This pipeline computes the correlation between significant copy number variation (cnv focal) genes and molecular subtypes.
Testing the association between copy number variation 85 focal events and 10 molecular subtypes across 184 patients, 351 significant findings detected with P value < 0.05 and Q value < 0.25.
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amp_1p34.2 cnv correlated to 'RPPA_CNMF'.
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amp_1q23.3 cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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amp_1q42.3 cnv correlated to 'CN_CNMF'.
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amp_2q31.1 cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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amp_3q26.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_5p15.33 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_6p21.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_6q23.3 cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_7p11.2 cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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amp_8p23.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_8q24.21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MIRSEQ_CNMF'.
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amp_9q34.3 cnv correlated to 'CN_CNMF' and 'RPPA_CHIERARCHICAL'.
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amp_11q13.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_12p12.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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amp_13q22.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_14q21.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_15q26.1 cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_17q12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_18p11.32 cnv correlated to 'MIRSEQ_CNMF'.
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amp_18q11.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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amp_19q12 cnv correlated to 'CN_CNMF' and 'MIRSEQ_CNMF'.
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amp_xq28 cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_1p36.11 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_1p13.2 cnv correlated to 'CN_CNMF'.
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del_2q22.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_2q33.3 cnv correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_3p26.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_3p14.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_3p14.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_3q26.31 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_4p15.2 cnv correlated to 'CN_CNMF' and 'MIRSEQ_CNMF'.
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del_4q22.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_4q34.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_5q12.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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del_6p25.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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del_7q31.1 cnv correlated to 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_7q36.3 cnv correlated to 'MRNASEQ_CNMF'.
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del_8p23.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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del_8p12 cnv correlated to 'CN_CNMF'.
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del_9p23 cnv correlated to 'MRNASEQ_CHIERARCHICAL'.
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del_9p21.3 cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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del_10p15.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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del_10p11.21 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_10q21.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_10q23.31 cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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del_11p15.4 cnv correlated to 'METHLYATION_CNMF'.
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del_11q25 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_12q23.1 cnv correlated to 'METHLYATION_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_13q12.11 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_13q14.2 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_13q21.31 cnv correlated to 'CN_CNMF'.
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del_14q23.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_15q11.2 cnv correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_16p13.3 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_16q23.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_17p12 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_17q25.3 cnv correlated to 'MIRSEQ_MATURE_CNMF'.
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del_18p11.23 cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_18q12.2 cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_18q21.2 cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_18q22.3 cnv correlated to 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_19p13.3 cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_19q11 cnv correlated to 'RPPA_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_20p12.1 cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_21q11.2 cnv correlated to 'METHLYATION_CNMF' and 'MIRSEQ_CNMF'.
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del_21q21.1 cnv correlated to 'METHLYATION_CNMF'.
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del_21q22.12 cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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del_22q11.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_xp21.1 cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
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del_xp11.3 cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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del_xq21.33 cnv correlated to 'MIRSEQ_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 85 focal events and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 351 significant findings detected.
|
Clinical Features |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| del 3q26 31 | 16 (9%) | 168 |
0.00237 (0.0139) |
1e-05 (0.000173) |
0.0116 (0.0458) |
0.00991 (0.0403) |
0.00848 (0.0368) |
0.00017 (0.0017) |
0.00034 (0.00289) |
0.00039 (0.00328) |
0.00224 (0.0132) |
0.0001 (0.00104) |
| del 10p11 21 | 52 (28%) | 132 |
1e-05 (0.000173) |
4e-05 (0.000479) |
0.006 (0.0282) |
0.0295 (0.0851) |
4e-05 (0.000479) |
2e-05 (0.000293) |
1e-05 (0.000173) |
8e-05 (0.000861) |
0.00043 (0.00355) |
3e-05 (0.000386) |
| del 22q11 1 | 79 (43%) | 105 |
1e-05 (0.000173) |
1e-05 (0.000173) |
0.00041 (0.00342) |
0.00438 (0.0219) |
4e-05 (0.000479) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
| amp 3q26 2 | 128 (70%) | 56 |
1e-05 (0.000173) |
2e-05 (0.000293) |
0.085 (0.179) |
0.00048 (0.00389) |
7e-05 (0.000773) |
1e-05 (0.000173) |
3e-05 (0.000386) |
1e-05 (0.000173) |
1e-05 (0.000173) |
3e-05 (0.000386) |
| amp 11q13 3 | 104 (57%) | 80 |
1e-05 (0.000173) |
0.00354 (0.0187) |
0.0061 (0.0285) |
0.0129 (0.0498) |
0.00124 (0.00836) |
0.00117 (0.00815) |
0.00103 (0.0073) |
0.00128 (0.00857) |
0.0912 (0.188) |
0.00124 (0.00836) |
| del 2q22 1 | 59 (32%) | 125 |
1e-05 (0.000173) |
1e-05 (0.000173) |
0.136 (0.243) |
0.0027 (0.0153) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
0.00014 (0.00142) |
3e-05 (0.000386) |
| del 13q12 11 | 76 (41%) | 108 |
0.00022 (0.00208) |
0.0137 (0.0515) |
0.206 (0.328) |
0.0376 (0.0994) |
0.00378 (0.0196) |
0.0037 (0.0193) |
0.00803 (0.035) |
0.00942 (0.039) |
0.0134 (0.0508) |
0.0156 (0.0561) |
| del 16q23 1 | 84 (46%) | 100 |
1e-05 (0.000173) |
1e-05 (0.000173) |
0.0715 (0.158) |
0.0391 (0.102) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
| amp 5p15 33 | 98 (53%) | 86 |
1e-05 (0.000173) |
0.0162 (0.0579) |
0.44 (0.557) |
0.283 (0.41) |
0.00136 (0.00903) |
0.00067 (0.00522) |
0.00032 (0.00278) |
0.00432 (0.0218) |
0.0103 (0.0415) |
0.00192 (0.0119) |
| amp 8p23 1 | 52 (28%) | 132 |
3e-05 (0.000386) |
0.0022 (0.0132) |
0.792 (0.853) |
0.177 (0.291) |
0.0147 (0.0543) |
9e-05 (0.000956) |
0.00419 (0.0213) |
0.0151 (0.0554) |
0.00019 (0.00186) |
0.00179 (0.0114) |
| amp 13q22 1 | 65 (35%) | 119 |
0.00157 (0.0103) |
0.00667 (0.0303) |
0.982 (0.988) |
0.188 (0.305) |
0.0419 (0.106) |
0.00122 (0.00836) |
0.0002 (0.00193) |
0.00252 (0.0145) |
0.013 (0.0499) |
0.00029 (0.00259) |
| amp 15q26 1 | 58 (32%) | 126 |
0.00803 (0.035) |
0.073 (0.159) |
0.263 (0.391) |
0.0452 (0.113) |
0.0212 (0.0692) |
0.0152 (0.0555) |
0.00673 (0.0303) |
0.0416 (0.106) |
0.0364 (0.098) |
0.0154 (0.0558) |
| amp 17q12 | 75 (41%) | 109 |
0.00419 (0.0213) |
0.00446 (0.0222) |
0.354 (0.475) |
0.538 (0.653) |
0.0297 (0.0854) |
0.00271 (0.0153) |
0.00222 (0.0132) |
0.0192 (0.0658) |
0.0237 (0.0746) |
0.0017 (0.011) |
| amp 18q11 2 | 59 (32%) | 125 |
0.0122 (0.0477) |
0.00944 (0.039) |
0.0801 (0.171) |
0.142 (0.251) |
0.04 (0.103) |
0.00477 (0.0232) |
0.00025 (0.00228) |
0.00919 (0.0389) |
0.0154 (0.0558) |
0.00069 (0.00533) |
| del 1p36 11 | 75 (41%) | 109 |
0.0103 (0.0415) |
0.00987 (0.0403) |
0.969 (0.976) |
0.927 (0.943) |
0.00257 (0.0147) |
0.0239 (0.0746) |
0.00252 (0.0145) |
0.0229 (0.0731) |
0.0418 (0.106) |
0.0383 (0.1) |
| del 3p26 2 | 111 (60%) | 73 |
1e-05 (0.000173) |
2e-05 (0.000293) |
0.114 (0.219) |
0.0527 (0.126) |
0.00023 (0.00215) |
4e-05 (0.000479) |
0.00013 (0.00133) |
0.00019 (0.00186) |
0.0142 (0.0531) |
0.00025 (0.00228) |
| del 3p14 3 | 126 (68%) | 58 |
1e-05 (0.000173) |
1e-05 (0.000173) |
0.0534 (0.127) |
0.0606 (0.138) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
2e-05 (0.000293) |
2e-05 (0.000293) |
| del 3p14 2 | 125 (68%) | 59 |
1e-05 (0.000173) |
3e-05 (0.000386) |
0.211 (0.333) |
0.106 (0.208) |
3e-05 (0.000386) |
1e-05 (0.000173) |
1e-05 (0.000173) |
2e-05 (0.000293) |
5e-05 (0.000582) |
1e-05 (0.000173) |
| del 4q34 3 | 99 (54%) | 85 |
0.00046 (0.00376) |
0.00648 (0.0298) |
0.262 (0.391) |
0.887 (0.917) |
0.00202 (0.0123) |
0.00117 (0.00815) |
0.00073 (0.00559) |
0.00291 (0.0161) |
0.0201 (0.0671) |
0.00174 (0.0112) |
| del 13q14 2 | 74 (40%) | 110 |
0.00147 (0.00969) |
0.00457 (0.0226) |
0.338 (0.459) |
0.131 (0.238) |
0.0194 (0.0662) |
0.0208 (0.0685) |
0.0164 (0.058) |
0.0247 (0.076) |
0.0225 (0.072) |
0.0244 (0.0757) |
| del 14q23 3 | 51 (28%) | 133 |
0.00369 (0.0193) |
0.014 (0.0523) |
0.0518 (0.125) |
0.025 (0.076) |
0.00765 (0.0339) |
0.0431 (0.109) |
0.0928 (0.19) |
0.0125 (0.0487) |
0.0286 (0.0836) |
0.0024 (0.014) |
| del 16p13 3 | 65 (35%) | 119 |
2e-05 (0.000293) |
6e-05 (0.000671) |
0.376 (0.497) |
0.297 (0.423) |
0.00062 (0.00488) |
6e-05 (0.000671) |
3e-05 (0.000386) |
2e-05 (0.000293) |
1e-05 (0.000173) |
1e-05 (0.000173) |
| del 17p12 | 86 (47%) | 98 |
6e-05 (0.000671) |
1e-05 (0.000173) |
0.0999 (0.201) |
0.254 (0.383) |
2e-05 (0.000293) |
1e-05 (0.000173) |
1e-05 (0.000173) |
1e-05 (0.000173) |
0.0106 (0.0424) |
1e-05 (0.000173) |
| amp 6p21 1 | 69 (38%) | 115 |
0.00281 (0.0157) |
0.124 (0.232) |
0.182 (0.297) |
0.209 (0.331) |
0.0268 (0.0796) |
0.0312 (0.0884) |
0.00318 (0.0173) |
0.00182 (0.0115) |
0.00684 (0.0306) |
0.00119 (0.00822) |
| amp 6q23 3 | 42 (23%) | 142 |
0.0382 (0.1) |
0.0702 (0.156) |
0.00506 (0.0243) |
0.00588 (0.0278) |
0.152 (0.261) |
0.0706 (0.156) |
0.0332 (0.0918) |
0.0313 (0.0884) |
0.00933 (0.039) |
0.00659 (0.0301) |
| amp 14q21 1 | 61 (33%) | 123 |
0.00032 (0.00278) |
0.00907 (0.0385) |
0.0749 (0.161) |
0.229 (0.354) |
0.0196 (0.0662) |
0.00305 (0.0167) |
0.00349 (0.0185) |
0.00459 (0.0226) |
0.0564 (0.132) |
0.013 (0.0498) |
| del 10p15 3 | 54 (29%) | 130 |
0.00088 (0.00639) |
0.0195 (0.0662) |
0.0318 (0.0893) |
0.168 (0.281) |
0.0436 (0.11) |
0.0262 (0.0794) |
0.00622 (0.0289) |
0.0112 (0.0444) |
0.088 (0.184) |
0.06 (0.137) |
| del 18q21 2 | 119 (65%) | 65 |
0.152 (0.261) |
0.00084 (0.00632) |
0.354 (0.475) |
0.647 (0.75) |
0.00483 (0.0233) |
0.00935 (0.039) |
0.0047 (0.023) |
0.00202 (0.0123) |
0.0147 (0.0543) |
0.0005 (0.00401) |
| del xp11 3 | 74 (40%) | 110 |
0.00088 (0.00639) |
0.164 (0.276) |
0.28 (0.408) |
0.886 (0.917) |
0.009 (0.0385) |
0.0239 (0.0746) |
0.00323 (0.0175) |
0.0448 (0.112) |
0.0328 (0.0912) |
0.0179 (0.0622) |
| del 8p23 2 | 90 (49%) | 94 |
0.0001 (0.00104) |
0.0276 (0.0816) |
0.489 (0.604) |
0.0093 (0.039) |
0.072 (0.158) |
0.0485 (0.119) |
0.00989 (0.0403) |
0.109 (0.212) |
0.0372 (0.0987) |
0.149 (0.259) |
| del 18q12 2 | 111 (60%) | 73 |
0.0942 (0.193) |
0.0171 (0.0604) |
0.512 (0.624) |
0.582 (0.693) |
0.0224 (0.072) |
0.0739 (0.16) |
0.0435 (0.11) |
0.00055 (0.00437) |
0.0349 (0.0955) |
0.00021 (0.00201) |
| amp xq28 | 69 (38%) | 115 |
0.0606 (0.138) |
0.0328 (0.0912) |
0.269 (0.396) |
0.539 (0.653) |
0.0577 (0.134) |
0.0265 (0.0796) |
0.0305 (0.0867) |
0.00219 (0.0132) |
0.365 (0.486) |
0.00328 (0.0176) |
| del 4q22 1 | 105 (57%) | 79 |
0.00027 (0.00244) |
0.11 (0.214) |
0.849 (0.891) |
0.928 (0.943) |
0.00433 (0.0218) |
0.0292 (0.0847) |
0.00286 (0.0159) |
0.144 (0.253) |
0.0524 (0.126) |
0.0371 (0.0987) |
| del 11q25 | 81 (44%) | 103 |
5e-05 (0.000582) |
0.0287 (0.0836) |
0.49 (0.605) |
0.263 (0.391) |
0.159 (0.27) |
0.0497 (0.121) |
0.0595 (0.137) |
0.083 (0.176) |
0.0267 (0.0796) |
0.03 (0.0858) |
| del 18p11 23 | 60 (33%) | 124 |
0.315 (0.44) |
0.00575 (0.0273) |
0.396 (0.519) |
0.768 (0.836) |
0.0409 (0.105) |
0.0305 (0.0867) |
0.025 (0.076) |
0.137 (0.243) |
0.14 (0.248) |
0.0482 (0.119) |
| del 20p12 1 | 33 (18%) | 151 |
0.0342 (0.0942) |
0.16 (0.271) |
0.0788 (0.169) |
0.876 (0.911) |
0.0749 (0.161) |
0.00756 (0.0336) |
0.0174 (0.0609) |
0.0494 (0.12) |
0.288 (0.414) |
0.0419 (0.106) |
| amp 8q24 21 | 145 (79%) | 39 |
0.00202 (0.0123) |
0.0221 (0.0715) |
0.0172 (0.0606) |
0.0611 (0.139) |
0.0834 (0.177) |
0.115 (0.22) |
0.00674 (0.0303) |
0.0996 (0.201) |
0.353 (0.475) |
0.148 (0.259) |
| del 5q12 1 | 112 (61%) | 72 |
0.00075 (0.00569) |
0.00085 (0.00634) |
0.81 (0.861) |
0.64 (0.746) |
0.32 (0.442) |
0.498 (0.609) |
0.0215 (0.07) |
0.0238 (0.0746) |
0.434 (0.552) |
0.0574 (0.134) |
| del 10q21 1 | 46 (25%) | 138 |
0.00191 (0.0119) |
0.0218 (0.0709) |
0.404 (0.524) |
0.352 (0.474) |
0.0653 (0.147) |
0.0659 (0.148) |
0.0161 (0.0577) |
0.0567 (0.132) |
0.234 (0.36) |
0.0489 (0.12) |
| del 18q22 3 | 112 (61%) | 72 |
0.962 (0.972) |
0.0364 (0.098) |
0.873 (0.91) |
0.866 (0.904) |
0.151 (0.261) |
0.132 (0.239) |
0.211 (0.333) |
0.00785 (0.0346) |
0.0499 (0.121) |
0.00094 (0.00677) |
| del 19p13 3 | 93 (51%) | 91 |
0.00034 (0.00289) |
0.302 (0.428) |
0.278 (0.405) |
0.987 (0.992) |
0.08 (0.171) |
0.319 (0.442) |
0.036 (0.0979) |
0.0231 (0.0737) |
0.115 (0.22) |
0.00637 (0.0294) |
| del 19q11 | 48 (26%) | 136 |
0.216 (0.338) |
0.385 (0.506) |
0.0196 (0.0662) |
0.794 (0.855) |
0.315 (0.44) |
0.762 (0.832) |
0.351 (0.474) |
0.0149 (0.0547) |
0.00102 (0.00729) |
0.0266 (0.0796) |
| del xp21 1 | 69 (38%) | 115 |
0.00086 (0.00636) |
0.0363 (0.098) |
0.0371 (0.0987) |
0.658 (0.757) |
0.0125 (0.0487) |
0.193 (0.313) |
0.0559 (0.132) |
0.161 (0.273) |
0.116 (0.222) |
0.151 (0.261) |
| amp 7p11 2 | 126 (68%) | 58 |
0.332 (0.452) |
0.112 (0.216) |
0.998 (1.00) |
0.751 (0.822) |
0.0106 (0.0424) |
0.0399 (0.103) |
0.0369 (0.0987) |
0.267 (0.395) |
0.669 (0.763) |
0.128 (0.236) |
| amp 12p12 1 | 79 (43%) | 105 |
0.0336 (0.0927) |
0.127 (0.236) |
0.249 (0.377) |
0.56 (0.67) |
0.0197 (0.0663) |
0.0293 (0.0847) |
0.0631 (0.143) |
0.084 (0.178) |
0.0567 (0.132) |
0.0868 (0.182) |
| del 2q33 3 | 36 (20%) | 148 |
0.293 (0.422) |
0.0669 (0.15) |
0.126 (0.235) |
0.195 (0.316) |
0.0596 (0.137) |
0.0275 (0.0814) |
0.0135 (0.0512) |
0.0702 (0.156) |
0.0733 (0.159) |
0.0268 (0.0796) |
| del 6p25 3 | 74 (40%) | 110 |
0.0164 (0.058) |
0.0232 (0.0737) |
0.806 (0.861) |
0.43 (0.549) |
0.105 (0.207) |
0.331 (0.452) |
0.12 (0.227) |
0.0209 (0.0685) |
0.316 (0.441) |
0.0929 (0.19) |
| del 9p21 3 | 141 (77%) | 43 |
1e-05 (0.000173) |
0.237 (0.363) |
0.828 (0.873) |
0.209 (0.331) |
0.0701 (0.156) |
0.0208 (0.0685) |
0.0344 (0.0943) |
0.104 (0.206) |
0.31 (0.437) |
0.107 (0.21) |
| del 21q22 12 | 108 (59%) | 76 |
0.1 (0.201) |
0.0107 (0.0424) |
0.487 (0.602) |
0.254 (0.383) |
0.0473 (0.117) |
0.167 (0.28) |
0.0325 (0.0908) |
0.329 (0.451) |
0.0703 (0.156) |
0.201 (0.322) |
| amp 1q23 3 | 93 (51%) | 91 |
0.00179 (0.0114) |
0.124 (0.232) |
0.834 (0.877) |
0.648 (0.75) |
0.686 (0.775) |
0.807 (0.861) |
0.169 (0.283) |
0.842 (0.885) |
0.0187 (0.0642) |
0.809 (0.861) |
| amp 2q31 1 | 60 (33%) | 124 |
0.0317 (0.0893) |
0.233 (0.359) |
0.691 (0.78) |
0.232 (0.359) |
0.753 (0.824) |
0.0379 (0.0999) |
0.541 (0.653) |
0.27 (0.397) |
0.101 (0.202) |
0.659 (0.757) |
| amp 9q34 3 | 64 (35%) | 120 |
0.025 (0.076) |
0.18 (0.295) |
0.213 (0.335) |
0.025 (0.076) |
0.129 (0.236) |
0.712 (0.796) |
0.267 (0.395) |
0.112 (0.216) |
0.116 (0.222) |
0.679 (0.772) |
| amp 19q12 | 54 (29%) | 130 |
0.00418 (0.0213) |
0.155 (0.265) |
0.436 (0.554) |
0.3 (0.425) |
0.259 (0.387) |
0.118 (0.224) |
0.0384 (0.1) |
0.273 (0.4) |
0.123 (0.231) |
0.0524 (0.126) |
| del 4p15 2 | 106 (58%) | 78 |
0.00553 (0.0264) |
0.0987 (0.2) |
0.285 (0.412) |
0.941 (0.956) |
0.102 (0.203) |
0.474 (0.59) |
0.0488 (0.12) |
0.747 (0.821) |
0.264 (0.391) |
0.953 (0.965) |
| del 10q23 31 | 65 (35%) | 119 |
0.0208 (0.0685) |
0.0358 (0.0976) |
0.454 (0.573) |
0.0911 (0.188) |
0.431 (0.549) |
0.294 (0.422) |
0.118 (0.224) |
0.281 (0.408) |
0.371 (0.491) |
0.454 (0.573) |
| del 12q23 1 | 51 (28%) | 133 |
0.247 (0.376) |
0.0184 (0.0637) |
0.234 (0.36) |
0.321 (0.442) |
0.0544 (0.129) |
0.0722 (0.158) |
0.102 (0.203) |
0.132 (0.239) |
0.181 (0.297) |
0.0457 (0.114) |
| del 15q11 2 | 63 (34%) | 121 |
0.403 (0.524) |
0.159 (0.27) |
0.818 (0.865) |
0.414 (0.535) |
0.241 (0.369) |
0.244 (0.373) |
0.201 (0.322) |
0.0199 (0.0667) |
0.638 (0.744) |
0.00346 (0.0185) |
| del 21q11 2 | 107 (58%) | 77 |
0.123 (0.231) |
0.0285 (0.0836) |
0.473 (0.59) |
0.248 (0.376) |
0.202 (0.323) |
0.217 (0.339) |
0.0491 (0.12) |
0.171 (0.284) |
0.149 (0.259) |
0.0974 (0.199) |
| amp 1p34 2 | 40 (22%) | 144 |
0.328 (0.45) |
0.631 (0.737) |
0.00879 (0.0379) |
0.256 (0.384) |
0.637 (0.743) |
0.683 (0.775) |
0.746 (0.821) |
0.32 (0.442) |
0.802 (0.86) |
0.549 (0.661) |
| amp 1q42 3 | 96 (52%) | 88 |
4e-05 (0.000479) |
0.314 (0.44) |
0.899 (0.928) |
0.415 (0.536) |
0.784 (0.85) |
0.736 (0.813) |
0.299 (0.424) |
0.283 (0.41) |
0.148 (0.259) |
0.262 (0.39) |
| amp 18p11 32 | 69 (38%) | 115 |
0.059 (0.136) |
0.109 (0.212) |
0.747 (0.821) |
0.468 (0.585) |
0.135 (0.242) |
0.174 (0.289) |
0.0179 (0.0622) |
0.56 (0.67) |
0.368 (0.489) |
0.512 (0.624) |
| del 1p13 2 | 64 (35%) | 120 |
8e-05 (0.000861) |
0.0987 (0.2) |
0.484 (0.6) |
0.567 (0.677) |
0.217 (0.339) |
0.598 (0.709) |
0.758 (0.829) |
0.106 (0.209) |
0.175 (0.289) |
0.904 (0.932) |
| del 7q31 1 | 56 (30%) | 128 |
0.222 (0.346) |
0.0891 (0.185) |
0.201 (0.322) |
0.764 (0.833) |
0.0729 (0.159) |
0.458 (0.575) |
0.401 (0.523) |
0.0986 (0.2) |
0.11 (0.213) |
0.0239 (0.0746) |
| del 7q36 3 | 67 (36%) | 117 |
0.906 (0.934) |
0.712 (0.796) |
0.787 (0.85) |
0.717 (0.797) |
0.0394 (0.102) |
0.227 (0.353) |
0.362 (0.482) |
0.151 (0.261) |
0.38 (0.501) |
0.163 (0.275) |
| del 8p12 | 75 (41%) | 109 |
0.00031 (0.00274) |
0.414 (0.535) |
0.811 (0.862) |
0.483 (0.6) |
0.917 (0.939) |
0.136 (0.243) |
0.225 (0.349) |
0.804 (0.861) |
0.556 (0.668) |
0.495 (0.608) |
| del 9p23 | 108 (59%) | 76 |
0.416 (0.536) |
0.118 (0.224) |
0.367 (0.487) |
0.714 (0.796) |
0.326 (0.447) |
0.025 (0.076) |
0.425 (0.546) |
0.723 (0.802) |
0.913 (0.939) |
0.693 (0.781) |
| del 11p15 4 | 79 (43%) | 105 |
0.129 (0.236) |
0.0466 (0.116) |
0.677 (0.771) |
0.486 (0.602) |
0.26 (0.389) |
0.361 (0.482) |
0.627 (0.736) |
0.182 (0.297) |
0.807 (0.861) |
0.456 (0.573) |
| del 13q21 31 | 69 (38%) | 115 |
0.0131 (0.0499) |
0.0529 (0.126) |
0.664 (0.759) |
0.648 (0.75) |
0.175 (0.289) |
0.114 (0.22) |
0.0881 (0.184) |
0.134 (0.241) |
0.0921 (0.19) |
0.134 (0.242) |
| del 17q25 3 | 41 (22%) | 143 |
0.375 (0.496) |
0.818 (0.865) |
0.917 (0.939) |
0.664 (0.759) |
0.833 (0.877) |
1 (1.00) |
0.129 (0.236) |
0.538 (0.653) |
0.0373 (0.0987) |
0.712 (0.796) |
| del 21q21 1 | 107 (58%) | 77 |
0.125 (0.232) |
0.00901 (0.0385) |
0.392 (0.514) |
0.128 (0.236) |
0.0597 (0.137) |
0.128 (0.236) |
0.0892 (0.185) |
0.174 (0.289) |
0.0744 (0.161) |
0.0726 (0.159) |
| del xq21 33 | 40 (22%) | 144 |
0.163 (0.275) |
0.203 (0.324) |
0.151 (0.261) |
0.818 (0.865) |
0.242 (0.371) |
0.276 (0.403) |
0.104 (0.207) |
0.0284 (0.0834) |
0.151 (0.261) |
0.185 (0.301) |
| amp 2q14 2 | 60 (33%) | 124 |
0.351 (0.474) |
0.311 (0.438) |
0.312 (0.439) |
0.303 (0.428) |
0.654 (0.755) |
0.0547 (0.129) |
0.252 (0.381) |
0.208 (0.331) |
0.268 (0.395) |
0.321 (0.442) |
| amp 4q21 1 | 34 (18%) | 150 |
0.294 (0.422) |
0.7 (0.788) |
0.154 (0.263) |
0.0589 (0.136) |
0.464 (0.581) |
0.927 (0.943) |
0.954 (0.965) |
0.426 (0.546) |
0.92 (0.942) |
0.359 (0.48) |
| amp 7q21 2 | 114 (62%) | 70 |
0.474 (0.59) |
0.16 (0.271) |
0.531 (0.647) |
0.917 (0.939) |
0.663 (0.759) |
0.817 (0.865) |
0.346 (0.47) |
0.608 (0.715) |
0.771 (0.838) |
0.141 (0.249) |
| amp 8p11 21 | 85 (46%) | 99 |
0.494 (0.608) |
0.175 (0.289) |
0.704 (0.792) |
0.654 (0.755) |
0.994 (0.998) |
0.102 (0.203) |
0.388 (0.51) |
0.966 (0.974) |
0.73 (0.809) |
0.686 (0.775) |
| amp 9p13 3 | 40 (22%) | 144 |
0.0822 (0.175) |
0.105 (0.207) |
0.873 (0.91) |
0.786 (0.85) |
0.883 (0.917) |
0.684 (0.775) |
0.714 (0.796) |
0.132 (0.239) |
0.536 (0.652) |
0.549 (0.661) |
| amp 11p13 | 52 (28%) | 132 |
0.143 (0.252) |
0.455 (0.573) |
0.886 (0.917) |
0.647 (0.75) |
0.749 (0.821) |
0.33 (0.451) |
0.209 (0.331) |
0.126 (0.234) |
0.579 (0.691) |
0.254 (0.383) |
| amp 11p13 | 50 (27%) | 134 |
0.0856 (0.18) |
0.928 (0.943) |
0.662 (0.759) |
0.426 (0.546) |
0.656 (0.756) |
1 (1.00) |
0.965 (0.974) |
0.712 (0.796) |
0.786 (0.85) |
0.497 (0.609) |
| amp 12q15 | 51 (28%) | 133 |
0.136 (0.243) |
0.599 (0.709) |
0.404 (0.524) |
0.809 (0.861) |
0.296 (0.423) |
0.916 (0.939) |
0.314 (0.44) |
0.6 (0.709) |
0.298 (0.424) |
0.179 (0.294) |
| amp 19p13 2 | 32 (17%) | 152 |
0.409 (0.53) |
0.0847 (0.179) |
0.321 (0.442) |
0.418 (0.538) |
0.318 (0.442) |
0.355 (0.476) |
0.121 (0.229) |
0.398 (0.52) |
0.319 (0.442) |
0.682 (0.775) |
| del 1q44 | 17 (9%) | 167 |
0.855 (0.896) |
0.745 (0.821) |
0.0538 (0.128) |
0.307 (0.434) |
0.949 (0.962) |
0.615 (0.723) |
0.719 (0.799) |
0.644 (0.749) |
0.8 (0.86) |
0.258 (0.386) |
| del 3q11 1 | 33 (18%) | 151 |
0.59 (0.701) |
0.627 (0.736) |
0.57 (0.68) |
0.858 (0.899) |
0.35 (0.473) |
0.82 (0.866) |
0.864 (0.903) |
0.792 (0.853) |
0.887 (0.917) |
0.629 (0.737) |
| del 6q16 3 | 55 (30%) | 129 |
0.143 (0.252) |
0.437 (0.554) |
0.399 (0.521) |
0.555 (0.667) |
0.465 (0.582) |
0.604 (0.714) |
0.13 (0.237) |
0.509 (0.623) |
0.54 (0.653) |
0.283 (0.41) |
| del 6q26 | 50 (27%) | 134 |
0.273 (0.4) |
0.928 (0.943) |
0.153 (0.263) |
0.296 (0.423) |
0.596 (0.707) |
0.198 (0.319) |
0.195 (0.316) |
0.733 (0.811) |
0.773 (0.839) |
0.333 (0.453) |
| del xq11 2 | 42 (23%) | 142 |
0.495 (0.608) |
0.248 (0.376) |
0.427 (0.546) |
0.742 (0.819) |
0.453 (0.573) |
0.605 (0.714) |
0.129 (0.236) |
0.22 (0.343) |
0.201 (0.322) |
0.716 (0.797) |
P value = 0.00879 (Fisher's exact test), Q value = 0.038
Table S1. Gene #1: 'amp_1p34.2' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| AMP PEAK 1(1P34.2) MUTATED | 6 | 7 | 10 | 1 | 3 |
| AMP PEAK 1(1P34.2) WILD-TYPE | 20 | 21 | 20 | 33 | 5 |
Figure S1. Get High-res Image Gene #1: 'amp_1p34.2' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.011
Table S2. Gene #2: 'amp_1q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 2(1Q23.3) MUTATED | 37 | 12 | 44 |
| AMP PEAK 2(1Q23.3) WILD-TYPE | 28 | 32 | 31 |
Figure S2. Get High-res Image Gene #2: 'amp_1q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0187 (Fisher's exact test), Q value = 0.064
Table S3. Gene #2: 'amp_1q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 2(1Q23.3) MUTATED | 35 | 40 | 10 | 5 |
| AMP PEAK 2(1Q23.3) WILD-TYPE | 31 | 26 | 25 | 6 |
Figure S3. Get High-res Image Gene #2: 'amp_1q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00048
Table S4. Gene #3: 'amp_1q42.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 3(1Q42.3) MUTATED | 39 | 10 | 47 |
| AMP PEAK 3(1Q42.3) WILD-TYPE | 26 | 34 | 28 |
Figure S4. Get High-res Image Gene #3: 'amp_1q42.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0317 (Fisher's exact test), Q value = 0.089
Table S5. Gene #5: 'amp_2q31.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 5(2Q31.1) MUTATED | 21 | 8 | 31 |
| AMP PEAK 5(2Q31.1) WILD-TYPE | 44 | 36 | 44 |
Figure S5. Get High-res Image Gene #5: 'amp_2q31.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0379 (Fisher's exact test), Q value = 0.1
Table S6. Gene #5: 'amp_2q31.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 5(2Q31.1) MUTATED | 15 | 10 | 35 |
| AMP PEAK 5(2Q31.1) WILD-TYPE | 52 | 10 | 61 |
Figure S6. Get High-res Image Gene #5: 'amp_2q31.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S7. Gene #6: 'amp_3q26.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 6(3Q26.2) MUTATED | 40 | 14 | 74 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 25 | 30 | 1 |
Figure S7. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S8. Gene #6: 'amp_3q26.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 6(3Q26.2) MUTATED | 41 | 19 | 68 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 35 | 13 | 8 |
Figure S8. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00048 (Fisher's exact test), Q value = 0.0039
Table S9. Gene #6: 'amp_3q26.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| AMP PEAK 6(3Q26.2) MUTATED | 12 | 12 | 14 | 25 | 29 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 11 | 9 | 8 | 1 | 5 |
Figure S9. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 0.00077
Table S10. Gene #6: 'amp_3q26.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 6(3Q26.2) MUTATED | 43 | 61 | 15 | 8 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 38 | 8 | 7 | 3 |
Figure S10. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S11. Gene #6: 'amp_3q26.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 6(3Q26.2) MUTATED | 38 | 7 | 82 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 29 | 13 | 14 |
Figure S11. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S12. Gene #6: 'amp_3q26.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 6(3Q26.2) MUTATED | 44 | 75 | 8 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 40 | 12 | 4 |
Figure S12. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S13. Gene #6: 'amp_3q26.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 6(3Q26.2) MUTATED | 33 | 13 | 56 | 25 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 29 | 13 | 6 | 8 |
Figure S13. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S14. Gene #6: 'amp_3q26.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 6(3Q26.2) MUTATED | 35 | 62 | 23 | 6 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 31 | 4 | 12 | 5 |
Figure S14. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S15. Gene #6: 'amp_3q26.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 6(3Q26.2) MUTATED | 35 | 11 | 80 |
| AMP PEAK 6(3Q26.2) WILD-TYPE | 27 | 11 | 14 |
Figure S15. Get High-res Image Gene #6: 'amp_3q26.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S16. Gene #8: 'amp_5p15.33' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 8(5P15.33) MUTATED | 31 | 11 | 56 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 34 | 33 | 19 |
Figure S16. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.058
Table S17. Gene #8: 'amp_5p15.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 8(5P15.33) MUTATED | 33 | 15 | 50 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 43 | 17 | 26 |
Figure S17. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00136 (Fisher's exact test), Q value = 0.009
Table S18. Gene #8: 'amp_5p15.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 8(5P15.33) MUTATED | 32 | 49 | 12 | 5 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 49 | 20 | 10 | 6 |
Figure S18. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00067 (Fisher's exact test), Q value = 0.0052
Table S19. Gene #8: 'amp_5p15.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 8(5P15.33) MUTATED | 30 | 5 | 63 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 37 | 15 | 33 |
Figure S19. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00032 (Fisher's exact test), Q value = 0.0028
Table S20. Gene #8: 'amp_5p15.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 8(5P15.33) MUTATED | 34 | 60 | 4 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 50 | 27 | 8 |
Figure S20. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00432 (Fisher's exact test), Q value = 0.022
Table S21. Gene #8: 'amp_5p15.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 8(5P15.33) MUTATED | 24 | 11 | 40 | 23 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 38 | 15 | 22 | 10 |
Figure S21. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.041
Table S22. Gene #8: 'amp_5p15.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 8(5P15.33) MUTATED | 27 | 46 | 19 | 6 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 39 | 20 | 16 | 5 |
Figure S22. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00192 (Fisher's exact test), Q value = 0.012
Table S23. Gene #8: 'amp_5p15.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 8(5P15.33) MUTATED | 24 | 11 | 63 |
| AMP PEAK 8(5P15.33) WILD-TYPE | 38 | 11 | 31 |
Figure S23. Get High-res Image Gene #8: 'amp_5p15.33' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00281 (Fisher's exact test), Q value = 0.016
Table S24. Gene #9: 'amp_6p21.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 9(6P21.1) MUTATED | 35 | 11 | 23 |
| AMP PEAK 9(6P21.1) WILD-TYPE | 30 | 33 | 52 |
Figure S24. Get High-res Image Gene #9: 'amp_6p21.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0268 (Fisher's exact test), Q value = 0.08
Table S25. Gene #9: 'amp_6p21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 9(6P21.1) MUTATED | 39 | 21 | 8 | 1 |
| AMP PEAK 9(6P21.1) WILD-TYPE | 42 | 48 | 14 | 10 |
Figure S25. Get High-res Image Gene #9: 'amp_6p21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0312 (Fisher's exact test), Q value = 0.088
Table S26. Gene #9: 'amp_6p21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 9(6P21.1) MUTATED | 30 | 11 | 28 |
| AMP PEAK 9(6P21.1) WILD-TYPE | 37 | 9 | 68 |
Figure S26. Get High-res Image Gene #9: 'amp_6p21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00318 (Fisher's exact test), Q value = 0.017
Table S27. Gene #9: 'amp_6p21.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 9(6P21.1) MUTATED | 41 | 26 | 1 |
| AMP PEAK 9(6P21.1) WILD-TYPE | 43 | 61 | 11 |
Figure S27. Get High-res Image Gene #9: 'amp_6p21.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00182 (Fisher's exact test), Q value = 0.011
Table S28. Gene #9: 'amp_6p21.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 9(6P21.1) MUTATED | 35 | 7 | 16 | 10 |
| AMP PEAK 9(6P21.1) WILD-TYPE | 27 | 19 | 46 | 23 |
Figure S28. Get High-res Image Gene #9: 'amp_6p21.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00684 (Fisher's exact test), Q value = 0.031
Table S29. Gene #9: 'amp_6p21.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 9(6P21.1) MUTATED | 36 | 18 | 10 | 4 |
| AMP PEAK 9(6P21.1) WILD-TYPE | 30 | 48 | 25 | 7 |
Figure S29. Get High-res Image Gene #9: 'amp_6p21.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00119 (Fisher's exact test), Q value = 0.0082
Table S30. Gene #9: 'amp_6p21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 9(6P21.1) MUTATED | 35 | 7 | 26 |
| AMP PEAK 9(6P21.1) WILD-TYPE | 27 | 15 | 68 |
Figure S30. Get High-res Image Gene #9: 'amp_6p21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0382 (Fisher's exact test), Q value = 0.1
Table S31. Gene #10: 'amp_6q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 10(6Q23.3) MUTATED | 22 | 8 | 12 |
| AMP PEAK 10(6Q23.3) WILD-TYPE | 43 | 36 | 63 |
Figure S31. Get High-res Image Gene #10: 'amp_6q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00506 (Fisher's exact test), Q value = 0.024
Table S32. Gene #10: 'amp_6q23.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| AMP PEAK 10(6Q23.3) MUTATED | 9 | 10 | 3 | 2 | 2 |
| AMP PEAK 10(6Q23.3) WILD-TYPE | 17 | 18 | 27 | 32 | 6 |
Figure S32. Get High-res Image Gene #10: 'amp_6q23.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00588 (Fisher's exact test), Q value = 0.028
Table S33. Gene #10: 'amp_6q23.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| AMP PEAK 10(6Q23.3) MUTATED | 5 | 10 | 5 | 1 | 5 |
| AMP PEAK 10(6Q23.3) WILD-TYPE | 18 | 11 | 17 | 25 | 29 |
Figure S33. Get High-res Image Gene #10: 'amp_6q23.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0332 (Fisher's exact test), Q value = 0.092
Table S34. Gene #10: 'amp_6q23.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 10(6Q23.3) MUTATED | 26 | 14 | 1 |
| AMP PEAK 10(6Q23.3) WILD-TYPE | 58 | 73 | 11 |
Figure S34. Get High-res Image Gene #10: 'amp_6q23.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0313 (Fisher's exact test), Q value = 0.088
Table S35. Gene #10: 'amp_6q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 10(6Q23.3) MUTATED | 22 | 4 | 9 | 6 |
| AMP PEAK 10(6Q23.3) WILD-TYPE | 40 | 22 | 53 | 27 |
Figure S35. Get High-res Image Gene #10: 'amp_6q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00933 (Fisher's exact test), Q value = 0.039
Table S36. Gene #10: 'amp_6q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 10(6Q23.3) MUTATED | 23 | 10 | 4 | 4 |
| AMP PEAK 10(6Q23.3) WILD-TYPE | 43 | 56 | 31 | 7 |
Figure S36. Get High-res Image Gene #10: 'amp_6q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00659 (Fisher's exact test), Q value = 0.03
Table S37. Gene #10: 'amp_6q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 10(6Q23.3) MUTATED | 23 | 3 | 15 |
| AMP PEAK 10(6Q23.3) WILD-TYPE | 39 | 19 | 79 |
Figure S37. Get High-res Image Gene #10: 'amp_6q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0106 (Fisher's exact test), Q value = 0.042
Table S38. Gene #11: 'amp_7p11.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 11(7P11.2) MUTATED | 62 | 45 | 16 | 3 |
| AMP PEAK 11(7P11.2) WILD-TYPE | 19 | 24 | 6 | 8 |
Figure S38. Get High-res Image Gene #11: 'amp_7p11.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0399 (Fisher's exact test), Q value = 0.1
Table S39. Gene #11: 'amp_7p11.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 11(7P11.2) MUTATED | 48 | 18 | 60 |
| AMP PEAK 11(7P11.2) WILD-TYPE | 19 | 2 | 36 |
Figure S39. Get High-res Image Gene #11: 'amp_7p11.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0369 (Fisher's exact test), Q value = 0.099
Table S40. Gene #11: 'amp_7p11.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 11(7P11.2) MUTATED | 64 | 56 | 5 |
| AMP PEAK 11(7P11.2) WILD-TYPE | 20 | 31 | 7 |
Figure S40. Get High-res Image Gene #11: 'amp_7p11.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S41. Gene #13: 'amp_8p23.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 13(8P23.1) MUTATED | 26 | 18 | 8 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 39 | 26 | 67 |
Figure S41. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0022 (Fisher's exact test), Q value = 0.013
Table S42. Gene #13: 'amp_8p23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 13(8P23.1) MUTATED | 32 | 5 | 15 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 44 | 27 | 61 |
Figure S42. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0147 (Fisher's exact test), Q value = 0.054
Table S43. Gene #13: 'amp_8p23.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 13(8P23.1) MUTATED | 33 | 13 | 4 | 2 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 48 | 56 | 18 | 9 |
Figure S43. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00096
Table S44. Gene #13: 'amp_8p23.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 13(8P23.1) MUTATED | 32 | 2 | 18 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 35 | 18 | 78 |
Figure S44. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00419 (Fisher's exact test), Q value = 0.021
Table S45. Gene #13: 'amp_8p23.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 13(8P23.1) MUTATED | 33 | 15 | 3 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 51 | 72 | 9 |
Figure S45. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0151 (Fisher's exact test), Q value = 0.055
Table S46. Gene #13: 'amp_8p23.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 13(8P23.1) MUTATED | 25 | 9 | 10 | 7 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 37 | 17 | 52 | 26 |
Figure S46. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00019 (Fisher's exact test), Q value = 0.0019
Table S47. Gene #13: 'amp_8p23.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 13(8P23.1) MUTATED | 28 | 7 | 11 | 2 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 38 | 59 | 24 | 9 |
Figure S47. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.011
Table S48. Gene #13: 'amp_8p23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 13(8P23.1) MUTATED | 25 | 8 | 15 |
| AMP PEAK 13(8P23.1) WILD-TYPE | 37 | 14 | 79 |
Figure S48. Get High-res Image Gene #13: 'amp_8p23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00202 (Fisher's exact test), Q value = 0.012
Table S49. Gene #15: 'amp_8q24.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 15(8Q24.21) MUTATED | 56 | 26 | 63 |
| AMP PEAK 15(8Q24.21) WILD-TYPE | 9 | 18 | 12 |
Figure S49. Get High-res Image Gene #15: 'amp_8q24.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0221 (Fisher's exact test), Q value = 0.071
Table S50. Gene #15: 'amp_8q24.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 15(8Q24.21) MUTATED | 59 | 20 | 66 |
| AMP PEAK 15(8Q24.21) WILD-TYPE | 17 | 12 | 10 |
Figure S50. Get High-res Image Gene #15: 'amp_8q24.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0172 (Fisher's exact test), Q value = 0.061
Table S51. Gene #15: 'amp_8q24.21' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| AMP PEAK 15(8Q24.21) MUTATED | 21 | 22 | 21 | 33 | 5 |
| AMP PEAK 15(8Q24.21) WILD-TYPE | 5 | 6 | 9 | 1 | 3 |
Figure S51. Get High-res Image Gene #15: 'amp_8q24.21' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00674 (Fisher's exact test), Q value = 0.03
Table S52. Gene #15: 'amp_8q24.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 15(8Q24.21) MUTATED | 66 | 73 | 5 |
| AMP PEAK 15(8Q24.21) WILD-TYPE | 18 | 14 | 7 |
Figure S52. Get High-res Image Gene #15: 'amp_8q24.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.025 (Fisher's exact test), Q value = 0.076
Table S53. Gene #17: 'amp_9q34.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 17(9Q34.3) MUTATED | 25 | 8 | 31 |
| AMP PEAK 17(9Q34.3) WILD-TYPE | 40 | 36 | 44 |
Figure S53. Get High-res Image Gene #17: 'amp_9q34.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.025 (Fisher's exact test), Q value = 0.076
Table S54. Gene #17: 'amp_9q34.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| AMP PEAK 17(9Q34.3) MUTATED | 8 | 7 | 6 | 17 | 9 |
| AMP PEAK 17(9Q34.3) WILD-TYPE | 15 | 14 | 16 | 9 | 25 |
Figure S54. Get High-res Image Gene #17: 'amp_9q34.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S55. Gene #20: 'amp_11q13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 20(11Q13.3) MUTATED | 28 | 15 | 61 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 37 | 29 | 14 |
Figure S55. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00354 (Fisher's exact test), Q value = 0.019
Table S56. Gene #20: 'amp_11q13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 20(11Q13.3) MUTATED | 32 | 20 | 52 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 44 | 12 | 24 |
Figure S56. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0061 (Fisher's exact test), Q value = 0.028
Table S57. Gene #20: 'amp_11q13.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| AMP PEAK 20(11Q13.3) MUTATED | 9 | 23 | 17 | 23 | 4 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 17 | 5 | 13 | 11 | 4 |
Figure S57. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0129 (Fisher's exact test), Q value = 0.05
Table S58. Gene #20: 'amp_11q13.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| AMP PEAK 20(11Q13.3) MUTATED | 7 | 17 | 13 | 17 | 22 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 16 | 4 | 9 | 9 | 12 |
Figure S58. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00124 (Fisher's exact test), Q value = 0.0084
Table S59. Gene #20: 'amp_11q13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 20(11Q13.3) MUTATED | 35 | 50 | 14 | 4 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 46 | 19 | 8 | 7 |
Figure S59. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00117 (Fisher's exact test), Q value = 0.0082
Table S60. Gene #20: 'amp_11q13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 20(11Q13.3) MUTATED | 27 | 10 | 66 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 40 | 10 | 30 |
Figure S60. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00103 (Fisher's exact test), Q value = 0.0073
Table S61. Gene #20: 'amp_11q13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 20(11Q13.3) MUTATED | 36 | 61 | 6 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 48 | 26 | 6 |
Figure S61. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00128 (Fisher's exact test), Q value = 0.0086
Table S62. Gene #20: 'amp_11q13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 20(11Q13.3) MUTATED | 29 | 8 | 43 | 23 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 33 | 18 | 19 | 10 |
Figure S62. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00124 (Fisher's exact test), Q value = 0.0084
Table S63. Gene #20: 'amp_11q13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 20(11Q13.3) MUTATED | 30 | 7 | 65 |
| AMP PEAK 20(11Q13.3) WILD-TYPE | 32 | 15 | 29 |
Figure S63. Get High-res Image Gene #20: 'amp_11q13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0336 (Fisher's exact test), Q value = 0.093
Table S64. Gene #21: 'amp_12p12.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 21(12P12.1) MUTATED | 26 | 13 | 40 |
| AMP PEAK 21(12P12.1) WILD-TYPE | 39 | 31 | 35 |
Figure S64. Get High-res Image Gene #21: 'amp_12p12.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0197 (Fisher's exact test), Q value = 0.066
Table S65. Gene #21: 'amp_12p12.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 21(12P12.1) MUTATED | 25 | 36 | 13 | 5 |
| AMP PEAK 21(12P12.1) WILD-TYPE | 56 | 33 | 9 | 6 |
Figure S65. Get High-res Image Gene #21: 'amp_12p12.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0293 (Fisher's exact test), Q value = 0.085
Table S66. Gene #21: 'amp_12p12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 21(12P12.1) MUTATED | 21 | 8 | 50 |
| AMP PEAK 21(12P12.1) WILD-TYPE | 46 | 12 | 46 |
Figure S66. Get High-res Image Gene #21: 'amp_12p12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00157 (Fisher's exact test), Q value = 0.01
Table S67. Gene #23: 'amp_13q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 23(13Q22.1) MUTATED | 34 | 13 | 18 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 31 | 31 | 57 |
Figure S67. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00667 (Fisher's exact test), Q value = 0.03
Table S68. Gene #23: 'amp_13q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 23(13Q22.1) MUTATED | 37 | 8 | 20 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 39 | 24 | 56 |
Figure S68. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0419 (Fisher's exact test), Q value = 0.11
Table S69. Gene #23: 'amp_13q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 23(13Q22.1) MUTATED | 38 | 19 | 6 | 2 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 43 | 50 | 16 | 9 |
Figure S69. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00122 (Fisher's exact test), Q value = 0.0084
Table S70. Gene #23: 'amp_13q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 23(13Q22.1) MUTATED | 30 | 12 | 23 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 37 | 8 | 73 |
Figure S70. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-04 (Fisher's exact test), Q value = 0.0019
Table S71. Gene #23: 'amp_13q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 23(13Q22.1) MUTATED | 42 | 21 | 1 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 42 | 66 | 11 |
Figure S71. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00252 (Fisher's exact test), Q value = 0.014
Table S72. Gene #23: 'amp_13q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 23(13Q22.1) MUTATED | 31 | 12 | 14 | 7 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 31 | 14 | 48 | 26 |
Figure S72. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.013 (Fisher's exact test), Q value = 0.05
Table S73. Gene #23: 'amp_13q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 23(13Q22.1) MUTATED | 34 | 18 | 9 | 3 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 32 | 48 | 26 | 8 |
Figure S73. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0026
Table S74. Gene #23: 'amp_13q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 23(13Q22.1) MUTATED | 33 | 10 | 21 |
| AMP PEAK 23(13Q22.1) WILD-TYPE | 29 | 12 | 73 |
Figure S74. Get High-res Image Gene #23: 'amp_13q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00032 (Fisher's exact test), Q value = 0.0028
Table S75. Gene #24: 'amp_14q21.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 24(14Q21.1) MUTATED | 19 | 6 | 36 |
| AMP PEAK 24(14Q21.1) WILD-TYPE | 46 | 38 | 39 |
Figure S75. Get High-res Image Gene #24: 'amp_14q21.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00907 (Fisher's exact test), Q value = 0.039
Table S76. Gene #24: 'amp_14q21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 24(14Q21.1) MUTATED | 18 | 8 | 35 |
| AMP PEAK 24(14Q21.1) WILD-TYPE | 58 | 24 | 41 |
Figure S76. Get High-res Image Gene #24: 'amp_14q21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0196 (Fisher's exact test), Q value = 0.066
Table S77. Gene #24: 'amp_14q21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 24(14Q21.1) MUTATED | 18 | 31 | 9 | 3 |
| AMP PEAK 24(14Q21.1) WILD-TYPE | 63 | 38 | 13 | 8 |
Figure S77. Get High-res Image Gene #24: 'amp_14q21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00305 (Fisher's exact test), Q value = 0.017
Table S78. Gene #24: 'amp_14q21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 24(14Q21.1) MUTATED | 17 | 2 | 42 |
| AMP PEAK 24(14Q21.1) WILD-TYPE | 50 | 18 | 54 |
Figure S78. Get High-res Image Gene #24: 'amp_14q21.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00349 (Fisher's exact test), Q value = 0.019
Table S79. Gene #24: 'amp_14q21.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 24(14Q21.1) MUTATED | 19 | 39 | 2 |
| AMP PEAK 24(14Q21.1) WILD-TYPE | 65 | 48 | 10 |
Figure S79. Get High-res Image Gene #24: 'amp_14q21.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00459 (Fisher's exact test), Q value = 0.023
Table S80. Gene #24: 'amp_14q21.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 24(14Q21.1) MUTATED | 14 | 5 | 31 | 10 |
| AMP PEAK 24(14Q21.1) WILD-TYPE | 48 | 21 | 31 | 23 |
Figure S80. Get High-res Image Gene #24: 'amp_14q21.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.013 (Fisher's exact test), Q value = 0.05
Table S81. Gene #24: 'amp_14q21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 24(14Q21.1) MUTATED | 14 | 5 | 41 |
| AMP PEAK 24(14Q21.1) WILD-TYPE | 48 | 17 | 53 |
Figure S81. Get High-res Image Gene #24: 'amp_14q21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00803 (Fisher's exact test), Q value = 0.035
Table S82. Gene #25: 'amp_15q26.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 25(15Q26.1) MUTATED | 30 | 10 | 18 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 35 | 34 | 57 |
Figure S82. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0452 (Fisher's exact test), Q value = 0.11
Table S83. Gene #25: 'amp_15q26.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| AMP PEAK 25(15Q26.1) MUTATED | 11 | 10 | 4 | 5 | 8 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 12 | 11 | 18 | 21 | 26 |
Figure S83. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0212 (Fisher's exact test), Q value = 0.069
Table S84. Gene #25: 'amp_15q26.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 25(15Q26.1) MUTATED | 34 | 15 | 7 | 1 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 47 | 54 | 15 | 10 |
Figure S84. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0152 (Fisher's exact test), Q value = 0.056
Table S85. Gene #25: 'amp_15q26.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 25(15Q26.1) MUTATED | 27 | 9 | 21 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 40 | 11 | 75 |
Figure S85. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00673 (Fisher's exact test), Q value = 0.03
Table S86. Gene #25: 'amp_15q26.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 25(15Q26.1) MUTATED | 36 | 21 | 1 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 48 | 66 | 11 |
Figure S86. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0416 (Fisher's exact test), Q value = 0.11
Table S87. Gene #25: 'amp_15q26.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 25(15Q26.1) MUTATED | 28 | 8 | 14 | 8 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 34 | 18 | 48 | 25 |
Figure S87. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0364 (Fisher's exact test), Q value = 0.098
Table S88. Gene #25: 'amp_15q26.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 25(15Q26.1) MUTATED | 30 | 16 | 8 | 4 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 36 | 50 | 27 | 7 |
Figure S88. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0154 (Fisher's exact test), Q value = 0.056
Table S89. Gene #25: 'amp_15q26.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 25(15Q26.1) MUTATED | 28 | 8 | 22 |
| AMP PEAK 25(15Q26.1) WILD-TYPE | 34 | 14 | 72 |
Figure S89. Get High-res Image Gene #25: 'amp_15q26.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00419 (Fisher's exact test), Q value = 0.021
Table S90. Gene #26: 'amp_17q12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 26(17Q12) MUTATED | 37 | 15 | 23 |
| AMP PEAK 26(17Q12) WILD-TYPE | 28 | 29 | 52 |
Figure S90. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00446 (Fisher's exact test), Q value = 0.022
Table S91. Gene #26: 'amp_17q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 26(17Q12) MUTATED | 41 | 7 | 27 |
| AMP PEAK 26(17Q12) WILD-TYPE | 35 | 25 | 49 |
Figure S91. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0297 (Fisher's exact test), Q value = 0.085
Table S92. Gene #26: 'amp_17q12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 26(17Q12) MUTATED | 43 | 23 | 6 | 3 |
| AMP PEAK 26(17Q12) WILD-TYPE | 38 | 46 | 16 | 8 |
Figure S92. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00271 (Fisher's exact test), Q value = 0.015
Table S93. Gene #26: 'amp_17q12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 26(17Q12) MUTATED | 38 | 8 | 29 |
| AMP PEAK 26(17Q12) WILD-TYPE | 29 | 12 | 67 |
Figure S93. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00222 (Fisher's exact test), Q value = 0.013
Table S94. Gene #26: 'amp_17q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 26(17Q12) MUTATED | 45 | 27 | 2 |
| AMP PEAK 26(17Q12) WILD-TYPE | 39 | 60 | 10 |
Figure S94. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0192 (Fisher's exact test), Q value = 0.066
Table S95. Gene #26: 'amp_17q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 26(17Q12) MUTATED | 32 | 14 | 18 | 10 |
| AMP PEAK 26(17Q12) WILD-TYPE | 30 | 12 | 44 | 23 |
Figure S95. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0237 (Fisher's exact test), Q value = 0.075
Table S96. Gene #26: 'amp_17q12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 26(17Q12) MUTATED | 36 | 20 | 11 | 4 |
| AMP PEAK 26(17Q12) WILD-TYPE | 30 | 46 | 24 | 7 |
Figure S96. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0017 (Fisher's exact test), Q value = 0.011
Table S97. Gene #26: 'amp_17q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 26(17Q12) MUTATED | 32 | 13 | 26 |
| AMP PEAK 26(17Q12) WILD-TYPE | 30 | 9 | 68 |
Figure S97. Get High-res Image Gene #26: 'amp_17q12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0179 (Fisher's exact test), Q value = 0.062
Table S98. Gene #27: 'amp_18p11.32' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 27(18P11.32) MUTATED | 27 | 40 | 1 |
| AMP PEAK 27(18P11.32) WILD-TYPE | 57 | 47 | 11 |
Figure S98. Get High-res Image Gene #27: 'amp_18p11.32' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0122 (Fisher's exact test), Q value = 0.048
Table S99. Gene #28: 'amp_18q11.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 28(18Q11.2) MUTATED | 30 | 11 | 18 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 35 | 33 | 57 |
Figure S99. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00944 (Fisher's exact test), Q value = 0.039
Table S100. Gene #28: 'amp_18q11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 28(18Q11.2) MUTATED | 34 | 8 | 17 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 42 | 24 | 59 |
Figure S100. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.04 (Fisher's exact test), Q value = 0.1
Table S101. Gene #28: 'amp_18q11.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| AMP PEAK 28(18Q11.2) MUTATED | 35 | 18 | 4 | 2 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 46 | 51 | 18 | 9 |
Figure S101. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00477 (Fisher's exact test), Q value = 0.023
Table S102. Gene #28: 'amp_18q11.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 28(18Q11.2) MUTATED | 28 | 10 | 21 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 39 | 10 | 75 |
Figure S102. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0023
Table S103. Gene #28: 'amp_18q11.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 28(18Q11.2) MUTATED | 38 | 21 | 0 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 46 | 66 | 12 |
Figure S103. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00919 (Fisher's exact test), Q value = 0.039
Table S104. Gene #28: 'amp_18q11.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 28(18Q11.2) MUTATED | 28 | 11 | 14 | 6 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 34 | 15 | 48 | 27 |
Figure S104. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0154 (Fisher's exact test), Q value = 0.056
Table S105. Gene #28: 'amp_18q11.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| AMP PEAK 28(18Q11.2) MUTATED | 31 | 14 | 10 | 3 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 35 | 52 | 25 | 8 |
Figure S105. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00069 (Fisher's exact test), Q value = 0.0053
Table S106. Gene #28: 'amp_18q11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 28(18Q11.2) MUTATED | 28 | 11 | 19 |
| AMP PEAK 28(18Q11.2) WILD-TYPE | 34 | 11 | 75 |
Figure S106. Get High-res Image Gene #28: 'amp_18q11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00418 (Fisher's exact test), Q value = 0.021
Table S107. Gene #30: 'amp_19q12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| AMP PEAK 30(19Q12) MUTATED | 29 | 9 | 16 |
| AMP PEAK 30(19Q12) WILD-TYPE | 36 | 35 | 59 |
Figure S107. Get High-res Image Gene #30: 'amp_19q12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0384 (Fisher's exact test), Q value = 0.1
Table S108. Gene #30: 'amp_19q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 30(19Q12) MUTATED | 32 | 21 | 1 |
| AMP PEAK 30(19Q12) WILD-TYPE | 52 | 66 | 11 |
Figure S108. Get High-res Image Gene #30: 'amp_19q12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0328 (Fisher's exact test), Q value = 0.091
Table S109. Gene #31: 'amp_xq28' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| AMP PEAK 31(XQ28) MUTATED | 22 | 10 | 37 |
| AMP PEAK 31(XQ28) WILD-TYPE | 54 | 22 | 39 |
Figure S109. Get High-res Image Gene #31: 'amp_xq28' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0265 (Fisher's exact test), Q value = 0.08
Table S110. Gene #31: 'amp_xq28' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| AMP PEAK 31(XQ28) MUTATED | 18 | 6 | 45 |
| AMP PEAK 31(XQ28) WILD-TYPE | 49 | 14 | 51 |
Figure S110. Get High-res Image Gene #31: 'amp_xq28' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0305 (Fisher's exact test), Q value = 0.087
Table S111. Gene #31: 'amp_xq28' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| AMP PEAK 31(XQ28) MUTATED | 24 | 41 | 3 |
| AMP PEAK 31(XQ28) WILD-TYPE | 60 | 46 | 9 |
Figure S111. Get High-res Image Gene #31: 'amp_xq28' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00219 (Fisher's exact test), Q value = 0.013
Table S112. Gene #31: 'amp_xq28' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| AMP PEAK 31(XQ28) MUTATED | 22 | 2 | 29 | 15 |
| AMP PEAK 31(XQ28) WILD-TYPE | 40 | 24 | 33 | 18 |
Figure S112. Get High-res Image Gene #31: 'amp_xq28' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00328 (Fisher's exact test), Q value = 0.018
Table S113. Gene #31: 'amp_xq28' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| AMP PEAK 31(XQ28) MUTATED | 22 | 2 | 43 |
| AMP PEAK 31(XQ28) WILD-TYPE | 40 | 20 | 51 |
Figure S113. Get High-res Image Gene #31: 'amp_xq28' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.041
Table S114. Gene #32: 'del_1p36.11' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 1(1P36.11) MUTATED | 36 | 13 | 26 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 29 | 31 | 49 |
Figure S114. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00987 (Fisher's exact test), Q value = 0.04
Table S115. Gene #32: 'del_1p36.11' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 1(1P36.11) MUTATED | 41 | 9 | 25 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 35 | 23 | 51 |
Figure S115. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00257 (Fisher's exact test), Q value = 0.015
Table S116. Gene #32: 'del_1p36.11' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 1(1P36.11) MUTATED | 44 | 21 | 9 | 1 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 37 | 48 | 13 | 10 |
Figure S116. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0239 (Fisher's exact test), Q value = 0.075
Table S117. Gene #32: 'del_1p36.11' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 1(1P36.11) MUTATED | 36 | 8 | 31 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 31 | 12 | 65 |
Figure S117. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00252 (Fisher's exact test), Q value = 0.014
Table S118. Gene #32: 'del_1p36.11' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 1(1P36.11) MUTATED | 44 | 30 | 1 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 40 | 57 | 11 |
Figure S118. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0229 (Fisher's exact test), Q value = 0.073
Table S119. Gene #32: 'del_1p36.11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 1(1P36.11) MUTATED | 33 | 11 | 24 | 7 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 29 | 15 | 38 | 26 |
Figure S119. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0418 (Fisher's exact test), Q value = 0.11
Table S120. Gene #32: 'del_1p36.11' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 1(1P36.11) MUTATED | 36 | 25 | 10 | 3 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 30 | 41 | 25 | 8 |
Figure S120. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0383 (Fisher's exact test), Q value = 0.1
Table S121. Gene #32: 'del_1p36.11' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 1(1P36.11) MUTATED | 33 | 10 | 31 |
| DEL PEAK 1(1P36.11) WILD-TYPE | 29 | 12 | 63 |
Figure S121. Get High-res Image Gene #32: 'del_1p36.11' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00086
Table S122. Gene #33: 'del_1p13.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 2(1P13.2) MUTATED | 29 | 4 | 31 |
| DEL PEAK 2(1P13.2) WILD-TYPE | 36 | 40 | 44 |
Figure S122. Get High-res Image Gene #33: 'del_1p13.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S123. Gene #35: 'del_2q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 4(2Q22.1) MUTATED | 11 | 8 | 40 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 54 | 36 | 35 |
Figure S123. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S124. Gene #35: 'del_2q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 4(2Q22.1) MUTATED | 10 | 8 | 41 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 66 | 24 | 35 |
Figure S124. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0027 (Fisher's exact test), Q value = 0.015
Table S125. Gene #35: 'del_2q22.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 4(2Q22.1) MUTATED | 3 | 7 | 4 | 10 | 20 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 20 | 14 | 18 | 16 | 14 |
Figure S125. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S126. Gene #35: 'del_2q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 4(2Q22.1) MUTATED | 11 | 34 | 12 | 1 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 70 | 35 | 10 | 10 |
Figure S126. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S127. Gene #35: 'del_2q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 4(2Q22.1) MUTATED | 6 | 6 | 46 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 61 | 14 | 50 |
Figure S127. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S128. Gene #35: 'del_2q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 4(2Q22.1) MUTATED | 12 | 45 | 2 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 72 | 42 | 10 |
Figure S128. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S129. Gene #35: 'del_2q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 4(2Q22.1) MUTATED | 10 | 3 | 26 | 20 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 52 | 23 | 36 | 13 |
Figure S129. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00014 (Fisher's exact test), Q value = 0.0014
Table S130. Gene #35: 'del_2q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 4(2Q22.1) MUTATED | 11 | 35 | 10 | 3 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 55 | 31 | 25 | 8 |
Figure S130. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S131. Gene #35: 'del_2q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 4(2Q22.1) MUTATED | 10 | 3 | 46 |
| DEL PEAK 4(2Q22.1) WILD-TYPE | 52 | 19 | 48 |
Figure S131. Get High-res Image Gene #35: 'del_2q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0275 (Fisher's exact test), Q value = 0.081
Table S132. Gene #36: 'del_2q33.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 5(2Q33.3) MUTATED | 7 | 3 | 26 |
| DEL PEAK 5(2Q33.3) WILD-TYPE | 60 | 17 | 70 |
Figure S132. Get High-res Image Gene #36: 'del_2q33.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0135 (Fisher's exact test), Q value = 0.051
Table S133. Gene #36: 'del_2q33.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 5(2Q33.3) MUTATED | 9 | 22 | 4 |
| DEL PEAK 5(2Q33.3) WILD-TYPE | 75 | 65 | 8 |
Figure S133. Get High-res Image Gene #36: 'del_2q33.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0268 (Fisher's exact test), Q value = 0.08
Table S134. Gene #36: 'del_2q33.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 5(2Q33.3) MUTATED | 6 | 3 | 25 |
| DEL PEAK 5(2Q33.3) WILD-TYPE | 56 | 19 | 69 |
Figure S134. Get High-res Image Gene #36: 'del_2q33.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S135. Gene #37: 'del_3p26.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 6(3P26.2) MUTATED | 32 | 16 | 63 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 33 | 28 | 12 |
Figure S135. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S136. Gene #37: 'del_3p26.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 6(3P26.2) MUTATED | 33 | 18 | 60 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 43 | 14 | 16 |
Figure S136. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0021
Table S137. Gene #37: 'del_3p26.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 6(3P26.2) MUTATED | 38 | 55 | 11 | 6 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 43 | 14 | 11 | 5 |
Figure S137. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00048
Table S138. Gene #37: 'del_3p26.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 6(3P26.2) MUTATED | 27 | 11 | 72 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 40 | 9 | 24 |
Figure S138. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.0013
Table S139. Gene #37: 'del_3p26.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 6(3P26.2) MUTATED | 38 | 66 | 7 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 46 | 21 | 5 |
Figure S139. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.0019
Table S140. Gene #37: 'del_3p26.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 6(3P26.2) MUTATED | 29 | 10 | 48 | 24 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 33 | 16 | 14 | 9 |
Figure S140. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0142 (Fisher's exact test), Q value = 0.053
Table S141. Gene #37: 'del_3p26.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 6(3P26.2) MUTATED | 32 | 50 | 21 | 7 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 34 | 16 | 14 | 4 |
Figure S141. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00025 (Fisher's exact test), Q value = 0.0023
Table S142. Gene #37: 'del_3p26.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 6(3P26.2) MUTATED | 29 | 10 | 71 |
| DEL PEAK 6(3P26.2) WILD-TYPE | 33 | 12 | 23 |
Figure S142. Get High-res Image Gene #37: 'del_3p26.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S143. Gene #38: 'del_3p14.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 7(3P14.3) MUTATED | 37 | 18 | 71 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 28 | 26 | 4 |
Figure S143. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S144. Gene #38: 'del_3p14.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 7(3P14.3) MUTATED | 37 | 23 | 66 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 39 | 9 | 10 |
Figure S144. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S145. Gene #38: 'del_3p14.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 7(3P14.3) MUTATED | 43 | 62 | 14 | 6 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 38 | 7 | 8 | 5 |
Figure S145. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S146. Gene #38: 'del_3p14.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 7(3P14.3) MUTATED | 32 | 11 | 82 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 35 | 9 | 14 |
Figure S146. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S147. Gene #38: 'del_3p14.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 7(3P14.3) MUTATED | 43 | 76 | 7 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 41 | 11 | 5 |
Figure S147. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S148. Gene #38: 'del_3p14.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 7(3P14.3) MUTATED | 32 | 12 | 54 | 28 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 30 | 14 | 8 | 5 |
Figure S148. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S149. Gene #38: 'del_3p14.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 7(3P14.3) MUTATED | 32 | 59 | 25 | 8 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 34 | 7 | 10 | 3 |
Figure S149. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S150. Gene #38: 'del_3p14.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 7(3P14.3) MUTATED | 32 | 11 | 81 |
| DEL PEAK 7(3P14.3) WILD-TYPE | 30 | 11 | 13 |
Figure S150. Get High-res Image Gene #38: 'del_3p14.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S151. Gene #39: 'del_3p14.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 8(3P14.2) MUTATED | 38 | 17 | 70 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 27 | 27 | 5 |
Figure S151. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S152. Gene #39: 'del_3p14.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 8(3P14.2) MUTATED | 38 | 22 | 65 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 38 | 10 | 11 |
Figure S152. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S153. Gene #39: 'del_3p14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 8(3P14.2) MUTATED | 43 | 61 | 14 | 6 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 38 | 8 | 8 | 5 |
Figure S153. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S154. Gene #39: 'del_3p14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 8(3P14.2) MUTATED | 31 | 12 | 81 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 36 | 8 | 15 |
Figure S154. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S155. Gene #39: 'del_3p14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 8(3P14.2) MUTATED | 43 | 75 | 7 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 41 | 12 | 5 |
Figure S155. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S156. Gene #39: 'del_3p14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 8(3P14.2) MUTATED | 33 | 11 | 53 | 28 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 29 | 15 | 9 | 5 |
Figure S156. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 0.00058
Table S157. Gene #39: 'del_3p14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 8(3P14.2) MUTATED | 34 | 58 | 24 | 7 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 32 | 8 | 11 | 4 |
Figure S157. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S158. Gene #39: 'del_3p14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 8(3P14.2) MUTATED | 33 | 10 | 80 |
| DEL PEAK 8(3P14.2) WILD-TYPE | 29 | 12 | 14 |
Figure S158. Get High-res Image Gene #39: 'del_3p14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00237 (Fisher's exact test), Q value = 0.014
Table S159. Gene #41: 'del_3q26.31' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 10(3Q26.31) MUTATED | 11 | 4 | 1 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 54 | 40 | 74 |
Figure S159. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S160. Gene #41: 'del_3q26.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 10(3Q26.31) MUTATED | 15 | 0 | 1 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 61 | 32 | 75 |
Figure S160. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0116 (Fisher's exact test), Q value = 0.046
Table S161. Gene #41: 'del_3q26.31' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| DEL PEAK 10(3Q26.31) MUTATED | 6 | 3 | 1 | 0 | 0 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 20 | 25 | 29 | 34 | 8 |
Figure S161. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00991 (Fisher's exact test), Q value = 0.04
Table S162. Gene #41: 'del_3q26.31' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 10(3Q26.31) MUTATED | 4 | 3 | 3 | 0 | 0 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 19 | 18 | 19 | 26 | 34 |
Figure S162. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00848 (Fisher's exact test), Q value = 0.037
Table S163. Gene #41: 'del_3q26.31' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 10(3Q26.31) MUTATED | 13 | 1 | 1 | 1 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 68 | 68 | 21 | 10 |
Figure S163. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0017
Table S164. Gene #41: 'del_3q26.31' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 10(3Q26.31) MUTATED | 12 | 3 | 1 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 55 | 17 | 95 |
Figure S164. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00034 (Fisher's exact test), Q value = 0.0029
Table S165. Gene #41: 'del_3q26.31' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 10(3Q26.31) MUTATED | 15 | 1 | 0 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 69 | 86 | 12 |
Figure S165. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00039 (Fisher's exact test), Q value = 0.0033
Table S166. Gene #41: 'del_3q26.31' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 10(3Q26.31) MUTATED | 11 | 4 | 0 | 1 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 51 | 22 | 62 | 32 |
Figure S166. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00224 (Fisher's exact test), Q value = 0.013
Table S167. Gene #41: 'del_3q26.31' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 10(3Q26.31) MUTATED | 13 | 1 | 2 | 0 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 53 | 65 | 33 | 11 |
Figure S167. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.001
Table S168. Gene #41: 'del_3q26.31' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 10(3Q26.31) MUTATED | 11 | 4 | 1 |
| DEL PEAK 10(3Q26.31) WILD-TYPE | 51 | 18 | 93 |
Figure S168. Get High-res Image Gene #41: 'del_3q26.31' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00553 (Fisher's exact test), Q value = 0.026
Table S169. Gene #42: 'del_4p15.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 11(4P15.2) MUTATED | 42 | 16 | 48 |
| DEL PEAK 11(4P15.2) WILD-TYPE | 23 | 28 | 27 |
Figure S169. Get High-res Image Gene #42: 'del_4p15.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0488 (Fisher's exact test), Q value = 0.12
Table S170. Gene #42: 'del_4p15.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 11(4P15.2) MUTATED | 48 | 55 | 3 |
| DEL PEAK 11(4P15.2) WILD-TYPE | 36 | 32 | 9 |
Figure S170. Get High-res Image Gene #42: 'del_4p15.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00027 (Fisher's exact test), Q value = 0.0024
Table S171. Gene #43: 'del_4q22.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 12(4Q22.1) MUTATED | 49 | 16 | 40 |
| DEL PEAK 12(4Q22.1) WILD-TYPE | 16 | 28 | 35 |
Figure S171. Get High-res Image Gene #43: 'del_4q22.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00433 (Fisher's exact test), Q value = 0.022
Table S172. Gene #43: 'del_4q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 12(4Q22.1) MUTATED | 55 | 39 | 9 | 2 |
| DEL PEAK 12(4Q22.1) WILD-TYPE | 26 | 30 | 13 | 9 |
Figure S172. Get High-res Image Gene #43: 'del_4q22.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0292 (Fisher's exact test), Q value = 0.085
Table S173. Gene #43: 'del_4q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 12(4Q22.1) MUTATED | 47 | 10 | 48 |
| DEL PEAK 12(4Q22.1) WILD-TYPE | 20 | 10 | 48 |
Figure S173. Get High-res Image Gene #43: 'del_4q22.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00286 (Fisher's exact test), Q value = 0.016
Table S174. Gene #43: 'del_4q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 12(4Q22.1) MUTATED | 56 | 47 | 2 |
| DEL PEAK 12(4Q22.1) WILD-TYPE | 28 | 40 | 10 |
Figure S174. Get High-res Image Gene #43: 'del_4q22.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0371 (Fisher's exact test), Q value = 0.099
Table S175. Gene #43: 'del_4q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 12(4Q22.1) MUTATED | 43 | 14 | 46 |
| DEL PEAK 12(4Q22.1) WILD-TYPE | 19 | 8 | 48 |
Figure S175. Get High-res Image Gene #43: 'del_4q22.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0038
Table S176. Gene #44: 'del_4q34.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 13(4Q34.3) MUTATED | 47 | 16 | 36 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 18 | 28 | 39 |
Figure S176. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00648 (Fisher's exact test), Q value = 0.03
Table S177. Gene #44: 'del_4q34.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 13(4Q34.3) MUTATED | 51 | 12 | 36 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 25 | 20 | 40 |
Figure S177. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00202 (Fisher's exact test), Q value = 0.012
Table S178. Gene #44: 'del_4q34.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 13(4Q34.3) MUTATED | 55 | 32 | 10 | 2 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 26 | 37 | 12 | 9 |
Figure S178. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00117 (Fisher's exact test), Q value = 0.0082
Table S179. Gene #44: 'del_4q34.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 13(4Q34.3) MUTATED | 48 | 9 | 42 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 19 | 11 | 54 |
Figure S179. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00073 (Fisher's exact test), Q value = 0.0056
Table S180. Gene #44: 'del_4q34.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 13(4Q34.3) MUTATED | 56 | 41 | 2 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 28 | 46 | 10 |
Figure S180. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00291 (Fisher's exact test), Q value = 0.016
Table S181. Gene #44: 'del_4q34.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 13(4Q34.3) MUTATED | 44 | 14 | 30 | 11 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 18 | 12 | 32 | 22 |
Figure S181. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0201 (Fisher's exact test), Q value = 0.067
Table S182. Gene #44: 'del_4q34.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 13(4Q34.3) MUTATED | 44 | 31 | 14 | 8 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 22 | 35 | 21 | 3 |
Figure S182. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00174 (Fisher's exact test), Q value = 0.011
Table S183. Gene #44: 'del_4q34.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 13(4Q34.3) MUTATED | 44 | 13 | 40 |
| DEL PEAK 13(4Q34.3) WILD-TYPE | 18 | 9 | 54 |
Figure S183. Get High-res Image Gene #44: 'del_4q34.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00075 (Fisher's exact test), Q value = 0.0057
Table S184. Gene #45: 'del_5q12.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 14(5Q12.1) MUTATED | 49 | 17 | 46 |
| DEL PEAK 14(5Q12.1) WILD-TYPE | 16 | 27 | 29 |
Figure S184. Get High-res Image Gene #45: 'del_5q12.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00085 (Fisher's exact test), Q value = 0.0063
Table S185. Gene #45: 'del_5q12.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 14(5Q12.1) MUTATED | 53 | 10 | 49 |
| DEL PEAK 14(5Q12.1) WILD-TYPE | 23 | 22 | 27 |
Figure S185. Get High-res Image Gene #45: 'del_5q12.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0215 (Fisher's exact test), Q value = 0.07
Table S186. Gene #45: 'del_5q12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 14(5Q12.1) MUTATED | 56 | 52 | 3 |
| DEL PEAK 14(5Q12.1) WILD-TYPE | 28 | 35 | 9 |
Figure S186. Get High-res Image Gene #45: 'del_5q12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0238 (Fisher's exact test), Q value = 0.075
Table S187. Gene #45: 'del_5q12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 14(5Q12.1) MUTATED | 46 | 12 | 32 | 21 |
| DEL PEAK 14(5Q12.1) WILD-TYPE | 16 | 14 | 30 | 12 |
Figure S187. Get High-res Image Gene #45: 'del_5q12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0164 (Fisher's exact test), Q value = 0.058
Table S188. Gene #46: 'del_6p25.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 15(6P25.3) MUTATED | 34 | 11 | 29 |
| DEL PEAK 15(6P25.3) WILD-TYPE | 31 | 33 | 46 |
Figure S188. Get High-res Image Gene #46: 'del_6p25.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0232 (Fisher's exact test), Q value = 0.074
Table S189. Gene #46: 'del_6p25.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 15(6P25.3) MUTATED | 38 | 7 | 29 |
| DEL PEAK 15(6P25.3) WILD-TYPE | 38 | 25 | 47 |
Figure S189. Get High-res Image Gene #46: 'del_6p25.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0209 (Fisher's exact test), Q value = 0.069
Table S190. Gene #46: 'del_6p25.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 15(6P25.3) MUTATED | 31 | 10 | 26 | 6 |
| DEL PEAK 15(6P25.3) WILD-TYPE | 31 | 16 | 36 | 27 |
Figure S190. Get High-res Image Gene #46: 'del_6p25.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0239 (Fisher's exact test), Q value = 0.075
Table S191. Gene #49: 'del_7q31.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 18(7Q31.1) MUTATED | 27 | 4 | 24 |
| DEL PEAK 18(7Q31.1) WILD-TYPE | 35 | 18 | 70 |
Figure S191. Get High-res Image Gene #49: 'del_7q31.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0394 (Fisher's exact test), Q value = 0.1
Table S192. Gene #50: 'del_7q36.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 19(7Q36.3) MUTATED | 32 | 28 | 7 | 0 |
| DEL PEAK 19(7Q36.3) WILD-TYPE | 49 | 41 | 15 | 11 |
Figure S192. Get High-res Image Gene #50: 'del_7q36.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.001
Table S193. Gene #51: 'del_8p23.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 20(8P23.2) MUTATED | 30 | 11 | 49 |
| DEL PEAK 20(8P23.2) WILD-TYPE | 35 | 33 | 26 |
Figure S193. Get High-res Image Gene #51: 'del_8p23.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0276 (Fisher's exact test), Q value = 0.082
Table S194. Gene #51: 'del_8p23.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 20(8P23.2) MUTATED | 32 | 12 | 46 |
| DEL PEAK 20(8P23.2) WILD-TYPE | 44 | 20 | 30 |
Figure S194. Get High-res Image Gene #51: 'del_8p23.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0093 (Fisher's exact test), Q value = 0.039
Table S195. Gene #51: 'del_8p23.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 20(8P23.2) MUTATED | 5 | 8 | 14 | 14 | 22 |
| DEL PEAK 20(8P23.2) WILD-TYPE | 18 | 13 | 8 | 12 | 12 |
Figure S195. Get High-res Image Gene #51: 'del_8p23.2' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0485 (Fisher's exact test), Q value = 0.12
Table S196. Gene #51: 'del_8p23.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 20(8P23.2) MUTATED | 27 | 7 | 55 |
| DEL PEAK 20(8P23.2) WILD-TYPE | 40 | 13 | 41 |
Figure S196. Get High-res Image Gene #51: 'del_8p23.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00989 (Fisher's exact test), Q value = 0.04
Table S197. Gene #51: 'del_8p23.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 20(8P23.2) MUTATED | 33 | 53 | 4 |
| DEL PEAK 20(8P23.2) WILD-TYPE | 51 | 34 | 8 |
Figure S197. Get High-res Image Gene #51: 'del_8p23.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0372 (Fisher's exact test), Q value = 0.099
Table S198. Gene #51: 'del_8p23.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 20(8P23.2) MUTATED | 25 | 41 | 15 | 5 |
| DEL PEAK 20(8P23.2) WILD-TYPE | 41 | 25 | 20 | 6 |
Figure S198. Get High-res Image Gene #51: 'del_8p23.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0027
Table S199. Gene #52: 'del_8p12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 21(8P12) MUTATED | 29 | 7 | 39 |
| DEL PEAK 21(8P12) WILD-TYPE | 36 | 37 | 36 |
Figure S199. Get High-res Image Gene #52: 'del_8p12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.025 (Fisher's exact test), Q value = 0.076
Table S200. Gene #53: 'del_9p23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 22(9P23) MUTATED | 46 | 7 | 54 |
| DEL PEAK 22(9P23) WILD-TYPE | 21 | 13 | 42 |
Figure S200. Get High-res Image Gene #53: 'del_9p23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S201. Gene #54: 'del_9p21.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 23(9P21.3) MUTATED | 46 | 25 | 70 |
| DEL PEAK 23(9P21.3) WILD-TYPE | 19 | 19 | 5 |
Figure S201. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0208 (Fisher's exact test), Q value = 0.069
Table S202. Gene #54: 'del_9p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 23(9P21.3) MUTATED | 49 | 11 | 80 |
| DEL PEAK 23(9P21.3) WILD-TYPE | 18 | 9 | 16 |
Figure S202. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0344 (Fisher's exact test), Q value = 0.094
Table S203. Gene #54: 'del_9p21.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 23(9P21.3) MUTATED | 59 | 74 | 8 |
| DEL PEAK 23(9P21.3) WILD-TYPE | 25 | 13 | 4 |
Figure S203. Get High-res Image Gene #54: 'del_9p21.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00088 (Fisher's exact test), Q value = 0.0064
Table S204. Gene #55: 'del_10p15.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 24(10P15.3) MUTATED | 15 | 6 | 33 |
| DEL PEAK 24(10P15.3) WILD-TYPE | 50 | 38 | 42 |
Figure S204. Get High-res Image Gene #55: 'del_10p15.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0195 (Fisher's exact test), Q value = 0.066
Table S205. Gene #55: 'del_10p15.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 24(10P15.3) MUTATED | 14 | 13 | 27 |
| DEL PEAK 24(10P15.3) WILD-TYPE | 62 | 19 | 49 |
Figure S205. Get High-res Image Gene #55: 'del_10p15.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0318 (Fisher's exact test), Q value = 0.089
Table S206. Gene #55: 'del_10p15.3' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| DEL PEAK 24(10P15.3) MUTATED | 4 | 7 | 16 | 13 | 2 |
| DEL PEAK 24(10P15.3) WILD-TYPE | 22 | 21 | 14 | 21 | 6 |
Figure S206. Get High-res Image Gene #55: 'del_10p15.3' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0436 (Fisher's exact test), Q value = 0.11
Table S207. Gene #55: 'del_10p15.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 24(10P15.3) MUTATED | 16 | 28 | 7 | 3 |
| DEL PEAK 24(10P15.3) WILD-TYPE | 65 | 41 | 15 | 8 |
Figure S207. Get High-res Image Gene #55: 'del_10p15.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0262 (Fisher's exact test), Q value = 0.079
Table S208. Gene #55: 'del_10p15.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 24(10P15.3) MUTATED | 12 | 6 | 36 |
| DEL PEAK 24(10P15.3) WILD-TYPE | 55 | 14 | 60 |
Figure S208. Get High-res Image Gene #55: 'del_10p15.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00622 (Fisher's exact test), Q value = 0.029
Table S209. Gene #55: 'del_10p15.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 24(10P15.3) MUTATED | 18 | 35 | 1 |
| DEL PEAK 24(10P15.3) WILD-TYPE | 66 | 52 | 11 |
Figure S209. Get High-res Image Gene #55: 'del_10p15.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0112 (Fisher's exact test), Q value = 0.044
Table S210. Gene #55: 'del_10p15.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 24(10P15.3) MUTATED | 12 | 7 | 28 | 7 |
| DEL PEAK 24(10P15.3) WILD-TYPE | 50 | 19 | 34 | 26 |
Figure S210. Get High-res Image Gene #55: 'del_10p15.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S211. Gene #56: 'del_10p11.21' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 25(10P11.21) MUTATED | 9 | 5 | 38 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 56 | 39 | 37 |
Figure S211. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #1: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00048
Table S212. Gene #56: 'del_10p11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 25(10P11.21) MUTATED | 9 | 10 | 33 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 67 | 22 | 43 |
Figure S212. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.006 (Fisher's exact test), Q value = 0.028
Table S213. Gene #56: 'del_10p11.21' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| DEL PEAK 25(10P11.21) MUTATED | 2 | 8 | 12 | 17 | 3 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 24 | 20 | 18 | 17 | 5 |
Figure S213. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0295 (Fisher's exact test), Q value = 0.085
Table S214. Gene #56: 'del_10p11.21' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 25(10P11.21) MUTATED | 2 | 7 | 7 | 13 | 13 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 21 | 14 | 15 | 13 | 21 |
Figure S214. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00048
Table S215. Gene #56: 'del_10p11.21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 25(10P11.21) MUTATED | 9 | 29 | 10 | 3 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 72 | 40 | 12 | 8 |
Figure S215. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S216. Gene #56: 'del_10p11.21' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 25(10P11.21) MUTATED | 7 | 3 | 41 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 60 | 17 | 55 |
Figure S216. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S217. Gene #56: 'del_10p11.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 25(10P11.21) MUTATED | 10 | 40 | 1 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 74 | 47 | 11 |
Figure S217. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00086
Table S218. Gene #56: 'del_10p11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 25(10P11.21) MUTATED | 7 | 3 | 27 | 14 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 55 | 23 | 35 | 19 |
Figure S218. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00043 (Fisher's exact test), Q value = 0.0035
Table S219. Gene #56: 'del_10p11.21' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 25(10P11.21) MUTATED | 8 | 29 | 10 | 4 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 58 | 37 | 25 | 7 |
Figure S219. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S220. Gene #56: 'del_10p11.21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 25(10P11.21) MUTATED | 7 | 3 | 41 |
| DEL PEAK 25(10P11.21) WILD-TYPE | 55 | 19 | 53 |
Figure S220. Get High-res Image Gene #56: 'del_10p11.21' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00191 (Fisher's exact test), Q value = 0.012
Table S221. Gene #57: 'del_10q21.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 26(10Q21.1) MUTATED | 11 | 6 | 29 |
| DEL PEAK 26(10Q21.1) WILD-TYPE | 54 | 38 | 46 |
Figure S221. Get High-res Image Gene #57: 'del_10q21.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0218 (Fisher's exact test), Q value = 0.071
Table S222. Gene #57: 'del_10q21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 26(10Q21.1) MUTATED | 12 | 7 | 27 |
| DEL PEAK 26(10Q21.1) WILD-TYPE | 64 | 25 | 49 |
Figure S222. Get High-res Image Gene #57: 'del_10q21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0161 (Fisher's exact test), Q value = 0.058
Table S223. Gene #57: 'del_10q21.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 26(10Q21.1) MUTATED | 15 | 30 | 1 |
| DEL PEAK 26(10Q21.1) WILD-TYPE | 69 | 57 | 11 |
Figure S223. Get High-res Image Gene #57: 'del_10q21.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0489 (Fisher's exact test), Q value = 0.12
Table S224. Gene #57: 'del_10q21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 26(10Q21.1) MUTATED | 10 | 4 | 31 |
| DEL PEAK 26(10Q21.1) WILD-TYPE | 52 | 18 | 63 |
Figure S224. Get High-res Image Gene #57: 'del_10q21.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0208 (Fisher's exact test), Q value = 0.069
Table S225. Gene #58: 'del_10q23.31' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 27(10Q23.31) MUTATED | 22 | 9 | 34 |
| DEL PEAK 27(10Q23.31) WILD-TYPE | 43 | 35 | 41 |
Figure S225. Get High-res Image Gene #58: 'del_10q23.31' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0358 (Fisher's exact test), Q value = 0.098
Table S226. Gene #58: 'del_10q23.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 27(10Q23.31) MUTATED | 20 | 10 | 35 |
| DEL PEAK 27(10Q23.31) WILD-TYPE | 56 | 22 | 41 |
Figure S226. Get High-res Image Gene #58: 'del_10q23.31' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0466 (Fisher's exact test), Q value = 0.12
Table S227. Gene #59: 'del_11p15.4' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 28(11P15.4) MUTATED | 30 | 9 | 40 |
| DEL PEAK 28(11P15.4) WILD-TYPE | 46 | 23 | 36 |
Figure S227. Get High-res Image Gene #59: 'del_11p15.4' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00058
Table S228. Gene #60: 'del_11q25' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 29(11Q25) MUTATED | 24 | 9 | 48 |
| DEL PEAK 29(11Q25) WILD-TYPE | 41 | 35 | 27 |
Figure S228. Get High-res Image Gene #60: 'del_11q25' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0287 (Fisher's exact test), Q value = 0.084
Table S229. Gene #60: 'del_11q25' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 29(11Q25) MUTATED | 29 | 10 | 42 |
| DEL PEAK 29(11Q25) WILD-TYPE | 47 | 22 | 34 |
Figure S229. Get High-res Image Gene #60: 'del_11q25' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0497 (Fisher's exact test), Q value = 0.12
Table S230. Gene #60: 'del_11q25' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 29(11Q25) MUTATED | 22 | 8 | 50 |
| DEL PEAK 29(11Q25) WILD-TYPE | 45 | 12 | 46 |
Figure S230. Get High-res Image Gene #60: 'del_11q25' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0267 (Fisher's exact test), Q value = 0.08
Table S231. Gene #60: 'del_11q25' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 29(11Q25) MUTATED | 23 | 37 | 16 | 2 |
| DEL PEAK 29(11Q25) WILD-TYPE | 43 | 29 | 19 | 9 |
Figure S231. Get High-res Image Gene #60: 'del_11q25' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.03 (Fisher's exact test), Q value = 0.086
Table S232. Gene #60: 'del_11q25' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 29(11Q25) MUTATED | 19 | 10 | 49 |
| DEL PEAK 29(11Q25) WILD-TYPE | 43 | 12 | 45 |
Figure S232. Get High-res Image Gene #60: 'del_11q25' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0184 (Fisher's exact test), Q value = 0.064
Table S233. Gene #61: 'del_12q23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 30(12Q23.1) MUTATED | 28 | 10 | 13 |
| DEL PEAK 30(12Q23.1) WILD-TYPE | 48 | 22 | 63 |
Figure S233. Get High-res Image Gene #61: 'del_12q23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0457 (Fisher's exact test), Q value = 0.11
Table S234. Gene #61: 'del_12q23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 30(12Q23.1) MUTATED | 20 | 10 | 20 |
| DEL PEAK 30(12Q23.1) WILD-TYPE | 42 | 12 | 74 |
Figure S234. Get High-res Image Gene #61: 'del_12q23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00022 (Fisher's exact test), Q value = 0.0021
Table S235. Gene #62: 'del_13q12.11' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 31(13Q12.11) MUTATED | 24 | 9 | 43 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 41 | 35 | 32 |
Figure S235. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.051
Table S236. Gene #62: 'del_13q12.11' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 31(13Q12.11) MUTATED | 24 | 11 | 41 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 52 | 21 | 35 |
Figure S236. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0376 (Fisher's exact test), Q value = 0.099
Table S237. Gene #62: 'del_13q12.11' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 31(13Q12.11) MUTATED | 7 | 5 | 9 | 17 | 16 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 16 | 16 | 13 | 9 | 18 |
Figure S237. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00378 (Fisher's exact test), Q value = 0.02
Table S238. Gene #62: 'del_13q12.11' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 31(13Q12.11) MUTATED | 25 | 40 | 6 | 4 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 56 | 29 | 16 | 7 |
Figure S238. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0037 (Fisher's exact test), Q value = 0.019
Table S239. Gene #62: 'del_13q12.11' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 31(13Q12.11) MUTATED | 23 | 3 | 49 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 44 | 17 | 47 |
Figure S239. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00803 (Fisher's exact test), Q value = 0.035
Table S240. Gene #62: 'del_13q12.11' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 31(13Q12.11) MUTATED | 25 | 46 | 5 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 59 | 41 | 7 |
Figure S240. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00942 (Fisher's exact test), Q value = 0.039
Table S241. Gene #62: 'del_13q12.11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 31(13Q12.11) MUTATED | 19 | 7 | 30 | 20 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 43 | 19 | 32 | 13 |
Figure S241. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0134 (Fisher's exact test), Q value = 0.051
Table S242. Gene #62: 'del_13q12.11' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 31(13Q12.11) MUTATED | 20 | 37 | 11 | 5 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 46 | 29 | 24 | 6 |
Figure S242. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0156 (Fisher's exact test), Q value = 0.056
Table S243. Gene #62: 'del_13q12.11' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 31(13Q12.11) MUTATED | 18 | 7 | 48 |
| DEL PEAK 31(13Q12.11) WILD-TYPE | 44 | 15 | 46 |
Figure S243. Get High-res Image Gene #62: 'del_13q12.11' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00147 (Fisher's exact test), Q value = 0.0097
Table S244. Gene #63: 'del_13q14.2' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 32(13Q14.2) MUTATED | 23 | 10 | 41 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 42 | 34 | 34 |
Figure S244. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00457 (Fisher's exact test), Q value = 0.023
Table S245. Gene #63: 'del_13q14.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 32(13Q14.2) MUTATED | 25 | 8 | 41 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 51 | 24 | 35 |
Figure S245. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.066
Table S246. Gene #63: 'del_13q14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 32(13Q14.2) MUTATED | 25 | 38 | 7 | 4 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 56 | 31 | 15 | 7 |
Figure S246. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0208 (Fisher's exact test), Q value = 0.069
Table S247. Gene #63: 'del_13q14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 32(13Q14.2) MUTATED | 21 | 5 | 48 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 46 | 15 | 48 |
Figure S247. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0164 (Fisher's exact test), Q value = 0.058
Table S248. Gene #63: 'del_13q14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 32(13Q14.2) MUTATED | 25 | 44 | 4 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 59 | 43 | 8 |
Figure S248. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0247 (Fisher's exact test), Q value = 0.076
Table S249. Gene #63: 'del_13q14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 32(13Q14.2) MUTATED | 21 | 5 | 31 | 16 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 41 | 21 | 31 | 17 |
Figure S249. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0225 (Fisher's exact test), Q value = 0.072
Table S250. Gene #63: 'del_13q14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 32(13Q14.2) MUTATED | 21 | 36 | 10 | 4 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 45 | 30 | 25 | 7 |
Figure S250. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0244 (Fisher's exact test), Q value = 0.076
Table S251. Gene #63: 'del_13q14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 32(13Q14.2) MUTATED | 20 | 5 | 46 |
| DEL PEAK 32(13Q14.2) WILD-TYPE | 42 | 17 | 48 |
Figure S251. Get High-res Image Gene #63: 'del_13q14.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0131 (Fisher's exact test), Q value = 0.05
Table S252. Gene #64: 'del_13q21.31' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 33(13Q21.31) MUTATED | 22 | 10 | 37 |
| DEL PEAK 33(13Q21.31) WILD-TYPE | 43 | 34 | 38 |
Figure S252. Get High-res Image Gene #64: 'del_13q21.31' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00369 (Fisher's exact test), Q value = 0.019
Table S253. Gene #65: 'del_14q23.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 34(14Q23.3) MUTATED | 28 | 8 | 15 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 37 | 36 | 60 |
Figure S253. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.014 (Fisher's exact test), Q value = 0.052
Table S254. Gene #65: 'del_14q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 34(14Q23.3) MUTATED | 29 | 9 | 13 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 47 | 23 | 63 |
Figure S254. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.025 (Fisher's exact test), Q value = 0.076
Table S255. Gene #65: 'del_14q23.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 34(14Q23.3) MUTATED | 6 | 11 | 7 | 6 | 4 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 17 | 10 | 15 | 20 | 30 |
Figure S255. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00765 (Fisher's exact test), Q value = 0.034
Table S256. Gene #65: 'del_14q23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 34(14Q23.3) MUTATED | 31 | 17 | 1 | 2 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 50 | 52 | 21 | 9 |
Figure S256. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0431 (Fisher's exact test), Q value = 0.11
Table S257. Gene #65: 'del_14q23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 34(14Q23.3) MUTATED | 26 | 5 | 20 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 41 | 15 | 76 |
Figure S257. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0125 (Fisher's exact test), Q value = 0.049
Table S258. Gene #65: 'del_14q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 34(14Q23.3) MUTATED | 27 | 5 | 13 | 6 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 35 | 21 | 49 | 27 |
Figure S258. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0286 (Fisher's exact test), Q value = 0.084
Table S259. Gene #65: 'del_14q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 34(14Q23.3) MUTATED | 27 | 16 | 5 | 3 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 39 | 50 | 30 | 8 |
Figure S259. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0024 (Fisher's exact test), Q value = 0.014
Table S260. Gene #65: 'del_14q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 34(14Q23.3) MUTATED | 28 | 4 | 19 |
| DEL PEAK 34(14Q23.3) WILD-TYPE | 34 | 18 | 75 |
Figure S260. Get High-res Image Gene #65: 'del_14q23.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0199 (Fisher's exact test), Q value = 0.067
Table S261. Gene #66: 'del_15q11.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 35(15Q11.2) MUTATED | 19 | 16 | 20 | 8 |
| DEL PEAK 35(15Q11.2) WILD-TYPE | 43 | 10 | 42 | 25 |
Figure S261. Get High-res Image Gene #66: 'del_15q11.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00346 (Fisher's exact test), Q value = 0.018
Table S262. Gene #66: 'del_15q11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 35(15Q11.2) MUTATED | 20 | 15 | 28 |
| DEL PEAK 35(15Q11.2) WILD-TYPE | 42 | 7 | 66 |
Figure S262. Get High-res Image Gene #66: 'del_15q11.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S263. Gene #67: 'del_16p13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 36(16P13.3) MUTATED | 39 | 10 | 16 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 26 | 34 | 59 |
Figure S263. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00067
Table S264. Gene #67: 'del_16p13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 36(16P13.3) MUTATED | 41 | 8 | 16 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 35 | 24 | 60 |
Figure S264. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00062 (Fisher's exact test), Q value = 0.0049
Table S265. Gene #67: 'del_16p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 36(16P13.3) MUTATED | 42 | 15 | 6 | 2 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 39 | 54 | 16 | 9 |
Figure S265. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00067
Table S266. Gene #67: 'del_16p13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 36(16P13.3) MUTATED | 34 | 11 | 20 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 33 | 9 | 76 |
Figure S266. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00039
Table S267. Gene #67: 'del_16p13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 36(16P13.3) MUTATED | 44 | 18 | 2 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 40 | 69 | 10 |
Figure S267. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S268. Gene #67: 'del_16p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 36(16P13.3) MUTATED | 37 | 9 | 14 | 4 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 25 | 17 | 48 | 29 |
Figure S268. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S269. Gene #67: 'del_16p13.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 36(16P13.3) MUTATED | 38 | 13 | 9 | 3 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 28 | 53 | 26 | 8 |
Figure S269. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S270. Gene #67: 'del_16p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 36(16P13.3) MUTATED | 36 | 9 | 18 |
| DEL PEAK 36(16P13.3) WILD-TYPE | 26 | 13 | 76 |
Figure S270. Get High-res Image Gene #67: 'del_16p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S271. Gene #68: 'del_16q23.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 37(16Q23.1) MUTATED | 50 | 18 | 16 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 15 | 26 | 59 |
Figure S271. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S272. Gene #68: 'del_16q23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 37(16Q23.1) MUTATED | 56 | 11 | 17 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 20 | 21 | 59 |
Figure S272. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0391 (Fisher's exact test), Q value = 0.1
Table S273. Gene #68: 'del_16q23.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 37(16Q23.1) MUTATED | 11 | 13 | 11 | 7 | 9 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 12 | 8 | 11 | 19 | 25 |
Figure S273. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S274. Gene #68: 'del_16q23.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 37(16Q23.1) MUTATED | 57 | 18 | 7 | 2 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 24 | 51 | 15 | 9 |
Figure S274. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S275. Gene #68: 'del_16q23.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 37(16Q23.1) MUTATED | 49 | 12 | 23 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 18 | 8 | 73 |
Figure S275. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S276. Gene #68: 'del_16q23.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 37(16Q23.1) MUTATED | 60 | 22 | 1 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 24 | 65 | 11 |
Figure S276. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S277. Gene #68: 'del_16q23.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 37(16Q23.1) MUTATED | 46 | 16 | 14 | 7 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 16 | 10 | 48 | 26 |
Figure S277. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S278. Gene #68: 'del_16q23.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 37(16Q23.1) MUTATED | 49 | 17 | 11 | 4 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 17 | 49 | 24 | 7 |
Figure S278. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S279. Gene #68: 'del_16q23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 37(16Q23.1) MUTATED | 46 | 14 | 21 |
| DEL PEAK 37(16Q23.1) WILD-TYPE | 16 | 8 | 73 |
Figure S279. Get High-res Image Gene #68: 'del_16q23.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00067
Table S280. Gene #69: 'del_17p12' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 38(17P12) MUTATED | 44 | 19 | 23 |
| DEL PEAK 38(17P12) WILD-TYPE | 21 | 25 | 52 |
Figure S280. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S281. Gene #69: 'del_17p12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 38(17P12) MUTATED | 54 | 10 | 22 |
| DEL PEAK 38(17P12) WILD-TYPE | 22 | 22 | 54 |
Figure S281. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00029
Table S282. Gene #69: 'del_17p12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 38(17P12) MUTATED | 55 | 21 | 7 | 3 |
| DEL PEAK 38(17P12) WILD-TYPE | 26 | 48 | 15 | 8 |
Figure S282. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S283. Gene #69: 'del_17p12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 38(17P12) MUTATED | 46 | 11 | 29 |
| DEL PEAK 38(17P12) WILD-TYPE | 21 | 9 | 67 |
Figure S283. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S284. Gene #69: 'del_17p12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 38(17P12) MUTATED | 56 | 29 | 1 |
| DEL PEAK 38(17P12) WILD-TYPE | 28 | 58 | 11 |
Figure S284. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S285. Gene #69: 'del_17p12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 38(17P12) MUTATED | 41 | 17 | 19 | 9 |
| DEL PEAK 38(17P12) WILD-TYPE | 21 | 9 | 43 | 24 |
Figure S285. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0106 (Fisher's exact test), Q value = 0.042
Table S286. Gene #69: 'del_17p12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 38(17P12) MUTATED | 42 | 26 | 12 | 5 |
| DEL PEAK 38(17P12) WILD-TYPE | 24 | 40 | 23 | 6 |
Figure S286. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S287. Gene #69: 'del_17p12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 38(17P12) MUTATED | 41 | 16 | 28 |
| DEL PEAK 38(17P12) WILD-TYPE | 21 | 6 | 66 |
Figure S287. Get High-res Image Gene #69: 'del_17p12' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0373 (Fisher's exact test), Q value = 0.099
Table S288. Gene #70: 'del_17q25.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 39(17Q25.3) MUTATED | 14 | 21 | 3 | 1 |
| DEL PEAK 39(17Q25.3) WILD-TYPE | 52 | 45 | 32 | 10 |
Figure S288. Get High-res Image Gene #70: 'del_17q25.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00575 (Fisher's exact test), Q value = 0.027
Table S289. Gene #71: 'del_18p11.23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 40(18P11.23) MUTATED | 35 | 7 | 18 |
| DEL PEAK 40(18P11.23) WILD-TYPE | 41 | 25 | 58 |
Figure S289. Get High-res Image Gene #71: 'del_18p11.23' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0409 (Fisher's exact test), Q value = 0.11
Table S290. Gene #71: 'del_18p11.23' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 40(18P11.23) MUTATED | 35 | 17 | 4 | 3 |
| DEL PEAK 40(18P11.23) WILD-TYPE | 46 | 52 | 18 | 8 |
Figure S290. Get High-res Image Gene #71: 'del_18p11.23' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0305 (Fisher's exact test), Q value = 0.087
Table S291. Gene #71: 'del_18p11.23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 40(18P11.23) MUTATED | 29 | 7 | 23 |
| DEL PEAK 40(18P11.23) WILD-TYPE | 38 | 13 | 73 |
Figure S291. Get High-res Image Gene #71: 'del_18p11.23' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.025 (Fisher's exact test), Q value = 0.076
Table S292. Gene #71: 'del_18p11.23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 40(18P11.23) MUTATED | 35 | 20 | 5 |
| DEL PEAK 40(18P11.23) WILD-TYPE | 49 | 67 | 7 |
Figure S292. Get High-res Image Gene #71: 'del_18p11.23' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0482 (Fisher's exact test), Q value = 0.12
Table S293. Gene #71: 'del_18p11.23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 40(18P11.23) MUTATED | 26 | 9 | 23 |
| DEL PEAK 40(18P11.23) WILD-TYPE | 36 | 13 | 71 |
Figure S293. Get High-res Image Gene #71: 'del_18p11.23' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0171 (Fisher's exact test), Q value = 0.06
Table S294. Gene #72: 'del_18q12.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 41(18Q12.2) MUTATED | 55 | 16 | 40 |
| DEL PEAK 41(18Q12.2) WILD-TYPE | 21 | 16 | 36 |
Figure S294. Get High-res Image Gene #72: 'del_18q12.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0224 (Fisher's exact test), Q value = 0.072
Table S295. Gene #72: 'del_18q12.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 41(18Q12.2) MUTATED | 57 | 38 | 8 | 7 |
| DEL PEAK 41(18Q12.2) WILD-TYPE | 24 | 31 | 14 | 4 |
Figure S295. Get High-res Image Gene #72: 'del_18q12.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0435 (Fisher's exact test), Q value = 0.11
Table S296. Gene #72: 'del_18q12.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 41(18Q12.2) MUTATED | 59 | 45 | 7 |
| DEL PEAK 41(18Q12.2) WILD-TYPE | 25 | 42 | 5 |
Figure S296. Get High-res Image Gene #72: 'del_18q12.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00055 (Fisher's exact test), Q value = 0.0044
Table S297. Gene #72: 'del_18q12.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 41(18Q12.2) MUTATED | 38 | 23 | 38 | 12 |
| DEL PEAK 41(18Q12.2) WILD-TYPE | 24 | 3 | 24 | 21 |
Figure S297. Get High-res Image Gene #72: 'del_18q12.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0349 (Fisher's exact test), Q value = 0.096
Table S298. Gene #72: 'del_18q12.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 41(18Q12.2) MUTATED | 45 | 32 | 26 | 6 |
| DEL PEAK 41(18Q12.2) WILD-TYPE | 21 | 34 | 9 | 5 |
Figure S298. Get High-res Image Gene #72: 'del_18q12.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.002
Table S299. Gene #72: 'del_18q12.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 41(18Q12.2) MUTATED | 39 | 21 | 49 |
| DEL PEAK 41(18Q12.2) WILD-TYPE | 23 | 1 | 45 |
Figure S299. Get High-res Image Gene #72: 'del_18q12.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00084 (Fisher's exact test), Q value = 0.0063
Table S300. Gene #73: 'del_18q21.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 42(18Q21.2) MUTATED | 61 | 17 | 41 |
| DEL PEAK 42(18Q21.2) WILD-TYPE | 15 | 15 | 35 |
Figure S300. Get High-res Image Gene #73: 'del_18q21.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00483 (Fisher's exact test), Q value = 0.023
Table S301. Gene #73: 'del_18q21.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 42(18Q21.2) MUTATED | 63 | 38 | 10 | 7 |
| DEL PEAK 42(18Q21.2) WILD-TYPE | 18 | 31 | 12 | 4 |
Figure S301. Get High-res Image Gene #73: 'del_18q21.2' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00935 (Fisher's exact test), Q value = 0.039
Table S302. Gene #73: 'del_18q21.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 42(18Q21.2) MUTATED | 51 | 15 | 52 |
| DEL PEAK 42(18Q21.2) WILD-TYPE | 16 | 5 | 44 |
Figure S302. Get High-res Image Gene #73: 'del_18q21.2' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0047 (Fisher's exact test), Q value = 0.023
Table S303. Gene #73: 'del_18q21.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 42(18Q21.2) MUTATED | 65 | 47 | 7 |
| DEL PEAK 42(18Q21.2) WILD-TYPE | 19 | 40 | 5 |
Figure S303. Get High-res Image Gene #73: 'del_18q21.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00202 (Fisher's exact test), Q value = 0.012
Table S304. Gene #73: 'del_18q21.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 42(18Q21.2) MUTATED | 43 | 23 | 39 | 14 |
| DEL PEAK 42(18Q21.2) WILD-TYPE | 19 | 3 | 23 | 19 |
Figure S304. Get High-res Image Gene #73: 'del_18q21.2' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0147 (Fisher's exact test), Q value = 0.054
Table S305. Gene #73: 'del_18q21.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 42(18Q21.2) MUTATED | 49 | 33 | 26 | 8 |
| DEL PEAK 42(18Q21.2) WILD-TYPE | 17 | 33 | 9 | 3 |
Figure S305. Get High-res Image Gene #73: 'del_18q21.2' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 5e-04 (Fisher's exact test), Q value = 0.004
Table S306. Gene #73: 'del_18q21.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 42(18Q21.2) MUTATED | 43 | 21 | 52 |
| DEL PEAK 42(18Q21.2) WILD-TYPE | 19 | 1 | 42 |
Figure S306. Get High-res Image Gene #73: 'del_18q21.2' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0364 (Fisher's exact test), Q value = 0.098
Table S307. Gene #74: 'del_18q22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 43(18Q22.3) MUTATED | 54 | 15 | 43 |
| DEL PEAK 43(18Q22.3) WILD-TYPE | 22 | 17 | 33 |
Figure S307. Get High-res Image Gene #74: 'del_18q22.3' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00785 (Fisher's exact test), Q value = 0.035
Table S308. Gene #74: 'del_18q22.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 43(18Q22.3) MUTATED | 35 | 23 | 38 | 16 |
| DEL PEAK 43(18Q22.3) WILD-TYPE | 27 | 3 | 24 | 17 |
Figure S308. Get High-res Image Gene #74: 'del_18q22.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0499 (Fisher's exact test), Q value = 0.12
Table S309. Gene #74: 'del_18q22.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 43(18Q22.3) MUTATED | 41 | 33 | 26 | 9 |
| DEL PEAK 43(18Q22.3) WILD-TYPE | 25 | 33 | 9 | 2 |
Figure S309. Get High-res Image Gene #74: 'del_18q22.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00094 (Fisher's exact test), Q value = 0.0068
Table S310. Gene #74: 'del_18q22.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 43(18Q22.3) MUTATED | 35 | 21 | 53 |
| DEL PEAK 43(18Q22.3) WILD-TYPE | 27 | 1 | 41 |
Figure S310. Get High-res Image Gene #74: 'del_18q22.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00034 (Fisher's exact test), Q value = 0.0029
Table S311. Gene #75: 'del_19p13.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 44(19P13.3) MUTATED | 43 | 12 | 38 |
| DEL PEAK 44(19P13.3) WILD-TYPE | 22 | 32 | 37 |
Figure S311. Get High-res Image Gene #75: 'del_19p13.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.036 (Fisher's exact test), Q value = 0.098
Table S312. Gene #75: 'del_19p13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 44(19P13.3) MUTATED | 47 | 44 | 2 |
| DEL PEAK 44(19P13.3) WILD-TYPE | 37 | 43 | 10 |
Figure S312. Get High-res Image Gene #75: 'del_19p13.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0231 (Fisher's exact test), Q value = 0.074
Table S313. Gene #75: 'del_19p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 44(19P13.3) MUTATED | 40 | 9 | 26 | 18 |
| DEL PEAK 44(19P13.3) WILD-TYPE | 22 | 17 | 36 | 15 |
Figure S313. Get High-res Image Gene #75: 'del_19p13.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00637 (Fisher's exact test), Q value = 0.029
Table S314. Gene #75: 'del_19p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 44(19P13.3) MUTATED | 41 | 7 | 43 |
| DEL PEAK 44(19P13.3) WILD-TYPE | 21 | 15 | 51 |
Figure S314. Get High-res Image Gene #75: 'del_19p13.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0196 (Fisher's exact test), Q value = 0.066
Table S315. Gene #76: 'del_19q11' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| DEL PEAK 45(19Q11) MUTATED | 10 | 6 | 2 | 12 | 3 |
| DEL PEAK 45(19Q11) WILD-TYPE | 16 | 22 | 28 | 22 | 5 |
Figure S315. Get High-res Image Gene #76: 'del_19q11' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0149 (Fisher's exact test), Q value = 0.055
Table S316. Gene #76: 'del_19q11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 45(19Q11) MUTATED | 21 | 1 | 15 | 10 |
| DEL PEAK 45(19Q11) WILD-TYPE | 41 | 25 | 47 | 23 |
Figure S316. Get High-res Image Gene #76: 'del_19q11' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00102 (Fisher's exact test), Q value = 0.0073
Table S317. Gene #76: 'del_19q11' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 45(19Q11) MUTATED | 17 | 23 | 1 | 4 |
| DEL PEAK 45(19Q11) WILD-TYPE | 49 | 43 | 34 | 7 |
Figure S317. Get High-res Image Gene #76: 'del_19q11' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0266 (Fisher's exact test), Q value = 0.08
Table S318. Gene #76: 'del_19q11' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 45(19Q11) MUTATED | 20 | 1 | 24 |
| DEL PEAK 45(19Q11) WILD-TYPE | 42 | 21 | 70 |
Figure S318. Get High-res Image Gene #76: 'del_19q11' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0342 (Fisher's exact test), Q value = 0.094
Table S319. Gene #77: 'del_20p12.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 46(20P12.1) MUTATED | 18 | 7 | 8 |
| DEL PEAK 46(20P12.1) WILD-TYPE | 47 | 37 | 67 |
Figure S319. Get High-res Image Gene #77: 'del_20p12.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00756 (Fisher's exact test), Q value = 0.034
Table S320. Gene #77: 'del_20p12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 46(20P12.1) MUTATED | 20 | 2 | 11 |
| DEL PEAK 46(20P12.1) WILD-TYPE | 47 | 18 | 85 |
Figure S320. Get High-res Image Gene #77: 'del_20p12.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0174 (Fisher's exact test), Q value = 0.061
Table S321. Gene #77: 'del_20p12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 46(20P12.1) MUTATED | 22 | 11 | 0 |
| DEL PEAK 46(20P12.1) WILD-TYPE | 62 | 76 | 12 |
Figure S321. Get High-res Image Gene #77: 'del_20p12.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0494 (Fisher's exact test), Q value = 0.12
Table S322. Gene #77: 'del_20p12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 46(20P12.1) MUTATED | 15 | 7 | 5 | 6 |
| DEL PEAK 46(20P12.1) WILD-TYPE | 47 | 19 | 57 | 27 |
Figure S322. Get High-res Image Gene #77: 'del_20p12.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0419 (Fisher's exact test), Q value = 0.11
Table S323. Gene #77: 'del_20p12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 46(20P12.1) MUTATED | 16 | 6 | 11 |
| DEL PEAK 46(20P12.1) WILD-TYPE | 46 | 16 | 83 |
Figure S323. Get High-res Image Gene #77: 'del_20p12.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0285 (Fisher's exact test), Q value = 0.084
Table S324. Gene #78: 'del_21q11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 47(21Q11.2) MUTATED | 53 | 16 | 38 |
| DEL PEAK 47(21Q11.2) WILD-TYPE | 23 | 16 | 38 |
Figure S324. Get High-res Image Gene #78: 'del_21q11.2' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0491 (Fisher's exact test), Q value = 0.12
Table S325. Gene #78: 'del_21q11.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 47(21Q11.2) MUTATED | 56 | 47 | 4 |
| DEL PEAK 47(21Q11.2) WILD-TYPE | 28 | 40 | 8 |
Figure S325. Get High-res Image Gene #78: 'del_21q11.2' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00901 (Fisher's exact test), Q value = 0.038
Table S326. Gene #79: 'del_21q21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 48(21Q21.1) MUTATED | 54 | 14 | 39 |
| DEL PEAK 48(21Q21.1) WILD-TYPE | 22 | 18 | 37 |
Figure S326. Get High-res Image Gene #79: 'del_21q21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.042
Table S327. Gene #80: 'del_21q22.12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 49(21Q22.12) MUTATED | 54 | 14 | 40 |
| DEL PEAK 49(21Q22.12) WILD-TYPE | 22 | 18 | 36 |
Figure S327. Get High-res Image Gene #80: 'del_21q22.12' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0473 (Fisher's exact test), Q value = 0.12
Table S328. Gene #80: 'del_21q22.12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 49(21Q22.12) MUTATED | 54 | 36 | 14 | 3 |
| DEL PEAK 49(21Q22.12) WILD-TYPE | 27 | 33 | 8 | 8 |
Figure S328. Get High-res Image Gene #80: 'del_21q22.12' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0325 (Fisher's exact test), Q value = 0.091
Table S329. Gene #80: 'del_21q22.12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 49(21Q22.12) MUTATED | 57 | 47 | 4 |
| DEL PEAK 49(21Q22.12) WILD-TYPE | 27 | 40 | 8 |
Figure S329. Get High-res Image Gene #80: 'del_21q22.12' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S330. Gene #81: 'del_22q11.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 50(22Q11.1) MUTATED | 46 | 13 | 20 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 19 | 31 | 55 |
Figure S330. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S331. Gene #81: 'del_22q11.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 50(22Q11.1) MUTATED | 51 | 10 | 18 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 25 | 22 | 58 |
Figure S331. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0034
Table S332. Gene #81: 'del_22q11.1' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| DEL PEAK 50(22Q11.1) MUTATED | 19 | 12 | 10 | 7 | 1 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 7 | 16 | 20 | 27 | 7 |
Figure S332. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00438 (Fisher's exact test), Q value = 0.022
Table S333. Gene #81: 'del_22q11.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 23 | 21 | 22 | 26 | 34 |
| DEL PEAK 50(22Q11.1) MUTATED | 14 | 12 | 9 | 8 | 6 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 9 | 9 | 13 | 18 | 28 |
Figure S333. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00048
Table S334. Gene #81: 'del_22q11.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 50(22Q11.1) MUTATED | 51 | 20 | 5 | 3 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 30 | 49 | 17 | 8 |
Figure S334. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S335. Gene #81: 'del_22q11.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 50(22Q11.1) MUTATED | 43 | 10 | 26 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 24 | 10 | 70 |
Figure S335. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S336. Gene #81: 'del_22q11.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 50(22Q11.1) MUTATED | 53 | 25 | 1 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 31 | 62 | 11 |
Figure S336. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S337. Gene #81: 'del_22q11.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 50(22Q11.1) MUTATED | 43 | 11 | 16 | 9 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 19 | 15 | 46 | 24 |
Figure S337. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S338. Gene #81: 'del_22q11.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 50(22Q11.1) MUTATED | 48 | 19 | 7 | 3 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 18 | 47 | 28 | 8 |
Figure S338. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00017
Table S339. Gene #81: 'del_22q11.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 50(22Q11.1) MUTATED | 44 | 9 | 24 |
| DEL PEAK 50(22Q11.1) WILD-TYPE | 18 | 13 | 70 |
Figure S339. Get High-res Image Gene #81: 'del_22q11.1' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00086 (Fisher's exact test), Q value = 0.0064
Table S340. Gene #82: 'del_xp21.1' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 51(XP21.1) MUTATED | 25 | 7 | 37 |
| DEL PEAK 51(XP21.1) WILD-TYPE | 40 | 37 | 38 |
Figure S340. Get High-res Image Gene #82: 'del_xp21.1' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0363 (Fisher's exact test), Q value = 0.098
Table S341. Gene #82: 'del_xp21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 76 | 32 | 76 |
| DEL PEAK 51(XP21.1) MUTATED | 26 | 7 | 36 |
| DEL PEAK 51(XP21.1) WILD-TYPE | 50 | 25 | 40 |
Figure S341. Get High-res Image Gene #82: 'del_xp21.1' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0371 (Fisher's exact test), Q value = 0.099
Table S342. Gene #82: 'del_xp21.1' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 26 | 28 | 30 | 34 | 8 |
| DEL PEAK 51(XP21.1) MUTATED | 11 | 9 | 10 | 21 | 1 |
| DEL PEAK 51(XP21.1) WILD-TYPE | 15 | 19 | 20 | 13 | 7 |
Figure S342. Get High-res Image Gene #82: 'del_xp21.1' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0125 (Fisher's exact test), Q value = 0.049
Table S343. Gene #82: 'del_xp21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 51(XP21.1) MUTATED | 27 | 34 | 3 | 5 |
| DEL PEAK 51(XP21.1) WILD-TYPE | 54 | 35 | 19 | 6 |
Figure S343. Get High-res Image Gene #82: 'del_xp21.1' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00088 (Fisher's exact test), Q value = 0.0064
Table S344. Gene #83: 'del_xp11.3' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 65 | 44 | 75 |
| DEL PEAK 52(XP11.3) MUTATED | 24 | 9 | 41 |
| DEL PEAK 52(XP11.3) WILD-TYPE | 41 | 35 | 34 |
Figure S344. Get High-res Image Gene #83: 'del_xp11.3' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.009 (Fisher's exact test), Q value = 0.038
Table S345. Gene #83: 'del_xp11.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 81 | 69 | 22 | 11 |
| DEL PEAK 52(XP11.3) MUTATED | 26 | 38 | 5 | 5 |
| DEL PEAK 52(XP11.3) WILD-TYPE | 55 | 31 | 17 | 6 |
Figure S345. Get High-res Image Gene #83: 'del_xp11.3' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0239 (Fisher's exact test), Q value = 0.075
Table S346. Gene #83: 'del_xp11.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 67 | 20 | 96 |
| DEL PEAK 52(XP11.3) MUTATED | 20 | 6 | 48 |
| DEL PEAK 52(XP11.3) WILD-TYPE | 47 | 14 | 48 |
Figure S346. Get High-res Image Gene #83: 'del_xp11.3' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00323 (Fisher's exact test), Q value = 0.017
Table S347. Gene #83: 'del_xp11.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 84 | 87 | 12 |
| DEL PEAK 52(XP11.3) MUTATED | 26 | 46 | 2 |
| DEL PEAK 52(XP11.3) WILD-TYPE | 58 | 41 | 10 |
Figure S347. Get High-res Image Gene #83: 'del_xp11.3' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0448 (Fisher's exact test), Q value = 0.11
Table S348. Gene #83: 'del_xp11.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 52(XP11.3) MUTATED | 21 | 6 | 29 | 18 |
| DEL PEAK 52(XP11.3) WILD-TYPE | 41 | 20 | 33 | 15 |
Figure S348. Get High-res Image Gene #83: 'del_xp11.3' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0328 (Fisher's exact test), Q value = 0.091
Table S349. Gene #83: 'del_xp11.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 66 | 66 | 35 | 11 |
| DEL PEAK 52(XP11.3) MUTATED | 21 | 36 | 11 | 4 |
| DEL PEAK 52(XP11.3) WILD-TYPE | 45 | 30 | 24 | 7 |
Figure S349. Get High-res Image Gene #83: 'del_xp11.3' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0179 (Fisher's exact test), Q value = 0.062
Table S350. Gene #83: 'del_xp11.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 62 | 22 | 94 |
| DEL PEAK 52(XP11.3) MUTATED | 20 | 5 | 47 |
| DEL PEAK 52(XP11.3) WILD-TYPE | 42 | 17 | 47 |
Figure S350. Get High-res Image Gene #83: 'del_xp11.3' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0284 (Fisher's exact test), Q value = 0.083
Table S351. Gene #85: 'del_xq21.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 62 | 26 | 62 | 33 |
| DEL PEAK 54(XQ21.33) MUTATED | 20 | 3 | 8 | 9 |
| DEL PEAK 54(XQ21.33) WILD-TYPE | 42 | 23 | 54 | 24 |
Figure S351. Get High-res Image Gene #85: 'del_xq21.33' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
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Copy number data file = all_lesions.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/ESCA-TP/19782630/transformed.cor.cli.txt
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Molecular subtype file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/ESCA-TP/20125286/ESCA-TP.transferedmergedcluster.txt
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Number of patients = 184
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Number of significantly focal cnvs = 85
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Number of molecular subtypes = 10
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Exclude genes that fewer than K tumors have alterations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.