 4 | 6 | 15 | 10 |
| 22Q LOSS WILD-TYPE | 44 | 8 | 20 | 11 |
Figure S358. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S359. Gene #72: '22q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 50 | 25 | 43 |
| 22Q LOSS MUTATED | 4 | 15 | 16 |
| 22Q LOSS WILD-TYPE | 46 | 10 | 27 |
Figure S359. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S360. Gene #72: '22q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 22Q LOSS MUTATED | 6 | 23 | 16 |
| 22Q LOSS WILD-TYPE | 64 | 17 | 24 |
Figure S360. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S361. Gene #72: '22q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 22Q LOSS MUTATED | 5 | 1 | 7 | 10 | 4 | 13 | 5 |
| 22Q LOSS WILD-TYPE | 38 | 26 | 5 | 14 | 4 | 10 | 8 |
Figure S361. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00037
Table S362. Gene #72: '22q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 22Q LOSS MUTATED | 4 | 24 | 17 |
| 22Q LOSS WILD-TYPE | 48 | 33 | 24 |
Figure S362. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S363. Gene #72: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 22Q LOSS MUTATED | 6 | 21 | 18 |
| 22Q LOSS WILD-TYPE | 64 | 17 | 24 |
Figure S363. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00013
Table S364. Gene #72: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 22Q LOSS MUTATED | 6 | 19 | 20 |
| 22Q LOSS WILD-TYPE | 63 | 17 | 25 |
Figure S364. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00021
Table S365. Gene #72: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 22Q LOSS MUTATED | 4 | 2 | 21 | 18 |
| 22Q LOSS WILD-TYPE | 33 | 31 | 17 | 24 |
Figure S365. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00196 (Fisher's exact test), Q value = 0.009
Table S366. Gene #73: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XP LOSS MUTATED | 2 | 11 | 16 |
| XP LOSS WILD-TYPE | 46 | 33 | 42 |
Figure S366. Get High-res Image Gene #73: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00184 (Fisher's exact test), Q value = 0.0086
Table S367. Gene #73: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XP LOSS MUTATED | 6 | 6 | 17 |
| XP LOSS WILD-TYPE | 50 | 43 | 28 |
Figure S367. Get High-res Image Gene #73: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00367 (Fisher's exact test), Q value = 0.014
Table S368. Gene #73: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XP LOSS MUTATED | 2 | 9 | 4 | 14 |
| XP LOSS WILD-TYPE | 35 | 24 | 34 | 28 |
Figure S368. Get High-res Image Gene #73: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00039 (Fisher's exact test), Q value = 0.0025
Table S369. Gene #74: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XQ LOSS MUTATED | 1 | 11 | 17 |
| XQ LOSS WILD-TYPE | 47 | 33 | 41 |
Figure S369. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00198 (Fisher's exact test), Q value = 0.009
Table S370. Gene #74: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XQ LOSS MUTATED | 6 | 6 | 17 |
| XQ LOSS WILD-TYPE | 50 | 43 | 28 |
Figure S370. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0251 (Fisher's exact test), Q value = 0.058
Table S371. Gene #74: 'xq loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| XQ LOSS MUTATED | 7 | 8 | 14 |
| XQ LOSS WILD-TYPE | 45 | 49 | 27 |
Figure S371. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0258 (Fisher's exact test), Q value = 0.059
Table S372. Gene #74: 'xq loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| XQ LOSS MUTATED | 11 | 4 | 14 |
| XQ LOSS WILD-TYPE | 59 | 34 | 28 |
Figure S372. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00384 (Fisher's exact test), Q value = 0.014
Table S373. Gene #74: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XQ LOSS MUTATED | 2 | 9 | 4 | 14 |
| XQ LOSS WILD-TYPE | 35 | 24 | 34 | 28 |
Figure S373. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
-
Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
-
Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/TGCT-TP/15101914/transformed.cor.cli.txt
-
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/TGCT-TP/15111345/TGCT-TP.transferedmergedcluster.txt
-
Number of patients = 150
-
Number of significantly arm-level cnvs = 74
-
Number of molecular subtypes = 10
-
Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.