Clinical feature	Statistical test	Significant miRs	Associated with	&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;	Associated with	
DAYS_TO_DEATH_OR_LAST_FUP	Cox regression test	N=30	shorter survival	N=30	longer survival	N=0
YEARS_TO_BIRTH	Spearman correlation test	N=30	older	N=12	younger	N=18
PATHOLOGIC_STAGE	Kruskal-Wallis test	N=30	 	 	 	 
PATHOLOGY_T_STAGE	Spearman correlation test	N=27	higher stage	N=14	lower stage	N=13
PATHOLOGY_N_STAGE	Spearman correlation test	N=26	higher stage	N=16	lower stage	N=10
PATHOLOGY_M_STAGE	Wilcoxon test	N=0	 	 	 	 
GENDER	Wilcoxon test	N=0	 	 	 	 
RADIATION_THERAPY	Wilcoxon test	N=30	yes	N=30	no	N=0
KARNOFSKY_PERFORMANCE_SCORE	Spearman correlation test	N=30	higher score	N=18	lower score	N=12
HISTOLOGICAL_TYPE	Wilcoxon test	N=30	esophagus squamous cell carcinoma	N=30	esophagus adenocarcinoma  nos	N=0
NUMBER_PACK_YEARS_SMOKED	Spearman correlation test	N=0	 	 	 	 
RESIDUAL_TUMOR	Kruskal-Wallis test	N=0	 	 	 	 
NUMBER_OF_LYMPH_NODES	Spearman correlation test	N=3	higher number_of_lymph_nodes	N=2	lower number_of_lymph_nodes	N=1
RACE	Kruskal-Wallis test	N=30	 	 	 	 
ETHNICITY	Wilcoxon test	N=0	 	 	 	 
