		Clinical Features	MRNA_CNMF		MRNA_CHIERARCHICAL		CN_CNMF		METHLYATION_CNMF		RPPA_CNMF		RPPA_CHIERARCHICAL		MRNASEQ_CNMF		MRNASEQ_CHIERARCHICAL		MIRSEQ_CNMF		MIRSEQ_CHIERARCHICAL		MIRSEQ_MATURE_CNMF		MIRSEQ_MATURE_CHIERARCHICAL	
	nMutated (%)	nWild-Type	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q	Fisher's exact test_P	Fisher's exact test_Q
APC	108 (89%)	14	0.61532	1	0.96454	1	1	1	NA	NA	0.64502	1	0.47965	0.988	0.41315	0.977	0.086129	0.491	0.059559	0.403	0.41858	0.985	NA	NA	NA	NA
CRIPAK	11 (9%)	111	NA	NA	NA	NA	0.64313	1	0.36134	0.938	0.29813	0.839	0.099139	0.547	0.00178	0.0834	0.00252	0.0864	0.00224	0.0834	0.00126	0.0672	0.26769	0.799	0.76069	1
TP53	91 (75%)	31	0.00078999	0.0474	0.02923	0.344	0.0292	0.344	0.7501	1	0.2428	0.782	0.18672	0.699	0.21954	0.743	0.097989	0.547	0.11599	0.599	0.02418	0.332	0.26783	0.799	0.29517	0.838
NRAS	11 (9%)	111	1	1	0.88883	1	0.52077	1	1	1	0.61541	1	0.00329	0.105	0.55682	1	0.57241	1	0.49093	0.995	0.25183	0.799	0.88299	1	0.057159	0.392
FMN2	14 (11%)	108	0.27826	0.809	0.86002	1	0.03647	0.344	0.50601	0.996	0.44775	0.988	0.10408	0.568	0.0098899	0.198	0.10893	0.581	0.03439	0.344	0.03003	0.344	0.49621	0.995	1	1
SHROOM4	7 (6%)	115	NA	NA	NA	NA	0.46986	0.988	0.55468	1	0.48051	0.988	0.75815	1	0.01592	0.274	0.00226	0.0834	0.01921	0.289	0.00207	0.0834	0.18412	0.699	0.12845	0.629
RPTN	5 (4%)	117	NA	NA	NA	NA	0.74246	1	0.85243	1	0.0364	0.344	0.46178	0.988	0.051399	0.378	0.04623	0.358	0.066529	0.437	0.069949	0.454	1	1	0.41204	0.977
ARID1A	11 (9%)	111	0.3675	0.938	0.39023	0.956	0.46928	0.988	0.354	0.934	0.88526	1	0.1485	0.654	0.8147	1	0.82697	1	0.49187	0.995	0.60632	1	0.66923	1	0.16338	0.674
CDH1	12 (10%)	110	NA	NA	NA	NA	0.76027	1	0.397	0.962	1	1	0.19497	0.699	0.01353	0.26	0.00492	0.131	0.00396	0.119	0.0088699	0.185	0.48044	0.988	0.69142	1
RBM10	6 (5%)	116	0.72337	1	0.98699	1	0.77803	1	NA	NA	0.40873	0.977	0.80603	1	0.48348	0.988	0.92179	1	0.624	1	0.55262	1	NA	NA	NA	NA
HAUS6	5 (4%)	117	NA	NA	NA	NA	0.32886	0.892	1	1	0.47281	0.988	0.36679	0.938	0.081299	0.487	0.1951	0.699	0.19395	0.699	0.19193	0.699	0.88457	1	0.14571	0.654
CTNNB1	19 (16%)	103	0.051989	0.378	0.17924	0.699	0.90023	1	0.75152	1	0.25947	0.799	0.04375	0.345	0.02378	0.332	0.00028	0.0192	0.01661	0.275	0.00026	0.0192	1	1	0.16429	0.674
GABRP	4 (3%)	118	NA	NA	NA	NA	0.66987	1	1	1	NA	NA	NA	NA	0.34611	0.923	0.2773	0.809	0.17967	0.699	0.82412	1	NA	NA	NA	NA
PON3	4 (3%)	118	NA	NA	NA	NA	0.13758	0.637	0.81294	1	NA	NA	NA	NA	0.03345	0.344	0.071049	0.455	0.056539	0.392	0.03361	0.344	0.18523	0.699	0.64479	1
RLIM	4 (3%)	118	NA	NA	NA	NA	0.21267	0.736	0.01927	0.289	0.47003	0.988	0.54012	1	0.0439	0.345	0.04034	0.345	0.46641	0.988	0.51852	1	NA	NA	NA	NA
SMAD2	6 (5%)	116	1	1	0.75088	1	0.21298	0.736	1	1	0.13655	0.637	0.34906	0.926	0.96421	1	0.98874	1	0.95817	1	0.64393	1	NA	NA	NA	NA
TCF7L2	12 (10%)	110	1	1	0.43627	0.988	0.7399	1	0.75061	1	0.57183	1	0.13414	0.637	0.95863	1	0.67087	1	0.44627	0.988	0.84226	1	0.33996	0.912	0.835	1
OXSM	4 (3%)	118	NA	NA	NA	NA	0.90669	1	0.47868	0.988	0.37128	0.938	0.079849	0.485	0.40714	0.977	0.084859	0.491	0.4689	0.988	0.38473	0.952	NA	NA	NA	NA
PCBP1	5 (4%)	117	NA	NA	NA	NA	0.5482	1	0.61876	1	0.26135	0.799	0.64439	1	0.33737	0.91	0.55365	1	0.77588	1	0.58913	1	NA	NA	NA	NA
KRAS	63 (52%)	59	0.18744	0.699	0.0070699	0.162	0.0064599	0.155	0.02787	0.344	0.29891	0.839	0.03718	0.344	0.45684	0.988	0.15865	0.674	0.86321	1	0.053089	0.38	0.68581	1	0.1603	0.674
FLT1	8 (7%)	114	NA	NA	NA	NA	0.83615	1	0.85359	1	0.55128	1	0.32899	0.892	0.02843	0.344	0.21817	0.743	0.15763	0.674	0.38449	0.952	0.12165	0.615	0.58013	1
SLC12A6	6 (5%)	116	NA	NA	NA	NA	0.4543	0.988	0.44688	0.988	0.17181	0.687	0.86992	1	0.04162	0.345	0.15005	0.655	0.26566	0.799	0.32553	0.892	NA	NA	NA	NA
AKAP9	7 (6%)	115	0.77046	1	0.71371	1	0.37498	0.942	0.54864	1	0.24747	0.792	0.26096	0.799	0.050339	0.378	0.03412	0.344	0.93058	1	0.67581	1	NA	NA	NA	NA
VCX2	5 (4%)	117	NA	NA	NA	NA	0.73447	1	0.36271	0.938	0.5707	1	0.14646	0.654	0.03661	0.344	0.12403	0.618	0.04318	0.345	0.0085599	0.185	0.52696	1	0.31961	0.882
ELF3	4 (3%)	118	0.49763	0.995	0.86059	1	0.6736	1	NA	NA	0.36813	0.938	0.15356	0.664	0.27361	0.809	0.14809	0.654	1	1	0.28928	0.831	NA	NA	NA	NA
PIK3CA	36 (30%)	86	0.85521	1	0.98806	1	0.16223	0.674	0.70895	1	0.086959	0.491	0.26462	0.799	9.9999e-06	0.0012	9.9999e-06	0.0012	9.9999e-06	0.0012	9.9999e-06	0.0012	0.11298	0.589	0.24003	0.782
BRAF	13 (11%)	109	0.76906	1	0.86023	1	0.86662	1	0.31274	0.873	0.8449	1	0.01601	0.274	0.00439	0.124	0.1215	0.615	0.13772	0.637	0.03729	0.344	0.90719	1	0.0415	0.345
KIAA1804	10 (8%)	112	0.5132	0.999	0.81255	1	0.02031	0.295	NA	NA	0.5346	1	0.45482	0.988	0.50721	0.996	0.45891	0.988	0.079329	0.485	0.0053999	0.136	NA	NA	NA	NA
ERBB2	9 (7%)	113	1	1	0.84913	1	0.43978	0.988	0.20845	0.736	0.10725	0.578	0.38941	0.956	0.0183	0.289	0.077549	0.483	0.79595	1	0.38202	0.952	0.88309	1	0.5784	1
CDKL5	4 (3%)	118	NA	NA	NA	NA	0.74074	1	1	1	1	1	0.79838	1	0.035	0.344	0.37149	0.938	0.4663	0.988	0.51612	0.999	NA	NA	NA	NA
ZNF354C	5 (4%)	117	NA	NA	NA	NA	0.68134	1	0.29183	0.834	0.04198	0.345	0.70725	1	0.01514	0.274	0.20644	0.734	0.24251	0.782	0.19292	0.699	0.8844	1	0.14658	0.654
LIG1	4 (3%)	118	NA	NA	NA	NA	0.81774	1	0.44795	0.988	0.722	1	0.53948	1	0.02612	0.344	0.12485	0.618	0.082169	0.487	0.03272	0.344	NA	NA	NA	NA
IQCD	3 (2%)	119	NA	NA	NA	NA	0.86377	1	NA	NA	NA	NA	NA	NA	0.086549	0.491	0.27553	0.809	0.50848	0.996	0.57197	1	NA	NA	NA	NA
ZBED4	4 (3%)	118	NA	NA	NA	NA	0.21322	0.736	0.48314	0.988	0.063639	0.424	0.4613	0.988	0.04352	0.345	0.57053	1	0.82833	1	1	1	NA	NA	NA	NA
GMCL1	4 (3%)	118	NA	NA	NA	NA	0.90644	1	0.26535	0.799	0.13809	0.637	0.46168	0.988	0.075879	0.479	0.22948	0.763	0.50597	0.996	0.51567	0.999	0.88358	1	0.2679	0.799
CIR1	3 (2%)	119	NA	NA	NA	NA	0.86498	1	0.35923	0.938	NA	NA	NA	NA	0.11239	0.589	0.23254	0.765	0.16985	0.685	0.1918	0.699	NA	NA	NA	NA
AGL	4 (3%)	118	NA	NA	NA	NA	0.43923	0.988	NA	NA	0.26314	0.799	0.85277	1	0.3174	0.881	0.69686	1	0.54748	1	0.82606	1	NA	NA	NA	NA
FAM123B	10 (8%)	112	0.85652	1	0.41057	0.977	0.22498	0.755	0.50076	0.996	0.4285	0.988	0.42606	0.988	0.65099	1	0.28205	0.816	0.61041	1	0.67325	1	NA	NA	NA	NA
VANGL1	3 (2%)	119	NA	NA	NA	NA	0.39625	0.962	NA	NA	1	1	1	1	0.056969	0.392	0.23041	0.763	0.050539	0.378	0.19491	0.699	NA	NA	NA	NA
CREBBP	10 (8%)	112	NA	NA	NA	NA	0.48377	0.988	0.21976	0.743	0.16827	0.684	0.42825	0.988	2e-05	0.00192	0.03821	0.345	0.13727	0.637	0.17336	0.688	0.89339	1	0.49656	0.995
