		Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nCNV (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
1p gain	12 (7%)	153	0.51267	0.877	0.93998	1	0.82644	1	0.52798	0.885	0.24994	0.697	0.26251	0.712	0.33411	0.787	0.59388	0.908	0.94089	1	0.45724	0.857	0.86984	1	0.64968	0.935
1q gain	34 (21%)	131	0.58682	0.907	0.65326	0.935	0.13827	0.603	0.3097	0.754	0.23485	0.695	0.17379	0.644	0.45104	0.856	0.9958	1	0.54052	0.89	0.87998	1	0.86974	1	0.36566	0.816
2p gain	41 (25%)	124	0.50469	0.877	0.01978	0.266	0.2573	0.702	0.02563	0.304	0.54598	0.895	0.67615	0.947	0.04622	0.407	0.01819	0.266	0.18672	0.671	0.076789	0.493	0.72561	0.968	0.50373	0.877
2q gain	43 (26%)	122	0.092099	0.528	0.057219	0.451	0.12193	0.585	0.062419	0.468	0.7931	0.996	0.58203	0.904	0.088959	0.528	0.00228	0.0802	0.21803	0.695	0.30686	0.75	0.1599	0.637	0.18938	0.676
3p gain	27 (16%)	138	1	1	0.90433	1	0.00062999	0.0378	0.65389	0.935	0.23923	0.695	0.44681	0.854	0.11206	0.567	0.92884	1	0.37909	0.816	0.35612	0.816	0.6574	0.935	0.82422	1
3q gain	34 (21%)	131	0.60508	0.914	0.61421	0.919	8.9999e-05	0.0096	0.86999	1	0.43192	0.85	0.23829	0.695	0.10398	0.549	0.73835	0.973	0.21583	0.695	0.31625	0.761	0.65344	0.935	0.895	1
4p gain	9 (5%)	156	1	1	0.79275	0.996	0.96474	1	0.76641	0.984	0.071579	0.487	0.0319	0.337	0.48386	0.877	0.62824	0.928	0.22543	0.695	0.37365	0.816	0.7454	0.975	0.94957	1
4q gain	5 (3%)	160	0.2963	0.743	0.64923	0.935	0.67776	0.947	NA	NA	0.04528	0.405	0.16211	0.637	0.71278	0.964	1	1	0.88888	1	1	1	NA	NA	NA	NA
5p gain	36 (22%)	129	0.20246	0.685	0.098729	0.539	0.00206	0.0791	0.098429	0.539	0.53437	0.889	0.71258	0.964	0.11434	0.567	4e-05	0.0048	0.19092	0.679	0.92294	1	0.49352	0.877	0.62673	0.928
5q gain	24 (15%)	141	0.24469	0.695	0.086719	0.527	0.0070299	0.161	0.074839	0.489	0.43077	0.85	0.60256	0.913	0.44652	0.854	0.090429	0.528	0.24922	0.697	0.52188	0.879	1	1	0.65407	0.935
6p gain	41 (25%)	124	0.33329	0.787	0.5618	0.895	0.0086199	0.174	0.00364	0.106	0.40237	0.834	0.25612	0.702	0.79808	0.999	0.46789	0.865	0.23887	0.695	0.29867	0.747	0.27762	0.73	0.80592	1
6q gain	36 (22%)	129	0.66964	0.944	0.22761	0.695	0.01619	0.251	0.0068599	0.161	0.63218	0.932	0.45339	0.856	0.6719	0.946	0.50731	0.877	0.34051	0.789	0.58091	0.904	0.20327	0.685	0.56271	0.895
7p gain	102 (62%)	63	0.00234	0.0802	0.00274	0.0877	9.9999e-06	0.0024	0.0032	0.096	0.84133	1	0.0171	0.261	0.00023	0.0221	9.9999e-06	0.0024	0.04138	0.401	0.096809	0.539	0.5926	0.908	0.81531	1
7q gain	85 (52%)	80	0.04839	0.419	0.0079699	0.17	2e-05	0.0032	0.13924	0.603	0.86492	1	0.03999	0.392	0.00414	0.114	0.00206	0.0791	0.49735	0.877	0.8311	1	0.85508	1	0.85576	1
8p gain	42 (25%)	123	0.41656	0.848	0.23665	0.695	0.00181	0.0791	0.51617	0.877	0.18027	0.658	0.03879	0.388	0.51471	0.877	0.34127	0.789	0.81144	1	0.2854	0.732	0.91722	1	0.14106	0.605
8q gain	89 (54%)	76	0.03741	0.382	0.27385	0.727	2e-05	0.0032	0.20955	0.685	0.44462	0.854	0.16263	0.637	0.60292	0.913	0.22104	0.695	0.24549	0.695	0.065859	0.471	0.02047	0.266	0.37244	0.816
9p gain	42 (25%)	123	0.01762	0.264	0.19708	0.685	0.44614	0.854	0.16561	0.637	0.58042	0.904	0.15286	0.626	0.050149	0.425	0.27406	0.727	0.27504	0.727	0.32901	0.78	0.86304	1	0.86703	1
9q gain	33 (20%)	132	0.01492	0.241	0.20985	0.685	0.28199	0.73	0.46955	0.865	0.30306	0.75	0.083769	0.516	0.36887	0.816	0.092329	0.528	0.78445	0.992	0.62074	0.924	0.82926	1	0.93121	1
10p gain	13 (8%)	152	1	1	0.91787	1	0.3368	0.787	0.7157	0.965	0.37057	0.816	0.89474	1	0.52365	0.88	0.12588	0.587	0.65349	0.935	0.91875	1	0.61389	0.919	0.79119	0.996
10q gain	7 (4%)	158	0.51624	0.877	0.081529	0.512	0.25611	0.702	1	1	0.45099	0.856	0.71021	0.964	1	1	0.50316	0.877	0.77137	0.987	0.86164	1	NA	NA	NA	NA
11p gain	32 (19%)	133	0.13463	0.603	0.38867	0.821	0.0083499	0.174	0.42047	0.848	1	1	0.91787	1	0.13409	0.603	0.14458	0.609	0.02139	0.27	0.20883	0.685	0.65373	0.935	0.53797	0.89
11q gain	26 (16%)	139	0.23973	0.695	0.42812	0.849	0.002	0.0791	0.01902	0.266	0.97374	1	0.16737	0.637	0.00274	0.0877	0.00044	0.0378	0.02511	0.304	0.58662	0.907	0.11883	0.578	0.15557	0.63
12p gain	33 (20%)	132	0.68706	0.95	0.48157	0.876	0.23593	0.695	0.72461	0.968	0.16162	0.637	0.69027	0.952	0.083049	0.516	0.20241	0.685	0.37395	0.816	0.55079	0.895	0.27923	0.73	0.86726	1
12q gain	24 (15%)	141	0.77348	0.987	0.51999	0.877	0.74319	0.973	0.30633	0.75	0.28981	0.732	0.50424	0.877	0.0431	0.405	0.51036	0.877	0.22432	0.695	0.74031	0.973	0.053579	0.437	0.94948	1
13q gain	113 (68%)	52	0.2869	0.732	0.38362	0.818	9.9999e-06	0.0024	0.072039	0.487	0.65508	0.935	0.096099	0.539	0.00049	0.0378	0.00060999	0.0378	0.00312	0.096	0.065029	0.471	0.71266	0.964	0.47274	0.868
14q gain	8 (5%)	157	0.83243	1	0.9161	1	0.11404	0.567	0.22689	0.695	0.72261	0.968	0.86386	1	0.49543	0.877	0.91109	1	0.12977	0.599	0.86233	1	NA	NA	NA	NA
15q gain	3 (2%)	162	NA	NA	NA	NA	0.41937	0.848	0.48636	0.877	NA	NA	NA	NA	0.3556	0.816	0.64407	0.935	NA	NA	NA	NA	NA	NA	NA	NA
16p gain	41 (25%)	124	0.14928	0.623	0.85259	1	0.00143	0.0723	0.27252	0.727	0.88795	1	0.34847	0.804	0.11551	0.569	0.36981	0.816	0.15116	0.626	0.67965	0.947	0.33566	0.787	0.98198	1
16q gain	41 (25%)	124	0.052349	0.433	0.59293	0.908	9.9999e-06	0.0024	0.23377	0.695	0.70228	0.964	0.050509	0.425	0.0096099	0.181	0.10439	0.549	0.02028	0.266	0.24489	0.695	0.23189	0.695	0.91562	1
17p gain	8 (5%)	157	0.11006	0.565	0.37857	0.816	0.23105	0.695	0.46831	0.865	0.75979	0.98	0.32831	0.78	0.42101	0.848	0.68469	0.95	0.48844	0.877	0.44399	0.854	NA	NA	NA	NA
17q gain	32 (19%)	133	0.19761	0.685	0.94291	1	0.0069599	0.161	0.42185	0.848	0.65899	0.936	0.40063	0.834	0.36669	0.816	0.49227	0.877	0.055129	0.445	0.46	0.861	0.12039	0.581	0.63798	0.935
18p gain	8 (5%)	157	0.51479	0.877	0.3891	0.821	0.21822	0.695	0.73101	0.969	0.938	1	0.90682	1	0.67936	0.947	0.3854	0.818	0.50274	0.877	0.55794	0.895	1	1	0.8946	1
18q gain	6 (4%)	159	NA	NA	NA	NA	0.79259	0.996	0.38089	0.818	0.86256	1	0.58605	0.907	0.53208	0.887	0.22604	0.695	0.65383	0.935	0.62757	0.928	1	1	0.89154	1
19p gain	33 (20%)	132	0.065649	0.471	0.41856	0.848	0.1059	0.55	0.76625	0.984	0.99036	1	0.53856	0.89	0.56184	0.895	0.02793	0.308	0.13536	0.603	0.95763	1	1	1	0.97247	1
19q gain	32 (19%)	133	0.081539	0.512	0.53191	0.887	0.074539	0.489	0.53038	0.887	0.88332	1	0.87176	1	0.22559	0.695	0.12472	0.586	0.35997	0.816	0.58081	0.904	1	1	0.97331	1
20p gain	109 (66%)	56	0.096949	0.539	0.72789	0.968	0.13786	0.603	0.25131	0.697	0.00447	0.119	0.5501	0.895	0.60662	0.914	0.56418	0.895	0.097689	0.539	0.0453	0.405	0.30629	0.75	0.077099	0.493
20q gain	145 (88%)	20	0.0077999	0.17	0.16154	0.637	0.00062999	0.0378	0.23121	0.695	0.02657	0.304	0.14422	0.609	0.44197	0.854	0.00219	0.0802	0.04396	0.405	0.36225	0.816	0.36524	0.816	1	1
21q gain	10 (6%)	155	0.53986	0.89	0.65777	0.935	0.63283	0.932	1	1	0.077559	0.493	0.30503	0.75	0.94644	1	0.9209	1	0.29212	0.736	0.72351	0.968	NA	NA	NA	NA
22q gain	9 (5%)	156	0.72646	0.968	0.061089	0.465	0.074009	0.489	1	1	0.091309	0.528	0.93474	1	0.35127	0.809	0.19978	0.685	1	1	1	1	NA	NA	NA	NA
xp gain	34 (21%)	131	0.01144	0.208	0.14319	0.609	0.10977	0.565	0.40243	0.834	0.46363	0.863	0.79473	0.996	0.26987	0.725	0.66874	0.944	0.81255	1	0.84921	1	0.8315	1	0.64185	0.935
xq gain	34 (21%)	131	0.15654	0.63	0.3822	0.818	0.045	0.405	0.28887	0.732	0.1293	0.599	0.51114	0.877	0.10436	0.549	0.64405	0.935	0.98129	1	1	1	0.45529	0.856	0.21205	0.69
1p loss	46 (28%)	119	0.6895	0.952	0.02658	0.304	0.051659	0.431	0.18784	0.673	0.3945	0.831	0.17085	0.641	0.3658	0.816	0.16846	0.637	0.44086	0.854	0.61099	0.918	0.55816	0.895	0.56686	0.895
1q loss	26 (16%)	139	0.91241	1	0.057289	0.451	0.25732	0.702	0.02861	0.312	0.97198	1	0.27054	0.725	0.066939	0.471	0.46251	0.862	0.56129	0.895	0.22919	0.695	0.49729	0.877	0.27396	0.727
2p loss	11 (7%)	154	0.63977	0.935	0.75188	0.975	0.00386	0.109	0.48535	0.877	0.58917	0.908	0.40214	0.834	0.52824	0.885	0.058709	0.452	0.43405	0.85	0.6057	0.914	NA	NA	NA	NA
2q loss	6 (4%)	159	1	1	0.56753	0.895	0.053769	0.437	NA	NA	0.28019	0.73	0.51825	0.877	0.81256	1	0.064479	0.471	0.20379	0.685	0.46969	0.865	NA	NA	NA	NA
3p loss	15 (9%)	150	1	1	0.36689	0.816	0.20586	0.685	0.77631	0.989	0.24507	0.695	0.21973	0.695	0.15682	0.63	0.55568	0.895	0.45333	0.856	0.13712	0.603	0.097989	0.539	0.04416	0.405
3q loss	10 (6%)	155	0.51674	0.877	0.79447	0.996	0.19286	0.683	0.40972	0.844	0.23229	0.695	0.51673	0.877	0.1027	0.549	0.21927	0.695	0.494	0.877	0.0095799	0.181	0.41941	0.848	0.36712	0.816
4p loss	59 (36%)	106	0.66435	0.941	0.37553	0.816	0.00182	0.0791	0.02741	0.308	0.42873	0.849	0.23033	0.695	0.71222	0.964	0.57231	0.898	0.97466	1	0.10023	0.541	0.22413	0.695	0.20804	0.685
4q loss	66 (40%)	99	0.77963	0.989	0.26918	0.725	0.00109	0.0616	0.03999	0.392	0.42776	0.849	0.04248	0.405	0.76691	0.984	0.43432	0.85	0.81297	1	0.217	0.695	0.56655	0.895	0.91821	1
5p loss	26 (16%)	139	0.24084	0.695	0.81735	1	0.13743	0.603	0.17881	0.655	0.50611	0.877	0.67732	0.947	0.87929	1	0.12521	0.586	0.7241	0.968	0.57755	0.903	0.16984	0.639	0.24345	0.695
5q loss	40 (24%)	125	0.091249	0.528	0.01158	0.208	0.2176	0.695	0.16739	0.637	0.72882	0.968	0.878	1	0.92652	1	0.22063	0.695	0.91218	1	0.20911	0.685	0.11326	0.567	0.23186	0.695
6p loss	13 (8%)	152	0.54314	0.893	0.92962	1	0.69906	0.961	0.12268	0.586	0.42488	0.848	0.85684	1	0.75105	0.975	0.27691	0.73	0.56385	0.895	0.25267	0.699	NA	NA	NA	NA
6q loss	22 (13%)	143	0.16555	0.637	0.64162	0.935	0.15221	0.626	0.42246	0.848	0.20641	0.685	0.89712	1	0.15443	0.628	0.1515	0.626	0.26176	0.712	0.41218	0.847	0.01217	0.212	0.55644	0.895
7q loss	3 (2%)	162	NA	NA	NA	NA	0.35752	0.816	NA	NA	0.71934	0.967	0.43989	0.854	0.03662	0.378	0.76105	0.981	0.8585	1	1	1	NA	NA	NA	NA
8p loss	73 (44%)	92	0.12372	0.586	0.24795	0.697	0.13341	0.603	0.96505	1	0.14558	0.61	0.57171	0.898	0.02321	0.286	0.11922	0.578	0.89209	1	0.97295	1	0.73347	0.971	0.2308	0.695
8q loss	11 (7%)	154	0.68582	0.95	0.71486	0.965	0.40617	0.839	0.46648	0.865	0.59888	0.913	0.3123	0.755	0.54628	0.895	0.32373	0.771	0.86542	1	0.29957	0.747	0.16698	0.637	0.40559	0.839
9p loss	23 (14%)	142	0.63427	0.932	0.61577	0.919	0.32067	0.766	0.13955	0.603	0.70722	0.964	0.8096	1	0.81264	1	0.51476	0.877	0.3103	0.754	0.04555	0.405	0.71265	0.964	0.03798	0.384
9q loss	23 (14%)	142	0.20785	0.685	0.45019	0.856	0.28179	0.73	0.13789	0.603	0.75474	0.978	0.94736	1	0.51906	0.877	0.19525	0.685	0.070419	0.483	0.00164	0.0787	0.46098	0.861	0.0141	0.241
10p loss	33 (20%)	132	0.14379	0.609	0.17198	0.642	0.13848	0.603	0.068049	0.471	0.091899	0.528	0.04444	0.405	0.19767	0.685	0.45584	0.856	0.83816	1	0.11432	0.567	0.81871	1	0.75051	0.975
10q loss	38 (23%)	127	0.17638	0.649	0.15332	0.626	0.058829	0.452	0.093089	0.529	0.091899	0.528	0.01494	0.241	0.37785	0.816	0.073979	0.489	0.68324	0.95	0.086749	0.527	0.89966	1	0.5365	0.89
11p loss	23 (14%)	142	0.24333	0.695	0.3731	0.816	0.0060199	0.152	0.20345	0.685	0.44081	0.854	0.56173	0.895	0.01931	0.266	0.23476	0.695	0.97706	1	0.74101	0.973	0.60098	0.913	0.28938	0.732
11q loss	30 (18%)	135	0.056019	0.448	0.20654	0.685	0.0069099	0.161	0.02622	0.304	0.94446	1	0.4349	0.85	0.0087099	0.174	0.0076099	0.17	0.20354	0.685	0.37377	0.816	0.41356	0.848	0.66626	0.942
12p loss	22 (13%)	143	0.42352	0.848	0.28482	0.732	0.65565	0.935	0.39878	0.834	0.95142	1	0.55437	0.895	0.75102	0.975	0.43098	0.85	0.45381	0.856	0.77698	0.989	0.067299	0.471	0.50629	0.877
12q loss	19 (12%)	146	0.50076	0.877	0.77023	0.987	0.24025	0.695	0.93077	1	0.21277	0.69	0.6028	0.913	0.83188	1	0.25454	0.702	0.37931	0.816	0.3207	0.766	0.27031	0.725	0.86792	1
13q loss	8 (5%)	157	0.51769	0.877	1	1	0.65488	0.935	0.10588	0.55	0.7062	0.964	0.62717	0.928	1	1	0.49529	0.877	0.17657	0.649	1	1	NA	NA	NA	NA
14q loss	67 (41%)	98	0.50151	0.877	0.24635	0.696	0.01999	0.266	0.57055	0.898	0.95518	1	0.89949	1	0.38447	0.818	0.075319	0.489	0.33628	0.787	0.19935	0.685	0.75113	0.975	0.78121	0.989
15q loss	73 (44%)	92	0.44821	0.855	0.11266	0.567	0.00052999	0.0378	1	1	0.16347	0.637	0.62313	0.926	0.44116	0.854	0.47902	0.873	0.81815	1	0.63521	0.932	0.90591	1	0.7427	0.973
16p loss	9 (5%)	156	0.37641	0.816	0.75767	0.98	0.10021	0.541	0.061589	0.466	0.35896	0.816	0.51834	0.877	0.18672	0.671	0.91237	1	0.56313	0.895	1	1	0.25085	0.697	0.4878	0.877
16q loss	15 (9%)	150	0.28071	0.73	0.67819	0.947	0.04753	0.415	0.33846	0.789	0.49943	0.877	0.87772	1	0.3995	0.834	0.9957	1	0.86736	1	1	1	0.93948	1	0.96279	1
17p loss	107 (65%)	58	0.20643	0.685	0.37497	0.816	0.091969	0.528	0.19651	0.685	0.70922	0.964	0.60156	0.913	0.62052	0.924	0.5908	0.908	0.98121	1	0.39864	0.834	0.28971	0.732	0.66459	0.941
17q loss	26 (16%)	139	0.9043	1	0.73779	0.973	0.02777	0.308	0.089149	0.528	0.79387	0.996	0.13774	0.603	0.11455	0.567	0.33689	0.787	0.86731	1	0.94644	1	0.42074	0.848	0.47554	0.868
18p loss	128 (78%)	37	0.057879	0.452	0.70761	0.964	0.00122	0.0651	0.02598	0.304	0.55172	0.895	0.31837	0.764	0.11651	0.571	0.01508	0.241	0.1671	0.637	0.16282	0.637	0.61585	0.919	0.5902	0.908
18q loss	138 (84%)	27	0.02123	0.27	0.17372	0.644	3e-05	0.00411	0.01168	0.208	0.78006	0.989	0.14025	0.604	0.072749	0.488	0.01938	0.266	0.42487	0.848	0.02904	0.313	0.51443	0.877	0.53777	0.89
19p loss	21 (13%)	144	0.72733	0.968	0.83475	1	0.13478	0.603	0.03037	0.324	0.69892	0.961	0.86633	1	0.5924	0.908	0.56557	0.895	0.37564	0.816	0.01915	0.266	0.96495	1	0.74095	0.973
19q loss	20 (12%)	145	0.83233	1	0.50572	0.877	0.068209	0.471	0.083549	0.516	0.50411	0.877	0.75969	0.98	0.55302	0.895	0.71904	0.967	0.067499	0.471	0.0089699	0.176	1	1	0.74645	0.975
20p loss	23 (14%)	142	1	1	0.95252	1	0.050509	0.425	0.28226	0.73	0.24101	0.695	0.8659	1	0.44097	0.854	0.67406	0.947	0.03232	0.337	0.0223	0.278	0.30505	0.75	0.01446	0.241
21q loss	68 (41%)	97	0.28666	0.732	0.25079	0.697	0.41436	0.848	1	1	0.38281	0.818	0.74083	0.973	0.82175	1	0.68585	0.95	0.01587	0.25	0.18299	0.663	0.22485	0.695	0.068029	0.471
22q loss	58 (35%)	107	0.85379	1	0.3122	0.755	0.065369	0.471	0.77283	0.987	0.65008	0.935	0.30038	0.747	0.33974	0.789	0.16821	0.637	0.0059599	0.152	0.18215	0.662	0.12493	0.586	0.01928	0.266
xp loss	25 (15%)	140	0.2894	0.732	0.89783	1	0.30171	0.748	0.47559	0.868	0.38578	0.818	0.10461	0.549	0.42594	0.848	0.85879	1	0.97701	1	0.5756	0.901	0.56763	0.895	0.77873	0.989
xq loss	24 (15%)	141	0.60781	0.915	0.47475	0.868	0.71002	0.964	0.31623	0.761	0.8686	1	0.29471	0.741	0.56513	0.895	0.95454	1	0.84032	1	0.37126	0.816	0.47446	0.868	0.80613	1
