		Clinical Features	Time to Death		YEARS_TO_BIRTH		PATHOLOGIC_STAGE		PATHOLOGY_T_STAGE		PATHOLOGY_N_STAGE		PATHOLOGY_M_STAGE		GENDER		RADIATION_THERAPY		KARNOFSKY_PERFORMANCE_SCORE		NUMBER_PACK_YEARS_SMOKED		NUMBER_OF_LYMPH_NODES		RACE		ETHNICITY	
	nMutated (%)	nWild-Type	logrank test_P	logrank test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Wilcoxon-test_P	Wilcoxon-test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
TP53	196 (50%)	199	0.89793	1	0.50506	1	0.11048	0.933	0.57723	1	0.0089299	0.781	0.53082	1	1	1	0.34818	1	0.29824	1	0.68031	1	0.10175	0.933	0.00161	0.572	1	1
RB1	70 (18%)	325	0.14621	1	0.089164	0.904	0.81082	1	0.44177	1	0.093389	0.904	0.63885	1	0.45156	1	0.75173	1	0.076678	0.887	0.074384	0.87	0.2901	1	0.45262	1	1	1
ELF3	46 (12%)	349	0.57226	1	0.0039871	0.781	0.95456	1	0.413	1	0.98685	1	1	1	0.28345	1	1	1	0.71767	1	0.82146	1	0.92456	1	1	1	0.6029	1
TSC1	33 (8%)	362	0.57713	1	0.2812	1	0.64907	1	0.32144	1	0.63468	1	0.25892	1	1	1	0.3848	1	0.54211	1	0.2593	1	0.48686	1	0.80235	1	0.50199	1
PIK3CA	86 (22%)	309	0.52649	1	0.62893	1	0.64345	1	0.20654	1	0.2011	1	0.4625	1	1	1	0.26594	1	0.49498	1	0.18321	1	0.017677	0.781	0.19932	1	0.67901	1
RHOB	26 (7%)	369	0.79633	1	0.0611	0.867	0.71465	1	1	1	0.063849	0.867	0.55946	1	1	1	1	1	0.321	1	0.45134	1	0.77212	1	0.29024	1	1	1
KDM6A	103 (26%)	292	0.49795	1	0.71014	1	0.45835	1	0.70695	1	0.35596	1	0.74406	1	0.8967	1	0.42435	1	0.35324	1	0.1481	1	0.025053	0.781	0.97082	1	0.68568	1
CDKN2A	26 (7%)	369	0.68388	1	0.73482	1	0.37498	1	0.71517	1	1	1	0.50284	1	0.64273	1	1	1	0.86084	1	0.14324	1	0.54546	1	0.91374	1	1	1
ARID1A	97 (25%)	298	0.33687	1	0.38842	1	0.59518	1	0.56398	1	0.36143	1	0.73274	1	0.22903	1	0.42583	1	0.33395	1	0.35107	1	0.7001	1	0.00163	0.572	0.43171	1
STAG2	56 (14%)	339	0.1949	1	0.37597	1	0.10414	0.933	0.38904	1	0.3639	1	0.02292	0.781	0.51047	1	0.73517	1	0.20908	1	0.22541	1	0.16713	1	0.04914	0.849	0.60793	1
ZFP36L1	25 (6%)	370	0.2773	1	0.17764	1	0.13612	1	0.48044	1	0.2936	1	0.039285	0.798	1	1	0.33492	1	0.19421	1	0.81498	1	0.0088562	0.781	1	1	1	1
CDKN1A	35 (9%)	360	0.52997	1	0.95162	1	0.7489	1	0.19139	1	0.54807	1	1	1	0.31101	1	0.67508	1	0.0094132	0.781	0.68881	1	0.47728	1	0.02359	0.781	0.52567	1
EP300	61 (15%)	334	0.063954	0.867	0.2506	1	0.87669	1	0.44477	1	0.33136	1	0.69399	1	0.87473	1	0.33178	1	0.86627	1	0.28809	1	0.65858	1	0.18937	1	1	1
MLL2	114 (29%)	281	0.36964	1	0.089357	0.904	0.50682	1	0.92288	1	0.41876	1	0.30647	1	0.79996	1	0.60576	1	0.755	1	0.58378	1	0.068621	0.867	0.34969	1	1	1
FGFR3	56 (14%)	339	0.15293	1	0.10124	0.933	0.02031	0.781	0.00306	0.781	0.10952	0.933	0.24776	1	0.032874	0.781	0.49978	1	0.051377	0.849	0.1228	0.948	0.54074	1	0.02353	0.781	0.60664	1
ERCC2	38 (10%)	357	0.093564	0.904	0.020092	0.781	0.50394	1	0.94592	1	1	1	1	1	0.56234	1	0.23767	1	0.019203	0.781	0.22501	1	0.3924	1	0.72581	1	0.17495	1
CREBBP	48 (12%)	347	0.4892	1	0.89129	1	0.956	1	0.38406	1	0.68229	1	0.66307	1	0.15861	1	0.71073	1	0.97366	1	0.83043	1	0.47873	1	1	1	0.60395	1
HRAS	17 (4%)	378	0.36919	1	0.32377	1	0.38992	1	0.10669	0.933	0.687	1	0.43968	1	0.15819	1	0.55462	1	0.3523	1	0.42332	1	0.87257	1	0.04439	0.849	1	1
FOXA1	14 (4%)	381	0.69905	1	0.839	1	0.12335	0.948	0.36693	1	0.089069	0.904	0.080231	0.899	0.76237	1	0.52944	1	0.071535	0.867	0.030495	0.781	0.02052	0.781	0.69642	1	1	1
KRAS	13 (3%)	382	0.0009427	0.572	0.48937	1	0.42242	1	0.34107	1	0.01337	0.781	1	1	0.19787	1	0.47496	1	0.54623	1	0.11772	0.933	0.31992	1	0.29642	1	1	1
RHOA	18 (5%)	377	0.51956	1	0.45687	1	0.13846	1	0.47773	1	0.40603	1	0.064348	0.867	0.42212	1	1	1	NA	NA	0.0056228	0.781	0.8055	1	0.88565	1	0.28892	1
KIAA1267	24 (6%)	371	0.16502	1	0.12963	0.982	0.66919	1	0.48152	1	0.91533	1	0.55946	1	0.34559	1	0.33492	1	0.96599	1	0.33635	1	0.82019	1	0.33607	1	0.39662	1
MLL	44 (11%)	351	0.88579	1	0.013183	0.781	0.54414	1	0.50249	1	0.8208	1	0.6038	1	0.46711	1	0.70777	1	0.23217	1	0.66897	1	0.27706	1	0.84057	1	0.60589	1
FAT1	50 (13%)	345	0.49168	1	0.020582	0.781	0.19106	1	0.64802	1	0.16627	1	0.32443	1	0.039393	0.798	0.72401	1	0.11521	0.933	0.047811	0.849	0.024298	0.781	0.75774	1	0.29496	1
KLF5	23 (6%)	372	0.48033	1	0.6063	1	0.93382	1	0.16775	1	0.75278	1	1	1	0.32906	1	1	1	0.093342	0.904	0.33889	1	0.77067	1	0.17668	1	1	1
PTEN	14 (4%)	381	0.57212	1	0.67654	1	0.8994	1	0.19932	1	0.56815	1	1	1	0.53376	1	1	1	0.90993	1	0.34524	1	0.60451	1	1	1	1	1
C3ORF70	17 (4%)	378	0.072335	0.867	0.07767	0.889	0.40419	1	0.22821	1	0.30762	1	0.43968	1	1	1	1	1	0.321	1	0.5525	1	0.014733	0.781	0.37073	1	1	1
PSIP1	20 (5%)	375	0.6531	1	0.12223	0.948	0.27111	1	0.11519	0.933	0.29093	1	0.53193	1	0.30702	1	0.23528	1	0.60343	1	0.22168	1	0.19268	1	0.19733	1	1	1
MLL3	74 (19%)	321	0.52713	1	0.86725	1	0.4592	1	0.33562	1	0.8759	1	0.25499	1	0.039205	0.798	0.54622	1	0.12958	0.982	0.42692	1	0.80074	1	0.46323	1	0.3607	1
ASXL2	36 (9%)	359	0.64131	1	0.5787	1	0.71441	1	0.64108	1	0.34652	1	1	1	1	1	0.38788	1	0.63309	1	0.62999	1	0.43488	1	0.70483	1	1	1
ZBTB7B	11 (3%)	384	0.1417	1	0.37966	1	0.81369	1	0.74469	1	0.82183	1	1	1	0.48481	1	1	1	0.37982	1	0.64038	1	0.135	1	0.02764	0.781	1	1
RXRA	24 (6%)	371	0.98023	1	0.10481	0.933	0.43663	1	0.40323	1	0.76796	1	0.53193	1	0.80985	1	1	1	0.15017	1	0.50061	1	0.5137	1	0.25526	1	0.38217	1
FBXW7	30 (8%)	365	0.34216	1	0.087955	0.904	0.31396	1	0.34893	1	0.26627	1	0.32443	1	0.19161	1	0.64648	1	0.72532	1	0.95188	1	0.27522	1	0.63685	1	1	1
RBM10	22 (6%)	373	0.73839	1	0.52345	1	0.46917	1	0.58358	1	0.10297	0.933	1	1	1	1	0.61257	1	0.93988	1	0.47292	1	0.13754	1	0.88859	1	1	1
NFE2L2	24 (6%)	371	0.33783	1	0.72306	1	0.14816	1	0.062419	0.867	0.83397	1	0.11528	0.933	0.029156	0.781	1	1	0.6858	1	0.67716	1	0.4657	1	0.071619	0.867	1	1
CUL1	19 (5%)	376	0.87547	1	0.57911	1	0.7274	1	0.77924	1	0.32084	1	1	1	0.79102	1	1	1	0.41752	1	0.1697	1	0.47982	1	0.8804	1	0.33698	1
HLA-A	5 (1%)	390	0.48745	1	0.87745	1	0.39459	1	0.03413	0.781	0.68712	1	1	1	1	1	1	1	NA	NA	NA	NA	0.87687	1	1	1	1	1
GNA13	12 (3%)	383	0.51778	1	0.61369	1	0.63868	1	0.63757	1	0.71527	1	1	1	0.31146	1	1	1	0.071535	0.867	0.71688	1	0.19497	1	0.55628	1	0.22012	1
NUDT11	7 (2%)	388	0.82381	1	0.13999	1	1	1	0.51176	1	0.73445	1	1	1	0.19785	1	1	1	NA	NA	NA	NA	0.98546	1	1	1	1	1
MBD1	12 (3%)	383	0.54365	1	0.59929	1	0.16179	1	1	1	0.13216	0.994	1	1	0.31146	1	1	1	0.040879	0.812	0.43742	1	0.092357	0.904	0.40296	1	1	1
SCARF2	8 (2%)	387	0.27327	1	0.14408	1	0.35527	1	1	1	0.47279	1	1	1	0.43082	1	1	1	0.96954	1	0.6461	1	0.44392	1	0.75726	1	1	1
FOXQ1	14 (4%)	381	0.27961	1	0.38547	1	0.64748	1	1	1	0.34113	1	1	1	0.76237	1	1	1	NA	NA	0.070366	0.867	0.63502	1	0.71611	1	1	1
FAM47C	21 (5%)	374	0.065525	0.867	0.77436	1	0.39969	1	0.94994	1	0.01154	0.781	1	1	0.036244	0.795	0.61257	1	0.84553	1	0.98906	1	0.072426	0.867	0.89043	1	0.38217	1
METTL3	17 (4%)	378	0.069434	0.867	0.89171	1	0.37448	1	0.36086	1	0.94788	1	1	1	0.57643	1	0.57852	1	0.096389	0.923	0.24806	1	0.14527	1	0.31152	1	1	1
ZNF185	5 (1%)	390	0.98364	1	0.38006	1	0.48031	1	1	1	0.47203	1	1	1	0.33361	1	1	1	NA	NA	NA	NA	0.10727	0.933	1	1	1	1
ERBB2	48 (12%)	347	0.031818	0.781	0.26689	1	0.62471	1	0.92994	1	0.44354	1	0.60658	1	0.72625	1	0.48974	1	0.67961	1	0.91542	1	0.19083	1	0.7237	1	1	1
ATM	53 (13%)	342	0.34853	1	0.66343	1	0.74801	1	0.79787	1	0.3769	1	0.3679	1	0.24137	1	1	1	0.083396	0.904	0.21641	1	0.21637	1	0.35067	1	0.31259	1
UNC93B1	7 (2%)	388	0.31725	1	0.53648	1	0.59026	1	0.53494	1	0.34287	1	1	1	0.19785	1	1	1	NA	NA	NA	NA	0.30136	1	1	1	1	1
SF1	10 (3%)	385	0.50031	1	0.087872	0.904	0.1148	0.933	1	1	0.0179	0.781	1	1	0.070084	0.867	1	1	0.70098	1	0.3344	1	0.057465	0.867	0.61971	1	1	1
BCL2L1	4 (1%)	391	0.030312	0.781	0.74555	1	0.34405	1	0.29006	1	1	1	1	1	0.57633	1	1	1	NA	NA	NA	NA	0.9408	1	1	1	1	1
DNAH6	16 (4%)	379	0.98103	1	0.94369	1	0.21298	1	0.15628	1	0.65199	1	1	1	0.77089	1	0.52944	1	0.7474	1	0.76161	1	0.072328	0.867	0.87299	1	0.28892	1
HES1	11 (3%)	384	0.36481	1	0.051925	0.849	0.93378	1	1	1	0.65106	1	1	1	0.7358	1	1	1	NA	NA	0.16479	1	0.55933	1	0.40536	1	1	1
ERBB3	41 (10%)	354	0.46589	1	0.7405	1	0.52513	1	0.76857	1	0.48071	1	0.60658	1	0.19325	1	0.70638	1	0.074	0.87	0.74199	1	0.53206	1	0.059409	0.867	0.19144	1
TXNIP	17 (4%)	378	0.94962	1	0.2096	1	0.76712	1	0.22732	1	0.83533	1	1	1	1	1	1	1	0.19498	1	0.93343	1	0.67413	1	0.065719	0.867	0.27224	1
THRAP3	14 (4%)	381	0.43165	1	0.091429	0.904	0.20534	1	0.80412	1	0.48139	1	1	1	0.76237	1	0.52944	1	0.6857	1	0.2572	1	0.038421	0.798	0.41541	1	0.033911	0.781
SPTAN1	45 (11%)	350	0.048651	0.849	0.052581	0.849	0.41803	1	0.21918	1	0.53071	1	1	1	0.10545	0.933	1	1	0.96346	1	0.38739	1	0.32294	1	0.59763	1	0.22524	1
ARID1B	23 (6%)	372	0.88447	1	0.3589	1	0.43696	1	0.40936	1	0.29718	1	0.19472	1	1	1	0.61672	1	0.6857	1	0.051769	0.849	0.10493	0.933	0.38359	1	1	1
NRAS	7 (2%)	388	0.20186	1	0.37013	1	0.33366	1	0.45594	1	0.53884	1	1	1	0.19785	1	1	1	NA	NA	0.19348	1	0.36172	1	0.082549	0.904	1	1
RPTN	15 (4%)	380	0.9268	1	0.99077	1	0.26114	1	0.85352	1	0.098809	0.933	1	1	0.76845	1	0.55462	1	0.89519	1	0.045984	0.849	0.14497	1	0.51651	1	1	1
RAI1	21 (5%)	374	0.1181	0.933	0.76908	1	0.63284	1	1	1	0.04751	0.849	0.11528	0.933	0.30639	1	0.61418	1	0.66454	1	0.81411	1	0.14089	1	1	1	0.32129	1
TMCO4	12 (3%)	383	0.94612	1	0.8549	1	0.68399	1	0.49188	1	0.71595	1	0.47212	1	0.73855	1	1	1	0.41752	1	0.63577	1	0.72543	1	0.03327	0.781	1	1
CNOT1	21 (5%)	374	0.010848	0.781	0.39194	1	0.19403	1	0.48042	1	0.77084	1	1	1	0.30639	1	0.61418	1	0.026902	0.781	0.017651	0.781	0.21431	1	0.6279	1	0.0067432	0.781
PARD3	22 (6%)	373	0.37245	1	0.70557	1	0.58691	1	0.23554	1	0.3098	1	1	1	0.021132	0.781	0.61418	1	0.0094471	0.781	0.5709	1	0.3492	1	0.28325	1	0.078674	0.891
EZR	12 (3%)	383	0.015412	0.781	0.43213	1	0.34404	1	0.33841	1	0.52397	1	0.29098	1	0.5158	1	0.47496	1	0.321	1	0.15379	1	0.135	1	0.20091	1	1	1
MOAP1	7 (2%)	388	0.053209	0.849	0.10743	0.933	0.806	1	0.85943	1	1	1	1	1	1	1	0.27342	1	0.24635	1	0.6058	1	1	1	0.71095	1	1	1
SF3B1	24 (6%)	371	0.49775	1	0.034974	0.784	0.18321	1	0.51809	1	0.71734	1	1	1	0.15209	1	0.62008	1	0.0096827	0.781	0.94146	1	0.83857	1	0.39728	1	1	1
RUNX1	13 (3%)	382	0.57836	1	0.72867	1	0.44201	1	0.23835	1	0.71773	1	1	1	0.52834	1	0.44553	1	0.68687	1	0.9468	1	0.092157	0.904	0.48205	1	1	1
MEGF8	20 (5%)	375	0.3065	1	0.75541	1	0.50121	1	0.62748	1	0.43448	1	1	1	0.11866	0.933	0.61199	1	0.82886	1	0.028453	0.781	0.24211	1	0.53502	1	0.30527	1
CASP8	14 (4%)	381	0.22142	1	0.79072	1	0.30161	1	0.72427	1	0.60532	1	1	1	1	1	1	1	0.89519	1	0.56849	1	0.56278	1	0.83776	1	1	1
DAZAP1	6 (2%)	389	0.34759	1	0.91366	1	0.052469	0.849	0.21601	1	1	1	1	1	1	1	1	1	0.321	1	0.20626	1	0.71169	1	1	1	1	1
USP28	13 (3%)	382	0.45358	1	0.95751	1	1	1	0.92573	1	0.46328	1	0.3693	1	1	1	1	1	0.14096	1	0.53521	1	0.47847	1	0.83846	1	1	1
SETD2	27 (7%)	368	0.62834	1	0.8376	1	0.52899	1	0.80481	1	0.49528	1	1	1	0.82084	1	1	1	0.049898	0.849	0.032102	0.781	0.70005	1	0.76559	1	1	1
EME1	5 (1%)	390	0.64909	1	0.0554	0.858	0.46672	1	0.57347	1	1	1	1	1	1	1	1	1	NA	NA	NA	NA	NA	NA	0.32878	1	1	1
ADC	5 (1%)	390	0.47215	1	0.2144	1	0.46689	1	0.57764	1	1	1	1	1	1	1	1	1	0.47685	1	NA	NA	0.92527	1	0.3318	1	1	1
CNOT3	10 (3%)	385	0.11364	0.933	0.49676	1	0.9287	1	1	1	0.69221	1	0.3693	1	0.46393	1	1	1	NA	NA	0.72106	1	0.8829	1	0.24516	1	1	1
SSH3	15 (4%)	380	0.092697	0.904	0.28738	1	0.43377	1	0.15915	1	0.25583	1	1	1	0.76845	1	1	1	NA	NA	0.65595	1	0.20034	1	0.59864	1	1	1
AHR	22 (6%)	373	0.30576	1	0.95849	1	0.2056	1	0.36127	1	0.5158	1	0.47212	1	0.61587	1	1	1	0.64861	1	0.88507	1	0.97056	1	1	1	0.36742	1
EIF4A2	11 (3%)	384	0.48903	1	0.93149	1	0.62333	1	0.19973	1	0.53089	1	0.33118	1	0.3019	1	1	1	0.56685	1	0.79227	1	0.66884	1	0.7722	1	1	1
EPHA2	19 (5%)	376	0.55915	1	0.11005	0.933	0.51463	1	0.36185	1	0.01316	0.781	0.3693	1	0.055165	0.858	0.61254	1	0.53264	1	0.19384	1	0.99862	1	0.11873	0.933	1	1
OGDH	19 (5%)	376	0.30028	1	0.34143	1	0.88616	1	0.94067	1	1	1	1	1	0.42378	1	1	1	0.47601	1	0.28978	1	0.54546	1	0.28036	1	0.33698	1
POU3F1	3 (1%)	392	0.3385	1	0.69314	1	0.083189	0.904	0.57348	1	0.063459	0.867	NA	NA	1	1	1	1	NA	NA	NA	NA	0.027503	0.781	1	1	1	1
