Clinical Features CN_CNMF METHLYATION_CNMF MRNASEQ_CNMF MRNASEQ_CHIERARCHICAL MIRSEQ_CNMF MIRSEQ_CHIERARCHICAL MIRSEQ_MATURE_CNMF MIRSEQ_MATURE_CHIERARCHICAL nMutated (%) nWild-Type Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q Fisher's exact test_P Fisher's exact test_Q TP53 62 (31%) 136 0.0068199 0.0614 0.77471 0.905 9.9999e-06 0.000288 0.02046 0.105 0.01968 0.105 0.00053999 0.00864 0.23219 0.495 0.01147 0.0787 CTNNB1 51 (26%) 147 0.03771 0.165 0.00086999 0.0114 9.9999e-06 0.000288 9.9999e-06 0.000288 0.0465 0.186 9.9999e-06 0.000288 0.00038 0.00684 9.9999e-06 0.000288 RB1 15 (8%) 183 0.72665 0.877 0.00080999 0.0114 0.0060899 0.0585 0.30979 0.531 0.21317 0.48 0.39024 0.624 0.21322 0.48 0.3026 0.525 AXIN1 9 (5%) 189 0.27893 0.515 0.47552 0.711 0.01082 0.0779 0.18572 0.438 0.00457 0.0506 0.45695 0.7 0.0052699 0.0542 0.69319 0.876 BAP1 10 (5%) 188 0.70641 0.877 0.0074999 0.0635 0.00128 0.0154 0.00036 0.00684 5e-05 0.0012 0.01065 0.0779 0.03912 0.166 0.01808 0.105 TSC2 9 (5%) 189 0.90661 0.953 0.01894 0.105 0.10245 0.316 0.01941 0.105 0.76373 0.901 0.56669 0.785 0.78802 0.905 0.1096 0.316 ARID1A 16 (8%) 182 0.83143 0.907 0.29001 0.516 0.066999 0.254 0.02513 0.117 0.1087 0.316 0.67085 0.863 0.01605 0.105 0.58505 0.795 IL6ST 7 (4%) 191 0.49086 0.714 0.29696 0.521 0.17009 0.419 0.13744 0.373 0.4412 0.691 0.10736 0.316 0.47901 0.711 1 1 ALB 18 (9%) 180 0.04125 0.17 0.02179 0.105 0.40758 0.645 0.57457 0.788 0.82375 0.905 0.84349 0.913 0.50518 0.724 0.25345 0.501 HNF1A 8 (4%) 190 0.16161 0.41 0.66626 0.863 0.070459 0.254 0.52584 0.742 0.094439 0.316 0.15154 0.399 0.01054 0.0779 0.28741 0.516 APOB 24 (12%) 174 1 1 0.89154 0.944 0.13216 0.369 0.10012 0.316 0.27594 0.515 0.069279 0.254 0.21855 0.484 0.02009 0.105 EEF1A1 5 (3%) 193 0.055459 0.216 0.73624 0.877 0.25399 0.501 0.13329 0.369 0.61102 0.818 0.26116 0.505 0.24062 0.495 0.61746 0.818 KIF19 10 (5%) 188 0.91766 0.958 0.10351 0.316 0.23445 0.495 0.23844 0.495 0.38332 0.62 0.81034 0.905 0.15234 0.399 0.10043 0.316 GNAS 7 (4%) 191 0.89047 0.944 0.23814 0.495 0.0293 0.132 0.17156 0.419 0.078069 0.274 0.44967 0.696 0.55547 0.777 0.72487 0.877 F5 4 (2%) 194 0.81706 0.905 0.18015 0.432 0.79825 0.905 0.61932 0.818 0.10186 0.316 0.93642 0.963 NA NA NA NA PTEN 7 (4%) 191 0.48998 0.714 0.26299 0.505 0.37177 0.615 0.5078 0.724 0.85982 0.924 0.27473 0.515 0.78285 0.905 0.28461 0.516 HIST1H1C 5 (3%) 193 0.72172 0.877 0.73658 0.877 0.47123 0.711 0.34667 0.58 0.80107 0.905 0.24733 0.501 0.6411 0.839 0.02122 0.105 DLK2 4 (2%) 194 0.81783 0.905 0.69277 0.876 0.73521 0.877 0.37887 0.62 0.33314 0.564 0.93569 0.963 0.18866 0.438 0.16234 0.41