This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 82 arm-level events and 14 molecular subtypes across 1090 patients, 549 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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2p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q gain cnv correlated to 'MIR_CNMF', 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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3q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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4p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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4q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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5p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p gain cnv correlated to 'MRNA_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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6q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'MIRSEQ_CNMF'.
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7p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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8q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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9q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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10p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q gain cnv correlated to 'METHLYATION_CNMF'.
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11p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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12q gain cnv correlated to 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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14q gain cnv correlated to 'MIR_CNMF' and 'CN_CNMF'.
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15q gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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16p gain cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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16q gain cnv correlated to 'MRNA_CNMF' and 'MRNA_CHIERARCHICAL'.
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17p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', and 'MRNASEQ_CNMF'.
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17q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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18p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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22q gain cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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xp gain cnv correlated to 'METHLYATION_CNMF'.
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xq gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q loss cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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2p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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2q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', and 'MIRSEQ_CNMF'.
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3p loss cnv correlated to 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q loss cnv correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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5q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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6p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7p loss cnv correlated to 'MRNA_CNMF'.
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7q loss cnv correlated to 'RPPA_CNMF'.
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8p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q loss cnv correlated to 'MIR_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p loss cnv correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9q loss cnv correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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12q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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13q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
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14q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', and 'METHLYATION_CNMF'.
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16p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'MRNA_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', and 'METHLYATION_CNMF'.
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18q loss cnv correlated to 'MRNA_CHIERARCHICAL' and 'METHLYATION_CNMF'.
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19p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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19q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', and 'MIR_CNMF'.
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20q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'CN_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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21q loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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22q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CNMF'.
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xq loss cnv correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 82 arm-level events and 14 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 549 significant findings detected.
|
Clinical Features |
MRNA CNMF |
MRNA CHIERARCHICAL |
MIR CNMF |
MIR CHIERARCHICAL |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 7p gain | 595 (55%) | 495 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00066 (0.00273) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
3e-05 (0.00019) |
9e-05 (0.000494) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00294 (0.0103) |
1e-05 (7.6e-05) |
0.00025 (0.00117) |
1e-05 (7.6e-05) |
| 7q gain | 631 (58%) | 459 |
2e-05 (0.000133) |
1e-05 (7.6e-05) |
0.00231 (0.00831) |
0.00012 (0.000626) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00371 (0.0124) |
0.0112 (0.0317) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00817 (0.0242) |
1e-05 (7.6e-05) |
0.00077 (0.00315) |
1e-05 (7.6e-05) |
| 20q gain | 263 (24%) | 827 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00276 (0.00969) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00032 (0.00145) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0254 (0.0622) |
1e-05 (7.6e-05) |
0.00019 (0.000916) |
1e-05 (7.6e-05) |
| 10p loss | 563 (52%) | 527 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0127 (0.0348) |
0.00012 (0.000626) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00018 (0.000872) |
0.0001 (0.000536) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
5e-05 (0.000302) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
| 10q loss | 591 (54%) | 499 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00307 (0.0106) |
0.00014 (0.000708) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
3e-05 (0.00019) |
7e-05 (0.000402) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
| 20p gain | 266 (24%) | 824 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00431 (0.014) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00155 (0.00572) |
2e-05 (0.000133) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.118 (0.207) |
1e-05 (7.6e-05) |
0.00247 (0.00881) |
1e-05 (7.6e-05) |
| 19p gain | 323 (30%) | 767 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0837 (0.157) |
0.00041 (0.00181) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0179 (0.0465) |
0.00117 (0.00446) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00147 (0.0055) |
0.0303 (0.0711) |
0.281 (0.399) |
0.0075 (0.0225) |
| 19q gain | 222 (20%) | 868 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.162 (0.262) |
0.00974 (0.0282) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0622 (0.122) |
0.00608 (0.0188) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00093 (0.00375) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
| 19q loss | 244 (22%) | 846 |
0.00699 (0.0212) |
0.0113 (0.0317) |
0.526 (0.63) |
0.182 (0.287) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00853 (0.0252) |
0.00016 (0.000788) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
| 4q loss | 151 (14%) | 939 |
0.00017 (0.00083) |
0.0002 (0.000961) |
0.0302 (0.0711) |
0.0999 (0.18) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.329 (0.449) |
1 (1.00) |
0.00942 (0.0274) |
0.00016 (0.000788) |
0.00013 (0.000672) |
0.00381 (0.0125) |
2e-05 (0.000133) |
5e-05 (0.000302) |
| 11p loss | 163 (15%) | 927 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.79 (0.844) |
0.0136 (0.037) |
0.00095 (0.00381) |
1e-05 (7.6e-05) |
0.0218 (0.0548) |
0.514 (0.62) |
0.00016 (0.000788) |
1e-05 (7.6e-05) |
2e-05 (0.000133) |
7e-05 (0.000402) |
0.35 (0.468) |
0.0177 (0.046) |
| 1p loss | 199 (18%) | 891 |
0.639 (0.728) |
0.829 (0.876) |
0.94 (0.962) |
0.196 (0.303) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0032 (0.011) |
3e-05 (0.00019) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
| 14q loss | 225 (21%) | 865 |
2e-05 (0.000133) |
0.0001 (0.000536) |
0.51 (0.619) |
0.539 (0.64) |
1e-05 (7.6e-05) |
0.00014 (0.000708) |
0.122 (0.211) |
0.283 (0.399) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00333 (0.0113) |
0.00219 (0.00791) |
0.00728 (0.0221) |
0.00058 (0.00246) |
| 1p gain | 95 (9%) | 995 |
0.605 (0.699) |
0.129 (0.22) |
0.486 (0.598) |
0.251 (0.366) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.105 (0.188) |
0.00584 (0.0182) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00592 (0.0184) |
1e-05 (7.6e-05) |
0.0125 (0.0345) |
0.00015 (0.000755) |
| 4p loss | 127 (12%) | 963 |
0.0469 (0.0994) |
0.00159 (0.00583) |
0.065 (0.126) |
0.173 (0.276) |
0.0153 (0.0411) |
1e-05 (7.6e-05) |
0.167 (0.269) |
0.909 (0.939) |
0.0721 (0.137) |
0.00156 (0.00574) |
6e-05 (0.000351) |
0.00033 (0.00149) |
2e-05 (0.000133) |
1e-05 (7.6e-05) |
| 6q loss | 189 (17%) | 901 |
0.936 (0.959) |
0.641 (0.728) |
0.565 (0.662) |
0.841 (0.883) |
2e-05 (0.000133) |
9e-05 (0.000494) |
0.0269 (0.0649) |
0.00162 (0.00592) |
9e-05 (0.000494) |
1e-05 (7.6e-05) |
0.00059 (0.00249) |
0.167 (0.269) |
0.0184 (0.0473) |
0.0001 (0.000536) |
| 11q loss | 113 (10%) | 977 |
3e-05 (0.00019) |
0.00032 (0.00145) |
0.915 (0.943) |
0.0764 (0.144) |
1e-05 (7.6e-05) |
6e-05 (0.000351) |
0.157 (0.256) |
0.627 (0.716) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0243 (0.0601) |
0.00017 (0.00083) |
0.332 (0.451) |
0.00107 (0.00415) |
| 17q loss | 51 (5%) | 1039 |
0.00527 (0.0169) |
0.0607 (0.12) |
0.251 (0.366) |
0.044 (0.0952) |
0.00024 (0.00112) |
0.00276 (0.00969) |
0.0175 (0.0457) |
0.0156 (0.0417) |
0.00149 (0.00555) |
0.00062 (0.00259) |
0.162 (0.262) |
0.265 (0.382) |
1 (1.00) |
0.0226 (0.0565) |
| 22q loss | 240 (22%) | 850 |
0.626 (0.716) |
0.583 (0.68) |
0.16 (0.259) |
0.829 (0.876) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00326 (0.0111) |
0.0312 (0.0722) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.453 (0.57) |
0.00026 (0.00121) |
0.0111 (0.0314) |
7e-05 (0.000402) |
| xp loss | 213 (20%) | 877 |
0.00582 (0.0182) |
0.008 (0.0239) |
0.0304 (0.0711) |
0.1 (0.181) |
0.216 (0.328) |
0.0729 (0.139) |
0.00097 (0.00387) |
0.0136 (0.037) |
0.01 (0.0288) |
0.0137 (0.0371) |
0.0379 (0.0843) |
0.244 (0.36) |
0.0394 (0.0871) |
0.112 (0.197) |
| 5p gain | 60 (6%) | 1030 |
0.113 (0.199) |
0.155 (0.254) |
0.175 (0.279) |
0.345 (0.463) |
2e-05 (0.000133) |
0.0058 (0.0182) |
0.283 (0.399) |
0.00813 (0.0242) |
2e-05 (0.000133) |
2e-05 (0.000133) |
0.0241 (0.0597) |
0.0278 (0.0664) |
0.144 (0.239) |
0.0159 (0.0421) |
| 5q gain | 50 (5%) | 1040 |
0.141 (0.236) |
0.232 (0.345) |
0.118 (0.207) |
0.0534 (0.11) |
1e-05 (7.6e-05) |
0.0006 (0.00252) |
0.745 (0.811) |
0.0136 (0.037) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0741 (0.14) |
0.00623 (0.0192) |
0.0458 (0.0981) |
0.00478 (0.0154) |
| 8q gain | 118 (11%) | 972 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0403 (0.0882) |
0.455 (0.571) |
0.0182 (0.047) |
1e-05 (7.6e-05) |
0.467 (0.58) |
0.248 (0.364) |
0.12 (0.209) |
0.00098 (0.00389) |
0.156 (0.254) |
0.098 (0.178) |
0.0353 (0.0794) |
0.0105 (0.03) |
| 12q gain | 66 (6%) | 1024 |
0.52 (0.626) |
0.955 (0.975) |
0.535 (0.636) |
0.0103 (0.0296) |
0.00014 (0.000708) |
0.0403 (0.0882) |
0.00031 (0.00142) |
0.365 (0.481) |
0.00117 (0.00446) |
0.00139 (0.00521) |
0.019 (0.0489) |
0.00364 (0.0123) |
0.0543 (0.111) |
0.0749 (0.142) |
| 17q gain | 86 (8%) | 1004 |
0.00103 (0.00402) |
0.0467 (0.099) |
0.127 (0.218) |
0.0311 (0.0721) |
0.00011 (0.000582) |
0.291 (0.406) |
0.0394 (0.0871) |
0.519 (0.626) |
0.0015 (0.00555) |
0.0274 (0.0658) |
0.0255 (0.0623) |
0.472 (0.586) |
0.13 (0.221) |
0.193 (0.3) |
| 18q gain | 75 (7%) | 1015 |
1e-05 (7.6e-05) |
0.00035 (0.00156) |
0.124 (0.213) |
0.394 (0.512) |
0.0001 (0.000536) |
0.00085 (0.00346) |
0.171 (0.273) |
0.135 (0.227) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.354 (0.474) |
0.00977 (0.0282) |
0.283 (0.399) |
0.00086 (0.00349) |
| 21q gain | 88 (8%) | 1002 |
0.00117 (0.00446) |
0.00755 (0.0226) |
0.0114 (0.0319) |
0.00375 (0.0125) |
5e-05 (0.000302) |
0.0203 (0.0514) |
0.258 (0.375) |
0.122 (0.211) |
0.00023 (0.00109) |
1e-05 (7.6e-05) |
0.62 (0.713) |
0.0999 (0.18) |
0.727 (0.796) |
0.082 (0.154) |
| 5q loss | 78 (7%) | 1012 |
1e-05 (7.6e-05) |
3e-05 (0.00019) |
0.00054 (0.0023) |
0.146 (0.243) |
0.0007 (0.00288) |
0.00021 (0.001) |
0.0369 (0.0825) |
0.0552 (0.112) |
0.0652 (0.126) |
0.00541 (0.0171) |
0.00041 (0.00181) |
0.3 (0.416) |
0.81 (0.86) |
0.879 (0.915) |
| 9p loss | 319 (29%) | 771 |
0.00346 (0.0118) |
0.112 (0.197) |
0.525 (0.63) |
0.396 (0.513) |
6e-05 (0.000351) |
2e-05 (0.000133) |
0.00205 (0.00742) |
0.00542 (0.0171) |
0.00659 (0.0201) |
0.0106 (0.0301) |
0.896 (0.929) |
0.219 (0.331) |
0.28 (0.399) |
0.0334 (0.0763) |
| 16q loss | 105 (10%) | 985 |
0.0593 (0.118) |
0.425 (0.545) |
0.466 (0.58) |
0.897 (0.93) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00822 (0.0243) |
5e-05 (0.000302) |
1e-05 (7.6e-05) |
2e-05 (0.000133) |
0.667 (0.75) |
0.00353 (0.0119) |
0.293 (0.408) |
0.00906 (0.0265) |
| 17p loss | 77 (7%) | 1013 |
0.0229 (0.0569) |
0.0278 (0.0664) |
0.669 (0.751) |
0.487 (0.598) |
2e-05 (0.000133) |
0.00064 (0.00265) |
0.137 (0.231) |
0.194 (0.301) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.159 (0.259) |
0.00639 (0.0196) |
0.713 (0.784) |
0.0119 (0.033) |
| 3p gain | 67 (6%) | 1023 |
0.00012 (0.000626) |
0.0117 (0.0326) |
0.666 (0.75) |
0.0306 (0.0715) |
2e-05 (0.000133) |
0.0275 (0.0659) |
0.127 (0.218) |
0.438 (0.555) |
0.00028 (0.0013) |
0.00031 (0.00142) |
0.0706 (0.135) |
0.45 (0.567) |
0.787 (0.843) |
0.384 (0.501) |
| 3q gain | 71 (7%) | 1019 |
0.00021 (0.001) |
0.0351 (0.0793) |
0.922 (0.947) |
0.0637 (0.124) |
2e-05 (0.000133) |
0.0005 (0.00218) |
0.0462 (0.0987) |
0.361 (0.479) |
1e-05 (7.6e-05) |
2e-05 (0.000133) |
0.344 (0.463) |
0.135 (0.228) |
0.329 (0.449) |
0.151 (0.249) |
| 9p gain | 64 (6%) | 1026 |
0.00372 (0.0124) |
0.0307 (0.0717) |
0.704 (0.777) |
0.431 (0.548) |
2e-05 (0.000133) |
0.0174 (0.0457) |
0.145 (0.242) |
0.278 (0.397) |
0.00042 (0.00185) |
0.00054 (0.0023) |
0.682 (0.759) |
0.0257 (0.0625) |
1 (1.00) |
0.235 (0.348) |
| 10p gain | 70 (6%) | 1020 |
0.001 (0.00393) |
8e-05 (0.000452) |
0.118 (0.207) |
0.059 (0.118) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.289 (0.405) |
0.138 (0.232) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.0542 (0.111) |
0.294 (0.408) |
0.474 (0.587) |
0.00475 (0.0153) |
| 11q gain | 74 (7%) | 1016 |
0.126 (0.216) |
0.0643 (0.125) |
0.456 (0.572) |
0.242 (0.357) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.169 (0.271) |
0.0481 (0.101) |
4e-05 (0.000247) |
1e-05 (7.6e-05) |
0.623 (0.715) |
0.0376 (0.084) |
0.754 (0.819) |
0.0319 (0.0734) |
| 18p gain | 78 (7%) | 1012 |
1e-05 (7.6e-05) |
0.00053 (0.00228) |
0.157 (0.256) |
0.364 (0.481) |
0.00238 (0.00854) |
0.0157 (0.0417) |
0.589 (0.685) |
0.107 (0.191) |
9e-05 (0.000494) |
0.00031 (0.00142) |
0.756 (0.819) |
0.0781 (0.147) |
0.747 (0.812) |
0.0349 (0.0788) |
| 3p loss | 71 (7%) | 1019 |
0.839 (0.882) |
0.918 (0.944) |
0.795 (0.847) |
0.172 (0.275) |
0.818 (0.868) |
0.249 (0.365) |
0.0391 (0.0868) |
0.0333 (0.0763) |
0.0258 (0.0625) |
0.0425 (0.0923) |
0.00088 (0.00356) |
0.00052 (0.00224) |
0.196 (0.304) |
0.00274 (0.00968) |
| 6p loss | 116 (11%) | 974 |
0.571 (0.667) |
0.425 (0.545) |
0.777 (0.835) |
0.65 (0.736) |
1e-05 (7.6e-05) |
0.00014 (0.000708) |
0.147 (0.243) |
0.0152 (0.0407) |
2e-05 (0.000133) |
1e-05 (7.6e-05) |
0.543 (0.642) |
0.232 (0.345) |
0.00397 (0.0129) |
0.00137 (0.00517) |
| 8p loss | 74 (7%) | 1016 |
0.546 (0.646) |
0.442 (0.559) |
0.18 (0.285) |
0.775 (0.833) |
6e-05 (0.000351) |
1e-05 (7.6e-05) |
0.357 (0.476) |
0.378 (0.494) |
1e-05 (7.6e-05) |
3e-05 (0.00019) |
0.0338 (0.0769) |
0.00104 (0.00405) |
0.762 (0.823) |
0.00035 (0.00156) |
| 8q loss | 52 (5%) | 1038 |
0.736 (0.803) |
0.208 (0.318) |
0.0382 (0.0849) |
0.746 (0.812) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.336 (0.455) |
0.611 (0.704) |
3e-05 (0.00019) |
1e-05 (7.6e-05) |
0.0525 (0.109) |
0.00058 (0.00246) |
0.371 (0.486) |
7e-05 (0.000402) |
| 13q loss | 298 (27%) | 792 |
4e-05 (0.000247) |
0.0015 (0.00555) |
0.749 (0.813) |
0.588 (0.685) |
9e-05 (0.000494) |
0.0169 (0.0447) |
0.105 (0.188) |
0.824 (0.873) |
0.00052 (0.00224) |
0.00036 (0.0016) |
0.0615 (0.121) |
0.00921 (0.0269) |
0.226 (0.338) |
0.262 (0.379) |
| xq loss | 174 (16%) | 916 |
0.0175 (0.0457) |
0.0254 (0.0622) |
0.12 (0.209) |
0.12 (0.209) |
0.626 (0.716) |
0.00269 (0.00953) |
8e-05 (0.000452) |
0.0694 (0.133) |
0.00111 (0.00429) |
0.142 (0.237) |
0.00011 (0.000582) |
0.355 (0.474) |
0.108 (0.192) |
0.03 (0.0709) |
| 1q gain | 112 (10%) | 978 |
0.077 (0.145) |
0.0895 (0.167) |
0.131 (0.221) |
0.623 (0.715) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.138 (0.232) |
0.102 (0.184) |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.121 (0.21) |
0.0309 (0.0719) |
0.0309 (0.0719) |
0.0581 (0.116) |
| 2q gain | 48 (4%) | 1042 |
0.666 (0.75) |
0.911 (0.939) |
0.0497 (0.104) |
0.205 (0.315) |
0.00379 (0.0125) |
0.0564 (0.114) |
0.15 (0.248) |
0.343 (0.462) |
0.0039 (0.0128) |
0.00064 (0.00265) |
0.509 (0.619) |
0.0174 (0.0457) |
0.685 (0.761) |
0.0465 (0.0988) |
| 12p gain | 94 (9%) | 996 |
0.67 (0.751) |
0.794 (0.847) |
0.647 (0.733) |
0.166 (0.268) |
0.0888 (0.165) |
0.00259 (0.00921) |
0.00655 (0.02) |
0.359 (0.476) |
0.00473 (0.0153) |
0.0196 (0.0499) |
0.0318 (0.0734) |
0.00778 (0.0233) |
0.0912 (0.169) |
0.507 (0.617) |
| 17p gain | 72 (7%) | 1018 |
0.00016 (0.000788) |
0.0107 (0.0304) |
0.0601 (0.119) |
0.0193 (0.0496) |
0.00168 (0.0061) |
0.465 (0.579) |
0.017 (0.0448) |
0.275 (0.393) |
0.0413 (0.09) |
0.293 (0.408) |
0.0932 (0.172) |
0.722 (0.792) |
0.426 (0.545) |
0.453 (0.57) |
| 5p loss | 79 (7%) | 1011 |
1e-05 (7.6e-05) |
1e-05 (7.6e-05) |
0.00096 (0.00384) |
0.0732 (0.139) |
0.00051 (0.00222) |
9e-05 (0.000494) |
0.348 (0.466) |
0.448 (0.565) |
0.152 (0.249) |
0.0448 (0.0963) |
0.188 (0.294) |
0.458 (0.573) |
0.74 (0.806) |
0.5 (0.61) |
| 9q loss | 143 (13%) | 947 |
0.169 (0.271) |
0.0329 (0.0756) |
0.131 (0.222) |
0.186 (0.292) |
0.0252 (0.0618) |
0.188 (0.294) |
0.21 (0.321) |
0.048 (0.101) |
0.00578 (0.0182) |
0.0245 (0.0602) |
0.421 (0.541) |
0.678 (0.756) |
0.513 (0.62) |
0.0204 (0.0515) |
| 15q loss | 156 (14%) | 934 |
4e-05 (0.000247) |
1e-05 (7.6e-05) |
0.0038 (0.0125) |
0.00366 (0.0123) |
0.0443 (0.0953) |
0.00121 (0.0046) |
0.107 (0.19) |
0.287 (0.403) |
0.0515 (0.107) |
0.513 (0.62) |
0.168 (0.27) |
0.487 (0.598) |
0.0521 (0.108) |
0.0649 (0.126) |
| 2p gain | 51 (5%) | 1039 |
0.469 (0.582) |
0.732 (0.801) |
0.25 (0.365) |
0.226 (0.338) |
0.001 (0.00393) |
0.248 (0.364) |
0.188 (0.294) |
0.489 (0.599) |
0.003 (0.0104) |
0.00247 (0.00881) |
0.601 (0.697) |
0.0222 (0.0555) |
0.89 (0.925) |
0.0396 (0.0874) |
| 4p gain | 47 (4%) | 1043 |
0.364 (0.481) |
0.755 (0.819) |
0.594 (0.689) |
0.486 (0.598) |
0.0581 (0.116) |
0.0428 (0.0927) |
0.385 (0.501) |
0.0404 (0.0883) |
0.00308 (0.0106) |
0.00034 (0.00153) |
0.254 (0.37) |
0.0442 (0.0953) |
0.306 (0.422) |
0.284 (0.399) |
| 6p gain | 35 (3%) | 1055 |
0.0161 (0.0427) |
0.0989 (0.18) |
0.895 (0.929) |
0.282 (0.399) |
0.0699 (0.134) |
0.0229 (0.0569) |
0.00966 (0.028) |
0.559 (0.659) |
0.141 (0.236) |
0.281 (0.399) |
0.0111 (0.0314) |
0.0232 (0.0575) |
0.342 (0.462) |
0.287 (0.403) |
| 9q gain | 96 (9%) | 994 |
0.0509 (0.106) |
0.05 (0.104) |
0.528 (0.63) |
0.128 (0.218) |
3e-05 (0.00019) |
0.0142 (0.0383) |
0.129 (0.219) |
0.227 (0.339) |
0.00014 (0.000708) |
0.00282 (0.00987) |
0.296 (0.411) |
0.0106 (0.0301) |
0.606 (0.699) |
0.121 (0.21) |
| 11p gain | 50 (5%) | 1040 |
0.903 (0.934) |
0.88 (0.915) |
0.645 (0.732) |
0.945 (0.966) |
0.0139 (0.0376) |
0.00016 (0.000788) |
0.347 (0.466) |
0.396 (0.513) |
0.0975 (0.178) |
0.0118 (0.0327) |
0.0905 (0.168) |
0.0115 (0.0321) |
0.247 (0.364) |
0.00382 (0.0125) |
| 15q gain | 36 (3%) | 1054 |
0.0612 (0.12) |
0.108 (0.192) |
0.567 (0.663) |
0.131 (0.222) |
0.0618 (0.121) |
0.0261 (0.063) |
0.0461 (0.0986) |
0.00304 (0.0105) |
0.0158 (0.042) |
0.00376 (0.0125) |
0.225 (0.338) |
0.439 (0.556) |
0.712 (0.784) |
0.282 (0.399) |
| 16p gain | 54 (5%) | 1036 |
0.0074 (0.0223) |
0.0654 (0.126) |
0.416 (0.535) |
0.272 (0.389) |
0.0221 (0.0555) |
0.879 (0.915) |
0.561 (0.66) |
0.0455 (0.0976) |
0.0476 (0.101) |
0.863 (0.902) |
0.18 (0.285) |
0.0194 (0.0496) |
0.109 (0.192) |
0.411 (0.53) |
| 22q gain | 55 (5%) | 1035 |
1e-05 (7.6e-05) |
0.00649 (0.0199) |
0.31 (0.426) |
0.316 (0.434) |
0.686 (0.762) |
2e-05 (0.000133) |
0.441 (0.558) |
0.228 (0.34) |
0.397 (0.514) |
0.0136 (0.037) |
0.119 (0.208) |
0.528 (0.63) |
0.0406 (0.0887) |
0.224 (0.337) |
| xq gain | 59 (5%) | 1031 |
0.431 (0.548) |
0.968 (0.987) |
0.92 (0.946) |
0.519 (0.625) |
0.00351 (0.0119) |
1e-05 (7.6e-05) |
0.334 (0.453) |
0.282 (0.399) |
0.0424 (0.0923) |
0.00071 (0.00291) |
0.0582 (0.116) |
0.46 (0.574) |
0.839 (0.882) |
0.0226 (0.0565) |
| 16p loss | 78 (7%) | 1012 |
0.289 (0.405) |
0.851 (0.891) |
0.662 (0.748) |
0.734 (0.801) |
2e-05 (0.000133) |
0.00406 (0.0132) |
0.0613 (0.121) |
0.0073 (0.0221) |
0.00018 (0.000872) |
0.00045 (0.00197) |
0.934 (0.958) |
0.46 (0.574) |
0.512 (0.62) |
0.0967 (0.177) |
| 4q gain | 40 (4%) | 1050 |
0.584 (0.68) |
0.319 (0.436) |
0.527 (0.63) |
0.541 (0.642) |
0.0284 (0.0677) |
0.00606 (0.0188) |
0.376 (0.492) |
0.192 (0.299) |
2e-05 (0.000133) |
6e-05 (0.000351) |
0.221 (0.333) |
0.0543 (0.111) |
0.233 (0.347) |
0.0673 (0.13) |
| 6q gain | 28 (3%) | 1062 |
0.00166 (0.00605) |
0.0358 (0.0804) |
0.785 (0.841) |
0.103 (0.185) |
0.0296 (0.0701) |
0.125 (0.216) |
0.0954 (0.175) |
0.863 (0.902) |
0.366 (0.482) |
0.301 (0.416) |
0.00595 (0.0185) |
0.151 (0.248) |
1 (1.00) |
0.872 (0.909) |
| 8p gain | 101 (9%) | 989 |
4e-05 (0.000247) |
0.00062 (0.00259) |
0.0628 (0.123) |
0.559 (0.659) |
0.195 (0.302) |
0.00022 (0.00104) |
0.429 (0.548) |
0.177 (0.282) |
0.371 (0.486) |
0.0139 (0.0376) |
0.482 (0.595) |
0.326 (0.445) |
0.122 (0.211) |
0.0568 (0.114) |
| 2p loss | 54 (5%) | 1036 |
0.0299 (0.0708) |
0.0287 (0.0682) |
0.262 (0.379) |
0.772 (0.83) |
0.0593 (0.118) |
0.0245 (0.0602) |
0.127 (0.218) |
0.524 (0.63) |
0.2 (0.308) |
0.0464 (0.0988) |
0.0712 (0.136) |
0.396 (0.513) |
0.492 (0.602) |
0.202 (0.311) |
| 2q loss | 52 (5%) | 1038 |
0.034 (0.0772) |
0.0132 (0.0362) |
0.203 (0.313) |
0.664 (0.749) |
0.225 (0.337) |
0.0199 (0.0505) |
0.0541 (0.111) |
0.267 (0.384) |
0.584 (0.68) |
0.056 (0.113) |
0.0332 (0.0761) |
0.674 (0.753) |
0.678 (0.756) |
0.64 (0.728) |
| 3q loss | 64 (6%) | 1026 |
0.223 (0.336) |
0.204 (0.314) |
0.599 (0.694) |
0.84 (0.882) |
0.533 (0.634) |
0.155 (0.254) |
0.0959 (0.176) |
0.0901 (0.167) |
0.0992 (0.18) |
0.0341 (0.0772) |
0.048 (0.101) |
0.0124 (0.0342) |
0.306 (0.422) |
0.0319 (0.0734) |
| 12q loss | 109 (10%) | 981 |
0.245 (0.361) |
0.239 (0.354) |
0.405 (0.523) |
0.698 (0.772) |
0.00542 (0.0171) |
1e-05 (7.6e-05) |
0.256 (0.372) |
0.834 (0.879) |
0.661 (0.748) |
6e-05 (0.000351) |
0.00947 (0.0275) |
0.426 (0.545) |
0.603 (0.698) |
0.966 (0.986) |
| 19p loss | 57 (5%) | 1033 |
0.00099 (0.00392) |
0.00301 (0.0104) |
0.0961 (0.176) |
0.316 (0.433) |
0.00903 (0.0265) |
0.671 (0.752) |
0.0965 (0.176) |
0.973 (0.991) |
0.179 (0.284) |
0.665 (0.749) |
0.182 (0.287) |
0.152 (0.25) |
0.00549 (0.0173) |
0.0535 (0.11) |
| 20q loss | 21 (2%) | 1069 |
0.00134 (0.00508) |
0.0001 (0.000536) |
0.365 (0.481) |
0.269 (0.386) |
0.00502 (0.0161) |
0.309 (0.426) |
0.264 (0.381) |
0.673 (0.752) |
0.717 (0.788) |
0.0125 (0.0344) |
0.762 (0.823) |
0.543 (0.642) |
0.835 (0.88) |
1 (1.00) |
| 21q loss | 79 (7%) | 1011 |
0.0215 (0.0543) |
0.00112 (0.00431) |
0.0524 (0.108) |
0.264 (0.381) |
0.0676 (0.13) |
4e-05 (0.000247) |
0.382 (0.499) |
0.632 (0.722) |
0.178 (0.284) |
2e-05 (0.000133) |
0.331 (0.451) |
0.0543 (0.111) |
0.713 (0.784) |
0.415 (0.535) |
| 12p loss | 86 (8%) | 1004 |
0.213 (0.324) |
0.248 (0.364) |
0.562 (0.66) |
0.788 (0.843) |
0.0273 (0.0656) |
0.0489 (0.102) |
0.77 (0.83) |
0.697 (0.771) |
0.249 (0.364) |
0.0182 (0.047) |
0.0602 (0.119) |
0.28 (0.399) |
0.316 (0.433) |
0.772 (0.83) |
| 18p loss | 137 (13%) | 953 |
0.0477 (0.101) |
0.0336 (0.0765) |
0.358 (0.476) |
0.219 (0.331) |
0.563 (0.66) |
0.0259 (0.0628) |
0.35 (0.468) |
0.213 (0.324) |
0.904 (0.935) |
0.62 (0.713) |
0.457 (0.573) |
0.87 (0.908) |
0.404 (0.522) |
0.503 (0.613) |
| 20p loss | 26 (2%) | 1064 |
0.00013 (0.000672) |
8e-05 (0.000452) |
0.0363 (0.0813) |
0.0935 (0.172) |
0.0566 (0.114) |
0.191 (0.298) |
0.316 (0.433) |
0.093 (0.172) |
0.642 (0.73) |
0.182 (0.287) |
0.444 (0.561) |
0.484 (0.596) |
0.713 (0.784) |
0.481 (0.595) |
| 14q gain | 26 (2%) | 1064 |
0.431 (0.548) |
0.778 (0.835) |
0.0104 (0.0297) |
0.807 (0.858) |
0.00024 (0.00112) |
0.482 (0.595) |
1 (1.00) |
0.672 (0.752) |
0.106 (0.188) |
0.0772 (0.145) |
0.367 (0.482) |
0.68 (0.758) |
0.269 (0.386) |
0.76 (0.822) |
| 16q gain | 56 (5%) | 1034 |
0.018 (0.0466) |
0.00537 (0.0171) |
0.356 (0.474) |
0.0661 (0.128) |
0.0562 (0.114) |
0.342 (0.462) |
0.792 (0.846) |
0.129 (0.219) |
0.364 (0.481) |
0.466 (0.58) |
0.0544 (0.111) |
0.0997 (0.18) |
0.14 (0.234) |
0.532 (0.633) |
| 1q loss | 44 (4%) | 1046 |
0.832 (0.878) |
0.977 (0.994) |
0.856 (0.896) |
0.361 (0.479) |
0.209 (0.319) |
0.0196 (0.0499) |
0.524 (0.63) |
0.101 (0.182) |
0.207 (0.318) |
0.0402 (0.0882) |
0.214 (0.324) |
0.369 (0.484) |
0.241 (0.356) |
0.161 (0.262) |
| 18q loss | 123 (11%) | 967 |
0.181 (0.285) |
0.00866 (0.0255) |
0.64 (0.728) |
0.329 (0.449) |
0.511 (0.619) |
0.00101 (0.00396) |
0.29 (0.405) |
0.481 (0.595) |
1 (1.00) |
0.288 (0.404) |
0.0572 (0.115) |
0.712 (0.784) |
0.417 (0.536) |
0.531 (0.633) |
| 10q gain | 12 (1%) | 1078 |
0.555 (0.655) |
1 (1.00) |
0.0528 (0.109) |
0.796 (0.847) |
0.0738 (0.14) |
0.00139 (0.00521) |
0.343 (0.462) |
0.103 (0.185) |
0.725 (0.795) |
0.122 (0.211) |
0.147 (0.243) |
0.16 (0.259) |
0.767 (0.828) |
0.562 (0.66) |
| xp gain | 35 (3%) | 1055 |
0.283 (0.399) |
1 (1.00) |
0.796 (0.847) |
0.184 (0.289) |
0.691 (0.766) |
0.00011 (0.000582) |
0.223 (0.336) |
0.672 (0.752) |
0.459 (0.574) |
0.733 (0.801) |
0.621 (0.713) |
0.91 (0.939) |
0.917 (0.944) |
0.492 (0.602) |
| 7p loss | 10 (1%) | 1080 |
0.0302 (0.0711) |
0.0872 (0.163) |
0.215 (0.327) |
0.06 (0.119) |
0.427 (0.545) |
0.131 (0.222) |
1 (1.00) |
1 (1.00) |
1 (1.00) |
1 (1.00) |
||||
| 7q loss | 9 (1%) | 1081 |
0.0939 (0.173) |
0.614 (0.708) |
0.59 (0.685) |
0.213 (0.324) |
0.563 (0.661) |
0.0873 (0.163) |
0.0378 (0.0843) |
0.372 (0.487) |
0.687 (0.762) |
1 (1.00) |
1 (1.00) |
0.832 (0.878) |
0.208 (0.318) |
1 (1.00) |
| 13q gain | 17 (2%) | 1073 |
0.0529 (0.109) |
0.496 (0.606) |
0.18 (0.285) |
0.824 (0.873) |
0.849 (0.89) |
0.338 (0.457) |
0.931 (0.955) |
0.636 (0.726) |
0.256 (0.372) |
0.53 (0.632) |
0.291 (0.406) |
0.43 (0.548) |
0.272 (0.389) |
0.498 (0.607) |
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S1. Gene #1: '1p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 1P GAIN MUTATED | 79 | 10 | 6 |
| 1P GAIN WILD-TYPE | 454 | 532 | 9 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S2. Gene #1: '1p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 1P GAIN MUTATED | 20 | 5 | 0 | 0 |
| 1P GAIN WILD-TYPE | 164 | 232 | 64 | 165 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00584 (Fisher's exact test), Q value = 0.018
Table S3. Gene #1: '1p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 1P GAIN MUTATED | 18 | 19 | 2 |
| 1P GAIN WILD-TYPE | 216 | 235 | 156 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S4. Gene #1: '1p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 1P GAIN MUTATED | 36 | 3 | 0 |
| 1P GAIN WILD-TYPE | 197 | 232 | 192 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S5. Gene #1: '1p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 1P GAIN MUTATED | 33 | 6 | 0 |
| 1P GAIN WILD-TYPE | 170 | 184 | 267 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00592 (Fisher's exact test), Q value = 0.018
Table S6. Gene #1: '1p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 1P GAIN MUTATED | 8 | 4 | 1 | 0 |
| 1P GAIN WILD-TYPE | 129 | 103 | 182 | 82 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S7. Gene #1: '1p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 1P GAIN MUTATED | 3 | 0 | 10 |
| 1P GAIN WILD-TYPE | 219 | 184 | 93 |
Figure S7. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0125 (Fisher's exact test), Q value = 0.035
Table S8. Gene #1: '1p gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 1P GAIN MUTATED | 10 | 1 | 2 |
| 1P GAIN WILD-TYPE | 175 | 160 | 157 |
Figure S8. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.00076
Table S9. Gene #1: '1p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 1P GAIN MUTATED | 1 | 2 | 1 | 9 |
| 1P GAIN WILD-TYPE | 90 | 135 | 187 | 80 |
Figure S9. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S10. Gene #2: '1q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 1Q GAIN MUTATED | 83 | 23 | 6 |
| 1Q GAIN WILD-TYPE | 450 | 519 | 9 |
Figure S10. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S11. Gene #2: '1q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 1Q GAIN MUTATED | 26 | 9 | 1 | 2 |
| 1Q GAIN WILD-TYPE | 158 | 228 | 63 | 163 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S12. Gene #2: '1q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 1Q GAIN MUTATED | 39 | 5 | 6 |
| 1Q GAIN WILD-TYPE | 194 | 230 | 186 |
Figure S12. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S13. Gene #2: '1q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 1Q GAIN MUTATED | 35 | 9 | 6 |
| 1Q GAIN WILD-TYPE | 168 | 181 | 261 |
Figure S13. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0309 (Fisher's exact test), Q value = 0.072
Table S14. Gene #2: '1q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 1Q GAIN MUTATED | 7 | 6 | 10 |
| 1Q GAIN WILD-TYPE | 215 | 178 | 93 |
Figure S14. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0309 (Fisher's exact test), Q value = 0.072
Table S15. Gene #2: '1q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 1Q GAIN MUTATED | 12 | 2 | 9 |
| 1Q GAIN WILD-TYPE | 173 | 159 | 150 |
Figure S15. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.001 (Fisher's exact test), Q value = 0.0039
Table S16. Gene #3: '2p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 2P GAIN MUTATED | 37 | 13 | 1 |
| 2P GAIN WILD-TYPE | 496 | 529 | 14 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.003 (Fisher's exact test), Q value = 0.01
Table S17. Gene #3: '2p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 2P GAIN MUTATED | 17 | 5 | 3 |
| 2P GAIN WILD-TYPE | 216 | 230 | 189 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00247 (Fisher's exact test), Q value = 0.0088
Table S18. Gene #3: '2p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 2P GAIN MUTATED | 16 | 4 | 5 |
| 2P GAIN WILD-TYPE | 187 | 186 | 262 |
Figure S18. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0222 (Fisher's exact test), Q value = 0.056
Table S19. Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 2P GAIN MUTATED | 5 | 2 | 7 |
| 2P GAIN WILD-TYPE | 217 | 182 | 96 |
Figure S19. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0396 (Fisher's exact test), Q value = 0.087
Table S20. Gene #3: '2p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 2P GAIN MUTATED | 1 | 5 | 2 | 6 |
| 2P GAIN WILD-TYPE | 90 | 132 | 186 | 83 |
Figure S20. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0497 (Fisher's exact test), Q value = 0.1
Table S21. Gene #4: '2q gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 2Q GAIN MUTATED | 8 | 11 | 2 | 14 |
| 2Q GAIN WILD-TYPE | 148 | 172 | 85 | 106 |
Figure S21. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00379 (Fisher's exact test), Q value = 0.013
Table S22. Gene #4: '2q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 2Q GAIN MUTATED | 34 | 13 | 1 |
| 2Q GAIN WILD-TYPE | 499 | 529 | 14 |
Figure S22. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0039 (Fisher's exact test), Q value = 0.013
Table S23. Gene #4: '2q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 2Q GAIN MUTATED | 16 | 4 | 3 |
| 2Q GAIN WILD-TYPE | 217 | 231 | 189 |
Figure S23. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00064 (Fisher's exact test), Q value = 0.0027
Table S24. Gene #4: '2q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 2Q GAIN MUTATED | 16 | 3 | 4 |
| 2Q GAIN WILD-TYPE | 187 | 187 | 263 |
Figure S24. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0174 (Fisher's exact test), Q value = 0.046
Table S25. Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 2Q GAIN MUTATED | 4 | 2 | 7 |
| 2Q GAIN WILD-TYPE | 218 | 182 | 96 |
Figure S25. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0465 (Fisher's exact test), Q value = 0.099
Table S26. Gene #4: '2q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 2Q GAIN MUTATED | 1 | 4 | 2 | 6 |
| 2Q GAIN WILD-TYPE | 90 | 133 | 186 | 83 |
Figure S26. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00063
Table S27. Gene #5: '3p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 3P GAIN MUTATED | 16 | 18 | 4 | 15 |
| 3P GAIN WILD-TYPE | 131 | 78 | 148 | 98 |
Figure S27. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0117 (Fisher's exact test), Q value = 0.033
Table S28. Gene #5: '3p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 3P GAIN MUTATED | 13 | 18 | 4 | 18 |
| 3P GAIN WILD-TYPE | 135 | 84 | 96 | 140 |
Figure S28. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0306 (Fisher's exact test), Q value = 0.072
Table S29. Gene #5: '3p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 3P GAIN MUTATED | 35 | 5 | 14 |
| 3P GAIN WILD-TYPE | 258 | 119 | 115 |
Figure S29. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S30. Gene #5: '3p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 3P GAIN MUTATED | 51 | 14 | 2 |
| 3P GAIN WILD-TYPE | 482 | 528 | 13 |
Figure S30. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0275 (Fisher's exact test), Q value = 0.066
Table S31. Gene #5: '3p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 3P GAIN MUTATED | 13 | 5 | 1 | 3 |
| 3P GAIN WILD-TYPE | 171 | 232 | 63 | 162 |
Figure S31. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00028 (Fisher's exact test), Q value = 0.0013
Table S32. Gene #5: '3p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 3P GAIN MUTATED | 21 | 5 | 3 |
| 3P GAIN WILD-TYPE | 212 | 230 | 189 |
Figure S32. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0014
Table S33. Gene #5: '3p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 3P GAIN MUTATED | 19 | 6 | 4 |
| 3P GAIN WILD-TYPE | 184 | 184 | 263 |
Figure S33. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00021 (Fisher's exact test), Q value = 0.001
Table S34. Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 3Q GAIN MUTATED | 17 | 21 | 6 | 15 |
| 3Q GAIN WILD-TYPE | 130 | 75 | 146 | 98 |
Figure S34. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0351 (Fisher's exact test), Q value = 0.079
Table S35. Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 3Q GAIN MUTATED | 14 | 19 | 6 | 20 |
| 3Q GAIN WILD-TYPE | 134 | 83 | 94 | 138 |
Figure S35. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S36. Gene #6: '3q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 3Q GAIN MUTATED | 54 | 15 | 2 |
| 3Q GAIN WILD-TYPE | 479 | 527 | 13 |
Figure S36. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 5e-04 (Fisher's exact test), Q value = 0.0022
Table S37. Gene #6: '3q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 3Q GAIN MUTATED | 15 | 3 | 1 | 2 |
| 3Q GAIN WILD-TYPE | 169 | 234 | 63 | 163 |
Figure S37. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0462 (Fisher's exact test), Q value = 0.099
Table S38. Gene #6: '3q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 3Q GAIN MUTATED | 7 | 3 | 13 |
| 3Q GAIN WILD-TYPE | 217 | 201 | 205 |
Figure S38. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S39. Gene #6: '3q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 3Q GAIN MUTATED | 26 | 2 | 3 |
| 3Q GAIN WILD-TYPE | 207 | 233 | 189 |
Figure S39. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S40. Gene #6: '3q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 3Q GAIN MUTATED | 24 | 4 | 3 |
| 3Q GAIN WILD-TYPE | 179 | 186 | 264 |
Figure S40. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0428 (Fisher's exact test), Q value = 0.093
Table S41. Gene #7: '4p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 4P GAIN MUTATED | 7 | 7 | 2 | 0 |
| 4P GAIN WILD-TYPE | 177 | 230 | 62 | 165 |
Figure S41. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0404 (Fisher's exact test), Q value = 0.088
Table S42. Gene #7: '4p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 4P GAIN MUTATED | 15 | 5 | 5 |
| 4P GAIN WILD-TYPE | 219 | 249 | 153 |
Figure S42. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.00308 (Fisher's exact test), Q value = 0.011
Table S43. Gene #7: '4p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 4P GAIN MUTATED | 14 | 5 | 1 |
| 4P GAIN WILD-TYPE | 219 | 230 | 191 |
Figure S43. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0015
Table S44. Gene #7: '4p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 4P GAIN MUTATED | 13 | 6 | 1 |
| 4P GAIN WILD-TYPE | 190 | 184 | 266 |
Figure S44. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0442 (Fisher's exact test), Q value = 0.095
Table S45. Gene #7: '4p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 4P GAIN MUTATED | 3 | 3 | 6 |
| 4P GAIN WILD-TYPE | 219 | 181 | 97 |
Figure S45. Get High-res Image Gene #7: '4p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0284 (Fisher's exact test), Q value = 0.068
Table S46. Gene #8: '4q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 4Q GAIN MUTATED | 27 | 12 | 1 |
| 4Q GAIN WILD-TYPE | 506 | 530 | 14 |
Figure S46. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00606 (Fisher's exact test), Q value = 0.019
Table S47. Gene #8: '4q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 4Q GAIN MUTATED | 8 | 2 | 2 | 0 |
| 4Q GAIN WILD-TYPE | 176 | 235 | 62 | 165 |
Figure S47. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S48. Gene #8: '4q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 4Q GAIN MUTATED | 13 | 0 | 1 |
| 4Q GAIN WILD-TYPE | 220 | 235 | 191 |
Figure S48. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00035
Table S49. Gene #8: '4q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 4Q GAIN MUTATED | 12 | 1 | 1 |
| 4Q GAIN WILD-TYPE | 191 | 189 | 266 |
Figure S49. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S50. Gene #9: '5p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 5P GAIN MUTATED | 46 | 12 | 2 |
| 5P GAIN WILD-TYPE | 487 | 530 | 13 |
Figure S50. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0058 (Fisher's exact test), Q value = 0.018
Table S51. Gene #9: '5p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 5P GAIN MUTATED | 9 | 4 | 3 | 0 |
| 5P GAIN WILD-TYPE | 175 | 233 | 61 | 165 |
Figure S51. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00813 (Fisher's exact test), Q value = 0.024
Table S52. Gene #9: '5p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 5P GAIN MUTATED | 6 | 12 | 0 |
| 5P GAIN WILD-TYPE | 228 | 242 | 158 |
Figure S52. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S53. Gene #9: '5p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 5P GAIN MUTATED | 18 | 2 | 1 |
| 5P GAIN WILD-TYPE | 215 | 233 | 191 |
Figure S53. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S54. Gene #9: '5p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 5P GAIN MUTATED | 17 | 3 | 1 |
| 5P GAIN WILD-TYPE | 186 | 187 | 266 |
Figure S54. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0241 (Fisher's exact test), Q value = 0.06
Table S55. Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 5P GAIN MUTATED | 5 | 5 | 1 | 0 |
| 5P GAIN WILD-TYPE | 132 | 102 | 182 | 82 |
Figure S55. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.0278 (Fisher's exact test), Q value = 0.066
Table S56. Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 5P GAIN MUTATED | 3 | 2 | 6 |
| 5P GAIN WILD-TYPE | 219 | 182 | 97 |
Figure S56. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0159 (Fisher's exact test), Q value = 0.042
Table S57. Gene #9: '5p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 5P GAIN MUTATED | 1 | 3 | 1 | 6 |
| 5P GAIN WILD-TYPE | 90 | 134 | 187 | 83 |
Figure S57. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S58. Gene #10: '5q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 5Q GAIN MUTATED | 41 | 7 | 2 |
| 5Q GAIN WILD-TYPE | 492 | 535 | 13 |
Figure S58. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 6e-04 (Fisher's exact test), Q value = 0.0025
Table S59. Gene #10: '5q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 5Q GAIN MUTATED | 10 | 2 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 174 | 235 | 61 | 165 |
Figure S59. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0136 (Fisher's exact test), Q value = 0.037
Table S60. Gene #10: '5q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 5Q GAIN MUTATED | 4 | 10 | 0 |
| 5Q GAIN WILD-TYPE | 230 | 244 | 158 |
Figure S60. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S61. Gene #10: '5q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 5Q GAIN MUTATED | 17 | 1 | 1 |
| 5Q GAIN WILD-TYPE | 216 | 234 | 191 |
Figure S61. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S62. Gene #10: '5q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 5Q GAIN MUTATED | 17 | 1 | 1 |
| 5Q GAIN WILD-TYPE | 186 | 189 | 266 |
Figure S62. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00623 (Fisher's exact test), Q value = 0.019
Table S63. Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 5Q GAIN MUTATED | 2 | 1 | 6 |
| 5Q GAIN WILD-TYPE | 220 | 183 | 97 |
Figure S63. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0458 (Fisher's exact test), Q value = 0.098
Table S64. Gene #10: '5q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 5Q GAIN MUTATED | 7 | 1 | 1 |
| 5Q GAIN WILD-TYPE | 178 | 160 | 158 |
Figure S64. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.00478 (Fisher's exact test), Q value = 0.015
Table S65. Gene #10: '5q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 5Q GAIN MUTATED | 1 | 1 | 1 | 6 |
| 5Q GAIN WILD-TYPE | 90 | 136 | 187 | 83 |
Figure S65. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0161 (Fisher's exact test), Q value = 0.043
Table S66. Gene #11: '6p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 6P GAIN MUTATED | 4 | 10 | 3 | 4 |
| 6P GAIN WILD-TYPE | 143 | 86 | 149 | 109 |
Figure S66. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0229 (Fisher's exact test), Q value = 0.057
Table S67. Gene #11: '6p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 6P GAIN MUTATED | 6 | 9 | 0 | 0 |
| 6P GAIN WILD-TYPE | 178 | 228 | 64 | 165 |
Figure S67. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00966 (Fisher's exact test), Q value = 0.028
Table S68. Gene #11: '6p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 6P GAIN MUTATED | 4 | 1 | 11 |
| 6P GAIN WILD-TYPE | 220 | 203 | 207 |
Figure S68. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0111 (Fisher's exact test), Q value = 0.031
Table S69. Gene #11: '6p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 6P GAIN MUTATED | 4 | 5 | 0 | 1 |
| 6P GAIN WILD-TYPE | 133 | 102 | 183 | 81 |
Figure S69. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.0232 (Fisher's exact test), Q value = 0.058
Table S70. Gene #11: '6p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 6P GAIN MUTATED | 6 | 0 | 4 |
| 6P GAIN WILD-TYPE | 216 | 184 | 99 |
Figure S70. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00166 (Fisher's exact test), Q value = 0.006
Table S71. Gene #12: '6q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 6Q GAIN MUTATED | 4 | 11 | 2 | 3 |
| 6Q GAIN WILD-TYPE | 143 | 85 | 150 | 110 |
Figure S71. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0358 (Fisher's exact test), Q value = 0.08
Table S72. Gene #12: '6q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 6Q GAIN MUTATED | 5 | 7 | 0 | 8 |
| 6Q GAIN WILD-TYPE | 143 | 95 | 100 | 150 |
Figure S72. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0296 (Fisher's exact test), Q value = 0.07
Table S73. Gene #12: '6q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 6Q GAIN MUTATED | 16 | 10 | 2 |
| 6Q GAIN WILD-TYPE | 517 | 532 | 13 |
Figure S73. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00595 (Fisher's exact test), Q value = 0.018
Table S74. Gene #12: '6q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 6Q GAIN MUTATED | 0 | 4 | 0 | 1 |
| 6Q GAIN WILD-TYPE | 137 | 103 | 183 | 81 |
Figure S74. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S75. Gene #13: '7p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 7P GAIN MUTATED | 135 | 65 | 129 | 83 |
| 7P GAIN WILD-TYPE | 12 | 31 | 23 | 30 |
Figure S75. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S76. Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 7P GAIN MUTATED | 132 | 55 | 86 | 139 |
| 7P GAIN WILD-TYPE | 16 | 47 | 14 | 19 |
Figure S76. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00066 (Fisher's exact test), Q value = 0.0027
Table S77. Gene #13: '7p gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 7P GAIN MUTATED | 139 | 137 | 65 | 105 |
| 7P GAIN WILD-TYPE | 17 | 46 | 22 | 15 |
Figure S77. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S78. Gene #13: '7p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 7P GAIN MUTATED | 215 | 113 | 118 |
| 7P GAIN WILD-TYPE | 78 | 11 | 11 |
Figure S78. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S79. Gene #13: '7p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 7P GAIN MUTATED | 479 | 106 | 10 |
| 7P GAIN WILD-TYPE | 54 | 436 | 5 |
Figure S79. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S80. Gene #13: '7p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 7P GAIN MUTATED | 155 | 47 | 23 | 15 |
| 7P GAIN WILD-TYPE | 29 | 190 | 41 | 150 |
Figure S80. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S81. Gene #13: '7p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 7P GAIN MUTATED | 98 | 64 | 117 |
| 7P GAIN WILD-TYPE | 126 | 140 | 101 |
Figure S81. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S82. Gene #13: '7p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 7P GAIN MUTATED | 117 | 116 | 46 |
| 7P GAIN WILD-TYPE | 117 | 138 | 112 |
Figure S82. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S83. Gene #13: '7p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 7P GAIN MUTATED | 168 | 39 | 38 |
| 7P GAIN WILD-TYPE | 65 | 196 | 154 |
Figure S83. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S84. Gene #13: '7p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 7P GAIN MUTATED | 166 | 31 | 48 |
| 7P GAIN WILD-TYPE | 37 | 159 | 219 |
Figure S84. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00294 (Fisher's exact test), Q value = 0.01
Table S85. Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 7P GAIN MUTATED | 43 | 34 | 32 | 14 |
| 7P GAIN WILD-TYPE | 94 | 73 | 151 | 68 |
Figure S85. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S86. Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 7P GAIN MUTATED | 40 | 28 | 55 |
| 7P GAIN WILD-TYPE | 182 | 156 | 48 |
Figure S86. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0012
Table S87. Gene #13: '7p gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 7P GAIN MUTATED | 63 | 25 | 34 |
| 7P GAIN WILD-TYPE | 122 | 136 | 125 |
Figure S87. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S88. Gene #13: '7p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 7P GAIN MUTATED | 14 | 22 | 35 | 51 |
| 7P GAIN WILD-TYPE | 77 | 115 | 153 | 38 |
Figure S88. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S89. Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 7Q GAIN MUTATED | 135 | 62 | 130 | 88 |
| 7Q GAIN WILD-TYPE | 12 | 34 | 22 | 25 |
Figure S89. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S90. Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 7Q GAIN MUTATED | 130 | 61 | 85 | 139 |
| 7Q GAIN WILD-TYPE | 18 | 41 | 15 | 19 |
Figure S90. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00231 (Fisher's exact test), Q value = 0.0083
Table S91. Gene #14: '7q gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 7Q GAIN MUTATED | 140 | 137 | 69 | 103 |
| 7Q GAIN WILD-TYPE | 16 | 46 | 18 | 17 |
Figure S91. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.00063
Table S92. Gene #14: '7q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 7Q GAIN MUTATED | 222 | 112 | 115 |
| 7Q GAIN WILD-TYPE | 71 | 12 | 14 |
Figure S92. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S93. Gene #14: '7q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 7Q GAIN MUTATED | 484 | 137 | 10 |
| 7Q GAIN WILD-TYPE | 49 | 405 | 5 |
Figure S93. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S94. Gene #14: '7q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 7Q GAIN MUTATED | 160 | 65 | 26 | 23 |
| 7Q GAIN WILD-TYPE | 24 | 172 | 38 | 142 |
Figure S94. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00371 (Fisher's exact test), Q value = 0.012
Table S95. Gene #14: '7q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 7Q GAIN MUTATED | 108 | 79 | 120 |
| 7Q GAIN WILD-TYPE | 116 | 125 | 98 |
Figure S95. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0112 (Fisher's exact test), Q value = 0.032
Table S96. Gene #14: '7q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 7Q GAIN MUTATED | 122 | 126 | 59 |
| 7Q GAIN WILD-TYPE | 112 | 128 | 99 |
Figure S96. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S97. Gene #14: '7q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 7Q GAIN MUTATED | 174 | 53 | 52 |
| 7Q GAIN WILD-TYPE | 59 | 182 | 140 |
Figure S97. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S98. Gene #14: '7q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 7Q GAIN MUTATED | 171 | 43 | 65 |
| 7Q GAIN WILD-TYPE | 32 | 147 | 202 |
Figure S98. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00817 (Fisher's exact test), Q value = 0.024
Table S99. Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 7Q GAIN MUTATED | 49 | 41 | 47 | 16 |
| 7Q GAIN WILD-TYPE | 88 | 66 | 136 | 66 |
Figure S99. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S100. Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 7Q GAIN MUTATED | 51 | 43 | 59 |
| 7Q GAIN WILD-TYPE | 171 | 141 | 44 |
Figure S100. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00077 (Fisher's exact test), Q value = 0.0031
Table S101. Gene #14: '7q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 7Q GAIN MUTATED | 71 | 32 | 49 |
| 7Q GAIN WILD-TYPE | 114 | 129 | 110 |
Figure S101. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S102. Gene #14: '7q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 7Q GAIN MUTATED | 19 | 29 | 49 | 55 |
| 7Q GAIN WILD-TYPE | 72 | 108 | 139 | 34 |
Figure S102. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00025
Table S103. Gene #15: '8p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 8P GAIN MUTATED | 7 | 18 | 6 | 17 |
| 8P GAIN WILD-TYPE | 140 | 78 | 146 | 96 |
Figure S103. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00062 (Fisher's exact test), Q value = 0.0026
Table S104. Gene #15: '8p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 8P GAIN MUTATED | 10 | 21 | 4 | 13 |
| 8P GAIN WILD-TYPE | 138 | 81 | 96 | 145 |
Figure S104. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00022 (Fisher's exact test), Q value = 0.001
Table S105. Gene #15: '8p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 8P GAIN MUTATED | 10 | 37 | 3 | 8 |
| 8P GAIN WILD-TYPE | 174 | 200 | 61 | 157 |
Figure S105. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0139 (Fisher's exact test), Q value = 0.038
Table S106. Gene #15: '8p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 8P GAIN MUTATED | 20 | 29 | 18 |
| 8P GAIN WILD-TYPE | 183 | 161 | 249 |
Figure S106. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S107. Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 8Q GAIN MUTATED | 7 | 20 | 7 | 20 |
| 8Q GAIN WILD-TYPE | 140 | 76 | 145 | 93 |
Figure S107. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S108. Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 8Q GAIN MUTATED | 9 | 26 | 4 | 15 |
| 8Q GAIN WILD-TYPE | 139 | 76 | 96 | 143 |
Figure S108. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0403 (Fisher's exact test), Q value = 0.088
Table S109. Gene #16: '8q gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 8Q GAIN MUTATED | 10 | 27 | 10 | 8 |
| 8Q GAIN WILD-TYPE | 146 | 156 | 77 | 112 |
Figure S109. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.0182 (Fisher's exact test), Q value = 0.047
Table S110. Gene #16: '8q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 8Q GAIN MUTATED | 44 | 72 | 2 |
| 8Q GAIN WILD-TYPE | 489 | 470 | 13 |
Figure S110. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S111. Gene #16: '8q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 8Q GAIN MUTATED | 11 | 46 | 4 | 8 |
| 8Q GAIN WILD-TYPE | 173 | 191 | 60 | 157 |
Figure S111. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00098 (Fisher's exact test), Q value = 0.0039
Table S112. Gene #16: '8q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 8Q GAIN MUTATED | 21 | 37 | 21 |
| 8Q GAIN WILD-TYPE | 182 | 153 | 246 |
Figure S112. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0353 (Fisher's exact test), Q value = 0.079
Table S113. Gene #16: '8q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 8Q GAIN MUTATED | 25 | 23 | 10 |
| 8Q GAIN WILD-TYPE | 160 | 138 | 149 |
Figure S113. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.0105 (Fisher's exact test), Q value = 0.03
Table S114. Gene #16: '8q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 8Q GAIN MUTATED | 20 | 13 | 19 | 6 |
| 8Q GAIN WILD-TYPE | 71 | 124 | 169 | 83 |
Figure S114. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00372 (Fisher's exact test), Q value = 0.012
Table S115. Gene #17: '9p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 9P GAIN MUTATED | 14 | 17 | 7 | 6 |
| 9P GAIN WILD-TYPE | 133 | 79 | 145 | 107 |
Figure S115. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0307 (Fisher's exact test), Q value = 0.072
Table S116. Gene #17: '9p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 9P GAIN MUTATED | 15 | 12 | 2 | 15 |
| 9P GAIN WILD-TYPE | 133 | 90 | 98 | 143 |
Figure S116. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S117. Gene #17: '9p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 9P GAIN MUTATED | 44 | 16 | 4 |
| 9P GAIN WILD-TYPE | 489 | 526 | 11 |
Figure S117. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0174 (Fisher's exact test), Q value = 0.046
Table S118. Gene #17: '9p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 9P GAIN MUTATED | 14 | 10 | 1 | 2 |
| 9P GAIN WILD-TYPE | 170 | 227 | 63 | 163 |
Figure S118. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00042 (Fisher's exact test), Q value = 0.0018
Table S119. Gene #17: '9p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 9P GAIN MUTATED | 23 | 7 | 4 |
| 9P GAIN WILD-TYPE | 210 | 228 | 188 |
Figure S119. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00054 (Fisher's exact test), Q value = 0.0023
Table S120. Gene #17: '9p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 9P GAIN MUTATED | 21 | 7 | 6 |
| 9P GAIN WILD-TYPE | 182 | 183 | 261 |
Figure S120. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0257 (Fisher's exact test), Q value = 0.063
Table S121. Gene #17: '9p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 9P GAIN MUTATED | 4 | 5 | 8 |
| 9P GAIN WILD-TYPE | 218 | 179 | 95 |
Figure S121. Get High-res Image Gene #17: '9p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S122. Gene #18: '9q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 9Q GAIN MUTATED | 64 | 28 | 4 |
| 9Q GAIN WILD-TYPE | 469 | 514 | 11 |
Figure S122. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0142 (Fisher's exact test), Q value = 0.038
Table S123. Gene #18: '9q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 9Q GAIN MUTATED | 17 | 16 | 2 | 3 |
| 9Q GAIN WILD-TYPE | 167 | 221 | 62 | 162 |
Figure S123. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S124. Gene #18: '9q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 9Q GAIN MUTATED | 28 | 10 | 5 |
| 9Q GAIN WILD-TYPE | 205 | 225 | 187 |
Figure S124. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00282 (Fisher's exact test), Q value = 0.0099
Table S125. Gene #18: '9q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 9Q GAIN MUTATED | 23 | 11 | 9 |
| 9Q GAIN WILD-TYPE | 180 | 179 | 258 |
Figure S125. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0106 (Fisher's exact test), Q value = 0.03
Table S126. Gene #18: '9q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 9Q GAIN MUTATED | 6 | 7 | 11 |
| 9Q GAIN WILD-TYPE | 216 | 177 | 92 |
Figure S126. Get High-res Image Gene #18: '9q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.001 (Fisher's exact test), Q value = 0.0039
Table S127. Gene #19: '10p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 10P GAIN MUTATED | 1 | 6 | 0 | 5 |
| 10P GAIN WILD-TYPE | 146 | 90 | 152 | 108 |
Figure S127. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00045
Table S128. Gene #19: '10p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 10P GAIN MUTATED | 2 | 9 | 0 | 1 |
| 10P GAIN WILD-TYPE | 146 | 93 | 100 | 157 |
Figure S128. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S129. Gene #19: '10p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 10P GAIN MUTATED | 2 | 68 | 0 |
| 10P GAIN WILD-TYPE | 531 | 474 | 15 |
Figure S129. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S130. Gene #19: '10p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 10P GAIN MUTATED | 0 | 56 | 2 | 0 |
| 10P GAIN WILD-TYPE | 184 | 181 | 62 | 165 |
Figure S130. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S131. Gene #19: '10p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 10P GAIN MUTATED | 8 | 38 | 13 |
| 10P GAIN WILD-TYPE | 225 | 197 | 179 |
Figure S131. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S132. Gene #19: '10p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 10P GAIN MUTATED | 2 | 43 | 14 |
| 10P GAIN WILD-TYPE | 201 | 147 | 253 |
Figure S132. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00475 (Fisher's exact test), Q value = 0.015
Table S133. Gene #19: '10p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 10P GAIN MUTATED | 20 | 15 | 14 | 7 |
| 10P GAIN WILD-TYPE | 71 | 122 | 174 | 82 |
Figure S133. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00139 (Fisher's exact test), Q value = 0.0052
Table S134. Gene #20: '10q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 10Q GAIN MUTATED | 0 | 9 | 0 | 0 |
| 10Q GAIN WILD-TYPE | 184 | 228 | 64 | 165 |
Figure S134. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0139 (Fisher's exact test), Q value = 0.038
Table S135. Gene #21: '11p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 11P GAIN MUTATED | 15 | 35 | 0 |
| 11P GAIN WILD-TYPE | 518 | 507 | 15 |
Figure S135. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00079
Table S136. Gene #21: '11p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 11P GAIN MUTATED | 3 | 12 | 1 | 20 |
| 11P GAIN WILD-TYPE | 181 | 225 | 63 | 145 |
Figure S136. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0118 (Fisher's exact test), Q value = 0.033
Table S137. Gene #21: '11p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 11P GAIN MUTATED | 6 | 9 | 25 |
| 11P GAIN WILD-TYPE | 197 | 181 | 242 |
Figure S137. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0115 (Fisher's exact test), Q value = 0.032
Table S138. Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11P GAIN MUTATED | 15 | 17 | 1 |
| 11P GAIN WILD-TYPE | 207 | 167 | 102 |
Figure S138. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00382 (Fisher's exact test), Q value = 0.013
Table S139. Gene #21: '11p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 11P GAIN MUTATED | 4 | 10 | 19 | 0 |
| 11P GAIN WILD-TYPE | 87 | 127 | 169 | 89 |
Figure S139. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S140. Gene #22: '11q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 11Q GAIN MUTATED | 11 | 63 | 0 |
| 11Q GAIN WILD-TYPE | 522 | 479 | 15 |
Figure S140. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S141. Gene #22: '11q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 11Q GAIN MUTATED | 4 | 32 | 1 | 24 |
| 11Q GAIN WILD-TYPE | 180 | 205 | 63 | 141 |
Figure S141. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0481 (Fisher's exact test), Q value = 0.1
Table S142. Gene #22: '11q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 11Q GAIN MUTATED | 29 | 17 | 10 |
| 11Q GAIN WILD-TYPE | 205 | 237 | 148 |
Figure S142. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00025
Table S143. Gene #22: '11q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 11Q GAIN MUTATED | 7 | 35 | 20 |
| 11Q GAIN WILD-TYPE | 226 | 200 | 172 |
Figure S143. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S144. Gene #22: '11q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 11Q GAIN MUTATED | 3 | 23 | 36 |
| 11Q GAIN WILD-TYPE | 200 | 167 | 231 |
Figure S144. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0376 (Fisher's exact test), Q value = 0.084
Table S145. Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11Q GAIN MUTATED | 31 | 23 | 5 |
| 11Q GAIN WILD-TYPE | 191 | 161 | 98 |
Figure S145. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0319 (Fisher's exact test), Q value = 0.073
Table S146. Gene #22: '11q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 11Q GAIN MUTATED | 11 | 18 | 27 | 3 |
| 11Q GAIN WILD-TYPE | 80 | 119 | 161 | 86 |
Figure S146. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00259 (Fisher's exact test), Q value = 0.0092
Table S147. Gene #23: '12p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 12P GAIN MUTATED | 15 | 25 | 1 | 4 |
| 12P GAIN WILD-TYPE | 169 | 212 | 63 | 161 |
Figure S147. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00655 (Fisher's exact test), Q value = 0.02
Table S148. Gene #23: '12p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 12P GAIN MUTATED | 9 | 11 | 25 |
| 12P GAIN WILD-TYPE | 215 | 193 | 193 |
Figure S148. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00473 (Fisher's exact test), Q value = 0.015
Table S149. Gene #23: '12p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 12P GAIN MUTATED | 23 | 21 | 5 |
| 12P GAIN WILD-TYPE | 210 | 214 | 187 |
Figure S149. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.0196 (Fisher's exact test), Q value = 0.05
Table S150. Gene #23: '12p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 12P GAIN MUTATED | 21 | 17 | 11 |
| 12P GAIN WILD-TYPE | 182 | 173 | 256 |
Figure S150. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0318 (Fisher's exact test), Q value = 0.073
Table S151. Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 12P GAIN MUTATED | 12 | 11 | 5 | 6 |
| 12P GAIN WILD-TYPE | 125 | 96 | 178 | 76 |
Figure S151. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00778 (Fisher's exact test), Q value = 0.023
Table S152. Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 12P GAIN MUTATED | 17 | 5 | 12 |
| 12P GAIN WILD-TYPE | 205 | 179 | 91 |
Figure S152. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.03
Table S153. Gene #24: '12q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 12Q GAIN MUTATED | 16 | 15 | 17 |
| 12Q GAIN WILD-TYPE | 277 | 109 | 112 |
Figure S153. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S154. Gene #24: '12q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 12Q GAIN MUTATED | 49 | 17 | 0 |
| 12Q GAIN WILD-TYPE | 484 | 525 | 15 |
Figure S154. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0403 (Fisher's exact test), Q value = 0.088
Table S155. Gene #24: '12q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 12Q GAIN MUTATED | 14 | 9 | 1 | 3 |
| 12Q GAIN WILD-TYPE | 170 | 228 | 63 | 162 |
Figure S155. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0014
Table S156. Gene #24: '12q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 12Q GAIN MUTATED | 3 | 7 | 20 |
| 12Q GAIN WILD-TYPE | 221 | 197 | 198 |
Figure S156. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00117 (Fisher's exact test), Q value = 0.0045
Table S157. Gene #24: '12q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 12Q GAIN MUTATED | 19 | 8 | 2 |
| 12Q GAIN WILD-TYPE | 214 | 227 | 190 |
Figure S157. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00139 (Fisher's exact test), Q value = 0.0052
Table S158. Gene #24: '12q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 12Q GAIN MUTATED | 18 | 6 | 5 |
| 12Q GAIN WILD-TYPE | 185 | 184 | 262 |
Figure S158. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.019 (Fisher's exact test), Q value = 0.049
Table S159. Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 12Q GAIN MUTATED | 7 | 4 | 1 | 5 |
| 12Q GAIN WILD-TYPE | 130 | 103 | 182 | 77 |
Figure S159. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00364 (Fisher's exact test), Q value = 0.012
Table S160. Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 12Q GAIN MUTATED | 6 | 2 | 9 |
| 12Q GAIN WILD-TYPE | 216 | 182 | 94 |
Figure S160. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0104 (Fisher's exact test), Q value = 0.03
Table S161. Gene #26: '14q gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 14Q GAIN MUTATED | 10 | 4 | 7 | 1 |
| 14Q GAIN WILD-TYPE | 146 | 179 | 80 | 119 |
Figure S161. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00024 (Fisher's exact test), Q value = 0.0011
Table S162. Gene #26: '14q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 14Q GAIN MUTATED | 20 | 4 | 2 |
| 14Q GAIN WILD-TYPE | 513 | 538 | 13 |
Figure S162. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0261 (Fisher's exact test), Q value = 0.063
Table S163. Gene #27: '15q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 15Q GAIN MUTATED | 5 | 9 | 0 | 0 |
| 15Q GAIN WILD-TYPE | 179 | 228 | 64 | 165 |
Figure S163. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0461 (Fisher's exact test), Q value = 0.099
Table S164. Gene #27: '15q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 15Q GAIN MUTATED | 8 | 1 | 8 |
| 15Q GAIN WILD-TYPE | 216 | 203 | 210 |
Figure S164. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00304 (Fisher's exact test), Q value = 0.011
Table S165. Gene #27: '15q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 15Q GAIN MUTATED | 12 | 5 | 0 |
| 15Q GAIN WILD-TYPE | 222 | 249 | 158 |
Figure S165. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.0158 (Fisher's exact test), Q value = 0.042
Table S166. Gene #27: '15q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 15Q GAIN MUTATED | 13 | 5 | 2 |
| 15Q GAIN WILD-TYPE | 220 | 230 | 190 |
Figure S166. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00376 (Fisher's exact test), Q value = 0.012
Table S167. Gene #27: '15q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 15Q GAIN MUTATED | 12 | 6 | 2 |
| 15Q GAIN WILD-TYPE | 191 | 184 | 265 |
Figure S167. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0074 (Fisher's exact test), Q value = 0.022
Table S168. Gene #28: '16p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 16P GAIN MUTATED | 12 | 11 | 3 | 11 |
| 16P GAIN WILD-TYPE | 135 | 85 | 149 | 102 |
Figure S168. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0221 (Fisher's exact test), Q value = 0.056
Table S169. Gene #28: '16p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 16P GAIN MUTATED | 30 | 21 | 3 |
| 16P GAIN WILD-TYPE | 503 | 521 | 12 |
Figure S169. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0455 (Fisher's exact test), Q value = 0.098
Table S170. Gene #28: '16p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 16P GAIN MUTATED | 14 | 5 | 9 |
| 16P GAIN WILD-TYPE | 220 | 249 | 149 |
Figure S170. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.0476 (Fisher's exact test), Q value = 0.1
Table S171. Gene #28: '16p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 16P GAIN MUTATED | 12 | 3 | 8 |
| 16P GAIN WILD-TYPE | 221 | 232 | 184 |
Figure S171. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.0194 (Fisher's exact test), Q value = 0.05
Table S172. Gene #28: '16p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 16P GAIN MUTATED | 2 | 10 | 4 |
| 16P GAIN WILD-TYPE | 220 | 174 | 99 |
Figure S172. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.018 (Fisher's exact test), Q value = 0.047
Table S173. Gene #29: '16q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 16Q GAIN MUTATED | 10 | 12 | 4 | 10 |
| 16Q GAIN WILD-TYPE | 137 | 84 | 148 | 103 |
Figure S173. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00537 (Fisher's exact test), Q value = 0.017
Table S174. Gene #29: '16q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 16Q GAIN MUTATED | 10 | 15 | 2 | 9 |
| 16Q GAIN WILD-TYPE | 138 | 87 | 98 | 149 |
Figure S174. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.00079
Table S175. Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 17P GAIN MUTATED | 9 | 15 | 4 | 16 |
| 17P GAIN WILD-TYPE | 138 | 81 | 148 | 97 |
Figure S175. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.03
Table S176. Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 17P GAIN MUTATED | 9 | 17 | 4 | 14 |
| 17P GAIN WILD-TYPE | 139 | 85 | 96 | 144 |
Figure S176. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0193 (Fisher's exact test), Q value = 0.05
Table S177. Gene #30: '17p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 17P GAIN MUTATED | 34 | 8 | 5 |
| 17P GAIN WILD-TYPE | 259 | 116 | 124 |
Figure S177. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 0.00168 (Fisher's exact test), Q value = 0.0061
Table S178. Gene #30: '17p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 17P GAIN MUTATED | 48 | 22 | 2 |
| 17P GAIN WILD-TYPE | 485 | 520 | 13 |
Figure S178. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.017 (Fisher's exact test), Q value = 0.045
Table S179. Gene #30: '17p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 17P GAIN MUTATED | 10 | 4 | 17 |
| 17P GAIN WILD-TYPE | 214 | 200 | 201 |
Figure S179. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0413 (Fisher's exact test), Q value = 0.09
Table S180. Gene #30: '17p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 17P GAIN MUTATED | 17 | 12 | 4 |
| 17P GAIN WILD-TYPE | 216 | 223 | 188 |
Figure S180. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00103 (Fisher's exact test), Q value = 0.004
Table S181. Gene #31: '17q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 17Q GAIN MUTATED | 13 | 17 | 6 | 17 |
| 17Q GAIN WILD-TYPE | 134 | 79 | 146 | 96 |
Figure S181. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0467 (Fisher's exact test), Q value = 0.099
Table S182. Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 17Q GAIN MUTATED | 11 | 17 | 6 | 19 |
| 17Q GAIN WILD-TYPE | 137 | 85 | 94 | 139 |
Figure S182. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0311 (Fisher's exact test), Q value = 0.072
Table S183. Gene #31: '17q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 17Q GAIN MUTATED | 40 | 9 | 8 |
| 17Q GAIN WILD-TYPE | 253 | 115 | 121 |
Figure S183. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.00058
Table S184. Gene #31: '17q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 17Q GAIN MUTATED | 58 | 25 | 3 |
| 17Q GAIN WILD-TYPE | 475 | 517 | 12 |
Figure S184. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0394 (Fisher's exact test), Q value = 0.087
Table S185. Gene #31: '17q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 17Q GAIN MUTATED | 12 | 6 | 19 |
| 17Q GAIN WILD-TYPE | 212 | 198 | 199 |
Figure S185. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0015 (Fisher's exact test), Q value = 0.0056
Table S186. Gene #31: '17q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 17Q GAIN MUTATED | 24 | 15 | 4 |
| 17Q GAIN WILD-TYPE | 209 | 220 | 188 |
Figure S186. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.0274 (Fisher's exact test), Q value = 0.066
Table S187. Gene #31: '17q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 17Q GAIN MUTATED | 21 | 11 | 11 |
| 17Q GAIN WILD-TYPE | 182 | 179 | 256 |
Figure S187. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0255 (Fisher's exact test), Q value = 0.062
Table S188. Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 17Q GAIN MUTATED | 6 | 11 | 4 | 5 |
| 17Q GAIN WILD-TYPE | 131 | 96 | 179 | 77 |
Figure S188. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S189. Gene #32: '18p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 18P GAIN MUTATED | 10 | 25 | 5 | 15 |
| 18P GAIN WILD-TYPE | 137 | 71 | 147 | 98 |
Figure S189. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00053 (Fisher's exact test), Q value = 0.0023
Table S190. Gene #32: '18p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 18P GAIN MUTATED | 11 | 22 | 4 | 18 |
| 18P GAIN WILD-TYPE | 137 | 80 | 96 | 140 |
Figure S190. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00238 (Fisher's exact test), Q value = 0.0085
Table S191. Gene #32: '18p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 18P GAIN MUTATED | 46 | 28 | 4 |
| 18P GAIN WILD-TYPE | 487 | 514 | 11 |
Figure S191. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0157 (Fisher's exact test), Q value = 0.042
Table S192. Gene #32: '18p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 18P GAIN MUTATED | 11 | 14 | 2 | 1 |
| 18P GAIN WILD-TYPE | 173 | 223 | 62 | 164 |
Figure S192. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S193. Gene #32: '18p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 18P GAIN MUTATED | 26 | 7 | 4 |
| 18P GAIN WILD-TYPE | 207 | 228 | 188 |
Figure S193. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0014
Table S194. Gene #32: '18p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 18P GAIN MUTATED | 21 | 11 | 5 |
| 18P GAIN WILD-TYPE | 182 | 179 | 262 |
Figure S194. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0349 (Fisher's exact test), Q value = 0.079
Table S195. Gene #32: '18p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 18P GAIN MUTATED | 2 | 8 | 3 | 7 |
| 18P GAIN WILD-TYPE | 89 | 129 | 185 | 82 |
Figure S195. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S196. Gene #33: '18q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 18Q GAIN MUTATED | 9 | 24 | 6 | 17 |
| 18Q GAIN WILD-TYPE | 138 | 72 | 146 | 96 |
Figure S196. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00035 (Fisher's exact test), Q value = 0.0016
Table S197. Gene #33: '18q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 18Q GAIN MUTATED | 10 | 24 | 6 | 16 |
| 18Q GAIN WILD-TYPE | 138 | 78 | 94 | 142 |
Figure S197. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00054
Table S198. Gene #33: '18q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 18Q GAIN MUTATED | 49 | 22 | 4 |
| 18Q GAIN WILD-TYPE | 484 | 520 | 11 |
Figure S198. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00085 (Fisher's exact test), Q value = 0.0035
Table S199. Gene #33: '18q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 18Q GAIN MUTATED | 14 | 10 | 2 | 0 |
| 18Q GAIN WILD-TYPE | 170 | 227 | 62 | 165 |
Figure S199. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S200. Gene #33: '18q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 18Q GAIN MUTATED | 28 | 5 | 1 |
| 18Q GAIN WILD-TYPE | 205 | 230 | 191 |
Figure S200. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S201. Gene #33: '18q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 18Q GAIN MUTATED | 23 | 9 | 2 |
| 18Q GAIN WILD-TYPE | 180 | 181 | 265 |
Figure S201. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00977 (Fisher's exact test), Q value = 0.028
Table S202. Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 18Q GAIN MUTATED | 6 | 2 | 8 |
| 18Q GAIN WILD-TYPE | 216 | 182 | 95 |
Figure S202. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00086 (Fisher's exact test), Q value = 0.0035
Table S203. Gene #33: '18q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 18Q GAIN MUTATED | 1 | 6 | 1 | 8 |
| 18Q GAIN WILD-TYPE | 90 | 131 | 187 | 81 |
Figure S203. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S204. Gene #34: '19p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 19P GAIN MUTATED | 52 | 34 | 91 | 20 |
| 19P GAIN WILD-TYPE | 95 | 62 | 61 | 93 |
Figure S204. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S205. Gene #34: '19p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 19P GAIN MUTATED | 62 | 25 | 58 | 52 |
| 19P GAIN WILD-TYPE | 86 | 77 | 42 | 106 |
Figure S205. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00041 (Fisher's exact test), Q value = 0.0018
Table S206. Gene #34: '19p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 19P GAIN MUTATED | 94 | 49 | 68 |
| 19P GAIN WILD-TYPE | 199 | 75 | 61 |
Figure S206. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S207. Gene #34: '19p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 19P GAIN MUTATED | 235 | 82 | 6 |
| 19P GAIN WILD-TYPE | 298 | 460 | 9 |
Figure S207. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S208. Gene #34: '19p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 19P GAIN MUTATED | 72 | 12 | 6 | 57 |
| 19P GAIN WILD-TYPE | 112 | 225 | 58 | 108 |
Figure S208. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0179 (Fisher's exact test), Q value = 0.046
Table S209. Gene #34: '19p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 19P GAIN MUTATED | 62 | 39 | 67 |
| 19P GAIN WILD-TYPE | 162 | 165 | 151 |
Figure S209. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00117 (Fisher's exact test), Q value = 0.0045
Table S210. Gene #34: '19p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 19P GAIN MUTATED | 62 | 81 | 25 |
| 19P GAIN WILD-TYPE | 172 | 173 | 133 |
Figure S210. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S211. Gene #34: '19p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 19P GAIN MUTATED | 77 | 31 | 39 |
| 19P GAIN WILD-TYPE | 156 | 204 | 153 |
Figure S211. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S212. Gene #34: '19p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 19P GAIN MUTATED | 72 | 12 | 63 |
| 19P GAIN WILD-TYPE | 131 | 178 | 204 |
Figure S212. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00147 (Fisher's exact test), Q value = 0.0055
Table S213. Gene #34: '19p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 19P GAIN MUTATED | 19 | 17 | 33 | 29 |
| 19P GAIN WILD-TYPE | 118 | 90 | 150 | 53 |
Figure S213. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.0303 (Fisher's exact test), Q value = 0.071
Table S214. Gene #34: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 19P GAIN MUTATED | 33 | 37 | 28 |
| 19P GAIN WILD-TYPE | 189 | 147 | 75 |
Figure S214. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0075 (Fisher's exact test), Q value = 0.023
Table S215. Gene #34: '19p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 19P GAIN MUTATED | 9 | 30 | 33 | 26 |
| 19P GAIN WILD-TYPE | 82 | 107 | 155 | 63 |
Figure S215. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S216. Gene #35: '19q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 19Q GAIN MUTATED | 46 | 27 | 83 | 14 |
| 19Q GAIN WILD-TYPE | 101 | 69 | 69 | 99 |
Figure S216. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S217. Gene #35: '19q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 19Q GAIN MUTATED | 55 | 18 | 54 | 43 |
| 19Q GAIN WILD-TYPE | 93 | 84 | 46 | 115 |
Figure S217. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00974 (Fisher's exact test), Q value = 0.028
Table S218. Gene #35: '19q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 19Q GAIN MUTATED | 82 | 45 | 55 |
| 19Q GAIN WILD-TYPE | 211 | 79 | 74 |
Figure S218. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S219. Gene #35: '19q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 19Q GAIN MUTATED | 204 | 12 | 6 |
| 19Q GAIN WILD-TYPE | 329 | 530 | 9 |
Figure S219. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S220. Gene #35: '19q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 19Q GAIN MUTATED | 59 | 3 | 5 | 0 |
| 19Q GAIN WILD-TYPE | 125 | 234 | 59 | 165 |
Figure S220. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00608 (Fisher's exact test), Q value = 0.019
Table S221. Gene #35: '19q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 19Q GAIN MUTATED | 30 | 45 | 11 |
| 19Q GAIN WILD-TYPE | 204 | 209 | 147 |
Figure S221. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S222. Gene #35: '19q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 19Q GAIN MUTATED | 66 | 1 | 5 |
| 19Q GAIN WILD-TYPE | 167 | 234 | 187 |
Figure S222. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S223. Gene #35: '19q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 19Q GAIN MUTATED | 64 | 4 | 4 |
| 19Q GAIN WILD-TYPE | 139 | 186 | 263 |
Figure S223. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00093 (Fisher's exact test), Q value = 0.0037
Table S224. Gene #35: '19q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 19Q GAIN MUTATED | 8 | 13 | 6 | 0 |
| 19Q GAIN WILD-TYPE | 129 | 94 | 177 | 82 |
Figure S224. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S225. Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 19Q GAIN MUTATED | 4 | 2 | 21 |
| 19Q GAIN WILD-TYPE | 218 | 182 | 82 |
Figure S225. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S226. Gene #35: '19q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 19Q GAIN MUTATED | 21 | 1 | 5 |
| 19Q GAIN WILD-TYPE | 164 | 160 | 154 |
Figure S226. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S227. Gene #35: '19q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 19Q GAIN MUTATED | 3 | 0 | 2 | 22 |
| 19Q GAIN WILD-TYPE | 88 | 137 | 186 | 67 |
Figure S227. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S228. Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 20P GAIN MUTATED | 51 | 26 | 86 | 29 |
| 20P GAIN WILD-TYPE | 96 | 70 | 66 | 84 |
Figure S228. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S229. Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 20P GAIN MUTATED | 55 | 21 | 64 | 52 |
| 20P GAIN WILD-TYPE | 93 | 81 | 36 | 106 |
Figure S229. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00431 (Fisher's exact test), Q value = 0.014
Table S230. Gene #36: '20p gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 20P GAIN MUTATED | 61 | 75 | 20 | 56 |
| 20P GAIN WILD-TYPE | 95 | 108 | 67 | 64 |
Figure S230. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S231. Gene #36: '20p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 20P GAIN MUTATED | 85 | 58 | 69 |
| 20P GAIN WILD-TYPE | 208 | 66 | 60 |
Figure S231. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S232. Gene #36: '20p gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 20P GAIN MUTATED | 224 | 39 | 3 |
| 20P GAIN WILD-TYPE | 309 | 503 | 12 |
Figure S232. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S233. Gene #36: '20p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 20P GAIN MUTATED | 69 | 9 | 5 | 7 |
| 20P GAIN WILD-TYPE | 115 | 228 | 59 | 158 |
Figure S233. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00155 (Fisher's exact test), Q value = 0.0057
Table S234. Gene #36: '20p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 20P GAIN MUTATED | 43 | 21 | 50 |
| 20P GAIN WILD-TYPE | 181 | 183 | 168 |
Figure S234. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S235. Gene #36: '20p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 20P GAIN MUTATED | 46 | 58 | 10 |
| 20P GAIN WILD-TYPE | 188 | 196 | 148 |
Figure S235. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S236. Gene #36: '20p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 20P GAIN MUTATED | 75 | 8 | 14 |
| 20P GAIN WILD-TYPE | 158 | 227 | 178 |
Figure S236. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S237. Gene #36: '20p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 20P GAIN MUTATED | 73 | 9 | 15 |
| 20P GAIN WILD-TYPE | 130 | 181 | 252 |
Figure S237. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S238. Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 20P GAIN MUTATED | 8 | 10 | 26 |
| 20P GAIN WILD-TYPE | 214 | 174 | 77 |
Figure S238. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00247 (Fisher's exact test), Q value = 0.0088
Table S239. Gene #36: '20p gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 20P GAIN MUTATED | 26 | 6 | 12 |
| 20P GAIN WILD-TYPE | 159 | 155 | 147 |
Figure S239. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S240. Gene #36: '20p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 20P GAIN MUTATED | 3 | 5 | 10 | 26 |
| 20P GAIN WILD-TYPE | 88 | 132 | 178 | 63 |
Figure S240. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S241. Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 20Q GAIN MUTATED | 50 | 28 | 86 | 27 |
| 20Q GAIN WILD-TYPE | 97 | 68 | 66 | 86 |
Figure S241. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S242. Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 20Q GAIN MUTATED | 58 | 22 | 62 | 49 |
| 20Q GAIN WILD-TYPE | 90 | 80 | 38 | 109 |
Figure S242. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00276 (Fisher's exact test), Q value = 0.0097
Table S243. Gene #37: '20q gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 20Q GAIN MUTATED | 62 | 74 | 19 | 55 |
| 20Q GAIN WILD-TYPE | 94 | 109 | 68 | 65 |
Figure S243. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S244. Gene #37: '20q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 20Q GAIN MUTATED | 85 | 57 | 68 |
| 20Q GAIN WILD-TYPE | 208 | 67 | 61 |
Figure S244. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S245. Gene #37: '20q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 20Q GAIN MUTATED | 223 | 37 | 3 |
| 20Q GAIN WILD-TYPE | 310 | 505 | 12 |
Figure S245. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S246. Gene #37: '20q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 20Q GAIN MUTATED | 70 | 8 | 5 | 6 |
| 20Q GAIN WILD-TYPE | 114 | 229 | 59 | 159 |
Figure S246. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0015
Table S247. Gene #37: '20q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 20Q GAIN MUTATED | 45 | 19 | 50 |
| 20Q GAIN WILD-TYPE | 179 | 185 | 168 |
Figure S247. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S248. Gene #37: '20q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 20Q GAIN MUTATED | 46 | 59 | 9 |
| 20Q GAIN WILD-TYPE | 188 | 195 | 149 |
Figure S248. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S249. Gene #37: '20q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 20Q GAIN MUTATED | 77 | 7 | 12 |
| 20Q GAIN WILD-TYPE | 156 | 228 | 180 |
Figure S249. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S250. Gene #37: '20q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 20Q GAIN MUTATED | 74 | 9 | 13 |
| 20Q GAIN WILD-TYPE | 129 | 181 | 254 |
Figure S250. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0254 (Fisher's exact test), Q value = 0.062
Table S251. Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 20Q GAIN MUTATED | 17 | 13 | 10 | 3 |
| 20Q GAIN WILD-TYPE | 120 | 94 | 173 | 79 |
Figure S251. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S252. Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 20Q GAIN MUTATED | 9 | 8 | 26 |
| 20Q GAIN WILD-TYPE | 213 | 176 | 77 |
Figure S252. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00019 (Fisher's exact test), Q value = 0.00092
Table S253. Gene #37: '20q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 20Q GAIN MUTATED | 28 | 5 | 10 |
| 20Q GAIN WILD-TYPE | 157 | 156 | 149 |
Figure S253. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S254. Gene #37: '20q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 20Q GAIN MUTATED | 6 | 4 | 7 | 26 |
| 20Q GAIN WILD-TYPE | 85 | 133 | 181 | 63 |
Figure S254. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00117 (Fisher's exact test), Q value = 0.0045
Table S255. Gene #38: '21q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 21Q GAIN MUTATED | 28 | 11 | 9 | 7 |
| 21Q GAIN WILD-TYPE | 119 | 85 | 143 | 106 |
Figure S255. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00755 (Fisher's exact test), Q value = 0.023
Table S256. Gene #38: '21q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 21Q GAIN MUTATED | 25 | 6 | 5 | 19 |
| 21Q GAIN WILD-TYPE | 123 | 96 | 95 | 139 |
Figure S256. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0114 (Fisher's exact test), Q value = 0.032
Table S257. Gene #38: '21q gain' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 21Q GAIN MUTATED | 24 | 15 | 4 | 19 |
| 21Q GAIN WILD-TYPE | 132 | 168 | 83 | 101 |
Figure S257. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00375 (Fisher's exact test), Q value = 0.012
Table S258. Gene #38: '21q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 21Q GAIN MUTATED | 26 | 25 | 11 |
| 21Q GAIN WILD-TYPE | 267 | 99 | 118 |
Figure S258. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S259. Gene #38: '21q gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 21Q GAIN MUTATED | 63 | 24 | 1 |
| 21Q GAIN WILD-TYPE | 470 | 518 | 14 |
Figure S259. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0203 (Fisher's exact test), Q value = 0.051
Table S260. Gene #38: '21q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 21Q GAIN MUTATED | 17 | 6 | 2 | 9 |
| 21Q GAIN WILD-TYPE | 167 | 231 | 62 | 156 |
Figure S260. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.0011
Table S261. Gene #38: '21q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 21Q GAIN MUTATED | 30 | 8 | 9 |
| 21Q GAIN WILD-TYPE | 203 | 227 | 183 |
Figure S261. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S262. Gene #38: '21q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 21Q GAIN MUTATED | 30 | 5 | 12 |
| 21Q GAIN WILD-TYPE | 173 | 185 | 255 |
Figure S262. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S263. Gene #39: '22q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 22Q GAIN MUTATED | 5 | 14 | 0 | 10 |
| 22Q GAIN WILD-TYPE | 142 | 82 | 152 | 103 |
Figure S263. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00649 (Fisher's exact test), Q value = 0.02
Table S264. Gene #39: '22q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 22Q GAIN MUTATED | 10 | 10 | 0 | 9 |
| 22Q GAIN WILD-TYPE | 138 | 92 | 100 | 149 |
Figure S264. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S265. Gene #39: '22q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 22Q GAIN MUTATED | 7 | 2 | 0 | 18 |
| 22Q GAIN WILD-TYPE | 177 | 235 | 64 | 147 |
Figure S265. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0136 (Fisher's exact test), Q value = 0.037
Table S266. Gene #39: '22q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 22Q GAIN MUTATED | 13 | 3 | 19 |
| 22Q GAIN WILD-TYPE | 190 | 187 | 248 |
Figure S266. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0406 (Fisher's exact test), Q value = 0.089
Table S267. Gene #39: '22q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 22Q GAIN MUTATED | 3 | 10 | 10 |
| 22Q GAIN WILD-TYPE | 182 | 151 | 149 |
Figure S267. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00058
Table S268. Gene #40: 'xp gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| XP GAIN MUTATED | 5 | 18 | 0 | 0 |
| XP GAIN WILD-TYPE | 179 | 219 | 64 | 165 |
Figure S268. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00351 (Fisher's exact test), Q value = 0.012
Table S269. Gene #41: 'xq gain' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| XQ GAIN MUTATED | 17 | 42 | 0 |
| XQ GAIN WILD-TYPE | 516 | 500 | 15 |
Figure S269. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S270. Gene #41: 'xq gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| XQ GAIN MUTATED | 6 | 36 | 3 | 0 |
| XQ GAIN WILD-TYPE | 178 | 201 | 61 | 165 |
Figure S270. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0424 (Fisher's exact test), Q value = 0.092
Table S271. Gene #41: 'xq gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| XQ GAIN MUTATED | 11 | 25 | 12 |
| XQ GAIN WILD-TYPE | 222 | 210 | 180 |
Figure S271. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00071 (Fisher's exact test), Q value = 0.0029
Table S272. Gene #41: 'xq gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| XQ GAIN MUTATED | 9 | 26 | 13 |
| XQ GAIN WILD-TYPE | 194 | 164 | 254 |
Figure S272. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0226 (Fisher's exact test), Q value = 0.057
Table S273. Gene #41: 'xq gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| XQ GAIN MUTATED | 15 | 7 | 14 | 5 |
| XQ GAIN WILD-TYPE | 76 | 130 | 174 | 84 |
Figure S273. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S274. Gene #42: '1p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 1P LOSS MUTATED | 16 | 183 | 0 |
| 1P LOSS WILD-TYPE | 517 | 359 | 15 |
Figure S274. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S275. Gene #42: '1p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 1P LOSS MUTATED | 7 | 6 | 13 | 161 |
| 1P LOSS WILD-TYPE | 177 | 231 | 51 | 4 |
Figure S275. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0032 (Fisher's exact test), Q value = 0.011
Table S276. Gene #42: '1p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 1P LOSS MUTATED | 50 | 70 | 46 |
| 1P LOSS WILD-TYPE | 174 | 134 | 172 |
Figure S276. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S277. Gene #42: '1p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 1P LOSS MUTATED | 53 | 49 | 64 |
| 1P LOSS WILD-TYPE | 181 | 205 | 94 |
Figure S277. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S278. Gene #42: '1p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 1P LOSS MUTATED | 10 | 80 | 97 |
| 1P LOSS WILD-TYPE | 223 | 155 | 95 |
Figure S278. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S279. Gene #42: '1p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 1P LOSS MUTATED | 6 | 11 | 170 |
| 1P LOSS WILD-TYPE | 197 | 179 | 97 |
Figure S279. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S280. Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 1P LOSS MUTATED | 26 | 9 | 83 | 65 |
| 1P LOSS WILD-TYPE | 111 | 98 | 100 | 17 |
Figure S280. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S281. Gene #42: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 1P LOSS MUTATED | 80 | 96 | 7 |
| 1P LOSS WILD-TYPE | 142 | 88 | 96 |
Figure S281. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S282. Gene #42: '1p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 1P LOSS MUTATED | 30 | 81 | 72 |
| 1P LOSS WILD-TYPE | 155 | 80 | 87 |
Figure S282. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S283. Gene #42: '1p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 1P LOSS MUTATED | 7 | 81 | 88 | 7 |
| 1P LOSS WILD-TYPE | 84 | 56 | 100 | 82 |
Figure S283. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0196 (Fisher's exact test), Q value = 0.05
Table S284. Gene #43: '1q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 1Q LOSS MUTATED | 6 | 7 | 5 | 15 |
| 1Q LOSS WILD-TYPE | 178 | 230 | 59 | 150 |
Figure S284. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0402 (Fisher's exact test), Q value = 0.088
Table S285. Gene #43: '1q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 1Q LOSS MUTATED | 6 | 7 | 21 |
| 1Q LOSS WILD-TYPE | 197 | 183 | 246 |
Figure S285. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0299 (Fisher's exact test), Q value = 0.071
Table S286. Gene #44: '2p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 2P LOSS MUTATED | 7 | 12 | 5 | 5 |
| 2P LOSS WILD-TYPE | 140 | 84 | 147 | 108 |
Figure S286. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0287 (Fisher's exact test), Q value = 0.068
Table S287. Gene #44: '2p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 2P LOSS MUTATED | 8 | 12 | 2 | 7 |
| 2P LOSS WILD-TYPE | 140 | 90 | 98 | 151 |
Figure S287. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0245 (Fisher's exact test), Q value = 0.06
Table S288. Gene #44: '2p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 2P LOSS MUTATED | 11 | 17 | 2 | 2 |
| 2P LOSS WILD-TYPE | 173 | 220 | 62 | 163 |
Figure S288. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0464 (Fisher's exact test), Q value = 0.099
Table S289. Gene #44: '2p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 2P LOSS MUTATED | 10 | 13 | 6 |
| 2P LOSS WILD-TYPE | 193 | 177 | 261 |
Figure S289. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.034 (Fisher's exact test), Q value = 0.077
Table S290. Gene #45: '2q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 2Q LOSS MUTATED | 7 | 12 | 5 | 6 |
| 2Q LOSS WILD-TYPE | 140 | 84 | 147 | 107 |
Figure S290. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0132 (Fisher's exact test), Q value = 0.036
Table S291. Gene #45: '2q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 2Q LOSS MUTATED | 8 | 13 | 2 | 7 |
| 2Q LOSS WILD-TYPE | 140 | 89 | 98 | 151 |
Figure S291. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0199 (Fisher's exact test), Q value = 0.051
Table S292. Gene #45: '2q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 2Q LOSS MUTATED | 9 | 17 | 1 | 2 |
| 2Q LOSS WILD-TYPE | 175 | 220 | 63 | 163 |
Figure S292. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0332 (Fisher's exact test), Q value = 0.076
Table S293. Gene #45: '2q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 2Q LOSS MUTATED | 4 | 9 | 3 | 2 |
| 2Q LOSS WILD-TYPE | 133 | 98 | 180 | 80 |
Figure S293. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.0391 (Fisher's exact test), Q value = 0.087
Table S294. Gene #46: '3p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 3P LOSS MUTATED | 13 | 9 | 23 |
| 3P LOSS WILD-TYPE | 211 | 195 | 195 |
Figure S294. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0333 (Fisher's exact test), Q value = 0.076
Table S295. Gene #46: '3p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 3P LOSS MUTATED | 23 | 17 | 5 |
| 3P LOSS WILD-TYPE | 211 | 237 | 153 |
Figure S295. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.0258 (Fisher's exact test), Q value = 0.063
Table S296. Gene #46: '3p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 3P LOSS MUTATED | 20 | 15 | 5 |
| 3P LOSS WILD-TYPE | 213 | 220 | 187 |
Figure S296. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.0425 (Fisher's exact test), Q value = 0.092
Table S297. Gene #46: '3p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 3P LOSS MUTATED | 17 | 14 | 9 |
| 3P LOSS WILD-TYPE | 186 | 176 | 258 |
Figure S297. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00088 (Fisher's exact test), Q value = 0.0036
Table S298. Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 3P LOSS MUTATED | 9 | 14 | 3 | 4 |
| 3P LOSS WILD-TYPE | 128 | 93 | 180 | 78 |
Figure S298. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0022
Table S299. Gene #46: '3p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 3P LOSS MUTATED | 18 | 2 | 10 |
| 3P LOSS WILD-TYPE | 204 | 182 | 93 |
Figure S299. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00274 (Fisher's exact test), Q value = 0.0097
Table S300. Gene #46: '3p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 3P LOSS MUTATED | 11 | 6 | 4 | 8 |
| 3P LOSS WILD-TYPE | 80 | 131 | 184 | 81 |
Figure S300. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0341 (Fisher's exact test), Q value = 0.077
Table S301. Gene #47: '3q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 3Q LOSS MUTATED | 12 | 16 | 8 |
| 3Q LOSS WILD-TYPE | 191 | 174 | 259 |
Figure S301. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.048 (Fisher's exact test), Q value = 0.1
Table S302. Gene #47: '3q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 3Q LOSS MUTATED | 8 | 12 | 6 | 3 |
| 3Q LOSS WILD-TYPE | 129 | 95 | 177 | 79 |
Figure S302. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.0124 (Fisher's exact test), Q value = 0.034
Table S303. Gene #47: '3q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 3Q LOSS MUTATED | 15 | 4 | 10 |
| 3Q LOSS WILD-TYPE | 207 | 180 | 93 |
Figure S303. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0319 (Fisher's exact test), Q value = 0.073
Table S304. Gene #47: '3q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 3Q LOSS MUTATED | 9 | 9 | 4 | 6 |
| 3Q LOSS WILD-TYPE | 82 | 128 | 184 | 83 |
Figure S304. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0469 (Fisher's exact test), Q value = 0.099
Table S305. Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 4P LOSS MUTATED | 11 | 17 | 11 | 12 |
| 4P LOSS WILD-TYPE | 136 | 79 | 141 | 101 |
Figure S305. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00159 (Fisher's exact test), Q value = 0.0058
Table S306. Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 4P LOSS MUTATED | 10 | 20 | 4 | 17 |
| 4P LOSS WILD-TYPE | 138 | 82 | 96 | 141 |
Figure S306. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0153 (Fisher's exact test), Q value = 0.041
Table S307. Gene #48: '4p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 4P LOSS MUTATED | 48 | 76 | 3 |
| 4P LOSS WILD-TYPE | 485 | 466 | 12 |
Figure S307. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S308. Gene #48: '4p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 4P LOSS MUTATED | 13 | 25 | 0 | 45 |
| 4P LOSS WILD-TYPE | 171 | 212 | 64 | 120 |
Figure S308. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00156 (Fisher's exact test), Q value = 0.0057
Table S309. Gene #48: '4p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 4P LOSS MUTATED | 20 | 19 | 53 |
| 4P LOSS WILD-TYPE | 183 | 171 | 214 |
Figure S309. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00035
Table S310. Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 4P LOSS MUTATED | 11 | 12 | 22 | 26 |
| 4P LOSS WILD-TYPE | 126 | 95 | 161 | 56 |
Figure S310. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00033 (Fisher's exact test), Q value = 0.0015
Table S311. Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 4P LOSS MUTATED | 38 | 30 | 3 |
| 4P LOSS WILD-TYPE | 184 | 154 | 100 |
Figure S311. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S312. Gene #48: '4p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 4P LOSS MUTATED | 10 | 35 | 26 |
| 4P LOSS WILD-TYPE | 175 | 126 | 133 |
Figure S312. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S313. Gene #48: '4p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 4P LOSS MUTATED | 6 | 34 | 29 | 2 |
| 4P LOSS WILD-TYPE | 85 | 103 | 159 | 87 |
Figure S313. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00017 (Fisher's exact test), Q value = 0.00083
Table S314. Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 4Q LOSS MUTATED | 10 | 21 | 7 | 13 |
| 4Q LOSS WILD-TYPE | 137 | 75 | 145 | 100 |
Figure S314. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.00096
Table S315. Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 4Q LOSS MUTATED | 10 | 22 | 3 | 16 |
| 4Q LOSS WILD-TYPE | 138 | 80 | 97 | 142 |
Figure S315. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0302 (Fisher's exact test), Q value = 0.071
Table S316. Gene #49: '4q loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 4Q LOSS MUTATED | 7 | 25 | 9 | 13 |
| 4Q LOSS WILD-TYPE | 149 | 158 | 78 | 107 |
Figure S316. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S317. Gene #49: '4q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 4Q LOSS MUTATED | 46 | 102 | 3 |
| 4Q LOSS WILD-TYPE | 487 | 440 | 12 |
Figure S317. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S318. Gene #49: '4q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 4Q LOSS MUTATED | 14 | 44 | 3 | 48 |
| 4Q LOSS WILD-TYPE | 170 | 193 | 61 | 117 |
Figure S318. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00942 (Fisher's exact test), Q value = 0.027
Table S319. Gene #49: '4q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 4Q LOSS MUTATED | 27 | 51 | 37 |
| 4Q LOSS WILD-TYPE | 206 | 184 | 155 |
Figure S319. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00079
Table S320. Gene #49: '4q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 4Q LOSS MUTATED | 20 | 30 | 65 |
| 4Q LOSS WILD-TYPE | 183 | 160 | 202 |
Figure S320. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00067
Table S321. Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 4Q LOSS MUTATED | 12 | 19 | 35 | 27 |
| 4Q LOSS WILD-TYPE | 125 | 88 | 148 | 55 |
Figure S321. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00381 (Fisher's exact test), Q value = 0.013
Table S322. Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 4Q LOSS MUTATED | 44 | 41 | 8 |
| 4Q LOSS WILD-TYPE | 178 | 143 | 95 |
Figure S322. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S323. Gene #49: '4q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 4Q LOSS MUTATED | 14 | 43 | 36 |
| 4Q LOSS WILD-TYPE | 171 | 118 | 123 |
Figure S323. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S324. Gene #49: '4q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 4Q LOSS MUTATED | 9 | 39 | 39 | 6 |
| 4Q LOSS WILD-TYPE | 82 | 98 | 149 | 83 |
Figure S324. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S325. Gene #50: '5p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 5P LOSS MUTATED | 5 | 21 | 6 | 9 |
| 5P LOSS WILD-TYPE | 142 | 75 | 146 | 104 |
Figure S325. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S326. Gene #50: '5p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 5P LOSS MUTATED | 6 | 23 | 5 | 7 |
| 5P LOSS WILD-TYPE | 142 | 79 | 95 | 151 |
Figure S326. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00096 (Fisher's exact test), Q value = 0.0038
Table S327. Gene #50: '5p loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 5P LOSS MUTATED | 4 | 25 | 6 | 6 |
| 5P LOSS WILD-TYPE | 152 | 158 | 81 | 114 |
Figure S327. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.0022
Table S328. Gene #50: '5p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 5P LOSS MUTATED | 25 | 50 | 4 |
| 5P LOSS WILD-TYPE | 508 | 492 | 11 |
Figure S328. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S329. Gene #50: '5p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 5P LOSS MUTATED | 12 | 29 | 2 | 2 |
| 5P LOSS WILD-TYPE | 172 | 208 | 62 | 163 |
Figure S329. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0448 (Fisher's exact test), Q value = 0.096
Table S330. Gene #50: '5p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 5P LOSS MUTATED | 14 | 22 | 14 |
| 5P LOSS WILD-TYPE | 189 | 168 | 253 |
Figure S330. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S331. Gene #51: '5q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 5Q LOSS MUTATED | 6 | 20 | 5 | 11 |
| 5Q LOSS WILD-TYPE | 141 | 76 | 147 | 102 |
Figure S331. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S332. Gene #51: '5q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 5Q LOSS MUTATED | 9 | 22 | 4 | 7 |
| 5Q LOSS WILD-TYPE | 139 | 80 | 96 | 151 |
Figure S332. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00054 (Fisher's exact test), Q value = 0.0023
Table S333. Gene #51: '5q loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 5Q LOSS MUTATED | 4 | 26 | 6 | 6 |
| 5Q LOSS WILD-TYPE | 152 | 157 | 81 | 114 |
Figure S333. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 7e-04 (Fisher's exact test), Q value = 0.0029
Table S334. Gene #51: '5q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 5Q LOSS MUTATED | 25 | 49 | 4 |
| 5Q LOSS WILD-TYPE | 508 | 493 | 11 |
Figure S334. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 0.001
Table S335. Gene #51: '5q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 5Q LOSS MUTATED | 12 | 27 | 2 | 2 |
| 5Q LOSS WILD-TYPE | 172 | 210 | 62 | 163 |
Figure S335. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0369 (Fisher's exact test), Q value = 0.083
Table S336. Gene #51: '5q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 5Q LOSS MUTATED | 16 | 9 | 24 |
| 5Q LOSS WILD-TYPE | 208 | 195 | 194 |
Figure S336. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00541 (Fisher's exact test), Q value = 0.017
Table S337. Gene #51: '5q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 5Q LOSS MUTATED | 15 | 23 | 11 |
| 5Q LOSS WILD-TYPE | 188 | 167 | 256 |
Figure S337. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00041 (Fisher's exact test), Q value = 0.0018
Table S338. Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 5Q LOSS MUTATED | 6 | 17 | 9 | 1 |
| 5Q LOSS WILD-TYPE | 131 | 90 | 174 | 81 |
Figure S338. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S339. Gene #52: '6p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 6P LOSS MUTATED | 83 | 31 | 2 |
| 6P LOSS WILD-TYPE | 450 | 511 | 13 |
Figure S339. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S340. Gene #52: '6p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 6P LOSS MUTATED | 21 | 11 | 12 | 6 |
| 6P LOSS WILD-TYPE | 163 | 226 | 52 | 159 |
Figure S340. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0152 (Fisher's exact test), Q value = 0.041
Table S341. Gene #52: '6p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 6P LOSS MUTATED | 33 | 19 | 10 |
| 6P LOSS WILD-TYPE | 201 | 235 | 148 |
Figure S341. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S342. Gene #52: '6p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 6P LOSS MUTATED | 41 | 11 | 11 |
| 6P LOSS WILD-TYPE | 192 | 224 | 181 |
Figure S342. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S343. Gene #52: '6p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 6P LOSS MUTATED | 38 | 12 | 13 |
| 6P LOSS WILD-TYPE | 165 | 178 | 254 |
Figure S343. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00397 (Fisher's exact test), Q value = 0.013
Table S344. Gene #52: '6p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 6P LOSS MUTATED | 19 | 3 | 8 |
| 6P LOSS WILD-TYPE | 166 | 158 | 151 |
Figure S344. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.00137 (Fisher's exact test), Q value = 0.0052
Table S345. Gene #52: '6p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 6P LOSS MUTATED | 7 | 4 | 6 | 13 |
| 6P LOSS WILD-TYPE | 84 | 133 | 182 | 76 |
Figure S345. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S346. Gene #53: '6q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 6Q LOSS MUTATED | 121 | 66 | 2 |
| 6Q LOSS WILD-TYPE | 412 | 476 | 13 |
Figure S346. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S347. Gene #53: '6q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 6Q LOSS MUTATED | 35 | 37 | 14 | 8 |
| 6Q LOSS WILD-TYPE | 149 | 200 | 50 | 157 |
Figure S347. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0269 (Fisher's exact test), Q value = 0.065
Table S348. Gene #53: '6q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 6Q LOSS MUTATED | 42 | 21 | 39 |
| 6Q LOSS WILD-TYPE | 182 | 183 | 179 |
Figure S348. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00162 (Fisher's exact test), Q value = 0.0059
Table S349. Gene #53: '6q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 6Q LOSS MUTATED | 51 | 37 | 14 |
| 6Q LOSS WILD-TYPE | 183 | 217 | 144 |
Figure S349. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S350. Gene #53: '6q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 6Q LOSS MUTATED | 57 | 31 | 18 |
| 6Q LOSS WILD-TYPE | 176 | 204 | 174 |
Figure S350. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S351. Gene #53: '6q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 6Q LOSS MUTATED | 52 | 31 | 23 |
| 6Q LOSS WILD-TYPE | 151 | 159 | 244 |
Figure S351. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00059 (Fisher's exact test), Q value = 0.0025
Table S352. Gene #53: '6q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 6Q LOSS MUTATED | 30 | 14 | 16 | 4 |
| 6Q LOSS WILD-TYPE | 107 | 93 | 167 | 78 |
Figure S352. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.0184 (Fisher's exact test), Q value = 0.047
Table S353. Gene #53: '6q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 6Q LOSS MUTATED | 33 | 15 | 14 |
| 6Q LOSS WILD-TYPE | 152 | 146 | 145 |
Figure S353. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00054
Table S354. Gene #53: '6q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 6Q LOSS MUTATED | 21 | 8 | 15 | 18 |
| 6Q LOSS WILD-TYPE | 70 | 129 | 173 | 71 |
Figure S354. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0302 (Fisher's exact test), Q value = 0.071
Table S355. Gene #54: '7p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 7P LOSS MUTATED | 0 | 4 | 1 | 2 |
| 7P LOSS WILD-TYPE | 147 | 92 | 151 | 111 |
Figure S355. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0378 (Fisher's exact test), Q value = 0.084
Table S356. Gene #55: '7q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 7Q LOSS MUTATED | 4 | 0 | 0 |
| 7Q LOSS WILD-TYPE | 220 | 204 | 218 |
Figure S356. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00035
Table S357. Gene #56: '8p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 8P LOSS MUTATED | 55 | 19 | 0 |
| 8P LOSS WILD-TYPE | 478 | 523 | 15 |
Figure S357. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S358. Gene #56: '8p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 8P LOSS MUTATED | 21 | 6 | 1 | 0 |
| 8P LOSS WILD-TYPE | 163 | 231 | 63 | 165 |
Figure S358. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S359. Gene #56: '8p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 8P LOSS MUTATED | 25 | 2 | 4 |
| 8P LOSS WILD-TYPE | 208 | 233 | 188 |
Figure S359. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S360. Gene #56: '8p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 8P LOSS MUTATED | 22 | 6 | 3 |
| 8P LOSS WILD-TYPE | 181 | 184 | 264 |
Figure S360. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0338 (Fisher's exact test), Q value = 0.077
Table S361. Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 8P LOSS MUTATED | 8 | 5 | 3 | 0 |
| 8P LOSS WILD-TYPE | 129 | 102 | 180 | 82 |
Figure S361. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00104 (Fisher's exact test), Q value = 0.004
Table S362. Gene #56: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 8P LOSS MUTATED | 6 | 1 | 9 |
| 8P LOSS WILD-TYPE | 216 | 183 | 94 |
Figure S362. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00035 (Fisher's exact test), Q value = 0.0016
Table S363. Gene #56: '8p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 8P LOSS MUTATED | 1 | 4 | 1 | 9 |
| 8P LOSS WILD-TYPE | 90 | 133 | 187 | 80 |
Figure S363. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0382 (Fisher's exact test), Q value = 0.085
Table S364. Gene #57: '8q loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 8Q LOSS MUTATED | 20 | 9 | 6 | 6 |
| 8Q LOSS WILD-TYPE | 136 | 174 | 81 | 114 |
Figure S364. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S365. Gene #57: '8q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 8Q LOSS MUTATED | 45 | 7 | 0 |
| 8Q LOSS WILD-TYPE | 488 | 535 | 15 |
Figure S365. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S366. Gene #57: '8q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 8Q LOSS MUTATED | 17 | 2 | 1 | 0 |
| 8Q LOSS WILD-TYPE | 167 | 235 | 63 | 165 |
Figure S366. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S367. Gene #57: '8q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 8Q LOSS MUTATED | 19 | 1 | 3 |
| 8Q LOSS WILD-TYPE | 214 | 234 | 189 |
Figure S367. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S368. Gene #57: '8q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 8Q LOSS MUTATED | 18 | 3 | 2 |
| 8Q LOSS WILD-TYPE | 185 | 187 | 265 |
Figure S368. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00058 (Fisher's exact test), Q value = 0.0025
Table S369. Gene #57: '8q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 8Q LOSS MUTATED | 4 | 0 | 7 |
| 8Q LOSS WILD-TYPE | 218 | 184 | 96 |
Figure S369. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 7e-05 (Fisher's exact test), Q value = 4e-04
Table S370. Gene #57: '8q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 8Q LOSS MUTATED | 0 | 3 | 0 | 7 |
| 8Q LOSS WILD-TYPE | 91 | 134 | 188 | 82 |
Figure S370. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00346 (Fisher's exact test), Q value = 0.012
Table S371. Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 9P LOSS MUTATED | 50 | 19 | 63 | 43 |
| 9P LOSS WILD-TYPE | 97 | 77 | 89 | 70 |
Figure S371. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00035
Table S372. Gene #58: '9p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 9P LOSS MUTATED | 190 | 125 | 4 |
| 9P LOSS WILD-TYPE | 343 | 417 | 11 |
Figure S372. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S373. Gene #58: '9p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 9P LOSS MUTATED | 68 | 67 | 11 | 23 |
| 9P LOSS WILD-TYPE | 116 | 170 | 53 | 142 |
Figure S373. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00205 (Fisher's exact test), Q value = 0.0074
Table S374. Gene #58: '9p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 9P LOSS MUTATED | 59 | 45 | 81 |
| 9P LOSS WILD-TYPE | 165 | 159 | 137 |
Figure S374. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00542 (Fisher's exact test), Q value = 0.017
Table S375. Gene #58: '9p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 9P LOSS MUTATED | 78 | 77 | 30 |
| 9P LOSS WILD-TYPE | 156 | 177 | 128 |
Figure S375. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.00659 (Fisher's exact test), Q value = 0.02
Table S376. Gene #58: '9p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 9P LOSS MUTATED | 76 | 49 | 42 |
| 9P LOSS WILD-TYPE | 157 | 186 | 150 |
Figure S376. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.0106 (Fisher's exact test), Q value = 0.03
Table S377. Gene #58: '9p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 9P LOSS MUTATED | 65 | 49 | 53 |
| 9P LOSS WILD-TYPE | 138 | 141 | 214 |
Figure S377. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0334 (Fisher's exact test), Q value = 0.076
Table S378. Gene #58: '9p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 9P LOSS MUTATED | 22 | 23 | 42 | 30 |
| 9P LOSS WILD-TYPE | 69 | 114 | 146 | 59 |
Figure S378. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0329 (Fisher's exact test), Q value = 0.076
Table S379. Gene #59: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 9Q LOSS MUTATED | 20 | 8 | 21 | 29 |
| 9Q LOSS WILD-TYPE | 128 | 94 | 79 | 129 |
Figure S379. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0252 (Fisher's exact test), Q value = 0.062
Table S380. Gene #59: '9q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 9Q LOSS MUTATED | 85 | 57 | 1 |
| 9Q LOSS WILD-TYPE | 448 | 485 | 14 |
Figure S380. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.048 (Fisher's exact test), Q value = 0.1
Table S381. Gene #59: '9q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 9Q LOSS MUTATED | 30 | 40 | 12 |
| 9Q LOSS WILD-TYPE | 204 | 214 | 146 |
Figure S381. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.00578 (Fisher's exact test), Q value = 0.018
Table S382. Gene #59: '9q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 9Q LOSS MUTATED | 41 | 20 | 18 |
| 9Q LOSS WILD-TYPE | 192 | 215 | 174 |
Figure S382. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.0245 (Fisher's exact test), Q value = 0.06
Table S383. Gene #59: '9q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 9Q LOSS MUTATED | 35 | 19 | 25 |
| 9Q LOSS WILD-TYPE | 168 | 171 | 242 |
Figure S383. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0204 (Fisher's exact test), Q value = 0.052
Table S384. Gene #59: '9q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 9Q LOSS MUTATED | 10 | 7 | 18 | 16 |
| 9Q LOSS WILD-TYPE | 81 | 130 | 170 | 73 |
Figure S384. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S385. Gene #60: '10p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 10P LOSS MUTATED | 132 | 64 | 140 | 83 |
| 10P LOSS WILD-TYPE | 15 | 32 | 12 | 30 |
Figure S385. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S386. Gene #60: '10p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 10P LOSS MUTATED | 127 | 62 | 93 | 137 |
| 10P LOSS WILD-TYPE | 21 | 40 | 7 | 21 |
Figure S386. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0127 (Fisher's exact test), Q value = 0.035
Table S387. Gene #60: '10p loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 10P LOSS MUTATED | 141 | 145 | 67 | 101 |
| 10P LOSS WILD-TYPE | 15 | 38 | 20 | 19 |
Figure S387. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.00063
Table S388. Gene #60: '10p loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 10P LOSS MUTATED | 226 | 108 | 120 |
| 10P LOSS WILD-TYPE | 67 | 16 | 9 |
Figure S388. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S389. Gene #60: '10p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 10P LOSS MUTATED | 497 | 53 | 13 |
| 10P LOSS WILD-TYPE | 36 | 489 | 2 |
Figure S389. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S390. Gene #60: '10p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 10P LOSS MUTATED | 171 | 7 | 21 | 7 |
| 10P LOSS WILD-TYPE | 13 | 230 | 43 | 158 |
Figure S390. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.00087
Table S391. Gene #60: '10p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 10P LOSS MUTATED | 95 | 56 | 101 |
| 10P LOSS WILD-TYPE | 129 | 148 | 117 |
Figure S391. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00054
Table S392. Gene #60: '10p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 10P LOSS MUTATED | 101 | 112 | 39 |
| 10P LOSS WILD-TYPE | 133 | 142 | 119 |
Figure S392. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S393. Gene #60: '10p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 10P LOSS MUTATED | 187 | 5 | 22 |
| 10P LOSS WILD-TYPE | 46 | 230 | 170 |
Figure S393. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S394. Gene #60: '10p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 10P LOSS MUTATED | 181 | 10 | 23 |
| 10P LOSS WILD-TYPE | 22 | 180 | 244 |
Figure S394. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S395. Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 10P LOSS MUTATED | 33 | 26 | 20 | 4 |
| 10P LOSS WILD-TYPE | 104 | 81 | 163 | 78 |
Figure S395. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S396. Gene #60: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 10P LOSS MUTATED | 11 | 12 | 60 |
| 10P LOSS WILD-TYPE | 211 | 172 | 43 |
Figure S396. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S397. Gene #60: '10p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 10P LOSS MUTATED | 62 | 3 | 18 |
| 10P LOSS WILD-TYPE | 123 | 158 | 141 |
Figure S397. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S398. Gene #60: '10p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 10P LOSS MUTATED | 4 | 5 | 11 | 63 |
| 10P LOSS WILD-TYPE | 87 | 132 | 177 | 26 |
Figure S398. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S399. Gene #61: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 10Q LOSS MUTATED | 133 | 68 | 145 | 87 |
| 10Q LOSS WILD-TYPE | 14 | 28 | 7 | 26 |
Figure S399. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S400. Gene #61: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 10Q LOSS MUTATED | 128 | 69 | 97 | 139 |
| 10Q LOSS WILD-TYPE | 20 | 33 | 3 | 19 |
Figure S400. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00307 (Fisher's exact test), Q value = 0.011
Table S401. Gene #61: '10q loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 10Q LOSS MUTATED | 145 | 152 | 67 | 104 |
| 10Q LOSS WILD-TYPE | 11 | 31 | 20 | 16 |
Figure S401. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S402. Gene #61: '10q loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 10Q LOSS MUTATED | 236 | 109 | 123 |
| 10Q LOSS WILD-TYPE | 57 | 15 | 6 |
Figure S402. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S403. Gene #61: '10q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 10Q LOSS MUTATED | 501 | 75 | 15 |
| 10Q LOSS WILD-TYPE | 32 | 467 | 0 |
Figure S403. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S404. Gene #61: '10q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 10Q LOSS MUTATED | 171 | 21 | 21 | 7 |
| 10Q LOSS WILD-TYPE | 13 | 216 | 43 | 158 |
Figure S404. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S405. Gene #61: '10q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 10Q LOSS MUTATED | 100 | 58 | 109 |
| 10Q LOSS WILD-TYPE | 124 | 146 | 109 |
Figure S405. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 4e-04
Table S406. Gene #61: '10q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 10Q LOSS MUTATED | 108 | 117 | 42 |
| 10Q LOSS WILD-TYPE | 126 | 137 | 116 |
Figure S406. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S407. Gene #61: '10q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 10Q LOSS MUTATED | 193 | 13 | 24 |
| 10Q LOSS WILD-TYPE | 40 | 222 | 168 |
Figure S407. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S408. Gene #61: '10q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 10Q LOSS MUTATED | 184 | 21 | 25 |
| 10Q LOSS WILD-TYPE | 19 | 169 | 242 |
Figure S408. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S409. Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 10Q LOSS MUTATED | 36 | 32 | 24 | 5 |
| 10Q LOSS WILD-TYPE | 101 | 75 | 159 | 77 |
Figure S409. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S410. Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 10Q LOSS MUTATED | 15 | 15 | 67 |
| 10Q LOSS WILD-TYPE | 207 | 169 | 36 |
Figure S410. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S411. Gene #61: '10q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 10Q LOSS MUTATED | 68 | 7 | 22 |
| 10Q LOSS WILD-TYPE | 117 | 154 | 137 |
Figure S411. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S412. Gene #61: '10q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 10Q LOSS MUTATED | 7 | 7 | 16 | 67 |
| 10Q LOSS WILD-TYPE | 84 | 130 | 172 | 22 |
Figure S412. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S413. Gene #62: '11p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 11P LOSS MUTATED | 27 | 32 | 9 | 22 |
| 11P LOSS WILD-TYPE | 120 | 64 | 143 | 91 |
Figure S413. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S414. Gene #62: '11p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 11P LOSS MUTATED | 26 | 36 | 4 | 24 |
| 11P LOSS WILD-TYPE | 122 | 66 | 96 | 134 |
Figure S414. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0136 (Fisher's exact test), Q value = 0.037
Table S415. Gene #62: '11p loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 11P LOSS MUTATED | 63 | 20 | 13 |
| 11P LOSS WILD-TYPE | 230 | 104 | 116 |
Figure S415. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 0.00095 (Fisher's exact test), Q value = 0.0038
Table S416. Gene #62: '11p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 11P LOSS MUTATED | 80 | 75 | 8 |
| 11P LOSS WILD-TYPE | 453 | 467 | 7 |
Figure S416. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S417. Gene #62: '11p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 11P LOSS MUTATED | 20 | 52 | 5 | 0 |
| 11P LOSS WILD-TYPE | 164 | 185 | 59 | 165 |
Figure S417. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0218 (Fisher's exact test), Q value = 0.055
Table S418. Gene #62: '11p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 11P LOSS MUTATED | 22 | 21 | 39 |
| 11P LOSS WILD-TYPE | 202 | 183 | 179 |
Figure S418. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00079
Table S419. Gene #62: '11p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 11P LOSS MUTATED | 49 | 25 | 16 |
| 11P LOSS WILD-TYPE | 184 | 210 | 176 |
Figure S419. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S420. Gene #62: '11p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 11P LOSS MUTATED | 33 | 43 | 14 |
| 11P LOSS WILD-TYPE | 170 | 147 | 253 |
Figure S420. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S421. Gene #62: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 11P LOSS MUTATED | 14 | 29 | 17 | 4 |
| 11P LOSS WILD-TYPE | 123 | 78 | 166 | 78 |
Figure S421. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 4e-04
Table S422. Gene #62: '11p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11P LOSS MUTATED | 23 | 14 | 27 |
| 11P LOSS WILD-TYPE | 199 | 170 | 76 |
Figure S422. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0177 (Fisher's exact test), Q value = 0.046
Table S423. Gene #62: '11p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 11P LOSS MUTATED | 11 | 16 | 16 | 20 |
| 11P LOSS WILD-TYPE | 80 | 121 | 172 | 69 |
Figure S423. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00019
Table S424. Gene #63: '11q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 11Q LOSS MUTATED | 31 | 28 | 10 | 16 |
| 11Q LOSS WILD-TYPE | 116 | 68 | 142 | 97 |
Figure S424. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0015
Table S425. Gene #63: '11q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 11Q LOSS MUTATED | 28 | 27 | 5 | 25 |
| 11Q LOSS WILD-TYPE | 120 | 75 | 95 | 133 |
Figure S425. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S426. Gene #63: '11q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 11Q LOSS MUTATED | 84 | 22 | 7 |
| 11Q LOSS WILD-TYPE | 449 | 520 | 8 |
Figure S426. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00035
Table S427. Gene #63: '11q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 11Q LOSS MUTATED | 18 | 11 | 4 | 0 |
| 11Q LOSS WILD-TYPE | 166 | 226 | 60 | 165 |
Figure S427. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S428. Gene #63: '11q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 11Q LOSS MUTATED | 39 | 3 | 4 |
| 11Q LOSS WILD-TYPE | 194 | 232 | 188 |
Figure S428. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S429. Gene #63: '11q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 11Q LOSS MUTATED | 32 | 10 | 4 |
| 11Q LOSS WILD-TYPE | 171 | 180 | 263 |
Figure S429. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0243 (Fisher's exact test), Q value = 0.06
Table S430. Gene #63: '11q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 11Q LOSS MUTATED | 7 | 9 | 6 | 0 |
| 11Q LOSS WILD-TYPE | 130 | 98 | 177 | 82 |
Figure S430. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.00083
Table S431. Gene #63: '11q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 11Q LOSS MUTATED | 6 | 3 | 13 |
| 11Q LOSS WILD-TYPE | 216 | 181 | 90 |
Figure S431. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00107 (Fisher's exact test), Q value = 0.0041
Table S432. Gene #63: '11q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 11Q LOSS MUTATED | 2 | 5 | 3 | 11 |
| 11Q LOSS WILD-TYPE | 89 | 132 | 185 | 78 |
Figure S432. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0273 (Fisher's exact test), Q value = 0.066
Table S433. Gene #64: '12p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 12P LOSS MUTATED | 45 | 37 | 4 |
| 12P LOSS WILD-TYPE | 488 | 505 | 11 |
Figure S433. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0489 (Fisher's exact test), Q value = 0.1
Table S434. Gene #64: '12p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 12P LOSS MUTATED | 8 | 22 | 3 | 5 |
| 12P LOSS WILD-TYPE | 176 | 215 | 61 | 160 |
Figure S434. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0182 (Fisher's exact test), Q value = 0.047
Table S435. Gene #64: '12p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 12P LOSS MUTATED | 15 | 18 | 9 |
| 12P LOSS WILD-TYPE | 188 | 172 | 258 |
Figure S435. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00542 (Fisher's exact test), Q value = 0.017
Table S436. Gene #65: '12q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 12Q LOSS MUTATED | 43 | 61 | 5 |
| 12Q LOSS WILD-TYPE | 490 | 481 | 10 |
Figure S436. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S437. Gene #65: '12q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 12Q LOSS MUTATED | 7 | 46 | 5 | 5 |
| 12Q LOSS WILD-TYPE | 177 | 191 | 59 | 160 |
Figure S437. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00035
Table S438. Gene #65: '12q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 12Q LOSS MUTATED | 15 | 36 | 16 |
| 12Q LOSS WILD-TYPE | 188 | 154 | 251 |
Figure S438. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00947 (Fisher's exact test), Q value = 0.028
Table S439. Gene #65: '12q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 12Q LOSS MUTATED | 9 | 21 | 17 | 6 |
| 12Q LOSS WILD-TYPE | 128 | 86 | 166 | 76 |
Figure S439. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00025
Table S440. Gene #66: '13q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 13Q LOSS MUTATED | 57 | 35 | 26 | 45 |
| 13Q LOSS WILD-TYPE | 90 | 61 | 126 | 68 |
Figure S440. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0015 (Fisher's exact test), Q value = 0.0056
Table S441. Gene #66: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 13Q LOSS MUTATED | 50 | 41 | 17 | 55 |
| 13Q LOSS WILD-TYPE | 98 | 61 | 83 | 103 |
Figure S441. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00049
Table S442. Gene #66: '13q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 13Q LOSS MUTATED | 168 | 121 | 9 |
| 13Q LOSS WILD-TYPE | 365 | 421 | 6 |
Figure S442. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0169 (Fisher's exact test), Q value = 0.045
Table S443. Gene #66: '13q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 13Q LOSS MUTATED | 53 | 59 | 11 | 26 |
| 13Q LOSS WILD-TYPE | 131 | 178 | 53 | 139 |
Figure S443. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0022
Table S444. Gene #66: '13q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 13Q LOSS MUTATED | 74 | 54 | 30 |
| 13Q LOSS WILD-TYPE | 159 | 181 | 162 |
Figure S444. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00036 (Fisher's exact test), Q value = 0.0016
Table S445. Gene #66: '13q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 13Q LOSS MUTATED | 59 | 56 | 43 |
| 13Q LOSS WILD-TYPE | 144 | 134 | 224 |
Figure S445. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00921 (Fisher's exact test), Q value = 0.027
Table S446. Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 13Q LOSS MUTATED | 52 | 28 | 31 |
| 13Q LOSS WILD-TYPE | 170 | 156 | 72 |
Figure S446. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S447. Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 14Q LOSS MUTATED | 46 | 33 | 17 | 39 |
| 14Q LOSS WILD-TYPE | 101 | 63 | 135 | 74 |
Figure S447. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00054
Table S448. Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 14Q LOSS MUTATED | 43 | 35 | 10 | 47 |
| 14Q LOSS WILD-TYPE | 105 | 67 | 90 | 111 |
Figure S448. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S449. Gene #67: '14q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 14Q LOSS MUTATED | 137 | 80 | 8 |
| 14Q LOSS WILD-TYPE | 396 | 462 | 7 |
Figure S449. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00071
Table S450. Gene #67: '14q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 14Q LOSS MUTATED | 51 | 30 | 15 | 20 |
| 14Q LOSS WILD-TYPE | 133 | 207 | 49 | 145 |
Figure S450. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S451. Gene #67: '14q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 14Q LOSS MUTATED | 75 | 26 | 28 |
| 14Q LOSS WILD-TYPE | 158 | 209 | 164 |
Figure S451. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S452. Gene #67: '14q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 14Q LOSS MUTATED | 66 | 29 | 34 |
| 14Q LOSS WILD-TYPE | 137 | 161 | 233 |
Figure S452. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00333 (Fisher's exact test), Q value = 0.011
Table S453. Gene #67: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 14Q LOSS MUTATED | 35 | 12 | 22 | 9 |
| 14Q LOSS WILD-TYPE | 102 | 95 | 161 | 73 |
Figure S453. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.00219 (Fisher's exact test), Q value = 0.0079
Table S454. Gene #67: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 14Q LOSS MUTATED | 28 | 22 | 28 |
| 14Q LOSS WILD-TYPE | 194 | 162 | 75 |
Figure S454. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00728 (Fisher's exact test), Q value = 0.022
Table S455. Gene #67: '14q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 14Q LOSS MUTATED | 41 | 18 | 19 |
| 14Q LOSS WILD-TYPE | 144 | 143 | 140 |
Figure S455. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.00058 (Fisher's exact test), Q value = 0.0025
Table S456. Gene #67: '14q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 14Q LOSS MUTATED | 14 | 15 | 22 | 27 |
| 14Q LOSS WILD-TYPE | 77 | 122 | 166 | 62 |
Figure S456. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00025
Table S457. Gene #68: '15q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 15Q LOSS MUTATED | 26 | 26 | 12 | 31 |
| 15Q LOSS WILD-TYPE | 121 | 70 | 140 | 82 |
Figure S457. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S458. Gene #68: '15q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 15Q LOSS MUTATED | 22 | 37 | 7 | 29 |
| 15Q LOSS WILD-TYPE | 126 | 65 | 93 | 129 |
Figure S458. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0038 (Fisher's exact test), Q value = 0.013
Table S459. Gene #68: '15q loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 15Q LOSS MUTATED | 21 | 48 | 15 | 14 |
| 15Q LOSS WILD-TYPE | 135 | 135 | 72 | 106 |
Figure S459. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00366 (Fisher's exact test), Q value = 0.012
Table S460. Gene #68: '15q loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 15Q LOSS MUTATED | 65 | 11 | 22 |
| 15Q LOSS WILD-TYPE | 228 | 113 | 107 |
Figure S460. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 0.0443 (Fisher's exact test), Q value = 0.095
Table S461. Gene #68: '15q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 15Q LOSS MUTATED | 89 | 64 | 3 |
| 15Q LOSS WILD-TYPE | 444 | 478 | 12 |
Figure S461. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00121 (Fisher's exact test), Q value = 0.0046
Table S462. Gene #68: '15q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 15Q LOSS MUTATED | 23 | 19 | 1 | 28 |
| 15Q LOSS WILD-TYPE | 161 | 218 | 63 | 137 |
Figure S462. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S463. Gene #69: '16p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 16P LOSS MUTATED | 56 | 19 | 3 |
| 16P LOSS WILD-TYPE | 477 | 523 | 12 |
Figure S463. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00406 (Fisher's exact test), Q value = 0.013
Table S464. Gene #69: '16p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 16P LOSS MUTATED | 17 | 9 | 2 | 2 |
| 16P LOSS WILD-TYPE | 167 | 228 | 62 | 163 |
Figure S464. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0073 (Fisher's exact test), Q value = 0.022
Table S465. Gene #69: '16p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 16P LOSS MUTATED | 19 | 14 | 2 |
| 16P LOSS WILD-TYPE | 215 | 240 | 156 |
Figure S465. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.00018 (Fisher's exact test), Q value = 0.00087
Table S466. Gene #69: '16p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 16P LOSS MUTATED | 26 | 6 | 6 |
| 16P LOSS WILD-TYPE | 207 | 229 | 186 |
Figure S466. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00045 (Fisher's exact test), Q value = 0.002
Table S467. Gene #69: '16p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 16P LOSS MUTATED | 23 | 5 | 10 |
| 16P LOSS WILD-TYPE | 180 | 185 | 257 |
Figure S467. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S468. Gene #70: '16q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 16Q LOSS MUTATED | 77 | 24 | 4 |
| 16Q LOSS WILD-TYPE | 456 | 518 | 11 |
Figure S468. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S469. Gene #70: '16q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 16Q LOSS MUTATED | 29 | 11 | 3 | 3 |
| 16Q LOSS WILD-TYPE | 155 | 226 | 61 | 162 |
Figure S469. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00822 (Fisher's exact test), Q value = 0.024
Table S470. Gene #70: '16q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 16Q LOSS MUTATED | 22 | 7 | 23 |
| 16Q LOSS WILD-TYPE | 202 | 197 | 195 |
Figure S470. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 3e-04
Table S471. Gene #70: '16q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 16Q LOSS MUTATED | 32 | 17 | 3 |
| 16Q LOSS WILD-TYPE | 202 | 237 | 155 |
Figure S471. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S472. Gene #70: '16q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 16Q LOSS MUTATED | 35 | 8 | 7 |
| 16Q LOSS WILD-TYPE | 198 | 227 | 185 |
Figure S472. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S473. Gene #70: '16q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 16Q LOSS MUTATED | 32 | 7 | 11 |
| 16Q LOSS WILD-TYPE | 171 | 183 | 256 |
Figure S473. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00353 (Fisher's exact test), Q value = 0.012
Table S474. Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 16Q LOSS MUTATED | 7 | 4 | 11 |
| 16Q LOSS WILD-TYPE | 215 | 180 | 92 |
Figure S474. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00906 (Fisher's exact test), Q value = 0.027
Table S475. Gene #70: '16q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 16Q LOSS MUTATED | 3 | 4 | 4 | 10 |
| 16Q LOSS WILD-TYPE | 88 | 133 | 184 | 79 |
Figure S475. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0229 (Fisher's exact test), Q value = 0.057
Table S476. Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 17P LOSS MUTATED | 25 | 12 | 10 | 9 |
| 17P LOSS WILD-TYPE | 122 | 84 | 142 | 104 |
Figure S476. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0278 (Fisher's exact test), Q value = 0.066
Table S477. Gene #71: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 17P LOSS MUTATED | 23 | 15 | 8 | 10 |
| 17P LOSS WILD-TYPE | 125 | 87 | 92 | 148 |
Figure S477. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S478. Gene #71: '17p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 17P LOSS MUTATED | 54 | 19 | 4 |
| 17P LOSS WILD-TYPE | 479 | 523 | 11 |
Figure S478. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00064 (Fisher's exact test), Q value = 0.0027
Table S479. Gene #71: '17p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 17P LOSS MUTATED | 18 | 6 | 3 | 2 |
| 17P LOSS WILD-TYPE | 166 | 231 | 61 | 163 |
Figure S479. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S480. Gene #71: '17p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 17P LOSS MUTATED | 27 | 4 | 3 |
| 17P LOSS WILD-TYPE | 206 | 231 | 189 |
Figure S480. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S481. Gene #71: '17p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 17P LOSS MUTATED | 23 | 7 | 4 |
| 17P LOSS WILD-TYPE | 180 | 183 | 263 |
Figure S481. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00639 (Fisher's exact test), Q value = 0.02
Table S482. Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 17P LOSS MUTATED | 5 | 1 | 7 |
| 17P LOSS WILD-TYPE | 217 | 183 | 96 |
Figure S482. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0119 (Fisher's exact test), Q value = 0.033
Table S483. Gene #71: '17p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 17P LOSS MUTATED | 3 | 2 | 1 | 6 |
| 17P LOSS WILD-TYPE | 88 | 135 | 187 | 83 |
Figure S483. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00527 (Fisher's exact test), Q value = 0.017
Table S484. Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 17Q LOSS MUTATED | 19 | 7 | 9 | 2 |
| 17Q LOSS WILD-TYPE | 128 | 89 | 143 | 111 |
Figure S484. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.044 (Fisher's exact test), Q value = 0.095
Table S485. Gene #72: '17q loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 293 | 124 | 129 |
| 17Q LOSS MUTATED | 15 | 15 | 11 |
| 17Q LOSS WILD-TYPE | 278 | 109 | 118 |
Figure S485. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'
P value = 0.00024 (Fisher's exact test), Q value = 0.0011
Table S486. Gene #72: '17q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 17Q LOSS MUTATED | 37 | 12 | 2 |
| 17Q LOSS WILD-TYPE | 496 | 530 | 13 |
Figure S486. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00276 (Fisher's exact test), Q value = 0.0097
Table S487. Gene #72: '17q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 17Q LOSS MUTATED | 12 | 3 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 172 | 234 | 62 | 164 |
Figure S487. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.0175 (Fisher's exact test), Q value = 0.046
Table S488. Gene #72: '17q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 17Q LOSS MUTATED | 15 | 3 | 7 |
| 17Q LOSS WILD-TYPE | 209 | 201 | 211 |
Figure S488. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0156 (Fisher's exact test), Q value = 0.042
Table S489. Gene #72: '17q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 17Q LOSS MUTATED | 14 | 10 | 1 |
| 17Q LOSS WILD-TYPE | 220 | 244 | 157 |
Figure S489. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.00149 (Fisher's exact test), Q value = 0.0056
Table S490. Gene #72: '17q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 17Q LOSS MUTATED | 15 | 3 | 2 |
| 17Q LOSS WILD-TYPE | 218 | 232 | 190 |
Figure S490. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00062 (Fisher's exact test), Q value = 0.0026
Table S491. Gene #72: '17q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 17Q LOSS MUTATED | 14 | 4 | 2 |
| 17Q LOSS WILD-TYPE | 189 | 186 | 265 |
Figure S491. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0226 (Fisher's exact test), Q value = 0.057
Table S492. Gene #72: '17q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 17Q LOSS MUTATED | 3 | 0 | 1 | 3 |
| 17Q LOSS WILD-TYPE | 88 | 137 | 187 | 86 |
Figure S492. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0477 (Fisher's exact test), Q value = 0.1
Table S493. Gene #73: '18p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 18P LOSS MUTATED | 20 | 15 | 9 | 15 |
| 18P LOSS WILD-TYPE | 127 | 81 | 143 | 98 |
Figure S493. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0336 (Fisher's exact test), Q value = 0.077
Table S494. Gene #73: '18p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 18P LOSS MUTATED | 19 | 16 | 4 | 20 |
| 18P LOSS WILD-TYPE | 129 | 86 | 96 | 138 |
Figure S494. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0259 (Fisher's exact test), Q value = 0.063
Table S495. Gene #73: '18p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 18P LOSS MUTATED | 29 | 22 | 6 | 31 |
| 18P LOSS WILD-TYPE | 155 | 215 | 58 | 134 |
Figure S495. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00866 (Fisher's exact test), Q value = 0.025
Table S496. Gene #74: '18q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 18Q LOSS MUTATED | 18 | 12 | 2 | 20 |
| 18Q LOSS WILD-TYPE | 130 | 90 | 98 | 138 |
Figure S496. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00101 (Fisher's exact test), Q value = 0.004
Table S497. Gene #74: '18q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 18Q LOSS MUTATED | 19 | 19 | 4 | 34 |
| 18Q LOSS WILD-TYPE | 165 | 218 | 60 | 131 |
Figure S497. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00099 (Fisher's exact test), Q value = 0.0039
Table S498. Gene #75: '19p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 19P LOSS MUTATED | 3 | 10 | 2 | 9 |
| 19P LOSS WILD-TYPE | 144 | 86 | 150 | 104 |
Figure S498. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00301 (Fisher's exact test), Q value = 0.01
Table S499. Gene #75: '19p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 19P LOSS MUTATED | 4 | 12 | 1 | 7 |
| 19P LOSS WILD-TYPE | 144 | 90 | 99 | 151 |
Figure S499. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00903 (Fisher's exact test), Q value = 0.027
Table S500. Gene #75: '19p loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 19P LOSS MUTATED | 17 | 39 | 1 |
| 19P LOSS WILD-TYPE | 516 | 503 | 14 |
Figure S500. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.00549 (Fisher's exact test), Q value = 0.017
Table S501. Gene #75: '19p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 19P LOSS MUTATED | 6 | 18 | 6 |
| 19P LOSS WILD-TYPE | 179 | 143 | 153 |
Figure S501. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.00699 (Fisher's exact test), Q value = 0.021
Table S502. Gene #76: '19q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 19Q LOSS MUTATED | 6 | 10 | 3 | 11 |
| 19Q LOSS WILD-TYPE | 141 | 86 | 149 | 102 |
Figure S502. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0113 (Fisher's exact test), Q value = 0.032
Table S503. Gene #76: '19q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 19Q LOSS MUTATED | 7 | 12 | 1 | 10 |
| 19Q LOSS WILD-TYPE | 141 | 90 | 99 | 148 |
Figure S503. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S504. Gene #76: '19q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 19Q LOSS MUTATED | 23 | 220 | 1 |
| 19Q LOSS WILD-TYPE | 510 | 322 | 14 |
Figure S504. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S505. Gene #76: '19q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 19Q LOSS MUTATED | 11 | 31 | 12 | 164 |
| 19Q LOSS WILD-TYPE | 173 | 206 | 52 | 1 |
Figure S505. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00853 (Fisher's exact test), Q value = 0.025
Table S506. Gene #76: '19q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 19Q LOSS MUTATED | 54 | 77 | 63 |
| 19Q LOSS WILD-TYPE | 170 | 127 | 155 |
Figure S506. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00079
Table S507. Gene #76: '19q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 19Q LOSS MUTATED | 60 | 65 | 69 |
| 19Q LOSS WILD-TYPE | 174 | 189 | 89 |
Figure S507. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S508. Gene #76: '19q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 19Q LOSS MUTATED | 19 | 98 | 104 |
| 19Q LOSS WILD-TYPE | 214 | 137 | 88 |
Figure S508. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S509. Gene #76: '19q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 19Q LOSS MUTATED | 12 | 30 | 179 |
| 19Q LOSS WILD-TYPE | 191 | 160 | 88 |
Figure S509. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S510. Gene #76: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| 19Q LOSS MUTATED | 31 | 23 | 88 | 68 |
| 19Q LOSS WILD-TYPE | 106 | 84 | 95 | 14 |
Figure S510. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S511. Gene #76: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 19Q LOSS MUTATED | 97 | 103 | 10 |
| 19Q LOSS WILD-TYPE | 125 | 81 | 93 |
Figure S511. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S512. Gene #76: '19q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 19Q LOSS MUTATED | 34 | 96 | 79 |
| 19Q LOSS WILD-TYPE | 151 | 65 | 80 |
Figure S512. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S513. Gene #76: '19q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 19Q LOSS MUTATED | 11 | 92 | 97 | 9 |
| 19Q LOSS WILD-TYPE | 80 | 45 | 91 | 80 |
Figure S513. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00067
Table S514. Gene #77: '20p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 20P LOSS MUTATED | 4 | 10 | 0 | 3 |
| 20P LOSS WILD-TYPE | 143 | 86 | 152 | 110 |
Figure S514. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00045
Table S515. Gene #77: '20p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 20P LOSS MUTATED | 5 | 11 | 0 | 1 |
| 20P LOSS WILD-TYPE | 143 | 91 | 100 | 157 |
Figure S515. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0363 (Fisher's exact test), Q value = 0.081
Table S516. Gene #77: '20p loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| 20P LOSS MUTATED | 2 | 7 | 7 | 2 |
| 20P LOSS WILD-TYPE | 154 | 176 | 80 | 118 |
Figure S516. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00134 (Fisher's exact test), Q value = 0.0051
Table S517. Gene #78: '20q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 20Q LOSS MUTATED | 4 | 8 | 0 | 3 |
| 20Q LOSS WILD-TYPE | 143 | 88 | 152 | 110 |
Figure S517. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 1e-04 (Fisher's exact test), Q value = 0.00054
Table S518. Gene #78: '20q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 20Q LOSS MUTATED | 4 | 10 | 0 | 1 |
| 20Q LOSS WILD-TYPE | 144 | 92 | 100 | 157 |
Figure S518. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00502 (Fisher's exact test), Q value = 0.016
Table S519. Gene #78: '20q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 20Q LOSS MUTATED | 14 | 5 | 2 |
| 20Q LOSS WILD-TYPE | 519 | 537 | 13 |
Figure S519. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 0.0125 (Fisher's exact test), Q value = 0.034
Table S520. Gene #78: '20q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 20Q LOSS MUTATED | 2 | 5 | 0 |
| 20Q LOSS WILD-TYPE | 201 | 185 | 267 |
Figure S520. Get High-res Image Gene #78: '20q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0215 (Fisher's exact test), Q value = 0.054
Table S521. Gene #79: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| 21Q LOSS MUTATED | 4 | 12 | 10 | 10 |
| 21Q LOSS WILD-TYPE | 143 | 84 | 142 | 103 |
Figure S521. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.00112 (Fisher's exact test), Q value = 0.0043
Table S522. Gene #79: '21q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| 21Q LOSS MUTATED | 5 | 17 | 6 | 8 |
| 21Q LOSS WILD-TYPE | 143 | 85 | 94 | 150 |
Figure S522. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00025
Table S523. Gene #79: '21q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 21Q LOSS MUTATED | 9 | 31 | 4 | 2 |
| 21Q LOSS WILD-TYPE | 175 | 206 | 60 | 163 |
Figure S523. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S524. Gene #79: '21q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 21Q LOSS MUTATED | 10 | 28 | 8 |
| 21Q LOSS WILD-TYPE | 193 | 162 | 259 |
Figure S524. Get High-res Image Gene #79: '21q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S525. Gene #80: '22q loss' versus Molecular Subtype #5: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 533 | 542 | 15 |
| 22Q LOSS MUTATED | 177 | 58 | 5 |
| 22Q LOSS WILD-TYPE | 356 | 484 | 10 |
Figure S525. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #5: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S526. Gene #80: '22q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| 22Q LOSS MUTATED | 58 | 27 | 13 | 5 |
| 22Q LOSS WILD-TYPE | 126 | 210 | 51 | 160 |
Figure S526. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 0.00326 (Fisher's exact test), Q value = 0.011
Table S527. Gene #80: '22q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| 22Q LOSS MUTATED | 37 | 28 | 57 |
| 22Q LOSS WILD-TYPE | 187 | 176 | 161 |
Figure S527. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0312 (Fisher's exact test), Q value = 0.072
Table S528. Gene #80: '22q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| 22Q LOSS MUTATED | 51 | 52 | 19 |
| 22Q LOSS WILD-TYPE | 183 | 202 | 139 |
Figure S528. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S529. Gene #80: '22q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| 22Q LOSS MUTATED | 73 | 20 | 18 |
| 22Q LOSS WILD-TYPE | 160 | 215 | 174 |
Figure S529. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 7.6e-05
Table S530. Gene #80: '22q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| 22Q LOSS MUTATED | 69 | 23 | 19 |
| 22Q LOSS WILD-TYPE | 134 | 167 | 248 |
Figure S530. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00026 (Fisher's exact test), Q value = 0.0012
Table S531. Gene #80: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 222 | 184 | 103 |
| 22Q LOSS MUTATED | 18 | 15 | 24 |
| 22Q LOSS WILD-TYPE | 204 | 169 | 79 |
Figure S531. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0111 (Fisher's exact test), Q value = 0.031
Table S532. Gene #80: '22q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| 22Q LOSS MUTATED | 31 | 13 | 12 |
| 22Q LOSS WILD-TYPE | 154 | 148 | 147 |
Figure S532. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 4e-04
Table S533. Gene #80: '22q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| 22Q LOSS MUTATED | 5 | 13 | 15 | 23 |
| 22Q LOSS WILD-TYPE | 86 | 124 | 173 | 66 |
Figure S533. Get High-res Image Gene #80: '22q loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00582 (Fisher's exact test), Q value = 0.018
Table S534. Gene #81: 'xp loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| XP LOSS MUTATED | 20 | 31 | 28 | 22 |
| XP LOSS WILD-TYPE | 127 | 65 | 124 | 91 |
Figure S534. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.008 (Fisher's exact test), Q value = 0.024
Table S535. Gene #81: 'xp loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| XP LOSS MUTATED | 20 | 32 | 19 | 30 |
| XP LOSS WILD-TYPE | 128 | 70 | 81 | 128 |
Figure S535. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.0304 (Fisher's exact test), Q value = 0.071
Table S536. Gene #81: 'xp loss' versus Molecular Subtype #3: 'MIR_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 156 | 183 | 87 | 120 |
| XP LOSS MUTATED | 24 | 48 | 17 | 17 |
| XP LOSS WILD-TYPE | 132 | 135 | 70 | 103 |
Figure S536. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #3: 'MIR_CNMF'
P value = 0.00097 (Fisher's exact test), Q value = 0.0039
Table S537. Gene #81: 'xp loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| XP LOSS MUTATED | 48 | 28 | 62 |
| XP LOSS WILD-TYPE | 176 | 176 | 156 |
Figure S537. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.0136 (Fisher's exact test), Q value = 0.037
Table S538. Gene #81: 'xp loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 234 | 254 | 158 |
| XP LOSS MUTATED | 61 | 55 | 22 |
| XP LOSS WILD-TYPE | 173 | 199 | 136 |
Figure S538. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'
P value = 0.01 (Fisher's exact test), Q value = 0.029
Table S539. Gene #81: 'xp loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| XP LOSS MUTATED | 60 | 52 | 27 |
| XP LOSS WILD-TYPE | 173 | 183 | 165 |
Figure S539. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.037
Table S540. Gene #81: 'xp loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 203 | 190 | 267 |
| XP LOSS MUTATED | 44 | 52 | 43 |
| XP LOSS WILD-TYPE | 159 | 138 | 224 |
Figure S540. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0379 (Fisher's exact test), Q value = 0.084
Table S541. Gene #81: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| XP LOSS MUTATED | 23 | 25 | 28 | 24 |
| XP LOSS WILD-TYPE | 114 | 82 | 155 | 58 |
Figure S541. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.0394 (Fisher's exact test), Q value = 0.087
Table S542. Gene #81: 'xp loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 185 | 161 | 159 |
| XP LOSS MUTATED | 40 | 38 | 21 |
| XP LOSS WILD-TYPE | 145 | 123 | 138 |
Figure S542. Get High-res Image Gene #81: 'xp loss' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'
P value = 0.0175 (Fisher's exact test), Q value = 0.046
Table S543. Gene #82: 'xq loss' versus Molecular Subtype #1: 'MRNA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 147 | 96 | 152 | 113 |
| XQ LOSS MUTATED | 19 | 28 | 26 | 19 |
| XQ LOSS WILD-TYPE | 128 | 68 | 126 | 94 |
Figure S543. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #1: 'MRNA_CNMF'
P value = 0.0254 (Fisher's exact test), Q value = 0.062
Table S544. Gene #82: 'xq loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 148 | 102 | 100 | 158 |
| XQ LOSS MUTATED | 18 | 28 | 18 | 28 |
| XQ LOSS WILD-TYPE | 130 | 74 | 82 | 130 |
Figure S544. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'
P value = 0.00269 (Fisher's exact test), Q value = 0.0095
Table S545. Gene #82: 'xq loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 184 | 237 | 64 | 165 |
| XQ LOSS MUTATED | 39 | 30 | 3 | 32 |
| XQ LOSS WILD-TYPE | 145 | 207 | 61 | 133 |
Figure S545. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #6: 'METHLYATION_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00045
Table S546. Gene #82: 'xq loss' versus Molecular Subtype #7: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 224 | 204 | 218 |
| XQ LOSS MUTATED | 34 | 20 | 56 |
| XQ LOSS WILD-TYPE | 190 | 184 | 162 |
Figure S546. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #7: 'RPPA_CNMF'
P value = 0.00111 (Fisher's exact test), Q value = 0.0043
Table S547. Gene #82: 'xq loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 233 | 235 | 192 |
| XQ LOSS MUTATED | 53 | 33 | 19 |
| XQ LOSS WILD-TYPE | 180 | 202 | 173 |
Figure S547. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #9: 'MRNASEQ_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00058
Table S548. Gene #82: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 137 | 107 | 183 | 82 |
| XQ LOSS MUTATED | 12 | 17 | 17 | 24 |
| XQ LOSS WILD-TYPE | 125 | 90 | 166 | 58 |
Figure S548. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #11: 'MIRSEQ_CNMF'
P value = 0.03 (Fisher's exact test), Q value = 0.071
Table S549. Gene #82: 'xq loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 91 | 137 | 188 | 89 |
| XQ LOSS MUTATED | 10 | 27 | 17 | 15 |
| XQ LOSS WILD-TYPE | 81 | 110 | 171 | 74 |
Figure S549. Get High-res Image Gene #82: 'xq loss' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'
-
Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
-
Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/GBMLGG-TP/19791524/transformed.cor.cli.txt
-
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/GBMLGG-TP/20148947/GBMLGG-TP.transferedmergedcluster.txt
-
Number of patients = 1090
-
Number of significantly arm-level cnvs = 82
-
Number of molecular subtypes = 14
-
Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.