Correlation between gene mutation status and molecular subtypes

Overview

Introduction

This pipeline computes the correlation between significantly recurrent gene mutations and molecular subtypes.

Summary

Testing the association between mutation status of 174 genes and 14 molecular subtypes across 796 patients, 194 significant findings detected with P value < 0.05 and Q value < 0.25.

IDH1 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
TP53 mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ATRX mutation correlated to 'MRNA_CNMF', 'MRNA_CHIERARCHICAL', 'MIR_CNMF', 'MIR_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
CIC mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
NF1 mutation correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PIK3R1 mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
NOTCH1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
IDH2 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
FUBP1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
RB1 mutation correlated to 'MRNA_CHIERARCHICAL', 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
PIK3CA mutation correlated to 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
PTEN mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ARID1A mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SLC26A3 mutation correlated to 'CN_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
NIPBL mutation correlated to 'METHLYATION_CNMF' and 'MIRSEQ_MATURE_CNMF'.
ZMIZ1 mutation correlated to 'MIRSEQ_MATURE_CNMF'.
NUDT11 mutation correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
CREBZF mutation correlated to 'METHLYATION_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
PLCG1 mutation correlated to 'CN_CNMF'.
STAG2 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CHIERARCHICAL'.
SEMG1 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
MUC17 mutation correlated to 'MRNA_CNMF' and 'MRNASEQ_CNMF'.
PDGFRA mutation correlated to 'MRNA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
NUP210L mutation correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CNMF'.
REN mutation correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
RBPJ mutation correlated to 'RPPA_CHIERARCHICAL'.
PTPN11 mutation correlated to 'MIR_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
RPL5 mutation correlated to 'METHLYATION_CNMF'.
BRAF mutation correlated to 'METHLYATION_CNMF'.
FAM47C mutation correlated to 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
TRERF1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SETD2 mutation correlated to 'MRNA_CNMF'.
DSP mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
KTELC1 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
TLR6 mutation correlated to 'METHLYATION_CNMF'.
EGFR mutation correlated to 'MRNA_CNMF', 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
ACADS mutation correlated to 'CN_CNMF'.
ATF7IP2 mutation correlated to 'CN_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
ZBTB20 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
ZDHHC4 mutation correlated to 'METHLYATION_CNMF'.
GRHL3 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
RASGRF2 mutation correlated to 'MIRSEQ_CHIERARCHICAL'.
LGALS13 mutation correlated to 'METHLYATION_CNMF'.
DOCK5 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
SMARCA4 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
QKI mutation correlated to 'CN_CNMF'.
TMPRSS6 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
MYT1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
PASD1 mutation correlated to 'MIR_CHIERARCHICAL'.
FMR1 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SOX13 mutation correlated to 'METHLYATION_CNMF'.
AK7 mutation correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
GABRA6 mutation correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
WDR90 mutation correlated to 'MIR_CNMF'.
NKPD1 mutation correlated to 'CN_CNMF'.
TP63 mutation correlated to 'RPPA_CNMF'.
NKX2-2 mutation correlated to 'MRNASEQ_CHIERARCHICAL'.
SEZ6L2 mutation correlated to 'RPPA_CNMF' and 'RPPA_CHIERARCHICAL'.
PRKCD mutation correlated to 'CN_CNMF'.
CHD8 mutation correlated to 'MRNASEQ_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
IGFN1 mutation correlated to 'METHLYATION_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
LRRC55 mutation correlated to 'MIRSEQ_CNMF'.
WDR63 mutation correlated to 'MRNASEQ_CNMF'.
KIF26B mutation correlated to 'METHLYATION_CNMF' and 'MIRSEQ_CHIERARCHICAL'.

Results

Overview of the results

Table 1. Get Full Table Overview of the association between mutation status of 174 genes and 14 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 194 significant findings detected.


		Clinical Features	MRNA CNMF	MRNA CHIERARCHICAL	MIR CNMF	MIR CHIERARCHICAL	CN CNMF	METHLYATION CNMF	RPPA CNMF	RPPA CHIERARCHICAL	MRNASEQ CNMF	MRNASEQ CHIERARCHICAL	MIRSEQ CNMF	MIRSEQ CHIERARCHICAL	MIRSEQ MATURE CNMF	MIRSEQ MATURE CHIERARCHICAL
	nMutated (%)	nWild-Type	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test	Fisher's exact test
IDH1	412 (52%)	384	6e-05 (0.00203)	1e-05 (0.000413)	2e-05 (0.000786)	0.00322 (0.0694)	1e-05 (0.000413)	1e-05 (0.000413)	0.023 (0.266)	0.121 (0.676)	1e-05 (0.000413)	1e-05 (0.000413)	3e-05 (0.00109)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)
TP53	328 (41%)	468	0.00087 (0.0228)	2e-05 (0.000786)	0.00085 (0.0228)	0.202 (0.85)	1e-05 (0.000413)	1e-05 (0.000413)	0.276 (0.954)	0.00902 (0.149)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	0.0538 (0.433)	1e-05 (0.000413)
ATRX	211 (27%)	585	0.00215 (0.0494)	1e-05 (0.000413)	0.00654 (0.12)	0.018 (0.232)	1e-05 (0.000413)	1e-05 (0.000413)	0.959 (1.00)	0.72 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	3e-05 (0.00109)	0.26 (0.952)	1e-05 (0.000413)
EGFR	109 (14%)	687	0.00713 (0.127)	0.0563 (0.447)	0.51 (1.00)	0.14 (0.742)	1e-05 (0.000413)	1e-05 (0.000413)	0.0725 (0.513)	0.0196 (0.246)	1e-05 (0.000413)	1e-05 (0.000413)	0.0107 (0.17)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)
NF1	62 (8%)	734	0.081 (0.557)	0.00047 (0.0135)	0.0244 (0.276)	0.931 (1.00)	0.00273 (0.0605)	1e-05 (0.000413)	0.899 (1.00)	3e-05 (0.00109)	6e-05 (0.00203)	0.00175 (0.0414)	0.338 (1.00)	0.00014 (0.00426)	0.00502 (0.0978)	1e-05 (0.000413)
CIC	109 (14%)	687					1e-05 (0.000413)	1e-05 (0.000413)	0.271 (0.952)	0.258 (0.952)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)
NOTCH1	42 (5%)	754					1e-05 (0.000413)	1e-05 (0.000413)	0.818 (1.00)	1 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	0.00021 (0.00624)	0.00404 (0.082)	0.00161 (0.0388)	0.00012 (0.0037)
FUBP1	47 (6%)	749					1e-05 (0.000413)	1e-05 (0.000413)	0.434 (1.00)	0.423 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	2e-05 (0.000786)	0.0009 (0.0233)	0.00767 (0.133)	1e-05 (0.000413)
PTEN	111 (14%)	685	0.116 (0.669)	0.0739 (0.52)	0.0274 (0.295)	0.647 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	0.192 (0.848)	0.115 (0.669)	1e-05 (0.000413)	1e-05 (0.000413)	0.00376 (0.0776)	1e-05 (0.000413)	1e-05 (0.000413)	1e-05 (0.000413)
IDH2	20 (3%)	776					0.00037 (0.0107)	7e-05 (0.0023)	0.454 (1.00)	0.133 (0.725)	3e-05 (0.00109)	1e-05 (0.000413)	0.00917 (0.15)	0.0007 (0.0192)	0.00305 (0.0663)	0.0468 (0.413)
RB1	30 (4%)	766	0.0337 (0.34)	0.0173 (0.227)	0.132 (0.721)	0.923 (1.00)	1e-05 (0.000413)	1e-05 (0.000413)	0.236 (0.905)	0.176 (0.832)	8e-05 (0.0026)	6e-05 (0.00203)	0.602 (1.00)	0.0324 (0.328)	0.782 (1.00)	0.246 (0.928)
STAG2	16 (2%)	780	0.391 (1.00)	0.698 (1.00)	0.715 (1.00)	0.591 (1.00)	0.0001 (0.00312)	0.00066 (0.0183)	0.854 (1.00)	0.0592 (0.457)	9e-05 (0.00285)	0.00113 (0.0283)	0.588 (1.00)	0.0139 (0.194)	0.474 (1.00)	0.237 (0.907)
PDGFRA	21 (3%)	775	0.0131 (0.189)	0.148 (0.77)	0.904 (1.00)	0.137 (0.739)	0.48 (1.00)	0.291 (0.971)	0.147 (0.769)	0.00749 (0.131)	0.00403 (0.082)	0.0234 (0.266)	0.00063 (0.0176)	0.00147 (0.0362)	0.851 (1.00)	0.186 (0.848)
SEMG1	11 (1%)	785	0.679 (1.00)	0.176 (0.832)	0.888 (1.00)	1 (1.00)	0.00099 (0.0254)	0.0129 (0.189)	0.546 (1.00)	0.785 (1.00)	0.0023 (0.0519)	0.00916 (0.15)	0.19 (0.848)	0.151 (0.778)	0.65 (1.00)	0.439 (1.00)
PTPN11	11 (1%)	785	1 (1.00)	0.785 (1.00)	0.00638 (0.118)	1 (1.00)	0.561 (1.00)	0.0316 (0.322)	1 (1.00)	0.26 (0.952)	0.228 (0.891)	0.268 (0.952)	0.222 (0.884)	0.00544 (0.103)	0.0161 (0.219)	0.00229 (0.0519)
ZBTB20	22 (3%)	774					7e-05 (0.0023)	3e-05 (0.00109)	0.0843 (0.57)	0.0931 (0.592)	9e-05 (0.00285)	4e-05 (0.00143)	0.158 (0.794)	0.0204 (0.254)	0.0411 (0.387)	0.0317 (0.322)
SMARCA4	27 (3%)	769					0.00202 (0.0469)	0.0163 (0.219)	0.274 (0.952)	0.8 (1.00)	0.00576 (0.108)	0.00973 (0.155)	0.304 (0.984)	0.245 (0.926)	0.873 (1.00)	0.166 (0.806)
GABRA6	15 (2%)	781	0.11 (0.655)	0.532 (1.00)	0.142 (0.749)	0.115 (0.669)	0.00352 (0.0733)	0.0093 (0.151)	0.489 (1.00)	0.924 (1.00)	0.00114 (0.0283)	0.0918 (0.588)	0.59 (1.00)	0.0132 (0.189)	0.474 (1.00)	0.238 (0.907)
PIK3CA	71 (9%)	725	0.953 (1.00)	0.288 (0.971)	0.291 (0.971)	0.861 (1.00)	0.667 (1.00)	1e-05 (0.000413)	0.372 (1.00)	0.38 (1.00)	0.425 (1.00)	0.0368 (0.358)	0.00952 (0.153)	0.039 (0.372)	0.328 (1.00)	0.00087 (0.0228)
SLC26A3	11 (1%)	785	0.941 (1.00)	0.767 (1.00)	0.466 (1.00)	0.366 (1.00)	0.0111 (0.174)	0.0221 (0.264)	0.0988 (0.619)	0.0647 (0.482)	0.00459 (0.0909)	0.00617 (0.115)	0.0458 (0.412)	0.0278 (0.296)	1 (1.00)	0.185 (0.848)
FAM47C	23 (3%)	773	0.479 (1.00)	0.0582 (0.456)	0.403 (1.00)	0.843 (1.00)	0.329 (1.00)	0.541 (1.00)	0.914 (1.00)	0.757 (1.00)	0.0512 (0.428)	0.0047 (0.0923)	0.614 (1.00)	0.0916 (0.588)	0.00856 (0.143)	0.00345 (0.0724)
PIK3R1	54 (7%)	742	0.751 (1.00)	0.191 (0.848)	0.196 (0.848)	0.528 (1.00)	0.0171 (0.225)	5e-05 (0.00177)	1 (1.00)	0.918 (1.00)	0.248 (0.934)	0.926 (1.00)	0.0869 (0.578)	0.582 (1.00)	0.962 (1.00)	0.63 (1.00)
NIPBL	20 (3%)	776					0.028 (0.296)	0.00021 (0.00624)	0.234 (0.904)	0.57 (1.00)	0.0527 (0.428)	0.0481 (0.42)	0.449 (1.00)	0.172 (0.819)	0.0116 (0.179)	0.0592 (0.457)
NUDT11	11 (1%)	785					0.0165 (0.22)	0.35 (1.00)	0.64 (1.00)	0.294 (0.971)	0.38 (1.00)	0.015 (0.206)	0.0261 (0.289)	0.918 (1.00)	0.17 (0.813)	0.295 (0.971)
CREBZF	9 (1%)	787					0.0371 (0.359)	0.0006 (0.017)	0.331 (1.00)	0.431 (1.00)	0.0213 (0.262)	0.0687 (0.504)	0.201 (0.848)	0.0139 (0.194)	0.117 (0.669)	0.0532 (0.43)
MUC17	49 (6%)	747	0.0128 (0.189)	0.191 (0.848)	0.707 (1.00)	0.704 (1.00)	0.158 (0.794)	0.35 (1.00)	0.36 (1.00)	0.258 (0.952)	0.0131 (0.189)	0.209 (0.857)	0.0267 (0.291)	0.0399 (0.379)	0.0278 (0.296)	0.0616 (0.47)
NUP210L	12 (2%)	784	0.81 (1.00)	0.427 (1.00)	0.411 (1.00)	0.36 (1.00)	0.199 (0.848)	0.0128 (0.189)	0.587 (1.00)	1 (1.00)	0.0163 (0.219)	0.205 (0.854)	0.4 (1.00)	0.0765 (0.532)	0.164 (0.805)	0.357 (1.00)
REN	7 (1%)	789	0.477 (1.00)	0.417 (1.00)	0.0734 (0.518)	0.511 (1.00)	0.00281 (0.0617)	0.00269 (0.0601)	0.458 (1.00)	0.887 (1.00)	0.201 (0.848)	0.786 (1.00)
ATF7IP2	8 (1%)	788	0.912 (1.00)	1 (1.00)	0.285 (0.969)	0.106 (0.647)	0.00339 (0.072)	0.316 (0.987)	0.873 (1.00)	1 (1.00)	0.0222 (0.264)	0.103 (0.635)	1 (1.00)	0.00849 (0.143)	0.652 (1.00)	0.0886 (0.585)
DOCK5	20 (3%)	776	0.26 (0.952)	0.908 (1.00)	0.0593 (0.457)	0.299 (0.974)	0.0253 (0.284)	0.0346 (0.347)	0.0267 (0.291)	0.165 (0.806)	0.0121 (0.185)	0.00543 (0.103)	0.0384 (0.368)	0.0663 (0.489)	0.727 (1.00)	0.46 (1.00)
TMPRSS6	9 (1%)	787	0.665 (1.00)	0.705 (1.00)	0.662 (1.00)	0.267 (0.952)	0.05 (0.427)	0.0237 (0.268)	0.226 (0.888)	0.115 (0.669)	0.00152 (0.037)	0.00695 (0.125)	0.191 (0.848)	0.153 (0.78)	0.65 (1.00)	0.438 (1.00)
AK7	9 (1%)	787	0.138 (0.739)	0.127 (0.694)	0.59 (1.00)	0.235 (0.905)	0.0513 (0.428)	0.0719 (0.512)	0.804 (1.00)	0.494 (1.00)	0.164 (0.806)	0.0861 (0.576)	0.0811 (0.557)	0.00168 (0.0401)	0.269 (0.952)	0.0011 (0.0279)
SEZ6L2	7 (1%)	789	0.837 (1.00)	0.472 (1.00)	0.101 (0.631)	0.124 (0.687)	0.473 (1.00)	0.884 (1.00)	0.0113 (0.177)	0.0041 (0.0825)	0.168 (0.81)	1 (1.00)	0.28 (0.954)	0.0984 (0.618)	0.0303 (0.311)	0.317 (0.987)
CHD8	11 (1%)	785	0.699 (1.00)	0.532 (1.00)	0.135 (0.73)	0.646 (1.00)	0.199 (0.848)	0.0504 (0.428)	0.293 (0.971)	0.479 (1.00)	0.0169 (0.224)	0.0186 (0.237)
IGFN1	9 (1%)	787	1 (1.00)	1 (1.00)	0.772 (1.00)	0.558 (1.00)	0.124 (0.687)	0.00086 (0.0228)	0.871 (1.00)	0.644 (1.00)	0.0224 (0.264)	0.19 (0.848)	1 (1.00)	0.00813 (0.138)	0.412 (1.00)	0.149 (0.774)
KIF26B	6 (1%)	790					0.695 (1.00)	0.0133 (0.189)	0.872 (1.00)	0.543 (1.00)	0.123 (0.687)	0.884 (1.00)	1 (1.00)	0.0034 (0.072)	0.456 (1.00)	0.0847 (0.57)
ARID1A	22 (3%)	774					0.0204 (0.254)	0.022 (0.264)	0.411 (1.00)	1 (1.00)	0.0255 (0.285)	0.00531 (0.103)	0.316 (0.987)	0.605 (1.00)	0.0827 (0.563)	0.0295 (0.306)
ZMIZ1	13 (2%)	783	0.505 (1.00)	0.912 (1.00)	0.643 (1.00)	0.443 (1.00)	0.236 (0.905)	0.328 (1.00)	0.0647 (0.482)	0.118 (0.671)	0.869 (1.00)	0.342 (1.00)	0.478 (1.00)	0.679 (1.00)	0.0187 (0.237)	0.419 (1.00)
PLCG1	11 (1%)	785	0.641 (1.00)	0.928 (1.00)	0.871 (1.00)	0.842 (1.00)	0.0114 (0.177)	0.21 (0.857)	0.543 (1.00)	1 (1.00)	0.573 (1.00)	0.269 (0.952)	0.0263 (0.29)	0.0655 (0.487)	0.0545 (0.435)	0.15 (0.775)
RBPJ	7 (1%)	789					0.108 (0.652)	0.0397 (0.377)	0.381 (1.00)	0.00677 (0.123)	0.0269 (0.291)	0.142 (0.749)	0.329 (1.00)	0.0287 (0.301)	0.118 (0.67)	0.444 (1.00)
RPL5	10 (1%)	786	0.381 (1.00)	0.51 (1.00)	0.869 (1.00)	0.469 (1.00)	0.261 (0.952)	0.014 (0.194)	0.515 (1.00)	0.803 (1.00)	0.0223 (0.264)	0.188 (0.848)	0.0894 (0.586)	0.0527 (0.428)	1 (1.00)	0.51 (1.00)
BRAF	11 (1%)	785	0.766 (1.00)	0.713 (1.00)	0.317 (0.988)	0.0288 (0.301)	0.411 (1.00)	0.00025 (0.00734)	0.413 (1.00)	0.291 (0.971)	0.0499 (0.427)	0.36 (1.00)	0.263 (0.952)	0.0902 (0.586)	0.0632 (0.478)	0.196 (0.848)
TRERF1	7 (1%)	789					0.307 (0.985)	0.861 (1.00)	0.791 (1.00)	0.772 (1.00)	1 (1.00)	0.0182 (0.233)	0.387 (1.00)	0.759 (1.00)	0.104 (0.636)	0.355 (1.00)
SETD2	13 (2%)	783	0.00538 (0.103)	0.35 (1.00)	0.459 (1.00)	1 (1.00)	0.624 (1.00)	0.176 (0.832)	1 (1.00)	0.522 (1.00)	0.108 (0.652)	0.383 (1.00)	0.602 (1.00)	0.091 (0.586)	0.854 (1.00)	0.379 (1.00)
DSP	21 (3%)	775	0.489 (1.00)	0.962 (1.00)	0.572 (1.00)	0.0719 (0.512)	0.0708 (0.511)	0.0453 (0.412)	0.34 (1.00)	0.587 (1.00)	0.672 (1.00)	0.728 (1.00)	0.712 (1.00)	0.0163 (0.219)	0.914 (1.00)	0.55 (1.00)
KTELC1	5 (1%)	791					0.2 (0.848)	0.296 (0.971)	1 (1.00)	0.38 (1.00)	0.633 (1.00)	0.194 (0.848)	0.116 (0.669)	0.00699 (0.125)	1 (1.00)	0.109 (0.654)
TLR6	8 (1%)	788	0.247 (0.932)	0.0479 (0.42)	0.431 (1.00)	0.294 (0.971)	0.125 (0.687)	0.00824 (0.139)	1 (1.00)	1 (1.00)	0.334 (1.00)	0.573 (1.00)	0.278 (0.954)	0.232 (0.9)	0.412 (1.00)	0.512 (1.00)
ACADS	5 (1%)	791	0.416 (1.00)	0.35 (1.00)	0.34 (1.00)	0.793 (1.00)	0.00812 (0.138)	0.0464 (0.412)
ZDHHC4	4 (1%)	792			0.162 (0.804)	1 (1.00)	0.184 (0.848)	0.0124 (0.186)	1 (1.00)	0.629 (1.00)
GRHL3	8 (1%)	788	0.913 (1.00)	1 (1.00)	1 (1.00)	0.446 (1.00)	0.166 (0.808)	0.0798 (0.552)	0.75 (1.00)	0.639 (1.00)	0.0225 (0.264)	0.443 (1.00)	0.589 (1.00)	0.0133 (0.189)	0.163 (0.804)	0.236 (0.905)
RASGRF2	6 (1%)	790					0.696 (1.00)	0.209 (0.857)	1 (1.00)	1 (1.00)	0.335 (1.00)	0.67 (1.00)	0.0808 (0.557)	0.0133 (0.189)	0.839 (1.00)	0.635 (1.00)
LGALS13	4 (1%)	792					1 (1.00)	0.0176 (0.229)			1 (1.00)	0.782 (1.00)	0.0486 (0.42)	0.313 (0.985)	0.11 (0.655)	0.224 (0.884)
QKI	6 (1%)	790	0.266 (0.952)	0.059 (0.457)	0.764 (1.00)	1 (1.00)	0.00734 (0.13)	0.313 (0.985)	1 (1.00)	0.569 (1.00)	0.644 (1.00)	0.272 (0.952)
MYT1	6 (1%)	790					0.137 (0.738)	0.267 (0.952)			0.879 (1.00)	0.018 (0.232)	0.427 (1.00)	0.755 (1.00)	0.451 (1.00)	0.942 (1.00)
PASD1	8 (1%)	788			0.286 (0.969)	0.00768 (0.133)	0.522 (1.00)	0.682 (1.00)	0.9 (1.00)	0.897 (1.00)	0.11 (0.655)	0.312 (0.985)	0.914 (1.00)	0.423 (1.00)	0.0755 (0.529)	0.758 (1.00)
FMR1	5 (1%)	791					0.199 (0.848)	0.778 (1.00)	0.748 (1.00)	1 (1.00)	0.334 (1.00)	0.00189 (0.0443)	0.243 (0.92)	0.355 (1.00)	0.334 (1.00)	1 (1.00)
SOX13	5 (1%)	791			0.779 (1.00)	1 (1.00)	0.112 (0.662)	0.0124 (0.186)	0.541 (1.00)	1 (1.00)	0.401 (1.00)	1 (1.00)
WDR90	9 (1%)	787	0.153 (0.78)	0.364 (1.00)	0.00944 (0.152)	0.56 (1.00)	0.366 (1.00)	0.509 (1.00)	0.708 (1.00)	0.114 (0.669)	0.0425 (0.396)	0.387 (1.00)	0.52 (1.00)	0.794 (1.00)	0.207 (0.857)	1 (1.00)
NKPD1	3 (0%)	793					0.0143 (0.196)	0.191 (0.848)	0.431 (1.00)	0.19 (0.848)	1 (1.00)	0.38 (1.00)	0.678 (1.00)	0.793 (1.00)	0.207 (0.857)	0.778 (1.00)
TP63	9 (1%)	787	1 (1.00)	0.733 (1.00)	0.403 (1.00)	0.646 (1.00)	0.368 (1.00)	0.0618 (0.471)	0.0124 (0.186)	0.273 (0.952)	0.0426 (0.396)	0.0576 (0.453)	0.234 (0.904)	0.429 (1.00)	0.0637 (0.479)	0.265 (0.952)
NKX2-2	6 (1%)	790					0.136 (0.736)	0.647 (1.00)	0.787 (1.00)	0.885 (1.00)	0.389 (1.00)	0.0187 (0.237)	0.802 (1.00)	1 (1.00)	0.0692 (0.505)	0.888 (1.00)
PRKCD	3 (0%)	793	0.17 (0.812)	0.0822 (0.562)	0.164 (0.805)	1 (1.00)	0.00418 (0.0835)
LRRC55	9 (1%)	787	0.375 (1.00)	0.537 (1.00)	0.334 (1.00)	0.868 (1.00)	0.161 (0.802)	0.249 (0.934)	1 (1.00)	0.542 (1.00)	0.842 (1.00)	0.696 (1.00)	0.0135 (0.19)	0.794 (1.00)	0.208 (0.857)	1 (1.00)
WDR63	9 (1%)	787	0.0956 (0.603)	0.601 (1.00)	0.675 (1.00)	0.139 (0.742)	0.165 (0.806)	0.071 (0.511)	0.876 (1.00)	0.299 (0.974)	0.0119 (0.182)	0.0301 (0.311)	0.912 (1.00)	0.0268 (0.291)	1 (1.00)	0.432 (1.00)
TCF12	19 (2%)	777	1 (1.00)	0.481 (1.00)	0.645 (1.00)	0.257 (0.952)	0.221 (0.884)	0.796 (1.00)	0.738 (1.00)	0.383 (1.00)	0.13 (0.71)	0.294 (0.971)	0.696 (1.00)	0.517 (1.00)	1 (1.00)	0.514 (1.00)
STK19	11 (1%)	785					0.589 (1.00)	0.473 (1.00)	0.119 (0.672)	0.629 (1.00)	0.351 (1.00)	0.864 (1.00)	0.167 (0.809)	0.544 (1.00)	0.923 (1.00)	0.843 (1.00)
GAGE2A	8 (1%)	788					0.322 (0.998)	0.667 (1.00)	0.825 (1.00)	0.288 (0.971)	0.905 (1.00)	0.612 (1.00)	0.656 (1.00)	0.903 (1.00)	0.822 (1.00)	0.923 (1.00)
ZNF709	6 (1%)	790					1 (1.00)	1 (1.00)	0.872 (1.00)	0.641 (1.00)	0.86 (1.00)	0.869 (1.00)	1 (1.00)	0.683 (1.00)	0.273 (0.952)	1 (1.00)
IRS4	10 (1%)	786	0.116 (0.669)	1 (1.00)	0.0523 (0.428)	0.121 (0.676)	0.77 (1.00)	0.693 (1.00)	0.466 (1.00)	0.706 (1.00)	0.671 (1.00)	0.238 (0.907)	0.413 (1.00)	0.691 (1.00)	0.268 (0.952)	1 (1.00)
NKD2	4 (1%)	792					1 (1.00)	1 (1.00)			0.397 (1.00)	1 (1.00)	0.368 (1.00)	1 (1.00)	1 (1.00)	0.837 (1.00)
MED9	3 (0%)	793					1 (1.00)	0.472 (1.00)	0.0351 (0.35)	0.265 (0.952)	0.296 (0.971)	1 (1.00)	0.879 (1.00)	0.796 (1.00)	0.653 (1.00)	0.51 (1.00)
HTRA2	5 (1%)	791					0.2 (0.848)	0.41 (1.00)	0.28 (0.954)	0.836 (1.00)	0.863 (1.00)	0.868 (1.00)	0.348 (1.00)	0.727 (1.00)	0.555 (1.00)	0.468 (1.00)
BCOR	22 (3%)	774	0.64 (1.00)	0.363 (1.00)	0.101 (0.631)	0.604 (1.00)	1 (1.00)	0.653 (1.00)	0.441 (1.00)	0.889 (1.00)	0.277 (0.954)	0.364 (1.00)	0.792 (1.00)	0.584 (1.00)	0.719 (1.00)	0.949 (1.00)
DDX5	9 (1%)	787	0.211 (0.862)	1 (1.00)	0.538 (1.00)	0.445 (1.00)	1 (1.00)	0.677 (1.00)	0.465 (1.00)	0.565 (1.00)	0.88 (1.00)	0.589 (1.00)	0.263 (0.952)	0.441 (1.00)	0.0276 (0.296)	0.316 (0.987)
KDR	13 (2%)	783	0.205 (0.854)	0.657 (1.00)	0.278 (0.954)	0.511 (1.00)	0.191 (0.848)	0.0369 (0.358)	0.784 (1.00)	0.0952 (0.602)	0.102 (0.632)	0.672 (1.00)	0.263 (0.952)	0.023 (0.266)	0.239 (0.911)	0.198 (0.848)
NRAS	5 (1%)	791					0.669 (1.00)	0.252 (0.938)	0.21 (0.857)	0.855 (1.00)	0.109 (0.654)	0.312 (0.985)	0.305 (0.984)	0.682 (1.00)	0.333 (1.00)	0.759 (1.00)
TPX2	7 (1%)	789					0.731 (1.00)	0.643 (1.00)	0.699 (1.00)	1 (1.00)	1 (1.00)	0.591 (1.00)	0.492 (1.00)	0.0713 (0.512)	0.169 (0.81)	0.316 (0.987)
EMG1	6 (1%)	790					0.135 (0.733)	0.372 (1.00)	0.226 (0.888)	0.774 (1.00)	0.143 (0.752)	0.0965 (0.607)	0.408 (1.00)	0.432 (1.00)	0.525 (1.00)	0.725 (1.00)
MX2	9 (1%)	787	0.601 (1.00)	0.84 (1.00)	0.448 (1.00)	0.446 (1.00)	0.364 (1.00)	0.719 (1.00)	0.876 (1.00)	0.404 (1.00)	1 (1.00)	1 (1.00)	0.367 (1.00)	1 (1.00)	1 (1.00)	0.638 (1.00)
MYST4	12 (2%)	784					0.113 (0.665)	0.101 (0.631)	0.0826 (0.563)	0.276 (0.954)	0.412 (1.00)	0.201 (0.848)	0.204 (0.854)	1 (1.00)	0.0636 (0.479)	0.612 (1.00)
SRPX	4 (1%)	792					0.65 (1.00)	0.283 (0.962)	0.554 (1.00)	0.683 (1.00)	0.557 (1.00)	0.57 (1.00)	0.274 (0.952)	0.198 (0.848)	0.393 (1.00)	0.063 (0.478)
TNRC18	11 (1%)	785					0.294 (0.971)	0.393 (1.00)	0.61 (1.00)	0.546 (1.00)	0.217 (0.876)	0.641 (1.00)	0.678 (1.00)	0.377 (1.00)	0.821 (1.00)	0.58 (1.00)
SLC6A3	12 (2%)	784	0.62 (1.00)	0.697 (1.00)	0.396 (1.00)	1 (1.00)	0.597 (1.00)	0.88 (1.00)	0.107 (0.65)	0.0658 (0.487)	1 (1.00)	0.674 (1.00)	0.174 (0.825)	0.507 (1.00)	0.702 (1.00)	0.537 (1.00)
ZNF292	17 (2%)	779	0.477 (1.00)	0.223 (0.884)	0.396 (1.00)	0.312 (0.985)	0.251 (0.938)	0.169 (0.81)	0.363 (1.00)	0.799 (1.00)	0.156 (0.793)	0.0867 (0.578)	0.426 (1.00)	0.293 (0.971)	0.0837 (0.568)	0.0543 (0.435)
TMEM216	3 (0%)	793					0.313 (0.985)	0.844 (1.00)	0.434 (1.00)	0.189 (0.848)	0.296 (0.971)	0.633 (1.00)	0.522 (1.00)	0.601 (1.00)	0.305 (0.984)	0.67 (1.00)
ARID2	13 (2%)	783					0.456 (1.00)	0.942 (1.00)	1 (1.00)	0.61 (1.00)	1 (1.00)	0.145 (0.762)	0.602 (1.00)	0.343 (1.00)	0.479 (1.00)	0.46 (1.00)
FAM83D	5 (1%)	791					0.4 (1.00)	0.474 (1.00)	0.215 (0.873)	0.785 (1.00)	0.843 (1.00)	0.825 (1.00)	1 (1.00)	0.0533 (0.43)	1 (1.00)	0.777 (1.00)
NEU2	8 (1%)	788	0.217 (0.876)	0.549 (1.00)	0.776 (1.00)	1 (1.00)	1 (1.00)	0.85 (1.00)	0.0897 (0.586)	0.171 (0.814)	1 (1.00)	0.346 (1.00)	0.305 (0.984)	1 (1.00)	0.457 (1.00)	0.713 (1.00)
LUM	7 (1%)	789	0.781 (1.00)	0.117 (0.669)	0.72 (1.00)	0.713 (1.00)	0.169 (0.81)	0.312 (0.985)	0.698 (1.00)	1 (1.00)	0.398 (1.00)	1 (1.00)
WRN	6 (1%)	790					0.446 (1.00)	0.0487 (0.42)	0.874 (1.00)	0.641 (1.00)	1 (1.00)	0.518 (1.00)	0.0566 (0.447)	1 (1.00)	0.0447 (0.409)	0.453 (1.00)
TMEM184A	3 (0%)	793					1 (1.00)	0.353 (1.00)	1 (1.00)	0.787 (1.00)	0.202 (0.85)	0.785 (1.00)	0.88 (1.00)	0.232 (0.899)	0.412 (1.00)	0.512 (1.00)
ZNF512B	5 (1%)	791					0.199 (0.848)	0.85 (1.00)	1 (1.00)	1 (1.00)	0.861 (1.00)	0.34 (1.00)	1 (1.00)	1 (1.00)	0.454 (1.00)	0.245 (0.926)
PRCP	5 (1%)	791					0.185 (0.848)	0.0466 (0.413)	0.661 (1.00)	0.268 (0.952)	0.402 (1.00)	0.49 (1.00)
DNMT3A	10 (1%)	786					0.0317 (0.322)	1 (1.00)	0.119 (0.672)	0.351 (1.00)	0.222 (0.884)	0.0859 (0.576)	0.481 (1.00)	0.045 (0.411)	0.922 (1.00)	0.972 (1.00)
PROKR2	9 (1%)	787	0.602 (1.00)	0.729 (1.00)	0.719 (1.00)	0.184 (0.848)	0.0517 (0.428)	0.251 (0.938)	0.321 (0.996)	0.483 (1.00)	0.0904 (0.586)	0.0401 (0.379)	0.281 (0.957)	0.791 (1.00)	1 (1.00)	0.778 (1.00)
C10ORF76	4 (1%)	792					0.651 (1.00)	0.0949 (0.602)			0.158 (0.794)	0.824 (1.00)	0.328 (1.00)	0.0515 (0.428)	0.411 (1.00)	0.511 (1.00)
KRT15	8 (1%)	788					0.737 (1.00)	0.485 (1.00)	0.846 (1.00)	0.838 (1.00)	0.457 (1.00)	1 (1.00)	0.516 (1.00)	0.866 (1.00)	1 (1.00)	1 (1.00)
G6PC	7 (1%)	789					0.732 (1.00)	0.28 (0.954)	0.322 (0.998)	0.8 (1.00)	0.799 (1.00)	1 (1.00)	0.428 (1.00)	0.15 (0.775)	0.294 (0.971)	0.765 (1.00)
SERPING1	4 (1%)	792					0.65 (1.00)	0.802 (1.00)	1 (1.00)	0.14 (0.742)	0.297 (0.973)	0.635 (1.00)	0.681 (1.00)	0.601 (1.00)	0.41 (1.00)	0.584 (1.00)
CPEB4	7 (1%)	789					0.31 (0.985)	0.457 (1.00)	0.876 (1.00)	0.771 (1.00)	0.801 (1.00)	0.577 (1.00)	0.767 (1.00)	1 (1.00)	0.454 (1.00)	0.393 (1.00)
EEF1A1	8 (1%)	788	0.398 (1.00)	0.194 (0.848)	0.539 (1.00)	0.446 (1.00)	0.125 (0.687)	0.476 (1.00)	0.0373 (0.359)	0.682 (1.00)	0.223 (0.884)	0.446 (1.00)	0.0219 (0.264)	0.198 (0.848)	1 (1.00)	0.837 (1.00)
PDHA1	6 (1%)	790					1 (1.00)	0.544 (1.00)	0.878 (1.00)	0.301 (0.977)	0.878 (1.00)	0.883 (1.00)	0.928 (1.00)	0.848 (1.00)	0.533 (1.00)	0.398 (1.00)
FAM123C	11 (1%)	785	0.0233 (0.266)	0.559 (1.00)	0.848 (1.00)	0.119 (0.671)	0.199 (0.848)	0.124 (0.687)	0.71 (1.00)	0.273 (0.952)	0.116 (0.669)	0.104 (0.636)	0.0689 (0.504)	0.264 (0.952)	0.396 (1.00)	0.141 (0.746)
KRAS	4 (1%)	792					0.648 (1.00)	1 (1.00)	1 (1.00)	0.364 (1.00)	1 (1.00)	0.785 (1.00)
OAS2	4 (1%)	792	1 (1.00)	0.702 (1.00)	0.606 (1.00)	0.791 (1.00)	0.187 (0.848)				0.272 (0.952)	0.104 (0.636)
MAP3K1	9 (1%)	787	1 (1.00)	0.73 (1.00)	0.807 (1.00)	0.645 (1.00)	0.162 (0.803)	0.542 (1.00)	0.541 (1.00)	0.455 (1.00)	0.165 (0.806)	0.272 (0.952)	0.331 (1.00)	0.0517 (0.428)	0.207 (0.857)	1 (1.00)
TRPV6	13 (2%)	783	0.335 (1.00)	0.225 (0.887)	0.191 (0.848)	1 (1.00)	0.45 (1.00)	0.676 (1.00)	0.411 (1.00)	0.432 (1.00)	0.0769 (0.533)	0.506 (1.00)	0.696 (1.00)	0.505 (1.00)	0.605 (1.00)	0.495 (1.00)
MAP3K12	6 (1%)	790					0.448 (1.00)	0.547 (1.00)	0.626 (1.00)	1 (1.00)	0.448 (1.00)	0.339 (1.00)	0.489 (1.00)	0.444 (1.00)	0.166 (0.808)	0.666 (1.00)
TLR7	10 (1%)	786	0.173 (0.82)	0.477 (1.00)	0.761 (1.00)	0.672 (1.00)	0.559 (1.00)	0.128 (0.7)	0.586 (1.00)	0.588 (1.00)	0.676 (1.00)	0.733 (1.00)	1 (1.00)	0.757 (1.00)	0.295 (0.971)	0.355 (1.00)
TREML2	7 (1%)	789	0.0887 (0.585)	1 (1.00)	0.538 (1.00)	0.812 (1.00)	1 (1.00)	0.801 (1.00)	1 (1.00)	1 (1.00)	0.336 (1.00)	0.669 (1.00)	0.522 (1.00)	0.793 (1.00)	0.204 (0.854)	1 (1.00)
MACC1	8 (1%)	788	0.783 (1.00)	0.114 (0.669)	0.182 (0.848)	0.259 (0.952)	0.223 (0.884)	0.143 (0.752)	0.0893 (0.586)	0.189 (0.848)	0.222 (0.884)	0.0567 (0.447)	0.192 (0.848)	0.197 (0.848)	0.841 (1.00)	0.638 (1.00)
AOX1	8 (1%)	788	0.431 (1.00)	0.273 (0.952)	0.118 (0.671)	0.185 (0.848)	0.222 (0.884)	0.545 (1.00)	0.541 (1.00)	0.885 (1.00)	0.0923 (0.589)	0.107 (0.65)	0.0442 (0.406)	0.0281 (0.297)	0.27 (0.952)	0.919 (1.00)
HEATR3	4 (1%)	792					0.649 (1.00)	0.299 (0.974)	0.777 (1.00)	0.628 (1.00)	0.645 (1.00)	1 (1.00)
KRT13	6 (1%)	790	0.784 (1.00)	0.115 (0.669)	1 (1.00)	0.072 (0.512)	0.251 (0.938)	0.543 (1.00)			0.157 (0.794)	0.824 (1.00)	0.33 (1.00)	0.0523 (0.428)	1 (1.00)	0.151 (0.778)
CNOT1	8 (1%)	788					0.319 (0.993)	0.823 (1.00)	1 (1.00)	1 (1.00)	0.825 (1.00)	0.0484 (0.42)	0.766 (1.00)	0.691 (1.00)	0.804 (1.00)	0.681 (1.00)
ESR2	6 (1%)	790	0.48 (1.00)	0.701 (1.00)	0.781 (1.00)	0.435 (1.00)	1 (1.00)	0.806 (1.00)	1 (1.00)	0.747 (1.00)	0.56 (1.00)	0.694 (1.00)	0.189 (0.848)	0.43 (1.00)	1 (1.00)	1 (1.00)
PAK1	3 (0%)	793					1 (1.00)	0.548 (1.00)	0.777 (1.00)	0.631 (1.00)
SLC35A2	3 (0%)	793					1 (1.00)				1 (1.00)	1 (1.00)
CDKN2A	6 (1%)	790					1 (1.00)	1 (1.00)	0.552 (1.00)	0.683 (1.00)	0.292 (0.971)	0.386 (1.00)	0.0217 (0.264)	0.262 (0.952)	0.118 (0.671)	0.76 (1.00)
TYRP1	6 (1%)	790					1 (1.00)	0.925 (1.00)	1 (1.00)	0.364 (1.00)	0.777 (1.00)	0.388 (1.00)	0.4 (1.00)	0.342 (1.00)	0.695 (1.00)	0.36 (1.00)
CD99L2	5 (1%)	791					0.669 (1.00)	0.2 (0.848)	1 (1.00)	0.834 (1.00)	1 (1.00)	0.739 (1.00)	0.218 (0.877)	1 (1.00)	0.695 (1.00)	0.58 (1.00)
MORN5	3 (0%)	793					0.575 (1.00)		0.218 (0.877)	0.481 (1.00)
NAP1L2	6 (1%)	790					1 (1.00)	0.659 (1.00)	0.697 (1.00)	0.249 (0.935)	0.861 (1.00)	0.868 (1.00)	1 (1.00)	0.832 (1.00)	1 (1.00)	1 (1.00)
CD44	6 (1%)	790	0.698 (1.00)	0.264 (0.952)	0.287 (0.971)	0.792 (1.00)	0.697 (1.00)	1 (1.00)	0.0368 (0.358)	0.682 (1.00)	0.204 (0.854)	0.633 (1.00)	0.682 (1.00)	0.233 (0.901)	0.207 (0.857)	1 (1.00)
OR52M1	8 (1%)	788	0.505 (1.00)	0.605 (1.00)	0.0886 (0.585)	0.0605 (0.465)	0.222 (0.884)	0.38 (1.00)	0.703 (1.00)	0.776 (1.00)	0.574 (1.00)	0.273 (0.952)	0.765 (1.00)	1 (1.00)	1 (1.00)	0.839 (1.00)
ROBO3	5 (1%)	791					0.2 (0.848)	0.581 (1.00)	0.278 (0.954)	0.457 (1.00)	0.275 (0.954)	0.339 (1.00)	0.4 (1.00)	0.287 (0.971)	1 (1.00)	0.927 (1.00)
MYO5A	5 (1%)	791					0.399 (1.00)	0.0358 (0.354)	0.382 (1.00)	0.187 (0.848)	0.158 (0.794)	0.824 (1.00)	0.764 (1.00)	0.341 (1.00)	0.474 (1.00)	0.524 (1.00)
KRT3	4 (1%)	792					1 (1.00)	1 (1.00)	0.777 (1.00)	0.627 (1.00)	0.398 (1.00)	0.696 (1.00)	0.274 (0.952)	0.197 (0.848)	0.394 (1.00)	0.213 (0.868)
GEFT	4 (1%)	792					0.185 (0.848)	0.0459 (0.412)			0.0226 (0.264)	0.102 (0.632)	0.189 (0.848)	0.152 (0.779)	0.651 (1.00)	0.439 (1.00)
POM121	6 (1%)	790					0.444 (1.00)	0.314 (0.985)	0.279 (0.954)	0.139 (0.742)	0.539 (1.00)	0.618 (1.00)	0.592 (1.00)	0.338 (1.00)	0.697 (1.00)	0.523 (1.00)
CMA1	3 (0%)	793					1 (1.00)	0.548 (1.00)	1 (1.00)	1 (1.00)
PLXNA3	10 (1%)	786					0.386 (1.00)	0.352 (1.00)	0.0907 (0.586)	0.52 (1.00)	0.438 (1.00)	0.614 (1.00)	0.351 (1.00)	0.23 (0.895)	0.482 (1.00)	0.877 (1.00)
EPS8L1	4 (1%)	792					0.65 (1.00)	0.547 (1.00)	0.109 (0.654)	0.0615 (0.47)	0.401 (1.00)	1 (1.00)
PRG4	10 (1%)	786					0.393 (1.00)	1 (1.00)	0.0703 (0.511)	0.434 (1.00)	0.329 (1.00)	0.194 (0.848)	0.404 (1.00)	0.901 (1.00)	0.609 (1.00)	0.72 (1.00)
RFX4	6 (1%)	790					1 (1.00)	0.209 (0.857)	0.279 (0.954)	0.836 (1.00)	1 (1.00)	0.312 (0.985)	0.644 (1.00)	0.684 (1.00)	0.334 (1.00)	0.759 (1.00)
GFRA4	3 (0%)	793					0.572 (1.00)	0.546 (1.00)
TNFRSF9	4 (1%)	792					0.647 (1.00)	0.0671 (0.494)	0.699 (1.00)	0.57 (1.00)	1 (1.00)	1 (1.00)	0.599 (1.00)	0.793 (1.00)	0.651 (1.00)	0.512 (1.00)
EGR1	5 (1%)	791	0.701 (1.00)	0.785 (1.00)	0.24 (0.912)	0.195 (0.848)	1 (1.00)		0.11 (0.655)	0.064 (0.48)	0.159 (0.794)	0.823 (1.00)
FAM126B	8 (1%)	788	0.399 (1.00)	0.0293 (0.305)	0.644 (1.00)	0.443 (1.00)	0.0365 (0.358)	0.802 (1.00)	0.705 (1.00)	0.771 (1.00)	0.272 (0.952)	0.694 (1.00)	0.196 (0.848)	0.197 (0.848)	0.838 (1.00)	0.697 (1.00)
SON	9 (1%)	787					0.536 (1.00)	0.509 (1.00)	0.231 (0.899)	0.394 (1.00)	0.837 (1.00)	0.838 (1.00)	0.826 (1.00)	0.516 (1.00)	0.643 (1.00)	0.16 (0.797)
AMPD1	7 (1%)	789	0.361 (1.00)	0.263 (0.952)	0.686 (1.00)	0.198 (0.848)	0.47 (1.00)	0.139 (0.742)	0.549 (1.00)	0.629 (1.00)	0.353 (1.00)	0.887 (1.00)	0.401 (1.00)	0.341 (1.00)	0.161 (0.8)	0.919 (1.00)
TNFSF9	5 (1%)	791			0.683 (1.00)	0.311 (0.985)	0.402 (1.00)	0.474 (1.00)	0.338 (1.00)	0.449 (1.00)
MYH11	14 (2%)	782	1 (1.00)	0.478 (1.00)	0.0755 (0.529)	0.516 (1.00)	0.809 (1.00)	0.936 (1.00)	0.0439 (0.405)	1 (1.00)	0.925 (1.00)	0.616 (1.00)	1 (1.00)	0.614 (1.00)	0.587 (1.00)	0.606 (1.00)
ANKRD36	7 (1%)	789					0.307 (0.985)	0.0905 (0.586)	0.707 (1.00)	0.515 (1.00)	0.406 (1.00)	0.309 (0.985)	0.737 (1.00)	1 (1.00)	0.895 (1.00)	0.949 (1.00)
KLKB1	7 (1%)	789					0.732 (1.00)	0.849 (1.00)	0.153 (0.78)	1 (1.00)	1 (1.00)	0.593 (1.00)	0.928 (1.00)	1 (1.00)	0.243 (0.92)	0.763 (1.00)
ST3GAL6	5 (1%)	791					0.403 (1.00)	0.296 (0.971)	0.226 (0.888)	0.0206 (0.255)	0.0592 (0.457)	0.525 (1.00)	1 (1.00)	0.0523 (0.428)	0.411 (1.00)	0.149 (0.775)
HTT	5 (1%)	791					0.199 (0.848)	0.0487 (0.42)	0.291 (0.971)	0.852 (1.00)	0.169 (0.81)	0.339 (1.00)	0.264 (0.952)	0.0231 (0.266)	0.454 (1.00)	0.714 (1.00)
ZZZ3	4 (1%)	792					1 (1.00)	0.734 (1.00)	1 (1.00)	0.683 (1.00)	0.559 (1.00)	0.0717 (0.512)	0.384 (1.00)	0.429 (1.00)	0.65 (1.00)	0.887 (1.00)
CDA	3 (0%)	793
NPTX1	5 (1%)	791					0.0357 (0.354)	0.178 (0.839)	0.779 (1.00)	0.366 (1.00)	0.274 (0.952)	0.824 (1.00)	0.0919 (0.588)	0.151 (0.778)	0.652 (1.00)	0.509 (1.00)
C10ORF46	3 (0%)	793					1 (1.00)				1 (1.00)	0.378 (1.00)
CHGB	8 (1%)	788	0.782 (1.00)	0.618 (1.00)	0.642 (1.00)	0.444 (1.00)	0.522 (1.00)	0.609 (1.00)	0.228 (0.891)	0.309 (0.985)	0.777 (1.00)	0.39 (1.00)	0.763 (1.00)	0.339 (1.00)	0.695 (1.00)	0.263 (0.952)
MTMR12	4 (1%)	792					0.187 (0.848)	0.0461 (0.412)			0.0221 (0.264)	0.103 (0.635)
CD1D	4 (1%)	792	0.878 (1.00)	1 (1.00)	0.644 (1.00)	0.125 (0.687)	0.0553 (0.44)	0.0472 (0.415)	0.777 (1.00)	0.786 (1.00)
SLC2A3	5 (1%)	791					0.399 (1.00)	0.299 (0.974)	0.0359 (0.354)	0.679 (1.00)	0.159 (0.794)	0.823 (1.00)	0.0902 (0.586)	0.0525 (0.428)	1 (1.00)	0.779 (1.00)
REXO1	8 (1%)	788			0.0526 (0.428)	0.0704 (0.511)	0.224 (0.886)	0.0232 (0.266)	0.787 (1.00)	0.208 (0.857)	0.539 (1.00)	1 (1.00)	0.913 (1.00)	0.34 (1.00)	0.696 (1.00)	0.358 (1.00)
TTC30B	7 (1%)	789					0.306 (0.984)	0.649 (1.00)	0.434 (1.00)	0.189 (0.848)	0.634 (1.00)	0.309 (0.985)	0.0759 (0.53)	0.665 (1.00)	0.452 (1.00)	0.392 (1.00)
ZMYM2	7 (1%)	789					0.308 (0.985)	0.787 (1.00)	0.626 (1.00)	1 (1.00)	0.798 (1.00)	0.503 (1.00)	0.122 (0.682)	0.21 (0.857)	0.269 (0.952)	0.366 (1.00)
ALPK3	4 (1%)	792					0.649 (1.00)	0.0462 (0.412)	0.658 (1.00)	1 (1.00)
INF2	4 (1%)	792					0.651 (1.00)	1 (1.00)	0.324 (1.00)	1 (1.00)	0.401 (1.00)	1 (1.00)	1 (1.00)	0.0527 (0.428)	1 (1.00)	0.776 (1.00)
SGOL2	8 (1%)	788	0.413 (1.00)	0.784 (1.00)	0.457 (1.00)	0.603 (1.00)	0.734 (1.00)	0.849 (1.00)	0.776 (1.00)	0.787 (1.00)	0.714 (1.00)	0.809 (1.00)	0.913 (1.00)	1 (1.00)	0.331 (1.00)	1 (1.00)
GPR132	6 (1%)	790					0.448 (1.00)	0.392 (1.00)	0.433 (1.00)	1 (1.00)	0.744 (1.00)	0.869 (1.00)	0.4 (1.00)	0.682 (1.00)	0.332 (1.00)	0.577 (1.00)
ZNF334	4 (1%)	792					0.328 (1.00)	0.885 (1.00)	0.778 (1.00)	0.628 (1.00)	1 (1.00)	0.481 (1.00)	1 (1.00)	0.197 (0.848)	0.838 (1.00)	0.578 (1.00)
RGS3	8 (1%)	788					0.739 (1.00)	0.253 (0.94)	0.464 (1.00)	0.185 (0.848)	0.8 (1.00)	0.501 (1.00)	0.217 (0.876)	0.756 (1.00)	0.293 (0.971)	0.94 (1.00)
MYH8	21 (3%)	775	0.869 (1.00)	0.729 (1.00)	0.306 (0.984)	0.0846 (0.57)	0.48 (1.00)	0.2 (0.848)	0.303 (0.983)	0.228 (0.892)	0.265 (0.952)	0.429 (1.00)	0.854 (1.00)	0.252 (0.938)	0.838 (1.00)	0.773 (1.00)
CYP11A1	7 (1%)	789	0.784 (1.00)	0.893 (1.00)	0.874 (1.00)	0.312 (0.985)	1 (1.00)	0.665 (1.00)	1 (1.00)	0.449 (1.00)	0.0414 (0.388)	0.392 (1.00)	0.913 (1.00)	0.681 (1.00)	0.839 (1.00)	0.237 (0.907)
TJAP1	3 (0%)	793					0.573 (1.00)	0.0462 (0.412)
FLNB	10 (1%)	786	0.413 (1.00)	0.347 (1.00)	0.201 (0.848)	0.604 (1.00)	0.0256 (0.285)	0.906 (1.00)	0.803 (1.00)	0.708 (1.00)	0.837 (1.00)	0.407 (1.00)	0.465 (1.00)	0.787 (1.00)	0.644 (1.00)	0.708 (1.00)
PAN3	7 (1%)	789	0.567 (1.00)	0.3 (0.976)	0.598 (1.00)	0.648 (1.00)	0.471 (1.00)		1 (1.00)	0.363 (1.00)	0.401 (1.00)	0.489 (1.00)
TTYH3	4 (1%)	792					1 (1.00)	0.721 (1.00)	0.774 (1.00)	0.787 (1.00)	0.515 (1.00)	0.633 (1.00)	0.773 (1.00)	1 (1.00)	0.651 (1.00)	1 (1.00)
SLFN11	5 (1%)	791					0.668 (1.00)	1 (1.00)	0.292 (0.971)	0.641 (1.00)	0.687 (1.00)	0.481 (1.00)	0.59 (1.00)	0.263 (0.952)	0.475 (1.00)	0.761 (1.00)
CIB1	5 (1%)	791					0.667 (1.00)	1 (1.00)	1 (1.00)	0.0506 (0.428)	0.687 (1.00)	0.314 (0.985)	0.216 (0.874)	0.0433 (0.401)	0.117 (0.669)	0.32 (0.994)
GLYAT	5 (1%)	791					0.672 (1.00)	0.922 (1.00)	0.553 (1.00)	0.679 (1.00)	0.388 (1.00)	0.4 (1.00)	0.194 (0.848)	0.265 (0.952)	0.837 (1.00)	0.698 (1.00)
AGXT2L1	4 (1%)	792					0.651 (1.00)	0.296 (0.972)			0.157 (0.794)	0.822 (1.00)	1 (1.00)	0.793 (1.00)	0.41 (1.00)	0.586 (1.00)

'IDH1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 6e-05 (Fisher's exact test), Q value = 0.002

Table S1. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
IDH1 MUTATED	1	3	0	9
IDH1 WILD-TYPE	68	40	74	45

Figure S1. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'IDH1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S2. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
IDH1 MUTATED	0	13	0	0
IDH1 WILD-TYPE	63	37	48	79

Figure S2. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 2e-05 (Fisher's exact test), Q value = 0.00079

Table S3. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
IDH1 MUTATED	0	13	1	0
IDH1 WILD-TYPE	77	80	44	60

Figure S3. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'IDH1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.00322 (Fisher's exact test), Q value = 0.069

Table S4. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
IDH1 MUTATED	13	0	1
IDH1 WILD-TYPE	125	61	75

Figure S4. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S5. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
IDH1 MUTATED	4	403	2
IDH1 WILD-TYPE	291	78	5

Figure S5. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'IDH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S6. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
IDH1 MUTATED	0	228	22	153
IDH1 WILD-TYPE	160	4	42	13

Figure S6. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'IDH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.023 (Fisher's exact test), Q value = 0.27

Table S7. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
IDH1 MUTATED	119	123	99
IDH1 WILD-TYPE	76	63	90

Figure S7. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'IDH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 0.68

Table S8. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
IDH1 MUTATED	114	129	98
IDH1 WILD-TYPE	90	90	49

'IDH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S9. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
IDH1 MUTATED	27	228	151
IDH1 WILD-TYPE	200	7	41

Figure S8. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'IDH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S10. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
IDH1 MUTATED	1	181	224
IDH1 WILD-TYPE	195	9	44

Figure S9. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S11. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IDH1 MUTATED	97	73	146	78
IDH1 WILD-TYPE	39	34	37	5

Figure S10. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S12. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IDH1 MUTATED	207	152	35
IDH1 WILD-TYPE	15	32	68

Figure S11. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S13. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IDH1 MUTATED	114	153	124
IDH1 WILD-TYPE	70	9	35

Figure S12. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'IDH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S14. Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IDH1 MUTATED	84	129	161	17
IDH1 WILD-TYPE	6	9	27	72

Figure S13. Get High-res Image Gene #1: 'IDH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00087 (Fisher's exact test), Q value = 0.023

Table S15. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TP53 MUTATED	17	19	11	22
TP53 WILD-TYPE	52	24	63	32

Figure S14. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'TP53 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 2e-05 (Fisher's exact test), Q value = 0.00079

Table S16. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TP53 MUTATED	16	30	7	16
TP53 WILD-TYPE	47	20	41	63

Figure S15. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.00085 (Fisher's exact test), Q value = 0.023

Table S17. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TP53 MUTATED	12	40	10	18
TP53 WILD-TYPE	65	53	35	42

Figure S16. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'TP53 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.202 (Fisher's exact test), Q value = 0.85

Table S18. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TP53 MUTATED	47	15	18
TP53 WILD-TYPE	91	46	58

'TP53 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S19. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TP53 MUTATED	68	255	4
TP53 WILD-TYPE	227	226	3

Figure S17. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'TP53 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S20. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TP53 MUTATED	34	221	12	8
TP53 WILD-TYPE	126	11	52	158

Figure S18. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TP53 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.276 (Fisher's exact test), Q value = 0.95

Table S21. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TP53 MUTATED	90	71	82
TP53 WILD-TYPE	105	115	107

'TP53 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00902 (Fisher's exact test), Q value = 0.15

Table S22. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TP53 MUTATED	100	95	48
TP53 WILD-TYPE	104	124	99

Figure S19. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S23. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TP53 MUTATED	71	155	67
TP53 WILD-TYPE	156	80	125

Figure S20. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S24. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TP53 MUTATED	44	176	73
TP53 WILD-TYPE	152	14	195

Figure S21. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S25. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TP53 MUTATED	82	70	74	18
TP53 WILD-TYPE	54	37	109	65

Figure S22. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'TP53 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S26. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TP53 MUTATED	133	71	40
TP53 WILD-TYPE	89	113	63

Figure S23. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0538 (Fisher's exact test), Q value = 0.43

Table S27. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TP53 MUTATED	98	79	64
TP53 WILD-TYPE	86	83	95

'TP53 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S28. Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TP53 MUTATED	79	56	85	21
TP53 WILD-TYPE	11	82	103	68

Figure S24. Get High-res Image Gene #2: 'TP53 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00215 (Fisher's exact test), Q value = 0.049

Table S29. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
ATRX MUTATED	2	4	0	7
ATRX WILD-TYPE	67	39	74	47

Figure S25. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'ATRX MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S30. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ATRX MUTATED	0	11	0	2
ATRX WILD-TYPE	63	39	48	77

Figure S26. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.00654 (Fisher's exact test), Q value = 0.12

Table S31. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
ATRX MUTATED	2	11	3	0
ATRX WILD-TYPE	75	82	42	60

Figure S27. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'ATRX MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.018 (Fisher's exact test), Q value = 0.23

Table S32. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ATRX MUTATED	13	0	3
ATRX WILD-TYPE	125	61	73

Figure S28. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S33. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ATRX MUTATED	5	204	1
ATRX WILD-TYPE	290	277	6

Figure S29. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ATRX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S34. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ATRX MUTATED	6	178	14	4
ATRX WILD-TYPE	154	54	50	162

Figure S30. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ATRX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.959 (Fisher's exact test), Q value = 1

Table S35. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ATRX MUTATED	58	58	58
ATRX WILD-TYPE	137	128	131

'ATRX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S36. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ATRX MUTATED	61	71	42
ATRX WILD-TYPE	143	148	105

'ATRX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S37. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ATRX MUTATED	25	123	55
ATRX WILD-TYPE	202	112	137

Figure S31. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ATRX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S38. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ATRX MUTATED	5	140	58
ATRX WILD-TYPE	191	50	210

Figure S32. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S39. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ATRX MUTATED	60	60	59	12
ATRX WILD-TYPE	76	47	124	71

Figure S33. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'ATRX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S40. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ATRX MUTATED	108	58	25
ATRX WILD-TYPE	114	126	78

Figure S34. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'ATRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.26 (Fisher's exact test), Q value = 0.95

Table S41. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ATRX MUTATED	76	60	52
ATRX WILD-TYPE	108	102	107

'ATRX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S42. Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ATRX MUTATED	62	43	69	14
ATRX WILD-TYPE	28	95	119	75

Figure S35. Get High-res Image Gene #3: 'ATRX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S43. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CIC MUTATED	0	109	0
CIC WILD-TYPE	295	372	7

Figure S36. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'CIC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S44. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CIC MUTATED	1	0	4	103
CIC WILD-TYPE	159	232	60	63

Figure S37. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'CIC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.271 (Fisher's exact test), Q value = 0.95

Table S45. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CIC MUTATED	37	33	25
CIC WILD-TYPE	158	153	164

'CIC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 0.95

Table S46. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CIC MUTATED	30	34	31
CIC WILD-TYPE	174	185	116

'CIC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S47. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CIC MUTATED	2	55	52
CIC WILD-TYPE	225	180	140

Figure S38. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'CIC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S48. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CIC MUTATED	0	5	104
CIC WILD-TYPE	196	185	164

Figure S39. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S49. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CIC MUTATED	15	4	43	46
CIC WILD-TYPE	121	103	140	37

Figure S40. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'CIC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S50. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CIC MUTATED	55	51	2
CIC WILD-TYPE	167	133	101

Figure S41. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'CIC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S51. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CIC MUTATED	11	61	36
CIC WILD-TYPE	173	101	123

Figure S42. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'CIC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S52. Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CIC MUTATED	2	62	43	1
CIC WILD-TYPE	88	76	145	88

Figure S43. Get High-res Image Gene #4: 'CIC MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.081 (Fisher's exact test), Q value = 0.56

Table S53. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
NF1 MUTATED	11	4	4	2
NF1 WILD-TYPE	58	39	70	52

'NF1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.00047 (Fisher's exact test), Q value = 0.013

Table S54. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
NF1 MUTATED	14	1	1	5
NF1 WILD-TYPE	49	49	47	74

Figure S44. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0244 (Fisher's exact test), Q value = 0.28

Table S55. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
NF1 MUTATED	12	3	5	8
NF1 WILD-TYPE	65	90	40	52

Figure S45. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'NF1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.931 (Fisher's exact test), Q value = 1

Table S56. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
NF1 MUTATED	14	7	7
NF1 WILD-TYPE	124	54	69

'NF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00273 (Fisher's exact test), Q value = 0.06

Table S57. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NF1 MUTATED	33	27	2
NF1 WILD-TYPE	262	454	5

Figure S46. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S58. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NF1 MUTATED	24	2	13	7
NF1 WILD-TYPE	136	230	51	159

Figure S47. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.899 (Fisher's exact test), Q value = 1

Table S59. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NF1 MUTATED	13	13	15
NF1 WILD-TYPE	182	173	174

'NF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S60. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NF1 MUTATED	27	4	10
NF1 WILD-TYPE	177	215	137

Figure S48. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 6e-05 (Fisher's exact test), Q value = 0.002

Table S61. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NF1 MUTATED	28	6	10
NF1 WILD-TYPE	199	229	182

Figure S49. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'NF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00175 (Fisher's exact test), Q value = 0.041

Table S62. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NF1 MUTATED	24	7	13
NF1 WILD-TYPE	172	183	255

Figure S50. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S63. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NF1 MUTATED	9	11	9	4
NF1 WILD-TYPE	127	96	174	79

'NF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00014 (Fisher's exact test), Q value = 0.0043

Table S64. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NF1 MUTATED	10	6	17
NF1 WILD-TYPE	212	178	86

Figure S51. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00502 (Fisher's exact test), Q value = 0.098

Table S65. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NF1 MUTATED	21	6	6
NF1 WILD-TYPE	163	156	153

Figure S52. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'NF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S66. Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NF1 MUTATED	1	6	7	19
NF1 WILD-TYPE	89	132	181	70

Figure S53. Get High-res Image Gene #5: 'NF1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'PIK3R1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.751 (Fisher's exact test), Q value = 1

Table S67. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PIK3R1 MUTATED	7	2	8	5
PIK3R1 WILD-TYPE	62	41	66	49

'PIK3R1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S68. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PIK3R1 MUTATED	7	6	6	3
PIK3R1 WILD-TYPE	56	44	42	76

'PIK3R1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 0.85

Table S69. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PIK3R1 MUTATED	12	13	4	3
PIK3R1 WILD-TYPE	65	80	41	57

'PIK3R1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.528 (Fisher's exact test), Q value = 1

Table S70. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PIK3R1 MUTATED	16	5	11
PIK3R1 WILD-TYPE	122	56	65

'PIK3R1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0171 (Fisher's exact test), Q value = 0.22

Table S71. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PIK3R1 MUTATED	26	25	2
PIK3R1 WILD-TYPE	269	456	5

Figure S54. Get High-res Image Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'PIK3R1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 5e-05 (Fisher's exact test), Q value = 0.0018

Table S72. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PIK3R1 MUTATED	21	5	1	13
PIK3R1 WILD-TYPE	139	227	63	153

Figure S55. Get High-res Image Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PIK3R1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S73. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PIK3R1 MUTATED	14	14	14
PIK3R1 WILD-TYPE	181	172	175

'PIK3R1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.918 (Fisher's exact test), Q value = 1

Table S74. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PIK3R1 MUTATED	16	15	11
PIK3R1 WILD-TYPE	188	204	136

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.248 (Fisher's exact test), Q value = 0.93

Table S75. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PIK3R1 MUTATED	15	13	6
PIK3R1 WILD-TYPE	212	222	186

'PIK3R1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.926 (Fisher's exact test), Q value = 1

Table S76. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PIK3R1 MUTATED	11	10	13
PIK3R1 WILD-TYPE	185	180	255

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0869 (Fisher's exact test), Q value = 0.58

Table S77. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PIK3R1 MUTATED	6	3	5	8
PIK3R1 WILD-TYPE	130	104	178	75

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.582 (Fisher's exact test), Q value = 1

Table S78. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PIK3R1 MUTATED	12	7	3
PIK3R1 WILD-TYPE	210	177	100

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S79. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PIK3R1 MUTATED	9	7	6
PIK3R1 WILD-TYPE	175	155	153

'PIK3R1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.63 (Fisher's exact test), Q value = 1

Table S80. Gene #6: 'PIK3R1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PIK3R1 MUTATED	3	8	9	2
PIK3R1 WILD-TYPE	87	130	179	87

'NOTCH1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S81. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NOTCH1 MUTATED	0	42	0
NOTCH1 WILD-TYPE	295	439	7

Figure S56. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NOTCH1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S82. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NOTCH1 MUTATED	1	9	0	32
NOTCH1 WILD-TYPE	159	223	64	134

Figure S57. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NOTCH1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.818 (Fisher's exact test), Q value = 1

Table S83. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NOTCH1 MUTATED	15	11	13
NOTCH1 WILD-TYPE	180	175	176

'NOTCH1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S84. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NOTCH1 MUTATED	14	15	10
NOTCH1 WILD-TYPE	190	204	137

'NOTCH1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S85. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NOTCH1 MUTATED	1	16	25
NOTCH1 WILD-TYPE	226	219	167

Figure S58. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S86. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NOTCH1 MUTATED	0	6	36
NOTCH1 WILD-TYPE	196	184	232

Figure S59. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00021 (Fisher's exact test), Q value = 0.0062

Table S87. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NOTCH1 MUTATED	4	3	21	13
NOTCH1 WILD-TYPE	132	104	162	70

Figure S60. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00404 (Fisher's exact test), Q value = 0.082

Table S88. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NOTCH1 MUTATED	16	23	2
NOTCH1 WILD-TYPE	206	161	101

Figure S61. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00161 (Fisher's exact test), Q value = 0.039

Table S89. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NOTCH1 MUTATED	6	13	22
NOTCH1 WILD-TYPE	178	149	137

Figure S62. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'NOTCH1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00012 (Fisher's exact test), Q value = 0.0037

Table S90. Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NOTCH1 MUTATED	3	14	24	0
NOTCH1 WILD-TYPE	87	124	164	89

Figure S63. Get High-res Image Gene #7: 'NOTCH1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00037 (Fisher's exact test), Q value = 0.011

Table S91. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
IDH2 MUTATED	0	20	0
IDH2 WILD-TYPE	295	461	7

Figure S64. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'IDH2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 7e-05 (Fisher's exact test), Q value = 0.0023

Table S92. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
IDH2 MUTATED	0	3	4	13
IDH2 WILD-TYPE	160	229	60	153

Figure S65. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'IDH2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S93. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
IDH2 MUTATED	5	8	4
IDH2 WILD-TYPE	190	178	185

'IDH2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.133 (Fisher's exact test), Q value = 0.72

Table S94. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
IDH2 MUTATED	7	3	7
IDH2 WILD-TYPE	197	216	140

'IDH2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S95. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
IDH2 MUTATED	0	6	14
IDH2 WILD-TYPE	227	229	178

Figure S66. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'IDH2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S96. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
IDH2 MUTATED	0	1	19
IDH2 WILD-TYPE	196	189	249

Figure S67. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00917 (Fisher's exact test), Q value = 0.15

Table S97. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IDH2 MUTATED	3	0	12	5
IDH2 WILD-TYPE	133	107	171	78

Figure S68. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 7e-04 (Fisher's exact test), Q value = 0.019

Table S98. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IDH2 MUTATED	5	15	0
IDH2 WILD-TYPE	217	169	103

Figure S69. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00305 (Fisher's exact test), Q value = 0.066

Table S99. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IDH2 MUTATED	1	8	11
IDH2 WILD-TYPE	183	154	148

Figure S70. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'IDH2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0468 (Fisher's exact test), Q value = 0.41

Table S100. Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IDH2 MUTATED	2	6	12	0
IDH2 WILD-TYPE	88	132	176	89

Figure S71. Get High-res Image Gene #8: 'IDH2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S101. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
FUBP1 MUTATED	0	47	0
FUBP1 WILD-TYPE	295	434	7

Figure S72. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FUBP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S102. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
FUBP1 MUTATED	1	0	0	46
FUBP1 WILD-TYPE	159	232	64	120

Figure S73. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'FUBP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S103. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
FUBP1 MUTATED	15	16	10
FUBP1 WILD-TYPE	180	170	179

'FUBP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S104. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
FUBP1 MUTATED	11	17	13
FUBP1 WILD-TYPE	193	202	134

'FUBP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S105. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
FUBP1 MUTATED	1	21	25
FUBP1 WILD-TYPE	226	214	167

Figure S74. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'FUBP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S106. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
FUBP1 MUTATED	0	3	44
FUBP1 WILD-TYPE	196	187	224

Figure S75. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 2e-05 (Fisher's exact test), Q value = 0.00079

Table S107. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FUBP1 MUTATED	6	1	22	18
FUBP1 WILD-TYPE	130	106	161	65

Figure S76. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 9e-04 (Fisher's exact test), Q value = 0.023

Table S108. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FUBP1 MUTATED	24	22	1
FUBP1 WILD-TYPE	198	162	102

Figure S77. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00767 (Fisher's exact test), Q value = 0.13

Table S109. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FUBP1 MUTATED	8	22	17
FUBP1 WILD-TYPE	176	140	142

Figure S78. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'FUBP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S110. Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FUBP1 MUTATED	0	23	24	0
FUBP1 WILD-TYPE	90	115	164	89

Figure S79. Get High-res Image Gene #9: 'FUBP1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0337 (Fisher's exact test), Q value = 0.34

Table S111. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
RB1 MUTATED	11	2	3	2
RB1 WILD-TYPE	58	41	71	52

Figure S80. Get High-res Image Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'RB1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0173 (Fisher's exact test), Q value = 0.23

Table S112. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
RB1 MUTATED	5	2	0	11
RB1 WILD-TYPE	58	48	48	68

Figure S81. Get High-res Image Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.132 (Fisher's exact test), Q value = 0.72

Table S113. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
RB1 MUTATED	11	4	3	6
RB1 WILD-TYPE	66	89	42	54

'RB1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S114. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
RB1 MUTATED	12	6	6
RB1 WILD-TYPE	126	55	70

'RB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S115. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
RB1 MUTATED	27	2	1
RB1 WILD-TYPE	268	479	6

Figure S82. Get High-res Image Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'RB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S116. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
RB1 MUTATED	12	0	1	1
RB1 WILD-TYPE	148	232	63	165

Figure S83. Get High-res Image Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'RB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.91

Table S117. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
RB1 MUTATED	6	2	7
RB1 WILD-TYPE	189	184	182

'RB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.176 (Fisher's exact test), Q value = 0.83

Table S118. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
RB1 MUTATED	9	4	2
RB1 WILD-TYPE	195	215	145

'RB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 8e-05 (Fisher's exact test), Q value = 0.0026

Table S119. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
RB1 MUTATED	14	1	1
RB1 WILD-TYPE	213	234	191

Figure S84. Get High-res Image Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'RB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 6e-05 (Fisher's exact test), Q value = 0.002

Table S120. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
RB1 MUTATED	13	1	2
RB1 WILD-TYPE	183	189	266

Figure S85. Get High-res Image Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S121. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RB1 MUTATED	3	1	1	1
RB1 WILD-TYPE	133	106	182	82

'RB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0324 (Fisher's exact test), Q value = 0.33

Table S122. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RB1 MUTATED	1	1	4
RB1 WILD-TYPE	221	183	99

Figure S86. Get High-res Image Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S123. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RB1 MUTATED	3	1	2
RB1 WILD-TYPE	181	161	157

'RB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.246 (Fisher's exact test), Q value = 0.93

Table S124. Gene #10: 'RB1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RB1 MUTATED	0	1	2	3
RB1 WILD-TYPE	90	137	186	86

'TCF12 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S125. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TCF12 MUTATED	1	0	1	1
TCF12 WILD-TYPE	68	43	73	53

'TCF12 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S126. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TCF12 MUTATED	1	1	1	0
TCF12 WILD-TYPE	62	49	47	79

'TCF12 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S127. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TCF12 MUTATED	2	2	0	0
TCF12 WILD-TYPE	75	91	45	60

'TCF12 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.257 (Fisher's exact test), Q value = 0.95

Table S128. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TCF12 MUTATED	2	2	0
TCF12 WILD-TYPE	136	59	76

'TCF12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.221 (Fisher's exact test), Q value = 0.88

Table S129. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TCF12 MUTATED	3	15	0
TCF12 WILD-TYPE	292	466	7

'TCF12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S130. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TCF12 MUTATED	3	7	1	6
TCF12 WILD-TYPE	157	225	63	160

'TCF12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.738 (Fisher's exact test), Q value = 1

Table S131. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TCF12 MUTATED	7	4	5
TCF12 WILD-TYPE	188	182	184

'TCF12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S132. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TCF12 MUTATED	8	6	2
TCF12 WILD-TYPE	196	213	145

'TCF12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.13 (Fisher's exact test), Q value = 0.71

Table S133. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TCF12 MUTATED	2	9	5
TCF12 WILD-TYPE	225	226	187

'TCF12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.97

Table S134. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TCF12 MUTATED	2	6	8
TCF12 WILD-TYPE	194	184	260

'TCF12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S135. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TCF12 MUTATED	4	2	5	4
TCF12 WILD-TYPE	132	105	178	79

'TCF12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.517 (Fisher's exact test), Q value = 1

Table S136. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TCF12 MUTATED	8	6	1
TCF12 WILD-TYPE	214	178	102

'TCF12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S137. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TCF12 MUTATED	5	5	5
TCF12 WILD-TYPE	179	157	154

'TCF12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.514 (Fisher's exact test), Q value = 1

Table S138. Gene #11: 'TCF12 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TCF12 MUTATED	4	3	7	1
TCF12 WILD-TYPE	86	135	181	88

'PIK3CA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.953 (Fisher's exact test), Q value = 1

Table S139. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PIK3CA MUTATED	6	5	8	5
PIK3CA WILD-TYPE	63	38	66	49

'PIK3CA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.97

Table S140. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PIK3CA MUTATED	8	6	6	4
PIK3CA WILD-TYPE	55	44	42	75

'PIK3CA MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 0.97

Table S141. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PIK3CA MUTATED	9	10	1	6
PIK3CA WILD-TYPE	68	83	44	54

'PIK3CA MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S142. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PIK3CA MUTATED	12	6	8
PIK3CA WILD-TYPE	126	55	68

'PIK3CA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S143. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PIK3CA MUTATED	26	42	1
PIK3CA WILD-TYPE	269	439	6

'PIK3CA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S144. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PIK3CA MUTATED	21	6	3	27
PIK3CA WILD-TYPE	139	226	61	139

Figure S87. Get High-res Image Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PIK3CA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.372 (Fisher's exact test), Q value = 1

Table S145. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PIK3CA MUTATED	13	20	17
PIK3CA WILD-TYPE	182	166	172

'PIK3CA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S146. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PIK3CA MUTATED	19	15	16
PIK3CA WILD-TYPE	185	204	131

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.425 (Fisher's exact test), Q value = 1

Table S147. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PIK3CA MUTATED	23	16	15
PIK3CA WILD-TYPE	204	219	177

'PIK3CA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0368 (Fisher's exact test), Q value = 0.36

Table S148. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PIK3CA MUTATED	18	8	28
PIK3CA WILD-TYPE	178	182	240

Figure S88. Get High-res Image Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00952 (Fisher's exact test), Q value = 0.15

Table S149. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PIK3CA MUTATED	5	14	13	12
PIK3CA WILD-TYPE	131	93	170	71

Figure S89. Get High-res Image Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.039 (Fisher's exact test), Q value = 0.37

Table S150. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PIK3CA MUTATED	13	16	15
PIK3CA WILD-TYPE	209	168	88

Figure S90. Get High-res Image Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S151. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PIK3CA MUTATED	17	10	17
PIK3CA WILD-TYPE	167	152	142

'PIK3CA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00087 (Fisher's exact test), Q value = 0.023

Table S152. Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PIK3CA MUTATED	0	15	17	12
PIK3CA WILD-TYPE	90	123	171	77

Figure S91. Get High-res Image Gene #12: 'PIK3CA MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'STK19 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S153. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
STK19 MUTATED	3	8	0
STK19 WILD-TYPE	292	473	7

'STK19 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S154. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
STK19 MUTATED	3	4	2	1
STK19 WILD-TYPE	157	228	62	165

'STK19 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.67

Table S155. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
STK19 MUTATED	3	4	0
STK19 WILD-TYPE	192	182	189

'STK19 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S156. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
STK19 MUTATED	2	2	3
STK19 WILD-TYPE	202	217	144

'STK19 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S157. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
STK19 MUTATED	4	2	5
STK19 WILD-TYPE	223	233	187

'STK19 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.864 (Fisher's exact test), Q value = 1

Table S158. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
STK19 MUTATED	3	4	4
STK19 WILD-TYPE	193	186	264

'STK19 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.167 (Fisher's exact test), Q value = 0.81

Table S159. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
STK19 MUTATED	1	4	5	0
STK19 WILD-TYPE	135	103	178	83

'STK19 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S160. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
STK19 MUTATED	3	4	3
STK19 WILD-TYPE	219	180	100

'STK19 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S161. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
STK19 MUTATED	3	4	3
STK19 WILD-TYPE	181	158	156

'STK19 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S162. Gene #13: 'STK19 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
STK19 MUTATED	1	2	5	2
STK19 WILD-TYPE	89	136	183	87

'PTEN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.67

Table S163. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PTEN MUTATED	25	10	18	22
PTEN WILD-TYPE	44	33	56	32

'PTEN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0739 (Fisher's exact test), Q value = 0.52

Table S164. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PTEN MUTATED	18	16	9	32
PTEN WILD-TYPE	45	34	39	47

'PTEN MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0274 (Fisher's exact test), Q value = 0.29

Table S165. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PTEN MUTATED	30	19	18	20
PTEN WILD-TYPE	47	74	27	40

Figure S92. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'PTEN MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S166. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PTEN MUTATED	45	21	21
PTEN WILD-TYPE	93	40	55

'PTEN MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S167. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PTEN MUTATED	91	16	2
PTEN WILD-TYPE	204	465	5

Figure S93. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'PTEN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S168. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PTEN MUTATED	47	3	6	1
PTEN WILD-TYPE	113	229	58	165

Figure S94. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PTEN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.85

Table S169. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PTEN MUTATED	19	15	26
PTEN WILD-TYPE	176	171	163

'PTEN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.67

Table S170. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PTEN MUTATED	29	19	12
PTEN WILD-TYPE	175	200	135

'PTEN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S171. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PTEN MUTATED	62	4	3
PTEN WILD-TYPE	165	231	189

Figure S95. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S172. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PTEN MUTATED	61	4	4
PTEN WILD-TYPE	135	186	264

Figure S96. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00376 (Fisher's exact test), Q value = 0.078

Table S173. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PTEN MUTATED	12	8	3	1
PTEN WILD-TYPE	124	99	180	82

Figure S97. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S174. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PTEN MUTATED	6	1	17
PTEN WILD-TYPE	216	183	86

Figure S98. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S175. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PTEN MUTATED	20	2	2
PTEN WILD-TYPE	164	160	157

Figure S99. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'PTEN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S176. Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PTEN MUTATED	3	3	1	17
PTEN WILD-TYPE	87	135	187	72

Figure S100. Get High-res Image Gene #14: 'PTEN MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0204 (Fisher's exact test), Q value = 0.25

Table S177. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ARID1A MUTATED	2	19	0
ARID1A WILD-TYPE	293	462	7

Figure S101. Get High-res Image Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ARID1A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.022 (Fisher's exact test), Q value = 0.26

Table S178. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ARID1A MUTATED	2	6	1	12
ARID1A WILD-TYPE	158	226	63	154

Figure S102. Get High-res Image Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ARID1A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S179. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ARID1A MUTATED	9	7	4
ARID1A WILD-TYPE	186	179	185

'ARID1A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S180. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ARID1A MUTATED	7	8	5
ARID1A WILD-TYPE	197	211	142

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0255 (Fisher's exact test), Q value = 0.28

Table S181. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ARID1A MUTATED	2	12	7
ARID1A WILD-TYPE	225	223	185

Figure S103. Get High-res Image Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ARID1A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00531 (Fisher's exact test), Q value = 0.1

Table S182. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ARID1A MUTATED	1	5	15
ARID1A WILD-TYPE	195	185	253

Figure S104. Get High-res Image Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.99

Table S183. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ARID1A MUTATED	5	2	7	6
ARID1A WILD-TYPE	131	105	176	77

'ARID1A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S184. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ARID1A MUTATED	10	8	2
ARID1A WILD-TYPE	212	176	101

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0827 (Fisher's exact test), Q value = 0.56

Table S185. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ARID1A MUTATED	3	10	7
ARID1A WILD-TYPE	181	152	152

'ARID1A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0295 (Fisher's exact test), Q value = 0.31

Table S186. Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ARID1A MUTATED	1	11	7	1
ARID1A WILD-TYPE	89	127	181	88

Figure S105. Get High-res Image Gene #15: 'ARID1A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'SLC26A3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.941 (Fisher's exact test), Q value = 1

Table S187. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
SLC26A3 MUTATED	1	1	2	2
SLC26A3 WILD-TYPE	68	42	72	52

'SLC26A3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S188. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SLC26A3 MUTATED	2	1	2	1
SLC26A3 WILD-TYPE	61	49	46	78

'SLC26A3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S189. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
SLC26A3 MUTATED	1	4	0	2
SLC26A3 WILD-TYPE	76	89	45	58

'SLC26A3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S190. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SLC26A3 MUTATED	4	0	3
SLC26A3 WILD-TYPE	134	61	73

'SLC26A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0111 (Fisher's exact test), Q value = 0.17

Table S191. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SLC26A3 MUTATED	9	2	0
SLC26A3 WILD-TYPE	286	479	7

Figure S106. Get High-res Image Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'SLC26A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0221 (Fisher's exact test), Q value = 0.26

Table S192. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SLC26A3 MUTATED	5	1	0	0
SLC26A3 WILD-TYPE	155	231	64	166

Figure S107. Get High-res Image Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SLC26A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0988 (Fisher's exact test), Q value = 0.62

Table S193. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SLC26A3 MUTATED	5	0	3
SLC26A3 WILD-TYPE	190	186	186

'SLC26A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0647 (Fisher's exact test), Q value = 0.48

Table S194. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SLC26A3 MUTATED	6	2	0
SLC26A3 WILD-TYPE	198	217	147

'SLC26A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00459 (Fisher's exact test), Q value = 0.091

Table S195. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SLC26A3 MUTATED	7	1	0
SLC26A3 WILD-TYPE	220	234	192

Figure S108. Get High-res Image Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'SLC26A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00617 (Fisher's exact test), Q value = 0.11

Table S196. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SLC26A3 MUTATED	6	2	0
SLC26A3 WILD-TYPE	190	188	268

Figure S109. Get High-res Image Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0458 (Fisher's exact test), Q value = 0.41

Table S197. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC26A3 MUTATED	1	3	0	0
SLC26A3 WILD-TYPE	135	104	183	83

Figure S110. Get High-res Image Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0278 (Fisher's exact test), Q value = 0.3

Table S198. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC26A3 MUTATED	1	0	3
SLC26A3 WILD-TYPE	221	184	100

Figure S111. Get High-res Image Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S199. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC26A3 MUTATED	2	1	1
SLC26A3 WILD-TYPE	182	161	158

'SLC26A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.85

Table S200. Gene #16: 'SLC26A3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC26A3 MUTATED	1	0	1	2
SLC26A3 WILD-TYPE	89	138	187	87

'NIPBL MUTATION STATUS' versus 'CN_CNMF'

P value = 0.028 (Fisher's exact test), Q value = 0.3

Table S201. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NIPBL MUTATED	2	18	0
NIPBL WILD-TYPE	293	463	7

Figure S112. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NIPBL MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00021 (Fisher's exact test), Q value = 0.0062

Table S202. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NIPBL MUTATED	3	2	0	14
NIPBL WILD-TYPE	157	230	64	152

Figure S113. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NIPBL MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 0.9

Table S203. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NIPBL MUTATED	6	2	7
NIPBL WILD-TYPE	189	184	182

'NIPBL MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S204. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NIPBL MUTATED	6	7	2
NIPBL WILD-TYPE	198	212	145

'NIPBL MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0527 (Fisher's exact test), Q value = 0.43

Table S205. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NIPBL MUTATED	3	12	4
NIPBL WILD-TYPE	224	223	188

'NIPBL MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0481 (Fisher's exact test), Q value = 0.42

Table S206. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NIPBL MUTATED	2	4	13
NIPBL WILD-TYPE	194	186	255

Figure S114. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NIPBL MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S207. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NIPBL MUTATED	5	4	4	5
NIPBL WILD-TYPE	131	103	179	78

'NIPBL MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.172 (Fisher's exact test), Q value = 0.82

Table S208. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NIPBL MUTATED	12	4	2
NIPBL WILD-TYPE	210	180	101

'NIPBL MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0116 (Fisher's exact test), Q value = 0.18

Table S209. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NIPBL MUTATED	3	12	3
NIPBL WILD-TYPE	181	150	156

Figure S115. Get High-res Image Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'NIPBL MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0592 (Fisher's exact test), Q value = 0.46

Table S210. Gene #17: 'NIPBL MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NIPBL MUTATED	3	10	4	1
NIPBL WILD-TYPE	87	128	184	88

'ZMIZ1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S211. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
ZMIZ1 MUTATED	2	1	0	1
ZMIZ1 WILD-TYPE	67	42	74	53

'ZMIZ1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S212. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ZMIZ1 MUTATED	1	1	0	2
ZMIZ1 WILD-TYPE	62	49	48	77

'ZMIZ1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S213. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
ZMIZ1 MUTATED	2	2	0	0
ZMIZ1 WILD-TYPE	75	91	45	60

'ZMIZ1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S214. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ZMIZ1 MUTATED	1	1	2
ZMIZ1 WILD-TYPE	137	60	74

'ZMIZ1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.236 (Fisher's exact test), Q value = 0.91

Table S215. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZMIZ1 MUTATED	2	10	0
ZMIZ1 WILD-TYPE	293	471	7

'ZMIZ1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S216. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZMIZ1 MUTATED	2	2	0	5
ZMIZ1 WILD-TYPE	158	230	64	161

'ZMIZ1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0647 (Fisher's exact test), Q value = 0.48

Table S217. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZMIZ1 MUTATED	3	7	1
ZMIZ1 WILD-TYPE	192	179	188

'ZMIZ1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.118 (Fisher's exact test), Q value = 0.67

Table S218. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZMIZ1 MUTATED	3	2	6
ZMIZ1 WILD-TYPE	201	217	141

'ZMIZ1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S219. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZMIZ1 MUTATED	3	5	3
ZMIZ1 WILD-TYPE	224	230	189

'ZMIZ1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S220. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZMIZ1 MUTATED	1	4	6
ZMIZ1 WILD-TYPE	195	186	262

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.478 (Fisher's exact test), Q value = 1

Table S221. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZMIZ1 MUTATED	1	2	3	3
ZMIZ1 WILD-TYPE	135	105	180	80

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S222. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZMIZ1 MUTATED	5	2	2
ZMIZ1 WILD-TYPE	217	182	101

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0187 (Fisher's exact test), Q value = 0.24

Table S223. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZMIZ1 MUTATED	0	6	3
ZMIZ1 WILD-TYPE	184	156	156

Figure S116. Get High-res Image Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'ZMIZ1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.419 (Fisher's exact test), Q value = 1

Table S224. Gene #18: 'ZMIZ1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZMIZ1 MUTATED	0	4	4	1
ZMIZ1 WILD-TYPE	90	134	184	88

'NUDT11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0165 (Fisher's exact test), Q value = 0.22

Table S225. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NUDT11 MUTATED	0	11	0
NUDT11 WILD-TYPE	295	470	7

Figure S117. Get High-res Image Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NUDT11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S226. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NUDT11 MUTATED	1	6	0	4
NUDT11 WILD-TYPE	159	226	64	162

'NUDT11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S227. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NUDT11 MUTATED	5	2	4
NUDT11 WILD-TYPE	190	184	185

'NUDT11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.97

Table S228. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NUDT11 MUTATED	6	2	3
NUDT11 WILD-TYPE	198	217	144

'NUDT11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S229. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NUDT11 MUTATED	2	6	3
NUDT11 WILD-TYPE	225	229	189

'NUDT11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.015 (Fisher's exact test), Q value = 0.21

Table S230. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NUDT11 MUTATED	0	7	4
NUDT11 WILD-TYPE	196	183	264

Figure S118. Get High-res Image Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0261 (Fisher's exact test), Q value = 0.29

Table S231. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NUDT11 MUTATED	1	4	1	4
NUDT11 WILD-TYPE	135	103	182	79

Figure S119. Get High-res Image Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.918 (Fisher's exact test), Q value = 1

Table S232. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NUDT11 MUTATED	5	3	2
NUDT11 WILD-TYPE	217	181	101

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 0.81

Table S233. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NUDT11 MUTATED	1	5	4
NUDT11 WILD-TYPE	183	157	155

'NUDT11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.295 (Fisher's exact test), Q value = 0.97

Table S234. Gene #19: 'NUDT11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NUDT11 MUTATED	1	5	4	0
NUDT11 WILD-TYPE	89	133	184	89

'GAGE2A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S235. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
GAGE2A MUTATED	1	7	0
GAGE2A WILD-TYPE	294	474	7

'GAGE2A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S236. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
GAGE2A MUTATED	1	4	0	3
GAGE2A WILD-TYPE	159	228	64	163

'GAGE2A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S237. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
GAGE2A MUTATED	2	3	3
GAGE2A WILD-TYPE	193	183	186

'GAGE2A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.288 (Fisher's exact test), Q value = 0.97

Table S238. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
GAGE2A MUTATED	4	1	3
GAGE2A WILD-TYPE	200	218	144

'GAGE2A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.905 (Fisher's exact test), Q value = 1

Table S239. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
GAGE2A MUTATED	2	3	3
GAGE2A WILD-TYPE	225	232	189

'GAGE2A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S240. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
GAGE2A MUTATED	1	3	4
GAGE2A WILD-TYPE	195	187	264

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.656 (Fisher's exact test), Q value = 1

Table S241. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GAGE2A MUTATED	1	3	3	1
GAGE2A WILD-TYPE	135	104	180	82

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.903 (Fisher's exact test), Q value = 1

Table S242. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GAGE2A MUTATED	3	3	2
GAGE2A WILD-TYPE	219	181	101

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S243. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GAGE2A MUTATED	2	3	3
GAGE2A WILD-TYPE	182	159	156

'GAGE2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.923 (Fisher's exact test), Q value = 1

Table S244. Gene #20: 'GAGE2A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GAGE2A MUTATED	2	2	3	1
GAGE2A WILD-TYPE	88	136	185	88

'CREBZF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0371 (Fisher's exact test), Q value = 0.36

Table S245. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CREBZF MUTATED	0	9	0
CREBZF WILD-TYPE	295	472	7

Figure S120. Get High-res Image Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'CREBZF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 6e-04 (Fisher's exact test), Q value = 0.017

Table S246. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CREBZF MUTATED	0	0	0	7
CREBZF WILD-TYPE	160	232	64	159

Figure S121. Get High-res Image Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'CREBZF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S247. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CREBZF MUTATED	1	4	3
CREBZF WILD-TYPE	194	182	186

'CREBZF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S248. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CREBZF MUTATED	1	4	3
CREBZF WILD-TYPE	203	215	144

'CREBZF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0213 (Fisher's exact test), Q value = 0.26

Table S249. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CREBZF MUTATED	1	1	6
CREBZF WILD-TYPE	226	234	186

Figure S122. Get High-res Image Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'CREBZF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0687 (Fisher's exact test), Q value = 0.5

Table S250. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CREBZF MUTATED	0	2	6
CREBZF WILD-TYPE	196	188	262

'CREBZF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.85

Table S251. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CREBZF MUTATED	0	1	5	1
CREBZF WILD-TYPE	136	106	178	82

'CREBZF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0139 (Fisher's exact test), Q value = 0.19

Table S252. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CREBZF MUTATED	0	6	1
CREBZF WILD-TYPE	222	178	102

Figure S123. Get High-res Image Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'CREBZF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 0.67

Table S253. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CREBZF MUTATED	1	1	5
CREBZF WILD-TYPE	183	161	154

'CREBZF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0532 (Fisher's exact test), Q value = 0.43

Table S254. Gene #21: 'CREBZF MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CREBZF MUTATED	0	0	6	1
CREBZF WILD-TYPE	90	138	182	88

'PLCG1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S255. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PLCG1 MUTATED	2	0	1	2
PLCG1 WILD-TYPE	67	43	73	52

'PLCG1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S256. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PLCG1 MUTATED	2	1	1	1
PLCG1 WILD-TYPE	61	49	47	78

'PLCG1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S257. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PLCG1 MUTATED	2	1	1	1
PLCG1 WILD-TYPE	75	92	44	59

'PLCG1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S258. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PLCG1 MUTATED	2	1	2
PLCG1 WILD-TYPE	136	60	74

'PLCG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0114 (Fisher's exact test), Q value = 0.18

Table S259. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PLCG1 MUTATED	9	2	0
PLCG1 WILD-TYPE	286	479	7

Figure S124. Get High-res Image Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'PLCG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.86

Table S260. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PLCG1 MUTATED	4	1	1	1
PLCG1 WILD-TYPE	156	231	63	165

'PLCG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S261. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PLCG1 MUTATED	1	1	3
PLCG1 WILD-TYPE	194	185	186

'PLCG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S262. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PLCG1 MUTATED	2	2	1
PLCG1 WILD-TYPE	202	217	146

'PLCG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S263. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PLCG1 MUTATED	4	2	1
PLCG1 WILD-TYPE	223	233	191

'PLCG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.269 (Fisher's exact test), Q value = 0.95

Table S264. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PLCG1 MUTATED	4	2	1
PLCG1 WILD-TYPE	192	188	267

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0263 (Fisher's exact test), Q value = 0.29

Table S265. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PLCG1 MUTATED	5	0	1	0
PLCG1 WILD-TYPE	131	107	182	83

Figure S125. Get High-res Image Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0655 (Fisher's exact test), Q value = 0.49

Table S266. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PLCG1 MUTATED	3	0	3
PLCG1 WILD-TYPE	219	184	100

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0545 (Fisher's exact test), Q value = 0.44

Table S267. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PLCG1 MUTATED	5	1	0
PLCG1 WILD-TYPE	179	161	159

'PLCG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 0.78

Table S268. Gene #22: 'PLCG1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PLCG1 MUTATED	0	2	1	3
PLCG1 WILD-TYPE	90	136	187	86

'STAG2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.391 (Fisher's exact test), Q value = 1

Table S269. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
STAG2 MUTATED	4	3	1	2
STAG2 WILD-TYPE	65	40	73	52

'STAG2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S270. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
STAG2 MUTATED	2	1	3	4
STAG2 WILD-TYPE	61	49	45	75

'STAG2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.715 (Fisher's exact test), Q value = 1

Table S271. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
STAG2 MUTATED	4	5	2	1
STAG2 WILD-TYPE	73	88	43	59

'STAG2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S272. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
STAG2 MUTATED	5	2	5
STAG2 WILD-TYPE	133	59	71

'STAG2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-04 (Fisher's exact test), Q value = 0.0031

Table S273. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
STAG2 MUTATED	13	2	1
STAG2 WILD-TYPE	282	479	6

Figure S126. Get High-res Image Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'STAG2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00066 (Fisher's exact test), Q value = 0.018

Table S274. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
STAG2 MUTATED	8	1	0	0
STAG2 WILD-TYPE	152	231	64	166

Figure S127. Get High-res Image Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'STAG2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S275. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
STAG2 MUTATED	3	4	3
STAG2 WILD-TYPE	192	182	186

'STAG2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0592 (Fisher's exact test), Q value = 0.46

Table S276. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
STAG2 MUTATED	7	1	2
STAG2 WILD-TYPE	197	218	145

'STAG2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 9e-05 (Fisher's exact test), Q value = 0.0028

Table S277. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
STAG2 MUTATED	10	0	1
STAG2 WILD-TYPE	217	235	191

Figure S128. Get High-res Image Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'STAG2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00113 (Fisher's exact test), Q value = 0.028

Table S278. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
STAG2 MUTATED	9	1	1
STAG2 WILD-TYPE	187	189	267

Figure S129. Get High-res Image Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'STAG2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S279. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
STAG2 MUTATED	1	2	1	0
STAG2 WILD-TYPE	135	105	182	83

'STAG2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0139 (Fisher's exact test), Q value = 0.19

Table S280. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
STAG2 MUTATED	0	1	3
STAG2 WILD-TYPE	222	183	100

Figure S130. Get High-res Image Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S281. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
STAG2 MUTATED	2	0	2
STAG2 WILD-TYPE	182	162	157

'STAG2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.237 (Fisher's exact test), Q value = 0.91

Table S282. Gene #23: 'STAG2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
STAG2 MUTATED	0	0	2	2
STAG2 WILD-TYPE	90	138	186	87

'SEMG1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S283. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
SEMG1 MUTATED	1	1	4	2
SEMG1 WILD-TYPE	68	42	70	52

'SEMG1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.176 (Fisher's exact test), Q value = 0.83

Table S284. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SEMG1 MUTATED	0	2	1	5
SEMG1 WILD-TYPE	63	48	47	74

'SEMG1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S285. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
SEMG1 MUTATED	2	4	1	1
SEMG1 WILD-TYPE	75	89	44	59

'SEMG1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S286. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SEMG1 MUTATED	4	2	2
SEMG1 WILD-TYPE	134	59	74

'SEMG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00099 (Fisher's exact test), Q value = 0.025

Table S287. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SEMG1 MUTATED	10	1	0
SEMG1 WILD-TYPE	285	480	7

Figure S131. Get High-res Image Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'SEMG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0129 (Fisher's exact test), Q value = 0.19

Table S288. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SEMG1 MUTATED	4	0	0	0
SEMG1 WILD-TYPE	156	232	64	166

Figure S132. Get High-res Image Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SEMG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S289. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SEMG1 MUTATED	1	0	2
SEMG1 WILD-TYPE	194	186	187

'SEMG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S290. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SEMG1 MUTATED	1	2	0
SEMG1 WILD-TYPE	203	217	147

'SEMG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0023 (Fisher's exact test), Q value = 0.052

Table S291. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SEMG1 MUTATED	6	0	0
SEMG1 WILD-TYPE	221	235	192

Figure S133. Get High-res Image Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'SEMG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00916 (Fisher's exact test), Q value = 0.15

Table S292. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SEMG1 MUTATED	5	1	0
SEMG1 WILD-TYPE	191	189	268

Figure S134. Get High-res Image Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.19 (Fisher's exact test), Q value = 0.85

Table S293. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SEMG1 MUTATED	1	2	0	0
SEMG1 WILD-TYPE	135	105	183	83

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.78

Table S294. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SEMG1 MUTATED	1	0	2
SEMG1 WILD-TYPE	221	184	101

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S295. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SEMG1 MUTATED	2	0	1
SEMG1 WILD-TYPE	182	162	158

'SEMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S296. Gene #24: 'SEMG1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SEMG1 MUTATED	1	0	1	1
SEMG1 WILD-TYPE	89	138	187	88

'ZNF709 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S297. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZNF709 MUTATED	2	4	0
ZNF709 WILD-TYPE	293	477	7

'ZNF709 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S298. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZNF709 MUTATED	1	2	0	2
ZNF709 WILD-TYPE	159	230	64	164

'ZNF709 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S299. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZNF709 MUTATED	2	2	1
ZNF709 WILD-TYPE	193	184	188

'ZNF709 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S300. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZNF709 MUTATED	2	1	2
ZNF709 WILD-TYPE	202	218	145

'ZNF709 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.86 (Fisher's exact test), Q value = 1

Table S301. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZNF709 MUTATED	1	2	2
ZNF709 WILD-TYPE	226	233	190

'ZNF709 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S302. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZNF709 MUTATED	1	2	2
ZNF709 WILD-TYPE	195	188	266

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S303. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF709 MUTATED	1	1	2	0
ZNF709 WILD-TYPE	135	106	181	83

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S304. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF709 MUTATED	1	2	1
ZNF709 WILD-TYPE	221	182	102

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.273 (Fisher's exact test), Q value = 0.95

Table S305. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF709 MUTATED	3	0	1
ZNF709 WILD-TYPE	181	162	158

'ZNF709 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S306. Gene #25: 'ZNF709 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF709 MUTATED	1	1	2	0
ZNF709 WILD-TYPE	89	137	186	89

'MUC17 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0128 (Fisher's exact test), Q value = 0.19

Table S307. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
MUC17 MUTATED	10	5	1	3
MUC17 WILD-TYPE	59	38	73	51

Figure S135. Get High-res Image Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'MUC17 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S308. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MUC17 MUTATED	8	1	3	7
MUC17 WILD-TYPE	55	49	45	72

'MUC17 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S309. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
MUC17 MUTATED	5	7	3	7
MUC17 WILD-TYPE	72	86	42	53

'MUC17 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.704 (Fisher's exact test), Q value = 1

Table S310. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MUC17 MUTATED	10	4	8
MUC17 WILD-TYPE	128	57	68

'MUC17 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.79

Table S311. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MUC17 MUTATED	23	25	1
MUC17 WILD-TYPE	272	456	6

'MUC17 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S312. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MUC17 MUTATED	14	12	4	7
MUC17 WILD-TYPE	146	220	60	159

'MUC17 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S313. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MUC17 MUTATED	15	10	8
MUC17 WILD-TYPE	180	176	181

'MUC17 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.258 (Fisher's exact test), Q value = 0.95

Table S314. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MUC17 MUTATED	16	9	8
MUC17 WILD-TYPE	188	210	139

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0131 (Fisher's exact test), Q value = 0.19

Table S315. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MUC17 MUTATED	19	6	14
MUC17 WILD-TYPE	208	229	178

Figure S136. Get High-res Image Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'MUC17 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.209 (Fisher's exact test), Q value = 0.86

Table S316. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MUC17 MUTATED	15	13	11
MUC17 WILD-TYPE	181	177	257

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0267 (Fisher's exact test), Q value = 0.29

Table S317. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MUC17 MUTATED	9	4	14	0
MUC17 WILD-TYPE	127	103	169	83

Figure S137. Get High-res Image Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0399 (Fisher's exact test), Q value = 0.38

Table S318. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MUC17 MUTATED	6	12	9
MUC17 WILD-TYPE	216	172	94

Figure S138. Get High-res Image Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0278 (Fisher's exact test), Q value = 0.3

Table S319. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MUC17 MUTATED	7	5	15
MUC17 WILD-TYPE	177	157	144

Figure S139. Get High-res Image Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'MUC17 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0616 (Fisher's exact test), Q value = 0.47

Table S320. Gene #26: 'MUC17 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MUC17 MUTATED	5	2	13	7
MUC17 WILD-TYPE	85	136	175	82

'PDGFRA MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0131 (Fisher's exact test), Q value = 0.19

Table S321. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PDGFRA MUTATED	1	6	2	1
PDGFRA WILD-TYPE	68	37	72	53

Figure S140. Get High-res Image Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'PDGFRA MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.148 (Fisher's exact test), Q value = 0.77

Table S322. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PDGFRA MUTATED	1	5	2	2
PDGFRA WILD-TYPE	62	45	46	77

'PDGFRA MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.904 (Fisher's exact test), Q value = 1

Table S323. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PDGFRA MUTATED	4	3	2	2
PDGFRA WILD-TYPE	73	90	43	58

'PDGFRA MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.137 (Fisher's exact test), Q value = 0.74

Table S324. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PDGFRA MUTATED	9	1	1
PDGFRA WILD-TYPE	129	60	75

'PDGFRA MUTATION STATUS' versus 'CN_CNMF'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S325. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PDGFRA MUTATED	10	11	0
PDGFRA WILD-TYPE	285	470	7

'PDGFRA MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 0.97

Table S326. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PDGFRA MUTATED	6	4	0	2
PDGFRA WILD-TYPE	154	228	64	164

'PDGFRA MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.147 (Fisher's exact test), Q value = 0.77

Table S327. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PDGFRA MUTATED	6	1	6
PDGFRA WILD-TYPE	189	185	183

'PDGFRA MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00749 (Fisher's exact test), Q value = 0.13

Table S328. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PDGFRA MUTATED	10	1	2
PDGFRA WILD-TYPE	194	218	145

Figure S141. Get High-res Image Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00403 (Fisher's exact test), Q value = 0.082

Table S329. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PDGFRA MUTATED	12	3	1
PDGFRA WILD-TYPE	215	232	191

Figure S142. Get High-res Image Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'PDGFRA MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0234 (Fisher's exact test), Q value = 0.27

Table S330. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PDGFRA MUTATED	9	5	2
PDGFRA WILD-TYPE	187	185	266

Figure S143. Get High-res Image Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.00063 (Fisher's exact test), Q value = 0.018

Table S331. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PDGFRA MUTATED	1	7	0	2
PDGFRA WILD-TYPE	135	100	183	81

Figure S144. Get High-res Image Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00147 (Fisher's exact test), Q value = 0.036

Table S332. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PDGFRA MUTATED	2	1	7
PDGFRA WILD-TYPE	220	183	96

Figure S145. Get High-res Image Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.851 (Fisher's exact test), Q value = 1

Table S333. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PDGFRA MUTATED	3	3	4
PDGFRA WILD-TYPE	181	159	155

'PDGFRA MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.186 (Fisher's exact test), Q value = 0.85

Table S334. Gene #27: 'PDGFRA MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PDGFRA MUTATED	0	2	4	4
PDGFRA WILD-TYPE	90	136	184	85

'NUP210L MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.81 (Fisher's exact test), Q value = 1

Table S335. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
NUP210L MUTATED	1	2	2	1
NUP210L WILD-TYPE	68	41	72	53

'NUP210L MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S336. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
NUP210L MUTATED	0	2	1	3
NUP210L WILD-TYPE	63	48	47	76

'NUP210L MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S337. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
NUP210L MUTATED	3	3	2	0
NUP210L WILD-TYPE	74	90	43	60

'NUP210L MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S338. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
NUP210L MUTATED	5	0	3
NUP210L WILD-TYPE	133	61	73

'NUP210L MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.85

Table S339. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NUP210L MUTATED	7	4	0
NUP210L WILD-TYPE	288	477	7

'NUP210L MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0128 (Fisher's exact test), Q value = 0.19

Table S340. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NUP210L MUTATED	7	1	0	1
NUP210L WILD-TYPE	153	231	64	165

Figure S146. Get High-res Image Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'NUP210L MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S341. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NUP210L MUTATED	2	4	3
NUP210L WILD-TYPE	193	182	186

'NUP210L MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S342. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NUP210L MUTATED	3	4	2
NUP210L WILD-TYPE	201	215	145

'NUP210L MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0163 (Fisher's exact test), Q value = 0.22

Table S343. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NUP210L MUTATED	6	0	2
NUP210L WILD-TYPE	221	235	190

Figure S147. Get High-res Image Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'NUP210L MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.205 (Fisher's exact test), Q value = 0.85

Table S344. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NUP210L MUTATED	5	1	2
NUP210L WILD-TYPE	191	189	266

'NUP210L MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S345. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NUP210L MUTATED	0	2	2	0
NUP210L WILD-TYPE	136	105	181	83

'NUP210L MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0765 (Fisher's exact test), Q value = 0.53

Table S346. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NUP210L MUTATED	0	2	2
NUP210L WILD-TYPE	222	182	101

'NUP210L MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 0.81

Table S347. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NUP210L MUTATED	1	0	3
NUP210L WILD-TYPE	183	162	156

'NUP210L MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.357 (Fisher's exact test), Q value = 1

Table S348. Gene #28: 'NUP210L MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NUP210L MUTATED	0	0	3	1
NUP210L WILD-TYPE	90	138	185	88

'IRS4 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.67

Table S349. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
IRS4 MUTATED	1	2	0	0
IRS4 WILD-TYPE	68	41	74	54

'IRS4 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S350. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
IRS4 MUTATED	1	1	0	1
IRS4 WILD-TYPE	62	49	48	78

'IRS4 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0523 (Fisher's exact test), Q value = 0.43

Table S351. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
IRS4 MUTATED	3	0	0	0
IRS4 WILD-TYPE	74	93	45	60

'IRS4 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.121 (Fisher's exact test), Q value = 0.68

Table S352. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
IRS4 MUTATED	0	1	2
IRS4 WILD-TYPE	138	60	74

'IRS4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.77 (Fisher's exact test), Q value = 1

Table S353. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
IRS4 MUTATED	3	7	0
IRS4 WILD-TYPE	292	474	7

'IRS4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.693 (Fisher's exact test), Q value = 1

Table S354. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
IRS4 MUTATED	3	3	1	1
IRS4 WILD-TYPE	157	229	63	165

'IRS4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.466 (Fisher's exact test), Q value = 1

Table S355. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
IRS4 MUTATED	4	2	1
IRS4 WILD-TYPE	191	184	188

'IRS4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.706 (Fisher's exact test), Q value = 1

Table S356. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
IRS4 MUTATED	2	4	1
IRS4 WILD-TYPE	202	215	146

'IRS4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.671 (Fisher's exact test), Q value = 1

Table S357. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
IRS4 MUTATED	5	3	2
IRS4 WILD-TYPE	222	232	190

'IRS4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.238 (Fisher's exact test), Q value = 0.91

Table S358. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
IRS4 MUTATED	3	5	2
IRS4 WILD-TYPE	193	185	266

'IRS4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S359. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IRS4 MUTATED	1	3	3	0
IRS4 WILD-TYPE	135	104	180	83

'IRS4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S360. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IRS4 MUTATED	2	3	2
IRS4 WILD-TYPE	220	181	101

'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.268 (Fisher's exact test), Q value = 0.95

Table S361. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IRS4 MUTATED	1	2	4
IRS4 WILD-TYPE	183	160	155

'IRS4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S362. Gene #29: 'IRS4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IRS4 MUTATED	1	2	3	1
IRS4 WILD-TYPE	89	136	185	88

'NKD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S363. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NKD2 MUTATED	1	3	0
NKD2 WILD-TYPE	294	478	7

'NKD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S364. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NKD2 MUTATED	1	2	0	1
NKD2 WILD-TYPE	159	230	64	165

'NKD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.397 (Fisher's exact test), Q value = 1

Table S365. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NKD2 MUTATED	1	3	0
NKD2 WILD-TYPE	226	232	192

'NKD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S366. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NKD2 MUTATED	1	1	2
NKD2 WILD-TYPE	195	189	266

'NKD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S367. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NKD2 MUTATED	0	2	1	1
NKD2 WILD-TYPE	136	105	182	82

'NKD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S368. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NKD2 MUTATED	2	1	1
NKD2 WILD-TYPE	220	183	102

'NKD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S369. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NKD2 MUTATED	2	1	1
NKD2 WILD-TYPE	182	161	158

'NKD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S370. Gene #30: 'NKD2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NKD2 MUTATED	1	1	1	1
NKD2 WILD-TYPE	89	137	187	88

'MED9 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S371. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MED9 MUTATED	1	2	0
MED9 WILD-TYPE	294	479	7

'MED9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S372. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MED9 MUTATED	0	1	1	1
MED9 WILD-TYPE	160	231	63	165

'MED9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0351 (Fisher's exact test), Q value = 0.35

Table S373. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MED9 MUTATED	0	3	0
MED9 WILD-TYPE	195	183	189

Figure S148. Get High-res Image Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'MED9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.95

Table S374. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MED9 MUTATED	0	1	2
MED9 WILD-TYPE	204	218	145

'MED9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.97

Table S375. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MED9 MUTATED	0	1	2
MED9 WILD-TYPE	227	234	190

'MED9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S376. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MED9 MUTATED	1	1	1
MED9 WILD-TYPE	195	189	267

'MED9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S377. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MED9 MUTATED	1	0	2	0
MED9 WILD-TYPE	135	107	181	83

'MED9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.796 (Fisher's exact test), Q value = 1

Table S378. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MED9 MUTATED	1	1	1
MED9 WILD-TYPE	221	183	102

'MED9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 1

Table S379. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MED9 MUTATED	2	0	1
MED9 WILD-TYPE	182	162	158

'MED9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S380. Gene #31: 'MED9 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MED9 MUTATED	0	0	2	1
MED9 WILD-TYPE	90	138	186	88

'HTRA2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.85

Table S381. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
HTRA2 MUTATED	0	5	0
HTRA2 WILD-TYPE	295	476	7

'HTRA2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S382. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
HTRA2 MUTATED	0	3	1	1
HTRA2 WILD-TYPE	160	229	63	165

'HTRA2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.95

Table S383. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
HTRA2 MUTATED	3	1	0
HTRA2 WILD-TYPE	192	185	189

'HTRA2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S384. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
HTRA2 MUTATED	2	1	1
HTRA2 WILD-TYPE	202	218	146

'HTRA2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.863 (Fisher's exact test), Q value = 1

Table S385. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
HTRA2 MUTATED	1	2	2
HTRA2 WILD-TYPE	226	233	190

'HTRA2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S386. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
HTRA2 MUTATED	1	2	2
HTRA2 WILD-TYPE	195	188	266

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.348 (Fisher's exact test), Q value = 1

Table S387. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HTRA2 MUTATED	3	0	1	1
HTRA2 WILD-TYPE	133	107	182	82

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S388. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HTRA2 MUTATED	3	2	0
HTRA2 WILD-TYPE	219	182	103

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.555 (Fisher's exact test), Q value = 1

Table S389. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HTRA2 MUTATED	2	2	0
HTRA2 WILD-TYPE	182	160	159

'HTRA2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.468 (Fisher's exact test), Q value = 1

Table S390. Gene #32: 'HTRA2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HTRA2 MUTATED	2	1	1	0
HTRA2 WILD-TYPE	88	137	187	89

'BCOR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.64 (Fisher's exact test), Q value = 1

Table S391. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
BCOR MUTATED	1	1	2	3
BCOR WILD-TYPE	68	42	72	51

'BCOR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S392. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
BCOR MUTATED	0	2	2	3
BCOR WILD-TYPE	63	48	46	76

'BCOR MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 0.63

Table S393. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
BCOR MUTATED	0	2	3	2
BCOR WILD-TYPE	77	91	42	58

'BCOR MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S394. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
BCOR MUTATED	5	1	1
BCOR WILD-TYPE	133	60	75

'BCOR MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S395. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
BCOR MUTATED	8	14	0
BCOR WILD-TYPE	287	467	7

'BCOR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.653 (Fisher's exact test), Q value = 1

Table S396. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
BCOR MUTATED	4	5	1	7
BCOR WILD-TYPE	156	227	63	159

'BCOR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S397. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
BCOR MUTATED	4	3	7
BCOR WILD-TYPE	191	183	182

'BCOR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.889 (Fisher's exact test), Q value = 1

Table S398. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
BCOR MUTATED	6	5	3
BCOR WILD-TYPE	198	214	144

'BCOR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.277 (Fisher's exact test), Q value = 0.95

Table S399. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
BCOR MUTATED	5	4	8
BCOR WILD-TYPE	222	231	184

'BCOR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S400. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
BCOR MUTATED	3	4	10
BCOR WILD-TYPE	193	186	258

'BCOR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S401. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
BCOR MUTATED	5	3	6	1
BCOR WILD-TYPE	131	104	177	82

'BCOR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S402. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
BCOR MUTATED	5	6	4
BCOR WILD-TYPE	217	178	99

'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S403. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
BCOR MUTATED	4	6	5
BCOR WILD-TYPE	180	156	154

'BCOR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.949 (Fisher's exact test), Q value = 1

Table S404. Gene #33: 'BCOR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
BCOR MUTATED	2	5	6	2
BCOR WILD-TYPE	88	133	182	87

'REN MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S405. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
REN MUTATED	0	0	2	1
REN WILD-TYPE	69	43	72	53

'REN MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.417 (Fisher's exact test), Q value = 1

Table S406. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
REN MUTATED	0	0	1	2
REN WILD-TYPE	63	50	47	77

'REN MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0734 (Fisher's exact test), Q value = 0.52

Table S407. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
REN MUTATED	1	1	3	0
REN WILD-TYPE	76	92	42	60

'REN MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S408. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
REN MUTATED	4	0	1
REN WILD-TYPE	134	61	75

'REN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00281 (Fisher's exact test), Q value = 0.062

Table S409. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
REN MUTATED	7	0	0
REN WILD-TYPE	288	481	7

Figure S149. Get High-res Image Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'REN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00269 (Fisher's exact test), Q value = 0.06

Table S410. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
REN MUTATED	5	0	0	0
REN WILD-TYPE	155	232	64	166

Figure S150. Get High-res Image Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'REN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.458 (Fisher's exact test), Q value = 1

Table S411. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
REN MUTATED	1	3	2
REN WILD-TYPE	194	183	187

'REN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S412. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
REN MUTATED	2	3	1
REN WILD-TYPE	202	216	146

'REN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.85

Table S413. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
REN MUTATED	1	0	2
REN WILD-TYPE	226	235	190

'REN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S414. Gene #34: 'REN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
REN MUTATED	1	0	2
REN WILD-TYPE	195	190	266

'RBPJ MUTATION STATUS' versus 'CN_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 0.65

Table S415. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
RBPJ MUTATED	0	7	0
RBPJ WILD-TYPE	295	474	7

'RBPJ MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0397 (Fisher's exact test), Q value = 0.38

Table S416. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
RBPJ MUTATED	0	1	1	5
RBPJ WILD-TYPE	160	231	63	161

Figure S151. Get High-res Image Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'RBPJ MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S417. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
RBPJ MUTATED	3	0	2
RBPJ WILD-TYPE	192	186	187

'RBPJ MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.00677 (Fisher's exact test), Q value = 0.12

Table S418. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
RBPJ MUTATED	5	0	0
RBPJ WILD-TYPE	199	219	147

Figure S152. Get High-res Image Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'RBPJ MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0269 (Fisher's exact test), Q value = 0.29

Table S419. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
RBPJ MUTATED	2	0	5
RBPJ WILD-TYPE	225	235	187

Figure S153. Get High-res Image Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'RBPJ MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.142 (Fisher's exact test), Q value = 0.75

Table S420. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
RBPJ MUTATED	0	2	5
RBPJ WILD-TYPE	196	188	263

'RBPJ MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S421. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RBPJ MUTATED	0	2	4	1
RBPJ WILD-TYPE	136	105	179	82

'RBPJ MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0287 (Fisher's exact test), Q value = 0.3

Table S422. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RBPJ MUTATED	0	5	2
RBPJ WILD-TYPE	222	179	101

Figure S154. Get High-res Image Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'RBPJ MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.67

Table S423. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RBPJ MUTATED	1	1	5
RBPJ WILD-TYPE	183	161	154

'RBPJ MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S424. Gene #35: 'RBPJ MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RBPJ MUTATED	0	1	4	2
RBPJ WILD-TYPE	90	137	184	87

'DDX5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.211 (Fisher's exact test), Q value = 0.86

Table S425. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
DDX5 MUTATED	1	0	0	2
DDX5 WILD-TYPE	68	43	74	52

'DDX5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S426. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
DDX5 MUTATED	1	1	0	1
DDX5 WILD-TYPE	62	49	48	78

'DDX5 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S427. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
DDX5 MUTATED	0	2	1	1
DDX5 WILD-TYPE	77	91	44	59

'DDX5 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.445 (Fisher's exact test), Q value = 1

Table S428. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
DDX5 MUTATED	1	1	2
DDX5 WILD-TYPE	137	60	74

'DDX5 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S429. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
DDX5 MUTATED	3	6	0
DDX5 WILD-TYPE	292	475	7

'DDX5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.677 (Fisher's exact test), Q value = 1

Table S430. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
DDX5 MUTATED	3	2	0	2
DDX5 WILD-TYPE	157	230	64	164

'DDX5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S431. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
DDX5 MUTATED	4	2	1
DDX5 WILD-TYPE	191	184	188

'DDX5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.565 (Fisher's exact test), Q value = 1

Table S432. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
DDX5 MUTATED	4	2	1
DDX5 WILD-TYPE	200	217	146

'DDX5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S433. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
DDX5 MUTATED	2	3	1
DDX5 WILD-TYPE	225	232	191

'DDX5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S434. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
DDX5 MUTATED	1	3	2
DDX5 WILD-TYPE	195	187	266

'DDX5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 0.95

Table S435. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DDX5 MUTATED	0	2	3	0
DDX5 WILD-TYPE	136	105	180	83

'DDX5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.441 (Fisher's exact test), Q value = 1

Table S436. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DDX5 MUTATED	1	3	1
DDX5 WILD-TYPE	221	181	102

'DDX5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0276 (Fisher's exact test), Q value = 0.3

Table S437. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DDX5 MUTATED	0	1	4
DDX5 WILD-TYPE	184	161	155

Figure S155. Get High-res Image Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'DDX5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 0.99

Table S438. Gene #36: 'DDX5 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DDX5 MUTATED	0	1	4	0
DDX5 WILD-TYPE	90	137	184	89

'PTPN11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S439. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PTPN11 MUTATED	1	0	1	1
PTPN11 WILD-TYPE	68	43	73	53

'PTPN11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S440. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PTPN11 MUTATED	1	0	0	2
PTPN11 WILD-TYPE	62	50	48	77

'PTPN11 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.00638 (Fisher's exact test), Q value = 0.12

Table S441. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PTPN11 MUTATED	0	0	3	1
PTPN11 WILD-TYPE	77	93	42	59

Figure S156. Get High-res Image Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'PTPN11 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S442. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PTPN11 MUTATED	2	1	1
PTPN11 WILD-TYPE	136	60	75

'PTPN11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.561 (Fisher's exact test), Q value = 1

Table S443. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PTPN11 MUTATED	5	5	0
PTPN11 WILD-TYPE	290	476	7

'PTPN11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0316 (Fisher's exact test), Q value = 0.32

Table S444. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PTPN11 MUTATED	4	1	3	1
PTPN11 WILD-TYPE	156	231	61	165

Figure S157. Get High-res Image Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PTPN11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S445. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PTPN11 MUTATED	3	2	3
PTPN11 WILD-TYPE	192	184	186

'PTPN11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.26 (Fisher's exact test), Q value = 0.95

Table S446. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PTPN11 MUTATED	5	1	2
PTPN11 WILD-TYPE	199	218	145

'PTPN11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 0.89

Table S447. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PTPN11 MUTATED	5	1	3
PTPN11 WILD-TYPE	222	234	189

'PTPN11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 0.95

Table S448. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PTPN11 MUTATED	5	2	2
PTPN11 WILD-TYPE	191	188	266

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.88

Table S449. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PTPN11 MUTATED	3	3	1	0
PTPN11 WILD-TYPE	133	104	182	83

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00544 (Fisher's exact test), Q value = 0.1

Table S450. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PTPN11 MUTATED	1	1	5
PTPN11 WILD-TYPE	221	183	98

Figure S158. Get High-res Image Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0161 (Fisher's exact test), Q value = 0.22

Table S451. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PTPN11 MUTATED	6	0	1
PTPN11 WILD-TYPE	178	162	158

Figure S159. Get High-res Image Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'PTPN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00229 (Fisher's exact test), Q value = 0.052

Table S452. Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PTPN11 MUTATED	1	0	1	5
PTPN11 WILD-TYPE	89	138	187	84

Figure S160. Get High-res Image Gene #37: 'PTPN11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'KDR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.205 (Fisher's exact test), Q value = 0.85

Table S453. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
KDR MUTATED	1	2	1	4
KDR WILD-TYPE	68	41	73	50

'KDR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.657 (Fisher's exact test), Q value = 1

Table S454. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
KDR MUTATED	1	3	1	3
KDR WILD-TYPE	62	47	47	76

'KDR MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.95

Table S455. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
KDR MUTATED	2	1	3	2
KDR WILD-TYPE	75	92	42	58

'KDR MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S456. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
KDR MUTATED	6	1	1
KDR WILD-TYPE	132	60	75

'KDR MUTATION STATUS' versus 'CN_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S457. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KDR MUTATED	8	5	0
KDR WILD-TYPE	287	476	7

'KDR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0369 (Fisher's exact test), Q value = 0.36

Table S458. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KDR MUTATED	6	1	0	1
KDR WILD-TYPE	154	231	64	165

Figure S161. Get High-res Image Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'KDR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S459. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
KDR MUTATED	4	2	4
KDR WILD-TYPE	191	184	185

'KDR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0952 (Fisher's exact test), Q value = 0.6

Table S460. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
KDR MUTATED	7	2	1
KDR WILD-TYPE	197	217	146

'KDR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.102 (Fisher's exact test), Q value = 0.63

Table S461. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KDR MUTATED	4	0	2
KDR WILD-TYPE	223	235	190

'KDR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S462. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KDR MUTATED	3	1	2
KDR WILD-TYPE	193	189	266

'KDR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 0.95

Table S463. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KDR MUTATED	0	2	3	0
KDR WILD-TYPE	136	105	180	83

'KDR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.023 (Fisher's exact test), Q value = 0.27

Table S464. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KDR MUTATED	0	2	3
KDR WILD-TYPE	222	182	100

Figure S162. Get High-res Image Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'KDR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.239 (Fisher's exact test), Q value = 0.91

Table S465. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KDR MUTATED	2	0	3
KDR WILD-TYPE	182	162	156

'KDR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S466. Gene #38: 'KDR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KDR MUTATED	0	0	3	2
KDR WILD-TYPE	90	138	185	87

'RPL5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.381 (Fisher's exact test), Q value = 1

Table S467. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
RPL5 MUTATED	1	2	3	0
RPL5 WILD-TYPE	68	41	71	54

'RPL5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S468. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
RPL5 MUTATED	3	0	1	2
RPL5 WILD-TYPE	60	50	47	77

'RPL5 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S469. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
RPL5 MUTATED	1	3	1	2
RPL5 WILD-TYPE	76	90	44	58

'RPL5 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.469 (Fisher's exact test), Q value = 1

Table S470. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
RPL5 MUTATED	3	3	1
RPL5 WILD-TYPE	135	58	75

'RPL5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.261 (Fisher's exact test), Q value = 0.95

Table S471. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
RPL5 MUTATED	6	4	0
RPL5 WILD-TYPE	289	477	7

'RPL5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.014 (Fisher's exact test), Q value = 0.19

Table S472. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
RPL5 MUTATED	5	0	0	1
RPL5 WILD-TYPE	155	232	64	165

Figure S163. Get High-res Image Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'RPL5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S473. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
RPL5 MUTATED	4	1	2
RPL5 WILD-TYPE	191	185	187

'RPL5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S474. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
RPL5 MUTATED	3	3	1
RPL5 WILD-TYPE	201	216	146

'RPL5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0223 (Fisher's exact test), Q value = 0.26

Table S475. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
RPL5 MUTATED	5	0	1
RPL5 WILD-TYPE	222	235	191

Figure S164. Get High-res Image Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'RPL5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.188 (Fisher's exact test), Q value = 0.85

Table S476. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
RPL5 MUTATED	4	1	1
RPL5 WILD-TYPE	192	189	267

'RPL5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0894 (Fisher's exact test), Q value = 0.59

Table S477. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RPL5 MUTATED	0	2	0	1
RPL5 WILD-TYPE	136	105	183	82

'RPL5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0527 (Fisher's exact test), Q value = 0.43

Table S478. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RPL5 MUTATED	0	1	2
RPL5 WILD-TYPE	222	183	101

'RPL5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S479. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RPL5 MUTATED	1	1	1
RPL5 WILD-TYPE	183	161	158

'RPL5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S480. Gene #39: 'RPL5 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RPL5 MUTATED	0	0	2	1
RPL5 WILD-TYPE	90	138	186	88

'NRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S481. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NRAS MUTATED	1	4	0
NRAS WILD-TYPE	294	477	7

'NRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.252 (Fisher's exact test), Q value = 0.94

Table S482. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NRAS MUTATED	0	1	0	3
NRAS WILD-TYPE	160	231	64	163

'NRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.21 (Fisher's exact test), Q value = 0.86

Table S483. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NRAS MUTATED	0	2	3
NRAS WILD-TYPE	195	184	186

'NRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.855 (Fisher's exact test), Q value = 1

Table S484. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NRAS MUTATED	1	2	2
NRAS WILD-TYPE	203	217	145

'NRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.109 (Fisher's exact test), Q value = 0.65

Table S485. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NRAS MUTATED	0	1	3
NRAS WILD-TYPE	227	234	189

'NRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.98

Table S486. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NRAS MUTATED	0	1	3
NRAS WILD-TYPE	196	189	265

'NRAS MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.98

Table S487. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NRAS MUTATED	0	0	3	1
NRAS WILD-TYPE	136	107	180	82

'NRAS MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S488. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NRAS MUTATED	1	2	1
NRAS WILD-TYPE	221	182	102

'NRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.333 (Fisher's exact test), Q value = 1

Table S489. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NRAS MUTATED	0	2	2
NRAS WILD-TYPE	184	160	157

'NRAS MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S490. Gene #40: 'NRAS MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NRAS MUTATED	0	2	2	0
NRAS WILD-TYPE	90	136	186	89

'TPX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.731 (Fisher's exact test), Q value = 1

Table S491. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TPX2 MUTATED	2	5	0
TPX2 WILD-TYPE	293	476	7

'TPX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S492. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TPX2 MUTATED	3	3	0	1
TPX2 WILD-TYPE	157	229	64	165

'TPX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S493. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TPX2 MUTATED	1	2	1
TPX2 WILD-TYPE	194	184	188

'TPX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S494. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TPX2 MUTATED	1	2	1
TPX2 WILD-TYPE	203	217	146

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S495. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TPX2 MUTATED	2	2	2
TPX2 WILD-TYPE	225	233	190

'TPX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.591 (Fisher's exact test), Q value = 1

Table S496. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TPX2 MUTATED	1	3	2
TPX2 WILD-TYPE	195	187	266

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.492 (Fisher's exact test), Q value = 1

Table S497. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TPX2 MUTATED	0	1	3	1
TPX2 WILD-TYPE	136	106	180	82

'TPX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0713 (Fisher's exact test), Q value = 0.51

Table S498. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TPX2 MUTATED	0	4	1
TPX2 WILD-TYPE	222	180	102

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 0.81

Table S499. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TPX2 MUTATED	0	2	3
TPX2 WILD-TYPE	184	160	156

'TPX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.316 (Fisher's exact test), Q value = 0.99

Table S500. Gene #41: 'TPX2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TPX2 MUTATED	0	1	4	0
TPX2 WILD-TYPE	90	137	184	89

'EMG1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 0.73

Table S501. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
EMG1 MUTATED	0	6	0
EMG1 WILD-TYPE	295	475	7

'EMG1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.372 (Fisher's exact test), Q value = 1

Table S502. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
EMG1 MUTATED	0	3	0	3
EMG1 WILD-TYPE	160	229	64	163

'EMG1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 0.89

Table S503. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
EMG1 MUTATED	3	3	0
EMG1 WILD-TYPE	192	183	189

'EMG1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S504. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
EMG1 MUTATED	3	2	1
EMG1 WILD-TYPE	201	217	146

'EMG1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.75

Table S505. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
EMG1 MUTATED	0	4	2
EMG1 WILD-TYPE	227	231	190

'EMG1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0965 (Fisher's exact test), Q value = 0.61

Table S506. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
EMG1 MUTATED	0	1	5
EMG1 WILD-TYPE	196	189	263

'EMG1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.408 (Fisher's exact test), Q value = 1

Table S507. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
EMG1 MUTATED	1	0	3	2
EMG1 WILD-TYPE	135	107	180	81

'EMG1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S508. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
EMG1 MUTATED	4	2	0
EMG1 WILD-TYPE	218	182	103

'EMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S509. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
EMG1 MUTATED	1	3	2
EMG1 WILD-TYPE	183	159	157

'EMG1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.725 (Fisher's exact test), Q value = 1

Table S510. Gene #42: 'EMG1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
EMG1 MUTATED	1	3	2	0
EMG1 WILD-TYPE	89	135	186	89

'BRAF MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S511. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
BRAF MUTATED	1	1	2	0
BRAF WILD-TYPE	68	42	72	54

'BRAF MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S512. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
BRAF MUTATED	2	0	1	1
BRAF WILD-TYPE	61	50	47	78

'BRAF MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.317 (Fisher's exact test), Q value = 0.99

Table S513. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
BRAF MUTATED	2	1	0	3
BRAF WILD-TYPE	75	92	45	57

'BRAF MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0288 (Fisher's exact test), Q value = 0.3

Table S514. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
BRAF MUTATED	2	4	0
BRAF WILD-TYPE	136	57	76

Figure S165. Get High-res Image Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'BRAF MUTATION STATUS' versus 'CN_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S515. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
BRAF MUTATED	6	5	0
BRAF WILD-TYPE	289	476	7

'BRAF MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00025 (Fisher's exact test), Q value = 0.0073

Table S516. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
BRAF MUTATED	3	0	4	0
BRAF WILD-TYPE	157	232	60	166

Figure S166. Get High-res Image Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'BRAF MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S517. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
BRAF MUTATED	3	4	1
BRAF WILD-TYPE	192	182	188

'BRAF MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.291 (Fisher's exact test), Q value = 0.97

Table S518. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
BRAF MUTATED	4	1	3
BRAF WILD-TYPE	200	218	144

'BRAF MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0499 (Fisher's exact test), Q value = 0.43

Table S519. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
BRAF MUTATED	5	0	3
BRAF WILD-TYPE	222	235	189

Figure S167. Get High-res Image Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'BRAF MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S520. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
BRAF MUTATED	4	1	3
BRAF WILD-TYPE	192	189	265

'BRAF MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.263 (Fisher's exact test), Q value = 0.95

Table S521. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
BRAF MUTATED	0	2	3	0
BRAF WILD-TYPE	136	105	180	83

'BRAF MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0902 (Fisher's exact test), Q value = 0.59

Table S522. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
BRAF MUTATED	0	3	2
BRAF WILD-TYPE	222	181	101

'BRAF MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0632 (Fisher's exact test), Q value = 0.48

Table S523. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
BRAF MUTATED	1	0	4
BRAF WILD-TYPE	183	162	155

'BRAF MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.196 (Fisher's exact test), Q value = 0.85

Table S524. Gene #43: 'BRAF MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
BRAF MUTATED	0	0	3	2
BRAF WILD-TYPE	90	138	185	87

'MX2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S525. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
MX2 MUTATED	2	0	2	0
MX2 WILD-TYPE	67	43	72	54

'MX2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.84 (Fisher's exact test), Q value = 1

Table S526. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MX2 MUTATED	1	0	1	2
MX2 WILD-TYPE	62	50	47	77

'MX2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S527. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
MX2 MUTATED	2	0	1	1
MX2 WILD-TYPE	75	93	44	59

'MX2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S528. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MX2 MUTATED	1	1	2
MX2 WILD-TYPE	137	60	74

'MX2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S529. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MX2 MUTATED	5	4	0
MX2 WILD-TYPE	290	477	7

'MX2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S530. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MX2 MUTATED	2	1	0	2
MX2 WILD-TYPE	158	231	64	164

'MX2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S531. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MX2 MUTATED	3	1	2
MX2 WILD-TYPE	192	185	187

'MX2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.404 (Fisher's exact test), Q value = 1

Table S532. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MX2 MUTATED	3	3	0
MX2 WILD-TYPE	201	216	147

'MX2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S533. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MX2 MUTATED	1	2	1
MX2 WILD-TYPE	226	233	191

'MX2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S534. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MX2 MUTATED	1	1	2
MX2 WILD-TYPE	195	189	266

'MX2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.367 (Fisher's exact test), Q value = 1

Table S535. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MX2 MUTATED	0	2	1	1
MX2 WILD-TYPE	136	105	182	82

'MX2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S536. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MX2 MUTATED	2	1	1
MX2 WILD-TYPE	220	183	102

'MX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S537. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MX2 MUTATED	2	1	1
MX2 WILD-TYPE	182	161	158

'MX2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S538. Gene #44: 'MX2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MX2 MUTATED	0	2	1	1
MX2 WILD-TYPE	90	136	187	88

'FAM47C MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S539. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
FAM47C MUTATED	0	0	2	1
FAM47C WILD-TYPE	69	43	72	53

'FAM47C MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0582 (Fisher's exact test), Q value = 0.46

Table S540. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FAM47C MUTATED	0	1	2	0
FAM47C WILD-TYPE	63	49	46	79

'FAM47C MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S541. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
FAM47C MUTATED	1	2	2	0
FAM47C WILD-TYPE	76	91	43	60

'FAM47C MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S542. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FAM47C MUTATED	2	1	2
FAM47C WILD-TYPE	136	60	74

'FAM47C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S543. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
FAM47C MUTATED	5	17	0
FAM47C WILD-TYPE	290	464	7

'FAM47C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S544. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
FAM47C MUTATED	3	7	3	7
FAM47C WILD-TYPE	157	225	61	159

'FAM47C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S545. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
FAM47C MUTATED	7	6	5
FAM47C WILD-TYPE	188	180	184

'FAM47C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S546. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
FAM47C MUTATED	6	6	6
FAM47C WILD-TYPE	198	213	141

'FAM47C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0512 (Fisher's exact test), Q value = 0.43

Table S547. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
FAM47C MUTATED	5	4	11
FAM47C WILD-TYPE	222	231	181

'FAM47C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0047 (Fisher's exact test), Q value = 0.092

Table S548. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
FAM47C MUTATED	4	1	15
FAM47C WILD-TYPE	192	189	253

Figure S168. Get High-res Image Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'FAM47C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S549. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FAM47C MUTATED	3	4	9	2
FAM47C WILD-TYPE	133	103	174	81

'FAM47C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0916 (Fisher's exact test), Q value = 0.59

Table S550. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FAM47C MUTATED	5	11	2
FAM47C WILD-TYPE	217	173	101

'FAM47C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.00856 (Fisher's exact test), Q value = 0.14

Table S551. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FAM47C MUTATED	3	3	12
FAM47C WILD-TYPE	181	159	147

Figure S169. Get High-res Image Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'FAM47C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.00345 (Fisher's exact test), Q value = 0.072

Table S552. Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FAM47C MUTATED	0	3	14	1
FAM47C WILD-TYPE	90	135	174	88

Figure S170. Get High-res Image Gene #45: 'FAM47C MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'TRERF1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 0.98

Table S553. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TRERF1 MUTATED	1	6	0
TRERF1 WILD-TYPE	294	475	7

'TRERF1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S554. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TRERF1 MUTATED	2	3	1	1
TRERF1 WILD-TYPE	158	229	63	165

'TRERF1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S555. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TRERF1 MUTATED	3	2	1
TRERF1 WILD-TYPE	192	184	188

'TRERF1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S556. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TRERF1 MUTATED	3	2	1
TRERF1 WILD-TYPE	201	217	146

'TRERF1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S557. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TRERF1 MUTATED	2	2	2
TRERF1 WILD-TYPE	225	233	190

'TRERF1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0182 (Fisher's exact test), Q value = 0.23

Table S558. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TRERF1 MUTATED	0	5	1
TRERF1 WILD-TYPE	196	185	267

Figure S171. Get High-res Image Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.387 (Fisher's exact test), Q value = 1

Table S559. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TRERF1 MUTATED	1	3	2	0
TRERF1 WILD-TYPE	135	104	181	83

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S560. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TRERF1 MUTATED	2	2	2
TRERF1 WILD-TYPE	220	182	101

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.104 (Fisher's exact test), Q value = 0.64

Table S561. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TRERF1 MUTATED	2	0	4
TRERF1 WILD-TYPE	182	162	155

'TRERF1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S562. Gene #46: 'TRERF1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TRERF1 MUTATED	1	0	4	1
TRERF1 WILD-TYPE	89	138	184	88

'MYST4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.113 (Fisher's exact test), Q value = 0.66

Table S563. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MYST4 MUTATED	1	11	0
MYST4 WILD-TYPE	294	470	7

'MYST4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 0.63

Table S564. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MYST4 MUTATED	3	2	0	7
MYST4 WILD-TYPE	157	230	64	159

'MYST4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0826 (Fisher's exact test), Q value = 0.56

Table S565. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MYST4 MUTATED	7	2	1
MYST4 WILD-TYPE	188	184	188

'MYST4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.276 (Fisher's exact test), Q value = 0.95

Table S566. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MYST4 MUTATED	6	3	1
MYST4 WILD-TYPE	198	216	146

'MYST4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S567. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MYST4 MUTATED	2	4	5
MYST4 WILD-TYPE	225	231	187

'MYST4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.201 (Fisher's exact test), Q value = 0.85

Table S568. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MYST4 MUTATED	1	3	7
MYST4 WILD-TYPE	195	187	261

'MYST4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 0.85

Table S569. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MYST4 MUTATED	1	3	3	4
MYST4 WILD-TYPE	135	104	180	79

'MYST4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S570. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MYST4 MUTATED	5	4	2
MYST4 WILD-TYPE	217	180	101

'MYST4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0636 (Fisher's exact test), Q value = 0.48

Table S571. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MYST4 MUTATED	1	7	3
MYST4 WILD-TYPE	183	155	156

'MYST4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.612 (Fisher's exact test), Q value = 1

Table S572. Gene #47: 'MYST4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MYST4 MUTATED	1	5	4	1
MYST4 WILD-TYPE	89	133	184	88

'SRPX MUTATION STATUS' versus 'CN_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S573. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SRPX MUTATED	2	2	0
SRPX WILD-TYPE	293	479	7

'SRPX MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.283 (Fisher's exact test), Q value = 0.96

Table S574. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SRPX MUTATED	2	0	0	2
SRPX WILD-TYPE	158	232	64	164

'SRPX MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.554 (Fisher's exact test), Q value = 1

Table S575. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SRPX MUTATED	2	0	2
SRPX WILD-TYPE	193	186	187

'SRPX MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S576. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SRPX MUTATED	2	2	0
SRPX WILD-TYPE	202	217	147

'SRPX MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.557 (Fisher's exact test), Q value = 1

Table S577. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SRPX MUTATED	2	2	0
SRPX WILD-TYPE	225	233	192

'SRPX MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S578. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SRPX MUTATED	2	0	2
SRPX WILD-TYPE	194	190	266

'SRPX MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.95

Table S579. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SRPX MUTATED	2	1	0	1
SRPX WILD-TYPE	134	106	183	82

'SRPX MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S580. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SRPX MUTATED	2	0	2
SRPX WILD-TYPE	220	184	101

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S581. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SRPX MUTATED	3	1	0
SRPX WILD-TYPE	181	161	159

'SRPX MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.063 (Fisher's exact test), Q value = 0.48

Table S582. Gene #48: 'SRPX MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SRPX MUTATED	0	2	0	2
SRPX WILD-TYPE	90	136	188	87

'SETD2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00538 (Fisher's exact test), Q value = 0.1

Table S583. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
SETD2 MUTATED	0	3	0	0
SETD2 WILD-TYPE	69	40	74	54

Figure S172. Get High-res Image Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'SETD2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S584. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SETD2 MUTATED	2	1	0	0
SETD2 WILD-TYPE	61	49	48	79

'SETD2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.459 (Fisher's exact test), Q value = 1

Table S585. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
SETD2 MUTATED	1	0	1	1
SETD2 WILD-TYPE	76	93	44	59

'SETD2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S586. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SETD2 MUTATED	2	0	1
SETD2 WILD-TYPE	136	61	75

'SETD2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.624 (Fisher's exact test), Q value = 1

Table S587. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SETD2 MUTATED	6	7	0
SETD2 WILD-TYPE	289	474	7

'SETD2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.176 (Fisher's exact test), Q value = 0.83

Table S588. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SETD2 MUTATED	7	3	1	2
SETD2 WILD-TYPE	153	229	63	164

'SETD2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S589. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SETD2 MUTATED	4	3	3
SETD2 WILD-TYPE	191	183	186

'SETD2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S590. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SETD2 MUTATED	5	4	1
SETD2 WILD-TYPE	199	215	146

'SETD2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.108 (Fisher's exact test), Q value = 0.65

Table S591. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SETD2 MUTATED	8	2	3
SETD2 WILD-TYPE	219	233	189

'SETD2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.383 (Fisher's exact test), Q value = 1

Table S592. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SETD2 MUTATED	5	5	3
SETD2 WILD-TYPE	191	185	265

'SETD2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S593. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SETD2 MUTATED	2	4	3	1
SETD2 WILD-TYPE	134	103	180	82

'SETD2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.091 (Fisher's exact test), Q value = 0.59

Table S594. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SETD2 MUTATED	3	2	5
SETD2 WILD-TYPE	219	182	98

'SETD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S595. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SETD2 MUTATED	3	3	4
SETD2 WILD-TYPE	181	159	155

'SETD2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.379 (Fisher's exact test), Q value = 1

Table S596. Gene #49: 'SETD2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SETD2 MUTATED	1	2	3	4
SETD2 WILD-TYPE	89	136	185	85

'TNRC18 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.97

Table S597. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TNRC18 MUTATED	2	9	0
TNRC18 WILD-TYPE	293	472	7

'TNRC18 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S598. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TNRC18 MUTATED	2	5	2	1
TNRC18 WILD-TYPE	158	227	62	165

'TNRC18 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S599. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TNRC18 MUTATED	2	4	2
TNRC18 WILD-TYPE	193	182	187

'TNRC18 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S600. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TNRC18 MUTATED	3	2	3
TNRC18 WILD-TYPE	201	217	144

'TNRC18 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 0.88

Table S601. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TNRC18 MUTATED	3	2	6
TNRC18 WILD-TYPE	224	233	186

'TNRC18 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S602. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TNRC18 MUTATED	2	3	6
TNRC18 WILD-TYPE	194	187	262

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S603. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TNRC18 MUTATED	3	2	4	0
TNRC18 WILD-TYPE	133	105	179	83

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.377 (Fisher's exact test), Q value = 1

Table S604. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TNRC18 MUTATED	2	4	3
TNRC18 WILD-TYPE	220	180	100

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.821 (Fisher's exact test), Q value = 1

Table S605. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TNRC18 MUTATED	2	3	3
TNRC18 WILD-TYPE	182	159	156

'TNRC18 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S606. Gene #50: 'TNRC18 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TNRC18 MUTATED	0	2	4	2
TNRC18 WILD-TYPE	90	136	184	87

'SLC6A3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.62 (Fisher's exact test), Q value = 1

Table S607. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
SLC6A3 MUTATED	0	1	1	1
SLC6A3 WILD-TYPE	69	42	73	53

'SLC6A3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S608. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SLC6A3 MUTATED	0	1	1	1
SLC6A3 WILD-TYPE	63	49	47	78

'SLC6A3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S609. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
SLC6A3 MUTATED	0	2	1	0
SLC6A3 WILD-TYPE	77	91	44	60

'SLC6A3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S610. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SLC6A3 MUTATED	2	0	1
SLC6A3 WILD-TYPE	136	61	75

'SLC6A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.597 (Fisher's exact test), Q value = 1

Table S611. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SLC6A3 MUTATED	3	9	0
SLC6A3 WILD-TYPE	292	472	7

'SLC6A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S612. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SLC6A3 MUTATED	3	4	0	3
SLC6A3 WILD-TYPE	157	228	64	163

'SLC6A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.107 (Fisher's exact test), Q value = 0.65

Table S613. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SLC6A3 MUTATED	6	1	1
SLC6A3 WILD-TYPE	189	185	188

'SLC6A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0658 (Fisher's exact test), Q value = 0.49

Table S614. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SLC6A3 MUTATED	6	2	0
SLC6A3 WILD-TYPE	198	217	147

'SLC6A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S615. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SLC6A3 MUTATED	3	4	3
SLC6A3 WILD-TYPE	224	231	189

'SLC6A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.674 (Fisher's exact test), Q value = 1

Table S616. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SLC6A3 MUTATED	2	4	4
SLC6A3 WILD-TYPE	194	186	264

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.174 (Fisher's exact test), Q value = 0.83

Table S617. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC6A3 MUTATED	2	4	1	2
SLC6A3 WILD-TYPE	134	103	182	81

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.507 (Fisher's exact test), Q value = 1

Table S618. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC6A3 MUTATED	4	2	3
SLC6A3 WILD-TYPE	218	182	100

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S619. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC6A3 MUTATED	3	2	4
SLC6A3 WILD-TYPE	181	160	155

'SLC6A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S620. Gene #51: 'SLC6A3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC6A3 MUTATED	3	1	4	1
SLC6A3 WILD-TYPE	87	137	184	88

'DSP MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S621. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
DSP MUTATED	3	0	2	3
DSP WILD-TYPE	66	43	72	51

'DSP MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.962 (Fisher's exact test), Q value = 1

Table S622. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
DSP MUTATED	2	1	2	3
DSP WILD-TYPE	61	49	46	76

'DSP MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S623. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
DSP MUTATED	3	5	3	1
DSP WILD-TYPE	74	88	42	59

'DSP MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0719 (Fisher's exact test), Q value = 0.51

Table S624. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
DSP MUTATED	6	0	6
DSP WILD-TYPE	132	61	70

'DSP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0708 (Fisher's exact test), Q value = 0.51

Table S625. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
DSP MUTATED	13	8	0
DSP WILD-TYPE	282	473	7

'DSP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0453 (Fisher's exact test), Q value = 0.41

Table S626. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
DSP MUTATED	9	3	1	2
DSP WILD-TYPE	151	229	63	164

Figure S173. Get High-res Image Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'DSP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S627. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
DSP MUTATED	6	2	6
DSP WILD-TYPE	189	184	183

'DSP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S628. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
DSP MUTATED	5	7	2
DSP WILD-TYPE	199	212	145

'DSP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S629. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
DSP MUTATED	5	3	2
DSP WILD-TYPE	222	232	190

'DSP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.728 (Fisher's exact test), Q value = 1

Table S630. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
DSP MUTATED	4	3	3
DSP WILD-TYPE	192	187	265

'DSP MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.712 (Fisher's exact test), Q value = 1

Table S631. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DSP MUTATED	3	3	2	1
DSP WILD-TYPE	133	104	181	82

'DSP MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0163 (Fisher's exact test), Q value = 0.22

Table S632. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DSP MUTATED	5	0	4
DSP WILD-TYPE	217	184	99

Figure S174. Get High-res Image Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'DSP MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S633. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DSP MUTATED	4	3	2
DSP WILD-TYPE	180	159	157

'DSP MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.55 (Fisher's exact test), Q value = 1

Table S634. Gene #52: 'DSP MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DSP MUTATED	2	2	2	3
DSP WILD-TYPE	88	136	186	86

'ZNF292 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S635. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
ZNF292 MUTATED	0	0	2	1
ZNF292 WILD-TYPE	69	43	72	53

'ZNF292 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.223 (Fisher's exact test), Q value = 0.88

Table S636. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ZNF292 MUTATED	0	0	2	1
ZNF292 WILD-TYPE	63	50	46	78

'ZNF292 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S637. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
ZNF292 MUTATED	0	2	1	0
ZNF292 WILD-TYPE	77	91	44	60

'ZNF292 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.98

Table S638. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ZNF292 MUTATED	1	0	2
ZNF292 WILD-TYPE	137	61	74

'ZNF292 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.94

Table S639. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZNF292 MUTATED	3	14	0
ZNF292 WILD-TYPE	292	467	7

'ZNF292 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 0.81

Table S640. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZNF292 MUTATED	2	4	1	8
ZNF292 WILD-TYPE	158	228	63	158

'ZNF292 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S641. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZNF292 MUTATED	3	7	5
ZNF292 WILD-TYPE	192	179	184

'ZNF292 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S642. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZNF292 MUTATED	5	5	5
ZNF292 WILD-TYPE	199	214	142

'ZNF292 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.156 (Fisher's exact test), Q value = 0.79

Table S643. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZNF292 MUTATED	3	4	8
ZNF292 WILD-TYPE	224	231	184

'ZNF292 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0867 (Fisher's exact test), Q value = 0.58

Table S644. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZNF292 MUTATED	1	5	9
ZNF292 WILD-TYPE	195	185	259

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.426 (Fisher's exact test), Q value = 1

Table S645. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF292 MUTATED	2	3	8	1
ZNF292 WILD-TYPE	134	104	175	82

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.293 (Fisher's exact test), Q value = 0.97

Table S646. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF292 MUTATED	4	8	2
ZNF292 WILD-TYPE	218	176	101

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0837 (Fisher's exact test), Q value = 0.57

Table S647. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF292 MUTATED	2	4	8
ZNF292 WILD-TYPE	182	158	151

'ZNF292 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0543 (Fisher's exact test), Q value = 0.43

Table S648. Gene #53: 'ZNF292 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF292 MUTATED	0	3	10	1
ZNF292 WILD-TYPE	90	135	178	88

'KTELC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.85

Table S649. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KTELC1 MUTATED	0	5	0
KTELC1 WILD-TYPE	295	476	7

'KTELC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.97

Table S650. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KTELC1 MUTATED	0	4	0	1
KTELC1 WILD-TYPE	160	228	64	165

'KTELC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S651. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
KTELC1 MUTATED	2	1	1
KTELC1 WILD-TYPE	193	185	188

'KTELC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S652. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
KTELC1 MUTATED	3	1	0
KTELC1 WILD-TYPE	201	218	147

'KTELC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S653. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KTELC1 MUTATED	1	3	1
KTELC1 WILD-TYPE	226	232	191

'KTELC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S654. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KTELC1 MUTATED	0	3	2
KTELC1 WILD-TYPE	196	187	266

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.67

Table S655. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KTELC1 MUTATED	0	3	1	1
KTELC1 WILD-TYPE	136	104	182	82

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00699 (Fisher's exact test), Q value = 0.13

Table S656. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KTELC1 MUTATED	1	0	4
KTELC1 WILD-TYPE	221	184	99

Figure S175. Get High-res Image Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S657. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KTELC1 MUTATED	2	2	1
KTELC1 WILD-TYPE	182	160	158

'KTELC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.109 (Fisher's exact test), Q value = 0.65

Table S658. Gene #54: 'KTELC1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KTELC1 MUTATED	0	4	1	0
KTELC1 WILD-TYPE	90	134	187	89

'TLR6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.247 (Fisher's exact test), Q value = 0.93

Table S659. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TLR6 MUTATED	0	0	3	1
TLR6 WILD-TYPE	69	43	71	53

'TLR6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0479 (Fisher's exact test), Q value = 0.42

Table S660. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TLR6 MUTATED	0	0	3	1
TLR6 WILD-TYPE	63	50	45	78

Figure S176. Get High-res Image Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'TLR6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S661. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TLR6 MUTATED	0	2	1	2
TLR6 WILD-TYPE	77	91	44	58

'TLR6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.294 (Fisher's exact test), Q value = 0.97

Table S662. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TLR6 MUTATED	1	2	2
TLR6 WILD-TYPE	137	59	74

'TLR6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.69

Table S663. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TLR6 MUTATED	6	2	0
TLR6 WILD-TYPE	289	479	7

'TLR6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00824 (Fisher's exact test), Q value = 0.14

Table S664. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TLR6 MUTATED	2	0	2	0
TLR6 WILD-TYPE	158	232	62	166

Figure S177. Get High-res Image Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TLR6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S665. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TLR6 MUTATED	2	1	1
TLR6 WILD-TYPE	193	185	188

'TLR6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S666. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TLR6 MUTATED	1	2	1
TLR6 WILD-TYPE	203	217	146

'TLR6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S667. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TLR6 MUTATED	2	0	2
TLR6 WILD-TYPE	225	235	190

'TLR6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S668. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TLR6 MUTATED	2	0	2
TLR6 WILD-TYPE	194	190	266

'TLR6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.95

Table S669. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TLR6 MUTATED	0	0	3	0
TLR6 WILD-TYPE	136	107	180	83

'TLR6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 0.9

Table S670. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TLR6 MUTATED	0	2	1
TLR6 WILD-TYPE	222	182	102

'TLR6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S671. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TLR6 MUTATED	1	0	2
TLR6 WILD-TYPE	183	162	157

'TLR6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S672. Gene #55: 'TLR6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TLR6 MUTATED	0	0	2	1
TLR6 WILD-TYPE	90	138	186	88

'EGFR MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.00713 (Fisher's exact test), Q value = 0.13

Table S673. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
EGFR MUTATED	20	7	31	10
EGFR WILD-TYPE	49	36	43	44

Figure S178. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'EGFR MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0563 (Fisher's exact test), Q value = 0.45

Table S674. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
EGFR MUTATED	18	7	17	26
EGFR WILD-TYPE	45	43	31	53

'EGFR MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.51 (Fisher's exact test), Q value = 1

Table S675. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
EGFR MUTATED	22	27	8	17
EGFR WILD-TYPE	55	66	37	43

'EGFR MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.14 (Fisher's exact test), Q value = 0.74

Table S676. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
EGFR MUTATED	30	19	25
EGFR WILD-TYPE	108	42	51

'EGFR MUTATION STATUS' versus 'CN_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S677. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
EGFR MUTATED	95	11	1
EGFR WILD-TYPE	200	470	6

Figure S179. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'EGFR MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S678. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
EGFR MUTATED	47	0	6	3
EGFR WILD-TYPE	113	232	58	163

Figure S180. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'EGFR MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0725 (Fisher's exact test), Q value = 0.51

Table S679. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
EGFR MUTATED	26	13	25
EGFR WILD-TYPE	169	173	164

'EGFR MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0196 (Fisher's exact test), Q value = 0.25

Table S680. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
EGFR MUTATED	18	35	11
EGFR WILD-TYPE	186	184	136

Figure S181. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S681. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
EGFR MUTATED	71	0	9
EGFR WILD-TYPE	156	235	183

Figure S182. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'EGFR MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S682. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
EGFR MUTATED	69	2	9
EGFR WILD-TYPE	127	188	259

Figure S183. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0107 (Fisher's exact test), Q value = 0.17

Table S683. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
EGFR MUTATED	11	11	13	0
EGFR WILD-TYPE	125	96	170	83

Figure S184. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'EGFR MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S684. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
EGFR MUTATED	1	9	25
EGFR WILD-TYPE	221	175	78

Figure S185. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'EGFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S685. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
EGFR MUTATED	23	0	12
EGFR WILD-TYPE	161	162	147

Figure S186. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'EGFR MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1e-05 (Fisher's exact test), Q value = 0.00041

Table S686. Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
EGFR MUTATED	0	0	8	27
EGFR WILD-TYPE	90	138	180	62

Figure S187. Get High-res Image Gene #56: 'EGFR MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ACADS MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.416 (Fisher's exact test), Q value = 1

Table S687. Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
ACADS MUTATED	2	0	0	1
ACADS WILD-TYPE	67	43	74	53

'ACADS MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.35 (Fisher's exact test), Q value = 1

Table S688. Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ACADS MUTATED	2	1	0	0
ACADS WILD-TYPE	61	49	48	79

'ACADS MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S689. Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
ACADS MUTATED	2	0	0	1
ACADS WILD-TYPE	75	93	45	59

'ACADS MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S690. Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ACADS MUTATED	1	1	1
ACADS WILD-TYPE	137	60	75

'ACADS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00812 (Fisher's exact test), Q value = 0.14

Table S691. Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ACADS MUTATED	3	1	1
ACADS WILD-TYPE	292	480	6

Figure S188. Get High-res Image Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ACADS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0464 (Fisher's exact test), Q value = 0.41

Table S692. Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ACADS MUTATED	3	0	0	0
ACADS WILD-TYPE	157	232	64	166

Figure S189. Get High-res Image Gene #57: 'ACADS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TMEM216 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 0.98

Table S693. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TMEM216 MUTATED	0	3	0
TMEM216 WILD-TYPE	295	478	7

'TMEM216 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.844 (Fisher's exact test), Q value = 1

Table S694. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TMEM216 MUTATED	0	2	0	1
TMEM216 WILD-TYPE	160	230	64	165

'TMEM216 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S695. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TMEM216 MUTATED	1	2	0
TMEM216 WILD-TYPE	194	184	189

'TMEM216 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 0.85

Table S696. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TMEM216 MUTATED	1	0	2
TMEM216 WILD-TYPE	203	219	145

'TMEM216 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.97

Table S697. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TMEM216 MUTATED	0	1	2
TMEM216 WILD-TYPE	227	234	190

'TMEM216 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S698. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TMEM216 MUTATED	0	1	2
TMEM216 WILD-TYPE	196	189	266

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S699. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TMEM216 MUTATED	0	1	1	1
TMEM216 WILD-TYPE	136	106	182	82

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S700. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TMEM216 MUTATED	1	2	0
TMEM216 WILD-TYPE	221	182	103

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.98

Table S701. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TMEM216 MUTATED	0	2	1
TMEM216 WILD-TYPE	184	160	158

'TMEM216 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S702. Gene #58: 'TMEM216 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TMEM216 MUTATED	0	2	1	0
TMEM216 WILD-TYPE	90	136	187	89

'ARID2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S703. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ARID2 MUTATED	3	10	0
ARID2 WILD-TYPE	292	471	7

'ARID2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S704. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ARID2 MUTATED	3	5	1	2
ARID2 WILD-TYPE	157	227	63	164

'ARID2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S705. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ARID2 MUTATED	3	2	3
ARID2 WILD-TYPE	192	184	186

'ARID2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.61 (Fisher's exact test), Q value = 1

Table S706. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ARID2 MUTATED	4	3	1
ARID2 WILD-TYPE	200	216	146

'ARID2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S707. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ARID2 MUTATED	4	4	4
ARID2 WILD-TYPE	223	231	188

'ARID2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.145 (Fisher's exact test), Q value = 0.76

Table S708. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ARID2 MUTATED	1	6	5
ARID2 WILD-TYPE	195	184	263

'ARID2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S709. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ARID2 MUTATED	2	4	3	1
ARID2 WILD-TYPE	134	103	180	82

'ARID2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.343 (Fisher's exact test), Q value = 1

Table S710. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ARID2 MUTATED	3	3	4
ARID2 WILD-TYPE	219	181	99

'ARID2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S711. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ARID2 MUTATED	3	2	5
ARID2 WILD-TYPE	181	160	154

'ARID2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S712. Gene #59: 'ARID2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ARID2 MUTATED	1	1	5	3
ARID2 WILD-TYPE	89	137	183	86

'FAM83D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S713. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
FAM83D MUTATED	3	2	0
FAM83D WILD-TYPE	292	479	7

'FAM83D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S714. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
FAM83D MUTATED	3	1	0	1
FAM83D WILD-TYPE	157	231	64	165

'FAM83D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.215 (Fisher's exact test), Q value = 0.87

Table S715. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
FAM83D MUTATED	0	2	1
FAM83D WILD-TYPE	195	184	188

'FAM83D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S716. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
FAM83D MUTATED	1	2	0
FAM83D WILD-TYPE	203	217	147

'FAM83D MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.843 (Fisher's exact test), Q value = 1

Table S717. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
FAM83D MUTATED	2	1	1
FAM83D WILD-TYPE	225	234	191

'FAM83D MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S718. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
FAM83D MUTATED	2	1	1
FAM83D WILD-TYPE	194	189	267

'FAM83D MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S719. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FAM83D MUTATED	1	1	1	0
FAM83D WILD-TYPE	135	106	182	83

'FAM83D MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0533 (Fisher's exact test), Q value = 0.43

Table S720. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FAM83D MUTATED	0	1	2
FAM83D WILD-TYPE	222	183	101

'FAM83D MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S721. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FAM83D MUTATED	1	1	1
FAM83D WILD-TYPE	183	161	158

'FAM83D MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S722. Gene #60: 'FAM83D MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FAM83D MUTATED	0	1	1	1
FAM83D WILD-TYPE	90	137	187	88

'NEU2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 0.88

Table S723. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
NEU2 MUTATED	1	0	0	2
NEU2 WILD-TYPE	68	43	74	52

'NEU2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S724. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
NEU2 MUTATED	0	1	0	2
NEU2 WILD-TYPE	63	49	48	77

'NEU2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S725. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
NEU2 MUTATED	1	1	1	0
NEU2 WILD-TYPE	76	92	44	60

'NEU2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S726. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
NEU2 MUTATED	2	0	1
NEU2 WILD-TYPE	136	61	75

'NEU2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S727. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NEU2 MUTATED	3	5	0
NEU2 WILD-TYPE	292	476	7

'NEU2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S728. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NEU2 MUTATED	1	3	0	1
NEU2 WILD-TYPE	159	229	64	165

'NEU2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0897 (Fisher's exact test), Q value = 0.59

Table S729. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NEU2 MUTATED	0	2	4
NEU2 WILD-TYPE	195	184	185

'NEU2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.171 (Fisher's exact test), Q value = 0.81

Table S730. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NEU2 MUTATED	0	4	2
NEU2 WILD-TYPE	204	215	145

'NEU2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S731. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NEU2 MUTATED	2	3	2
NEU2 WILD-TYPE	225	232	190

'NEU2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.346 (Fisher's exact test), Q value = 1

Table S732. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NEU2 MUTATED	3	3	1
NEU2 WILD-TYPE	193	187	267

'NEU2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.305 (Fisher's exact test), Q value = 0.98

Table S733. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NEU2 MUTATED	0	1	2	2
NEU2 WILD-TYPE	136	106	181	81

'NEU2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S734. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NEU2 MUTATED	2	2	1
NEU2 WILD-TYPE	220	182	102

'NEU2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S735. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NEU2 MUTATED	1	1	3
NEU2 WILD-TYPE	183	161	156

'NEU2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S736. Gene #61: 'NEU2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NEU2 MUTATED	0	1	3	1
NEU2 WILD-TYPE	90	137	185	88

'LUM MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S737. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
LUM MUTATED	1	0	2	0
LUM WILD-TYPE	68	43	72	54

'LUM MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.117 (Fisher's exact test), Q value = 0.67

Table S738. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
LUM MUTATED	1	0	2	0
LUM WILD-TYPE	62	50	46	79

'LUM MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S739. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
LUM MUTATED	1	1	1	2
LUM WILD-TYPE	76	92	44	58

'LUM MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.713 (Fisher's exact test), Q value = 1

Table S740. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
LUM MUTATED	2	2	1
LUM WILD-TYPE	136	59	75

'LUM MUTATION STATUS' versus 'CN_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 0.81

Table S741. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
LUM MUTATED	5	2	0
LUM WILD-TYPE	290	479	7

'LUM MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.312 (Fisher's exact test), Q value = 0.98

Table S742. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
LUM MUTATED	2	1	1	0
LUM WILD-TYPE	158	231	63	166

'LUM MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S743. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
LUM MUTATED	1	2	1
LUM WILD-TYPE	194	184	188

'LUM MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S744. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
LUM MUTATED	1	2	1
LUM WILD-TYPE	203	217	146

'LUM MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S745. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
LUM MUTATED	2	0	1
LUM WILD-TYPE	225	235	191

'LUM MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S746. Gene #62: 'LUM MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
LUM MUTATED	1	1	1
LUM WILD-TYPE	195	189	267

'WRN MUTATION STATUS' versus 'CN_CNMF'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S747. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
WRN MUTATED	1	5	0
WRN WILD-TYPE	294	476	7

'WRN MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0487 (Fisher's exact test), Q value = 0.42

Table S748. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
WRN MUTATED	1	0	0	4
WRN WILD-TYPE	159	232	64	162

Figure S190. Get High-res Image Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'WRN MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S749. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
WRN MUTATED	2	2	1
WRN WILD-TYPE	193	184	188

'WRN MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S750. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
WRN MUTATED	2	1	2
WRN WILD-TYPE	202	218	145

'WRN MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S751. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
WRN MUTATED	2	2	2
WRN WILD-TYPE	225	233	190

'WRN MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.518 (Fisher's exact test), Q value = 1

Table S752. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
WRN MUTATED	1	1	4
WRN WILD-TYPE	195	189	264

'WRN MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0566 (Fisher's exact test), Q value = 0.45

Table S753. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
WRN MUTATED	0	1	1	3
WRN WILD-TYPE	136	106	182	80

'WRN MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S754. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
WRN MUTATED	2	2	1
WRN WILD-TYPE	220	182	102

'WRN MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0447 (Fisher's exact test), Q value = 0.41

Table S755. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
WRN MUTATED	0	4	1
WRN WILD-TYPE	184	158	158

Figure S191. Get High-res Image Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'WRN MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.453 (Fisher's exact test), Q value = 1

Table S756. Gene #63: 'WRN MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
WRN MUTATED	0	3	2	0
WRN WILD-TYPE	90	135	186	89

'TMEM184A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S757. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TMEM184A MUTATED	1	2	0
TMEM184A WILD-TYPE	294	479	7

'TMEM184A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S758. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TMEM184A MUTATED	1	0	0	2
TMEM184A WILD-TYPE	159	232	64	164

'TMEM184A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S759. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TMEM184A MUTATED	1	1	1
TMEM184A WILD-TYPE	194	185	188

'TMEM184A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S760. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TMEM184A MUTATED	1	2	0
TMEM184A WILD-TYPE	203	217	147

'TMEM184A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.202 (Fisher's exact test), Q value = 0.85

Table S761. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TMEM184A MUTATED	1	0	2
TMEM184A WILD-TYPE	226	235	190

'TMEM184A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S762. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TMEM184A MUTATED	1	0	2
TMEM184A WILD-TYPE	195	190	266

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.88 (Fisher's exact test), Q value = 1

Table S763. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TMEM184A MUTATED	1	0	2	0
TMEM184A WILD-TYPE	135	107	181	83

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.232 (Fisher's exact test), Q value = 0.9

Table S764. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TMEM184A MUTATED	0	2	1
TMEM184A WILD-TYPE	222	182	102

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S765. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TMEM184A MUTATED	1	0	2
TMEM184A WILD-TYPE	183	162	157

'TMEM184A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S766. Gene #64: 'TMEM184A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TMEM184A MUTATED	0	0	2	1
TMEM184A WILD-TYPE	90	138	186	88

'ZNF512B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.85

Table S767. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZNF512B MUTATED	0	5	0
ZNF512B WILD-TYPE	295	476	7

'ZNF512B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.85 (Fisher's exact test), Q value = 1

Table S768. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZNF512B MUTATED	1	3	0	1
ZNF512B WILD-TYPE	159	229	64	165

'ZNF512B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S769. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZNF512B MUTATED	2	1	2
ZNF512B WILD-TYPE	193	185	187

'ZNF512B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S770. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZNF512B MUTATED	2	2	1
ZNF512B WILD-TYPE	202	217	146

'ZNF512B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S771. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZNF512B MUTATED	1	2	2
ZNF512B WILD-TYPE	226	233	190

'ZNF512B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S772. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZNF512B MUTATED	0	2	3
ZNF512B WILD-TYPE	196	188	265

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S773. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF512B MUTATED	1	1	2	1
ZNF512B WILD-TYPE	135	106	181	82

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S774. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF512B MUTATED	2	2	1
ZNF512B WILD-TYPE	220	182	102

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S775. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF512B MUTATED	1	1	3
ZNF512B WILD-TYPE	183	161	156

'ZNF512B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.245 (Fisher's exact test), Q value = 0.93

Table S776. Gene #65: 'ZNF512B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF512B MUTATED	1	0	4	0
ZNF512B WILD-TYPE	89	138	184	89

'PRCP MUTATION STATUS' versus 'CN_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.85

Table S777. Gene #66: 'PRCP MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PRCP MUTATED	3	1	0
PRCP WILD-TYPE	292	480	7

'PRCP MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0466 (Fisher's exact test), Q value = 0.41

Table S778. Gene #66: 'PRCP MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PRCP MUTATED	3	0	0	0
PRCP WILD-TYPE	157	232	64	166

Figure S192. Get High-res Image Gene #66: 'PRCP MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PRCP MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.661 (Fisher's exact test), Q value = 1

Table S779. Gene #66: 'PRCP MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PRCP MUTATED	2	1	0
PRCP WILD-TYPE	193	185	189

'PRCP MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.268 (Fisher's exact test), Q value = 0.95

Table S780. Gene #66: 'PRCP MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PRCP MUTATED	0	1	2
PRCP WILD-TYPE	204	218	145

'PRCP MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S781. Gene #66: 'PRCP MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PRCP MUTATED	2	0	1
PRCP WILD-TYPE	225	235	191

'PRCP MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.49 (Fisher's exact test), Q value = 1

Table S782. Gene #66: 'PRCP MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PRCP MUTATED	2	0	1
PRCP WILD-TYPE	194	190	267

'ATF7IP2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S783. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
ATF7IP2 MUTATED	1	0	2	1
ATF7IP2 WILD-TYPE	68	43	72	53

'ATF7IP2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S784. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ATF7IP2 MUTATED	1	1	1	1
ATF7IP2 WILD-TYPE	62	49	47	78

'ATF7IP2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.285 (Fisher's exact test), Q value = 0.97

Table S785. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
ATF7IP2 MUTATED	1	1	0	3
ATF7IP2 WILD-TYPE	76	92	45	57

'ATF7IP2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.106 (Fisher's exact test), Q value = 0.65

Table S786. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ATF7IP2 MUTATED	1	3	1
ATF7IP2 WILD-TYPE	137	58	75

'ATF7IP2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00339 (Fisher's exact test), Q value = 0.072

Table S787. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ATF7IP2 MUTATED	6	1	1
ATF7IP2 WILD-TYPE	289	480	6

Figure S193. Get High-res Image Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ATF7IP2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.316 (Fisher's exact test), Q value = 0.99

Table S788. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ATF7IP2 MUTATED	2	1	1	0
ATF7IP2 WILD-TYPE	158	231	63	166

'ATF7IP2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S789. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ATF7IP2 MUTATED	2	2	1
ATF7IP2 WILD-TYPE	193	184	188

'ATF7IP2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S790. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ATF7IP2 MUTATED	2	2	1
ATF7IP2 WILD-TYPE	202	217	146

'ATF7IP2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0222 (Fisher's exact test), Q value = 0.26

Table S791. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ATF7IP2 MUTATED	4	0	0
ATF7IP2 WILD-TYPE	223	235	192

Figure S194. Get High-res Image Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ATF7IP2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.103 (Fisher's exact test), Q value = 0.64

Table S792. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ATF7IP2 MUTATED	3	1	0
ATF7IP2 WILD-TYPE	193	189	268

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S793. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ATF7IP2 MUTATED	1	1	1	0
ATF7IP2 WILD-TYPE	135	106	182	83

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00849 (Fisher's exact test), Q value = 0.14

Table S794. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ATF7IP2 MUTATED	0	0	3
ATF7IP2 WILD-TYPE	222	184	100

Figure S195. Get High-res Image Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S795. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ATF7IP2 MUTATED	2	0	1
ATF7IP2 WILD-TYPE	182	162	158

'ATF7IP2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0886 (Fisher's exact test), Q value = 0.59

Table S796. Gene #67: 'ATF7IP2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ATF7IP2 MUTATED	0	1	0	2
ATF7IP2 WILD-TYPE	90	137	188	87

'DNMT3A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0317 (Fisher's exact test), Q value = 0.32

Table S797. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
DNMT3A MUTATED	0	10	0
DNMT3A WILD-TYPE	295	471	7

Figure S196. Get High-res Image Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'DNMT3A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S798. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
DNMT3A MUTATED	2	4	1	3
DNMT3A WILD-TYPE	158	228	63	163

'DNMT3A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.119 (Fisher's exact test), Q value = 0.67

Table S799. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
DNMT3A MUTATED	3	4	0
DNMT3A WILD-TYPE	192	182	189

'DNMT3A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S800. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
DNMT3A MUTATED	3	1	3
DNMT3A WILD-TYPE	201	218	144

'DNMT3A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.88

Table S801. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
DNMT3A MUTATED	1	5	4
DNMT3A WILD-TYPE	226	230	188

'DNMT3A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0859 (Fisher's exact test), Q value = 0.58

Table S802. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
DNMT3A MUTATED	0	4	6
DNMT3A WILD-TYPE	196	186	262

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S803. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DNMT3A MUTATED	1	2	6	1
DNMT3A WILD-TYPE	135	105	177	82

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.045 (Fisher's exact test), Q value = 0.41

Table S804. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DNMT3A MUTATED	1	5	4
DNMT3A WILD-TYPE	221	179	99

Figure S197. Get High-res Image Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S805. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DNMT3A MUTATED	3	4	3
DNMT3A WILD-TYPE	181	158	156

'DNMT3A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.972 (Fisher's exact test), Q value = 1

Table S806. Gene #68: 'DNMT3A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DNMT3A MUTATED	1	3	4	2
DNMT3A WILD-TYPE	89	135	184	87

'PROKR2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.602 (Fisher's exact test), Q value = 1

Table S807. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PROKR2 MUTATED	1	0	3	1
PROKR2 WILD-TYPE	68	43	71	53

'PROKR2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S808. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PROKR2 MUTATED	1	1	2	1
PROKR2 WILD-TYPE	62	49	46	78

'PROKR2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.719 (Fisher's exact test), Q value = 1

Table S809. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PROKR2 MUTATED	1	1	1	2
PROKR2 WILD-TYPE	76	92	44	58

'PROKR2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.184 (Fisher's exact test), Q value = 0.85

Table S810. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PROKR2 MUTATED	1	1	3
PROKR2 WILD-TYPE	137	60	73

'PROKR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0517 (Fisher's exact test), Q value = 0.43

Table S811. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PROKR2 MUTATED	7	2	0
PROKR2 WILD-TYPE	288	479	7

'PROKR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.94

Table S812. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PROKR2 MUTATED	3	2	0	0
PROKR2 WILD-TYPE	157	230	64	166

'PROKR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.321 (Fisher's exact test), Q value = 1

Table S813. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PROKR2 MUTATED	0	1	2
PROKR2 WILD-TYPE	195	185	187

'PROKR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.483 (Fisher's exact test), Q value = 1

Table S814. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PROKR2 MUTATED	0	2	1
PROKR2 WILD-TYPE	204	217	146

'PROKR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0904 (Fisher's exact test), Q value = 0.59

Table S815. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PROKR2 MUTATED	6	1	1
PROKR2 WILD-TYPE	221	234	191

'PROKR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0401 (Fisher's exact test), Q value = 0.38

Table S816. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PROKR2 MUTATED	6	1	1
PROKR2 WILD-TYPE	190	189	267

Figure S198. Get High-res Image Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.281 (Fisher's exact test), Q value = 0.96

Table S817. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PROKR2 MUTATED	0	0	3	0
PROKR2 WILD-TYPE	136	107	180	83

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S818. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PROKR2 MUTATED	1	1	1
PROKR2 WILD-TYPE	221	183	102

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S819. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PROKR2 MUTATED	1	1	1
PROKR2 WILD-TYPE	183	161	158

'PROKR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S820. Gene #69: 'PROKR2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PROKR2 MUTATED	0	1	1	1
PROKR2 WILD-TYPE	90	137	187	88

'C10ORF76 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S821. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
C10ORF76 MUTATED	2	2	0
C10ORF76 WILD-TYPE	293	479	7

'C10ORF76 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0949 (Fisher's exact test), Q value = 0.6

Table S822. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
C10ORF76 MUTATED	3	0	0	1
C10ORF76 WILD-TYPE	157	232	64	165

'C10ORF76 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.79

Table S823. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
C10ORF76 MUTATED	3	0	1
C10ORF76 WILD-TYPE	224	235	191

'C10ORF76 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S824. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
C10ORF76 MUTATED	2	1	1
C10ORF76 WILD-TYPE	194	189	267

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S825. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
C10ORF76 MUTATED	0	2	1	0
C10ORF76 WILD-TYPE	136	105	182	83

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0515 (Fisher's exact test), Q value = 0.43

Table S826. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
C10ORF76 MUTATED	0	1	2
C10ORF76 WILD-TYPE	222	183	101

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S827. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
C10ORF76 MUTATED	1	0	2
C10ORF76 WILD-TYPE	183	162	157

'C10ORF76 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.511 (Fisher's exact test), Q value = 1

Table S828. Gene #70: 'C10ORF76 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
C10ORF76 MUTATED	0	0	2	1
C10ORF76 WILD-TYPE	90	138	186	88

'ZBTB20 MUTATION STATUS' versus 'CN_CNMF'

P value = 7e-05 (Fisher's exact test), Q value = 0.0023

Table S829. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZBTB20 MUTATED	0	22	0
ZBTB20 WILD-TYPE	295	459	7

Figure S199. Get High-res Image Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'ZBTB20 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 3e-05 (Fisher's exact test), Q value = 0.0011

Table S830. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZBTB20 MUTATED	2	3	0	16
ZBTB20 WILD-TYPE	158	229	64	150

Figure S200. Get High-res Image Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ZBTB20 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0843 (Fisher's exact test), Q value = 0.57

Table S831. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZBTB20 MUTATED	5	9	2
ZBTB20 WILD-TYPE	190	177	187

'ZBTB20 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0931 (Fisher's exact test), Q value = 0.59

Table S832. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZBTB20 MUTATED	3	5	8
ZBTB20 WILD-TYPE	201	214	139

'ZBTB20 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 9e-05 (Fisher's exact test), Q value = 0.0028

Table S833. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZBTB20 MUTATED	3	3	16
ZBTB20 WILD-TYPE	224	232	176

Figure S201. Get High-res Image Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'ZBTB20 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 4e-05 (Fisher's exact test), Q value = 0.0014

Table S834. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZBTB20 MUTATED	0	3	19
ZBTB20 WILD-TYPE	196	187	249

Figure S202. Get High-res Image Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.79

Table S835. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZBTB20 MUTATED	3	2	12	4
ZBTB20 WILD-TYPE	133	105	171	79

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0204 (Fisher's exact test), Q value = 0.25

Table S836. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZBTB20 MUTATED	5	14	2
ZBTB20 WILD-TYPE	217	170	101

Figure S203. Get High-res Image Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0411 (Fisher's exact test), Q value = 0.39

Table S837. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZBTB20 MUTATED	3	7	11
ZBTB20 WILD-TYPE	181	155	148

Figure S204. Get High-res Image Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'ZBTB20 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0317 (Fisher's exact test), Q value = 0.32

Table S838. Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZBTB20 MUTATED	1	5	14	1
ZBTB20 WILD-TYPE	89	133	174	88

Figure S205. Get High-res Image Gene #71: 'ZBTB20 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'KRT15 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S839. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KRT15 MUTATED	2	6	0
KRT15 WILD-TYPE	293	475	7

'KRT15 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.485 (Fisher's exact test), Q value = 1

Table S840. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KRT15 MUTATED	0	3	1	2
KRT15 WILD-TYPE	160	229	63	164

'KRT15 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.846 (Fisher's exact test), Q value = 1

Table S841. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
KRT15 MUTATED	1	1	2
KRT15 WILD-TYPE	194	185	187

'KRT15 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S842. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
KRT15 MUTATED	2	1	1
KRT15 WILD-TYPE	202	218	146

'KRT15 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S843. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KRT15 MUTATED	3	1	3
KRT15 WILD-TYPE	224	234	189

'KRT15 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S844. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KRT15 MUTATED	2	2	3
KRT15 WILD-TYPE	194	188	265

'KRT15 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S845. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KRT15 MUTATED	3	0	2	1
KRT15 WILD-TYPE	133	107	181	82

'KRT15 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.866 (Fisher's exact test), Q value = 1

Table S846. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KRT15 MUTATED	2	3	1
KRT15 WILD-TYPE	220	181	102

'KRT15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S847. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KRT15 MUTATED	2	2	2
KRT15 WILD-TYPE	182	160	157

'KRT15 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S848. Gene #72: 'KRT15 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KRT15 MUTATED	1	2	2	1
KRT15 WILD-TYPE	89	136	186	88

'G6PC MUTATION STATUS' versus 'CN_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S849. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
G6PC MUTATED	2	5	0
G6PC WILD-TYPE	293	476	7

'G6PC MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.95

Table S850. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
G6PC MUTATED	4	1	0	2
G6PC WILD-TYPE	156	231	64	164

'G6PC MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.322 (Fisher's exact test), Q value = 1

Table S851. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
G6PC MUTATED	2	4	1
G6PC WILD-TYPE	193	182	188

'G6PC MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S852. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
G6PC MUTATED	3	3	1
G6PC WILD-TYPE	201	216	146

'G6PC MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.799 (Fisher's exact test), Q value = 1

Table S853. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
G6PC MUTATED	2	2	3
G6PC WILD-TYPE	225	233	189

'G6PC MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S854. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
G6PC MUTATED	2	2	3
G6PC WILD-TYPE	194	188	265

'G6PC MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.428 (Fisher's exact test), Q value = 1

Table S855. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
G6PC MUTATED	0	2	3	1
G6PC WILD-TYPE	136	105	180	82

'G6PC MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.15 (Fisher's exact test), Q value = 0.78

Table S856. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
G6PC MUTATED	1	2	3
G6PC WILD-TYPE	221	182	100

'G6PC MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.294 (Fisher's exact test), Q value = 0.97

Table S857. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
G6PC MUTATED	1	1	4
G6PC WILD-TYPE	183	161	155

'G6PC MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S858. Gene #73: 'G6PC MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
G6PC MUTATED	1	1	2	2
G6PC WILD-TYPE	89	137	186	87

'SERPING1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S859. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SERPING1 MUTATED	2	2	0
SERPING1 WILD-TYPE	293	479	7

'SERPING1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S860. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SERPING1 MUTATED	2	1	0	1
SERPING1 WILD-TYPE	158	231	64	165

'SERPING1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S861. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SERPING1 MUTATED	2	1	1
SERPING1 WILD-TYPE	193	185	188

'SERPING1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.14 (Fisher's exact test), Q value = 0.74

Table S862. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SERPING1 MUTATED	3	0	1
SERPING1 WILD-TYPE	201	219	146

'SERPING1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.297 (Fisher's exact test), Q value = 0.97

Table S863. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SERPING1 MUTATED	0	1	2
SERPING1 WILD-TYPE	227	234	190

'SERPING1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S864. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SERPING1 MUTATED	0	1	2
SERPING1 WILD-TYPE	196	189	266

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S865. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SERPING1 MUTATED	0	1	2	0
SERPING1 WILD-TYPE	136	106	181	83

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S866. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SERPING1 MUTATED	1	2	0
SERPING1 WILD-TYPE	221	182	103

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S867. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SERPING1 MUTATED	1	0	2
SERPING1 WILD-TYPE	183	162	157

'SERPING1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.584 (Fisher's exact test), Q value = 1

Table S868. Gene #74: 'SERPING1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SERPING1 MUTATED	1	0	2	0
SERPING1 WILD-TYPE	89	138	186	89

'ZDHHC4 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 0.8

Table S869. Gene #75: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
ZDHHC4 MUTATED	0	3	0	0
ZDHHC4 WILD-TYPE	77	90	45	60

'ZDHHC4 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S870. Gene #75: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ZDHHC4 MUTATED	2	0	1
ZDHHC4 WILD-TYPE	136	61	75

'ZDHHC4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.184 (Fisher's exact test), Q value = 0.85

Table S871. Gene #75: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZDHHC4 MUTATED	3	1	0
ZDHHC4 WILD-TYPE	292	480	7

'ZDHHC4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0124 (Fisher's exact test), Q value = 0.19

Table S872. Gene #75: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZDHHC4 MUTATED	4	0	0	0
ZDHHC4 WILD-TYPE	156	232	64	166

Figure S206. Get High-res Image Gene #75: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ZDHHC4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S873. Gene #75: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZDHHC4 MUTATED	1	1	1
ZDHHC4 WILD-TYPE	194	185	188

'ZDHHC4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S874. Gene #75: 'ZDHHC4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZDHHC4 MUTATED	2	1	0
ZDHHC4 WILD-TYPE	202	218	147

'CPEB4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.31 (Fisher's exact test), Q value = 0.98

Table S875. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CPEB4 MUTATED	1	6	0
CPEB4 WILD-TYPE	294	475	7

'CPEB4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S876. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CPEB4 MUTATED	1	1	1	3
CPEB4 WILD-TYPE	159	231	63	163

'CPEB4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S877. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CPEB4 MUTATED	3	1	2
CPEB4 WILD-TYPE	192	185	187

'CPEB4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S878. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CPEB4 MUTATED	3	2	1
CPEB4 WILD-TYPE	201	217	146

'CPEB4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S879. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CPEB4 MUTATED	2	2	3
CPEB4 WILD-TYPE	225	233	189

'CPEB4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.577 (Fisher's exact test), Q value = 1

Table S880. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CPEB4 MUTATED	1	2	4
CPEB4 WILD-TYPE	195	188	264

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.767 (Fisher's exact test), Q value = 1

Table S881. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CPEB4 MUTATED	1	1	2	2
CPEB4 WILD-TYPE	135	106	181	81

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S882. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CPEB4 MUTATED	3	2	1
CPEB4 WILD-TYPE	219	182	102

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S883. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CPEB4 MUTATED	1	2	3
CPEB4 WILD-TYPE	183	160	156

'CPEB4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S884. Gene #76: 'CPEB4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CPEB4 MUTATED	0	3	3	0
CPEB4 WILD-TYPE	90	135	185	89

'EEF1A1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S885. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
EEF1A1 MUTATED	1	0	3	0
EEF1A1 WILD-TYPE	68	43	71	54

'EEF1A1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S886. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
EEF1A1 MUTATED	0	0	2	2
EEF1A1 WILD-TYPE	63	50	46	77

'EEF1A1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S887. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
EEF1A1 MUTATED	0	2	1	1
EEF1A1 WILD-TYPE	77	91	44	59

'EEF1A1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S888. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
EEF1A1 MUTATED	1	1	2
EEF1A1 WILD-TYPE	137	60	74

'EEF1A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.125 (Fisher's exact test), Q value = 0.69

Table S889. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
EEF1A1 MUTATED	6	2	0
EEF1A1 WILD-TYPE	289	479	7

'EEF1A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.476 (Fisher's exact test), Q value = 1

Table S890. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
EEF1A1 MUTATED	3	1	0	1
EEF1A1 WILD-TYPE	157	231	64	165

'EEF1A1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0373 (Fisher's exact test), Q value = 0.36

Table S891. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
EEF1A1 MUTATED	4	0	0
EEF1A1 WILD-TYPE	191	186	189

Figure S207. Get High-res Image Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'EEF1A1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S892. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
EEF1A1 MUTATED	2	2	0
EEF1A1 WILD-TYPE	202	217	147

'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 0.88

Table S893. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
EEF1A1 MUTATED	4	2	0
EEF1A1 WILD-TYPE	223	233	192

'EEF1A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S894. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
EEF1A1 MUTATED	3	2	1
EEF1A1 WILD-TYPE	193	188	267

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0219 (Fisher's exact test), Q value = 0.26

Table S895. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
EEF1A1 MUTATED	0	3	0	1
EEF1A1 WILD-TYPE	136	104	183	82

Figure S208. Get High-res Image Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S896. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
EEF1A1 MUTATED	2	0	2
EEF1A1 WILD-TYPE	220	184	101

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S897. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
EEF1A1 MUTATED	2	1	1
EEF1A1 WILD-TYPE	182	161	158

'EEF1A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S898. Gene #77: 'EEF1A1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
EEF1A1 MUTATED	1	1	1	1
EEF1A1 WILD-TYPE	89	137	187	88

'PDHA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S899. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PDHA1 MUTATED	2	4	0
PDHA1 WILD-TYPE	293	477	7

'PDHA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.544 (Fisher's exact test), Q value = 1

Table S900. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PDHA1 MUTATED	1	1	0	3
PDHA1 WILD-TYPE	159	231	64	163

'PDHA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S901. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PDHA1 MUTATED	3	1	2
PDHA1 WILD-TYPE	192	185	187

'PDHA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.301 (Fisher's exact test), Q value = 0.98

Table S902. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PDHA1 MUTATED	4	1	1
PDHA1 WILD-TYPE	200	218	146

'PDHA1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S903. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PDHA1 MUTATED	2	3	1
PDHA1 WILD-TYPE	225	232	191

'PDHA1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.883 (Fisher's exact test), Q value = 1

Table S904. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PDHA1 MUTATED	2	1	3
PDHA1 WILD-TYPE	194	189	265

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S905. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PDHA1 MUTATED	2	1	2	0
PDHA1 WILD-TYPE	134	106	181	83

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S906. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PDHA1 MUTATED	3	1	1
PDHA1 WILD-TYPE	219	183	102

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.533 (Fisher's exact test), Q value = 1

Table S907. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PDHA1 MUTATED	1	3	1
PDHA1 WILD-TYPE	183	159	158

'PDHA1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S908. Gene #78: 'PDHA1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PDHA1 MUTATED	0	3	1	1
PDHA1 WILD-TYPE	90	135	187	88

'FAM123C MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0233 (Fisher's exact test), Q value = 0.27

Table S909. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
FAM123C MUTATED	3	3	0	0
FAM123C WILD-TYPE	66	40	74	54

Figure S209. Get High-res Image Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

'FAM123C MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S910. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FAM123C MUTATED	3	1	0	2
FAM123C WILD-TYPE	60	49	48	77

'FAM123C MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.848 (Fisher's exact test), Q value = 1

Table S911. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
FAM123C MUTATED	2	3	0	1
FAM123C WILD-TYPE	75	90	45	59

'FAM123C MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.119 (Fisher's exact test), Q value = 0.67

Table S912. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FAM123C MUTATED	1	3	2
FAM123C WILD-TYPE	137	58	74

'FAM123C MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.85

Table S913. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
FAM123C MUTATED	7	4	0
FAM123C WILD-TYPE	288	477	7

'FAM123C MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.69

Table S914. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
FAM123C MUTATED	2	2	2	0
FAM123C WILD-TYPE	158	230	62	166

'FAM123C MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.71 (Fisher's exact test), Q value = 1

Table S915. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
FAM123C MUTATED	3	1	3
FAM123C WILD-TYPE	192	185	186

'FAM123C MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.95

Table S916. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
FAM123C MUTATED	4	3	0
FAM123C WILD-TYPE	200	216	147

'FAM123C MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.116 (Fisher's exact test), Q value = 0.67

Table S917. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
FAM123C MUTATED	5	3	0
FAM123C WILD-TYPE	222	232	192

'FAM123C MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.104 (Fisher's exact test), Q value = 0.64

Table S918. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
FAM123C MUTATED	5	2	1
FAM123C WILD-TYPE	191	188	267

'FAM123C MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0689 (Fisher's exact test), Q value = 0.5

Table S919. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FAM123C MUTATED	3	0	0	1
FAM123C WILD-TYPE	133	107	183	82

'FAM123C MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 0.95

Table S920. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FAM123C MUTATED	3	0	1
FAM123C WILD-TYPE	219	184	102

'FAM123C MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.396 (Fisher's exact test), Q value = 1

Table S921. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FAM123C MUTATED	3	1	0
FAM123C WILD-TYPE	181	161	159

'FAM123C MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.141 (Fisher's exact test), Q value = 0.75

Table S922. Gene #79: 'FAM123C MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FAM123C MUTATED	2	1	0	1
FAM123C WILD-TYPE	88	137	188	88

'KRAS MUTATION STATUS' versus 'CN_CNMF'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S923. Gene #80: 'KRAS MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KRAS MUTATED	2	2	0
KRAS WILD-TYPE	293	479	7

'KRAS MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S924. Gene #80: 'KRAS MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KRAS MUTATED	1	1	0	1
KRAS WILD-TYPE	159	231	64	165

'KRAS MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S925. Gene #80: 'KRAS MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
KRAS MUTATED	1	1	1
KRAS WILD-TYPE	194	185	188

'KRAS MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S926. Gene #80: 'KRAS MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
KRAS MUTATED	2	0	1
KRAS WILD-TYPE	202	219	146

'KRAS MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S927. Gene #80: 'KRAS MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KRAS MUTATED	1	1	1
KRAS WILD-TYPE	226	234	191

'KRAS MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S928. Gene #80: 'KRAS MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KRAS MUTATED	1	0	2
KRAS WILD-TYPE	195	190	266

'OAS2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S929. Gene #81: 'OAS2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
OAS2 MUTATED	1	0	1	1
OAS2 WILD-TYPE	68	43	73	53

'OAS2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.702 (Fisher's exact test), Q value = 1

Table S930. Gene #81: 'OAS2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
OAS2 MUTATED	0	1	1	1
OAS2 WILD-TYPE	63	49	47	78

'OAS2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S931. Gene #81: 'OAS2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
OAS2 MUTATED	0	2	0	1
OAS2 WILD-TYPE	77	91	45	59

'OAS2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.791 (Fisher's exact test), Q value = 1

Table S932. Gene #81: 'OAS2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
OAS2 MUTATED	1	1	1
OAS2 WILD-TYPE	137	60	75

'OAS2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 0.85

Table S933. Gene #81: 'OAS2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
OAS2 MUTATED	3	1	0
OAS2 WILD-TYPE	292	480	7

'OAS2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.272 (Fisher's exact test), Q value = 0.95

Table S934. Gene #81: 'OAS2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
OAS2 MUTATED	3	1	0
OAS2 WILD-TYPE	224	234	192

'OAS2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.104 (Fisher's exact test), Q value = 0.64

Table S935. Gene #81: 'OAS2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
OAS2 MUTATED	3	1	0
OAS2 WILD-TYPE	193	189	268

'MAP3K1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S936. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
MAP3K1 MUTATED	1	1	2	1
MAP3K1 WILD-TYPE	68	42	72	53

'MAP3K1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.73 (Fisher's exact test), Q value = 1

Table S937. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MAP3K1 MUTATED	1	1	2	1
MAP3K1 WILD-TYPE	62	49	46	78

'MAP3K1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.807 (Fisher's exact test), Q value = 1

Table S938. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
MAP3K1 MUTATED	2	2	0	2
MAP3K1 WILD-TYPE	75	91	45	58

'MAP3K1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S939. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MAP3K1 MUTATED	2	2	2
MAP3K1 WILD-TYPE	136	59	74

'MAP3K1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.162 (Fisher's exact test), Q value = 0.8

Table S940. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MAP3K1 MUTATED	6	3	0
MAP3K1 WILD-TYPE	289	478	7

'MAP3K1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S941. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MAP3K1 MUTATED	2	2	0	0
MAP3K1 WILD-TYPE	158	230	64	166

'MAP3K1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S942. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MAP3K1 MUTATED	1	1	3
MAP3K1 WILD-TYPE	194	185	186

'MAP3K1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.455 (Fisher's exact test), Q value = 1

Table S943. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MAP3K1 MUTATED	2	3	0
MAP3K1 WILD-TYPE	202	216	147

'MAP3K1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.81

Table S944. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MAP3K1 MUTATED	5	1	1
MAP3K1 WILD-TYPE	222	234	191

'MAP3K1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.272 (Fisher's exact test), Q value = 0.95

Table S945. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MAP3K1 MUTATED	4	2	1
MAP3K1 WILD-TYPE	192	188	267

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S946. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MAP3K1 MUTATED	0	2	1	0
MAP3K1 WILD-TYPE	136	105	182	83

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0517 (Fisher's exact test), Q value = 0.43

Table S947. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MAP3K1 MUTATED	0	1	2
MAP3K1 WILD-TYPE	222	183	101

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.86

Table S948. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MAP3K1 MUTATED	0	1	2
MAP3K1 WILD-TYPE	184	161	157

'MAP3K1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S949. Gene #82: 'MAP3K1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MAP3K1 MUTATED	0	1	2	0
MAP3K1 WILD-TYPE	90	137	186	89

'TRPV6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S950. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TRPV6 MUTATED	0	2	2	2
TRPV6 WILD-TYPE	69	41	72	52

'TRPV6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.225 (Fisher's exact test), Q value = 0.89

Table S951. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TRPV6 MUTATED	0	3	1	2
TRPV6 WILD-TYPE	63	47	47	77

'TRPV6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S952. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TRPV6 MUTATED	0	4	2	1
TRPV6 WILD-TYPE	77	89	43	59

'TRPV6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S953. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TRPV6 MUTATED	4	1	2
TRPV6 WILD-TYPE	134	60	74

'TRPV6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.45 (Fisher's exact test), Q value = 1

Table S954. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TRPV6 MUTATED	6	6	0
TRPV6 WILD-TYPE	289	475	7

'TRPV6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S955. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TRPV6 MUTATED	3	2	0	2
TRPV6 WILD-TYPE	157	230	64	164

'TRPV6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S956. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TRPV6 MUTATED	3	4	1
TRPV6 WILD-TYPE	192	182	188

'TRPV6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S957. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TRPV6 MUTATED	1	4	3
TRPV6 WILD-TYPE	203	215	144

'TRPV6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0769 (Fisher's exact test), Q value = 0.53

Table S958. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TRPV6 MUTATED	7	1	3
TRPV6 WILD-TYPE	220	234	189

'TRPV6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.506 (Fisher's exact test), Q value = 1

Table S959. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TRPV6 MUTATED	5	3	3
TRPV6 WILD-TYPE	191	187	265

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S960. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TRPV6 MUTATED	1	2	3	0
TRPV6 WILD-TYPE	135	105	180	83

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S961. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TRPV6 MUTATED	3	1	2
TRPV6 WILD-TYPE	219	183	101

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S962. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TRPV6 MUTATED	2	1	3
TRPV6 WILD-TYPE	182	161	156

'TRPV6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.495 (Fisher's exact test), Q value = 1

Table S963. Gene #83: 'TRPV6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TRPV6 MUTATED	0	1	4	1
TRPV6 WILD-TYPE	90	137	184	88

'MAP3K12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S964. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MAP3K12 MUTATED	1	5	0
MAP3K12 WILD-TYPE	294	476	7

'MAP3K12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S965. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MAP3K12 MUTATED	1	1	0	3
MAP3K12 WILD-TYPE	159	231	64	163

'MAP3K12 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S966. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MAP3K12 MUTATED	3	1	1
MAP3K12 WILD-TYPE	192	185	188

'MAP3K12 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S967. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MAP3K12 MUTATED	2	2	1
MAP3K12 WILD-TYPE	202	217	146

'MAP3K12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S968. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MAP3K12 MUTATED	1	1	3
MAP3K12 WILD-TYPE	226	234	189

'MAP3K12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S969. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MAP3K12 MUTATED	0	2	3
MAP3K12 WILD-TYPE	196	188	265

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S970. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MAP3K12 MUTATED	0	1	3	1
MAP3K12 WILD-TYPE	136	106	180	82

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S971. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MAP3K12 MUTATED	1	3	1
MAP3K12 WILD-TYPE	221	181	102

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.81

Table S972. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MAP3K12 MUTATED	0	2	3
MAP3K12 WILD-TYPE	184	160	156

'MAP3K12 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.666 (Fisher's exact test), Q value = 1

Table S973. Gene #84: 'MAP3K12 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MAP3K12 MUTATED	0	2	3	0
MAP3K12 WILD-TYPE	90	136	185	89

'TLR7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.173 (Fisher's exact test), Q value = 0.82

Table S974. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TLR7 MUTATED	0	2	1	0
TLR7 WILD-TYPE	69	41	73	54

'TLR7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.477 (Fisher's exact test), Q value = 1

Table S975. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TLR7 MUTATED	1	1	1	0
TLR7 WILD-TYPE	62	49	47	79

'TLR7 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S976. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TLR7 MUTATED	1	2	1	0
TLR7 WILD-TYPE	76	91	44	60

'TLR7 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S977. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TLR7 MUTATED	2	0	2
TLR7 WILD-TYPE	136	61	74

'TLR7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S978. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TLR7 MUTATED	5	5	0
TLR7 WILD-TYPE	290	476	7

'TLR7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.128 (Fisher's exact test), Q value = 0.7

Table S979. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TLR7 MUTATED	6	3	0	1
TLR7 WILD-TYPE	154	229	64	165

'TLR7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S980. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TLR7 MUTATED	2	4	3
TLR7 WILD-TYPE	193	182	186

'TLR7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.588 (Fisher's exact test), Q value = 1

Table S981. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TLR7 MUTATED	4	2	3
TLR7 WILD-TYPE	200	217	144

'TLR7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.676 (Fisher's exact test), Q value = 1

Table S982. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TLR7 MUTATED	4	2	2
TLR7 WILD-TYPE	223	233	190

'TLR7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S983. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TLR7 MUTATED	3	3	2
TLR7 WILD-TYPE	193	187	266

'TLR7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S984. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TLR7 MUTATED	2	1	2	1
TLR7 WILD-TYPE	134	106	181	82

'TLR7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.757 (Fisher's exact test), Q value = 1

Table S985. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TLR7 MUTATED	2	2	2
TLR7 WILD-TYPE	220	182	101

'TLR7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.295 (Fisher's exact test), Q value = 0.97

Table S986. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TLR7 MUTATED	1	1	4
TLR7 WILD-TYPE	183	161	155

'TLR7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S987. Gene #85: 'TLR7 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TLR7 MUTATED	1	0	4	1
TLR7 WILD-TYPE	89	138	184	88

'TREML2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0887 (Fisher's exact test), Q value = 0.59

Table S988. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TREML2 MUTATED	0	1	0	2
TREML2 WILD-TYPE	69	42	74	52

'TREML2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S989. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TREML2 MUTATED	1	1	0	1
TREML2 WILD-TYPE	62	49	48	78

'TREML2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.538 (Fisher's exact test), Q value = 1

Table S990. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TREML2 MUTATED	0	2	1	1
TREML2 WILD-TYPE	77	91	44	59

'TREML2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.812 (Fisher's exact test), Q value = 1

Table S991. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TREML2 MUTATED	3	0	1
TREML2 WILD-TYPE	135	61	75

'TREML2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S992. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TREML2 MUTATED	2	4	0
TREML2 WILD-TYPE	293	477	7

'TREML2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.801 (Fisher's exact test), Q value = 1

Table S993. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TREML2 MUTATED	2	1	0	1
TREML2 WILD-TYPE	158	231	64	165

'TREML2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S994. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TREML2 MUTATED	2	2	2
TREML2 WILD-TYPE	193	184	187

'TREML2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S995. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TREML2 MUTATED	2	2	2
TREML2 WILD-TYPE	202	217	145

'TREML2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.336 (Fisher's exact test), Q value = 1

Table S996. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TREML2 MUTATED	4	1	1
TREML2 WILD-TYPE	223	234	191

'TREML2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S997. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TREML2 MUTATED	3	1	2
TREML2 WILD-TYPE	193	189	266

'TREML2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S998. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TREML2 MUTATED	0	1	1	1
TREML2 WILD-TYPE	136	106	182	82

'TREML2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S999. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TREML2 MUTATED	1	1	1
TREML2 WILD-TYPE	221	183	102

'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 0.85

Table S1000. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TREML2 MUTATED	0	1	2
TREML2 WILD-TYPE	184	161	157

'TREML2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1001. Gene #86: 'TREML2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TREML2 MUTATED	0	1	2	0
TREML2 WILD-TYPE	90	137	186	89

'MACC1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.783 (Fisher's exact test), Q value = 1

Table S1002. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
MACC1 MUTATED	1	0	2	0
MACC1 WILD-TYPE	68	43	72	54

'MACC1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 0.67

Table S1003. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MACC1 MUTATED	1	0	2	0
MACC1 WILD-TYPE	62	50	46	79

'MACC1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.182 (Fisher's exact test), Q value = 0.85

Table S1004. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
MACC1 MUTATED	2	0	0	2
MACC1 WILD-TYPE	75	93	45	58

'MACC1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.259 (Fisher's exact test), Q value = 0.95

Table S1005. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MACC1 MUTATED	2	2	0
MACC1 WILD-TYPE	136	59	76

'MACC1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.223 (Fisher's exact test), Q value = 0.88

Table S1006. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MACC1 MUTATED	5	3	0
MACC1 WILD-TYPE	290	478	7

'MACC1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.143 (Fisher's exact test), Q value = 0.75

Table S1007. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MACC1 MUTATED	4	2	0	0
MACC1 WILD-TYPE	156	230	64	166

'MACC1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0893 (Fisher's exact test), Q value = 0.59

Table S1008. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MACC1 MUTATED	1	0	4
MACC1 WILD-TYPE	194	186	185

'MACC1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 0.85

Table S1009. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MACC1 MUTATED	4	1	0
MACC1 WILD-TYPE	200	218	147

'MACC1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.88

Table S1010. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MACC1 MUTATED	4	2	0
MACC1 WILD-TYPE	223	233	192

'MACC1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0567 (Fisher's exact test), Q value = 0.45

Table S1011. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MACC1 MUTATED	3	3	0
MACC1 WILD-TYPE	193	187	268

'MACC1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.192 (Fisher's exact test), Q value = 0.85

Table S1012. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MACC1 MUTATED	1	2	0	1
MACC1 WILD-TYPE	135	105	183	82

'MACC1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.85

Table S1013. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MACC1 MUTATED	2	0	2
MACC1 WILD-TYPE	220	184	101

'MACC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.841 (Fisher's exact test), Q value = 1

Table S1014. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MACC1 MUTATED	1	2	1
MACC1 WILD-TYPE	183	160	158

'MACC1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.638 (Fisher's exact test), Q value = 1

Table S1015. Gene #87: 'MACC1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MACC1 MUTATED	0	2	1	1
MACC1 WILD-TYPE	90	136	187	88

'AOX1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S1016. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
AOX1 MUTATED	0	1	1	2
AOX1 WILD-TYPE	69	42	73	52

'AOX1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.95

Table S1017. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
AOX1 MUTATED	0	2	0	2
AOX1 WILD-TYPE	63	48	48	77

'AOX1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.67

Table S1018. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
AOX1 MUTATED	0	2	2	0
AOX1 WILD-TYPE	77	91	43	60

'AOX1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.85

Table S1019. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
AOX1 MUTATED	4	0	0
AOX1 WILD-TYPE	134	61	76

'AOX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.88

Table S1020. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
AOX1 MUTATED	5	3	0
AOX1 WILD-TYPE	290	478	7

'AOX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.545 (Fisher's exact test), Q value = 1

Table S1021. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
AOX1 MUTATED	2	2	0	0
AOX1 WILD-TYPE	158	230	64	166

'AOX1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S1022. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
AOX1 MUTATED	1	2	3
AOX1 WILD-TYPE	194	184	186

'AOX1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S1023. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
AOX1 MUTATED	2	3	1
AOX1 WILD-TYPE	202	216	146

'AOX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0923 (Fisher's exact test), Q value = 0.59

Table S1024. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
AOX1 MUTATED	6	1	1
AOX1 WILD-TYPE	221	234	191

'AOX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.107 (Fisher's exact test), Q value = 0.65

Table S1025. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
AOX1 MUTATED	5	2	1
AOX1 WILD-TYPE	191	188	267

'AOX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0442 (Fisher's exact test), Q value = 0.41

Table S1026. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AOX1 MUTATED	1	3	0	0
AOX1 WILD-TYPE	135	104	183	83

Figure S210. Get High-res Image Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'AOX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0281 (Fisher's exact test), Q value = 0.3

Table S1027. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AOX1 MUTATED	1	0	3
AOX1 WILD-TYPE	221	184	100

Figure S211. Get High-res Image Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'AOX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.27 (Fisher's exact test), Q value = 0.95

Table S1028. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AOX1 MUTATED	3	0	1
AOX1 WILD-TYPE	181	162	158

'AOX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S1029. Gene #88: 'AOX1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AOX1 MUTATED	0	1	2	1
AOX1 WILD-TYPE	90	137	186	88

'HEATR3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S1030. Gene #89: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
HEATR3 MUTATED	2	2	0
HEATR3 WILD-TYPE	293	479	7

'HEATR3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.97

Table S1031. Gene #89: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
HEATR3 MUTATED	2	0	0	1
HEATR3 WILD-TYPE	158	232	64	165

'HEATR3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1032. Gene #89: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
HEATR3 MUTATED	2	0	1
HEATR3 WILD-TYPE	193	186	188

'HEATR3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S1033. Gene #89: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
HEATR3 MUTATED	2	1	0
HEATR3 WILD-TYPE	202	218	147

'HEATR3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.645 (Fisher's exact test), Q value = 1

Table S1034. Gene #89: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
HEATR3 MUTATED	2	1	0
HEATR3 WILD-TYPE	225	234	192

'HEATR3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1035. Gene #89: 'HEATR3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
HEATR3 MUTATED	1	1	1
HEATR3 WILD-TYPE	195	189	267

'KRT13 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S1036. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
KRT13 MUTATED	1	0	2	0
KRT13 WILD-TYPE	68	43	72	54

'KRT13 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.67

Table S1037. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
KRT13 MUTATED	1	0	2	0
KRT13 WILD-TYPE	62	50	46	79

'KRT13 MUTATION STATUS' versus 'MIR_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1038. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
KRT13 MUTATED	1	1	0	1
KRT13 WILD-TYPE	76	92	45	59

'KRT13 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.072 (Fisher's exact test), Q value = 0.51

Table S1039. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
KRT13 MUTATED	0	2	1
KRT13 WILD-TYPE	138	59	75

'KRT13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.251 (Fisher's exact test), Q value = 0.94

Table S1040. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KRT13 MUTATED	4	2	0
KRT13 WILD-TYPE	291	479	7

'KRT13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S1041. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KRT13 MUTATED	2	2	0	0
KRT13 WILD-TYPE	158	230	64	166

'KRT13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.79

Table S1042. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KRT13 MUTATED	3	0	1
KRT13 WILD-TYPE	224	235	191

'KRT13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1043. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KRT13 MUTATED	2	1	1
KRT13 WILD-TYPE	194	189	267

'KRT13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.33 (Fisher's exact test), Q value = 1

Table S1044. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KRT13 MUTATED	0	2	1	0
KRT13 WILD-TYPE	136	105	182	83

'KRT13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0523 (Fisher's exact test), Q value = 0.43

Table S1045. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KRT13 MUTATED	0	1	2
KRT13 WILD-TYPE	222	183	101

'KRT13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1046. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KRT13 MUTATED	1	1	1
KRT13 WILD-TYPE	183	161	158

'KRT13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.78

Table S1047. Gene #90: 'KRT13 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KRT13 MUTATED	0	0	1	2
KRT13 WILD-TYPE	90	138	187	87

'CNOT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.319 (Fisher's exact test), Q value = 0.99

Table S1048. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CNOT1 MUTATED	1	7	0
CNOT1 WILD-TYPE	294	474	7

'CNOT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1049. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CNOT1 MUTATED	1	4	0	2
CNOT1 WILD-TYPE	159	228	64	164

'CNOT1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1050. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CNOT1 MUTATED	3	2	2
CNOT1 WILD-TYPE	192	184	187

'CNOT1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1051. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CNOT1 MUTATED	2	3	2
CNOT1 WILD-TYPE	202	216	145

'CNOT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.825 (Fisher's exact test), Q value = 1

Table S1052. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CNOT1 MUTATED	3	2	3
CNOT1 WILD-TYPE	224	233	189

'CNOT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0484 (Fisher's exact test), Q value = 0.42

Table S1053. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CNOT1 MUTATED	0	5	3
CNOT1 WILD-TYPE	196	185	265

Figure S212. Get High-res Image Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.766 (Fisher's exact test), Q value = 1

Table S1054. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CNOT1 MUTATED	2	2	3	0
CNOT1 WILD-TYPE	134	105	180	83

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.691 (Fisher's exact test), Q value = 1

Table S1055. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CNOT1 MUTATED	2	3	2
CNOT1 WILD-TYPE	220	181	101

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S1056. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CNOT1 MUTATED	2	2	3
CNOT1 WILD-TYPE	182	160	156

'CNOT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S1057. Gene #91: 'CNOT1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CNOT1 MUTATED	1	3	3	0
CNOT1 WILD-TYPE	89	135	185	89

'ESR2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S1058. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
ESR2 MUTATED	0	0	2	1
ESR2 WILD-TYPE	69	43	72	53

'ESR2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S1059. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
ESR2 MUTATED	0	1	1	1
ESR2 WILD-TYPE	63	49	47	78

'ESR2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.781 (Fisher's exact test), Q value = 1

Table S1060. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
ESR2 MUTATED	1	1	1	0
ESR2 WILD-TYPE	76	92	44	60

'ESR2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.435 (Fisher's exact test), Q value = 1

Table S1061. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
ESR2 MUTATED	3	0	0
ESR2 WILD-TYPE	135	61	76

'ESR2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1062. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ESR2 MUTATED	2	3	0
ESR2 WILD-TYPE	293	478	7

'ESR2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.806 (Fisher's exact test), Q value = 1

Table S1063. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ESR2 MUTATED	2	1	0	1
ESR2 WILD-TYPE	158	231	64	165

'ESR2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1064. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ESR2 MUTATED	2	1	2
ESR2 WILD-TYPE	193	185	187

'ESR2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.747 (Fisher's exact test), Q value = 1

Table S1065. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ESR2 MUTATED	1	3	1
ESR2 WILD-TYPE	203	216	146

'ESR2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S1066. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ESR2 MUTATED	2	2	0
ESR2 WILD-TYPE	225	233	192

'ESR2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S1067. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ESR2 MUTATED	1	2	1
ESR2 WILD-TYPE	195	188	267

'ESR2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.85

Table S1068. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ESR2 MUTATED	1	2	0	0
ESR2 WILD-TYPE	135	105	183	83

'ESR2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.43 (Fisher's exact test), Q value = 1

Table S1069. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ESR2 MUTATED	2	0	1
ESR2 WILD-TYPE	220	184	102

'ESR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1070. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ESR2 MUTATED	1	1	1
ESR2 WILD-TYPE	183	161	158

'ESR2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1071. Gene #92: 'ESR2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ESR2 MUTATED	0	1	2	0
ESR2 WILD-TYPE	90	137	186	89

'GRHL3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S1072. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
GRHL3 MUTATED	1	0	2	1
GRHL3 WILD-TYPE	68	43	72	53

'GRHL3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1073. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
GRHL3 MUTATED	1	1	1	1
GRHL3 WILD-TYPE	62	49	47	78

'GRHL3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1074. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
GRHL3 MUTATED	1	2	0	1
GRHL3 WILD-TYPE	76	91	45	59

'GRHL3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.446 (Fisher's exact test), Q value = 1

Table S1075. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
GRHL3 MUTATED	1	1	2
GRHL3 WILD-TYPE	137	60	74

'GRHL3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.166 (Fisher's exact test), Q value = 0.81

Table S1076. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
GRHL3 MUTATED	5	2	0
GRHL3 WILD-TYPE	290	479	7

'GRHL3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0798 (Fisher's exact test), Q value = 0.55

Table S1077. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
GRHL3 MUTATED	4	1	1	0
GRHL3 WILD-TYPE	156	231	63	166

'GRHL3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.75 (Fisher's exact test), Q value = 1

Table S1078. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
GRHL3 MUTATED	1	2	2
GRHL3 WILD-TYPE	194	184	187

'GRHL3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.639 (Fisher's exact test), Q value = 1

Table S1079. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
GRHL3 MUTATED	2	1	2
GRHL3 WILD-TYPE	202	218	145

'GRHL3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0225 (Fisher's exact test), Q value = 0.26

Table S1080. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
GRHL3 MUTATED	5	0	1
GRHL3 WILD-TYPE	222	235	191

Figure S213. Get High-res Image Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'GRHL3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S1081. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
GRHL3 MUTATED	3	2	1
GRHL3 WILD-TYPE	193	188	267

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.589 (Fisher's exact test), Q value = 1

Table S1082. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GRHL3 MUTATED	1	2	1	0
GRHL3 WILD-TYPE	135	105	182	83

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0133 (Fisher's exact test), Q value = 0.19

Table S1083. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GRHL3 MUTATED	0	1	3
GRHL3 WILD-TYPE	222	183	100

Figure S214. Get High-res Image Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.163 (Fisher's exact test), Q value = 0.8

Table S1084. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GRHL3 MUTATED	1	0	3
GRHL3 WILD-TYPE	183	162	156

'GRHL3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.236 (Fisher's exact test), Q value = 0.91

Table S1085. Gene #93: 'GRHL3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GRHL3 MUTATED	0	0	2	2
GRHL3 WILD-TYPE	90	138	186	87

'RASGRF2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S1086. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
RASGRF2 MUTATED	3	3	0
RASGRF2 WILD-TYPE	292	478	7

'RASGRF2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 0.86

Table S1087. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
RASGRF2 MUTATED	4	1	0	1
RASGRF2 WILD-TYPE	156	231	64	165

'RASGRF2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1088. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
RASGRF2 MUTATED	2	1	1
RASGRF2 WILD-TYPE	193	185	188

'RASGRF2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1089. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
RASGRF2 MUTATED	1	2	1
RASGRF2 WILD-TYPE	203	217	146

'RASGRF2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.335 (Fisher's exact test), Q value = 1

Table S1090. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
RASGRF2 MUTATED	4	1	1
RASGRF2 WILD-TYPE	223	234	191

'RASGRF2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.67 (Fisher's exact test), Q value = 1

Table S1091. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
RASGRF2 MUTATED	3	1	2
RASGRF2 WILD-TYPE	193	189	266

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0808 (Fisher's exact test), Q value = 0.56

Table S1092. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RASGRF2 MUTATED	0	3	1	0
RASGRF2 WILD-TYPE	136	104	182	83

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0133 (Fisher's exact test), Q value = 0.19

Table S1093. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RASGRF2 MUTATED	0	1	3
RASGRF2 WILD-TYPE	222	183	100

Figure S215. Get High-res Image Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S1094. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RASGRF2 MUTATED	1	2	1
RASGRF2 WILD-TYPE	183	160	158

'RASGRF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.635 (Fisher's exact test), Q value = 1

Table S1095. Gene #94: 'RASGRF2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RASGRF2 MUTATED	0	2	1	1
RASGRF2 WILD-TYPE	90	136	187	88

'PAK1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1096. Gene #95: 'PAK1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PAK1 MUTATED	1	2	0
PAK1 WILD-TYPE	294	479	7

'PAK1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S1097. Gene #95: 'PAK1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PAK1 MUTATED	2	1	0	0
PAK1 WILD-TYPE	158	231	64	166

'PAK1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1098. Gene #95: 'PAK1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PAK1 MUTATED	2	0	1
PAK1 WILD-TYPE	193	186	188

'PAK1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.631 (Fisher's exact test), Q value = 1

Table S1099. Gene #95: 'PAK1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PAK1 MUTATED	2	1	0
PAK1 WILD-TYPE	202	218	147

'SLC35A2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1100. Gene #96: 'SLC35A2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SLC35A2 MUTATED	1	2	0
SLC35A2 WILD-TYPE	294	479	7

'SLC35A2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1101. Gene #96: 'SLC35A2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SLC35A2 MUTATED	1	1	1
SLC35A2 WILD-TYPE	226	234	191

'SLC35A2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1102. Gene #96: 'SLC35A2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SLC35A2 MUTATED	1	1	1
SLC35A2 WILD-TYPE	195	189	267

'LGALS13 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1103. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
LGALS13 MUTATED	1	3	0
LGALS13 WILD-TYPE	294	478	7

'LGALS13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0176 (Fisher's exact test), Q value = 0.23

Table S1104. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
LGALS13 MUTATED	0	0	2	1
LGALS13 WILD-TYPE	160	232	62	165

Figure S216. Get High-res Image Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'LGALS13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1105. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
LGALS13 MUTATED	1	1	1
LGALS13 WILD-TYPE	226	234	191

'LGALS13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S1106. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
LGALS13 MUTATED	1	0	2
LGALS13 WILD-TYPE	195	190	266

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0486 (Fisher's exact test), Q value = 0.42

Table S1107. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
LGALS13 MUTATED	3	0	0	0
LGALS13 WILD-TYPE	133	107	183	83

Figure S217. Get High-res Image Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.313 (Fisher's exact test), Q value = 0.98

Table S1108. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
LGALS13 MUTATED	3	0	0
LGALS13 WILD-TYPE	219	184	103

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.65

Table S1109. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
LGALS13 MUTATED	3	0	0
LGALS13 WILD-TYPE	181	162	159

'LGALS13 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.224 (Fisher's exact test), Q value = 0.88

Table S1110. Gene #97: 'LGALS13 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
LGALS13 MUTATED	0	2	0	1
LGALS13 WILD-TYPE	90	136	188	88

'CDKN2A MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1111. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CDKN2A MUTATED	2	4	0
CDKN2A WILD-TYPE	293	477	7

'CDKN2A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1112. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CDKN2A MUTATED	1	2	0	1
CDKN2A WILD-TYPE	159	230	64	165

'CDKN2A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.552 (Fisher's exact test), Q value = 1

Table S1113. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CDKN2A MUTATED	2	0	2
CDKN2A WILD-TYPE	193	186	187

'CDKN2A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S1114. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CDKN2A MUTATED	2	2	0
CDKN2A WILD-TYPE	202	217	147

'CDKN2A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 0.97

Table S1115. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CDKN2A MUTATED	3	3	0
CDKN2A WILD-TYPE	224	232	192

'CDKN2A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.386 (Fisher's exact test), Q value = 1

Table S1116. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CDKN2A MUTATED	2	3	1
CDKN2A WILD-TYPE	194	187	267

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0217 (Fisher's exact test), Q value = 0.26

Table S1117. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CDKN2A MUTATED	0	3	0	1
CDKN2A WILD-TYPE	136	104	183	82

Figure S218. Get High-res Image Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.262 (Fisher's exact test), Q value = 0.95

Table S1118. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CDKN2A MUTATED	3	0	1
CDKN2A WILD-TYPE	219	184	102

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.118 (Fisher's exact test), Q value = 0.67

Table S1119. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CDKN2A MUTATED	0	3	1
CDKN2A WILD-TYPE	184	159	158

'CDKN2A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.76 (Fisher's exact test), Q value = 1

Table S1120. Gene #98: 'CDKN2A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CDKN2A MUTATED	0	2	2	0
CDKN2A WILD-TYPE	90	136	186	89

'DOCK5 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.26 (Fisher's exact test), Q value = 0.95

Table S1121. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
DOCK5 MUTATED	4	3	1	1
DOCK5 WILD-TYPE	65	40	73	53

'DOCK5 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.908 (Fisher's exact test), Q value = 1

Table S1122. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
DOCK5 MUTATED	2	2	1	4
DOCK5 WILD-TYPE	61	48	47	75

'DOCK5 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0593 (Fisher's exact test), Q value = 0.46

Table S1123. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
DOCK5 MUTATED	6	1	0	3
DOCK5 WILD-TYPE	71	92	45	57

'DOCK5 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.299 (Fisher's exact test), Q value = 0.97

Table S1124. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
DOCK5 MUTATED	3	4	3
DOCK5 WILD-TYPE	135	57	73

'DOCK5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0253 (Fisher's exact test), Q value = 0.28

Table S1125. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
DOCK5 MUTATED	13	6	0
DOCK5 WILD-TYPE	282	475	7

Figure S219. Get High-res Image Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'DOCK5 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0346 (Fisher's exact test), Q value = 0.35

Table S1126. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
DOCK5 MUTATED	8	4	0	1
DOCK5 WILD-TYPE	152	228	64	165

Figure S220. Get High-res Image Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'DOCK5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0267 (Fisher's exact test), Q value = 0.29

Table S1127. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
DOCK5 MUTATED	4	1	9
DOCK5 WILD-TYPE	191	185	180

Figure S221. Get High-res Image Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'DOCK5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.165 (Fisher's exact test), Q value = 0.81

Table S1128. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
DOCK5 MUTATED	8	5	1
DOCK5 WILD-TYPE	196	214	146

'DOCK5 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0121 (Fisher's exact test), Q value = 0.18

Table S1129. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
DOCK5 MUTATED	12	3	2
DOCK5 WILD-TYPE	215	232	190

Figure S222. Get High-res Image Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'DOCK5 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00543 (Fisher's exact test), Q value = 0.1

Table S1130. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
DOCK5 MUTATED	11	4	2
DOCK5 WILD-TYPE	185	186	266

Figure S223. Get High-res Image Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0384 (Fisher's exact test), Q value = 0.37

Table S1131. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
DOCK5 MUTATED	2	6	2	0
DOCK5 WILD-TYPE	134	101	181	83

Figure S224. Get High-res Image Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0663 (Fisher's exact test), Q value = 0.49

Table S1132. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
DOCK5 MUTATED	2	3	5
DOCK5 WILD-TYPE	220	181	98

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.727 (Fisher's exact test), Q value = 1

Table S1133. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
DOCK5 MUTATED	4	2	4
DOCK5 WILD-TYPE	180	160	155

'DOCK5 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.46 (Fisher's exact test), Q value = 1

Table S1134. Gene #99: 'DOCK5 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
DOCK5 MUTATED	1	1	5	3
DOCK5 WILD-TYPE	89	137	183	86

'TYRP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1135. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TYRP1 MUTATED	2	4	0
TYRP1 WILD-TYPE	293	477	7

'TYRP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S1136. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TYRP1 MUTATED	2	2	0	1
TYRP1 WILD-TYPE	158	230	64	165

'TYRP1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1137. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TYRP1 MUTATED	1	1	1
TYRP1 WILD-TYPE	194	185	188

'TYRP1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S1138. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TYRP1 MUTATED	2	0	1
TYRP1 WILD-TYPE	202	219	146

'TYRP1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1139. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TYRP1 MUTATED	3	2	1
TYRP1 WILD-TYPE	224	233	191

'TYRP1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S1140. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TYRP1 MUTATED	2	3	1
TYRP1 WILD-TYPE	194	187	267

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S1141. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TYRP1 MUTATED	0	2	2	0
TYRP1 WILD-TYPE	136	105	181	83

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.342 (Fisher's exact test), Q value = 1

Table S1142. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TYRP1 MUTATED	1	1	2
TYRP1 WILD-TYPE	221	183	101

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S1143. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TYRP1 MUTATED	1	1	2
TYRP1 WILD-TYPE	183	161	157

'TYRP1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.36 (Fisher's exact test), Q value = 1

Table S1144. Gene #100: 'TYRP1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TYRP1 MUTATED	0	0	3	1
TYRP1 WILD-TYPE	90	138	185	88

'CD99L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.669 (Fisher's exact test), Q value = 1

Table S1145. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CD99L2 MUTATED	1	4	0
CD99L2 WILD-TYPE	294	477	7

'CD99L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.85

Table S1146. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CD99L2 MUTATED	1	0	1	2
CD99L2 WILD-TYPE	159	232	63	164

'CD99L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1147. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CD99L2 MUTATED	2	1	1
CD99L2 WILD-TYPE	193	185	188

'CD99L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.834 (Fisher's exact test), Q value = 1

Table S1148. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CD99L2 MUTATED	2	1	1
CD99L2 WILD-TYPE	202	218	146

'CD99L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1149. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CD99L2 MUTATED	2	2	1
CD99L2 WILD-TYPE	225	233	191

'CD99L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S1150. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CD99L2 MUTATED	1	1	3
CD99L2 WILD-TYPE	195	189	265

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 0.88

Table S1151. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CD99L2 MUTATED	0	1	1	2
CD99L2 WILD-TYPE	136	106	182	81

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1152. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CD99L2 MUTATED	2	1	1
CD99L2 WILD-TYPE	220	183	102

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S1153. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CD99L2 MUTATED	1	1	2
CD99L2 WILD-TYPE	183	161	157

'CD99L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.58 (Fisher's exact test), Q value = 1

Table S1154. Gene #101: 'CD99L2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CD99L2 MUTATED	0	1	3	0
CD99L2 WILD-TYPE	90	137	185	89

'MORN5 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.575 (Fisher's exact test), Q value = 1

Table S1155. Gene #102: 'MORN5 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MORN5 MUTATED	2	1	0
MORN5 WILD-TYPE	293	480	7

'MORN5 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.218 (Fisher's exact test), Q value = 0.88

Table S1156. Gene #102: 'MORN5 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MORN5 MUTATED	0	2	1
MORN5 WILD-TYPE	195	184	188

'MORN5 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S1157. Gene #102: 'MORN5 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MORN5 MUTATED	0	2	1
MORN5 WILD-TYPE	204	217	146

'SMARCA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00202 (Fisher's exact test), Q value = 0.047

Table S1158. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SMARCA4 MUTATED	2	25	0
SMARCA4 WILD-TYPE	293	456	7

Figure S225. Get High-res Image Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'SMARCA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0163 (Fisher's exact test), Q value = 0.22

Table S1159. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SMARCA4 MUTATED	3	17	0	7
SMARCA4 WILD-TYPE	157	215	64	159

Figure S226. Get High-res Image Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SMARCA4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.95

Table S1160. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SMARCA4 MUTATED	10	5	4
SMARCA4 WILD-TYPE	185	181	185

'SMARCA4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S1161. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SMARCA4 MUTATED	8	6	5
SMARCA4 WILD-TYPE	196	213	142

'SMARCA4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00576 (Fisher's exact test), Q value = 0.11

Table S1162. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SMARCA4 MUTATED	3	17	7
SMARCA4 WILD-TYPE	224	218	185

Figure S227. Get High-res Image Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'SMARCA4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00973 (Fisher's exact test), Q value = 0.15

Table S1163. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SMARCA4 MUTATED	2	13	12
SMARCA4 WILD-TYPE	194	177	256

Figure S228. Get High-res Image Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.304 (Fisher's exact test), Q value = 0.98

Table S1164. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SMARCA4 MUTATED	8	2	9	6
SMARCA4 WILD-TYPE	128	105	174	77

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.245 (Fisher's exact test), Q value = 0.93

Table S1165. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SMARCA4 MUTATED	14	9	2
SMARCA4 WILD-TYPE	208	175	101

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.873 (Fisher's exact test), Q value = 1

Table S1166. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SMARCA4 MUTATED	8	9	8
SMARCA4 WILD-TYPE	176	153	151

'SMARCA4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.166 (Fisher's exact test), Q value = 0.81

Table S1167. Gene #103: 'SMARCA4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SMARCA4 MUTATED	7	6	11	1
SMARCA4 WILD-TYPE	83	132	177	88

'NAP1L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1168. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NAP1L2 MUTATED	2	4	0
NAP1L2 WILD-TYPE	293	477	7

'NAP1L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.659 (Fisher's exact test), Q value = 1

Table S1169. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NAP1L2 MUTATED	0	2	0	2
NAP1L2 WILD-TYPE	160	230	64	164

'NAP1L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S1170. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NAP1L2 MUTATED	1	2	1
NAP1L2 WILD-TYPE	194	184	188

'NAP1L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.249 (Fisher's exact test), Q value = 0.93

Table S1171. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NAP1L2 MUTATED	0	3	1
NAP1L2 WILD-TYPE	204	216	146

'NAP1L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.861 (Fisher's exact test), Q value = 1

Table S1172. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NAP1L2 MUTATED	1	2	2
NAP1L2 WILD-TYPE	226	233	190

'NAP1L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S1173. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NAP1L2 MUTATED	1	2	2
NAP1L2 WILD-TYPE	195	188	266

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1174. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NAP1L2 MUTATED	1	1	2	0
NAP1L2 WILD-TYPE	135	106	181	83

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.832 (Fisher's exact test), Q value = 1

Table S1175. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NAP1L2 MUTATED	2	2	0
NAP1L2 WILD-TYPE	220	182	103

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1176. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NAP1L2 MUTATED	2	1	1
NAP1L2 WILD-TYPE	182	161	158

'NAP1L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1177. Gene #104: 'NAP1L2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NAP1L2 MUTATED	1	1	2	0
NAP1L2 WILD-TYPE	89	137	186	89

'CD44 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S1178. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
CD44 MUTATED	2	0	1	0
CD44 WILD-TYPE	67	43	73	54

'CD44 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.264 (Fisher's exact test), Q value = 0.95

Table S1179. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CD44 MUTATED	2	0	1	0
CD44 WILD-TYPE	61	50	47	79

'CD44 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.287 (Fisher's exact test), Q value = 0.97

Table S1180. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
CD44 MUTATED	0	1	0	2
CD44 WILD-TYPE	77	92	45	58

'CD44 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.792 (Fisher's exact test), Q value = 1

Table S1181. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CD44 MUTATED	1	1	1
CD44 WILD-TYPE	137	60	75

'CD44 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S1182. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CD44 MUTATED	3	3	0
CD44 WILD-TYPE	292	478	7

'CD44 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1183. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CD44 MUTATED	1	1	0	1
CD44 WILD-TYPE	159	231	64	165

'CD44 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0368 (Fisher's exact test), Q value = 0.36

Table S1184. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CD44 MUTATED	4	0	0
CD44 WILD-TYPE	191	186	189

Figure S229. Get High-res Image Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'CD44 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1185. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CD44 MUTATED	2	2	0
CD44 WILD-TYPE	202	217	147

'CD44 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.204 (Fisher's exact test), Q value = 0.85

Table S1186. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CD44 MUTATED	1	0	2
CD44 WILD-TYPE	226	235	190

'CD44 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S1187. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CD44 MUTATED	0	1	2
CD44 WILD-TYPE	196	189	266

'CD44 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1188. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CD44 MUTATED	0	1	2	0
CD44 WILD-TYPE	136	106	181	83

'CD44 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.233 (Fisher's exact test), Q value = 0.9

Table S1189. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CD44 MUTATED	0	2	1
CD44 WILD-TYPE	222	182	102

'CD44 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.86

Table S1190. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CD44 MUTATED	0	1	2
CD44 WILD-TYPE	184	161	157

'CD44 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1191. Gene #105: 'CD44 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CD44 MUTATED	0	1	2	0
CD44 WILD-TYPE	90	137	186	89

'OR52M1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.505 (Fisher's exact test), Q value = 1

Table S1192. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
OR52M1 MUTATED	2	1	0	1
OR52M1 WILD-TYPE	67	42	74	53

'OR52M1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.605 (Fisher's exact test), Q value = 1

Table S1193. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
OR52M1 MUTATED	1	2	0	1
OR52M1 WILD-TYPE	62	48	48	78

'OR52M1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0886 (Fisher's exact test), Q value = 0.59

Table S1194. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
OR52M1 MUTATED	0	1	0	3
OR52M1 WILD-TYPE	77	92	45	57

'OR52M1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0605 (Fisher's exact test), Q value = 0.46

Table S1195. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
OR52M1 MUTATED	1	3	0
OR52M1 WILD-TYPE	137	58	76

'OR52M1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.222 (Fisher's exact test), Q value = 0.88

Table S1196. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
OR52M1 MUTATED	5	3	0
OR52M1 WILD-TYPE	290	478	7

'OR52M1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S1197. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
OR52M1 MUTATED	2	2	1	0
OR52M1 WILD-TYPE	158	230	63	166

'OR52M1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.703 (Fisher's exact test), Q value = 1

Table S1198. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
OR52M1 MUTATED	2	1	3
OR52M1 WILD-TYPE	193	185	186

'OR52M1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S1199. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
OR52M1 MUTATED	3	2	1
OR52M1 WILD-TYPE	201	217	146

'OR52M1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.574 (Fisher's exact test), Q value = 1

Table S1200. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
OR52M1 MUTATED	4	2	1
OR52M1 WILD-TYPE	223	233	191

'OR52M1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.95

Table S1201. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
OR52M1 MUTATED	4	2	1
OR52M1 WILD-TYPE	192	188	267

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.765 (Fisher's exact test), Q value = 1

Table S1202. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
OR52M1 MUTATED	2	1	1	0
OR52M1 WILD-TYPE	134	106	182	83

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1203. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
OR52M1 MUTATED	2	1	1
OR52M1 WILD-TYPE	220	183	102

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1204. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
OR52M1 MUTATED	2	1	1
OR52M1 WILD-TYPE	182	161	158

'OR52M1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S1205. Gene #106: 'OR52M1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
OR52M1 MUTATED	1	1	1	1
OR52M1 WILD-TYPE	89	137	187	88

'ROBO3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.85

Table S1206. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ROBO3 MUTATED	0	5	0
ROBO3 WILD-TYPE	295	476	7

'ROBO3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.581 (Fisher's exact test), Q value = 1

Table S1207. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ROBO3 MUTATED	0	3	0	2
ROBO3 WILD-TYPE	160	229	64	164

'ROBO3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.278 (Fisher's exact test), Q value = 0.95

Table S1208. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ROBO3 MUTATED	3	1	0
ROBO3 WILD-TYPE	192	185	189

'ROBO3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S1209. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ROBO3 MUTATED	1	3	0
ROBO3 WILD-TYPE	203	216	147

'ROBO3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.275 (Fisher's exact test), Q value = 0.95

Table S1210. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ROBO3 MUTATED	0	3	2
ROBO3 WILD-TYPE	227	232	190

'ROBO3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S1211. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ROBO3 MUTATED	0	2	3
ROBO3 WILD-TYPE	196	188	265

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S1212. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ROBO3 MUTATED	1	0	2	2
ROBO3 WILD-TYPE	135	107	181	81

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.287 (Fisher's exact test), Q value = 0.97

Table S1213. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ROBO3 MUTATED	4	1	0
ROBO3 WILD-TYPE	218	183	103

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1214. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ROBO3 MUTATED	2	2	1
ROBO3 WILD-TYPE	182	160	158

'ROBO3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.927 (Fisher's exact test), Q value = 1

Table S1215. Gene #107: 'ROBO3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ROBO3 MUTATED	1	2	2	0
ROBO3 WILD-TYPE	89	136	186	89

'MYO5A MUTATION STATUS' versus 'CN_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S1216. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MYO5A MUTATED	3	2	0
MYO5A WILD-TYPE	292	479	7

'MYO5A MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0358 (Fisher's exact test), Q value = 0.35

Table S1217. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MYO5A MUTATED	4	0	0	1
MYO5A WILD-TYPE	156	232	64	165

Figure S230. Get High-res Image Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'MYO5A MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.382 (Fisher's exact test), Q value = 1

Table S1218. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MYO5A MUTATED	3	0	2
MYO5A WILD-TYPE	192	186	187

'MYO5A MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.187 (Fisher's exact test), Q value = 0.85

Table S1219. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MYO5A MUTATED	4	1	0
MYO5A WILD-TYPE	200	218	147

'MYO5A MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.158 (Fisher's exact test), Q value = 0.79

Table S1220. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MYO5A MUTATED	3	0	1
MYO5A WILD-TYPE	224	235	191

'MYO5A MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1221. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MYO5A MUTATED	2	1	1
MYO5A WILD-TYPE	194	189	267

'MYO5A MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S1222. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MYO5A MUTATED	2	1	1	0
MYO5A WILD-TYPE	134	106	182	83

'MYO5A MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S1223. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MYO5A MUTATED	1	1	2
MYO5A WILD-TYPE	221	183	101

'MYO5A MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S1224. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MYO5A MUTATED	2	0	2
MYO5A WILD-TYPE	182	162	157

'MYO5A MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.524 (Fisher's exact test), Q value = 1

Table S1225. Gene #108: 'MYO5A MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MYO5A MUTATED	1	0	2	1
MYO5A WILD-TYPE	89	138	186	88

'KRT3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1226. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KRT3 MUTATED	1	3	0
KRT3 WILD-TYPE	294	478	7

'KRT3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1227. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KRT3 MUTATED	1	2	0	1
KRT3 WILD-TYPE	159	230	64	165

'KRT3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1228. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
KRT3 MUTATED	2	0	1
KRT3 WILD-TYPE	193	186	188

'KRT3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.627 (Fisher's exact test), Q value = 1

Table S1229. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
KRT3 MUTATED	2	1	0
KRT3 WILD-TYPE	202	218	147

'KRT3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.398 (Fisher's exact test), Q value = 1

Table S1230. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KRT3 MUTATED	1	3	0
KRT3 WILD-TYPE	226	232	192

'KRT3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S1231. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KRT3 MUTATED	1	2	1
KRT3 WILD-TYPE	195	188	267

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.95

Table S1232. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KRT3 MUTATED	2	1	0	1
KRT3 WILD-TYPE	134	106	183	82

'KRT3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.85

Table S1233. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KRT3 MUTATED	2	0	2
KRT3 WILD-TYPE	220	184	101

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S1234. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KRT3 MUTATED	3	1	0
KRT3 WILD-TYPE	181	161	159

'KRT3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.213 (Fisher's exact test), Q value = 0.87

Table S1235. Gene #109: 'KRT3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KRT3 MUTATED	2	0	1	1
KRT3 WILD-TYPE	88	138	187	88

'GEFT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.185 (Fisher's exact test), Q value = 0.85

Table S1236. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
GEFT MUTATED	3	1	0
GEFT WILD-TYPE	292	480	7

'GEFT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0459 (Fisher's exact test), Q value = 0.41

Table S1237. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
GEFT MUTATED	3	0	0	0
GEFT WILD-TYPE	157	232	64	166

Figure S231. Get High-res Image Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'GEFT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0226 (Fisher's exact test), Q value = 0.26

Table S1238. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
GEFT MUTATED	4	0	0
GEFT WILD-TYPE	223	235	192

Figure S232. Get High-res Image Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'GEFT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.102 (Fisher's exact test), Q value = 0.63

Table S1239. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
GEFT MUTATED	3	1	0
GEFT WILD-TYPE	193	189	268

'GEFT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.189 (Fisher's exact test), Q value = 0.85

Table S1240. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GEFT MUTATED	1	2	0	0
GEFT WILD-TYPE	135	105	183	83

'GEFT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.152 (Fisher's exact test), Q value = 0.78

Table S1241. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GEFT MUTATED	1	0	2
GEFT WILD-TYPE	221	184	101

'GEFT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S1242. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GEFT MUTATED	2	0	1
GEFT WILD-TYPE	182	162	158

'GEFT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.439 (Fisher's exact test), Q value = 1

Table S1243. Gene #110: 'GEFT MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GEFT MUTATED	1	0	1	1
GEFT WILD-TYPE	89	138	187	88

'POM121 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S1244. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
POM121 MUTATED	1	5	0
POM121 WILD-TYPE	294	476	7

'POM121 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.314 (Fisher's exact test), Q value = 0.98

Table S1245. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
POM121 MUTATED	2	1	1	0
POM121 WILD-TYPE	158	231	63	166

'POM121 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 0.95

Table S1246. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
POM121 MUTATED	3	1	0
POM121 WILD-TYPE	192	185	189

'POM121 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.74

Table S1247. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
POM121 MUTATED	3	0	1
POM121 WILD-TYPE	201	219	146

'POM121 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S1248. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
POM121 MUTATED	3	1	1
POM121 WILD-TYPE	224	234	191

'POM121 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S1249. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
POM121 MUTATED	2	2	1
POM121 WILD-TYPE	194	188	267

'POM121 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.592 (Fisher's exact test), Q value = 1

Table S1250. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
POM121 MUTATED	1	2	1	0
POM121 WILD-TYPE	135	105	182	83

'POM121 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S1251. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
POM121 MUTATED	1	1	2
POM121 WILD-TYPE	221	183	101

'POM121 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S1252. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
POM121 MUTATED	1	1	2
POM121 WILD-TYPE	183	161	157

'POM121 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.523 (Fisher's exact test), Q value = 1

Table S1253. Gene #111: 'POM121 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
POM121 MUTATED	1	0	2	1
POM121 WILD-TYPE	89	138	186	88

'CMA1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1254. Gene #112: 'CMA1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CMA1 MUTATED	1	2	0
CMA1 WILD-TYPE	294	479	7

'CMA1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.548 (Fisher's exact test), Q value = 1

Table S1255. Gene #112: 'CMA1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CMA1 MUTATED	2	1	0	0
CMA1 WILD-TYPE	158	231	64	166

'CMA1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1256. Gene #112: 'CMA1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CMA1 MUTATED	1	1	1
CMA1 WILD-TYPE	194	185	188

'CMA1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1257. Gene #112: 'CMA1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CMA1 MUTATED	1	1	1
CMA1 WILD-TYPE	203	218	146

'QKI MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.266 (Fisher's exact test), Q value = 0.95

Table S1258. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
QKI MUTATED	3	1	0	1
QKI WILD-TYPE	66	42	74	53

'QKI MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.059 (Fisher's exact test), Q value = 0.46

Table S1259. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
QKI MUTATED	4	0	0	1
QKI WILD-TYPE	59	50	48	78

'QKI MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.764 (Fisher's exact test), Q value = 1

Table S1260. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
QKI MUTATED	1	2	0	2
QKI WILD-TYPE	76	91	45	58

'QKI MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1261. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
QKI MUTATED	3	1	1
QKI WILD-TYPE	135	60	75

'QKI MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00734 (Fisher's exact test), Q value = 0.13

Table S1262. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
QKI MUTATED	4	1	1
QKI WILD-TYPE	291	480	6

Figure S233. Get High-res Image Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'QKI MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.313 (Fisher's exact test), Q value = 0.98

Table S1263. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
QKI MUTATED	2	1	1	0
QKI WILD-TYPE	158	231	63	166

'QKI MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1264. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
QKI MUTATED	2	1	1
QKI WILD-TYPE	193	185	188

'QKI MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.569 (Fisher's exact test), Q value = 1

Table S1265. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
QKI MUTATED	1	1	2
QKI WILD-TYPE	203	218	145

'QKI MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1266. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
QKI MUTATED	2	1	0
QKI WILD-TYPE	225	234	192

'QKI MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.272 (Fisher's exact test), Q value = 0.95

Table S1267. Gene #113: 'QKI MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
QKI MUTATED	2	1	0
QKI WILD-TYPE	194	189	268

'TMPRSS6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S1268. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TMPRSS6 MUTATED	2	0	3	1
TMPRSS6 WILD-TYPE	67	43	71	53

'TMPRSS6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S1269. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TMPRSS6 MUTATED	3	1	1	1
TMPRSS6 WILD-TYPE	60	49	47	78

'TMPRSS6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.662 (Fisher's exact test), Q value = 1

Table S1270. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TMPRSS6 MUTATED	3	1	1	1
TMPRSS6 WILD-TYPE	74	92	44	59

'TMPRSS6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.267 (Fisher's exact test), Q value = 0.95

Table S1271. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TMPRSS6 MUTATED	2	3	1
TMPRSS6 WILD-TYPE	136	58	75

'TMPRSS6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.05 (Fisher's exact test), Q value = 0.43

Table S1272. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TMPRSS6 MUTATED	7	2	0
TMPRSS6 WILD-TYPE	288	479	7

'TMPRSS6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0237 (Fisher's exact test), Q value = 0.27

Table S1273. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TMPRSS6 MUTATED	5	1	0	0
TMPRSS6 WILD-TYPE	155	231	64	166

Figure S234. Get High-res Image Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'TMPRSS6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 0.89

Table S1274. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TMPRSS6 MUTATED	5	1	1
TMPRSS6 WILD-TYPE	190	185	188

'TMPRSS6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.67

Table S1275. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TMPRSS6 MUTATED	5	2	0
TMPRSS6 WILD-TYPE	199	217	147

'TMPRSS6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00152 (Fisher's exact test), Q value = 0.037

Table S1276. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TMPRSS6 MUTATED	8	1	0
TMPRSS6 WILD-TYPE	219	234	192

Figure S235. Get High-res Image Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'TMPRSS6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00695 (Fisher's exact test), Q value = 0.13

Table S1277. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TMPRSS6 MUTATED	6	3	0
TMPRSS6 WILD-TYPE	190	187	268

Figure S236. Get High-res Image Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S1278. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TMPRSS6 MUTATED	1	2	0	0
TMPRSS6 WILD-TYPE	135	105	183	83

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.153 (Fisher's exact test), Q value = 0.78

Table S1279. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TMPRSS6 MUTATED	1	0	2
TMPRSS6 WILD-TYPE	221	184	101

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S1280. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TMPRSS6 MUTATED	2	0	1
TMPRSS6 WILD-TYPE	182	162	158

'TMPRSS6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S1281. Gene #114: 'TMPRSS6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TMPRSS6 MUTATED	1	0	1	1
TMPRSS6 WILD-TYPE	89	138	187	88

'PLXNA3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.386 (Fisher's exact test), Q value = 1

Table S1282. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PLXNA3 MUTATED	2	8	0
PLXNA3 WILD-TYPE	293	473	7

'PLXNA3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.352 (Fisher's exact test), Q value = 1

Table S1283. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PLXNA3 MUTATED	2	2	2	4
PLXNA3 WILD-TYPE	158	230	62	162

'PLXNA3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0907 (Fisher's exact test), Q value = 0.59

Table S1284. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PLXNA3 MUTATED	7	1	2
PLXNA3 WILD-TYPE	188	185	187

'PLXNA3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S1285. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PLXNA3 MUTATED	5	4	1
PLXNA3 WILD-TYPE	199	215	146

'PLXNA3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.438 (Fisher's exact test), Q value = 1

Table S1286. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PLXNA3 MUTATED	4	5	1
PLXNA3 WILD-TYPE	223	230	191

'PLXNA3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S1287. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PLXNA3 MUTATED	3	4	3
PLXNA3 WILD-TYPE	193	186	265

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.351 (Fisher's exact test), Q value = 1

Table S1288. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PLXNA3 MUTATED	3	3	1	2
PLXNA3 WILD-TYPE	133	104	182	81

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.23 (Fisher's exact test), Q value = 0.9

Table S1289. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PLXNA3 MUTATED	5	1	3
PLXNA3 WILD-TYPE	217	183	100

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.482 (Fisher's exact test), Q value = 1

Table S1290. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PLXNA3 MUTATED	4	4	1
PLXNA3 WILD-TYPE	180	158	158

'PLXNA3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.877 (Fisher's exact test), Q value = 1

Table S1291. Gene #115: 'PLXNA3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PLXNA3 MUTATED	1	3	3	2
PLXNA3 WILD-TYPE	89	135	185	87

'EPS8L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S1292. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
EPS8L1 MUTATED	2	2	0
EPS8L1 WILD-TYPE	293	479	7

'EPS8L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.547 (Fisher's exact test), Q value = 1

Table S1293. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
EPS8L1 MUTATED	2	1	0	0
EPS8L1 WILD-TYPE	158	231	64	166

'EPS8L1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.109 (Fisher's exact test), Q value = 0.65

Table S1294. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
EPS8L1 MUTATED	3	0	0
EPS8L1 WILD-TYPE	192	186	189

'EPS8L1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0615 (Fisher's exact test), Q value = 0.47

Table S1295. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
EPS8L1 MUTATED	3	0	0
EPS8L1 WILD-TYPE	201	219	147

'EPS8L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S1296. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
EPS8L1 MUTATED	2	0	1
EPS8L1 WILD-TYPE	225	235	191

'EPS8L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1297. Gene #116: 'EPS8L1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
EPS8L1 MUTATED	1	1	1
EPS8L1 WILD-TYPE	195	189	267

'PRG4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.393 (Fisher's exact test), Q value = 1

Table S1298. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PRG4 MUTATED	2	8	0
PRG4 WILD-TYPE	293	473	7

'PRG4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1299. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PRG4 MUTATED	2	4	1	3
PRG4 WILD-TYPE	158	228	63	163

'PRG4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0703 (Fisher's exact test), Q value = 0.51

Table S1300. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PRG4 MUTATED	3	5	0
PRG4 WILD-TYPE	192	181	189

'PRG4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S1301. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PRG4 MUTATED	1	4	3
PRG4 WILD-TYPE	203	215	144

'PRG4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.329 (Fisher's exact test), Q value = 1

Table S1302. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PRG4 MUTATED	1	4	4
PRG4 WILD-TYPE	226	231	188

'PRG4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S1303. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PRG4 MUTATED	1	5	3
PRG4 WILD-TYPE	195	185	265

'PRG4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.404 (Fisher's exact test), Q value = 1

Table S1304. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PRG4 MUTATED	4	2	2	0
PRG4 WILD-TYPE	132	105	181	83

'PRG4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.901 (Fisher's exact test), Q value = 1

Table S1305. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PRG4 MUTATED	3	3	2
PRG4 WILD-TYPE	219	181	101

'PRG4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1306. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PRG4 MUTATED	2	2	4
PRG4 WILD-TYPE	182	160	155

'PRG4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.72 (Fisher's exact test), Q value = 1

Table S1307. Gene #117: 'PRG4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PRG4 MUTATED	2	1	3	2
PRG4 WILD-TYPE	88	137	185	87

'RFX4 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1308. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
RFX4 MUTATED	2	4	0
RFX4 WILD-TYPE	293	477	7

'RFX4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.209 (Fisher's exact test), Q value = 0.86

Table S1309. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
RFX4 MUTATED	2	0	1	2
RFX4 WILD-TYPE	158	232	63	164

'RFX4 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.279 (Fisher's exact test), Q value = 0.95

Table S1310. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
RFX4 MUTATED	3	1	0
RFX4 WILD-TYPE	192	185	189

'RFX4 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.836 (Fisher's exact test), Q value = 1

Table S1311. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
RFX4 MUTATED	2	1	1
RFX4 WILD-TYPE	202	218	146

'RFX4 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1312. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
RFX4 MUTATED	1	2	1
RFX4 WILD-TYPE	226	233	191

'RFX4 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.98

Table S1313. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
RFX4 MUTATED	0	1	3
RFX4 WILD-TYPE	196	189	265

'RFX4 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1314. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RFX4 MUTATED	0	1	2	1
RFX4 WILD-TYPE	136	106	181	82

'RFX4 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.684 (Fisher's exact test), Q value = 1

Table S1315. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RFX4 MUTATED	1	2	1
RFX4 WILD-TYPE	221	182	102

'RFX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S1316. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RFX4 MUTATED	0	2	2
RFX4 WILD-TYPE	184	160	157

'RFX4 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.759 (Fisher's exact test), Q value = 1

Table S1317. Gene #118: 'RFX4 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RFX4 MUTATED	0	2	2	0
RFX4 WILD-TYPE	90	136	186	89

'MYT1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.137 (Fisher's exact test), Q value = 0.74

Table S1318. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MYT1 MUTATED	0	6	0
MYT1 WILD-TYPE	295	475	7

'MYT1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.267 (Fisher's exact test), Q value = 0.95

Table S1319. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MYT1 MUTATED	1	4	1	0
MYT1 WILD-TYPE	159	228	63	166

'MYT1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.879 (Fisher's exact test), Q value = 1

Table S1320. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MYT1 MUTATED	2	3	1
MYT1 WILD-TYPE	225	232	191

'MYT1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.018 (Fisher's exact test), Q value = 0.23

Table S1321. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MYT1 MUTATED	0	5	1
MYT1 WILD-TYPE	196	185	267

Figure S237. Get High-res Image Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'MYT1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.427 (Fisher's exact test), Q value = 1

Table S1322. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MYT1 MUTATED	0	2	3	1
MYT1 WILD-TYPE	136	105	180	82

'MYT1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.755 (Fisher's exact test), Q value = 1

Table S1323. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MYT1 MUTATED	2	2	2
MYT1 WILD-TYPE	220	182	101

'MYT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.451 (Fisher's exact test), Q value = 1

Table S1324. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MYT1 MUTATED	1	2	3
MYT1 WILD-TYPE	183	160	156

'MYT1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.942 (Fisher's exact test), Q value = 1

Table S1325. Gene #119: 'MYT1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MYT1 MUTATED	1	1	3	1
MYT1 WILD-TYPE	89	137	185	88

'GFRA4 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.572 (Fisher's exact test), Q value = 1

Table S1326. Gene #120: 'GFRA4 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
GFRA4 MUTATED	2	1	0
GFRA4 WILD-TYPE	293	480	7

'GFRA4 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.546 (Fisher's exact test), Q value = 1

Table S1327. Gene #120: 'GFRA4 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
GFRA4 MUTATED	2	1	0	0
GFRA4 WILD-TYPE	158	231	64	166

'PASD1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.286 (Fisher's exact test), Q value = 0.97

Table S1328. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PASD1 MUTATED	3	1	0	0
PASD1 WILD-TYPE	74	92	45	60

'PASD1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.00768 (Fisher's exact test), Q value = 0.13

Table S1329. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PASD1 MUTATED	0	0	4
PASD1 WILD-TYPE	138	61	72

Figure S238. Get High-res Image Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

'PASD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S1330. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PASD1 MUTATED	4	4	0
PASD1 WILD-TYPE	291	477	7

'PASD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1331. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
PASD1 MUTATED	3	2	0	2
PASD1 WILD-TYPE	157	230	64	164

'PASD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.9 (Fisher's exact test), Q value = 1

Table S1332. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PASD1 MUTATED	2	2	3
PASD1 WILD-TYPE	193	184	186

'PASD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.897 (Fisher's exact test), Q value = 1

Table S1333. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PASD1 MUTATED	3	2	2
PASD1 WILD-TYPE	201	217	145

'PASD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.65

Table S1334. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PASD1 MUTATED	0	1	3
PASD1 WILD-TYPE	227	234	189

'PASD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.98

Table S1335. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PASD1 MUTATED	0	1	3
PASD1 WILD-TYPE	196	189	265

'PASD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.914 (Fisher's exact test), Q value = 1

Table S1336. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
PASD1 MUTATED	1	1	1	1
PASD1 WILD-TYPE	135	106	182	82

'PASD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.423 (Fisher's exact test), Q value = 1

Table S1337. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
PASD1 MUTATED	1	3	0
PASD1 WILD-TYPE	221	181	103

'PASD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0755 (Fisher's exact test), Q value = 0.53

Table S1338. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
PASD1 MUTATED	0	1	3
PASD1 WILD-TYPE	184	161	156

'PASD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.758 (Fisher's exact test), Q value = 1

Table S1339. Gene #121: 'PASD1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
PASD1 MUTATED	0	2	2	0
PASD1 WILD-TYPE	90	136	186	89

'TNFRSF9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S1340. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TNFRSF9 MUTATED	2	2	0
TNFRSF9 WILD-TYPE	293	479	7

'TNFRSF9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0671 (Fisher's exact test), Q value = 0.49

Table S1341. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TNFRSF9 MUTATED	1	1	2	0
TNFRSF9 WILD-TYPE	159	231	62	166

'TNFRSF9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S1342. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TNFRSF9 MUTATED	1	2	1
TNFRSF9 WILD-TYPE	194	184	188

'TNFRSF9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.57 (Fisher's exact test), Q value = 1

Table S1343. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TNFRSF9 MUTATED	1	1	2
TNFRSF9 WILD-TYPE	203	218	145

'TNFRSF9 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1344. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TNFRSF9 MUTATED	1	1	1
TNFRSF9 WILD-TYPE	226	234	191

'TNFRSF9 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1345. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TNFRSF9 MUTATED	1	1	1
TNFRSF9 WILD-TYPE	195	189	267

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.599 (Fisher's exact test), Q value = 1

Table S1346. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TNFRSF9 MUTATED	2	0	1	0
TNFRSF9 WILD-TYPE	134	107	182	83

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S1347. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TNFRSF9 MUTATED	1	1	1
TNFRSF9 WILD-TYPE	221	183	102

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S1348. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TNFRSF9 MUTATED	2	0	1
TNFRSF9 WILD-TYPE	182	162	158

'TNFRSF9 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.512 (Fisher's exact test), Q value = 1

Table S1349. Gene #122: 'TNFRSF9 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TNFRSF9 MUTATED	0	0	2	1
TNFRSF9 WILD-TYPE	90	138	186	88

'EGR1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.701 (Fisher's exact test), Q value = 1

Table S1350. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
EGR1 MUTATED	2	0	1	0
EGR1 WILD-TYPE	67	43	73	54

'EGR1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.785 (Fisher's exact test), Q value = 1

Table S1351. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
EGR1 MUTATED	1	0	0	2
EGR1 WILD-TYPE	62	50	48	77

'EGR1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.24 (Fisher's exact test), Q value = 0.91

Table S1352. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
EGR1 MUTATED	1	0	0	2
EGR1 WILD-TYPE	76	93	45	58

'EGR1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.195 (Fisher's exact test), Q value = 0.85

Table S1353. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
EGR1 MUTATED	1	2	0
EGR1 WILD-TYPE	137	59	76

'EGR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1354. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
EGR1 MUTATED	2	3	0
EGR1 WILD-TYPE	293	478	7

'EGR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.65

Table S1355. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
EGR1 MUTATED	3	0	0
EGR1 WILD-TYPE	192	186	189

'EGR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.064 (Fisher's exact test), Q value = 0.48

Table S1356. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
EGR1 MUTATED	3	0	0
EGR1 WILD-TYPE	201	219	147

'EGR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 0.79

Table S1357. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
EGR1 MUTATED	3	0	1
EGR1 WILD-TYPE	224	235	191

'EGR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1358. Gene #123: 'EGR1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
EGR1 MUTATED	2	1	1
EGR1 WILD-TYPE	194	189	267

'FAM126B MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S1359. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
FAM126B MUTATED	1	0	3	0
FAM126B WILD-TYPE	68	43	71	54

'FAM126B MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0293 (Fisher's exact test), Q value = 0.3

Table S1360. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FAM126B MUTATED	1	0	3	0
FAM126B WILD-TYPE	62	50	45	79

Figure S239. Get High-res Image Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

'FAM126B MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1361. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
FAM126B MUTATED	2	2	0	0
FAM126B WILD-TYPE	75	91	45	60

'FAM126B MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.443 (Fisher's exact test), Q value = 1

Table S1362. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FAM126B MUTATED	1	1	2
FAM126B WILD-TYPE	137	60	74

'FAM126B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0365 (Fisher's exact test), Q value = 0.36

Table S1363. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
FAM126B MUTATED	4	3	1
FAM126B WILD-TYPE	291	478	6

Figure S240. Get High-res Image Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FAM126B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S1364. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
FAM126B MUTATED	2	1	0	1
FAM126B WILD-TYPE	158	231	64	165

'FAM126B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.705 (Fisher's exact test), Q value = 1

Table S1365. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
FAM126B MUTATED	2	1	3
FAM126B WILD-TYPE	193	185	186

'FAM126B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.771 (Fisher's exact test), Q value = 1

Table S1366. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
FAM126B MUTATED	3	2	1
FAM126B WILD-TYPE	201	217	146

'FAM126B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.272 (Fisher's exact test), Q value = 0.95

Table S1367. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
FAM126B MUTATED	3	1	0
FAM126B WILD-TYPE	224	234	192

'FAM126B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.694 (Fisher's exact test), Q value = 1

Table S1368. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
FAM126B MUTATED	1	2	1
FAM126B WILD-TYPE	195	188	267

'FAM126B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.196 (Fisher's exact test), Q value = 0.85

Table S1369. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FAM126B MUTATED	1	2	0	1
FAM126B WILD-TYPE	135	105	183	82

'FAM126B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.85

Table S1370. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FAM126B MUTATED	2	0	2
FAM126B WILD-TYPE	220	184	101

'FAM126B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S1371. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FAM126B MUTATED	1	2	1
FAM126B WILD-TYPE	183	160	158

'FAM126B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.697 (Fisher's exact test), Q value = 1

Table S1372. Gene #124: 'FAM126B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FAM126B MUTATED	1	2	1	0
FAM126B WILD-TYPE	89	136	187	89

'SON MUTATION STATUS' versus 'CN_CNMF'

P value = 0.536 (Fisher's exact test), Q value = 1

Table S1373. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SON MUTATED	2	7	0
SON WILD-TYPE	293	474	7

'SON MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S1374. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SON MUTATED	4	2	0	2
SON WILD-TYPE	156	230	64	164

'SON MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.231 (Fisher's exact test), Q value = 0.9

Table S1375. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SON MUTATED	5	1	1
SON WILD-TYPE	190	185	188

'SON MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.394 (Fisher's exact test), Q value = 1

Table S1376. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SON MUTATED	4	1	2
SON WILD-TYPE	200	218	145

'SON MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1377. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SON MUTATED	4	3	2
SON WILD-TYPE	223	232	190

'SON MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S1378. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SON MUTATED	3	3	3
SON WILD-TYPE	193	187	265

'SON MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.826 (Fisher's exact test), Q value = 1

Table S1379. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SON MUTATED	2	2	2	2
SON WILD-TYPE	134	105	181	81

'SON MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S1380. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SON MUTATED	3	2	3
SON WILD-TYPE	219	182	100

'SON MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.643 (Fisher's exact test), Q value = 1

Table S1381. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SON MUTATED	3	1	3
SON WILD-TYPE	181	161	156

'SON MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.16 (Fisher's exact test), Q value = 0.8

Table S1382. Gene #125: 'SON MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SON MUTATED	1	0	3	3
SON WILD-TYPE	89	138	185	86

'AMPD1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.361 (Fisher's exact test), Q value = 1

Table S1383. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
AMPD1 MUTATED	0	1	2	0
AMPD1 WILD-TYPE	69	42	72	54

'AMPD1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 0.95

Table S1384. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
AMPD1 MUTATED	2	0	1	0
AMPD1 WILD-TYPE	61	50	47	79

'AMPD1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.686 (Fisher's exact test), Q value = 1

Table S1385. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
AMPD1 MUTATED	2	1	0	0
AMPD1 WILD-TYPE	75	92	45	60

'AMPD1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.198 (Fisher's exact test), Q value = 0.85

Table S1386. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
AMPD1 MUTATED	1	2	0
AMPD1 WILD-TYPE	137	59	76

'AMPD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.47 (Fisher's exact test), Q value = 1

Table S1387. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
AMPD1 MUTATED	4	3	0
AMPD1 WILD-TYPE	291	478	7

'AMPD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.139 (Fisher's exact test), Q value = 0.74

Table S1388. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
AMPD1 MUTATED	4	2	0	0
AMPD1 WILD-TYPE	156	230	64	166

'AMPD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.549 (Fisher's exact test), Q value = 1

Table S1389. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
AMPD1 MUTATED	1	0	2
AMPD1 WILD-TYPE	194	186	187

'AMPD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.629 (Fisher's exact test), Q value = 1

Table S1390. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
AMPD1 MUTATED	2	1	0
AMPD1 WILD-TYPE	202	218	147

'AMPD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.353 (Fisher's exact test), Q value = 1

Table S1391. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
AMPD1 MUTATED	4	1	2
AMPD1 WILD-TYPE	223	234	190

'AMPD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S1392. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
AMPD1 MUTATED	3	2	2
AMPD1 WILD-TYPE	193	188	266

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S1393. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AMPD1 MUTATED	0	2	2	0
AMPD1 WILD-TYPE	136	105	181	83

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.341 (Fisher's exact test), Q value = 1

Table S1394. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AMPD1 MUTATED	1	1	2
AMPD1 WILD-TYPE	221	183	101

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.8

Table S1395. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AMPD1 MUTATED	1	0	3
AMPD1 WILD-TYPE	183	162	156

'AMPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.919 (Fisher's exact test), Q value = 1

Table S1396. Gene #126: 'AMPD1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AMPD1 MUTATED	0	1	2	1
AMPD1 WILD-TYPE	90	137	186	88

'TNFSF9 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S1397. Gene #127: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TNFSF9 MUTATED	2	1	0	0
TNFSF9 WILD-TYPE	75	92	45	60

'TNFSF9 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.311 (Fisher's exact test), Q value = 0.98

Table S1398. Gene #127: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TNFSF9 MUTATED	1	0	2
TNFSF9 WILD-TYPE	137	61	74

'TNFSF9 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.402 (Fisher's exact test), Q value = 1

Table S1399. Gene #127: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TNFSF9 MUTATED	3	2	0
TNFSF9 WILD-TYPE	292	479	7

'TNFSF9 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S1400. Gene #127: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TNFSF9 MUTATED	3	1	0	1
TNFSF9 WILD-TYPE	157	231	64	165

'TNFSF9 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.338 (Fisher's exact test), Q value = 1

Table S1401. Gene #127: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TNFSF9 MUTATED	2	0	3
TNFSF9 WILD-TYPE	193	186	186

'TNFSF9 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S1402. Gene #127: 'TNFSF9 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TNFSF9 MUTATED	2	3	0
TNFSF9 WILD-TYPE	202	216	147

'MYH11 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1403. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
MYH11 MUTATED	1	1	2	1
MYH11 WILD-TYPE	68	42	72	53

'MYH11 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.478 (Fisher's exact test), Q value = 1

Table S1404. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MYH11 MUTATED	0	2	1	2
MYH11 WILD-TYPE	63	48	47	77

'MYH11 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0755 (Fisher's exact test), Q value = 0.53

Table S1405. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
MYH11 MUTATED	1	1	3	0
MYH11 WILD-TYPE	76	92	42	60

'MYH11 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.516 (Fisher's exact test), Q value = 1

Table S1406. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MYH11 MUTATED	4	0	1
MYH11 WILD-TYPE	134	61	75

'MYH11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S1407. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MYH11 MUTATED	6	8	0
MYH11 WILD-TYPE	289	473	7

'MYH11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.936 (Fisher's exact test), Q value = 1

Table S1408. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MYH11 MUTATED	3	3	1	3
MYH11 WILD-TYPE	157	229	63	163

'MYH11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0439 (Fisher's exact test), Q value = 0.41

Table S1409. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MYH11 MUTATED	6	3	0
MYH11 WILD-TYPE	189	183	189

Figure S241. Get High-res Image Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'MYH11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1410. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MYH11 MUTATED	3	4	2
MYH11 WILD-TYPE	201	215	145

'MYH11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.925 (Fisher's exact test), Q value = 1

Table S1411. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MYH11 MUTATED	4	3	3
MYH11 WILD-TYPE	223	232	189

'MYH11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.616 (Fisher's exact test), Q value = 1

Table S1412. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MYH11 MUTATED	3	4	3
MYH11 WILD-TYPE	193	186	265

'MYH11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1413. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MYH11 MUTATED	2	2	4	1
MYH11 WILD-TYPE	134	105	179	82

'MYH11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.614 (Fisher's exact test), Q value = 1

Table S1414. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MYH11 MUTATED	3	3	3
MYH11 WILD-TYPE	219	181	100

'MYH11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.587 (Fisher's exact test), Q value = 1

Table S1415. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MYH11 MUTATED	2	3	4
MYH11 WILD-TYPE	182	159	155

'MYH11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.606 (Fisher's exact test), Q value = 1

Table S1416. Gene #128: 'MYH11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MYH11 MUTATED	0	3	4	2
MYH11 WILD-TYPE	90	135	184	87

'FMR1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.85

Table S1417. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
FMR1 MUTATED	0	5	0
FMR1 WILD-TYPE	295	476	7

'FMR1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1418. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
FMR1 MUTATED	1	2	1	1
FMR1 WILD-TYPE	159	230	63	165

'FMR1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.748 (Fisher's exact test), Q value = 1

Table S1419. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
FMR1 MUTATED	1	2	2
FMR1 WILD-TYPE	194	184	187

'FMR1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1420. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
FMR1 MUTATED	2	2	1
FMR1 WILD-TYPE	202	217	146

'FMR1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S1421. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
FMR1 MUTATED	3	2	0
FMR1 WILD-TYPE	224	233	192

'FMR1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.00189 (Fisher's exact test), Q value = 0.044

Table S1422. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
FMR1 MUTATED	0	5	0
FMR1 WILD-TYPE	196	185	268

Figure S242. Get High-res Image Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'FMR1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 0.92

Table S1423. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FMR1 MUTATED	1	3	1	0
FMR1 WILD-TYPE	135	104	182	83

'FMR1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.355 (Fisher's exact test), Q value = 1

Table S1424. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FMR1 MUTATED	1	2	2
FMR1 WILD-TYPE	221	182	101

'FMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S1425. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FMR1 MUTATED	3	0	2
FMR1 WILD-TYPE	181	162	157

'FMR1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1426. Gene #129: 'FMR1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FMR1 MUTATED	1	1	2	1
FMR1 WILD-TYPE	89	137	186	88

'SOX13 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S1427. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
SOX13 MUTATED	1	1	1	0
SOX13 WILD-TYPE	76	92	44	60

'SOX13 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1428. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SOX13 MUTATED	2	0	1
SOX13 WILD-TYPE	136	61	75

'SOX13 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.112 (Fisher's exact test), Q value = 0.66

Table S1429. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SOX13 MUTATED	4	1	0
SOX13 WILD-TYPE	291	480	7

'SOX13 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0124 (Fisher's exact test), Q value = 0.19

Table S1430. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SOX13 MUTATED	4	0	0	0
SOX13 WILD-TYPE	156	232	64	166

Figure S243. Get High-res Image Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'SOX13 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.541 (Fisher's exact test), Q value = 1

Table S1431. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SOX13 MUTATED	1	1	3
SOX13 WILD-TYPE	194	185	186

'SOX13 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1432. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SOX13 MUTATED	2	2	1
SOX13 WILD-TYPE	202	217	146

'SOX13 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S1433. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SOX13 MUTATED	2	0	1
SOX13 WILD-TYPE	225	235	191

'SOX13 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1434. Gene #130: 'SOX13 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SOX13 MUTATED	1	1	1
SOX13 WILD-TYPE	195	189	267

'ANKRD36 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.307 (Fisher's exact test), Q value = 0.98

Table S1435. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ANKRD36 MUTATED	1	6	0
ANKRD36 WILD-TYPE	294	475	7

'ANKRD36 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0905 (Fisher's exact test), Q value = 0.59

Table S1436. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ANKRD36 MUTATED	1	6	0	0
ANKRD36 WILD-TYPE	159	226	64	166

'ANKRD36 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.707 (Fisher's exact test), Q value = 1

Table S1437. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ANKRD36 MUTATED	2	1	3
ANKRD36 WILD-TYPE	193	185	186

'ANKRD36 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S1438. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ANKRD36 MUTATED	1	4	1
ANKRD36 WILD-TYPE	203	215	146

'ANKRD36 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.406 (Fisher's exact test), Q value = 1

Table S1439. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ANKRD36 MUTATED	1	4	2
ANKRD36 WILD-TYPE	226	231	190

'ANKRD36 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.309 (Fisher's exact test), Q value = 0.98

Table S1440. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ANKRD36 MUTATED	1	4	2
ANKRD36 WILD-TYPE	195	186	266

'ANKRD36 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.737 (Fisher's exact test), Q value = 1

Table S1441. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ANKRD36 MUTATED	1	1	3	2
ANKRD36 WILD-TYPE	135	106	180	81

'ANKRD36 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1442. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ANKRD36 MUTATED	3	3	1
ANKRD36 WILD-TYPE	219	181	102

'ANKRD36 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.895 (Fisher's exact test), Q value = 1

Table S1443. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ANKRD36 MUTATED	2	3	2
ANKRD36 WILD-TYPE	182	159	157

'ANKRD36 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.949 (Fisher's exact test), Q value = 1

Table S1444. Gene #131: 'ANKRD36 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ANKRD36 MUTATED	1	3	2	1
ANKRD36 WILD-TYPE	89	135	186	88

'KLKB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.732 (Fisher's exact test), Q value = 1

Table S1445. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KLKB1 MUTATED	2	5	0
KLKB1 WILD-TYPE	293	476	7

'KLKB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S1446. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KLKB1 MUTATED	1	3	0	1
KLKB1 WILD-TYPE	159	229	64	165

'KLKB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.78

Table S1447. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
KLKB1 MUTATED	4	2	0
KLKB1 WILD-TYPE	191	184	189

'KLKB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1448. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
KLKB1 MUTATED	2	2	2
KLKB1 WILD-TYPE	202	217	145

'KLKB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1449. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KLKB1 MUTATED	2	2	2
KLKB1 WILD-TYPE	225	233	190

'KLKB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.593 (Fisher's exact test), Q value = 1

Table S1450. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KLKB1 MUTATED	1	3	2
KLKB1 WILD-TYPE	195	187	266

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.928 (Fisher's exact test), Q value = 1

Table S1451. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KLKB1 MUTATED	2	1	2	0
KLKB1 WILD-TYPE	134	106	181	83

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1452. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KLKB1 MUTATED	2	2	1
KLKB1 WILD-TYPE	220	182	102

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.243 (Fisher's exact test), Q value = 0.92

Table S1453. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KLKB1 MUTATED	2	0	3
KLKB1 WILD-TYPE	182	162	156

'KLKB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1454. Gene #132: 'KLKB1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KLKB1 MUTATED	1	1	3	0
KLKB1 WILD-TYPE	89	137	185	89

'ST3GAL6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1455. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ST3GAL6 MUTATED	3	2	0
ST3GAL6 WILD-TYPE	292	479	7

'ST3GAL6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.97

Table S1456. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ST3GAL6 MUTATED	2	0	0	1
ST3GAL6 WILD-TYPE	158	232	64	165

'ST3GAL6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.226 (Fisher's exact test), Q value = 0.89

Table S1457. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ST3GAL6 MUTATED	1	0	3
ST3GAL6 WILD-TYPE	194	186	186

'ST3GAL6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0206 (Fisher's exact test), Q value = 0.26

Table S1458. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ST3GAL6 MUTATED	4	0	0
ST3GAL6 WILD-TYPE	200	219	147

Figure S244. Get High-res Image Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'ST3GAL6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0592 (Fisher's exact test), Q value = 0.46

Table S1459. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ST3GAL6 MUTATED	4	0	1
ST3GAL6 WILD-TYPE	223	235	191

'ST3GAL6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.525 (Fisher's exact test), Q value = 1

Table S1460. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ST3GAL6 MUTATED	3	1	1
ST3GAL6 WILD-TYPE	193	189	267

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1461. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ST3GAL6 MUTATED	1	1	1	0
ST3GAL6 WILD-TYPE	135	106	182	83

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0523 (Fisher's exact test), Q value = 0.43

Table S1462. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ST3GAL6 MUTATED	0	1	2
ST3GAL6 WILD-TYPE	222	183	101

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.411 (Fisher's exact test), Q value = 1

Table S1463. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ST3GAL6 MUTATED	1	0	2
ST3GAL6 WILD-TYPE	183	162	157

'ST3GAL6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 0.78

Table S1464. Gene #133: 'ST3GAL6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ST3GAL6 MUTATED	0	0	1	2
ST3GAL6 WILD-TYPE	90	138	187	87

'HTT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.85

Table S1465. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
HTT MUTATED	0	5	0
HTT WILD-TYPE	295	476	7

'HTT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0487 (Fisher's exact test), Q value = 0.42

Table S1466. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
HTT MUTATED	1	0	0	4
HTT WILD-TYPE	159	232	64	162

Figure S245. Get High-res Image Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'HTT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.291 (Fisher's exact test), Q value = 0.97

Table S1467. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
HTT MUTATED	3	2	0
HTT WILD-TYPE	192	184	189

'HTT MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.852 (Fisher's exact test), Q value = 1

Table S1468. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
HTT MUTATED	1	2	2
HTT WILD-TYPE	203	217	145

'HTT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.169 (Fisher's exact test), Q value = 0.81

Table S1469. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
HTT MUTATED	2	0	3
HTT WILD-TYPE	225	235	189

'HTT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S1470. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
HTT MUTATED	0	2	3
HTT WILD-TYPE	196	188	265

'HTT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.264 (Fisher's exact test), Q value = 0.95

Table S1471. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
HTT MUTATED	0	2	3	0
HTT WILD-TYPE	136	105	180	83

'HTT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0231 (Fisher's exact test), Q value = 0.27

Table S1472. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
HTT MUTATED	0	2	3
HTT WILD-TYPE	222	182	100

Figure S246. Get High-res Image Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'HTT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.454 (Fisher's exact test), Q value = 1

Table S1473. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
HTT MUTATED	1	1	3
HTT WILD-TYPE	183	161	156

'HTT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S1474. Gene #134: 'HTT MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
HTT MUTATED	0	1	3	1
HTT WILD-TYPE	90	137	185	88

'AK7 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.138 (Fisher's exact test), Q value = 0.74

Table S1475. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
AK7 MUTATED	0	0	2	3
AK7 WILD-TYPE	69	43	72	51

'AK7 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.127 (Fisher's exact test), Q value = 0.69

Table S1476. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
AK7 MUTATED	0	0	1	4
AK7 WILD-TYPE	63	50	47	75

'AK7 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S1477. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
AK7 MUTATED	1	3	1	0
AK7 WILD-TYPE	76	90	44	60

'AK7 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.235 (Fisher's exact test), Q value = 0.9

Table S1478. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
AK7 MUTATED	2	0	3
AK7 WILD-TYPE	136	61	73

'AK7 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0513 (Fisher's exact test), Q value = 0.43

Table S1479. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
AK7 MUTATED	7	2	0
AK7 WILD-TYPE	288	479	7

'AK7 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0719 (Fisher's exact test), Q value = 0.51

Table S1480. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
AK7 MUTATED	4	1	0	0
AK7 WILD-TYPE	156	231	64	166

'AK7 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.804 (Fisher's exact test), Q value = 1

Table S1481. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
AK7 MUTATED	2	3	2
AK7 WILD-TYPE	193	183	187

'AK7 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.494 (Fisher's exact test), Q value = 1

Table S1482. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
AK7 MUTATED	1	4	2
AK7 WILD-TYPE	203	215	145

'AK7 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 0.81

Table S1483. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
AK7 MUTATED	5	1	1
AK7 WILD-TYPE	222	234	191

'AK7 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0861 (Fisher's exact test), Q value = 0.58

Table S1484. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
AK7 MUTATED	5	1	1
AK7 WILD-TYPE	191	189	267

'AK7 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0811 (Fisher's exact test), Q value = 0.56

Table S1485. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AK7 MUTATED	0	3	1	0
AK7 WILD-TYPE	136	104	182	83

'AK7 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00168 (Fisher's exact test), Q value = 0.04

Table S1486. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AK7 MUTATED	0	0	4
AK7 WILD-TYPE	222	184	99

Figure S247. Get High-res Image Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'AK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.95

Table S1487. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AK7 MUTATED	3	0	1
AK7 WILD-TYPE	181	162	158

'AK7 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0011 (Fisher's exact test), Q value = 0.028

Table S1488. Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AK7 MUTATED	0	0	0	4
AK7 WILD-TYPE	90	138	188	85

Figure S248. Get High-res Image Gene #135: 'AK7 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

'ZZZ3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1489. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZZZ3 MUTATED	1	3	0
ZZZ3 WILD-TYPE	294	478	7

'ZZZ3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S1490. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZZZ3 MUTATED	1	2	0	0
ZZZ3 WILD-TYPE	159	230	64	166

'ZZZ3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1491. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZZZ3 MUTATED	2	1	1
ZZZ3 WILD-TYPE	193	185	188

'ZZZ3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.683 (Fisher's exact test), Q value = 1

Table S1492. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZZZ3 MUTATED	2	2	0
ZZZ3 WILD-TYPE	202	217	147

'ZZZ3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.559 (Fisher's exact test), Q value = 1

Table S1493. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZZZ3 MUTATED	2	2	0
ZZZ3 WILD-TYPE	225	233	192

'ZZZ3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0717 (Fisher's exact test), Q value = 0.51

Table S1494. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZZZ3 MUTATED	1	3	0
ZZZ3 WILD-TYPE	195	187	268

'ZZZ3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.384 (Fisher's exact test), Q value = 1

Table S1495. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZZZ3 MUTATED	1	1	0	1
ZZZ3 WILD-TYPE	135	106	183	82

'ZZZ3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S1496. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZZZ3 MUTATED	2	0	1
ZZZ3 WILD-TYPE	220	184	102

'ZZZ3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.65 (Fisher's exact test), Q value = 1

Table S1497. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZZZ3 MUTATED	2	0	1
ZZZ3 WILD-TYPE	182	162	158

'ZZZ3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.887 (Fisher's exact test), Q value = 1

Table S1498. Gene #136: 'ZZZ3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZZZ3 MUTATED	1	1	1	0
ZZZ3 WILD-TYPE	89	137	187	89

'NPTX1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0357 (Fisher's exact test), Q value = 0.35

Table S1499. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NPTX1 MUTATED	2	2	1
NPTX1 WILD-TYPE	293	479	6

Figure S249. Get High-res Image Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NPTX1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.178 (Fisher's exact test), Q value = 0.84

Table S1500. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NPTX1 MUTATED	2	0	1	1
NPTX1 WILD-TYPE	158	232	63	165

'NPTX1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S1501. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NPTX1 MUTATED	2	0	1
NPTX1 WILD-TYPE	193	186	188

'NPTX1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S1502. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NPTX1 MUTATED	2	0	1
NPTX1 WILD-TYPE	202	219	146

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.274 (Fisher's exact test), Q value = 0.95

Table S1503. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NPTX1 MUTATED	3	1	0
NPTX1 WILD-TYPE	224	234	192

'NPTX1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.824 (Fisher's exact test), Q value = 1

Table S1504. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NPTX1 MUTATED	2	1	1
NPTX1 WILD-TYPE	194	189	267

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0919 (Fisher's exact test), Q value = 0.59

Table S1505. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NPTX1 MUTATED	0	2	0	1
NPTX1 WILD-TYPE	136	105	183	82

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.151 (Fisher's exact test), Q value = 0.78

Table S1506. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NPTX1 MUTATED	1	0	2
NPTX1 WILD-TYPE	221	184	101

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.652 (Fisher's exact test), Q value = 1

Table S1507. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NPTX1 MUTATED	2	0	1
NPTX1 WILD-TYPE	182	162	158

'NPTX1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S1508. Gene #138: 'NPTX1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NPTX1 MUTATED	0	0	2	1
NPTX1 WILD-TYPE	90	138	186	88

'C10ORF46 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1509. Gene #139: 'C10ORF46 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
C10ORF46 MUTATED	1	2	0
C10ORF46 WILD-TYPE	294	479	7

'C10ORF46 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1510. Gene #139: 'C10ORF46 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
C10ORF46 MUTATED	1	1	1
C10ORF46 WILD-TYPE	226	234	191

'C10ORF46 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.378 (Fisher's exact test), Q value = 1

Table S1511. Gene #139: 'C10ORF46 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
C10ORF46 MUTATED	0	2	1
C10ORF46 WILD-TYPE	196	188	267

'CHGB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.782 (Fisher's exact test), Q value = 1

Table S1512. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
CHGB MUTATED	1	0	2	0
CHGB WILD-TYPE	68	43	72	54

'CHGB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.618 (Fisher's exact test), Q value = 1

Table S1513. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CHGB MUTATED	2	0	0	1
CHGB WILD-TYPE	61	50	48	78

'CHGB MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.642 (Fisher's exact test), Q value = 1

Table S1514. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
CHGB MUTATED	2	2	0	0
CHGB WILD-TYPE	75	91	45	60

'CHGB MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.444 (Fisher's exact test), Q value = 1

Table S1515. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CHGB MUTATED	1	1	2
CHGB WILD-TYPE	137	60	74

'CHGB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.522 (Fisher's exact test), Q value = 1

Table S1516. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CHGB MUTATED	4	4	0
CHGB WILD-TYPE	291	477	7

'CHGB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.609 (Fisher's exact test), Q value = 1

Table S1517. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CHGB MUTATED	3	2	0	1
CHGB WILD-TYPE	157	230	64	165

'CHGB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.228 (Fisher's exact test), Q value = 0.89

Table S1518. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CHGB MUTATED	5	1	1
CHGB WILD-TYPE	190	185	188

'CHGB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.309 (Fisher's exact test), Q value = 0.98

Table S1519. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CHGB MUTATED	3	4	0
CHGB WILD-TYPE	201	215	147

'CHGB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1520. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CHGB MUTATED	3	2	1
CHGB WILD-TYPE	224	233	191

'CHGB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.39 (Fisher's exact test), Q value = 1

Table S1521. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CHGB MUTATED	2	3	1
CHGB WILD-TYPE	194	187	267

'CHGB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.763 (Fisher's exact test), Q value = 1

Table S1522. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CHGB MUTATED	2	1	1	0
CHGB WILD-TYPE	134	106	182	83

'CHGB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.339 (Fisher's exact test), Q value = 1

Table S1523. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CHGB MUTATED	1	1	2
CHGB WILD-TYPE	221	183	101

'CHGB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S1524. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CHGB MUTATED	1	1	2
CHGB WILD-TYPE	183	161	157

'CHGB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 0.95

Table S1525. Gene #140: 'CHGB MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CHGB MUTATED	2	0	2	0
CHGB WILD-TYPE	88	138	186	89

'MTMR12 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.187 (Fisher's exact test), Q value = 0.85

Table S1526. Gene #141: 'MTMR12 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MTMR12 MUTATED	3	1	0
MTMR12 WILD-TYPE	292	480	7

'MTMR12 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0461 (Fisher's exact test), Q value = 0.41

Table S1527. Gene #141: 'MTMR12 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MTMR12 MUTATED	3	0	0	0
MTMR12 WILD-TYPE	157	232	64	166

Figure S250. Get High-res Image Gene #141: 'MTMR12 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'MTMR12 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0221 (Fisher's exact test), Q value = 0.26

Table S1528. Gene #141: 'MTMR12 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MTMR12 MUTATED	4	0	0
MTMR12 WILD-TYPE	223	235	192

Figure S251. Get High-res Image Gene #141: 'MTMR12 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'MTMR12 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.103 (Fisher's exact test), Q value = 0.64

Table S1529. Gene #141: 'MTMR12 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MTMR12 MUTATED	3	1	0
MTMR12 WILD-TYPE	193	189	268

'CD1D MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.878 (Fisher's exact test), Q value = 1

Table S1530. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
CD1D MUTATED	1	1	1	0
CD1D WILD-TYPE	68	42	73	54

'CD1D MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1531. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CD1D MUTATED	1	1	0	1
CD1D WILD-TYPE	62	49	48	78

'CD1D MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1532. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
CD1D MUTATED	2	2	0	0
CD1D WILD-TYPE	75	91	45	60

'CD1D MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.125 (Fisher's exact test), Q value = 0.69

Table S1533. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CD1D MUTATED	1	0	3
CD1D WILD-TYPE	137	61	73

'CD1D MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0553 (Fisher's exact test), Q value = 0.44

Table S1534. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CD1D MUTATED	4	0	0
CD1D WILD-TYPE	291	481	7

'CD1D MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0472 (Fisher's exact test), Q value = 0.42

Table S1535. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CD1D MUTATED	3	0	0	0
CD1D WILD-TYPE	157	232	64	166

Figure S252. Get High-res Image Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'CD1D MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.777 (Fisher's exact test), Q value = 1

Table S1536. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CD1D MUTATED	2	0	1
CD1D WILD-TYPE	193	186	188

'CD1D MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.786 (Fisher's exact test), Q value = 1

Table S1537. Gene #142: 'CD1D MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CD1D MUTATED	1	2	0
CD1D WILD-TYPE	203	217	147

'GABRA6 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.11 (Fisher's exact test), Q value = 0.65

Table S1538. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
GABRA6 MUTATED	1	0	6	2
GABRA6 WILD-TYPE	68	43	68	52

'GABRA6 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S1539. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
GABRA6 MUTATED	1	1	3	4
GABRA6 WILD-TYPE	62	49	45	75

'GABRA6 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.142 (Fisher's exact test), Q value = 0.75

Table S1540. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
GABRA6 MUTATED	5	3	3	0
GABRA6 WILD-TYPE	72	90	42	60

'GABRA6 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.115 (Fisher's exact test), Q value = 0.67

Table S1541. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
GABRA6 MUTATED	3	2	6
GABRA6 WILD-TYPE	135	59	70

'GABRA6 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00352 (Fisher's exact test), Q value = 0.073

Table S1542. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
GABRA6 MUTATED	12	3	0
GABRA6 WILD-TYPE	283	478	7

Figure S253. Get High-res Image Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'GABRA6 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0093 (Fisher's exact test), Q value = 0.15

Table S1543. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
GABRA6 MUTATED	7	2	1	0
GABRA6 WILD-TYPE	153	230	63	166

Figure S254. Get High-res Image Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'GABRA6 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S1544. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
GABRA6 MUTATED	2	3	5
GABRA6 WILD-TYPE	193	183	184

'GABRA6 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.924 (Fisher's exact test), Q value = 1

Table S1545. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
GABRA6 MUTATED	3	4	3
GABRA6 WILD-TYPE	201	215	144

'GABRA6 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.00114 (Fisher's exact test), Q value = 0.028

Table S1546. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
GABRA6 MUTATED	9	0	2
GABRA6 WILD-TYPE	218	235	190

Figure S255. Get High-res Image Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'GABRA6 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0918 (Fisher's exact test), Q value = 0.59

Table S1547. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
GABRA6 MUTATED	7	2	2
GABRA6 WILD-TYPE	189	188	266

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S1548. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GABRA6 MUTATED	1	2	1	0
GABRA6 WILD-TYPE	135	105	182	83

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0132 (Fisher's exact test), Q value = 0.19

Table S1549. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GABRA6 MUTATED	0	1	3
GABRA6 WILD-TYPE	222	183	100

Figure S256. Get High-res Image Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.474 (Fisher's exact test), Q value = 1

Table S1550. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GABRA6 MUTATED	2	0	2
GABRA6 WILD-TYPE	182	162	157

'GABRA6 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.238 (Fisher's exact test), Q value = 0.91

Table S1551. Gene #143: 'GABRA6 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GABRA6 MUTATED	0	0	2	2
GABRA6 WILD-TYPE	90	138	186	87

'SLC2A3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.399 (Fisher's exact test), Q value = 1

Table S1552. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SLC2A3 MUTATED	3	2	0
SLC2A3 WILD-TYPE	292	479	7

'SLC2A3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.299 (Fisher's exact test), Q value = 0.97

Table S1553. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SLC2A3 MUTATED	2	0	0	1
SLC2A3 WILD-TYPE	158	232	64	165

'SLC2A3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0359 (Fisher's exact test), Q value = 0.35

Table S1554. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SLC2A3 MUTATED	4	0	0
SLC2A3 WILD-TYPE	191	186	189

Figure S257. Get High-res Image Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'SLC2A3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S1555. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SLC2A3 MUTATED	2	2	0
SLC2A3 WILD-TYPE	202	217	147

'SLC2A3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.159 (Fisher's exact test), Q value = 0.79

Table S1556. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SLC2A3 MUTATED	3	0	1
SLC2A3 WILD-TYPE	224	235	191

'SLC2A3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.823 (Fisher's exact test), Q value = 1

Table S1557. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SLC2A3 MUTATED	2	1	1
SLC2A3 WILD-TYPE	194	189	267

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0902 (Fisher's exact test), Q value = 0.59

Table S1558. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLC2A3 MUTATED	0	2	0	1
SLC2A3 WILD-TYPE	136	105	183	82

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0525 (Fisher's exact test), Q value = 0.43

Table S1559. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLC2A3 MUTATED	0	1	2
SLC2A3 WILD-TYPE	222	183	101

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1560. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLC2A3 MUTATED	1	1	1
SLC2A3 WILD-TYPE	183	161	158

'SLC2A3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.779 (Fisher's exact test), Q value = 1

Table S1561. Gene #144: 'SLC2A3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLC2A3 MUTATED	0	1	1	1
SLC2A3 WILD-TYPE	90	137	187	88

'WDR90 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.153 (Fisher's exact test), Q value = 0.78

Table S1562. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
WDR90 MUTATED	0	1	3	0
WDR90 WILD-TYPE	69	42	71	54

'WDR90 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.364 (Fisher's exact test), Q value = 1

Table S1563. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
WDR90 MUTATED	0	1	2	1
WDR90 WILD-TYPE	63	49	46	78

'WDR90 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.00944 (Fisher's exact test), Q value = 0.15

Table S1564. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
WDR90 MUTATED	0	6	0	0
WDR90 WILD-TYPE	77	87	45	60

Figure S258. Get High-res Image Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

'WDR90 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.56 (Fisher's exact test), Q value = 1

Table S1565. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
WDR90 MUTATED	4	0	2
WDR90 WILD-TYPE	134	61	74

'WDR90 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S1566. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
WDR90 MUTATED	5	4	0
WDR90 WILD-TYPE	290	477	7

'WDR90 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.509 (Fisher's exact test), Q value = 1

Table S1567. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
WDR90 MUTATED	3	1	0	2
WDR90 WILD-TYPE	157	231	64	164

'WDR90 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S1568. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
WDR90 MUTATED	3	1	3
WDR90 WILD-TYPE	192	185	186

'WDR90 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.114 (Fisher's exact test), Q value = 0.67

Table S1569. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
WDR90 MUTATED	5	2	0
WDR90 WILD-TYPE	199	217	147

'WDR90 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0425 (Fisher's exact test), Q value = 0.4

Table S1570. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
WDR90 MUTATED	5	0	2
WDR90 WILD-TYPE	222	235	190

Figure S259. Get High-res Image Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'WDR90 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.387 (Fisher's exact test), Q value = 1

Table S1571. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
WDR90 MUTATED	4	1	2
WDR90 WILD-TYPE	192	189	266

'WDR90 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.52 (Fisher's exact test), Q value = 1

Table S1572. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
WDR90 MUTATED	0	1	1	1
WDR90 WILD-TYPE	136	106	182	82

'WDR90 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1573. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
WDR90 MUTATED	1	1	1
WDR90 WILD-TYPE	221	183	102

'WDR90 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.86

Table S1574. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
WDR90 MUTATED	0	1	2
WDR90 WILD-TYPE	184	161	157

'WDR90 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1575. Gene #145: 'WDR90 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
WDR90 MUTATED	0	1	2	0
WDR90 WILD-TYPE	90	137	186	89

'REXO1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.0526 (Fisher's exact test), Q value = 0.43

Table S1576. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
REXO1 MUTATED	3	0	0	0
REXO1 WILD-TYPE	74	93	45	60

'REXO1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0704 (Fisher's exact test), Q value = 0.51

Table S1577. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
REXO1 MUTATED	0	2	1
REXO1 WILD-TYPE	138	59	75

'REXO1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.224 (Fisher's exact test), Q value = 0.89

Table S1578. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
REXO1 MUTATED	5	3	0
REXO1 WILD-TYPE	290	478	7

'REXO1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0232 (Fisher's exact test), Q value = 0.27

Table S1579. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
REXO1 MUTATED	5	1	0	0
REXO1 WILD-TYPE	155	231	64	166

Figure S260. Get High-res Image Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'REXO1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1580. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
REXO1 MUTATED	3	2	1
REXO1 WILD-TYPE	192	184	188

'REXO1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.208 (Fisher's exact test), Q value = 0.86

Table S1581. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
REXO1 MUTATED	4	2	0
REXO1 WILD-TYPE	200	217	147

'REXO1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.539 (Fisher's exact test), Q value = 1

Table S1582. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
REXO1 MUTATED	3	1	1
REXO1 WILD-TYPE	224	234	191

'REXO1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1583. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
REXO1 MUTATED	2	1	2
REXO1 WILD-TYPE	194	189	266

'REXO1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S1584. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
REXO1 MUTATED	1	1	1	1
REXO1 WILD-TYPE	135	106	182	82

'REXO1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.34 (Fisher's exact test), Q value = 1

Table S1585. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
REXO1 MUTATED	1	1	2
REXO1 WILD-TYPE	221	183	101

'REXO1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S1586. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
REXO1 MUTATED	1	1	2
REXO1 WILD-TYPE	183	161	157

'REXO1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.358 (Fisher's exact test), Q value = 1

Table S1587. Gene #146: 'REXO1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
REXO1 MUTATED	0	0	3	1
REXO1 WILD-TYPE	90	138	185	88

'TTC30B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.98

Table S1588. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TTC30B MUTATED	1	6	0
TTC30B WILD-TYPE	294	475	7

'TTC30B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S1589. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TTC30B MUTATED	1	4	0	1
TTC30B WILD-TYPE	159	228	64	165

'TTC30B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.434 (Fisher's exact test), Q value = 1

Table S1590. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TTC30B MUTATED	1	2	0
TTC30B WILD-TYPE	194	184	189

'TTC30B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.189 (Fisher's exact test), Q value = 0.85

Table S1591. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TTC30B MUTATED	1	0	2
TTC30B WILD-TYPE	203	219	145

'TTC30B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.634 (Fisher's exact test), Q value = 1

Table S1592. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TTC30B MUTATED	2	4	1
TTC30B WILD-TYPE	225	231	191

'TTC30B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.309 (Fisher's exact test), Q value = 0.98

Table S1593. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TTC30B MUTATED	1	4	2
TTC30B WILD-TYPE	195	186	266

'TTC30B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0759 (Fisher's exact test), Q value = 0.53

Table S1594. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TTC30B MUTATED	1	4	1	0
TTC30B WILD-TYPE	135	103	182	83

'TTC30B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S1595. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TTC30B MUTATED	4	1	1
TTC30B WILD-TYPE	218	183	102

'TTC30B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.452 (Fisher's exact test), Q value = 1

Table S1596. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TTC30B MUTATED	1	2	3
TTC30B WILD-TYPE	183	160	156

'TTC30B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S1597. Gene #147: 'TTC30B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TTC30B MUTATED	0	3	3	0
TTC30B WILD-TYPE	90	135	185	89

'ZMYM2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.308 (Fisher's exact test), Q value = 0.98

Table S1598. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZMYM2 MUTATED	1	6	0
ZMYM2 WILD-TYPE	294	475	7

'ZMYM2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1599. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZMYM2 MUTATED	2	2	0	3
ZMYM2 WILD-TYPE	158	230	64	163

'ZMYM2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.626 (Fisher's exact test), Q value = 1

Table S1600. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZMYM2 MUTATED	3	1	1
ZMYM2 WILD-TYPE	192	185	188

'ZMYM2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1601. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZMYM2 MUTATED	2	2	1
ZMYM2 WILD-TYPE	202	217	146

'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.798 (Fisher's exact test), Q value = 1

Table S1602. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZMYM2 MUTATED	2	2	3
ZMYM2 WILD-TYPE	225	233	189

'ZMYM2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.503 (Fisher's exact test), Q value = 1

Table S1603. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZMYM2 MUTATED	1	3	3
ZMYM2 WILD-TYPE	195	187	265

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.122 (Fisher's exact test), Q value = 0.68

Table S1604. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZMYM2 MUTATED	0	3	4	0
ZMYM2 WILD-TYPE	136	104	179	83

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.21 (Fisher's exact test), Q value = 0.86

Table S1605. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZMYM2 MUTATED	1	4	2
ZMYM2 WILD-TYPE	221	180	101

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.269 (Fisher's exact test), Q value = 0.95

Table S1606. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZMYM2 MUTATED	1	2	4
ZMYM2 WILD-TYPE	183	160	155

'ZMYM2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.366 (Fisher's exact test), Q value = 1

Table S1607. Gene #148: 'ZMYM2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZMYM2 MUTATED	0	1	5	1
ZMYM2 WILD-TYPE	90	137	183	88

'NKPD1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0143 (Fisher's exact test), Q value = 0.2

Table S1608. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NKPD1 MUTATED	0	2	1
NKPD1 WILD-TYPE	295	479	6

Figure S261. Get High-res Image Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'NKPD1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.191 (Fisher's exact test), Q value = 0.85

Table S1609. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NKPD1 MUTATED	0	2	1	0
NKPD1 WILD-TYPE	160	230	63	166

'NKPD1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.431 (Fisher's exact test), Q value = 1

Table S1610. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NKPD1 MUTATED	1	2	0
NKPD1 WILD-TYPE	194	184	189

'NKPD1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 0.85

Table S1611. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NKPD1 MUTATED	1	0	2
NKPD1 WILD-TYPE	203	219	145

'NKPD1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1612. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NKPD1 MUTATED	1	1	1
NKPD1 WILD-TYPE	226	234	191

'NKPD1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.38 (Fisher's exact test), Q value = 1

Table S1613. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NKPD1 MUTATED	0	2	1
NKPD1 WILD-TYPE	196	188	267

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.678 (Fisher's exact test), Q value = 1

Table S1614. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NKPD1 MUTATED	0	1	2	0
NKPD1 WILD-TYPE	136	106	181	83

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S1615. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NKPD1 MUTATED	1	1	1
NKPD1 WILD-TYPE	221	183	102

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.207 (Fisher's exact test), Q value = 0.86

Table S1616. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NKPD1 MUTATED	0	1	2
NKPD1 WILD-TYPE	184	161	157

'NKPD1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1617. Gene #149: 'NKPD1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NKPD1 MUTATED	0	1	1	1
NKPD1 WILD-TYPE	90	137	187	88

'ALPK3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.649 (Fisher's exact test), Q value = 1

Table S1618. Gene #150: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ALPK3 MUTATED	2	2	0
ALPK3 WILD-TYPE	293	479	7

'ALPK3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0462 (Fisher's exact test), Q value = 0.41

Table S1619. Gene #150: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ALPK3 MUTATED	3	0	0	0
ALPK3 WILD-TYPE	157	232	64	166

Figure S262. Get High-res Image Gene #150: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'ALPK3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.658 (Fisher's exact test), Q value = 1

Table S1620. Gene #150: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ALPK3 MUTATED	2	1	0
ALPK3 WILD-TYPE	193	185	189

'ALPK3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1621. Gene #150: 'ALPK3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ALPK3 MUTATED	1	1	1
ALPK3 WILD-TYPE	203	218	146

'INF2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S1622. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
INF2 MUTATED	2	2	0
INF2 WILD-TYPE	293	479	7

'INF2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1623. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
INF2 MUTATED	1	1	0	1
INF2 WILD-TYPE	159	231	64	165

'INF2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.324 (Fisher's exact test), Q value = 1

Table S1624. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
INF2 MUTATED	0	1	2
INF2 WILD-TYPE	195	185	187

'INF2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1625. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
INF2 MUTATED	1	1	1
INF2 WILD-TYPE	203	218	146

'INF2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S1626. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
INF2 MUTATED	2	0	1
INF2 WILD-TYPE	225	235	191

'INF2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1627. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
INF2 MUTATED	1	1	1
INF2 WILD-TYPE	195	189	267

'INF2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1628. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
INF2 MUTATED	1	1	1	0
INF2 WILD-TYPE	135	106	182	83

'INF2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0527 (Fisher's exact test), Q value = 0.43

Table S1629. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
INF2 MUTATED	0	1	2
INF2 WILD-TYPE	222	183	101

'INF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1630. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
INF2 MUTATED	1	1	1
INF2 WILD-TYPE	183	161	158

'INF2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S1631. Gene #151: 'INF2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
INF2 MUTATED	0	1	1	1
INF2 WILD-TYPE	90	137	187	88

'SGOL2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S1632. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
SGOL2 MUTATED	2	0	0	1
SGOL2 WILD-TYPE	67	43	74	53

'SGOL2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S1633. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SGOL2 MUTATED	1	0	0	2
SGOL2 WILD-TYPE	62	50	48	77

'SGOL2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.457 (Fisher's exact test), Q value = 1

Table S1634. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
SGOL2 MUTATED	1	0	1	1
SGOL2 WILD-TYPE	76	93	44	59

'SGOL2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.603 (Fisher's exact test), Q value = 1

Table S1635. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SGOL2 MUTATED	2	1	0
SGOL2 WILD-TYPE	136	60	76

'SGOL2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.734 (Fisher's exact test), Q value = 1

Table S1636. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SGOL2 MUTATED	2	5	0
SGOL2 WILD-TYPE	293	476	7

'SGOL2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.849 (Fisher's exact test), Q value = 1

Table S1637. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SGOL2 MUTATED	1	3	0	1
SGOL2 WILD-TYPE	159	229	64	165

'SGOL2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.776 (Fisher's exact test), Q value = 1

Table S1638. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SGOL2 MUTATED	2	0	1
SGOL2 WILD-TYPE	193	186	188

'SGOL2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1639. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SGOL2 MUTATED	1	2	0
SGOL2 WILD-TYPE	203	217	147

'SGOL2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.714 (Fisher's exact test), Q value = 1

Table S1640. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SGOL2 MUTATED	3	3	1
SGOL2 WILD-TYPE	224	232	191

'SGOL2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.809 (Fisher's exact test), Q value = 1

Table S1641. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SGOL2 MUTATED	2	3	2
SGOL2 WILD-TYPE	194	187	266

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S1642. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SGOL2 MUTATED	1	1	1	1
SGOL2 WILD-TYPE	135	106	182	82

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1643. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SGOL2 MUTATED	2	1	1
SGOL2 WILD-TYPE	220	183	102

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.331 (Fisher's exact test), Q value = 1

Table S1644. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SGOL2 MUTATED	0	2	2
SGOL2 WILD-TYPE	184	160	157

'SGOL2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1645. Gene #152: 'SGOL2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SGOL2 MUTATED	1	1	2	0
SGOL2 WILD-TYPE	89	137	186	89

'GPR132 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.448 (Fisher's exact test), Q value = 1

Table S1646. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
GPR132 MUTATED	1	5	0
GPR132 WILD-TYPE	294	476	7

'GPR132 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S1647. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
GPR132 MUTATED	1	2	1	0
GPR132 WILD-TYPE	159	230	63	166

'GPR132 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.433 (Fisher's exact test), Q value = 1

Table S1648. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
GPR132 MUTATED	1	2	0
GPR132 WILD-TYPE	194	184	189

'GPR132 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1649. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
GPR132 MUTATED	1	1	1
GPR132 WILD-TYPE	203	218	146

'GPR132 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.744 (Fisher's exact test), Q value = 1

Table S1650. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
GPR132 MUTATED	2	1	2
GPR132 WILD-TYPE	225	234	190

'GPR132 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S1651. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
GPR132 MUTATED	1	2	2
GPR132 WILD-TYPE	195	188	266

'GPR132 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S1652. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GPR132 MUTATED	0	2	2	0
GPR132 WILD-TYPE	136	105	181	83

'GPR132 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.682 (Fisher's exact test), Q value = 1

Table S1653. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GPR132 MUTATED	1	2	1
GPR132 WILD-TYPE	221	182	102

'GPR132 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.332 (Fisher's exact test), Q value = 1

Table S1654. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GPR132 MUTATED	0	2	2
GPR132 WILD-TYPE	184	160	157

'GPR132 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.577 (Fisher's exact test), Q value = 1

Table S1655. Gene #153: 'GPR132 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GPR132 MUTATED	0	1	3	0
GPR132 WILD-TYPE	90	137	185	89

'TP63 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1656. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
TP63 MUTATED	1	1	2	1
TP63 WILD-TYPE	68	42	72	53

'TP63 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.733 (Fisher's exact test), Q value = 1

Table S1657. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
TP63 MUTATED	1	1	2	1
TP63 WILD-TYPE	62	49	46	78

'TP63 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.403 (Fisher's exact test), Q value = 1

Table S1658. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
TP63 MUTATED	1	1	1	3
TP63 WILD-TYPE	76	92	44	57

'TP63 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S1659. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
TP63 MUTATED	2	2	2
TP63 WILD-TYPE	136	59	74

'TP63 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.368 (Fisher's exact test), Q value = 1

Table S1660. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TP63 MUTATED	5	4	0
TP63 WILD-TYPE	290	477	7

'TP63 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0618 (Fisher's exact test), Q value = 0.47

Table S1661. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TP63 MUTATED	5	2	0	0
TP63 WILD-TYPE	155	230	64	166

'TP63 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0124 (Fisher's exact test), Q value = 0.19

Table S1662. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TP63 MUTATED	1	0	6
TP63 WILD-TYPE	194	186	183

Figure S263. Get High-res Image Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'TP63 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.273 (Fisher's exact test), Q value = 0.95

Table S1663. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TP63 MUTATED	4	3	0
TP63 WILD-TYPE	200	216	147

'TP63 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0426 (Fisher's exact test), Q value = 0.4

Table S1664. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TP63 MUTATED	5	1	0
TP63 WILD-TYPE	222	234	192

Figure S264. Get High-res Image Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'TP63 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0576 (Fisher's exact test), Q value = 0.45

Table S1665. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TP63 MUTATED	3	3	0
TP63 WILD-TYPE	193	187	268

'TP63 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.234 (Fisher's exact test), Q value = 0.9

Table S1666. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TP63 MUTATED	2	1	0	0
TP63 WILD-TYPE	134	106	183	83

'TP63 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S1667. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TP63 MUTATED	2	0	1
TP63 WILD-TYPE	220	184	102

'TP63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0637 (Fisher's exact test), Q value = 0.48

Table S1668. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TP63 MUTATED	0	3	0
TP63 WILD-TYPE	184	159	159

'TP63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.95

Table S1669. Gene #154: 'TP63 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TP63 MUTATED	1	2	0	0
TP63 WILD-TYPE	89	136	188	89

'ZNF334 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.328 (Fisher's exact test), Q value = 1

Table S1670. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
ZNF334 MUTATED	0	4	0
ZNF334 WILD-TYPE	295	477	7

'ZNF334 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S1671. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
ZNF334 MUTATED	1	1	0	2
ZNF334 WILD-TYPE	159	231	64	164

'ZNF334 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.778 (Fisher's exact test), Q value = 1

Table S1672. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
ZNF334 MUTATED	2	0	1
ZNF334 WILD-TYPE	193	186	188

'ZNF334 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.628 (Fisher's exact test), Q value = 1

Table S1673. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
ZNF334 MUTATED	2	1	0
ZNF334 WILD-TYPE	202	218	147

'ZNF334 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1674. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
ZNF334 MUTATED	1	2	1
ZNF334 WILD-TYPE	226	233	191

'ZNF334 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S1675. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
ZNF334 MUTATED	0	2	2
ZNF334 WILD-TYPE	196	188	266

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1676. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
ZNF334 MUTATED	1	1	2	0
ZNF334 WILD-TYPE	135	106	181	83

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.197 (Fisher's exact test), Q value = 0.85

Table S1677. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
ZNF334 MUTATED	2	0	2
ZNF334 WILD-TYPE	220	184	101

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S1678. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
ZNF334 MUTATED	1	2	1
ZNF334 WILD-TYPE	183	160	158

'ZNF334 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.578 (Fisher's exact test), Q value = 1

Table S1679. Gene #155: 'ZNF334 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
ZNF334 MUTATED	0	1	3	0
ZNF334 WILD-TYPE	90	137	185	89

'RGS3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.739 (Fisher's exact test), Q value = 1

Table S1680. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
RGS3 MUTATED	2	6	0
RGS3 WILD-TYPE	293	475	7

'RGS3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.253 (Fisher's exact test), Q value = 0.94

Table S1681. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
RGS3 MUTATED	3	4	0	0
RGS3 WILD-TYPE	157	228	64	166

'RGS3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.464 (Fisher's exact test), Q value = 1

Table S1682. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
RGS3 MUTATED	4	2	1
RGS3 WILD-TYPE	191	184	188

'RGS3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.185 (Fisher's exact test), Q value = 0.85

Table S1683. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
RGS3 MUTATED	5	1	1
RGS3 WILD-TYPE	199	218	146

'RGS3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.8 (Fisher's exact test), Q value = 1

Table S1684. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
RGS3 MUTATED	2	2	3
RGS3 WILD-TYPE	225	233	189

'RGS3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.501 (Fisher's exact test), Q value = 1

Table S1685. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
RGS3 MUTATED	1	3	3
RGS3 WILD-TYPE	195	187	265

'RGS3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.217 (Fisher's exact test), Q value = 0.88

Table S1686. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
RGS3 MUTATED	0	2	4	0
RGS3 WILD-TYPE	136	105	179	83

'RGS3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.756 (Fisher's exact test), Q value = 1

Table S1687. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
RGS3 MUTATED	2	2	2
RGS3 WILD-TYPE	220	182	101

'RGS3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.97

Table S1688. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
RGS3 MUTATED	1	1	4
RGS3 WILD-TYPE	183	161	155

'RGS3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.94 (Fisher's exact test), Q value = 1

Table S1689. Gene #156: 'RGS3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
RGS3 MUTATED	1	1	3	1
RGS3 WILD-TYPE	89	137	185	88

'NKX2-2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.136 (Fisher's exact test), Q value = 0.74

Table S1690. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
NKX2-2 MUTATED	0	6	0
NKX2-2 WILD-TYPE	295	475	7

'NKX2-2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.647 (Fisher's exact test), Q value = 1

Table S1691. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
NKX2-2 MUTATED	1	4	0	1
NKX2-2 WILD-TYPE	159	228	64	165

'NKX2-2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1692. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
NKX2-2 MUTATED	3	2	1
NKX2-2 WILD-TYPE	192	184	188

'NKX2-2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.885 (Fisher's exact test), Q value = 1

Table S1693. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
NKX2-2 MUTATED	2	3	1
NKX2-2 WILD-TYPE	202	216	146

'NKX2-2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.389 (Fisher's exact test), Q value = 1

Table S1694. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
NKX2-2 MUTATED	1	4	1
NKX2-2 WILD-TYPE	226	231	191

'NKX2-2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0187 (Fisher's exact test), Q value = 0.24

Table S1695. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
NKX2-2 MUTATED	0	5	1
NKX2-2 WILD-TYPE	196	185	267

Figure S265. Get High-res Image Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.802 (Fisher's exact test), Q value = 1

Table S1696. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
NKX2-2 MUTATED	2	2	2	0
NKX2-2 WILD-TYPE	134	105	181	83

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1697. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
NKX2-2 MUTATED	3	2	1
NKX2-2 WILD-TYPE	219	182	102

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0692 (Fisher's exact test), Q value = 0.5

Table S1698. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
NKX2-2 MUTATED	0	2	4
NKX2-2 WILD-TYPE	184	160	155

'NKX2-2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.888 (Fisher's exact test), Q value = 1

Table S1699. Gene #157: 'NKX2-2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
NKX2-2 MUTATED	1	2	3	0
NKX2-2 WILD-TYPE	89	136	185	89

'SEZ6L2 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1700. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
SEZ6L2 MUTATED	2	0	1	1
SEZ6L2 WILD-TYPE	67	43	73	53

'SEZ6L2 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.472 (Fisher's exact test), Q value = 1

Table S1701. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
SEZ6L2 MUTATED	1	0	0	3
SEZ6L2 WILD-TYPE	62	50	48	76

'SEZ6L2 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.101 (Fisher's exact test), Q value = 0.63

Table S1702. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
SEZ6L2 MUTATED	3	0	1	0
SEZ6L2 WILD-TYPE	74	93	44	60

'SEZ6L2 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.124 (Fisher's exact test), Q value = 0.69

Table S1703. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
SEZ6L2 MUTATED	1	0	3
SEZ6L2 WILD-TYPE	137	61	73

'SEZ6L2 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.473 (Fisher's exact test), Q value = 1

Table S1704. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SEZ6L2 MUTATED	4	3	0
SEZ6L2 WILD-TYPE	291	478	7

'SEZ6L2 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S1705. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SEZ6L2 MUTATED	1	1	0	2
SEZ6L2 WILD-TYPE	159	231	64	164

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.0113 (Fisher's exact test), Q value = 0.18

Table S1706. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SEZ6L2 MUTATED	0	4	0
SEZ6L2 WILD-TYPE	195	182	189

Figure S266. Get High-res Image Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

'SEZ6L2 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0041 (Fisher's exact test), Q value = 0.083

Table S1707. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SEZ6L2 MUTATED	0	0	4
SEZ6L2 WILD-TYPE	204	219	143

Figure S267. Get High-res Image Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.168 (Fisher's exact test), Q value = 0.81

Table S1708. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SEZ6L2 MUTATED	2	0	3
SEZ6L2 WILD-TYPE	225	235	189

'SEZ6L2 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1709. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SEZ6L2 MUTATED	2	1	2
SEZ6L2 WILD-TYPE	194	189	266

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.28 (Fisher's exact test), Q value = 0.95

Table S1710. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SEZ6L2 MUTATED	0	0	3	0
SEZ6L2 WILD-TYPE	136	107	180	83

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0984 (Fisher's exact test), Q value = 0.62

Table S1711. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SEZ6L2 MUTATED	0	3	0
SEZ6L2 WILD-TYPE	222	181	103

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.0303 (Fisher's exact test), Q value = 0.31

Table S1712. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SEZ6L2 MUTATED	0	0	3
SEZ6L2 WILD-TYPE	184	162	156

Figure S268. Get High-res Image Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

'SEZ6L2 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.317 (Fisher's exact test), Q value = 0.99

Table S1713. Gene #158: 'SEZ6L2 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SEZ6L2 MUTATED	0	0	3	0
SEZ6L2 WILD-TYPE	90	138	185	89

'MYH8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.869 (Fisher's exact test), Q value = 1

Table S1714. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
MYH8 MUTATED	2	0	2	1
MYH8 WILD-TYPE	67	43	72	53

'MYH8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.729 (Fisher's exact test), Q value = 1

Table S1715. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
MYH8 MUTATED	1	1	2	1
MYH8 WILD-TYPE	62	49	46	78

'MYH8 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.306 (Fisher's exact test), Q value = 0.98

Table S1716. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
MYH8 MUTATED	3	1	0	3
MYH8 WILD-TYPE	74	92	45	57

'MYH8 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.0846 (Fisher's exact test), Q value = 0.57

Table S1717. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
MYH8 MUTATED	1	3	3
MYH8 WILD-TYPE	137	58	73

'MYH8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.48 (Fisher's exact test), Q value = 1

Table S1718. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
MYH8 MUTATED	10	11	0
MYH8 WILD-TYPE	285	470	7

'MYH8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.2 (Fisher's exact test), Q value = 0.85

Table S1719. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
MYH8 MUTATED	8	7	0	3
MYH8 WILD-TYPE	152	225	64	163

'MYH8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.303 (Fisher's exact test), Q value = 0.98

Table S1720. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
MYH8 MUTATED	7	2	5
MYH8 WILD-TYPE	188	184	184

'MYH8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.228 (Fisher's exact test), Q value = 0.89

Table S1721. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
MYH8 MUTATED	7	6	1
MYH8 WILD-TYPE	197	213	146

'MYH8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.265 (Fisher's exact test), Q value = 0.95

Table S1722. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
MYH8 MUTATED	8	3	6
MYH8 WILD-TYPE	219	232	186

'MYH8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.429 (Fisher's exact test), Q value = 1

Table S1723. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
MYH8 MUTATED	5	7	5
MYH8 WILD-TYPE	191	183	263

'MYH8 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.854 (Fisher's exact test), Q value = 1

Table S1724. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
MYH8 MUTATED	4	4	4	2
MYH8 WILD-TYPE	132	103	179	81

'MYH8 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.252 (Fisher's exact test), Q value = 0.94

Table S1725. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
MYH8 MUTATED	6	3	5
MYH8 WILD-TYPE	216	181	98

'MYH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.838 (Fisher's exact test), Q value = 1

Table S1726. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
MYH8 MUTATED	4	5	5
MYH8 WILD-TYPE	180	157	154

'MYH8 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S1727. Gene #159: 'MYH8 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
MYH8 MUTATED	2	3	5	4
MYH8 WILD-TYPE	88	135	183	85

'CYP11A1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.784 (Fisher's exact test), Q value = 1

Table S1728. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
CYP11A1 MUTATED	1	0	2	0
CYP11A1 WILD-TYPE	68	43	72	54

'CYP11A1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.893 (Fisher's exact test), Q value = 1

Table S1729. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CYP11A1 MUTATED	1	0	1	1
CYP11A1 WILD-TYPE	62	50	47	78

'CYP11A1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.874 (Fisher's exact test), Q value = 1

Table S1730. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
CYP11A1 MUTATED	1	2	0	0
CYP11A1 WILD-TYPE	76	91	45	60

'CYP11A1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.312 (Fisher's exact test), Q value = 0.98

Table S1731. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CYP11A1 MUTATED	1	0	2
CYP11A1 WILD-TYPE	137	61	74

'CYP11A1 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1732. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CYP11A1 MUTATED	3	4	0
CYP11A1 WILD-TYPE	292	477	7

'CYP11A1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.665 (Fisher's exact test), Q value = 1

Table S1733. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CYP11A1 MUTATED	1	1	1	2
CYP11A1 WILD-TYPE	159	231	63	164

'CYP11A1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1734. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CYP11A1 MUTATED	2	1	2
CYP11A1 WILD-TYPE	193	185	187

'CYP11A1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.449 (Fisher's exact test), Q value = 1

Table S1735. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CYP11A1 MUTATED	2	3	0
CYP11A1 WILD-TYPE	202	216	147

'CYP11A1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0414 (Fisher's exact test), Q value = 0.39

Table S1736. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CYP11A1 MUTATED	5	0	2
CYP11A1 WILD-TYPE	222	235	190

Figure S269. Get High-res Image Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'CYP11A1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.392 (Fisher's exact test), Q value = 1

Table S1737. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CYP11A1 MUTATED	4	1	2
CYP11A1 WILD-TYPE	192	189	266

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.913 (Fisher's exact test), Q value = 1

Table S1738. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CYP11A1 MUTATED	1	1	1	1
CYP11A1 WILD-TYPE	135	106	182	82

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.681 (Fisher's exact test), Q value = 1

Table S1739. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CYP11A1 MUTATED	1	2	1
CYP11A1 WILD-TYPE	221	182	102

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.839 (Fisher's exact test), Q value = 1

Table S1740. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CYP11A1 MUTATED	1	2	1
CYP11A1 WILD-TYPE	183	160	158

'CYP11A1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.237 (Fisher's exact test), Q value = 0.91

Table S1741. Gene #160: 'CYP11A1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CYP11A1 MUTATED	0	0	2	2
CYP11A1 WILD-TYPE	90	138	186	87

'TJAP1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.573 (Fisher's exact test), Q value = 1

Table S1742. Gene #161: 'TJAP1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TJAP1 MUTATED	2	1	0
TJAP1 WILD-TYPE	293	480	7

'TJAP1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0462 (Fisher's exact test), Q value = 0.41

Table S1743. Gene #161: 'TJAP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TJAP1 MUTATED	3	0	0	0
TJAP1 WILD-TYPE	157	232	64	166

Figure S270. Get High-res Image Gene #161: 'TJAP1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'PRKCD MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.17 (Fisher's exact test), Q value = 0.81

Table S1744. Gene #162: 'PRKCD MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PRKCD MUTATED	0	2	1	0
PRKCD WILD-TYPE	69	41	73	54

'PRKCD MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.0822 (Fisher's exact test), Q value = 0.56

Table S1745. Gene #162: 'PRKCD MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PRKCD MUTATED	0	2	1	0
PRKCD WILD-TYPE	63	48	47	79

'PRKCD MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.164 (Fisher's exact test), Q value = 0.81

Table S1746. Gene #162: 'PRKCD MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PRKCD MUTATED	0	3	0	0
PRKCD WILD-TYPE	77	90	45	60

'PRKCD MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1747. Gene #162: 'PRKCD MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PRKCD MUTATED	2	0	1
PRKCD WILD-TYPE	136	61	75

'PRKCD MUTATION STATUS' versus 'CN_CNMF'

P value = 0.00418 (Fisher's exact test), Q value = 0.083

Table S1748. Gene #162: 'PRKCD MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PRKCD MUTATED	2	0	1
PRKCD WILD-TYPE	293	481	6

Figure S271. Get High-res Image Gene #162: 'PRKCD MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FLNB MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.413 (Fisher's exact test), Q value = 1

Table S1749. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
FLNB MUTATED	2	0	0	1
FLNB WILD-TYPE	67	43	74	53

'FLNB MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.347 (Fisher's exact test), Q value = 1

Table S1750. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
FLNB MUTATED	2	1	0	0
FLNB WILD-TYPE	61	49	48	79

'FLNB MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.201 (Fisher's exact test), Q value = 0.85

Table S1751. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
FLNB MUTATED	2	0	1	0
FLNB WILD-TYPE	75	93	44	60

'FLNB MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.604 (Fisher's exact test), Q value = 1

Table S1752. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
FLNB MUTATED	2	1	0
FLNB WILD-TYPE	136	60	76

'FLNB MUTATION STATUS' versus 'CN_CNMF'

P value = 0.0256 (Fisher's exact test), Q value = 0.28

Table S1753. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
FLNB MUTATED	1	7	1
FLNB WILD-TYPE	294	474	6

Figure S272. Get High-res Image Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

'FLNB MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.906 (Fisher's exact test), Q value = 1

Table S1754. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
FLNB MUTATED	1	3	1	2
FLNB WILD-TYPE	159	229	63	164

'FLNB MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.803 (Fisher's exact test), Q value = 1

Table S1755. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
FLNB MUTATED	2	3	2
FLNB WILD-TYPE	193	183	187

'FLNB MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S1756. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
FLNB MUTATED	2	4	1
FLNB WILD-TYPE	202	215	146

'FLNB MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1757. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
FLNB MUTATED	4	3	2
FLNB WILD-TYPE	223	232	190

'FLNB MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.407 (Fisher's exact test), Q value = 1

Table S1758. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
FLNB MUTATED	3	4	2
FLNB WILD-TYPE	193	186	266

'FLNB MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.465 (Fisher's exact test), Q value = 1

Table S1759. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
FLNB MUTATED	2	3	2	0
FLNB WILD-TYPE	134	104	181	83

'FLNB MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1760. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
FLNB MUTATED	3	2	2
FLNB WILD-TYPE	219	182	101

'FLNB MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1761. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
FLNB MUTATED	3	1	3
FLNB WILD-TYPE	181	161	156

'FLNB MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.708 (Fisher's exact test), Q value = 1

Table S1762. Gene #163: 'FLNB MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
FLNB MUTATED	0	2	4	1
FLNB WILD-TYPE	90	136	184	88

'PAN3 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.567 (Fisher's exact test), Q value = 1

Table S1763. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
PAN3 MUTATED	3	0	1	1
PAN3 WILD-TYPE	66	43	73	53

'PAN3 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.3 (Fisher's exact test), Q value = 0.98

Table S1764. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
PAN3 MUTATED	2	2	1	0
PAN3 WILD-TYPE	61	48	47	79

'PAN3 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.598 (Fisher's exact test), Q value = 1

Table S1765. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
PAN3 MUTATED	2	3	1	0
PAN3 WILD-TYPE	75	90	44	60

'PAN3 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.648 (Fisher's exact test), Q value = 1

Table S1766. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
PAN3 MUTATED	2	2	2
PAN3 WILD-TYPE	136	59	74

'PAN3 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.471 (Fisher's exact test), Q value = 1

Table S1767. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
PAN3 MUTATED	4	3	0
PAN3 WILD-TYPE	291	478	7

'PAN3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1768. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
PAN3 MUTATED	1	1	1
PAN3 WILD-TYPE	194	185	188

'PAN3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.363 (Fisher's exact test), Q value = 1

Table S1769. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
PAN3 MUTATED	2	0	1
PAN3 WILD-TYPE	202	219	146

'PAN3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.401 (Fisher's exact test), Q value = 1

Table S1770. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
PAN3 MUTATED	2	0	1
PAN3 WILD-TYPE	225	235	191

'PAN3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.489 (Fisher's exact test), Q value = 1

Table S1771. Gene #164: 'PAN3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
PAN3 MUTATED	2	0	1
PAN3 WILD-TYPE	194	190	267

'CHD8 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.699 (Fisher's exact test), Q value = 1

Table S1772. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
CHD8 MUTATED	3	2	1	2
CHD8 WILD-TYPE	66	41	73	52

'CHD8 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.532 (Fisher's exact test), Q value = 1

Table S1773. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
CHD8 MUTATED	2	2	0	4
CHD8 WILD-TYPE	61	48	48	75

'CHD8 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.135 (Fisher's exact test), Q value = 0.73

Table S1774. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
CHD8 MUTATED	0	3	3	2
CHD8 WILD-TYPE	77	90	42	58

'CHD8 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.646 (Fisher's exact test), Q value = 1

Table S1775. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
CHD8 MUTATED	5	2	1
CHD8 WILD-TYPE	133	59	75

'CHD8 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.199 (Fisher's exact test), Q value = 0.85

Table S1776. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CHD8 MUTATED	7	4	0
CHD8 WILD-TYPE	288	477	7

'CHD8 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0504 (Fisher's exact test), Q value = 0.43

Table S1777. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CHD8 MUTATED	5	1	2	1
CHD8 WILD-TYPE	155	231	62	165

'CHD8 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.293 (Fisher's exact test), Q value = 0.97

Table S1778. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CHD8 MUTATED	5	4	1
CHD8 WILD-TYPE	190	182	188

'CHD8 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.479 (Fisher's exact test), Q value = 1

Table S1779. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CHD8 MUTATED	2	4	4
CHD8 WILD-TYPE	202	215	143

'CHD8 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0169 (Fisher's exact test), Q value = 0.22

Table S1780. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CHD8 MUTATED	6	0	2
CHD8 WILD-TYPE	221	235	190

Figure S273. Get High-res Image Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'CHD8 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0186 (Fisher's exact test), Q value = 0.24

Table S1781. Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CHD8 MUTATED	6	0	2
CHD8 WILD-TYPE	190	190	266

Figure S274. Get High-res Image Gene #165: 'CHD8 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'TTYH3 MUTATION STATUS' versus 'CN_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1782. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
TTYH3 MUTATED	1	3	0
TTYH3 WILD-TYPE	294	478	7

'TTYH3 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.721 (Fisher's exact test), Q value = 1

Table S1783. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
TTYH3 MUTATED	1	1	1	1
TTYH3 WILD-TYPE	159	231	63	165

'TTYH3 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.774 (Fisher's exact test), Q value = 1

Table S1784. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
TTYH3 MUTATED	2	0	1
TTYH3 WILD-TYPE	193	186	188

'TTYH3 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.787 (Fisher's exact test), Q value = 1

Table S1785. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
TTYH3 MUTATED	1	2	0
TTYH3 WILD-TYPE	203	217	147

'TTYH3 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.515 (Fisher's exact test), Q value = 1

Table S1786. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
TTYH3 MUTATED	0	2	1
TTYH3 WILD-TYPE	227	233	191

'TTYH3 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.633 (Fisher's exact test), Q value = 1

Table S1787. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
TTYH3 MUTATED	0	1	2
TTYH3 WILD-TYPE	196	189	266

'TTYH3 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.773 (Fisher's exact test), Q value = 1

Table S1788. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
TTYH3 MUTATED	1	0	1	1
TTYH3 WILD-TYPE	135	107	182	82

'TTYH3 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1789. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
TTYH3 MUTATED	2	1	0
TTYH3 WILD-TYPE	220	183	103

'TTYH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S1790. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
TTYH3 MUTATED	2	0	1
TTYH3 WILD-TYPE	182	162	158

'TTYH3 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1791. Gene #166: 'TTYH3 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
TTYH3 MUTATED	0	1	2	0
TTYH3 WILD-TYPE	90	137	186	89

'SLFN11 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.668 (Fisher's exact test), Q value = 1

Table S1792. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
SLFN11 MUTATED	1	4	0
SLFN11 WILD-TYPE	294	477	7

'SLFN11 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1793. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
SLFN11 MUTATED	1	2	0	1
SLFN11 WILD-TYPE	159	230	64	165

'SLFN11 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.292 (Fisher's exact test), Q value = 0.97

Table S1794. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
SLFN11 MUTATED	3	2	0
SLFN11 WILD-TYPE	192	184	189

'SLFN11 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.641 (Fisher's exact test), Q value = 1

Table S1795. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
SLFN11 MUTATED	2	1	2
SLFN11 WILD-TYPE	202	218	145

'SLFN11 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S1796. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
SLFN11 MUTATED	1	1	2
SLFN11 WILD-TYPE	226	234	190

'SLFN11 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.481 (Fisher's exact test), Q value = 1

Table S1797. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
SLFN11 MUTATED	0	2	2
SLFN11 WILD-TYPE	196	188	266

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.59 (Fisher's exact test), Q value = 1

Table S1798. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
SLFN11 MUTATED	1	2	1	0
SLFN11 WILD-TYPE	135	105	182	83

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.263 (Fisher's exact test), Q value = 0.95

Table S1799. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
SLFN11 MUTATED	3	0	1
SLFN11 WILD-TYPE	219	184	102

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.475 (Fisher's exact test), Q value = 1

Table S1800. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
SLFN11 MUTATED	2	0	2
SLFN11 WILD-TYPE	182	162	157

'SLFN11 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.761 (Fisher's exact test), Q value = 1

Table S1801. Gene #167: 'SLFN11 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
SLFN11 MUTATED	0	2	2	0
SLFN11 WILD-TYPE	90	136	186	89

'CIB1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.667 (Fisher's exact test), Q value = 1

Table S1802. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
CIB1 MUTATED	1	4	0
CIB1 WILD-TYPE	294	477	7

'CIB1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1803. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
CIB1 MUTATED	1	2	0	2
CIB1 WILD-TYPE	159	230	64	164

'CIB1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1804. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
CIB1 MUTATED	2	1	2
CIB1 WILD-TYPE	193	185	187

'CIB1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.0506 (Fisher's exact test), Q value = 0.43

Table S1805. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
CIB1 MUTATED	4	0	1
CIB1 WILD-TYPE	200	219	146

'CIB1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.687 (Fisher's exact test), Q value = 1

Table S1806. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
CIB1 MUTATED	1	1	2
CIB1 WILD-TYPE	226	234	190

'CIB1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.314 (Fisher's exact test), Q value = 0.98

Table S1807. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
CIB1 MUTATED	0	1	3
CIB1 WILD-TYPE	196	189	265

'CIB1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.216 (Fisher's exact test), Q value = 0.87

Table S1808. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
CIB1 MUTATED	0	1	1	2
CIB1 WILD-TYPE	136	106	182	81

'CIB1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0433 (Fisher's exact test), Q value = 0.4

Table S1809. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
CIB1 MUTATED	0	4	0
CIB1 WILD-TYPE	222	180	103

Figure S275. Get High-res Image Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'CIB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.117 (Fisher's exact test), Q value = 0.67

Table S1810. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
CIB1 MUTATED	0	3	1
CIB1 WILD-TYPE	184	159	158

'CIB1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.32 (Fisher's exact test), Q value = 0.99

Table S1811. Gene #168: 'CIB1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
CIB1 MUTATED	0	3	1	0
CIB1 WILD-TYPE	90	135	187	89

'GLYAT MUTATION STATUS' versus 'CN_CNMF'

P value = 0.672 (Fisher's exact test), Q value = 1

Table S1812. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
GLYAT MUTATED	1	4	0
GLYAT WILD-TYPE	294	477	7

'GLYAT MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.922 (Fisher's exact test), Q value = 1

Table S1813. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
GLYAT MUTATED	2	2	0	1
GLYAT WILD-TYPE	158	230	64	165

'GLYAT MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.553 (Fisher's exact test), Q value = 1

Table S1814. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
GLYAT MUTATED	2	0	2
GLYAT WILD-TYPE	193	186	187

'GLYAT MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.679 (Fisher's exact test), Q value = 1

Table S1815. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
GLYAT MUTATED	2	2	0
GLYAT WILD-TYPE	202	217	147

'GLYAT MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.388 (Fisher's exact test), Q value = 1

Table S1816. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
GLYAT MUTATED	2	3	0
GLYAT WILD-TYPE	225	232	192

'GLYAT MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.4 (Fisher's exact test), Q value = 1

Table S1817. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
GLYAT MUTATED	1	3	1
GLYAT WILD-TYPE	195	187	267

'GLYAT MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.194 (Fisher's exact test), Q value = 0.85

Table S1818. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
GLYAT MUTATED	1	2	0	1
GLYAT WILD-TYPE	135	105	183	82

'GLYAT MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.265 (Fisher's exact test), Q value = 0.95

Table S1819. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
GLYAT MUTATED	3	0	1
GLYAT WILD-TYPE	219	184	102

'GLYAT MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.837 (Fisher's exact test), Q value = 1

Table S1820. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
GLYAT MUTATED	1	2	1
GLYAT WILD-TYPE	183	160	158

'GLYAT MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.698 (Fisher's exact test), Q value = 1

Table S1821. Gene #169: 'GLYAT MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
GLYAT MUTATED	1	2	1	0
GLYAT WILD-TYPE	89	136	187	89

'IGFN1 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1822. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
IGFN1 MUTATED	1	1	1	1
IGFN1 WILD-TYPE	68	42	73	53

'IGFN1 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1823. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
IGFN1 MUTATED	1	1	1	1
IGFN1 WILD-TYPE	62	49	47	78

'IGFN1 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.772 (Fisher's exact test), Q value = 1

Table S1824. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
IGFN1 MUTATED	2	1	1	2
IGFN1 WILD-TYPE	75	92	44	58

'IGFN1 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.558 (Fisher's exact test), Q value = 1

Table S1825. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
IGFN1 MUTATED	4	0	2
IGFN1 WILD-TYPE	134	61	74

'IGFN1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.124 (Fisher's exact test), Q value = 0.69

Table S1826. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
IGFN1 MUTATED	6	2	0
IGFN1 WILD-TYPE	289	479	7

'IGFN1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.00086 (Fisher's exact test), Q value = 0.023

Table S1827. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
IGFN1 MUTATED	6	0	0	0
IGFN1 WILD-TYPE	154	232	64	166

Figure S276. Get High-res Image Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'IGFN1 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.871 (Fisher's exact test), Q value = 1

Table S1828. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
IGFN1 MUTATED	2	2	1
IGFN1 WILD-TYPE	193	184	188

'IGFN1 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.644 (Fisher's exact test), Q value = 1

Table S1829. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
IGFN1 MUTATED	2	1	2
IGFN1 WILD-TYPE	202	218	145

'IGFN1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0224 (Fisher's exact test), Q value = 0.26

Table S1830. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
IGFN1 MUTATED	5	0	1
IGFN1 WILD-TYPE	222	235	191

Figure S277. Get High-res Image Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'IGFN1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.19 (Fisher's exact test), Q value = 0.85

Table S1831. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
IGFN1 MUTATED	4	1	1
IGFN1 WILD-TYPE	192	189	267

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1832. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
IGFN1 MUTATED	1	1	1	0
IGFN1 WILD-TYPE	135	106	182	83

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.00813 (Fisher's exact test), Q value = 0.14

Table S1833. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
IGFN1 MUTATED	0	0	3
IGFN1 WILD-TYPE	222	184	100

Figure S278. Get High-res Image Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.412 (Fisher's exact test), Q value = 1

Table S1834. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
IGFN1 MUTATED	1	0	2
IGFN1 WILD-TYPE	183	162	157

'IGFN1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.149 (Fisher's exact test), Q value = 0.77

Table S1835. Gene #170: 'IGFN1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
IGFN1 MUTATED	0	0	1	2
IGFN1 WILD-TYPE	90	138	187	87

'LRRC55 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.375 (Fisher's exact test), Q value = 1

Table S1836. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
LRRC55 MUTATED	0	1	3	1
LRRC55 WILD-TYPE	69	42	71	53

'LRRC55 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.537 (Fisher's exact test), Q value = 1

Table S1837. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
LRRC55 MUTATED	0	1	1	3
LRRC55 WILD-TYPE	63	49	47	76

'LRRC55 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.334 (Fisher's exact test), Q value = 1

Table S1838. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
LRRC55 MUTATED	3	3	0	0
LRRC55 WILD-TYPE	74	90	45	60

'LRRC55 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.868 (Fisher's exact test), Q value = 1

Table S1839. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
LRRC55 MUTATED	4	1	1
LRRC55 WILD-TYPE	134	60	75

'LRRC55 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.161 (Fisher's exact test), Q value = 0.8

Table S1840. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
LRRC55 MUTATED	6	3	0
LRRC55 WILD-TYPE	289	478	7

'LRRC55 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.249 (Fisher's exact test), Q value = 0.93

Table S1841. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
LRRC55 MUTATED	3	2	0	0
LRRC55 WILD-TYPE	157	230	64	166

'LRRC55 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1842. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
LRRC55 MUTATED	2	1	2
LRRC55 WILD-TYPE	193	185	187

'LRRC55 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.542 (Fisher's exact test), Q value = 1

Table S1843. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
LRRC55 MUTATED	3	1	1
LRRC55 WILD-TYPE	201	218	146

'LRRC55 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.842 (Fisher's exact test), Q value = 1

Table S1844. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
LRRC55 MUTATED	2	1	1
LRRC55 WILD-TYPE	225	234	191

'LRRC55 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.696 (Fisher's exact test), Q value = 1

Table S1845. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
LRRC55 MUTATED	1	2	1
LRRC55 WILD-TYPE	195	188	267

'LRRC55 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.0135 (Fisher's exact test), Q value = 0.19

Table S1846. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
LRRC55 MUTATED	0	3	0	0
LRRC55 WILD-TYPE	136	104	183	83

Figure S279. Get High-res Image Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

'LRRC55 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.794 (Fisher's exact test), Q value = 1

Table S1847. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
LRRC55 MUTATED	1	1	1
LRRC55 WILD-TYPE	221	183	102

'LRRC55 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.208 (Fisher's exact test), Q value = 0.86

Table S1848. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
LRRC55 MUTATED	0	1	2
LRRC55 WILD-TYPE	184	161	157

'LRRC55 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 1 (Fisher's exact test), Q value = 1

Table S1849. Gene #171: 'LRRC55 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
LRRC55 MUTATED	0	1	2	0
LRRC55 WILD-TYPE	90	137	186	89

'WDR63 MUTATION STATUS' versus 'MRNA_CNMF'

P value = 0.0956 (Fisher's exact test), Q value = 0.6

Table S1850. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #1: 'MRNA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	69	43	74	54
WDR63 MUTATED	2	2	0	0
WDR63 WILD-TYPE	67	41	74	54

'WDR63 MUTATION STATUS' versus 'MRNA_CHIERARCHICAL'

P value = 0.601 (Fisher's exact test), Q value = 1

Table S1851. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #2: 'MRNA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	63	50	48	79
WDR63 MUTATED	1	2	0	1
WDR63 WILD-TYPE	62	48	48	78

'WDR63 MUTATION STATUS' versus 'MIR_CNMF'

P value = 0.675 (Fisher's exact test), Q value = 1

Table S1852. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #3: 'MIR_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	77	93	45	60
WDR63 MUTATED	2	2	1	0
WDR63 WILD-TYPE	75	91	44	60

'WDR63 MUTATION STATUS' versus 'MIR_CHIERARCHICAL'

P value = 0.139 (Fisher's exact test), Q value = 0.74

Table S1853. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #4: 'MIR_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	138	61	76
WDR63 MUTATED	5	0	0
WDR63 WILD-TYPE	133	61	76

'WDR63 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.165 (Fisher's exact test), Q value = 0.81

Table S1854. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
WDR63 MUTATED	6	3	0
WDR63 WILD-TYPE	289	478	7

'WDR63 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.071 (Fisher's exact test), Q value = 0.51

Table S1855. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
WDR63 MUTATED	4	1	0	0
WDR63 WILD-TYPE	156	231	64	166

'WDR63 MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.876 (Fisher's exact test), Q value = 1

Table S1856. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
WDR63 MUTATED	3	1	2
WDR63 WILD-TYPE	192	185	187

'WDR63 MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.299 (Fisher's exact test), Q value = 0.97

Table S1857. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
WDR63 MUTATED	4	1	1
WDR63 WILD-TYPE	200	218	146

'WDR63 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.0119 (Fisher's exact test), Q value = 0.18

Table S1858. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
WDR63 MUTATED	6	1	0
WDR63 WILD-TYPE	221	234	192

Figure S280. Get High-res Image Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

'WDR63 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.0301 (Fisher's exact test), Q value = 0.31

Table S1859. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
WDR63 MUTATED	4	3	0
WDR63 WILD-TYPE	192	187	268

Figure S281. Get High-res Image Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

'WDR63 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 0.912 (Fisher's exact test), Q value = 1

Table S1860. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
WDR63 MUTATED	1	1	1	1
WDR63 WILD-TYPE	135	106	182	82

'WDR63 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0268 (Fisher's exact test), Q value = 0.29

Table S1861. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
WDR63 MUTATED	1	0	3
WDR63 WILD-TYPE	221	184	100

Figure S282. Get High-res Image Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'WDR63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1862. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
WDR63 MUTATED	2	1	1
WDR63 WILD-TYPE	182	161	158

'WDR63 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.432 (Fisher's exact test), Q value = 1

Table S1863. Gene #172: 'WDR63 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
WDR63 MUTATED	0	1	1	2
WDR63 WILD-TYPE	90	137	187	87

'KIF26B MUTATION STATUS' versus 'CN_CNMF'

P value = 0.695 (Fisher's exact test), Q value = 1

Table S1864. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
KIF26B MUTATED	3	3	0
KIF26B WILD-TYPE	292	478	7

'KIF26B MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.0133 (Fisher's exact test), Q value = 0.19

Table S1865. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
KIF26B MUTATED	5	0	0	1
KIF26B WILD-TYPE	155	232	64	165

Figure S283. Get High-res Image Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

'KIF26B MUTATION STATUS' versus 'RPPA_CNMF'

P value = 0.872 (Fisher's exact test), Q value = 1

Table S1866. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #7: 'RPPA_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	195	186	189
KIF26B MUTATED	2	2	1
KIF26B WILD-TYPE	193	184	188

'KIF26B MUTATION STATUS' versus 'RPPA_CHIERARCHICAL'

P value = 0.543 (Fisher's exact test), Q value = 1

Table S1867. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #8: 'RPPA_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	204	219	147
KIF26B MUTATED	3	1	1
KIF26B WILD-TYPE	201	218	146

'KIF26B MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.123 (Fisher's exact test), Q value = 0.69

Table S1868. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
KIF26B MUTATED	3	0	3
KIF26B WILD-TYPE	224	235	189

'KIF26B MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.884 (Fisher's exact test), Q value = 1

Table S1869. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
KIF26B MUTATED	2	1	3
KIF26B WILD-TYPE	194	189	265

'KIF26B MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1870. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
KIF26B MUTATED	1	1	2	1
KIF26B WILD-TYPE	135	106	181	82

'KIF26B MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.0034 (Fisher's exact test), Q value = 0.072

Table S1871. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
KIF26B MUTATED	0	1	4
KIF26B WILD-TYPE	222	183	99

Figure S284. Get High-res Image Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

'KIF26B MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.456 (Fisher's exact test), Q value = 1

Table S1872. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
KIF26B MUTATED	1	1	3
KIF26B WILD-TYPE	183	161	156

'KIF26B MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.0847 (Fisher's exact test), Q value = 0.57

Table S1873. Gene #173: 'KIF26B MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
KIF26B MUTATED	0	0	2	3
KIF26B WILD-TYPE	90	138	186	86

'AGXT2L1 MUTATION STATUS' versus 'CN_CNMF'

P value = 0.651 (Fisher's exact test), Q value = 1

Table S1874. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #5: 'CN_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	295	481	7
AGXT2L1 MUTATED	2	2	0
AGXT2L1 WILD-TYPE	293	479	7

'AGXT2L1 MUTATION STATUS' versus 'METHLYATION_CNMF'

P value = 0.296 (Fisher's exact test), Q value = 0.97

Table S1875. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #6: 'METHLYATION_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	160	232	64	166
AGXT2L1 MUTATED	2	0	0	1
AGXT2L1 WILD-TYPE	158	232	64	165

'AGXT2L1 MUTATION STATUS' versus 'MRNASEQ_CNMF'

P value = 0.157 (Fisher's exact test), Q value = 0.79

Table S1876. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #9: 'MRNASEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	227	235	192
AGXT2L1 MUTATED	3	0	1
AGXT2L1 WILD-TYPE	224	235	191

'AGXT2L1 MUTATION STATUS' versus 'MRNASEQ_CHIERARCHICAL'

P value = 0.822 (Fisher's exact test), Q value = 1

Table S1877. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #10: 'MRNASEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	196	190	268
AGXT2L1 MUTATED	2	1	1
AGXT2L1 WILD-TYPE	194	189	267

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_CNMF'

P value = 1 (Fisher's exact test), Q value = 1

Table S1878. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #11: 'MIRSEQ_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	136	107	183	83
AGXT2L1 MUTATED	1	1	1	0
AGXT2L1 WILD-TYPE	135	106	182	83

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_CHIERARCHICAL'

P value = 0.793 (Fisher's exact test), Q value = 1

Table S1879. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #12: 'MIRSEQ_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	222	184	103
AGXT2L1 MUTATED	1	1	1
AGXT2L1 WILD-TYPE	221	183	102

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CNMF'

P value = 0.41 (Fisher's exact test), Q value = 1

Table S1880. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #13: 'MIRSEQ_MATURE_CNMF'

nPatients	CLUS_1	CLUS_2	CLUS_3
ALL	184	162	159
AGXT2L1 MUTATED	1	0	2
AGXT2L1 WILD-TYPE	183	162	157

'AGXT2L1 MUTATION STATUS' versus 'MIRSEQ_MATURE_CHIERARCHICAL'

P value = 0.586 (Fisher's exact test), Q value = 1

Table S1881. Gene #174: 'AGXT2L1 MUTATION STATUS' versus Molecular Subtype #14: 'MIRSEQ_MATURE_CHIERARCHICAL'

nPatients	CLUS_1	CLUS_2	CLUS_3	CLUS_4
ALL	90	138	188	89
AGXT2L1 MUTATED	1	0	2	0
AGXT2L1 WILD-TYPE	89	138	186	89

Methods & Data

Input

Mutation data file = sample_sig_gene_table.txt from Mutsig_2CV pipeline
Processed Mutation data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/GBMLGG-TP/20223848/transformed.cor.cli.txt
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/GBMLGG-TP/20148947/GBMLGG-TP.transferedmergedcluster.txt
Number of patients = 796
Number of significantly mutated genes = 174
Number of Molecular subtypes = 14
Exclude genes that fewer than K tumors have mutations, K = 3

Fisher's exact test

For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R

Q value calculation

For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.

References

[1] Fisher, R.A., On the interpretation of chi-square from contingency tables, and the calculation of P, Journal of the Royal Statistical Society 85(1):87-94 (1922)

[2] Benjamini and Hochberg, Controlling the false discovery rate: a practical and powerful approach to multiple testing, Journal of the Royal Statistical Society Series B 59:289-300 (1995)

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