This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 81 arm-level events and 10 molecular subtypes across 441 patients, 415 significant findings detected with P value < 0.05 and Q value < 0.25.
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1p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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2q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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3p gain cnv correlated to 'CN_CNMF' and 'RPPA_CNMF'.
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3q gain cnv correlated to 'CN_CNMF'.
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4q gain cnv correlated to 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q gain cnv correlated to 'CN_CNMF'.
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6p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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7q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CHIERARCHICAL'.
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8q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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10p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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10q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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11p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CHIERARCHICAL', and 'MIRSEQ_CNMF'.
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12q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', and 'MIRSEQ_CNMF'.
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13q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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14q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_CNMF'.
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15q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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16p gain cnv correlated to 'CN_CNMF' and 'RPPA_CHIERARCHICAL'.
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16q gain cnv correlated to 'CN_CNMF'.
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17p gain cnv correlated to 'CN_CNMF'.
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17q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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18q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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19p gain cnv correlated to 'CN_CNMF'.
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19q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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21q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q gain cnv correlated to 'CN_CNMF' and 'MIRSEQ_MATURE_CNMF'.
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xp gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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xq gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MRNASEQ_CNMF'.
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1p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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1q loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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2p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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2q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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3p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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3q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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4q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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5q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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6q loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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7p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
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7q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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8p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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8q loss cnv correlated to 'CN_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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9q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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11q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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12q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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13q loss cnv correlated to 'CN_CNMF'.
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14q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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16q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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17q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
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18p loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
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18q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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19q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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20p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', and 'MIRSEQ_CNMF'.
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21q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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22q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
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xp loss cnv correlated to 'CN_CNMF' and 'METHLYATION_CNMF'.
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xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 81 arm-level events and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 415 significant findings detected.
|
Clinical Features |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 6q gain | 64 (15%) | 377 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.0286 (0.0614) |
0.0316 (0.0669) |
0.00052 (0.00202) |
0.00419 (0.012) |
0.00013 (0.000592) |
0.00013 (0.000592) |
0.00135 (0.00458) |
4e-05 (0.000223) |
| 6p gain | 78 (18%) | 363 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.0665 (0.123) |
0.041 (0.0836) |
9e-05 (0.000426) |
0.00509 (0.0145) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.00264 (0.00807) |
1e-05 (6.69e-05) |
| 20p gain | 243 (55%) | 198 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.0887 (0.156) |
0.0145 (0.0359) |
0.00095 (0.00347) |
8e-05 (0.000383) |
6e-05 (0.000306) |
1e-05 (6.69e-05) |
8e-05 (0.000383) |
0.00035 (0.00141) |
| 20q gain | 279 (63%) | 162 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.104 (0.175) |
0.00156 (0.0052) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
8e-05 (0.000383) |
1e-05 (6.69e-05) |
| 17p loss | 164 (37%) | 277 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.0131 (0.0329) |
0.0036 (0.0106) |
0.00026 (0.00109) |
0.00499 (0.0142) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.123 (0.199) |
1e-05 (6.69e-05) |
| 19p loss | 115 (26%) | 326 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.176 (0.262) |
0.00543 (0.0153) |
1e-05 (6.69e-05) |
0.0002 (0.000857) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
4e-05 (0.000223) |
1e-05 (6.69e-05) |
| 1q gain | 103 (23%) | 338 |
1e-05 (6.69e-05) |
0.00015 (0.000675) |
0.131 (0.209) |
0.0216 (0.0483) |
0.00012 (0.000559) |
0.0549 (0.105) |
0.00049 (0.00195) |
0.00114 (0.004) |
0.0012 (0.00415) |
0.00968 (0.0254) |
| 5p gain | 102 (23%) | 339 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.682 (0.744) |
0.104 (0.175) |
3e-05 (0.000175) |
0.00324 (0.00972) |
0.00017 (0.000748) |
1e-05 (6.69e-05) |
0.0125 (0.0317) |
0.00019 (0.000819) |
| 11q gain | 74 (17%) | 367 |
1e-05 (6.69e-05) |
0.00016 (0.000708) |
0.0362 (0.075) |
0.19 (0.28) |
0.138 (0.217) |
0.00128 (0.00441) |
1e-05 (6.69e-05) |
5e-05 (0.00027) |
0.00371 (0.0109) |
0.00634 (0.0175) |
| 18p gain | 84 (19%) | 357 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.299 (0.396) |
0.00031 (0.00128) |
0.00951 (0.025) |
0.314 (0.412) |
2e-05 (0.000126) |
2e-05 (0.000126) |
0.00414 (0.012) |
0.00034 (0.00138) |
| 19q gain | 78 (18%) | 363 |
1e-05 (6.69e-05) |
0.112 (0.185) |
0.017 (0.0404) |
0.0337 (0.0705) |
0.014 (0.0348) |
0.00669 (0.0182) |
0.0251 (0.0551) |
0.0706 (0.129) |
0.0171 (0.0404) |
0.0452 (0.0909) |
| 5q loss | 106 (24%) | 335 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.721 (0.777) |
0.399 (0.492) |
1e-05 (6.69e-05) |
0.0207 (0.0468) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.00016 (0.000708) |
1e-05 (6.69e-05) |
| 9p loss | 150 (34%) | 291 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.611 (0.691) |
0.00035 (0.00141) |
1e-05 (6.69e-05) |
0.247 (0.347) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.0288 (0.0618) |
8e-05 (0.000383) |
| 9q loss | 104 (24%) | 337 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.923 (0.933) |
0.00655 (0.0179) |
0.00025 (0.00105) |
0.345 (0.44) |
3e-05 (0.000175) |
2e-05 (0.000126) |
0.0172 (0.0404) |
0.00206 (0.00652) |
| 12p loss | 63 (14%) | 378 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.29 (0.387) |
0.321 (0.416) |
7e-05 (0.000348) |
0.0135 (0.0337) |
6e-05 (0.000306) |
1e-05 (6.69e-05) |
0.0387 (0.0797) |
3e-05 (0.000175) |
| 15q loss | 90 (20%) | 351 |
1e-05 (6.69e-05) |
0.00172 (0.0056) |
0.0177 (0.0413) |
0.433 (0.522) |
0.00091 (0.00334) |
0.00021 (0.000895) |
0.0175 (0.0411) |
0.00442 (0.0127) |
0.161 (0.248) |
0.00164 (0.0054) |
| 16p loss | 100 (23%) | 341 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.384 (0.479) |
0.418 (0.509) |
1e-05 (6.69e-05) |
0.00285 (0.00861) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
| 16q loss | 115 (26%) | 326 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.955 (0.959) |
0.074 (0.134) |
1e-05 (6.69e-05) |
0.0305 (0.0649) |
1e-05 (6.69e-05) |
2e-05 (0.000126) |
0.00013 (0.000592) |
1e-05 (6.69e-05) |
| 19q loss | 87 (20%) | 354 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.484 (0.575) |
0.068 (0.126) |
1e-05 (6.69e-05) |
0.0229 (0.0509) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.00051 (0.002) |
1e-05 (6.69e-05) |
| 22q loss | 146 (33%) | 295 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.872 (0.893) |
0.00224 (0.00698) |
0.00049 (0.00195) |
0.395 (0.489) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.00213 (0.00669) |
8e-05 (0.000383) |
| 1p gain | 51 (12%) | 390 |
1e-05 (6.69e-05) |
0.00731 (0.0197) |
0.0896 (0.156) |
0.105 (0.176) |
0.00601 (0.0167) |
0.127 (0.203) |
0.00031 (0.00128) |
0.00259 (0.00795) |
0.0261 (0.0571) |
0.0267 (0.0578) |
| 11p gain | 64 (15%) | 377 |
1e-05 (6.69e-05) |
0.00052 (0.00202) |
0.219 (0.315) |
0.253 (0.353) |
0.164 (0.252) |
0.00978 (0.0255) |
6e-05 (0.000306) |
7e-05 (0.000348) |
0.0474 (0.0942) |
0.0462 (0.0924) |
| 13q gain | 154 (35%) | 287 |
1e-05 (6.69e-05) |
7e-05 (0.000348) |
0.0896 (0.156) |
0.817 (0.849) |
0.0146 (0.0359) |
0.283 (0.382) |
0.0013 (0.00446) |
0.00072 (0.00269) |
0.0152 (0.0369) |
0.0204 (0.0466) |
| 3q loss | 54 (12%) | 387 |
1e-05 (6.69e-05) |
6e-05 (0.000306) |
0.083 (0.147) |
0.428 (0.519) |
3e-05 (0.000175) |
0.00828 (0.022) |
0.00513 (0.0145) |
0.00572 (0.016) |
0.272 (0.369) |
0.0007 (0.00262) |
| 4p loss | 167 (38%) | 274 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.497 (0.589) |
0.306 (0.404) |
0.00191 (0.00611) |
0.0555 (0.106) |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.00117 (0.00408) |
1e-05 (6.69e-05) |
| 4q loss | 164 (37%) | 277 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.86 (0.885) |
0.0656 (0.122) |
0.015 (0.0367) |
0.115 (0.188) |
8e-05 (0.000383) |
1e-05 (6.69e-05) |
0.0185 (0.0429) |
1e-05 (6.69e-05) |
| 5p loss | 60 (14%) | 381 |
1e-05 (6.69e-05) |
4e-05 (0.000223) |
0.913 (0.925) |
0.314 (0.412) |
0.00686 (0.0186) |
0.309 (0.408) |
5e-05 (0.00027) |
6e-05 (0.000306) |
0.0237 (0.0525) |
0.00149 (0.00501) |
| 6p loss | 52 (12%) | 389 |
2e-05 (0.000126) |
0.00016 (0.000708) |
0.0154 (0.0373) |
0.834 (0.864) |
0.0451 (0.0909) |
0.0192 (0.044) |
0.124 (0.199) |
0.0143 (0.0354) |
0.245 (0.345) |
0.0266 (0.0577) |
| 10q loss | 67 (15%) | 374 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.633 (0.707) |
0.0189 (0.0437) |
0.00822 (0.0219) |
0.419 (0.51) |
3e-05 (0.000175) |
3e-05 (0.000175) |
0.38 (0.477) |
0.00991 (0.0257) |
| 14q loss | 111 (25%) | 330 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.754 (0.798) |
0.249 (0.347) |
0.00194 (0.00619) |
0.0197 (0.0451) |
0.00011 (0.000515) |
2e-05 (0.000126) |
0.0998 (0.169) |
0.00778 (0.0208) |
| 18q loss | 154 (35%) | 287 |
1e-05 (6.69e-05) |
0.00019 (0.000819) |
0.882 (0.9) |
0.0475 (0.0942) |
0.0811 (0.144) |
0.00062 (0.00237) |
6e-05 (0.000306) |
0.00104 (0.00376) |
0.0773 (0.139) |
0.00105 (0.00376) |
| 2q gain | 66 (15%) | 375 |
1e-05 (6.69e-05) |
0.00903 (0.0238) |
0.407 (0.498) |
0.466 (0.557) |
0.081 (0.144) |
0.00595 (0.0166) |
0.00054 (0.00208) |
0.025 (0.055) |
0.00745 (0.02) |
0.174 (0.261) |
| 21q gain | 21 (5%) | 420 |
0.00013 (0.000592) |
0.00144 (0.00486) |
0.127 (0.203) |
0.363 (0.459) |
0.0172 (0.0405) |
0.0809 (0.144) |
0.0177 (0.0413) |
0.00018 (0.000784) |
0.288 (0.387) |
0.00535 (0.0151) |
| 1p loss | 59 (13%) | 382 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.65 (0.721) |
0.417 (0.509) |
0.0578 (0.109) |
0.099 (0.168) |
0.0125 (0.0317) |
0.0033 (0.00986) |
0.019 (0.0437) |
0.00583 (0.0163) |
| 3p loss | 91 (21%) | 350 |
1e-05 (6.69e-05) |
2e-05 (0.000126) |
0.591 (0.674) |
0.476 (0.566) |
0.0107 (0.0276) |
0.0551 (0.105) |
0.00032 (0.00132) |
0.00114 (0.004) |
0.247 (0.347) |
0.0007 (0.00262) |
| 7p loss | 20 (5%) | 421 |
0.00051 (0.002) |
0.00166 (0.00544) |
0.393 (0.487) |
0.781 (0.823) |
0.0206 (0.0467) |
0.534 (0.624) |
0.00088 (0.00324) |
0.00979 (0.0255) |
0.00417 (0.012) |
0.0733 (0.134) |
| 7q loss | 30 (7%) | 411 |
1e-05 (6.69e-05) |
0.00189 (0.00607) |
0.0434 (0.0878) |
0.7 (0.76) |
0.0353 (0.0734) |
0.774 (0.817) |
0.0164 (0.0391) |
0.0189 (0.0437) |
0.0718 (0.131) |
0.0853 (0.151) |
| 8p loss | 88 (20%) | 353 |
1e-05 (6.69e-05) |
0.00188 (0.00607) |
0.173 (0.26) |
0.159 (0.246) |
0.0489 (0.0962) |
0.0974 (0.167) |
0.00103 (0.00374) |
0.00225 (0.00698) |
0.0555 (0.106) |
1e-05 (6.69e-05) |
| 10p loss | 64 (15%) | 377 |
1e-05 (6.69e-05) |
0.00064 (0.00243) |
0.658 (0.726) |
0.0298 (0.0636) |
0.0682 (0.126) |
0.211 (0.306) |
3e-05 (0.000175) |
0.00014 (0.000634) |
0.286 (0.385) |
0.0131 (0.0329) |
| 12q loss | 52 (12%) | 389 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.661 (0.728) |
0.579 (0.667) |
0.00086 (0.00318) |
0.0745 (0.134) |
0.0393 (0.0805) |
5e-05 (0.00027) |
0.195 (0.286) |
0.00106 (0.00378) |
| 17q loss | 74 (17%) | 367 |
1e-05 (6.69e-05) |
1e-05 (6.69e-05) |
0.865 (0.888) |
0.046 (0.0923) |
0.0111 (0.0285) |
0.264 (0.364) |
0.00065 (0.00246) |
4e-05 (0.000223) |
0.176 (0.262) |
0.0509 (0.0989) |
| 21q loss | 180 (41%) | 261 |
1e-05 (6.69e-05) |
3e-05 (0.000175) |
0.211 (0.306) |
0.32 (0.416) |
0.137 (0.216) |
0.274 (0.372) |
0.00029 (0.00121) |
0.00131 (0.00448) |
0.0064 (0.0175) |
0.00221 (0.00691) |
| 2p gain | 77 (17%) | 364 |
1e-05 (6.69e-05) |
0.00037 (0.00148) |
0.425 (0.517) |
0.315 (0.412) |
0.174 (0.261) |
0.116 (0.189) |
3e-05 (0.000175) |
0.00189 (0.00607) |
0.0513 (0.0991) |
0.0307 (0.0652) |
| 17q gain | 62 (14%) | 379 |
5e-05 (0.00027) |
0.048 (0.0951) |
0.674 (0.739) |
0.602 (0.684) |
0.33 (0.424) |
0.0419 (0.0851) |
0.0162 (0.0387) |
0.247 (0.347) |
0.155 (0.242) |
0.0259 (0.0567) |
| 2q loss | 33 (7%) | 408 |
1e-05 (6.69e-05) |
0.00051 (0.002) |
0.267 (0.366) |
0.508 (0.596) |
0.015 (0.0367) |
0.547 (0.637) |
0.00349 (0.0104) |
0.0241 (0.0531) |
0.652 (0.723) |
0.264 (0.364) |
| 11p loss | 62 (14%) | 379 |
1e-05 (6.69e-05) |
0.00132 (0.00449) |
0.074 (0.134) |
0.0326 (0.0685) |
0.234 (0.333) |
0.539 (0.629) |
0.15 (0.236) |
0.0122 (0.0311) |
0.382 (0.477) |
0.0131 (0.0329) |
| 20p loss | 22 (5%) | 419 |
0.00241 (0.00742) |
0.0157 (0.0378) |
0.00637 (0.0175) |
0.685 (0.746) |
0.00153 (0.00512) |
0.224 (0.321) |
0.0386 (0.0797) |
0.589 (0.674) |
0.635 (0.708) |
0.886 (0.903) |
| 7p gain | 197 (45%) | 244 |
1e-05 (6.69e-05) |
0.00033 (0.00135) |
0.346 (0.44) |
0.105 (0.176) |
0.267 (0.366) |
0.2 (0.293) |
0.11 (0.183) |
0.0124 (0.0317) |
0.791 (0.831) |
0.0016 (0.00529) |
| 8q gain | 237 (54%) | 204 |
0.00893 (0.0236) |
0.0131 (0.0329) |
0.618 (0.695) |
0.556 (0.646) |
0.0499 (0.0975) |
0.562 (0.649) |
0.0157 (0.0378) |
0.105 (0.176) |
0.443 (0.532) |
0.29 (0.387) |
| 10p gain | 98 (22%) | 343 |
1e-05 (6.69e-05) |
0.00011 (0.000515) |
0.763 (0.807) |
0.591 (0.674) |
0.00391 (0.0114) |
0.169 (0.256) |
0.393 (0.487) |
0.00169 (0.00552) |
0.323 (0.417) |
0.0592 (0.111) |
| 15q gain | 39 (9%) | 402 |
6e-05 (0.000306) |
7e-05 (0.000348) |
0.357 (0.452) |
0.0512 (0.0991) |
0.0499 (0.0975) |
0.0863 (0.152) |
0.0894 (0.156) |
0.00306 (0.00921) |
0.435 (0.523) |
0.172 (0.26) |
| 18q gain | 54 (12%) | 387 |
0.00615 (0.017) |
0.00283 (0.00859) |
0.82 (0.851) |
0.0518 (0.0999) |
0.297 (0.396) |
0.5 (0.59) |
0.0274 (0.059) |
0.0266 (0.0577) |
0.401 (0.494) |
0.257 (0.356) |
| 2p loss | 26 (6%) | 415 |
5e-05 (0.00027) |
0.00023 (0.000975) |
0.122 (0.198) |
0.29 (0.387) |
0.0212 (0.0477) |
0.681 (0.744) |
0.0415 (0.0844) |
0.133 (0.21) |
0.591 (0.674) |
0.193 (0.284) |
| xq loss | 50 (11%) | 391 |
1e-05 (6.69e-05) |
0.0041 (0.0119) |
0.984 (0.986) |
0.133 (0.21) |
0.107 (0.179) |
0.522 (0.611) |
0.0536 (0.103) |
0.0991 (0.168) |
0.021 (0.0474) |
0.0465 (0.0928) |
| 4q gain | 16 (4%) | 425 |
0.432 (0.521) |
0.669 (0.735) |
0.876 (0.896) |
0.111 (0.184) |
0.0339 (0.0708) |
0.656 (0.725) |
0.732 (0.782) |
0.0321 (0.0678) |
0.343 (0.438) |
0.0486 (0.096) |
| 7q gain | 169 (38%) | 272 |
1e-05 (6.69e-05) |
0.00061 (0.00234) |
0.386 (0.48) |
0.371 (0.468) |
0.289 (0.387) |
0.414 (0.506) |
0.26 (0.359) |
0.254 (0.354) |
0.721 (0.777) |
0.0296 (0.0633) |
| 8p gain | 182 (41%) | 259 |
9e-05 (0.000426) |
0.0443 (0.0895) |
0.188 (0.278) |
0.397 (0.49) |
0.631 (0.706) |
0.0368 (0.076) |
0.175 (0.261) |
0.613 (0.692) |
0.335 (0.429) |
0.752 (0.798) |
| 10q gain | 70 (16%) | 371 |
1e-05 (6.69e-05) |
0.0401 (0.0821) |
0.508 (0.596) |
0.688 (0.749) |
0.0167 (0.0397) |
0.0988 (0.168) |
0.729 (0.781) |
0.293 (0.391) |
0.838 (0.867) |
0.0641 (0.119) |
| 12p gain | 90 (20%) | 351 |
0.00018 (0.000784) |
0.201 (0.293) |
0.165 (0.253) |
0.469 (0.56) |
0.108 (0.18) |
0.0154 (0.0373) |
0.0107 (0.0276) |
0.356 (0.451) |
0.163 (0.25) |
0.119 (0.193) |
| 12q gain | 77 (17%) | 364 |
0.00363 (0.0107) |
0.0938 (0.162) |
0.00212 (0.00668) |
0.366 (0.462) |
0.908 (0.922) |
0.0739 (0.134) |
0.0495 (0.0971) |
0.608 (0.689) |
0.354 (0.449) |
0.334 (0.429) |
| xp gain | 48 (11%) | 393 |
1e-05 (6.69e-05) |
0.00105 (0.00376) |
0.802 (0.84) |
0.314 (0.412) |
0.0148 (0.0363) |
0.607 (0.689) |
0.061 (0.114) |
0.33 (0.424) |
0.0506 (0.0985) |
0.109 (0.182) |
| xq gain | 56 (13%) | 385 |
1e-05 (6.69e-05) |
0.0267 (0.0578) |
0.87 (0.892) |
0.814 (0.848) |
0.00732 (0.0197) |
0.811 (0.846) |
0.225 (0.321) |
0.558 (0.646) |
0.67 (0.735) |
0.231 (0.329) |
| 8q loss | 33 (7%) | 408 |
0.00085 (0.00316) |
0.592 (0.674) |
0.586 (0.673) |
0.505 (0.595) |
0.706 (0.766) |
0.941 (0.947) |
0.0488 (0.0962) |
0.329 (0.424) |
0.103 (0.174) |
0.0225 (0.0501) |
| 11q loss | 61 (14%) | 380 |
6e-05 (0.000306) |
0.0205 (0.0466) |
0.928 (0.936) |
0.353 (0.448) |
0.725 (0.779) |
0.839 (0.867) |
0.0976 (0.167) |
0.22 (0.316) |
0.318 (0.414) |
0.0324 (0.0681) |
| 3p gain | 53 (12%) | 388 |
0.00199 (0.00632) |
0.407 (0.498) |
0.016 (0.0383) |
0.0865 (0.152) |
0.584 (0.672) |
0.319 (0.414) |
0.247 (0.347) |
0.31 (0.408) |
0.119 (0.193) |
0.307 (0.406) |
| 14q gain | 29 (7%) | 412 |
6e-05 (0.000306) |
0.152 (0.237) |
0.545 (0.635) |
0.737 (0.785) |
0.317 (0.413) |
0.342 (0.438) |
0.00159 (0.00528) |
0.381 (0.477) |
0.151 (0.237) |
0.305 (0.404) |
| 16p gain | 59 (13%) | 382 |
0.00113 (0.004) |
0.0909 (0.158) |
0.499 (0.59) |
0.0229 (0.0509) |
0.0974 (0.167) |
0.467 (0.558) |
0.753 (0.798) |
0.794 (0.832) |
0.475 (0.566) |
0.619 (0.696) |
| 22q gain | 32 (7%) | 409 |
0.00227 (0.00702) |
0.121 (0.196) |
0.598 (0.68) |
0.818 (0.85) |
0.309 (0.408) |
0.714 (0.772) |
0.0586 (0.111) |
0.554 (0.644) |
0.0212 (0.0477) |
0.698 (0.759) |
| 1q loss | 28 (6%) | 413 |
3e-05 (0.000175) |
4e-05 (0.000223) |
0.794 (0.832) |
0.384 (0.479) |
0.282 (0.381) |
0.188 (0.277) |
0.134 (0.211) |
0.163 (0.251) |
0.559 (0.646) |
0.2 (0.292) |
| 6q loss | 70 (16%) | 371 |
1e-05 (6.69e-05) |
0.0012 (0.00415) |
0.0744 (0.134) |
0.928 (0.936) |
0.114 (0.187) |
0.238 (0.337) |
0.646 (0.718) |
0.0683 (0.126) |
0.431 (0.521) |
0.0563 (0.107) |
| 18p loss | 119 (27%) | 322 |
2e-05 (0.000126) |
0.167 (0.254) |
0.617 (0.695) |
0.158 (0.246) |
0.727 (0.78) |
0.0361 (0.075) |
0.0801 (0.144) |
0.266 (0.366) |
0.451 (0.54) |
0.218 (0.315) |
| xp loss | 59 (13%) | 382 |
1e-05 (6.69e-05) |
0.0039 (0.0114) |
0.887 (0.903) |
0.268 (0.366) |
0.283 (0.382) |
0.938 (0.945) |
0.133 (0.21) |
0.149 (0.234) |
0.16 (0.247) |
0.219 (0.315) |
| 3q gain | 93 (21%) | 348 |
1e-05 (6.69e-05) |
0.12 (0.195) |
0.0593 (0.111) |
0.23 (0.328) |
0.0881 (0.155) |
0.396 (0.49) |
0.114 (0.187) |
0.128 (0.204) |
0.212 (0.308) |
0.176 (0.262) |
| 5q gain | 44 (10%) | 397 |
0.0107 (0.0276) |
0.325 (0.419) |
0.641 (0.714) |
0.202 (0.294) |
0.268 (0.366) |
0.38 (0.477) |
0.587 (0.674) |
0.406 (0.498) |
0.0897 (0.156) |
0.377 (0.474) |
| 16q gain | 47 (11%) | 394 |
0.00268 (0.00816) |
0.809 (0.844) |
0.919 (0.93) |
0.167 (0.254) |
0.175 (0.261) |
0.126 (0.203) |
0.734 (0.783) |
0.75 (0.798) |
0.248 (0.347) |
0.157 (0.244) |
| 17p gain | 29 (7%) | 412 |
0.00113 (0.004) |
0.0528 (0.102) |
0.854 (0.88) |
0.9 (0.915) |
0.111 (0.183) |
0.093 (0.161) |
0.121 (0.196) |
0.282 (0.382) |
0.173 (0.261) |
0.576 (0.665) |
| 19p gain | 54 (12%) | 387 |
4e-05 (0.000223) |
0.654 (0.723) |
0.0704 (0.129) |
0.168 (0.255) |
0.61 (0.69) |
0.243 (0.344) |
0.503 (0.593) |
0.723 (0.778) |
0.843 (0.87) |
0.428 (0.519) |
| 13q loss | 36 (8%) | 405 |
0.00354 (0.0105) |
0.732 (0.782) |
0.405 (0.497) |
0.0834 (0.148) |
0.27 (0.367) |
0.863 (0.887) |
0.67 (0.735) |
0.626 (0.702) |
0.778 (0.82) |
0.238 (0.338) |
| 4p gain | 21 (5%) | 420 |
0.0787 (0.141) |
0.708 (0.767) |
0.166 (0.254) |
0.063 (0.118) |
0.255 (0.354) |
0.261 (0.361) |
0.881 (0.9) |
0.0936 (0.162) |
0.255 (0.354) |
0.0602 (0.113) |
| 9p gain | 60 (14%) | 381 |
0.0942 (0.162) |
0.986 (0.987) |
0.951 (0.955) |
0.782 (0.823) |
0.715 (0.772) |
0.177 (0.262) |
0.749 (0.797) |
0.646 (0.718) |
0.433 (0.522) |
0.223 (0.319) |
| 9q gain | 78 (18%) | 363 |
0.215 (0.312) |
0.627 (0.702) |
0.491 (0.583) |
0.68 (0.744) |
0.514 (0.603) |
0.133 (0.211) |
1 (1.00) |
0.807 (0.844) |
0.185 (0.274) |
0.169 (0.256) |
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S1. Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 1P GAIN MUTATED | 27 | 5 | 4 | 12 | 3 |
| 1P GAIN WILD-TYPE | 96 | 182 | 32 | 64 | 16 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00731 (Fisher's exact test), Q value = 0.02
Table S2. Gene #1: '1p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 1P GAIN MUTATED | 23 | 15 | 1 | 7 |
| 1P GAIN WILD-TYPE | 101 | 106 | 41 | 99 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00601 (Fisher's exact test), Q value = 0.017
Table S3. Gene #1: '1p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 1P GAIN MUTATED | 3 | 2 | 6 | 4 | 14 |
| 1P GAIN WILD-TYPE | 59 | 60 | 38 | 36 | 50 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0013
Table S4. Gene #1: '1p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 1P GAIN MUTATED | 13 | 9 | 28 |
| 1P GAIN WILD-TYPE | 159 | 121 | 104 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00259 (Fisher's exact test), Q value = 0.0079
Table S5. Gene #1: '1p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 1P GAIN MUTATED | 21 | 6 | 23 |
| 1P GAIN WILD-TYPE | 222 | 76 | 86 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0261 (Fisher's exact test), Q value = 0.057
Table S6. Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 1P GAIN MUTATED | 15 | 3 | 2 | 5 | 4 | 7 |
| 1P GAIN WILD-TYPE | 58 | 54 | 57 | 55 | 29 | 52 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0267 (Fisher's exact test), Q value = 0.058
Table S7. Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 1P GAIN MUTATED | 13 | 3 | 0 | 6 | 5 | 9 |
| 1P GAIN WILD-TYPE | 71 | 54 | 35 | 70 | 23 | 52 |
Figure S7. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S8. Gene #2: '1q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 1Q GAIN MUTATED | 53 | 12 | 10 | 22 | 6 |
| 1Q GAIN WILD-TYPE | 70 | 175 | 26 | 54 | 13 |
Figure S8. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00015 (Fisher's exact test), Q value = 0.00067
Table S9. Gene #2: '1q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 1Q GAIN MUTATED | 44 | 31 | 5 | 13 |
| 1Q GAIN WILD-TYPE | 80 | 90 | 37 | 93 |
Figure S9. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0216 (Fisher's exact test), Q value = 0.048
Table S10. Gene #2: '1q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 1Q GAIN MUTATED | 40 | 13 | 20 | 9 |
| 1Q GAIN WILD-TYPE | 100 | 45 | 58 | 71 |
Figure S10. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00012 (Fisher's exact test), Q value = 0.00056
Table S11. Gene #2: '1q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 1Q GAIN MUTATED | 9 | 7 | 9 | 11 | 29 |
| 1Q GAIN WILD-TYPE | 53 | 55 | 35 | 29 | 35 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00049 (Fisher's exact test), Q value = 0.0019
Table S12. Gene #2: '1q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 1Q GAIN MUTATED | 30 | 24 | 47 |
| 1Q GAIN WILD-TYPE | 142 | 106 | 85 |
Figure S12. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00114 (Fisher's exact test), Q value = 0.004
Table S13. Gene #2: '1q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 1Q GAIN MUTATED | 45 | 16 | 40 |
| 1Q GAIN WILD-TYPE | 198 | 66 | 69 |
Figure S13. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0012 (Fisher's exact test), Q value = 0.0042
Table S14. Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 1Q GAIN MUTATED | 30 | 7 | 11 | 10 | 10 | 10 |
| 1Q GAIN WILD-TYPE | 43 | 50 | 48 | 50 | 23 | 49 |
Figure S14. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00968 (Fisher's exact test), Q value = 0.025
Table S15. Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 1Q GAIN MUTATED | 23 | 9 | 2 | 16 | 6 | 22 |
| 1Q GAIN WILD-TYPE | 61 | 48 | 33 | 60 | 22 | 39 |
Figure S15. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S16. Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 2P GAIN MUTATED | 35 | 8 | 12 | 16 | 6 |
| 2P GAIN WILD-TYPE | 88 | 179 | 24 | 60 | 13 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0015
Table S17. Gene #3: '2p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 2P GAIN MUTATED | 35 | 23 | 5 | 8 |
| 2P GAIN WILD-TYPE | 89 | 98 | 37 | 98 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S18. Gene #3: '2p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 2P GAIN MUTATED | 25 | 11 | 40 |
| 2P GAIN WILD-TYPE | 147 | 119 | 92 |
Figure S18. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00189 (Fisher's exact test), Q value = 0.0061
Table S19. Gene #3: '2p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 2P GAIN MUTATED | 37 | 8 | 31 |
| 2P GAIN WILD-TYPE | 206 | 74 | 78 |
Figure S19. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0307 (Fisher's exact test), Q value = 0.065
Table S20. Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 2P GAIN MUTATED | 20 | 4 | 2 | 16 | 4 | 13 |
| 2P GAIN WILD-TYPE | 64 | 53 | 33 | 60 | 24 | 48 |
Figure S20. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S21. Gene #4: '2q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 2Q GAIN MUTATED | 28 | 8 | 10 | 15 | 5 |
| 2Q GAIN WILD-TYPE | 95 | 179 | 26 | 61 | 14 |
Figure S21. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00903 (Fisher's exact test), Q value = 0.024
Table S22. Gene #4: '2q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 2Q GAIN MUTATED | 29 | 19 | 5 | 8 |
| 2Q GAIN WILD-TYPE | 95 | 102 | 37 | 98 |
Figure S22. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00595 (Fisher's exact test), Q value = 0.017
Table S23. Gene #4: '2q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 2Q GAIN MUTATED | 26 | 5 | 10 |
| 2Q GAIN WILD-TYPE | 84 | 52 | 95 |
Figure S23. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00054 (Fisher's exact test), Q value = 0.0021
Table S24. Gene #4: '2q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 2Q GAIN MUTATED | 21 | 11 | 33 |
| 2Q GAIN WILD-TYPE | 151 | 119 | 99 |
Figure S24. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.025 (Fisher's exact test), Q value = 0.055
Table S25. Gene #4: '2q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 2Q GAIN MUTATED | 32 | 8 | 25 |
| 2Q GAIN WILD-TYPE | 211 | 74 | 84 |
Figure S25. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00745 (Fisher's exact test), Q value = 0.02
Table S26. Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 2Q GAIN MUTATED | 18 | 5 | 7 | 4 | 10 | 9 |
| 2Q GAIN WILD-TYPE | 55 | 52 | 52 | 56 | 23 | 50 |
Figure S26. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00199 (Fisher's exact test), Q value = 0.0063
Table S27. Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 3P GAIN MUTATED | 18 | 11 | 6 | 12 | 6 |
| 3P GAIN WILD-TYPE | 105 | 176 | 30 | 64 | 13 |
Figure S27. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.016 (Fisher's exact test), Q value = 0.038
Table S28. Gene #5: '3p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 3P GAIN MUTATED | 6 | 18 | 7 | 11 | 2 |
| 3P GAIN WILD-TYPE | 24 | 74 | 75 | 82 | 57 |
Figure S28. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S29. Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 3Q GAIN MUTATED | 27 | 20 | 11 | 25 | 10 |
| 3Q GAIN WILD-TYPE | 96 | 167 | 25 | 51 | 9 |
Figure S29. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0339 (Fisher's exact test), Q value = 0.071
Table S30. Gene #8: '4q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 4Q GAIN MUTATED | 0 | 0 | 2 | 3 | 1 |
| 4Q GAIN WILD-TYPE | 62 | 62 | 42 | 37 | 63 |
Figure S30. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0321 (Fisher's exact test), Q value = 0.068
Table S31. Gene #8: '4q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 4Q GAIN MUTATED | 14 | 0 | 2 |
| 4Q GAIN WILD-TYPE | 229 | 82 | 107 |
Figure S31. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0486 (Fisher's exact test), Q value = 0.096
Table S32. Gene #8: '4q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 4Q GAIN MUTATED | 6 | 0 | 1 | 5 | 0 | 0 |
| 4Q GAIN WILD-TYPE | 78 | 57 | 34 | 71 | 28 | 61 |
Figure S32. Get High-res Image Gene #8: '4q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S33. Gene #9: '5p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 5P GAIN MUTATED | 59 | 16 | 7 | 17 | 3 |
| 5P GAIN WILD-TYPE | 64 | 171 | 29 | 59 | 16 |
Figure S33. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S34. Gene #9: '5p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 5P GAIN MUTATED | 49 | 19 | 6 | 14 |
| 5P GAIN WILD-TYPE | 75 | 102 | 36 | 92 |
Figure S34. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S35. Gene #9: '5p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 5P GAIN MUTATED | 10 | 5 | 8 | 8 | 29 |
| 5P GAIN WILD-TYPE | 52 | 57 | 36 | 32 | 35 |
Figure S35. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00324 (Fisher's exact test), Q value = 0.0097
Table S36. Gene #9: '5p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 5P GAIN MUTATED | 34 | 5 | 21 |
| 5P GAIN WILD-TYPE | 76 | 52 | 84 |
Figure S36. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00017 (Fisher's exact test), Q value = 0.00075
Table S37. Gene #9: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 5P GAIN MUTATED | 38 | 17 | 46 |
| 5P GAIN WILD-TYPE | 134 | 113 | 86 |
Figure S37. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S38. Gene #9: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 5P GAIN MUTATED | 46 | 9 | 46 |
| 5P GAIN WILD-TYPE | 197 | 73 | 63 |
Figure S38. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0125 (Fisher's exact test), Q value = 0.032
Table S39. Gene #9: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 5P GAIN MUTATED | 25 | 10 | 15 | 14 | 9 | 5 |
| 5P GAIN WILD-TYPE | 48 | 47 | 44 | 46 | 24 | 54 |
Figure S39. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.00082
Table S40. Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 5P GAIN MUTATED | 19 | 4 | 5 | 20 | 4 | 26 |
| 5P GAIN WILD-TYPE | 65 | 53 | 30 | 56 | 24 | 35 |
Figure S40. Get High-res Image Gene #9: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0107 (Fisher's exact test), Q value = 0.028
Table S41. Gene #10: '5q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 5Q GAIN MUTATED | 20 | 11 | 1 | 11 | 1 |
| 5Q GAIN WILD-TYPE | 103 | 176 | 35 | 65 | 18 |
Figure S41. Get High-res Image Gene #10: '5q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S42. Gene #11: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 6P GAIN MUTATED | 53 | 6 | 1 | 14 | 4 |
| 6P GAIN WILD-TYPE | 70 | 181 | 35 | 62 | 15 |
Figure S42. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S43. Gene #11: '6p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 6P GAIN MUTATED | 45 | 13 | 1 | 6 |
| 6P GAIN WILD-TYPE | 79 | 108 | 41 | 100 |
Figure S43. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.041 (Fisher's exact test), Q value = 0.084
Table S44. Gene #11: '6p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 6P GAIN MUTATED | 32 | 8 | 16 | 7 |
| 6P GAIN WILD-TYPE | 108 | 50 | 62 | 73 |
Figure S44. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00043
Table S45. Gene #11: '6p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 6P GAIN MUTATED | 9 | 4 | 6 | 5 | 24 |
| 6P GAIN WILD-TYPE | 53 | 58 | 38 | 35 | 40 |
Figure S45. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00509 (Fisher's exact test), Q value = 0.014
Table S46. Gene #11: '6p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 6P GAIN MUTATED | 27 | 3 | 18 |
| 6P GAIN WILD-TYPE | 83 | 54 | 87 |
Figure S46. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S47. Gene #11: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 6P GAIN MUTATED | 26 | 10 | 41 |
| 6P GAIN WILD-TYPE | 146 | 120 | 91 |
Figure S47. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S48. Gene #11: '6p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 6P GAIN MUTATED | 33 | 6 | 38 |
| 6P GAIN WILD-TYPE | 210 | 76 | 71 |
Figure S48. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00264 (Fisher's exact test), Q value = 0.0081
Table S49. Gene #11: '6p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 6P GAIN MUTATED | 24 | 7 | 7 | 9 | 6 | 4 |
| 6P GAIN WILD-TYPE | 49 | 50 | 52 | 51 | 27 | 55 |
Figure S49. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S50. Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 6P GAIN MUTATED | 18 | 3 | 1 | 10 | 1 | 24 |
| 6P GAIN WILD-TYPE | 66 | 54 | 34 | 66 | 27 | 37 |
Figure S50. Get High-res Image Gene #11: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S51. Gene #12: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 6Q GAIN MUTATED | 45 | 5 | 0 | 11 | 3 |
| 6Q GAIN WILD-TYPE | 78 | 182 | 36 | 65 | 16 |
Figure S51. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S52. Gene #12: '6q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 6Q GAIN MUTATED | 36 | 12 | 1 | 4 |
| 6Q GAIN WILD-TYPE | 88 | 109 | 41 | 102 |
Figure S52. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0286 (Fisher's exact test), Q value = 0.061
Table S53. Gene #12: '6q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 6Q GAIN MUTATED | 4 | 20 | 17 | 7 | 6 |
| 6Q GAIN WILD-TYPE | 26 | 72 | 65 | 86 | 53 |
Figure S53. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0316 (Fisher's exact test), Q value = 0.067
Table S54. Gene #12: '6q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 6Q GAIN MUTATED | 29 | 8 | 12 | 5 |
| 6Q GAIN WILD-TYPE | 111 | 50 | 66 | 75 |
Figure S54. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00052 (Fisher's exact test), Q value = 0.002
Table S55. Gene #12: '6q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 6Q GAIN MUTATED | 5 | 4 | 5 | 5 | 21 |
| 6Q GAIN WILD-TYPE | 57 | 58 | 39 | 35 | 43 |
Figure S55. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00419 (Fisher's exact test), Q value = 0.012
Table S56. Gene #12: '6q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 6Q GAIN MUTATED | 24 | 2 | 14 |
| 6Q GAIN WILD-TYPE | 86 | 55 | 91 |
Figure S56. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00059
Table S57. Gene #12: '6q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 6Q GAIN MUTATED | 23 | 8 | 32 |
| 6Q GAIN WILD-TYPE | 149 | 122 | 100 |
Figure S57. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00013 (Fisher's exact test), Q value = 0.00059
Table S58. Gene #12: '6q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 6Q GAIN MUTATED | 29 | 5 | 29 |
| 6Q GAIN WILD-TYPE | 214 | 77 | 80 |
Figure S58. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00135 (Fisher's exact test), Q value = 0.0046
Table S59. Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 6Q GAIN MUTATED | 21 | 5 | 4 | 9 | 5 | 3 |
| 6Q GAIN WILD-TYPE | 52 | 52 | 55 | 51 | 28 | 56 |
Figure S59. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S60. Gene #12: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 6Q GAIN MUTATED | 15 | 2 | 1 | 10 | 0 | 19 |
| 6Q GAIN WILD-TYPE | 69 | 55 | 34 | 66 | 28 | 42 |
Figure S60. Get High-res Image Gene #12: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S61. Gene #13: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 7P GAIN MUTATED | 67 | 44 | 34 | 40 | 12 |
| 7P GAIN WILD-TYPE | 56 | 143 | 2 | 36 | 7 |
Figure S61. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00033 (Fisher's exact test), Q value = 0.0013
Table S62. Gene #13: '7p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 7P GAIN MUTATED | 69 | 59 | 19 | 30 |
| 7P GAIN WILD-TYPE | 55 | 62 | 23 | 76 |
Figure S62. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0124 (Fisher's exact test), Q value = 0.032
Table S63. Gene #13: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 7P GAIN MUTATED | 108 | 26 | 58 |
| 7P GAIN WILD-TYPE | 135 | 56 | 51 |
Figure S63. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0016 (Fisher's exact test), Q value = 0.0053
Table S64. Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 7P GAIN MUTATED | 42 | 12 | 12 | 40 | 15 | 30 |
| 7P GAIN WILD-TYPE | 42 | 45 | 23 | 36 | 13 | 31 |
Figure S64. Get High-res Image Gene #13: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S65. Gene #14: '7q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 7Q GAIN MUTATED | 53 | 43 | 34 | 30 | 9 |
| 7Q GAIN WILD-TYPE | 70 | 144 | 2 | 46 | 10 |
Figure S65. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00061 (Fisher's exact test), Q value = 0.0023
Table S66. Gene #14: '7q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 7Q GAIN MUTATED | 58 | 46 | 20 | 24 |
| 7Q GAIN WILD-TYPE | 66 | 75 | 22 | 82 |
Figure S66. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0296 (Fisher's exact test), Q value = 0.063
Table S67. Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 7Q GAIN MUTATED | 36 | 11 | 11 | 31 | 14 | 22 |
| 7Q GAIN WILD-TYPE | 48 | 46 | 24 | 45 | 14 | 39 |
Figure S67. Get High-res Image Gene #14: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 9e-05 (Fisher's exact test), Q value = 0.00043
Table S68. Gene #15: '8p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 8P GAIN MUTATED | 44 | 82 | 16 | 23 | 17 |
| 8P GAIN WILD-TYPE | 79 | 105 | 20 | 53 | 2 |
Figure S68. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0443 (Fisher's exact test), Q value = 0.09
Table S69. Gene #15: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 8P GAIN MUTATED | 44 | 61 | 16 | 36 |
| 8P GAIN WILD-TYPE | 80 | 60 | 26 | 70 |
Figure S69. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0368 (Fisher's exact test), Q value = 0.076
Table S70. Gene #15: '8p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 8P GAIN MUTATED | 34 | 26 | 49 |
| 8P GAIN WILD-TYPE | 76 | 31 | 56 |
Figure S70. Get High-res Image Gene #15: '8p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00893 (Fisher's exact test), Q value = 0.024
Table S71. Gene #16: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 8Q GAIN MUTATED | 71 | 93 | 19 | 37 | 17 |
| 8Q GAIN WILD-TYPE | 52 | 94 | 17 | 39 | 2 |
Figure S71. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0131 (Fisher's exact test), Q value = 0.033
Table S72. Gene #16: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 8Q GAIN MUTATED | 69 | 75 | 17 | 46 |
| 8Q GAIN WILD-TYPE | 55 | 46 | 25 | 60 |
Figure S72. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0499 (Fisher's exact test), Q value = 0.097
Table S73. Gene #16: '8q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 8Q GAIN MUTATED | 32 | 29 | 17 | 24 | 42 |
| 8Q GAIN WILD-TYPE | 30 | 33 | 27 | 16 | 22 |
Figure S73. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0157 (Fisher's exact test), Q value = 0.038
Table S74. Gene #16: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 8Q GAIN MUTATED | 95 | 57 | 81 |
| 8Q GAIN WILD-TYPE | 77 | 73 | 51 |
Figure S74. Get High-res Image Gene #16: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S75. Gene #19: '10p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 10P GAIN MUTATED | 39 | 9 | 14 | 35 | 1 |
| 10P GAIN WILD-TYPE | 84 | 178 | 22 | 41 | 18 |
Figure S75. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00052
Table S76. Gene #19: '10p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 10P GAIN MUTATED | 43 | 24 | 2 | 17 |
| 10P GAIN WILD-TYPE | 81 | 97 | 40 | 89 |
Figure S76. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00391 (Fisher's exact test), Q value = 0.011
Table S77. Gene #19: '10p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 10P GAIN MUTATED | 10 | 13 | 7 | 7 | 27 |
| 10P GAIN WILD-TYPE | 52 | 49 | 37 | 33 | 37 |
Figure S77. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00169 (Fisher's exact test), Q value = 0.0055
Table S78. Gene #19: '10p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 10P GAIN MUTATED | 40 | 18 | 37 |
| 10P GAIN WILD-TYPE | 203 | 64 | 72 |
Figure S78. Get High-res Image Gene #19: '10p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S79. Gene #20: '10q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 10Q GAIN MUTATED | 20 | 7 | 6 | 33 | 4 |
| 10Q GAIN WILD-TYPE | 103 | 180 | 30 | 43 | 15 |
Figure S79. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0401 (Fisher's exact test), Q value = 0.082
Table S80. Gene #20: '10q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 10Q GAIN MUTATED | 27 | 19 | 2 | 13 |
| 10Q GAIN WILD-TYPE | 97 | 102 | 40 | 93 |
Figure S80. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0167 (Fisher's exact test), Q value = 0.04
Table S81. Gene #20: '10q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 10Q GAIN MUTATED | 9 | 9 | 5 | 3 | 20 |
| 10Q GAIN WILD-TYPE | 53 | 53 | 39 | 37 | 44 |
Figure S81. Get High-res Image Gene #20: '10q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S82. Gene #21: '11p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 11P GAIN MUTATED | 35 | 10 | 3 | 13 | 3 |
| 11P GAIN WILD-TYPE | 88 | 177 | 33 | 63 | 16 |
Figure S82. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.002
Table S83. Gene #21: '11p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 11P GAIN MUTATED | 32 | 10 | 6 | 10 |
| 11P GAIN WILD-TYPE | 92 | 111 | 36 | 96 |
Figure S83. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00978 (Fisher's exact test), Q value = 0.025
Table S84. Gene #21: '11p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 11P GAIN MUTATED | 18 | 3 | 5 |
| 11P GAIN WILD-TYPE | 92 | 54 | 100 |
Figure S84. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S85. Gene #21: '11p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 11P GAIN MUTATED | 20 | 8 | 33 |
| 11P GAIN WILD-TYPE | 152 | 122 | 99 |
Figure S85. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00035
Table S86. Gene #21: '11p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 11P GAIN MUTATED | 27 | 5 | 29 |
| 11P GAIN WILD-TYPE | 216 | 77 | 80 |
Figure S86. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0474 (Fisher's exact test), Q value = 0.094
Table S87. Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 11P GAIN MUTATED | 17 | 10 | 4 | 7 | 5 | 4 |
| 11P GAIN WILD-TYPE | 56 | 47 | 55 | 53 | 28 | 55 |
Figure S87. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0462 (Fisher's exact test), Q value = 0.092
Table S88. Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 11P GAIN MUTATED | 12 | 4 | 2 | 10 | 3 | 16 |
| 11P GAIN WILD-TYPE | 72 | 53 | 33 | 66 | 25 | 45 |
Figure S88. Get High-res Image Gene #21: '11p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S89. Gene #22: '11q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 11Q GAIN MUTATED | 39 | 10 | 2 | 18 | 5 |
| 11Q GAIN WILD-TYPE | 84 | 177 | 34 | 58 | 14 |
Figure S89. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00071
Table S90. Gene #22: '11q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 11Q GAIN MUTATED | 36 | 14 | 6 | 9 |
| 11Q GAIN WILD-TYPE | 88 | 107 | 36 | 97 |
Figure S90. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0362 (Fisher's exact test), Q value = 0.075
Table S91. Gene #22: '11q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 11Q GAIN MUTATED | 2 | 23 | 16 | 10 | 7 |
| 11Q GAIN WILD-TYPE | 28 | 69 | 66 | 83 | 52 |
Figure S91. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00128 (Fisher's exact test), Q value = 0.0044
Table S92. Gene #22: '11q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 11Q GAIN MUTATED | 23 | 2 | 8 |
| 11Q GAIN WILD-TYPE | 87 | 55 | 97 |
Figure S92. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S93. Gene #22: '11q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 11Q GAIN MUTATED | 25 | 7 | 39 |
| 11Q GAIN WILD-TYPE | 147 | 123 | 93 |
Figure S93. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S94. Gene #22: '11q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 11Q GAIN MUTATED | 36 | 4 | 31 |
| 11Q GAIN WILD-TYPE | 207 | 78 | 78 |
Figure S94. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00371 (Fisher's exact test), Q value = 0.011
Table S95. Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 11Q GAIN MUTATED | 19 | 12 | 4 | 9 | 7 | 3 |
| 11Q GAIN WILD-TYPE | 54 | 45 | 55 | 51 | 26 | 56 |
Figure S95. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00634 (Fisher's exact test), Q value = 0.017
Table S96. Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 11Q GAIN MUTATED | 17 | 3 | 2 | 12 | 3 | 17 |
| 11Q GAIN WILD-TYPE | 67 | 54 | 33 | 64 | 25 | 44 |
Figure S96. Get High-res Image Gene #22: '11q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00018 (Fisher's exact test), Q value = 0.00078
Table S97. Gene #23: '12p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 12P GAIN MUTATED | 27 | 21 | 11 | 27 | 4 |
| 12P GAIN WILD-TYPE | 96 | 166 | 25 | 49 | 15 |
Figure S97. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0154 (Fisher's exact test), Q value = 0.037
Table S98. Gene #23: '12p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 12P GAIN MUTATED | 27 | 4 | 22 |
| 12P GAIN WILD-TYPE | 83 | 53 | 83 |
Figure S98. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0107 (Fisher's exact test), Q value = 0.028
Table S99. Gene #23: '12p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 12P GAIN MUTATED | 33 | 18 | 38 |
| 12P GAIN WILD-TYPE | 139 | 112 | 94 |
Figure S99. Get High-res Image Gene #23: '12p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00363 (Fisher's exact test), Q value = 0.011
Table S100. Gene #24: '12q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 12Q GAIN MUTATED | 20 | 21 | 9 | 23 | 4 |
| 12Q GAIN WILD-TYPE | 103 | 166 | 27 | 53 | 15 |
Figure S100. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00212 (Fisher's exact test), Q value = 0.0067
Table S101. Gene #24: '12q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 12Q GAIN MUTATED | 7 | 8 | 16 | 7 | 16 |
| 12Q GAIN WILD-TYPE | 23 | 84 | 66 | 86 | 43 |
Figure S101. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0495 (Fisher's exact test), Q value = 0.097
Table S102. Gene #24: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 12Q GAIN MUTATED | 27 | 17 | 32 |
| 12Q GAIN WILD-TYPE | 145 | 113 | 100 |
Figure S102. Get High-res Image Gene #24: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S103. Gene #25: '13q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 13Q GAIN MUTATED | 71 | 36 | 23 | 17 | 7 |
| 13Q GAIN WILD-TYPE | 52 | 151 | 13 | 59 | 12 |
Figure S103. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00035
Table S104. Gene #25: '13q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 13Q GAIN MUTATED | 63 | 36 | 8 | 29 |
| 13Q GAIN WILD-TYPE | 61 | 85 | 34 | 77 |
Figure S104. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0146 (Fisher's exact test), Q value = 0.036
Table S105. Gene #25: '13q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 13Q GAIN MUTATED | 17 | 17 | 9 | 21 | 25 |
| 13Q GAIN WILD-TYPE | 45 | 45 | 35 | 19 | 39 |
Figure S105. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0013 (Fisher's exact test), Q value = 0.0045
Table S106. Gene #25: '13q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 13Q GAIN MUTATED | 51 | 36 | 62 |
| 13Q GAIN WILD-TYPE | 121 | 94 | 70 |
Figure S106. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00072 (Fisher's exact test), Q value = 0.0027
Table S107. Gene #25: '13q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 13Q GAIN MUTATED | 71 | 24 | 54 |
| 13Q GAIN WILD-TYPE | 172 | 58 | 55 |
Figure S107. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0152 (Fisher's exact test), Q value = 0.037
Table S108. Gene #25: '13q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 13Q GAIN MUTATED | 34 | 17 | 18 | 16 | 16 | 13 |
| 13Q GAIN WILD-TYPE | 39 | 40 | 41 | 44 | 17 | 46 |
Figure S108. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0204 (Fisher's exact test), Q value = 0.047
Table S109. Gene #25: '13q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 13Q GAIN MUTATED | 27 | 15 | 9 | 25 | 6 | 32 |
| 13Q GAIN WILD-TYPE | 57 | 42 | 26 | 51 | 22 | 29 |
Figure S109. Get High-res Image Gene #25: '13q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S110. Gene #26: '14q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 14Q GAIN MUTATED | 19 | 5 | 4 | 1 | 0 |
| 14Q GAIN WILD-TYPE | 104 | 182 | 32 | 75 | 19 |
Figure S110. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00159 (Fisher's exact test), Q value = 0.0053
Table S111. Gene #26: '14q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 14Q GAIN MUTATED | 4 | 8 | 17 |
| 14Q GAIN WILD-TYPE | 168 | 122 | 115 |
Figure S111. Get High-res Image Gene #26: '14q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S112. Gene #27: '15q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 15Q GAIN MUTATED | 16 | 5 | 3 | 15 | 0 |
| 15Q GAIN WILD-TYPE | 107 | 182 | 33 | 61 | 19 |
Figure S112. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00035
Table S113. Gene #27: '15q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 15Q GAIN MUTATED | 24 | 5 | 1 | 5 |
| 15Q GAIN WILD-TYPE | 100 | 116 | 41 | 101 |
Figure S113. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0499 (Fisher's exact test), Q value = 0.097
Table S114. Gene #27: '15q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 15Q GAIN MUTATED | 5 | 1 | 1 | 5 | 8 |
| 15Q GAIN WILD-TYPE | 57 | 61 | 43 | 35 | 56 |
Figure S114. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00306 (Fisher's exact test), Q value = 0.0092
Table S115. Gene #27: '15q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 15Q GAIN MUTATED | 16 | 3 | 18 |
| 15Q GAIN WILD-TYPE | 227 | 79 | 91 |
Figure S115. Get High-res Image Gene #27: '15q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00113 (Fisher's exact test), Q value = 0.004
Table S116. Gene #28: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 16P GAIN MUTATED | 23 | 12 | 4 | 17 | 3 |
| 16P GAIN WILD-TYPE | 100 | 175 | 32 | 59 | 16 |
Figure S116. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0229 (Fisher's exact test), Q value = 0.051
Table S117. Gene #28: '16p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 16P GAIN MUTATED | 27 | 4 | 5 | 10 |
| 16P GAIN WILD-TYPE | 113 | 54 | 73 | 70 |
Figure S117. Get High-res Image Gene #28: '16p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00268 (Fisher's exact test), Q value = 0.0082
Table S118. Gene #29: '16q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 16Q GAIN MUTATED | 19 | 9 | 4 | 14 | 1 |
| 16Q GAIN WILD-TYPE | 104 | 178 | 32 | 62 | 18 |
Figure S118. Get High-res Image Gene #29: '16q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00113 (Fisher's exact test), Q value = 0.004
Table S119. Gene #30: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 17P GAIN MUTATED | 17 | 5 | 3 | 2 | 2 |
| 17P GAIN WILD-TYPE | 106 | 182 | 33 | 74 | 17 |
Figure S119. Get High-res Image Gene #30: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S120. Gene #31: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 17Q GAIN MUTATED | 30 | 10 | 6 | 12 | 4 |
| 17Q GAIN WILD-TYPE | 93 | 177 | 30 | 64 | 15 |
Figure S120. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.048 (Fisher's exact test), Q value = 0.095
Table S121. Gene #31: '17q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 17Q GAIN MUTATED | 23 | 17 | 9 | 8 |
| 17Q GAIN WILD-TYPE | 101 | 104 | 33 | 98 |
Figure S121. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0419 (Fisher's exact test), Q value = 0.085
Table S122. Gene #31: '17q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 17Q GAIN MUTATED | 19 | 3 | 9 |
| 17Q GAIN WILD-TYPE | 91 | 54 | 96 |
Figure S122. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0162 (Fisher's exact test), Q value = 0.039
Table S123. Gene #31: '17q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 17Q GAIN MUTATED | 21 | 12 | 28 |
| 17Q GAIN WILD-TYPE | 151 | 118 | 104 |
Figure S123. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0259 (Fisher's exact test), Q value = 0.057
Table S124. Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 17Q GAIN MUTATED | 10 | 2 | 4 | 17 | 2 | 11 |
| 17Q GAIN WILD-TYPE | 74 | 55 | 31 | 59 | 26 | 50 |
Figure S124. Get High-res Image Gene #31: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S125. Gene #32: '18p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 18P GAIN MUTATED | 42 | 14 | 7 | 17 | 4 |
| 18P GAIN WILD-TYPE | 81 | 173 | 29 | 59 | 15 |
Figure S125. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S126. Gene #32: '18p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 18P GAIN MUTATED | 45 | 20 | 0 | 11 |
| 18P GAIN WILD-TYPE | 79 | 101 | 42 | 95 |
Figure S126. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0013
Table S127. Gene #32: '18p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 18P GAIN MUTATED | 40 | 7 | 8 | 8 |
| 18P GAIN WILD-TYPE | 100 | 51 | 70 | 72 |
Figure S127. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00951 (Fisher's exact test), Q value = 0.025
Table S128. Gene #32: '18p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 18P GAIN MUTATED | 5 | 6 | 9 | 6 | 19 |
| 18P GAIN WILD-TYPE | 57 | 56 | 35 | 34 | 45 |
Figure S128. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S129. Gene #32: '18p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 18P GAIN MUTATED | 24 | 16 | 44 |
| 18P GAIN WILD-TYPE | 148 | 114 | 88 |
Figure S129. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S130. Gene #32: '18p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 18P GAIN MUTATED | 37 | 9 | 38 |
| 18P GAIN WILD-TYPE | 206 | 73 | 71 |
Figure S130. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00414 (Fisher's exact test), Q value = 0.012
Table S131. Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 18P GAIN MUTATED | 27 | 8 | 11 | 10 | 3 | 8 |
| 18P GAIN WILD-TYPE | 46 | 49 | 48 | 50 | 30 | 51 |
Figure S131. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0014
Table S132. Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 18P GAIN MUTATED | 24 | 4 | 3 | 11 | 4 | 21 |
| 18P GAIN WILD-TYPE | 60 | 53 | 32 | 65 | 24 | 40 |
Figure S132. Get High-res Image Gene #32: '18p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00615 (Fisher's exact test), Q value = 0.017
Table S133. Gene #33: '18q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 18Q GAIN MUTATED | 22 | 12 | 3 | 13 | 4 |
| 18Q GAIN WILD-TYPE | 101 | 175 | 33 | 63 | 15 |
Figure S133. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00283 (Fisher's exact test), Q value = 0.0086
Table S134. Gene #33: '18q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 18Q GAIN MUTATED | 24 | 13 | 0 | 11 |
| 18Q GAIN WILD-TYPE | 100 | 108 | 42 | 95 |
Figure S134. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0274 (Fisher's exact test), Q value = 0.059
Table S135. Gene #33: '18q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 18Q GAIN MUTATED | 15 | 14 | 25 |
| 18Q GAIN WILD-TYPE | 157 | 116 | 107 |
Figure S135. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0266 (Fisher's exact test), Q value = 0.058
Table S136. Gene #33: '18q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 18Q GAIN MUTATED | 24 | 8 | 22 |
| 18Q GAIN WILD-TYPE | 219 | 74 | 87 |
Figure S136. Get High-res Image Gene #33: '18q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S137. Gene #34: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 19P GAIN MUTATED | 22 | 9 | 8 | 15 | 0 |
| 19P GAIN WILD-TYPE | 101 | 178 | 28 | 61 | 19 |
Figure S137. Get High-res Image Gene #34: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S138. Gene #35: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 19Q GAIN MUTATED | 36 | 13 | 9 | 20 | 0 |
| 19Q GAIN WILD-TYPE | 87 | 174 | 27 | 56 | 19 |
Figure S138. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.017 (Fisher's exact test), Q value = 0.04
Table S139. Gene #35: '19q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 19Q GAIN MUTATED | 6 | 14 | 21 | 7 | 12 |
| 19Q GAIN WILD-TYPE | 24 | 78 | 61 | 86 | 47 |
Figure S139. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0337 (Fisher's exact test), Q value = 0.07
Table S140. Gene #35: '19q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 19Q GAIN MUTATED | 33 | 9 | 11 | 7 |
| 19Q GAIN WILD-TYPE | 107 | 49 | 67 | 73 |
Figure S140. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.014 (Fisher's exact test), Q value = 0.035
Table S141. Gene #35: '19q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 19Q GAIN MUTATED | 10 | 7 | 6 | 4 | 21 |
| 19Q GAIN WILD-TYPE | 52 | 55 | 38 | 36 | 43 |
Figure S141. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00669 (Fisher's exact test), Q value = 0.018
Table S142. Gene #35: '19q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 19Q GAIN MUTATED | 29 | 5 | 14 |
| 19Q GAIN WILD-TYPE | 81 | 52 | 91 |
Figure S142. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0251 (Fisher's exact test), Q value = 0.055
Table S143. Gene #35: '19q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 19Q GAIN MUTATED | 30 | 15 | 32 |
| 19Q GAIN WILD-TYPE | 142 | 115 | 100 |
Figure S143. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0171 (Fisher's exact test), Q value = 0.04
Table S144. Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 19Q GAIN MUTATED | 22 | 6 | 6 | 10 | 8 | 7 |
| 19Q GAIN WILD-TYPE | 51 | 51 | 53 | 50 | 25 | 52 |
Figure S144. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0452 (Fisher's exact test), Q value = 0.091
Table S145. Gene #35: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 19Q GAIN MUTATED | 11 | 6 | 4 | 13 | 6 | 19 |
| 19Q GAIN WILD-TYPE | 73 | 51 | 31 | 63 | 22 | 42 |
Figure S145. Get High-res Image Gene #35: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S146. Gene #36: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 20P GAIN MUTATED | 93 | 58 | 25 | 52 | 15 |
| 20P GAIN WILD-TYPE | 30 | 129 | 11 | 24 | 4 |
Figure S146. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S147. Gene #36: '20p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 20P GAIN MUTATED | 92 | 53 | 29 | 42 |
| 20P GAIN WILD-TYPE | 32 | 68 | 13 | 64 |
Figure S147. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0145 (Fisher's exact test), Q value = 0.036
Table S148. Gene #36: '20p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 20P GAIN MUTATED | 88 | 27 | 45 | 34 |
| 20P GAIN WILD-TYPE | 52 | 31 | 33 | 46 |
Figure S148. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00095 (Fisher's exact test), Q value = 0.0035
Table S149. Gene #36: '20p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 20P GAIN MUTATED | 25 | 27 | 20 | 25 | 46 |
| 20P GAIN WILD-TYPE | 37 | 35 | 24 | 15 | 18 |
Figure S149. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00038
Table S150. Gene #36: '20p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 20P GAIN MUTATED | 75 | 23 | 45 |
| 20P GAIN WILD-TYPE | 35 | 34 | 60 |
Figure S150. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S151. Gene #36: '20p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 20P GAIN MUTATED | 84 | 61 | 94 |
| 20P GAIN WILD-TYPE | 88 | 69 | 38 |
Figure S151. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S152. Gene #36: '20p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 20P GAIN MUTATED | 119 | 37 | 83 |
| 20P GAIN WILD-TYPE | 124 | 45 | 26 |
Figure S152. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00038
Table S153. Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 20P GAIN MUTATED | 57 | 24 | 28 | 27 | 20 | 26 |
| 20P GAIN WILD-TYPE | 16 | 33 | 31 | 33 | 13 | 33 |
Figure S153. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00035 (Fisher's exact test), Q value = 0.0014
Table S154. Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 20P GAIN MUTATED | 45 | 25 | 16 | 33 | 15 | 48 |
| 20P GAIN WILD-TYPE | 39 | 32 | 19 | 43 | 13 | 13 |
Figure S154. Get High-res Image Gene #36: '20p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S155. Gene #37: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 20Q GAIN MUTATED | 108 | 66 | 31 | 59 | 15 |
| 20Q GAIN WILD-TYPE | 15 | 121 | 5 | 17 | 4 |
Figure S155. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S156. Gene #37: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 20Q GAIN MUTATED | 112 | 58 | 31 | 50 |
| 20Q GAIN WILD-TYPE | 12 | 63 | 11 | 56 |
Figure S156. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00156 (Fisher's exact test), Q value = 0.0052
Table S157. Gene #37: '20q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 20Q GAIN MUTATED | 102 | 28 | 51 | 42 |
| 20Q GAIN WILD-TYPE | 38 | 30 | 27 | 38 |
Figure S157. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S158. Gene #37: '20q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 20Q GAIN MUTATED | 28 | 31 | 25 | 26 | 58 |
| 20Q GAIN WILD-TYPE | 34 | 31 | 19 | 14 | 6 |
Figure S158. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S159. Gene #37: '20q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 20Q GAIN MUTATED | 89 | 25 | 54 |
| 20Q GAIN WILD-TYPE | 21 | 32 | 51 |
Figure S159. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S160. Gene #37: '20q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 20Q GAIN MUTATED | 94 | 71 | 109 |
| 20Q GAIN WILD-TYPE | 78 | 59 | 23 |
Figure S160. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S161. Gene #37: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 20Q GAIN MUTATED | 135 | 41 | 98 |
| 20Q GAIN WILD-TYPE | 108 | 41 | 11 |
Figure S161. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00038
Table S162. Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 20Q GAIN MUTATED | 61 | 28 | 34 | 36 | 25 | 30 |
| 20Q GAIN WILD-TYPE | 12 | 29 | 25 | 24 | 8 | 29 |
Figure S162. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S163. Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 20Q GAIN MUTATED | 55 | 27 | 18 | 42 | 16 | 56 |
| 20Q GAIN WILD-TYPE | 29 | 30 | 17 | 34 | 12 | 5 |
Figure S163. Get High-res Image Gene #37: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00059
Table S164. Gene #38: '21q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 21Q GAIN MUTATED | 14 | 1 | 1 | 5 | 0 |
| 21Q GAIN WILD-TYPE | 109 | 186 | 35 | 71 | 19 |
Figure S164. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00144 (Fisher's exact test), Q value = 0.0049
Table S165. Gene #38: '21q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 21Q GAIN MUTATED | 14 | 5 | 0 | 1 |
| 21Q GAIN WILD-TYPE | 110 | 116 | 42 | 105 |
Figure S165. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0172 (Fisher's exact test), Q value = 0.04
Table S166. Gene #38: '21q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 21Q GAIN MUTATED | 1 | 1 | 1 | 4 | 8 |
| 21Q GAIN WILD-TYPE | 61 | 61 | 43 | 36 | 56 |
Figure S166. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0177 (Fisher's exact test), Q value = 0.041
Table S167. Gene #38: '21q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 21Q GAIN MUTATED | 7 | 2 | 12 |
| 21Q GAIN WILD-TYPE | 165 | 128 | 120 |
Figure S167. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.00078
Table S168. Gene #38: '21q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 21Q GAIN MUTATED | 8 | 0 | 13 |
| 21Q GAIN WILD-TYPE | 235 | 82 | 96 |
Figure S168. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00535 (Fisher's exact test), Q value = 0.015
Table S169. Gene #38: '21q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 21Q GAIN MUTATED | 6 | 0 | 1 | 2 | 0 | 9 |
| 21Q GAIN WILD-TYPE | 78 | 57 | 34 | 74 | 28 | 52 |
Figure S169. Get High-res Image Gene #38: '21q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00227 (Fisher's exact test), Q value = 0.007
Table S170. Gene #39: '22q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 22Q GAIN MUTATED | 17 | 5 | 4 | 6 | 0 |
| 22Q GAIN WILD-TYPE | 106 | 182 | 32 | 70 | 19 |
Figure S170. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0212 (Fisher's exact test), Q value = 0.048
Table S171. Gene #39: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 22Q GAIN MUTATED | 8 | 1 | 4 | 10 | 0 | 4 |
| 22Q GAIN WILD-TYPE | 65 | 56 | 55 | 50 | 33 | 55 |
Figure S171. Get High-res Image Gene #39: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S172. Gene #40: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| XP GAIN MUTATED | 20 | 6 | 10 | 7 | 5 |
| XP GAIN WILD-TYPE | 103 | 181 | 26 | 69 | 14 |
Figure S172. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00105 (Fisher's exact test), Q value = 0.0038
Table S173. Gene #40: 'xp gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| XP GAIN MUTATED | 22 | 14 | 2 | 3 |
| XP GAIN WILD-TYPE | 102 | 107 | 40 | 103 |
Figure S173. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0148 (Fisher's exact test), Q value = 0.036
Table S174. Gene #40: 'xp gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| XP GAIN MUTATED | 2 | 6 | 7 | 7 | 14 |
| XP GAIN WILD-TYPE | 60 | 56 | 37 | 33 | 50 |
Figure S174. Get High-res Image Gene #40: 'xp gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S175. Gene #41: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| XQ GAIN MUTATED | 27 | 9 | 11 | 5 | 4 |
| XQ GAIN WILD-TYPE | 96 | 178 | 25 | 71 | 15 |
Figure S175. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0267 (Fisher's exact test), Q value = 0.058
Table S176. Gene #41: 'xq gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| XQ GAIN MUTATED | 21 | 19 | 2 | 7 |
| XQ GAIN WILD-TYPE | 103 | 102 | 40 | 99 |
Figure S176. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00732 (Fisher's exact test), Q value = 0.02
Table S177. Gene #41: 'xq gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| XQ GAIN MUTATED | 2 | 7 | 7 | 10 | 13 |
| XQ GAIN WILD-TYPE | 60 | 55 | 37 | 30 | 51 |
Figure S177. Get High-res Image Gene #41: 'xq gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S178. Gene #42: '1p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 1P LOSS MUTATED | 38 | 2 | 3 | 15 | 1 |
| 1P LOSS WILD-TYPE | 85 | 185 | 33 | 61 | 18 |
Figure S178. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S179. Gene #42: '1p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 1P LOSS MUTATED | 34 | 12 | 2 | 6 |
| 1P LOSS WILD-TYPE | 90 | 109 | 40 | 100 |
Figure S179. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0125 (Fisher's exact test), Q value = 0.032
Table S180. Gene #42: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 1P LOSS MUTATED | 19 | 11 | 27 |
| 1P LOSS WILD-TYPE | 153 | 119 | 105 |
Figure S180. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0033 (Fisher's exact test), Q value = 0.0099
Table S181. Gene #42: '1p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 1P LOSS MUTATED | 25 | 7 | 25 |
| 1P LOSS WILD-TYPE | 218 | 75 | 84 |
Figure S181. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.019 (Fisher's exact test), Q value = 0.044
Table S182. Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 1P LOSS MUTATED | 18 | 4 | 10 | 4 | 4 | 5 |
| 1P LOSS WILD-TYPE | 55 | 53 | 49 | 56 | 29 | 54 |
Figure S182. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00583 (Fisher's exact test), Q value = 0.016
Table S183. Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 1P LOSS MUTATED | 10 | 2 | 5 | 9 | 2 | 17 |
| 1P LOSS WILD-TYPE | 74 | 55 | 30 | 67 | 26 | 44 |
Figure S183. Get High-res Image Gene #42: '1p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S184. Gene #43: '1q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 1Q LOSS MUTATED | 16 | 1 | 1 | 9 | 1 |
| 1Q LOSS WILD-TYPE | 107 | 186 | 35 | 67 | 18 |
Figure S184. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S185. Gene #43: '1q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 1Q LOSS MUTATED | 20 | 4 | 1 | 2 |
| 1Q LOSS WILD-TYPE | 104 | 117 | 41 | 104 |
Figure S185. Get High-res Image Gene #43: '1q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S186. Gene #44: '2p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 2P LOSS MUTATED | 15 | 1 | 2 | 8 | 0 |
| 2P LOSS WILD-TYPE | 108 | 186 | 34 | 68 | 19 |
Figure S186. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00023 (Fisher's exact test), Q value = 0.00098
Table S187. Gene #44: '2p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 2P LOSS MUTATED | 18 | 4 | 0 | 3 |
| 2P LOSS WILD-TYPE | 106 | 117 | 42 | 103 |
Figure S187. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0212 (Fisher's exact test), Q value = 0.048
Table S188. Gene #44: '2p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 2P LOSS MUTATED | 0 | 1 | 3 | 4 | 6 |
| 2P LOSS WILD-TYPE | 62 | 61 | 41 | 36 | 58 |
Figure S188. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0415 (Fisher's exact test), Q value = 0.084
Table S189. Gene #44: '2p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 2P LOSS MUTATED | 7 | 5 | 14 |
| 2P LOSS WILD-TYPE | 165 | 125 | 118 |
Figure S189. Get High-res Image Gene #44: '2p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S190. Gene #45: '2q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 2Q LOSS MUTATED | 20 | 1 | 3 | 9 | 0 |
| 2Q LOSS WILD-TYPE | 103 | 186 | 33 | 67 | 19 |
Figure S190. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.002
Table S191. Gene #45: '2q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 2Q LOSS MUTATED | 20 | 6 | 0 | 4 |
| 2Q LOSS WILD-TYPE | 104 | 115 | 42 | 102 |
Figure S191. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.015 (Fisher's exact test), Q value = 0.037
Table S192. Gene #45: '2q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 2Q LOSS MUTATED | 0 | 1 | 4 | 4 | 6 |
| 2Q LOSS WILD-TYPE | 62 | 61 | 40 | 36 | 58 |
Figure S192. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00349 (Fisher's exact test), Q value = 0.01
Table S193. Gene #45: '2q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 2Q LOSS MUTATED | 8 | 6 | 19 |
| 2Q LOSS WILD-TYPE | 164 | 124 | 113 |
Figure S193. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0241 (Fisher's exact test), Q value = 0.053
Table S194. Gene #45: '2q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 2Q LOSS MUTATED | 15 | 3 | 15 |
| 2Q LOSS WILD-TYPE | 228 | 79 | 94 |
Figure S194. Get High-res Image Gene #45: '2q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S195. Gene #46: '3p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 3P LOSS MUTATED | 45 | 10 | 8 | 24 | 4 |
| 3P LOSS WILD-TYPE | 78 | 177 | 28 | 52 | 15 |
Figure S195. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S196. Gene #46: '3p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 3P LOSS MUTATED | 43 | 26 | 4 | 11 |
| 3P LOSS WILD-TYPE | 81 | 95 | 38 | 95 |
Figure S196. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0107 (Fisher's exact test), Q value = 0.028
Table S197. Gene #46: '3p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 3P LOSS MUTATED | 6 | 7 | 6 | 9 | 20 |
| 3P LOSS WILD-TYPE | 56 | 55 | 38 | 31 | 44 |
Figure S197. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00032 (Fisher's exact test), Q value = 0.0013
Table S198. Gene #46: '3p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 3P LOSS MUTATED | 26 | 20 | 43 |
| 3P LOSS WILD-TYPE | 146 | 110 | 89 |
Figure S198. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00114 (Fisher's exact test), Q value = 0.004
Table S199. Gene #46: '3p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 3P LOSS MUTATED | 42 | 11 | 36 |
| 3P LOSS WILD-TYPE | 201 | 71 | 73 |
Figure S199. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 7e-04 (Fisher's exact test), Q value = 0.0026
Table S200. Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 3P LOSS MUTATED | 14 | 5 | 3 | 21 | 3 | 22 |
| 3P LOSS WILD-TYPE | 70 | 52 | 32 | 55 | 25 | 39 |
Figure S200. Get High-res Image Gene #46: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S201. Gene #47: '3q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 3Q LOSS MUTATED | 32 | 3 | 7 | 11 | 1 |
| 3Q LOSS WILD-TYPE | 91 | 184 | 29 | 65 | 18 |
Figure S201. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S202. Gene #47: '3q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 3Q LOSS MUTATED | 29 | 15 | 1 | 5 |
| 3Q LOSS WILD-TYPE | 95 | 106 | 41 | 101 |
Figure S202. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S203. Gene #47: '3q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 3Q LOSS MUTATED | 2 | 3 | 0 | 7 | 16 |
| 3Q LOSS WILD-TYPE | 60 | 59 | 44 | 33 | 48 |
Figure S203. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00828 (Fisher's exact test), Q value = 0.022
Table S204. Gene #47: '3q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 3Q LOSS MUTATED | 19 | 2 | 7 |
| 3Q LOSS WILD-TYPE | 91 | 55 | 98 |
Figure S204. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00513 (Fisher's exact test), Q value = 0.015
Table S205. Gene #47: '3q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 3Q LOSS MUTATED | 13 | 13 | 26 |
| 3Q LOSS WILD-TYPE | 159 | 117 | 106 |
Figure S205. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00572 (Fisher's exact test), Q value = 0.016
Table S206. Gene #47: '3q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 3Q LOSS MUTATED | 22 | 7 | 23 |
| 3Q LOSS WILD-TYPE | 221 | 75 | 86 |
Figure S206. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 7e-04 (Fisher's exact test), Q value = 0.0026
Table S207. Gene #47: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 3Q LOSS MUTATED | 5 | 3 | 1 | 13 | 2 | 16 |
| 3Q LOSS WILD-TYPE | 79 | 54 | 34 | 63 | 26 | 45 |
Figure S207. Get High-res Image Gene #47: '3q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S208. Gene #48: '4p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 4P LOSS MUTATED | 76 | 27 | 12 | 47 | 5 |
| 4P LOSS WILD-TYPE | 47 | 160 | 24 | 29 | 14 |
Figure S208. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S209. Gene #48: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 4P LOSS MUTATED | 73 | 38 | 4 | 33 |
| 4P LOSS WILD-TYPE | 51 | 83 | 38 | 73 |
Figure S209. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00191 (Fisher's exact test), Q value = 0.0061
Table S210. Gene #48: '4p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 4P LOSS MUTATED | 12 | 22 | 14 | 11 | 34 |
| 4P LOSS WILD-TYPE | 50 | 40 | 30 | 29 | 30 |
Figure S210. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S211. Gene #48: '4p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 4P LOSS MUTATED | 51 | 41 | 74 |
| 4P LOSS WILD-TYPE | 121 | 89 | 58 |
Figure S211. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S212. Gene #48: '4p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 4P LOSS MUTATED | 70 | 26 | 70 |
| 4P LOSS WILD-TYPE | 173 | 56 | 39 |
Figure S212. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00117 (Fisher's exact test), Q value = 0.0041
Table S213. Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 4P LOSS MUTATED | 43 | 21 | 14 | 18 | 13 | 22 |
| 4P LOSS WILD-TYPE | 30 | 36 | 45 | 42 | 20 | 37 |
Figure S213. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S214. Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 4P LOSS MUTATED | 33 | 19 | 4 | 24 | 7 | 44 |
| 4P LOSS WILD-TYPE | 51 | 38 | 31 | 52 | 21 | 17 |
Figure S214. Get High-res Image Gene #48: '4p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S215. Gene #49: '4q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 4Q LOSS MUTATED | 72 | 26 | 10 | 51 | 5 |
| 4Q LOSS WILD-TYPE | 51 | 161 | 26 | 25 | 14 |
Figure S215. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S216. Gene #49: '4q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 4Q LOSS MUTATED | 71 | 39 | 4 | 34 |
| 4Q LOSS WILD-TYPE | 53 | 82 | 38 | 72 |
Figure S216. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.015 (Fisher's exact test), Q value = 0.037
Table S217. Gene #49: '4q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 4Q LOSS MUTATED | 12 | 22 | 15 | 12 | 31 |
| 4Q LOSS WILD-TYPE | 50 | 40 | 29 | 28 | 33 |
Figure S217. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00038
Table S218. Gene #49: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 4Q LOSS MUTATED | 50 | 43 | 69 |
| 4Q LOSS WILD-TYPE | 122 | 87 | 63 |
Figure S218. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S219. Gene #49: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 4Q LOSS MUTATED | 69 | 25 | 68 |
| 4Q LOSS WILD-TYPE | 174 | 57 | 41 |
Figure S219. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0185 (Fisher's exact test), Q value = 0.043
Table S220. Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 4Q LOSS MUTATED | 41 | 20 | 16 | 20 | 12 | 22 |
| 4Q LOSS WILD-TYPE | 32 | 37 | 43 | 40 | 21 | 37 |
Figure S220. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S221. Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 4Q LOSS MUTATED | 31 | 19 | 5 | 24 | 7 | 45 |
| 4Q LOSS WILD-TYPE | 53 | 38 | 30 | 52 | 21 | 16 |
Figure S221. Get High-res Image Gene #49: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S222. Gene #50: '5p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 5P LOSS MUTATED | 28 | 5 | 4 | 19 | 4 |
| 5P LOSS WILD-TYPE | 95 | 182 | 32 | 57 | 15 |
Figure S222. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S223. Gene #50: '5p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 5P LOSS MUTATED | 31 | 17 | 1 | 6 |
| 5P LOSS WILD-TYPE | 93 | 104 | 41 | 100 |
Figure S223. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00686 (Fisher's exact test), Q value = 0.019
Table S224. Gene #50: '5p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 5P LOSS MUTATED | 6 | 2 | 2 | 6 | 14 |
| 5P LOSS WILD-TYPE | 56 | 60 | 42 | 34 | 50 |
Figure S224. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S225. Gene #50: '5p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 5P LOSS MUTATED | 14 | 11 | 33 |
| 5P LOSS WILD-TYPE | 158 | 119 | 99 |
Figure S225. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S226. Gene #50: '5p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 5P LOSS MUTATED | 23 | 6 | 29 |
| 5P LOSS WILD-TYPE | 220 | 76 | 80 |
Figure S226. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0237 (Fisher's exact test), Q value = 0.052
Table S227. Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 5P LOSS MUTATED | 20 | 8 | 6 | 5 | 5 | 5 |
| 5P LOSS WILD-TYPE | 53 | 49 | 53 | 55 | 28 | 54 |
Figure S227. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00149 (Fisher's exact test), Q value = 0.005
Table S228. Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 5P LOSS MUTATED | 9 | 4 | 2 | 10 | 4 | 20 |
| 5P LOSS WILD-TYPE | 75 | 53 | 33 | 66 | 24 | 41 |
Figure S228. Get High-res Image Gene #50: '5p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S229. Gene #51: '5q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 5Q LOSS MUTATED | 58 | 6 | 9 | 27 | 6 |
| 5Q LOSS WILD-TYPE | 65 | 181 | 27 | 49 | 13 |
Figure S229. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S230. Gene #51: '5q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 5Q LOSS MUTATED | 61 | 24 | 3 | 11 |
| 5Q LOSS WILD-TYPE | 63 | 97 | 39 | 95 |
Figure S230. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S231. Gene #51: '5q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 5Q LOSS MUTATED | 10 | 3 | 5 | 8 | 27 |
| 5Q LOSS WILD-TYPE | 52 | 59 | 39 | 32 | 37 |
Figure S231. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0207 (Fisher's exact test), Q value = 0.047
Table S232. Gene #51: '5q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 5Q LOSS MUTATED | 29 | 5 | 19 |
| 5Q LOSS WILD-TYPE | 81 | 52 | 86 |
Figure S232. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S233. Gene #51: '5q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 5Q LOSS MUTATED | 28 | 16 | 60 |
| 5Q LOSS WILD-TYPE | 144 | 114 | 72 |
Figure S233. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S234. Gene #51: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 5Q LOSS MUTATED | 41 | 9 | 54 |
| 5Q LOSS WILD-TYPE | 202 | 73 | 55 |
Figure S234. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.00071
Table S235. Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 5Q LOSS MUTATED | 36 | 13 | 11 | 11 | 8 | 10 |
| 5Q LOSS WILD-TYPE | 37 | 44 | 48 | 49 | 25 | 49 |
Figure S235. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S236. Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 5Q LOSS MUTATED | 21 | 5 | 4 | 16 | 5 | 38 |
| 5Q LOSS WILD-TYPE | 63 | 52 | 31 | 60 | 23 | 23 |
Figure S236. Get High-res Image Gene #51: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S237. Gene #52: '6p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 6P LOSS MUTATED | 17 | 7 | 5 | 20 | 3 |
| 6P LOSS WILD-TYPE | 106 | 180 | 31 | 56 | 16 |
Figure S237. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00016 (Fisher's exact test), Q value = 0.00071
Table S238. Gene #52: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 6P LOSS MUTATED | 28 | 12 | 0 | 9 |
| 6P LOSS WILD-TYPE | 96 | 109 | 42 | 97 |
Figure S238. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0154 (Fisher's exact test), Q value = 0.037
Table S239. Gene #52: '6p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 6P LOSS MUTATED | 2 | 10 | 11 | 4 | 13 |
| 6P LOSS WILD-TYPE | 28 | 82 | 71 | 89 | 46 |
Figure S239. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0451 (Fisher's exact test), Q value = 0.091
Table S240. Gene #52: '6p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 6P LOSS MUTATED | 3 | 2 | 7 | 4 | 10 |
| 6P LOSS WILD-TYPE | 59 | 60 | 37 | 36 | 54 |
Figure S240. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0192 (Fisher's exact test), Q value = 0.044
Table S241. Gene #52: '6p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 6P LOSS MUTATED | 16 | 1 | 9 |
| 6P LOSS WILD-TYPE | 94 | 56 | 96 |
Figure S241. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0143 (Fisher's exact test), Q value = 0.035
Table S242. Gene #52: '6p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 6P LOSS MUTATED | 25 | 5 | 21 |
| 6P LOSS WILD-TYPE | 218 | 77 | 88 |
Figure S242. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0266 (Fisher's exact test), Q value = 0.058
Table S243. Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 6P LOSS MUTATED | 11 | 2 | 2 | 13 | 1 | 12 |
| 6P LOSS WILD-TYPE | 73 | 55 | 33 | 63 | 27 | 49 |
Figure S243. Get High-res Image Gene #52: '6p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S244. Gene #53: '6q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 6Q LOSS MUTATED | 22 | 11 | 8 | 25 | 4 |
| 6Q LOSS WILD-TYPE | 101 | 176 | 28 | 51 | 15 |
Figure S244. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0012 (Fisher's exact test), Q value = 0.0042
Table S245. Gene #53: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 6Q LOSS MUTATED | 33 | 14 | 2 | 14 |
| 6Q LOSS WILD-TYPE | 91 | 107 | 40 | 92 |
Figure S245. Get High-res Image Gene #53: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.002
Table S246. Gene #54: '7p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 7P LOSS MUTATED | 12 | 1 | 1 | 6 | 0 |
| 7P LOSS WILD-TYPE | 111 | 186 | 35 | 70 | 19 |
Figure S246. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00166 (Fisher's exact test), Q value = 0.0054
Table S247. Gene #54: '7p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 7P LOSS MUTATED | 13 | 2 | 1 | 1 |
| 7P LOSS WILD-TYPE | 111 | 119 | 41 | 105 |
Figure S247. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0206 (Fisher's exact test), Q value = 0.047
Table S248. Gene #54: '7p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 7P LOSS MUTATED | 1 | 1 | 0 | 1 | 7 |
| 7P LOSS WILD-TYPE | 61 | 61 | 44 | 39 | 57 |
Figure S248. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00088 (Fisher's exact test), Q value = 0.0032
Table S249. Gene #54: '7p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 7P LOSS MUTATED | 3 | 3 | 14 |
| 7P LOSS WILD-TYPE | 169 | 127 | 118 |
Figure S249. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00979 (Fisher's exact test), Q value = 0.025
Table S250. Gene #54: '7p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 7P LOSS MUTATED | 6 | 3 | 11 |
| 7P LOSS WILD-TYPE | 237 | 79 | 98 |
Figure S250. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00417 (Fisher's exact test), Q value = 0.012
Table S251. Gene #54: '7p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 7P LOSS MUTATED | 9 | 1 | 1 | 1 | 2 | 0 |
| 7P LOSS WILD-TYPE | 64 | 56 | 58 | 59 | 31 | 59 |
Figure S251. Get High-res Image Gene #54: '7p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S252. Gene #55: '7q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 7Q LOSS MUTATED | 16 | 1 | 0 | 12 | 1 |
| 7Q LOSS WILD-TYPE | 107 | 186 | 36 | 64 | 18 |
Figure S252. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00189 (Fisher's exact test), Q value = 0.0061
Table S253. Gene #55: '7q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 7Q LOSS MUTATED | 16 | 9 | 0 | 2 |
| 7Q LOSS WILD-TYPE | 108 | 112 | 42 | 104 |
Figure S253. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0434 (Fisher's exact test), Q value = 0.088
Table S254. Gene #55: '7q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 7Q LOSS MUTATED | 0 | 2 | 10 | 6 | 5 |
| 7Q LOSS WILD-TYPE | 30 | 90 | 72 | 87 | 54 |
Figure S254. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0353 (Fisher's exact test), Q value = 0.073
Table S255. Gene #55: '7q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 7Q LOSS MUTATED | 1 | 3 | 2 | 2 | 10 |
| 7Q LOSS WILD-TYPE | 61 | 59 | 42 | 38 | 54 |
Figure S255. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0164 (Fisher's exact test), Q value = 0.039
Table S256. Gene #55: '7q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 7Q LOSS MUTATED | 8 | 5 | 16 |
| 7Q LOSS WILD-TYPE | 164 | 125 | 116 |
Figure S256. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0189 (Fisher's exact test), Q value = 0.044
Table S257. Gene #55: '7q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 7Q LOSS MUTATED | 11 | 4 | 14 |
| 7Q LOSS WILD-TYPE | 232 | 78 | 95 |
Figure S257. Get High-res Image Gene #55: '7q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S258. Gene #56: '8p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 8P LOSS MUTATED | 38 | 13 | 9 | 27 | 1 |
| 8P LOSS WILD-TYPE | 85 | 174 | 27 | 49 | 18 |
Figure S258. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00188 (Fisher's exact test), Q value = 0.0061
Table S259. Gene #56: '8p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 8P LOSS MUTATED | 38 | 24 | 3 | 15 |
| 8P LOSS WILD-TYPE | 86 | 97 | 39 | 91 |
Figure S259. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0489 (Fisher's exact test), Q value = 0.096
Table S260. Gene #56: '8p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 8P LOSS MUTATED | 9 | 5 | 6 | 7 | 18 |
| 8P LOSS WILD-TYPE | 53 | 57 | 38 | 33 | 46 |
Figure S260. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00103 (Fisher's exact test), Q value = 0.0037
Table S261. Gene #56: '8p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 8P LOSS MUTATED | 37 | 13 | 36 |
| 8P LOSS WILD-TYPE | 135 | 117 | 96 |
Figure S261. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00225 (Fisher's exact test), Q value = 0.007
Table S262. Gene #56: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 8P LOSS MUTATED | 52 | 6 | 28 |
| 8P LOSS WILD-TYPE | 191 | 76 | 81 |
Figure S262. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S263. Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 8P LOSS MUTATED | 20 | 2 | 0 | 25 | 6 | 17 |
| 8P LOSS WILD-TYPE | 64 | 55 | 35 | 51 | 22 | 44 |
Figure S263. Get High-res Image Gene #56: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00085 (Fisher's exact test), Q value = 0.0032
Table S264. Gene #57: '8q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 8Q LOSS MUTATED | 13 | 5 | 7 | 8 | 0 |
| 8Q LOSS WILD-TYPE | 110 | 182 | 29 | 68 | 19 |
Figure S264. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0488 (Fisher's exact test), Q value = 0.096
Table S265. Gene #57: '8q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 8Q LOSS MUTATED | 19 | 6 | 6 |
| 8Q LOSS WILD-TYPE | 153 | 124 | 126 |
Figure S265. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0225 (Fisher's exact test), Q value = 0.05
Table S266. Gene #57: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 8Q LOSS MUTATED | 8 | 2 | 0 | 12 | 2 | 2 |
| 8Q LOSS WILD-TYPE | 76 | 55 | 35 | 64 | 26 | 59 |
Figure S266. Get High-res Image Gene #57: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S267. Gene #58: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 9P LOSS MUTATED | 58 | 14 | 16 | 53 | 9 |
| 9P LOSS WILD-TYPE | 65 | 173 | 20 | 23 | 10 |
Figure S267. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S268. Gene #58: '9p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 9P LOSS MUTATED | 73 | 34 | 1 | 28 |
| 9P LOSS WILD-TYPE | 51 | 87 | 41 | 78 |
Figure S268. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00035 (Fisher's exact test), Q value = 0.0014
Table S269. Gene #58: '9p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 9P LOSS MUTATED | 65 | 10 | 22 | 24 |
| 9P LOSS WILD-TYPE | 75 | 48 | 56 | 56 |
Figure S269. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S270. Gene #58: '9p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 9P LOSS MUTATED | 7 | 13 | 18 | 10 | 35 |
| 9P LOSS WILD-TYPE | 55 | 49 | 26 | 30 | 29 |
Figure S270. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S271. Gene #58: '9p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 9P LOSS MUTATED | 42 | 36 | 69 |
| 9P LOSS WILD-TYPE | 130 | 94 | 63 |
Figure S271. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S272. Gene #58: '9p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 9P LOSS MUTATED | 68 | 18 | 61 |
| 9P LOSS WILD-TYPE | 175 | 64 | 48 |
Figure S272. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0288 (Fisher's exact test), Q value = 0.062
Table S273. Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 9P LOSS MUTATED | 38 | 15 | 18 | 21 | 13 | 17 |
| 9P LOSS WILD-TYPE | 35 | 42 | 41 | 39 | 20 | 42 |
Figure S273. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00038
Table S274. Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 9P LOSS MUTATED | 35 | 10 | 7 | 27 | 8 | 35 |
| 9P LOSS WILD-TYPE | 49 | 47 | 28 | 49 | 20 | 26 |
Figure S274. Get High-res Image Gene #58: '9p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S275. Gene #59: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 9Q LOSS MUTATED | 41 | 12 | 11 | 35 | 5 |
| 9Q LOSS WILD-TYPE | 82 | 175 | 25 | 41 | 14 |
Figure S275. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S276. Gene #59: '9q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 9Q LOSS MUTATED | 49 | 21 | 2 | 22 |
| 9Q LOSS WILD-TYPE | 75 | 100 | 40 | 84 |
Figure S276. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00655 (Fisher's exact test), Q value = 0.018
Table S277. Gene #59: '9q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 9Q LOSS MUTATED | 45 | 6 | 17 | 16 |
| 9Q LOSS WILD-TYPE | 95 | 52 | 61 | 64 |
Figure S277. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0011
Table S278. Gene #59: '9q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 9Q LOSS MUTATED | 7 | 11 | 13 | 5 | 27 |
| 9Q LOSS WILD-TYPE | 55 | 51 | 31 | 35 | 37 |
Figure S278. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S279. Gene #59: '9q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 9Q LOSS MUTATED | 28 | 23 | 51 |
| 9Q LOSS WILD-TYPE | 144 | 107 | 81 |
Figure S279. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S280. Gene #59: '9q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 9Q LOSS MUTATED | 45 | 11 | 46 |
| 9Q LOSS WILD-TYPE | 198 | 71 | 63 |
Figure S280. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0172 (Fisher's exact test), Q value = 0.04
Table S281. Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 9Q LOSS MUTATED | 28 | 8 | 10 | 13 | 10 | 12 |
| 9Q LOSS WILD-TYPE | 45 | 49 | 49 | 47 | 23 | 47 |
Figure S281. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00206 (Fisher's exact test), Q value = 0.0065
Table S282. Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 9Q LOSS MUTATED | 19 | 7 | 5 | 16 | 7 | 27 |
| 9Q LOSS WILD-TYPE | 65 | 50 | 30 | 60 | 21 | 34 |
Figure S282. Get High-res Image Gene #59: '9q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S283. Gene #60: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 10P LOSS MUTATED | 34 | 8 | 3 | 12 | 7 |
| 10P LOSS WILD-TYPE | 89 | 179 | 33 | 64 | 12 |
Figure S283. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00064 (Fisher's exact test), Q value = 0.0024
Table S284. Gene #60: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 10P LOSS MUTATED | 30 | 15 | 1 | 10 |
| 10P LOSS WILD-TYPE | 94 | 106 | 41 | 96 |
Figure S284. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0298 (Fisher's exact test), Q value = 0.064
Table S285. Gene #60: '10p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 10P LOSS MUTATED | 24 | 3 | 15 | 7 |
| 10P LOSS WILD-TYPE | 116 | 55 | 63 | 73 |
Figure S285. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S286. Gene #60: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 10P LOSS MUTATED | 21 | 8 | 34 |
| 10P LOSS WILD-TYPE | 151 | 122 | 98 |
Figure S286. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.00063
Table S287. Gene #60: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 10P LOSS MUTATED | 33 | 3 | 27 |
| 10P LOSS WILD-TYPE | 210 | 79 | 82 |
Figure S287. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0131 (Fisher's exact test), Q value = 0.033
Table S288. Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 10P LOSS MUTATED | 17 | 4 | 1 | 10 | 1 | 13 |
| 10P LOSS WILD-TYPE | 67 | 53 | 34 | 66 | 27 | 48 |
Figure S288. Get High-res Image Gene #60: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S289. Gene #61: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 10Q LOSS MUTATED | 42 | 6 | 7 | 7 | 5 |
| 10Q LOSS WILD-TYPE | 81 | 181 | 29 | 69 | 14 |
Figure S289. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S290. Gene #61: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 10Q LOSS MUTATED | 35 | 13 | 1 | 9 |
| 10Q LOSS WILD-TYPE | 89 | 108 | 41 | 97 |
Figure S290. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0189 (Fisher's exact test), Q value = 0.044
Table S291. Gene #61: '10q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 10Q LOSS MUTATED | 27 | 2 | 11 | 9 |
| 10Q LOSS WILD-TYPE | 113 | 56 | 67 | 71 |
Figure S291. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00822 (Fisher's exact test), Q value = 0.022
Table S292. Gene #61: '10q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 10Q LOSS MUTATED | 4 | 3 | 4 | 7 | 15 |
| 10Q LOSS WILD-TYPE | 58 | 59 | 40 | 33 | 49 |
Figure S292. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S293. Gene #61: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 10Q LOSS MUTATED | 24 | 8 | 34 |
| 10Q LOSS WILD-TYPE | 148 | 122 | 98 |
Figure S293. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S294. Gene #61: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 10Q LOSS MUTATED | 30 | 5 | 31 |
| 10Q LOSS WILD-TYPE | 213 | 77 | 78 |
Figure S294. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00991 (Fisher's exact test), Q value = 0.026
Table S295. Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 10Q LOSS MUTATED | 18 | 2 | 2 | 9 | 3 | 13 |
| 10Q LOSS WILD-TYPE | 66 | 55 | 33 | 67 | 25 | 48 |
Figure S295. Get High-res Image Gene #61: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S296. Gene #62: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 11P LOSS MUTATED | 33 | 7 | 6 | 16 | 0 |
| 11P LOSS WILD-TYPE | 90 | 180 | 30 | 60 | 19 |
Figure S296. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00132 (Fisher's exact test), Q value = 0.0045
Table S297. Gene #62: '11p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 11P LOSS MUTATED | 29 | 13 | 1 | 11 |
| 11P LOSS WILD-TYPE | 95 | 108 | 41 | 95 |
Figure S297. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0326 (Fisher's exact test), Q value = 0.068
Table S298. Gene #62: '11p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 11P LOSS MUTATED | 29 | 5 | 7 | 8 |
| 11P LOSS WILD-TYPE | 111 | 53 | 71 | 72 |
Figure S298. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0122 (Fisher's exact test), Q value = 0.031
Table S299. Gene #62: '11p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 11P LOSS MUTATED | 31 | 6 | 24 |
| 11P LOSS WILD-TYPE | 212 | 76 | 85 |
Figure S299. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0131 (Fisher's exact test), Q value = 0.033
Table S300. Gene #62: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 11P LOSS MUTATED | 13 | 4 | 3 | 10 | 0 | 15 |
| 11P LOSS WILD-TYPE | 71 | 53 | 32 | 66 | 28 | 46 |
Figure S300. Get High-res Image Gene #62: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S301. Gene #63: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 11Q LOSS MUTATED | 28 | 10 | 6 | 15 | 2 |
| 11Q LOSS WILD-TYPE | 95 | 177 | 30 | 61 | 17 |
Figure S301. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0205 (Fisher's exact test), Q value = 0.047
Table S302. Gene #63: '11q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 11Q LOSS MUTATED | 27 | 14 | 2 | 12 |
| 11Q LOSS WILD-TYPE | 97 | 107 | 40 | 94 |
Figure S302. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0324 (Fisher's exact test), Q value = 0.068
Table S303. Gene #63: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 11Q LOSS MUTATED | 12 | 4 | 4 | 11 | 0 | 14 |
| 11Q LOSS WILD-TYPE | 72 | 53 | 31 | 65 | 28 | 47 |
Figure S303. Get High-res Image Gene #63: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S304. Gene #64: '12p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 12P LOSS MUTATED | 41 | 2 | 5 | 13 | 2 |
| 12P LOSS WILD-TYPE | 82 | 185 | 31 | 63 | 17 |
Figure S304. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S305. Gene #64: '12p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 12P LOSS MUTATED | 41 | 6 | 1 | 5 |
| 12P LOSS WILD-TYPE | 83 | 115 | 41 | 101 |
Figure S305. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 7e-05 (Fisher's exact test), Q value = 0.00035
Table S306. Gene #64: '12p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 12P LOSS MUTATED | 3 | 3 | 6 | 3 | 20 |
| 12P LOSS WILD-TYPE | 59 | 59 | 38 | 37 | 44 |
Figure S306. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0135 (Fisher's exact test), Q value = 0.034
Table S307. Gene #64: '12p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 12P LOSS MUTATED | 22 | 3 | 10 |
| 12P LOSS WILD-TYPE | 88 | 54 | 95 |
Figure S307. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S308. Gene #64: '12p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 12P LOSS MUTATED | 17 | 10 | 34 |
| 12P LOSS WILD-TYPE | 155 | 120 | 98 |
Figure S308. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S309. Gene #64: '12p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 12P LOSS MUTATED | 23 | 5 | 33 |
| 12P LOSS WILD-TYPE | 220 | 77 | 76 |
Figure S309. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0387 (Fisher's exact test), Q value = 0.08
Table S310. Gene #64: '12p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 12P LOSS MUTATED | 19 | 6 | 4 | 10 | 3 | 7 |
| 12P LOSS WILD-TYPE | 54 | 51 | 55 | 50 | 30 | 52 |
Figure S310. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S311. Gene #64: '12p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 12P LOSS MUTATED | 15 | 2 | 1 | 7 | 3 | 21 |
| 12P LOSS WILD-TYPE | 69 | 55 | 34 | 69 | 25 | 40 |
Figure S311. Get High-res Image Gene #64: '12p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S312. Gene #65: '12q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 12Q LOSS MUTATED | 34 | 1 | 3 | 12 | 2 |
| 12Q LOSS WILD-TYPE | 89 | 186 | 33 | 64 | 17 |
Figure S312. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S313. Gene #65: '12q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 12Q LOSS MUTATED | 33 | 5 | 0 | 7 |
| 12Q LOSS WILD-TYPE | 91 | 116 | 42 | 99 |
Figure S313. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00086 (Fisher's exact test), Q value = 0.0032
Table S314. Gene #65: '12q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 12Q LOSS MUTATED | 2 | 2 | 6 | 3 | 15 |
| 12Q LOSS WILD-TYPE | 60 | 60 | 38 | 37 | 49 |
Figure S314. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0393 (Fisher's exact test), Q value = 0.081
Table S315. Gene #65: '12q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 12Q LOSS MUTATED | 17 | 10 | 23 |
| 12Q LOSS WILD-TYPE | 155 | 120 | 109 |
Figure S315. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00027
Table S316. Gene #65: '12q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 12Q LOSS MUTATED | 20 | 4 | 26 |
| 12Q LOSS WILD-TYPE | 223 | 78 | 83 |
Figure S316. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00106 (Fisher's exact test), Q value = 0.0038
Table S317. Gene #65: '12q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 12Q LOSS MUTATED | 12 | 2 | 1 | 9 | 2 | 17 |
| 12Q LOSS WILD-TYPE | 72 | 55 | 34 | 67 | 26 | 44 |
Figure S317. Get High-res Image Gene #65: '12q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00354 (Fisher's exact test), Q value = 0.011
Table S318. Gene #66: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 13Q LOSS MUTATED | 12 | 7 | 2 | 14 | 1 |
| 13Q LOSS WILD-TYPE | 111 | 180 | 34 | 62 | 18 |
Figure S318. Get High-res Image Gene #66: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S319. Gene #67: '14q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 14Q LOSS MUTATED | 47 | 17 | 5 | 37 | 5 |
| 14Q LOSS WILD-TYPE | 76 | 170 | 31 | 39 | 14 |
Figure S319. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S320. Gene #67: '14q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 14Q LOSS MUTATED | 55 | 24 | 5 | 16 |
| 14Q LOSS WILD-TYPE | 69 | 97 | 37 | 90 |
Figure S320. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00194 (Fisher's exact test), Q value = 0.0062
Table S321. Gene #67: '14q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 14Q LOSS MUTATED | 9 | 13 | 11 | 5 | 27 |
| 14Q LOSS WILD-TYPE | 53 | 49 | 33 | 35 | 37 |
Figure S321. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0197 (Fisher's exact test), Q value = 0.045
Table S322. Gene #67: '14q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 14Q LOSS MUTATED | 36 | 11 | 18 |
| 14Q LOSS WILD-TYPE | 74 | 46 | 87 |
Figure S322. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.00052
Table S323. Gene #67: '14q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 14Q LOSS MUTATED | 33 | 24 | 51 |
| 14Q LOSS WILD-TYPE | 139 | 106 | 81 |
Figure S323. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S324. Gene #67: '14q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 14Q LOSS MUTATED | 48 | 14 | 46 |
| 14Q LOSS WILD-TYPE | 195 | 68 | 63 |
Figure S324. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00778 (Fisher's exact test), Q value = 0.021
Table S325. Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 14Q LOSS MUTATED | 16 | 9 | 5 | 23 | 5 | 25 |
| 14Q LOSS WILD-TYPE | 68 | 48 | 30 | 53 | 23 | 36 |
Figure S325. Get High-res Image Gene #67: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S326. Gene #68: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 15Q LOSS MUTATED | 43 | 13 | 9 | 22 | 3 |
| 15Q LOSS WILD-TYPE | 80 | 174 | 27 | 54 | 16 |
Figure S326. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00172 (Fisher's exact test), Q value = 0.0056
Table S327. Gene #68: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 15Q LOSS MUTATED | 41 | 20 | 5 | 17 |
| 15Q LOSS WILD-TYPE | 83 | 101 | 37 | 89 |
Figure S327. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0177 (Fisher's exact test), Q value = 0.041
Table S328. Gene #68: '15q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 15Q LOSS MUTATED | 5 | 15 | 22 | 9 | 16 |
| 15Q LOSS WILD-TYPE | 25 | 77 | 60 | 84 | 43 |
Figure S328. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00091 (Fisher's exact test), Q value = 0.0033
Table S329. Gene #68: '15q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 15Q LOSS MUTATED | 8 | 4 | 9 | 5 | 22 |
| 15Q LOSS WILD-TYPE | 54 | 58 | 35 | 35 | 42 |
Figure S329. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00021 (Fisher's exact test), Q value = 9e-04
Table S330. Gene #68: '15q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 15Q LOSS MUTATED | 30 | 2 | 16 |
| 15Q LOSS WILD-TYPE | 80 | 55 | 89 |
Figure S330. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0175 (Fisher's exact test), Q value = 0.041
Table S331. Gene #68: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 15Q LOSS MUTATED | 33 | 18 | 37 |
| 15Q LOSS WILD-TYPE | 139 | 112 | 95 |
Figure S331. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00442 (Fisher's exact test), Q value = 0.013
Table S332. Gene #68: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 15Q LOSS MUTATED | 43 | 11 | 34 |
| 15Q LOSS WILD-TYPE | 200 | 71 | 75 |
Figure S332. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00164 (Fisher's exact test), Q value = 0.0054
Table S333. Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 15Q LOSS MUTATED | 18 | 5 | 2 | 17 | 5 | 22 |
| 15Q LOSS WILD-TYPE | 66 | 52 | 33 | 59 | 23 | 39 |
Figure S333. Get High-res Image Gene #68: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S334. Gene #69: '16p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 16P LOSS MUTATED | 55 | 10 | 4 | 29 | 2 |
| 16P LOSS WILD-TYPE | 68 | 177 | 32 | 47 | 17 |
Figure S334. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S335. Gene #69: '16p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 16P LOSS MUTATED | 51 | 23 | 1 | 15 |
| 16P LOSS WILD-TYPE | 73 | 98 | 41 | 91 |
Figure S335. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S336. Gene #69: '16p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 16P LOSS MUTATED | 7 | 6 | 3 | 5 | 32 |
| 16P LOSS WILD-TYPE | 55 | 56 | 41 | 35 | 32 |
Figure S336. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00285 (Fisher's exact test), Q value = 0.0086
Table S337. Gene #69: '16p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 16P LOSS MUTATED | 32 | 5 | 16 |
| 16P LOSS WILD-TYPE | 78 | 52 | 89 |
Figure S337. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S338. Gene #69: '16p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 16P LOSS MUTATED | 28 | 17 | 54 |
| 16P LOSS WILD-TYPE | 144 | 113 | 78 |
Figure S338. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S339. Gene #69: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 16P LOSS MUTATED | 43 | 10 | 46 |
| 16P LOSS WILD-TYPE | 200 | 72 | 63 |
Figure S339. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S340. Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 16P LOSS MUTATED | 32 | 14 | 5 | 9 | 13 | 6 |
| 16P LOSS WILD-TYPE | 41 | 43 | 54 | 51 | 20 | 53 |
Figure S340. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S341. Gene #69: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 16P LOSS MUTATED | 21 | 5 | 2 | 20 | 2 | 29 |
| 16P LOSS WILD-TYPE | 63 | 52 | 33 | 56 | 26 | 32 |
Figure S341. Get High-res Image Gene #69: '16p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S342. Gene #70: '16q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 16Q LOSS MUTATED | 60 | 16 | 3 | 32 | 4 |
| 16Q LOSS WILD-TYPE | 63 | 171 | 33 | 44 | 15 |
Figure S342. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S343. Gene #70: '16q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 16Q LOSS MUTATED | 60 | 20 | 1 | 22 |
| 16Q LOSS WILD-TYPE | 64 | 101 | 41 | 84 |
Figure S343. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S344. Gene #70: '16q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 16Q LOSS MUTATED | 6 | 11 | 8 | 6 | 33 |
| 16Q LOSS WILD-TYPE | 56 | 51 | 36 | 34 | 31 |
Figure S344. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0305 (Fisher's exact test), Q value = 0.065
Table S345. Gene #70: '16q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 16Q LOSS MUTATED | 35 | 9 | 20 |
| 16Q LOSS WILD-TYPE | 75 | 48 | 85 |
Figure S345. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S346. Gene #70: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 16Q LOSS MUTATED | 31 | 24 | 58 |
| 16Q LOSS WILD-TYPE | 141 | 106 | 74 |
Figure S346. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S347. Gene #70: '16q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 16Q LOSS MUTATED | 50 | 14 | 49 |
| 16Q LOSS WILD-TYPE | 193 | 68 | 60 |
Figure S347. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00013 (Fisher's exact test), Q value = 0.00059
Table S348. Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 16Q LOSS MUTATED | 34 | 14 | 9 | 9 | 12 | 12 |
| 16Q LOSS WILD-TYPE | 39 | 43 | 50 | 51 | 21 | 47 |
Figure S348. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S349. Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 16Q LOSS MUTATED | 27 | 10 | 2 | 18 | 2 | 31 |
| 16Q LOSS WILD-TYPE | 57 | 47 | 33 | 58 | 26 | 30 |
Figure S349. Get High-res Image Gene #70: '16q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S350. Gene #71: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 17P LOSS MUTATED | 76 | 17 | 16 | 48 | 7 |
| 17P LOSS WILD-TYPE | 47 | 170 | 20 | 28 | 12 |
Figure S350. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S351. Gene #71: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 17P LOSS MUTATED | 78 | 42 | 4 | 24 |
| 17P LOSS WILD-TYPE | 46 | 79 | 38 | 82 |
Figure S351. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0131 (Fisher's exact test), Q value = 0.033
Table S352. Gene #71: '17p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 17P LOSS MUTATED | 18 | 39 | 25 | 26 | 23 |
| 17P LOSS WILD-TYPE | 12 | 53 | 57 | 67 | 36 |
Figure S352. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0036 (Fisher's exact test), Q value = 0.011
Table S353. Gene #71: '17p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 17P LOSS MUTATED | 65 | 14 | 31 | 21 |
| 17P LOSS WILD-TYPE | 75 | 44 | 47 | 59 |
Figure S353. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00026 (Fisher's exact test), Q value = 0.0011
Table S354. Gene #71: '17p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 17P LOSS MUTATED | 14 | 11 | 17 | 13 | 34 |
| 17P LOSS WILD-TYPE | 48 | 51 | 27 | 27 | 30 |
Figure S354. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00499 (Fisher's exact test), Q value = 0.014
Table S355. Gene #71: '17p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 17P LOSS MUTATED | 46 | 10 | 33 |
| 17P LOSS WILD-TYPE | 64 | 47 | 72 |
Figure S355. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S356. Gene #71: '17p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 17P LOSS MUTATED | 59 | 28 | 72 |
| 17P LOSS WILD-TYPE | 113 | 102 | 60 |
Figure S356. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S357. Gene #71: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 17P LOSS MUTATED | 83 | 15 | 61 |
| 17P LOSS WILD-TYPE | 160 | 67 | 48 |
Figure S357. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S358. Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 17P LOSS MUTATED | 34 | 8 | 7 | 37 | 6 | 34 |
| 17P LOSS WILD-TYPE | 50 | 49 | 28 | 39 | 22 | 27 |
Figure S358. Get High-res Image Gene #71: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S359. Gene #72: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 17Q LOSS MUTATED | 39 | 8 | 5 | 18 | 4 |
| 17Q LOSS WILD-TYPE | 84 | 179 | 31 | 58 | 15 |
Figure S359. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S360. Gene #72: '17q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 17Q LOSS MUTATED | 37 | 14 | 0 | 13 |
| 17Q LOSS WILD-TYPE | 87 | 107 | 42 | 93 |
Figure S360. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.046 (Fisher's exact test), Q value = 0.092
Table S361. Gene #72: '17q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 17Q LOSS MUTATED | 29 | 6 | 16 | 7 |
| 17Q LOSS WILD-TYPE | 111 | 52 | 62 | 73 |
Figure S361. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0111 (Fisher's exact test), Q value = 0.028
Table S362. Gene #72: '17q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 17Q LOSS MUTATED | 6 | 4 | 6 | 6 | 18 |
| 17Q LOSS WILD-TYPE | 56 | 58 | 38 | 34 | 46 |
Figure S362. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00065 (Fisher's exact test), Q value = 0.0025
Table S363. Gene #72: '17q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 17Q LOSS MUTATED | 25 | 12 | 35 |
| 17Q LOSS WILD-TYPE | 147 | 118 | 97 |
Figure S363. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S364. Gene #72: '17q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 17Q LOSS MUTATED | 31 | 7 | 34 |
| 17Q LOSS WILD-TYPE | 212 | 75 | 75 |
Figure S364. Get High-res Image Gene #72: '17q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 0.00013
Table S365. Gene #73: '18p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 18P LOSS MUTATED | 42 | 28 | 13 | 33 | 3 |
| 18P LOSS WILD-TYPE | 81 | 159 | 23 | 43 | 16 |
Figure S365. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0361 (Fisher's exact test), Q value = 0.075
Table S366. Gene #73: '18p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 18P LOSS MUTATED | 38 | 14 | 20 |
| 18P LOSS WILD-TYPE | 72 | 43 | 85 |
Figure S366. Get High-res Image Gene #73: '18p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S367. Gene #74: '18q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 18Q LOSS MUTATED | 66 | 30 | 17 | 38 | 3 |
| 18Q LOSS WILD-TYPE | 57 | 157 | 19 | 38 | 16 |
Figure S367. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00019 (Fisher's exact test), Q value = 0.00082
Table S368. Gene #74: '18q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 18Q LOSS MUTATED | 59 | 31 | 19 | 27 |
| 18Q LOSS WILD-TYPE | 65 | 90 | 23 | 79 |
Figure S368. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0475 (Fisher's exact test), Q value = 0.094
Table S369. Gene #74: '18q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 18Q LOSS MUTATED | 59 | 15 | 33 | 23 |
| 18Q LOSS WILD-TYPE | 81 | 43 | 45 | 57 |
Figure S369. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00062 (Fisher's exact test), Q value = 0.0024
Table S370. Gene #74: '18q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 18Q LOSS MUTATED | 50 | 13 | 24 |
| 18Q LOSS WILD-TYPE | 60 | 44 | 81 |
Figure S370. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00031
Table S371. Gene #74: '18q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 18Q LOSS MUTATED | 53 | 33 | 65 |
| 18Q LOSS WILD-TYPE | 119 | 97 | 67 |
Figure S371. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00104 (Fisher's exact test), Q value = 0.0038
Table S372. Gene #74: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 18Q LOSS MUTATED | 78 | 20 | 53 |
| 18Q LOSS WILD-TYPE | 165 | 62 | 56 |
Figure S372. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00105 (Fisher's exact test), Q value = 0.0038
Table S373. Gene #74: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 18Q LOSS MUTATED | 26 | 10 | 8 | 25 | 10 | 33 |
| 18Q LOSS WILD-TYPE | 58 | 47 | 27 | 51 | 18 | 28 |
Figure S373. Get High-res Image Gene #74: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S374. Gene #75: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 19P LOSS MUTATED | 66 | 4 | 8 | 30 | 7 |
| 19P LOSS WILD-TYPE | 57 | 183 | 28 | 46 | 12 |
Figure S374. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S375. Gene #75: '19p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 19P LOSS MUTATED | 70 | 22 | 4 | 9 |
| 19P LOSS WILD-TYPE | 54 | 99 | 38 | 97 |
Figure S375. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00543 (Fisher's exact test), Q value = 0.015
Table S376. Gene #75: '19p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 19P LOSS MUTATED | 48 | 7 | 19 | 16 |
| 19P LOSS WILD-TYPE | 92 | 51 | 59 | 64 |
Figure S376. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S377. Gene #75: '19p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 19P LOSS MUTATED | 8 | 3 | 7 | 5 | 32 |
| 19P LOSS WILD-TYPE | 54 | 59 | 37 | 35 | 32 |
Figure S377. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-04 (Fisher's exact test), Q value = 0.00086
Table S378. Gene #75: '19p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 19P LOSS MUTATED | 35 | 4 | 16 |
| 19P LOSS WILD-TYPE | 75 | 53 | 89 |
Figure S378. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S379. Gene #75: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 19P LOSS MUTATED | 30 | 16 | 67 |
| 19P LOSS WILD-TYPE | 142 | 114 | 65 |
Figure S379. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S380. Gene #75: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 19P LOSS MUTATED | 41 | 9 | 63 |
| 19P LOSS WILD-TYPE | 202 | 73 | 46 |
Figure S380. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00022
Table S381. Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 19P LOSS MUTATED | 36 | 13 | 12 | 14 | 7 | 7 |
| 19P LOSS WILD-TYPE | 37 | 44 | 47 | 46 | 26 | 52 |
Figure S381. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S382. Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 19P LOSS MUTATED | 26 | 5 | 3 | 18 | 1 | 36 |
| 19P LOSS WILD-TYPE | 58 | 52 | 32 | 58 | 27 | 25 |
Figure S382. Get High-res Image Gene #75: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S383. Gene #76: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 19Q LOSS MUTATED | 51 | 4 | 7 | 18 | 7 |
| 19Q LOSS WILD-TYPE | 72 | 183 | 29 | 58 | 12 |
Figure S383. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S384. Gene #76: '19q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 19Q LOSS MUTATED | 53 | 16 | 1 | 7 |
| 19Q LOSS WILD-TYPE | 71 | 105 | 41 | 99 |
Figure S384. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S385. Gene #76: '19q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 19Q LOSS MUTATED | 5 | 2 | 7 | 6 | 23 |
| 19Q LOSS WILD-TYPE | 57 | 60 | 37 | 34 | 41 |
Figure S385. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0229 (Fisher's exact test), Q value = 0.051
Table S386. Gene #76: '19q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 110 | 57 | 105 |
| 19Q LOSS MUTATED | 23 | 3 | 17 |
| 19Q LOSS WILD-TYPE | 87 | 54 | 88 |
Figure S386. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S387. Gene #76: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 19Q LOSS MUTATED | 24 | 11 | 51 |
| 19Q LOSS WILD-TYPE | 148 | 119 | 81 |
Figure S387. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S388. Gene #76: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 19Q LOSS MUTATED | 29 | 7 | 50 |
| 19Q LOSS WILD-TYPE | 214 | 75 | 59 |
Figure S388. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00051 (Fisher's exact test), Q value = 0.002
Table S389. Gene #76: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 19Q LOSS MUTATED | 27 | 12 | 11 | 7 | 5 | 4 |
| 19Q LOSS WILD-TYPE | 46 | 45 | 48 | 53 | 28 | 55 |
Figure S389. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S390. Gene #76: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 19Q LOSS MUTATED | 23 | 3 | 2 | 11 | 0 | 27 |
| 19Q LOSS WILD-TYPE | 61 | 54 | 33 | 65 | 28 | 34 |
Figure S390. Get High-res Image Gene #76: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00241 (Fisher's exact test), Q value = 0.0074
Table S391. Gene #77: '20p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 20P LOSS MUTATED | 10 | 2 | 2 | 8 | 0 |
| 20P LOSS WILD-TYPE | 113 | 185 | 34 | 68 | 19 |
Figure S391. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0157 (Fisher's exact test), Q value = 0.038
Table S392. Gene #77: '20p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 20P LOSS MUTATED | 13 | 4 | 0 | 3 |
| 20P LOSS WILD-TYPE | 111 | 117 | 42 | 103 |
Figure S392. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00637 (Fisher's exact test), Q value = 0.017
Table S393. Gene #77: '20p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 30 | 92 | 82 | 93 | 59 |
| 20P LOSS MUTATED | 2 | 2 | 3 | 1 | 8 |
| 20P LOSS WILD-TYPE | 28 | 90 | 79 | 92 | 51 |
Figure S393. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00153 (Fisher's exact test), Q value = 0.0051
Table S394. Gene #77: '20p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 20P LOSS MUTATED | 0 | 2 | 7 | 0 | 4 |
| 20P LOSS WILD-TYPE | 62 | 60 | 37 | 40 | 60 |
Figure S394. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0386 (Fisher's exact test), Q value = 0.08
Table S395. Gene #77: '20p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 20P LOSS MUTATED | 5 | 4 | 12 |
| 20P LOSS WILD-TYPE | 167 | 126 | 120 |
Figure S395. Get High-res Image Gene #77: '20p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S396. Gene #78: '21q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 21Q LOSS MUTATED | 68 | 35 | 16 | 50 | 11 |
| 21Q LOSS WILD-TYPE | 55 | 152 | 20 | 26 | 8 |
Figure S396. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00017
Table S397. Gene #78: '21q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 21Q LOSS MUTATED | 68 | 49 | 5 | 41 |
| 21Q LOSS WILD-TYPE | 56 | 72 | 37 | 65 |
Figure S397. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.0012
Table S398. Gene #78: '21q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 21Q LOSS MUTATED | 61 | 43 | 73 |
| 21Q LOSS WILD-TYPE | 111 | 87 | 59 |
Figure S398. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00131 (Fisher's exact test), Q value = 0.0045
Table S399. Gene #78: '21q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 21Q LOSS MUTATED | 92 | 25 | 60 |
| 21Q LOSS WILD-TYPE | 151 | 57 | 49 |
Figure S399. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0064 (Fisher's exact test), Q value = 0.018
Table S400. Gene #78: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 21Q LOSS MUTATED | 37 | 27 | 17 | 24 | 20 | 17 |
| 21Q LOSS WILD-TYPE | 36 | 30 | 42 | 36 | 13 | 42 |
Figure S400. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00221 (Fisher's exact test), Q value = 0.0069
Table S401. Gene #78: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 21Q LOSS MUTATED | 34 | 17 | 8 | 39 | 9 | 35 |
| 21Q LOSS WILD-TYPE | 50 | 40 | 27 | 37 | 19 | 26 |
Figure S401. Get High-res Image Gene #78: '21q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S402. Gene #79: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| 22Q LOSS MUTATED | 67 | 17 | 11 | 43 | 8 |
| 22Q LOSS WILD-TYPE | 56 | 170 | 25 | 33 | 11 |
Figure S402. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S403. Gene #79: '22q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| 22Q LOSS MUTATED | 70 | 35 | 2 | 26 |
| 22Q LOSS WILD-TYPE | 54 | 86 | 40 | 80 |
Figure S403. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00224 (Fisher's exact test), Q value = 0.007
Table S404. Gene #79: '22q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 140 | 58 | 78 | 80 |
| 22Q LOSS MUTATED | 57 | 9 | 27 | 20 |
| 22Q LOSS WILD-TYPE | 83 | 49 | 51 | 60 |
Figure S404. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00049 (Fisher's exact test), Q value = 0.0019
Table S405. Gene #79: '22q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 62 | 62 | 44 | 40 | 64 |
| 22Q LOSS MUTATED | 10 | 14 | 14 | 9 | 32 |
| 22Q LOSS WILD-TYPE | 52 | 48 | 30 | 31 | 32 |
Figure S405. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S406. Gene #79: '22q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 172 | 130 | 132 |
| 22Q LOSS MUTATED | 43 | 31 | 69 |
| 22Q LOSS WILD-TYPE | 129 | 99 | 63 |
Figure S406. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S407. Gene #79: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 243 | 82 | 109 |
| 22Q LOSS MUTATED | 66 | 17 | 60 |
| 22Q LOSS WILD-TYPE | 177 | 65 | 49 |
Figure S407. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00213 (Fisher's exact test), Q value = 0.0067
Table S408. Gene #79: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| 22Q LOSS MUTATED | 35 | 22 | 15 | 14 | 16 | 13 |
| 22Q LOSS WILD-TYPE | 38 | 35 | 44 | 46 | 17 | 46 |
Figure S408. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00038
Table S409. Gene #79: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| 22Q LOSS MUTATED | 30 | 13 | 4 | 30 | 5 | 33 |
| 22Q LOSS WILD-TYPE | 54 | 44 | 31 | 46 | 23 | 28 |
Figure S409. Get High-res Image Gene #79: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S410. Gene #80: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| XP LOSS MUTATED | 31 | 6 | 4 | 17 | 1 |
| XP LOSS WILD-TYPE | 92 | 181 | 32 | 59 | 18 |
Figure S410. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0039 (Fisher's exact test), Q value = 0.011
Table S411. Gene #80: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| XP LOSS MUTATED | 22 | 22 | 2 | 6 |
| XP LOSS WILD-TYPE | 102 | 99 | 40 | 100 |
Figure S411. Get High-res Image Gene #80: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 6.7e-05
Table S412. Gene #81: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 123 | 187 | 36 | 76 | 19 |
| XQ LOSS MUTATED | 22 | 4 | 2 | 20 | 2 |
| XQ LOSS WILD-TYPE | 101 | 183 | 34 | 56 | 17 |
Figure S412. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0041 (Fisher's exact test), Q value = 0.012
Table S413. Gene #81: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 124 | 121 | 42 | 106 |
| XQ LOSS MUTATED | 21 | 16 | 2 | 4 |
| XQ LOSS WILD-TYPE | 103 | 105 | 40 | 102 |
Figure S413. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.021 (Fisher's exact test), Q value = 0.047
Table S414. Gene #81: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 73 | 57 | 59 | 60 | 33 | 59 |
| XQ LOSS MUTATED | 16 | 5 | 4 | 8 | 4 | 2 |
| XQ LOSS WILD-TYPE | 57 | 52 | 55 | 52 | 29 | 57 |
Figure S414. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0465 (Fisher's exact test), Q value = 0.093
Table S415. Gene #81: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 |
|---|---|---|---|---|---|---|
| ALL | 84 | 57 | 35 | 76 | 28 | 61 |
| XQ LOSS MUTATED | 15 | 2 | 1 | 11 | 2 | 8 |
| XQ LOSS WILD-TYPE | 69 | 55 | 34 | 65 | 26 | 53 |
Figure S415. Get High-res Image Gene #81: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
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Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
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Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/STAD-TP/19782337/transformed.cor.cli.txt
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Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/STAD-TP/20140953/STAD-TP.transferedmergedcluster.txt
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Number of patients = 441
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Number of significantly arm-level cnvs = 81
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Number of molecular subtypes = 10
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Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.