PARADIGM pathway analysis of mRNASeq expression data
Rectum Adenocarcinoma (Primary solid tumor)
02 April 2015  |  analyses__2015_04_02
Maintainer Information
Citation Information
Maintained by TCGA GDAC Team (Broad Institute/MD Anderson Cancer Center/Harvard Medical School)
Cite as Broad Institute TCGA Genome Data Analysis Center (2015): PARADIGM pathway analysis of mRNASeq expression data. Broad Institute of MIT and Harvard. doi:10.7908/C1DR2TKP
- Overview
+ Introduction
- Summary

There were 23 significant pathways identified in this analysis.

Table 1.  Get Full Table Top 10 out of 131 pathways in order of significance.

Pathway.Name Avg.Num.Perturbations
Syndecan-1-mediated signaling events 68
TCGA08_retinoblastoma 32
Reelin signaling pathway 22
Glypican 1 network 21
FOXA2 and FOXA3 transcription factor networks 19
Syndecan-4-mediated signaling events 19
Osteopontin-mediated events 17
Caspase cascade in apoptosis 16
IL4-mediated signaling events 15
Signaling events mediated by the Hedgehog family 13
- Results
+ Summary Table
+ Inferred Pathway Levels Matrix
+ Methods & Data