This pipeline computes the correlation between significant arm-level copy number variations (cnvs) and molecular subtypes.
Testing the association between copy number variation 74 arm-level events and 10 molecular subtypes across 150 patients, 371 significant findings detected with P value < 0.05 and Q value < 0.25.
-
1p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
1q gain cnv correlated to 'MIRSEQ_CNMF'.
-
2p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
2q gain cnv correlated to 'METHLYATION_CNMF'.
-
3p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
3q gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
5p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
5q gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
6p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
6q gain cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
7p gain cnv correlated to 'CN_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
7q gain cnv correlated to 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
8p gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
8q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
11q gain cnv correlated to 'RPPA_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
-
12q gain cnv correlated to 'MIRSEQ_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
15q gain cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
16p gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
16q gain cnv correlated to 'CN_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
17p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
17q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
19p gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
19q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
20p gain cnv correlated to 'CN_CNMF' and 'MRNASEQ_CNMF'.
-
20q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
22q gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
xp gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
xq gain cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
1p loss cnv correlated to 'MIRSEQ_CNMF'.
-
3p loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
3q loss cnv correlated to 'RPPA_CNMF' and 'MIRSEQ_MATURE_CNMF'.
-
4p loss cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CNMF'.
-
4q loss cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
5p loss cnv correlated to 'RPPA_CNMF'.
-
5q loss cnv correlated to 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
6p loss cnv correlated to 'METHLYATION_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
-
6q loss cnv correlated to 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CNMF'.
-
8p loss cnv correlated to 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
8q loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
9p loss cnv correlated to 'CN_CNMF'.
-
9q loss cnv correlated to 'CN_CNMF' and 'MRNASEQ_CHIERARCHICAL'.
-
10p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
10q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
11p loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
11q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
13q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
14q loss cnv correlated to 'METHLYATION_CNMF', 'RPPA_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
15q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
16p loss cnv correlated to 'METHLYATION_CNMF', 'MIRSEQ_CNMF', and 'MIRSEQ_CHIERARCHICAL'.
-
16q loss cnv correlated to 'MIRSEQ_CNMF'.
-
17p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
17q loss cnv correlated to 'CN_CNMF', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
18p loss cnv correlated to 'MRNASEQ_CNMF' and 'MIRSEQ_CHIERARCHICAL'.
-
18q loss cnv correlated to 'MIRSEQ_CHIERARCHICAL' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
19p loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
19q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
20p loss cnv correlated to 'MIRSEQ_CNMF' and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
22q loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'RPPA_CNMF', 'RPPA_CHIERARCHICAL', 'MRNASEQ_CNMF', 'MRNASEQ_CHIERARCHICAL', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', 'MIRSEQ_MATURE_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
xp loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
-
xq loss cnv correlated to 'CN_CNMF', 'METHLYATION_CNMF', 'MIRSEQ_CNMF', 'MIRSEQ_CHIERARCHICAL', and 'MIRSEQ_MATURE_CHIERARCHICAL'.
Table 1. Get Full Table Overview of the association between significant copy number variation of 74 arm-level events and 10 molecular subtypes. Shown in the table are P values (Q values). Thresholded by P value < 0.05 and Q value < 0.25, 371 significant findings detected.
|
Clinical Features |
CN CNMF |
METHLYATION CNMF |
RPPA CNMF |
RPPA CHIERARCHICAL |
MRNASEQ CNMF |
MRNASEQ CHIERARCHICAL |
MIRSEQ CNMF |
MIRSEQ CHIERARCHICAL |
MIRSEQ MATURE CNMF |
MIRSEQ MATURE CHIERARCHICAL |
||
| nCNV (%) | nWild-Type | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | Fisher's exact test | |
| 1p gain | 37 (25%) | 113 |
0.00282 (0.0115) |
0.0005 (0.00306) |
0.00317 (0.0125) |
0.011 (0.0312) |
0.00035 (0.00231) |
0.00221 (0.00997) |
0.00016 (0.00123) |
0.00012 (0.000955) |
1e-05 (0.000121) |
0.00052 (0.00313) |
| 8q gain | 111 (74%) | 39 |
0.0205 (0.0498) |
0.00271 (0.0111) |
0.0121 (0.0335) |
0.00245 (0.0104) |
0.00017 (0.00128) |
0.00034 (0.00227) |
0.00011 (0.000894) |
0.00012 (0.000955) |
0.0004 (0.00257) |
0.00031 (0.0021) |
| 17p gain | 40 (27%) | 110 |
1e-05 (0.000121) |
1e-05 (0.000121) |
3e-05 (0.000288) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
| 17q gain | 51 (34%) | 99 |
0.00025 (0.0018) |
6e-05 (0.000522) |
2e-05 (0.000203) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
| 19p gain | 36 (24%) | 114 |
0.0101 (0.0295) |
0.00011 (0.000894) |
0.00939 (0.0278) |
0.00318 (0.0125) |
0.0001 (0.000831) |
0.00091 (0.00503) |
0.0438 (0.0901) |
5e-05 (0.000457) |
0.00046 (0.00284) |
3e-05 (0.000288) |
| xp gain | 22 (15%) | 128 |
0.0006 (0.00352) |
0.0181 (0.0448) |
0.039 (0.0823) |
0.0088 (0.0264) |
0.00056 (0.00332) |
0.00331 (0.0128) |
0.00084 (0.00471) |
0.00017 (0.00128) |
0.00173 (0.00837) |
0.00452 (0.0162) |
| xq gain | 22 (15%) | 128 |
0.00196 (0.00912) |
0.018 (0.0448) |
0.0212 (0.0511) |
0.0143 (0.0373) |
0.00077 (0.00442) |
0.00397 (0.0148) |
0.00282 (0.0115) |
0.00041 (0.00257) |
0.00144 (0.0071) |
0.0041 (0.0151) |
| 10p loss | 77 (51%) | 73 |
0.0207 (0.0499) |
0.00037 (0.00242) |
0.0083 (0.0258) |
0.00682 (0.0225) |
0.0003 (0.00206) |
0.0055 (0.019) |
0.0382 (0.0814) |
0.00085 (0.00473) |
0.00209 (0.00955) |
0.00127 (0.00648) |
| 15q loss | 29 (19%) | 121 |
0.00548 (0.019) |
3e-05 (0.000288) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
| 19p loss | 50 (33%) | 100 |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
| 19q loss | 53 (35%) | 97 |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
| 22q loss | 45 (30%) | 105 |
0.00234 (0.0101) |
1e-05 (0.000121) |
0.00022 (0.00161) |
2e-05 (0.000203) |
1e-05 (0.000121) |
1e-05 (0.000121) |
2e-05 (0.000203) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
| 7p gain | 121 (81%) | 29 |
0.00459 (0.0163) |
0.058 (0.11) |
0.0153 (0.0394) |
0.0206 (0.0498) |
0.0045 (0.0162) |
0.0088 (0.0264) |
0.00746 (0.0236) |
0.00733 (0.0235) |
0.00727 (0.0234) |
0.0229 (0.054) |
| 8p gain | 110 (73%) | 40 |
0.0627 (0.117) |
0.0059 (0.02) |
0.00106 (0.00573) |
0.00014 (0.00109) |
1e-05 (0.000121) |
0.0003 (0.00206) |
4e-05 (0.000375) |
2e-05 (0.000203) |
2e-05 (0.000203) |
6e-05 (0.000522) |
| 15q gain | 51 (34%) | 99 |
0.0513 (0.102) |
0.00227 (0.01) |
0.0019 (0.0089) |
0.0003 (0.00206) |
1e-05 (0.000121) |
2e-05 (0.000203) |
8e-05 (0.00068) |
1e-05 (0.000121) |
1e-05 (0.000121) |
1e-05 (0.000121) |
| 19q gain | 29 (19%) | 121 |
0.0161 (0.0407) |
8e-05 (0.00068) |
0.00215 (0.00976) |
0.0026 (0.0108) |
4e-05 (0.000375) |
0.00062 (0.00358) |
0.146 (0.223) |
6e-05 (0.000522) |
0.00033 (0.00222) |
1e-05 (0.000121) |
| 22q gain | 38 (25%) | 112 |
2e-05 (0.000203) |
0.00134 (0.00675) |
0.00924 (0.0275) |
0.00051 (0.00309) |
3e-05 (0.000288) |
1e-05 (0.000121) |
0.0558 (0.107) |
2e-05 (0.000203) |
6e-05 (0.000522) |
1e-05 (0.000121) |
| 17p loss | 37 (25%) | 113 |
2e-05 (0.000203) |
0.0405 (0.0844) |
0.0443 (0.0906) |
0.00321 (0.0125) |
0.00462 (0.0164) |
0.00024 (0.00174) |
0.0568 (0.109) |
0.00314 (0.0125) |
0.00168 (0.00818) |
2e-05 (0.000203) |
| 3p gain | 27 (18%) | 123 |
0.0221 (0.0524) |
0.398 (0.484) |
0.00179 (0.00849) |
0.0137 (0.0367) |
0.00691 (0.0226) |
0.00628 (0.0209) |
0.0811 (0.141) |
0.013 (0.0351) |
0.0153 (0.0394) |
0.0102 (0.0297) |
| 5p gain | 6 (4%) | 144 |
0.668 (0.733) |
0.0262 (0.0603) |
0.00854 (0.0261) |
0.151 (0.227) |
0.0115 (0.0323) |
0.00815 (0.0256) |
0.00423 (0.0154) |
0.00637 (0.0211) |
0.00358 (0.0134) |
0.00568 (0.0195) |
| 16p gain | 16 (11%) | 134 |
0.0116 (0.0324) |
0.0794 (0.139) |
0.0941 (0.158) |
0.00269 (0.0111) |
0.00411 (0.0151) |
0.0178 (0.0445) |
0.00228 (0.01) |
0.00609 (0.0205) |
0.00298 (0.012) |
0.0217 (0.0518) |
| 20q gain | 40 (27%) | 110 |
0.00741 (0.0235) |
0.00569 (0.0195) |
0.0871 (0.148) |
0.0366 (0.0783) |
0.00715 (0.0232) |
0.0537 (0.104) |
0.0472 (0.0947) |
0.0126 (0.0344) |
0.0164 (0.0413) |
0.0144 (0.0376) |
| 3p loss | 30 (20%) | 120 |
0.934 (0.955) |
0.0306 (0.0684) |
0.0162 (0.0409) |
0.318 (0.411) |
0.00121 (0.00635) |
0.00317 (0.0125) |
0.00122 (0.00636) |
0.00078 (0.00444) |
0.00241 (0.0103) |
0.00168 (0.00818) |
| 8p loss | 12 (8%) | 138 |
0.355 (0.445) |
0.0508 (0.101) |
0.0274 (0.0622) |
0.00944 (0.0278) |
0.0103 (0.0297) |
0.047 (0.0947) |
0.00853 (0.0261) |
0.00207 (0.00951) |
0.0074 (0.0235) |
0.0226 (0.0535) |
| 8q loss | 5 (3%) | 145 |
0.188 (0.268) |
0.0242 (0.0565) |
0.121 (0.191) |
0.0143 (0.0373) |
0.00237 (0.0102) |
0.0121 (0.0335) |
0.00132 (0.00669) |
0.00226 (0.01) |
0.0029 (0.0117) |
0.00335 (0.0128) |
| 10q loss | 72 (48%) | 78 |
0.00878 (0.0264) |
1e-05 (0.000121) |
0.133 (0.206) |
0.0767 (0.136) |
0.00018 (0.00135) |
0.00229 (0.01) |
0.0322 (0.0706) |
0.00041 (0.00257) |
0.00123 (0.00636) |
0.00139 (0.00695) |
| 14q loss | 20 (13%) | 130 |
0.119 (0.191) |
0.00079 (0.00446) |
0.0277 (0.0626) |
0.0937 (0.158) |
0.0043 (0.0156) |
5e-05 (0.000457) |
0.0308 (0.0684) |
0.00322 (0.0125) |
0.00247 (0.0104) |
0.0109 (0.0311) |
| 3q gain | 36 (24%) | 114 |
0.00683 (0.0225) |
0.179 (0.257) |
0.00227 (0.01) |
0.00327 (0.0127) |
0.0321 (0.0706) |
0.0327 (0.0712) |
0.0804 (0.14) |
0.0216 (0.0518) |
0.0386 (0.082) |
0.0767 (0.136) |
| 6p gain | 28 (19%) | 122 |
0.00042 (0.00261) |
0.753 (0.806) |
0.425 (0.511) |
0.0413 (0.0856) |
0.0124 (0.0342) |
0.00098 (0.00537) |
0.0168 (0.0419) |
0.00612 (0.0205) |
0.0541 (0.105) |
0.0197 (0.0484) |
| 16q gain | 14 (9%) | 136 |
0.00719 (0.0232) |
0.14 (0.215) |
0.0859 (0.147) |
0.00858 (0.0261) |
0.00925 (0.0275) |
0.0486 (0.0969) |
0.0135 (0.0363) |
0.0125 (0.0343) |
0.00819 (0.0256) |
0.052 (0.102) |
| 4q loss | 108 (72%) | 42 |
0.067 (0.123) |
0.0103 (0.0297) |
0.485 (0.57) |
0.55 (0.63) |
0.0108 (0.0308) |
0.0118 (0.033) |
0.0157 (0.0401) |
0.00502 (0.0176) |
0.0352 (0.0762) |
0.0257 (0.0594) |
| 11p loss | 98 (65%) | 52 |
0.00854 (0.0261) |
0.184 (0.265) |
0.0772 (0.137) |
0.164 (0.241) |
0.00039 (0.00253) |
0.00055 (0.00328) |
0.00103 (0.0056) |
0.00041 (0.00257) |
0.00178 (0.00849) |
0.00125 (0.00642) |
| 11q loss | 115 (77%) | 35 |
1e-05 (0.000121) |
0.123 (0.194) |
0.112 (0.182) |
0.0551 (0.106) |
9e-05 (0.000757) |
2e-05 (0.000203) |
0.00062 (0.00358) |
0.00014 (0.00109) |
0.00108 (0.00579) |
2e-05 (0.000203) |
| 2p gain | 46 (31%) | 104 |
0.0138 (0.0367) |
0.00878 (0.0264) |
0.0689 (0.125) |
0.0385 (0.0818) |
0.0163 (0.0411) |
0.169 (0.247) |
0.0594 (0.112) |
0.0243 (0.0565) |
0.0301 (0.0674) |
0.0629 (0.117) |
| 6q gain | 23 (15%) | 127 |
0.0231 (0.0541) |
0.88 (0.909) |
0.838 (0.876) |
0.215 (0.298) |
0.0138 (0.0367) |
0.00029 (0.00204) |
0.0125 (0.0343) |
0.00419 (0.0153) |
0.0508 (0.101) |
0.03 (0.0674) |
| 7q gain | 105 (70%) | 45 |
0.549 (0.629) |
0.0683 (0.125) |
0.105 (0.172) |
0.438 (0.522) |
0.00437 (0.0158) |
0.0117 (0.0327) |
0.00255 (0.0107) |
0.00257 (0.0107) |
0.00202 (0.00934) |
0.00338 (0.0128) |
| 5q loss | 101 (67%) | 49 |
0.0584 (0.11) |
0.0618 (0.116) |
0.0404 (0.0844) |
0.26 (0.35) |
0.0137 (0.0366) |
0.00338 (0.0128) |
0.306 (0.399) |
0.0103 (0.0297) |
0.02 (0.0489) |
0.00802 (0.0253) |
| 13q loss | 113 (75%) | 37 |
0.0442 (0.0906) |
0.29 (0.382) |
0.094 (0.158) |
0.0524 (0.103) |
0.0327 (0.0712) |
0.00111 (0.00591) |
0.0451 (0.0918) |
0.0231 (0.0541) |
0.0996 (0.165) |
0.0014 (0.00695) |
| 17q loss | 16 (11%) | 134 |
0.00581 (0.0198) |
0.131 (0.205) |
0.436 (0.522) |
0.0633 (0.117) |
0.0198 (0.0485) |
0.029 (0.0654) |
0.0684 (0.125) |
0.0146 (0.0379) |
0.0107 (0.0307) |
0.00489 (0.0172) |
| 5q gain | 3 (2%) | 147 |
0.777 (0.827) |
0.0574 (0.109) |
0.0358 (0.0771) |
0.0411 (0.0855) |
0.111 (0.18) |
0.015 (0.0388) |
0.0134 (0.0361) |
0.0392 (0.0823) |
||
| 6q loss | 16 (11%) | 134 |
0.12 (0.191) |
0.00963 (0.0283) |
0.158 (0.234) |
0.061 (0.114) |
0.0444 (0.0906) |
0.00117 (0.00618) |
0.107 (0.175) |
0.0273 (0.0622) |
0.0354 (0.0764) |
0.0993 (0.165) |
| xq loss | 29 (19%) | 121 |
0.00019 (0.00141) |
0.00187 (0.00881) |
0.155 (0.232) |
0.62 (0.693) |
0.162 (0.239) |
0.0984 (0.164) |
0.0254 (0.0589) |
0.0266 (0.0611) |
0.0527 (0.103) |
0.00393 (0.0147) |
| 16p loss | 44 (29%) | 106 |
0.148 (0.224) |
0.00599 (0.0202) |
0.29 (0.382) |
0.252 (0.341) |
0.0804 (0.14) |
0.263 (0.354) |
0.00855 (0.0261) |
0.0112 (0.0316) |
0.0786 (0.138) |
0.21 (0.292) |
| xp loss | 29 (19%) | 121 |
0.00234 (0.0101) |
0.00175 (0.00841) |
0.761 (0.813) |
0.918 (0.939) |
0.162 (0.239) |
0.178 (0.257) |
0.074 (0.133) |
0.0926 (0.156) |
0.0536 (0.104) |
0.00352 (0.0133) |
| 11q gain | 4 (3%) | 146 |
0.389 (0.475) |
0.149 (0.225) |
0.0399 (0.0837) |
0.148 (0.224) |
0.0784 (0.138) |
0.0142 (0.0373) |
0.38 (0.468) |
0.108 (0.177) |
0.106 (0.174) |
0.337 (0.427) |
| 12q gain | 100 (67%) | 50 |
0.569 (0.648) |
0.842 (0.879) |
0.264 (0.354) |
0.548 (0.629) |
0.205 (0.287) |
0.339 (0.428) |
0.0479 (0.0959) |
0.176 (0.256) |
0.0757 (0.135) |
0.00716 (0.0232) |
| 20p gain | 34 (23%) | 116 |
0.00525 (0.0183) |
0.115 (0.184) |
0.297 (0.388) |
0.171 (0.25) |
0.0415 (0.0859) |
0.285 (0.377) |
0.146 (0.223) |
0.148 (0.224) |
0.0604 (0.113) |
0.0637 (0.118) |
| 3q loss | 22 (15%) | 128 |
0.738 (0.792) |
0.74 (0.793) |
0.047 (0.0947) |
0.152 (0.227) |
0.0867 (0.148) |
0.0573 (0.109) |
0.0717 (0.129) |
0.0725 (0.131) |
0.0472 (0.0947) |
0.126 (0.198) |
| 4p loss | 92 (61%) | 58 |
0.629 (0.701) |
0.0454 (0.0921) |
0.365 (0.455) |
0.782 (0.831) |
0.0322 (0.0706) |
0.165 (0.242) |
0.102 (0.169) |
0.0789 (0.139) |
0.113 (0.183) |
0.333 (0.424) |
| 6p loss | 13 (9%) | 137 |
0.268 (0.359) |
0.0361 (0.0774) |
0.311 (0.403) |
0.0828 (0.143) |
0.162 (0.239) |
0.0142 (0.0373) |
0.269 (0.36) |
0.114 (0.184) |
0.185 (0.265) |
0.321 (0.414) |
| 9q loss | 58 (39%) | 92 |
0.00028 (0.00199) |
0.336 (0.427) |
0.145 (0.221) |
0.176 (0.256) |
0.308 (0.401) |
0.0185 (0.0456) |
0.657 (0.724) |
0.397 (0.484) |
0.364 (0.455) |
0.524 (0.607) |
| 18p loss | 116 (77%) | 34 |
0.692 (0.748) |
0.075 (0.134) |
0.7 (0.754) |
0.854 (0.89) |
0.0432 (0.089) |
0.243 (0.33) |
0.0888 (0.151) |
0.016 (0.0407) |
0.278 (0.368) |
0.135 (0.209) |
| 18q loss | 122 (81%) | 28 |
0.086 (0.147) |
0.315 (0.408) |
0.506 (0.589) |
0.874 (0.904) |
0.0689 (0.125) |
0.126 (0.198) |
0.0643 (0.119) |
0.032 (0.0706) |
0.201 (0.283) |
0.0205 (0.0498) |
| 20p loss | 30 (20%) | 120 |
0.236 (0.322) |
0.188 (0.268) |
0.228 (0.314) |
0.426 (0.511) |
0.198 (0.28) |
0.172 (0.25) |
0.0157 (0.0401) |
0.15 (0.226) |
0.08 (0.14) |
0.0274 (0.0622) |
| 1q gain | 61 (41%) | 89 |
0.439 (0.523) |
0.663 (0.729) |
0.2 (0.281) |
0.459 (0.544) |
0.826 (0.867) |
0.0595 (0.112) |
0.0391 (0.0823) |
0.635 (0.706) |
0.242 (0.329) |
0.0534 (0.104) |
| 2q gain | 42 (28%) | 108 |
0.116 (0.186) |
0.0331 (0.0717) |
0.881 (0.909) |
0.346 (0.435) |
0.278 (0.368) |
0.749 (0.802) |
0.491 (0.575) |
0.4 (0.486) |
0.345 (0.435) |
0.415 (0.5) |
| 1p loss | 18 (12%) | 132 |
0.121 (0.191) |
0.572 (0.649) |
0.488 (0.573) |
0.412 (0.498) |
0.649 (0.718) |
0.885 (0.912) |
0.0219 (0.052) |
0.357 (0.447) |
0.132 (0.205) |
0.369 (0.457) |
| 5p loss | 103 (69%) | 47 |
0.115 (0.184) |
0.211 (0.294) |
0.0273 (0.0622) |
0.478 (0.566) |
0.116 (0.185) |
0.133 (0.206) |
0.49 (0.574) |
0.0835 (0.144) |
0.112 (0.182) |
0.105 (0.173) |
| 9p loss | 63 (42%) | 87 |
0.0323 (0.0706) |
1 (1.00) |
0.627 (0.7) |
0.308 (0.401) |
0.868 (0.899) |
0.438 (0.522) |
0.783 (0.831) |
0.771 (0.822) |
0.911 (0.934) |
0.8 (0.847) |
| 16q loss | 51 (34%) | 99 |
0.0795 (0.139) |
0.0665 (0.122) |
0.658 (0.724) |
0.591 (0.664) |
0.233 (0.32) |
0.483 (0.569) |
0.0307 (0.0684) |
0.121 (0.191) |
0.329 (0.421) |
0.691 (0.748) |
| 4p gain | 3 (2%) | 147 |
0.636 (0.706) |
0.199 (0.281) |
0.862 (0.895) |
1 (1.00) |
1 (1.00) |
0.684 (0.745) |
0.493 (0.576) |
1 (1.00) |
1 (1.00) |
0.893 (0.919) |
| 9p gain | 16 (11%) | 134 |
0.235 (0.322) |
0.333 (0.424) |
0.432 (0.518) |
0.696 (0.751) |
0.157 (0.234) |
0.293 (0.385) |
0.22 (0.304) |
0.139 (0.215) |
0.178 (0.257) |
0.329 (0.421) |
| 9q gain | 17 (11%) | 133 |
0.152 (0.227) |
0.497 (0.579) |
0.803 (0.849) |
0.535 (0.619) |
1 (1.00) |
0.0776 (0.137) |
0.442 (0.526) |
0.895 (0.92) |
0.542 (0.625) |
0.382 (0.469) |
| 10p gain | 6 (4%) | 144 |
0.585 (0.661) |
0.0952 (0.159) |
0.642 (0.711) |
0.827 (0.867) |
0.324 (0.416) |
0.343 (0.434) |
0.151 (0.227) |
0.324 (0.416) |
0.368 (0.457) |
0.0568 (0.109) |
| 10q gain | 8 (5%) | 142 |
0.596 (0.669) |
0.388 (0.474) |
0.546 (0.628) |
0.179 (0.257) |
0.367 (0.456) |
0.227 (0.313) |
0.0545 (0.105) |
0.411 (0.497) |
0.515 (0.598) |
0.143 (0.22) |
| 11p gain | 10 (7%) | 140 |
0.272 (0.363) |
0.187 (0.267) |
0.09 (0.152) |
0.13 (0.204) |
0.164 (0.241) |
0.0519 (0.102) |
0.197 (0.28) |
0.2 (0.282) |
0.203 (0.284) |
0.356 (0.446) |
| 12p gain | 146 (97%) | 4 |
0.194 (0.276) |
0.384 (0.471) |
0.519 (0.602) |
0.537 (0.62) |
0.81 (0.855) |
0.37 (0.458) |
0.316 (0.409) |
0.583 (0.66) |
0.693 (0.748) |
0.087 (0.148) |
| 14q gain | 51 (34%) | 99 |
0.253 (0.341) |
0.237 (0.324) |
0.588 (0.662) |
0.568 (0.648) |
0.584 (0.66) |
0.398 (0.484) |
0.822 (0.864) |
0.303 (0.396) |
0.202 (0.283) |
0.482 (0.568) |
| 18p gain | 4 (3%) | 146 |
0.687 (0.746) |
0.0699 (0.127) |
0.69 (0.748) |
1 (1.00) |
0.379 (0.467) |
0.785 (0.833) |
0.675 (0.739) |
0.479 (0.566) |
0.572 (0.649) |
0.683 (0.745) |
| 21q gain | 125 (83%) | 25 |
0.405 (0.491) |
0.274 (0.365) |
0.103 (0.17) |
0.333 (0.424) |
0.0824 (0.143) |
0.238 (0.324) |
0.217 (0.301) |
0.0894 (0.151) |
0.128 (0.2) |
0.131 (0.205) |
| 1q loss | 8 (5%) | 142 |
0.346 (0.435) |
0.244 (0.331) |
0.817 (0.86) |
0.682 (0.745) |
0.293 (0.385) |
0.217 (0.301) |
0.382 (0.469) |
0.324 (0.416) |
0.157 (0.234) |
0.596 (0.669) |
| 2p loss | 5 (3%) | 145 |
0.86 (0.895) |
0.378 (0.467) |
1 (1.00) |
1 (1.00) |
0.735 (0.791) |
1 (1.00) |
1 (1.00) |
0.813 (0.857) |
||
| 2q loss | 6 (4%) | 144 |
0.445 (0.528) |
0.676 (0.739) |
0.862 (0.895) |
0.602 (0.674) |
0.557 (0.637) |
0.9 (0.924) |
0.666 (0.731) |
0.657 (0.724) |
0.564 (0.644) |
1 (1.00) |
| 20q loss | 15 (10%) | 135 |
0.586 (0.661) |
0.489 (0.574) |
0.638 (0.708) |
0.832 (0.871) |
0.2 (0.281) |
0.273 (0.363) |
0.0697 (0.126) |
0.141 (0.217) |
0.101 (0.168) |
0.25 (0.338) |
P value = 0.00282 (Fisher's exact test), Q value = 0.011
Table S1. Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 1P GAIN MUTATED | 9 | 5 | 23 |
| 1P GAIN WILD-TYPE | 39 | 39 | 35 |
Figure S1. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 5e-04 (Fisher's exact test), Q value = 0.0031
Table S2. Gene #1: '1p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 1P GAIN MUTATED | 8 | 22 | 7 |
| 1P GAIN WILD-TYPE | 48 | 27 | 38 |
Figure S2. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00317 (Fisher's exact test), Q value = 0.013
Table S3. Gene #1: '1p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 1P GAIN MUTATED | 6 | 2 | 4 | 9 | 11 |
| 1P GAIN WILD-TYPE | 39 | 6 | 6 | 28 | 7 |
Figure S3. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.011 (Fisher's exact test), Q value = 0.031
Table S4. Gene #1: '1p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 1P GAIN MUTATED | 7 | 8 | 17 |
| 1P GAIN WILD-TYPE | 44 | 17 | 25 |
Figure S4. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00035 (Fisher's exact test), Q value = 0.0023
Table S5. Gene #1: '1p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 1P GAIN MUTATED | 9 | 19 | 9 |
| 1P GAIN WILD-TYPE | 61 | 21 | 31 |
Figure S5. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00221 (Fisher's exact test), Q value = 0.01
Table S6. Gene #1: '1p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 1P GAIN MUTATED | 6 | 3 | 3 | 8 | 4 | 12 | 1 |
| 1P GAIN WILD-TYPE | 37 | 24 | 9 | 16 | 4 | 11 | 12 |
Figure S6. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00016 (Fisher's exact test), Q value = 0.0012
Table S7. Gene #1: '1p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 1P GAIN MUTATED | 4 | 24 | 9 |
| 1P GAIN WILD-TYPE | 48 | 33 | 32 |
Figure S7. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.00095
Table S8. Gene #1: '1p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 1P GAIN MUTATED | 9 | 19 | 9 |
| 1P GAIN WILD-TYPE | 61 | 19 | 33 |
Figure S8. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S9. Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 1P GAIN MUTATED | 8 | 20 | 9 |
| 1P GAIN WILD-TYPE | 61 | 16 | 36 |
Figure S9. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00052 (Fisher's exact test), Q value = 0.0031
Table S10. Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 1P GAIN MUTATED | 5 | 4 | 19 | 9 |
| 1P GAIN WILD-TYPE | 32 | 29 | 19 | 33 |
Figure S10. Get High-res Image Gene #1: '1p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0391 (Fisher's exact test), Q value = 0.082
Table S11. Gene #2: '1q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 1Q GAIN MUTATED | 15 | 30 | 16 |
| 1Q GAIN WILD-TYPE | 37 | 27 | 25 |
Figure S11. Get High-res Image Gene #2: '1q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0138 (Fisher's exact test), Q value = 0.037
Table S12. Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 2P GAIN MUTATED | 10 | 10 | 26 |
| 2P GAIN WILD-TYPE | 38 | 34 | 32 |
Figure S12. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00878 (Fisher's exact test), Q value = 0.026
Table S13. Gene #3: '2p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 2P GAIN MUTATED | 9 | 18 | 19 |
| 2P GAIN WILD-TYPE | 47 | 31 | 26 |
Figure S13. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0385 (Fisher's exact test), Q value = 0.082
Table S14. Gene #3: '2p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 2P GAIN MUTATED | 9 | 10 | 16 |
| 2P GAIN WILD-TYPE | 42 | 15 | 26 |
Figure S14. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0163 (Fisher's exact test), Q value = 0.041
Table S15. Gene #3: '2p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 2P GAIN MUTATED | 14 | 14 | 18 |
| 2P GAIN WILD-TYPE | 56 | 26 | 22 |
Figure S15. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0243 (Fisher's exact test), Q value = 0.057
Table S16. Gene #3: '2p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 2P GAIN MUTATED | 14 | 14 | 18 |
| 2P GAIN WILD-TYPE | 56 | 24 | 24 |
Figure S16. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0301 (Fisher's exact test), Q value = 0.067
Table S17. Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 2P GAIN MUTATED | 14 | 13 | 19 |
| 2P GAIN WILD-TYPE | 55 | 23 | 26 |
Figure S17. Get High-res Image Gene #3: '2p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0331 (Fisher's exact test), Q value = 0.072
Table S18. Gene #4: '2q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 2Q GAIN MUTATED | 9 | 16 | 17 |
| 2Q GAIN WILD-TYPE | 47 | 33 | 28 |
Figure S18. Get High-res Image Gene #4: '2q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0221 (Fisher's exact test), Q value = 0.052
Table S19. Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 3P GAIN MUTATED | 5 | 5 | 17 |
| 3P GAIN WILD-TYPE | 43 | 39 | 41 |
Figure S19. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00179 (Fisher's exact test), Q value = 0.0085
Table S20. Gene #5: '3p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 3P GAIN MUTATED | 3 | 0 | 0 | 14 | 3 |
| 3P GAIN WILD-TYPE | 42 | 8 | 10 | 23 | 15 |
Figure S20. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.037
Table S21. Gene #5: '3p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 3P GAIN MUTATED | 3 | 7 | 10 |
| 3P GAIN WILD-TYPE | 48 | 18 | 32 |
Figure S21. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00691 (Fisher's exact test), Q value = 0.023
Table S22. Gene #5: '3p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 3P GAIN MUTATED | 6 | 8 | 13 |
| 3P GAIN WILD-TYPE | 64 | 32 | 27 |
Figure S22. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00628 (Fisher's exact test), Q value = 0.021
Table S23. Gene #5: '3p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 3P GAIN MUTATED | 4 | 2 | 3 | 5 | 3 | 3 | 7 |
| 3P GAIN WILD-TYPE | 39 | 25 | 9 | 19 | 5 | 20 | 6 |
Figure S23. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.013 (Fisher's exact test), Q value = 0.035
Table S24. Gene #5: '3p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 3P GAIN MUTATED | 6 | 9 | 12 |
| 3P GAIN WILD-TYPE | 64 | 29 | 30 |
Figure S24. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0153 (Fisher's exact test), Q value = 0.039
Table S25. Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3P GAIN MUTATED | 6 | 8 | 13 |
| 3P GAIN WILD-TYPE | 63 | 28 | 32 |
Figure S25. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0102 (Fisher's exact test), Q value = 0.03
Table S26. Gene #5: '3p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 3P GAIN MUTATED | 5 | 1 | 8 | 13 |
| 3P GAIN WILD-TYPE | 32 | 32 | 30 | 29 |
Figure S26. Get High-res Image Gene #5: '3p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00683 (Fisher's exact test), Q value = 0.022
Table S27. Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 3Q GAIN MUTATED | 5 | 10 | 21 |
| 3Q GAIN WILD-TYPE | 43 | 34 | 37 |
Figure S27. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00227 (Fisher's exact test), Q value = 0.01
Table S28. Gene #6: '3q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 3Q GAIN MUTATED | 4 | 0 | 2 | 16 | 4 |
| 3Q GAIN WILD-TYPE | 41 | 8 | 8 | 21 | 14 |
Figure S28. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00327 (Fisher's exact test), Q value = 0.013
Table S29. Gene #6: '3q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 3Q GAIN MUTATED | 4 | 9 | 13 |
| 3Q GAIN WILD-TYPE | 47 | 16 | 29 |
Figure S29. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0321 (Fisher's exact test), Q value = 0.071
Table S30. Gene #6: '3q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 3Q GAIN MUTATED | 10 | 13 | 13 |
| 3Q GAIN WILD-TYPE | 60 | 27 | 27 |
Figure S30. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0327 (Fisher's exact test), Q value = 0.071
Table S31. Gene #6: '3q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 3Q GAIN MUTATED | 5 | 5 | 5 | 5 | 3 | 6 | 7 |
| 3Q GAIN WILD-TYPE | 38 | 22 | 7 | 19 | 5 | 17 | 6 |
Figure S31. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0216 (Fisher's exact test), Q value = 0.052
Table S32. Gene #6: '3q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 3Q GAIN MUTATED | 10 | 14 | 12 |
| 3Q GAIN WILD-TYPE | 60 | 24 | 30 |
Figure S32. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0386 (Fisher's exact test), Q value = 0.082
Table S33. Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3Q GAIN MUTATED | 10 | 12 | 14 |
| 3Q GAIN WILD-TYPE | 59 | 24 | 31 |
Figure S33. Get High-res Image Gene #6: '3q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0262 (Fisher's exact test), Q value = 0.06
Table S34. Gene #8: '5p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 55 | 44 | 45 |
Figure S34. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00854 (Fisher's exact test), Q value = 0.026
Table S35. Gene #8: '5p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 5P GAIN MUTATED | 1 | 0 | 0 | 0 | 4 |
| 5P GAIN WILD-TYPE | 44 | 8 | 10 | 37 | 14 |
Figure S35. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0115 (Fisher's exact test), Q value = 0.032
Table S36. Gene #8: '5p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 69 | 35 | 40 |
Figure S36. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00815 (Fisher's exact test), Q value = 0.026
Table S37. Gene #8: '5p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 5P GAIN MUTATED | 0 | 1 | 0 | 0 | 2 | 3 | 0 |
| 5P GAIN WILD-TYPE | 43 | 26 | 12 | 24 | 6 | 20 | 13 |
Figure S37. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00423 (Fisher's exact test), Q value = 0.015
Table S38. Gene #8: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 5P GAIN MUTATED | 0 | 6 | 0 |
| 5P GAIN WILD-TYPE | 52 | 51 | 41 |
Figure S38. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00637 (Fisher's exact test), Q value = 0.021
Table S39. Gene #8: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 69 | 33 | 42 |
Figure S39. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00358 (Fisher's exact test), Q value = 0.013
Table S40. Gene #8: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 5P GAIN MUTATED | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 68 | 31 | 45 |
Figure S40. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00568 (Fisher's exact test), Q value = 0.019
Table S41. Gene #8: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 5P GAIN MUTATED | 0 | 1 | 5 | 0 |
| 5P GAIN WILD-TYPE | 37 | 32 | 33 | 42 |
Figure S41. Get High-res Image Gene #8: '5p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0358 (Fisher's exact test), Q value = 0.077
Table S42. Gene #9: '5q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 5Q GAIN MUTATED | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 70 | 37 | 40 |
Figure S42. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0411 (Fisher's exact test), Q value = 0.085
Table S43. Gene #9: '5q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 5Q GAIN MUTATED | 0 | 0 | 0 | 0 | 1 | 2 | 0 |
| 5Q GAIN WILD-TYPE | 43 | 27 | 12 | 24 | 7 | 21 | 13 |
Figure S43. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.015 (Fisher's exact test), Q value = 0.039
Table S44. Gene #9: '5q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 5Q GAIN MUTATED | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 70 | 35 | 42 |
Figure S44. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0134 (Fisher's exact test), Q value = 0.036
Table S45. Gene #9: '5q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 5Q GAIN MUTATED | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 69 | 33 | 45 |
Figure S45. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0392 (Fisher's exact test), Q value = 0.082
Table S46. Gene #9: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 5Q GAIN MUTATED | 0 | 0 | 3 | 0 |
| 5Q GAIN WILD-TYPE | 37 | 33 | 35 | 42 |
Figure S46. Get High-res Image Gene #9: '5q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00042 (Fisher's exact test), Q value = 0.0026
Table S47. Gene #10: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 6P GAIN MUTATED | 9 | 1 | 18 |
| 6P GAIN WILD-TYPE | 39 | 43 | 40 |
Figure S47. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0413 (Fisher's exact test), Q value = 0.086
Table S48. Gene #10: '6p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 6P GAIN MUTATED | 6 | 9 | 6 |
| 6P GAIN WILD-TYPE | 45 | 16 | 36 |
Figure S48. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0124 (Fisher's exact test), Q value = 0.034
Table S49. Gene #10: '6p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 6P GAIN MUTATED | 9 | 5 | 14 |
| 6P GAIN WILD-TYPE | 61 | 35 | 26 |
Figure S49. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00098 (Fisher's exact test), Q value = 0.0054
Table S50. Gene #10: '6p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6P GAIN MUTATED | 8 | 1 | 0 | 12 | 0 | 5 | 2 |
| 6P GAIN WILD-TYPE | 35 | 26 | 12 | 12 | 8 | 18 | 11 |
Figure S50. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0168 (Fisher's exact test), Q value = 0.042
Table S51. Gene #10: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 6P GAIN MUTATED | 7 | 7 | 14 |
| 6P GAIN WILD-TYPE | 45 | 50 | 27 |
Figure S51. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00612 (Fisher's exact test), Q value = 0.02
Table S52. Gene #10: '6p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 6P GAIN MUTATED | 9 | 4 | 15 |
| 6P GAIN WILD-TYPE | 61 | 34 | 27 |
Figure S52. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0197 (Fisher's exact test), Q value = 0.048
Table S53. Gene #10: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 6P GAIN MUTATED | 7 | 2 | 5 | 14 |
| 6P GAIN WILD-TYPE | 30 | 31 | 33 | 28 |
Figure S53. Get High-res Image Gene #10: '6p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0231 (Fisher's exact test), Q value = 0.054
Table S54. Gene #11: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 6Q GAIN MUTATED | 7 | 2 | 14 |
| 6Q GAIN WILD-TYPE | 41 | 42 | 44 |
Figure S54. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0138 (Fisher's exact test), Q value = 0.037
Table S55. Gene #11: '6q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 6Q GAIN MUTATED | 8 | 3 | 12 |
| 6Q GAIN WILD-TYPE | 62 | 37 | 28 |
Figure S55. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00029 (Fisher's exact test), Q value = 0.002
Table S56. Gene #11: '6q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6Q GAIN MUTATED | 8 | 0 | 0 | 11 | 0 | 3 | 1 |
| 6Q GAIN WILD-TYPE | 35 | 27 | 12 | 13 | 8 | 20 | 12 |
Figure S56. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0125 (Fisher's exact test), Q value = 0.034
Table S57. Gene #11: '6q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 6Q GAIN MUTATED | 7 | 4 | 12 |
| 6Q GAIN WILD-TYPE | 45 | 53 | 29 |
Figure S57. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00419 (Fisher's exact test), Q value = 0.015
Table S58. Gene #11: '6q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 6Q GAIN MUTATED | 8 | 2 | 13 |
| 6Q GAIN WILD-TYPE | 62 | 36 | 29 |
Figure S58. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.03 (Fisher's exact test), Q value = 0.067
Table S59. Gene #11: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 6Q GAIN MUTATED | 6 | 2 | 3 | 12 |
| 6Q GAIN WILD-TYPE | 31 | 31 | 35 | 30 |
Figure S59. Get High-res Image Gene #11: '6q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00459 (Fisher's exact test), Q value = 0.016
Table S60. Gene #12: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 7P GAIN MUTATED | 34 | 42 | 45 |
| 7P GAIN WILD-TYPE | 14 | 2 | 13 |
Figure S60. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0153 (Fisher's exact test), Q value = 0.039
Table S61. Gene #12: '7p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 7P GAIN MUTATED | 39 | 8 | 5 | 25 | 16 |
| 7P GAIN WILD-TYPE | 6 | 0 | 5 | 12 | 2 |
Figure S61. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0206 (Fisher's exact test), Q value = 0.05
Table S62. Gene #12: '7p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 7P GAIN MUTATED | 45 | 15 | 33 |
| 7P GAIN WILD-TYPE | 6 | 10 | 9 |
Figure S62. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0045 (Fisher's exact test), Q value = 0.016
Table S63. Gene #12: '7p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 7P GAIN MUTATED | 62 | 34 | 25 |
| 7P GAIN WILD-TYPE | 8 | 6 | 15 |
Figure S63. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0088 (Fisher's exact test), Q value = 0.026
Table S64. Gene #12: '7p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 7P GAIN MUTATED | 38 | 24 | 7 | 16 | 6 | 22 | 8 |
| 7P GAIN WILD-TYPE | 5 | 3 | 5 | 8 | 2 | 1 | 5 |
Figure S64. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00746 (Fisher's exact test), Q value = 0.024
Table S65. Gene #12: '7p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 7P GAIN MUTATED | 45 | 50 | 26 |
| 7P GAIN WILD-TYPE | 7 | 7 | 15 |
Figure S65. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00733 (Fisher's exact test), Q value = 0.023
Table S66. Gene #12: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 7P GAIN MUTATED | 62 | 32 | 27 |
| 7P GAIN WILD-TYPE | 8 | 6 | 15 |
Figure S66. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00727 (Fisher's exact test), Q value = 0.023
Table S67. Gene #12: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 7P GAIN MUTATED | 61 | 31 | 29 |
| 7P GAIN WILD-TYPE | 8 | 5 | 16 |
Figure S67. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0229 (Fisher's exact test), Q value = 0.054
Table S68. Gene #12: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 7P GAIN MUTATED | 32 | 30 | 32 | 27 |
| 7P GAIN WILD-TYPE | 5 | 3 | 6 | 15 |
Figure S68. Get High-res Image Gene #12: '7p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00437 (Fisher's exact test), Q value = 0.016
Table S69. Gene #13: '7q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 7Q GAIN MUTATED | 52 | 33 | 20 |
| 7Q GAIN WILD-TYPE | 18 | 7 | 20 |
Figure S69. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0117 (Fisher's exact test), Q value = 0.033
Table S70. Gene #13: '7q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 7Q GAIN MUTATED | 36 | 16 | 8 | 11 | 6 | 20 | 8 |
| 7Q GAIN WILD-TYPE | 7 | 11 | 4 | 13 | 2 | 3 | 5 |
Figure S70. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00255 (Fisher's exact test), Q value = 0.011
Table S71. Gene #13: '7q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 7Q GAIN MUTATED | 39 | 46 | 20 |
| 7Q GAIN WILD-TYPE | 13 | 11 | 21 |
Figure S71. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00257 (Fisher's exact test), Q value = 0.011
Table S72. Gene #13: '7q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 7Q GAIN MUTATED | 52 | 32 | 21 |
| 7Q GAIN WILD-TYPE | 18 | 6 | 21 |
Figure S72. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00202 (Fisher's exact test), Q value = 0.0093
Table S73. Gene #13: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 7Q GAIN MUTATED | 51 | 31 | 23 |
| 7Q GAIN WILD-TYPE | 18 | 5 | 22 |
Figure S73. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00338 (Fisher's exact test), Q value = 0.013
Table S74. Gene #13: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 7Q GAIN MUTATED | 30 | 22 | 32 | 21 |
| 7Q GAIN WILD-TYPE | 7 | 11 | 6 | 21 |
Figure S74. Get High-res Image Gene #13: '7q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0059 (Fisher's exact test), Q value = 0.02
Table S75. Gene #14: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 8P GAIN MUTATED | 49 | 33 | 28 |
| 8P GAIN WILD-TYPE | 7 | 16 | 17 |
Figure S75. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00106 (Fisher's exact test), Q value = 0.0057
Table S76. Gene #14: '8p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 8P GAIN MUTATED | 41 | 6 | 4 | 22 | 12 |
| 8P GAIN WILD-TYPE | 4 | 2 | 6 | 15 | 6 |
Figure S76. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.0011
Table S77. Gene #14: '8p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 8P GAIN MUTATED | 46 | 12 | 27 |
| 8P GAIN WILD-TYPE | 5 | 13 | 15 |
Figure S77. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S78. Gene #14: '8p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8P GAIN MUTATED | 63 | 26 | 21 |
| 8P GAIN WILD-TYPE | 7 | 14 | 19 |
Figure S78. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0021
Table S79. Gene #14: '8p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8P GAIN MUTATED | 37 | 26 | 8 | 14 | 5 | 15 | 5 |
| 8P GAIN WILD-TYPE | 6 | 1 | 4 | 10 | 3 | 8 | 8 |
Figure S79. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00037
Table S80. Gene #14: '8p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8P GAIN MUTATED | 46 | 44 | 20 |
| 8P GAIN WILD-TYPE | 6 | 13 | 21 |
Figure S80. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S81. Gene #14: '8p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8P GAIN MUTATED | 63 | 26 | 21 |
| 8P GAIN WILD-TYPE | 7 | 12 | 21 |
Figure S81. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S82. Gene #14: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8P GAIN MUTATED | 62 | 24 | 24 |
| 8P GAIN WILD-TYPE | 7 | 12 | 21 |
Figure S82. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00052
Table S83. Gene #14: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8P GAIN MUTATED | 32 | 31 | 26 | 21 |
| 8P GAIN WILD-TYPE | 5 | 2 | 12 | 21 |
Figure S83. Get High-res Image Gene #14: '8p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0205 (Fisher's exact test), Q value = 0.05
Table S84. Gene #15: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 8Q GAIN MUTATED | 34 | 39 | 38 |
| 8Q GAIN WILD-TYPE | 14 | 5 | 20 |
Figure S84. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00271 (Fisher's exact test), Q value = 0.011
Table S85. Gene #15: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 8Q GAIN MUTATED | 49 | 36 | 26 |
| 8Q GAIN WILD-TYPE | 7 | 13 | 19 |
Figure S85. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0121 (Fisher's exact test), Q value = 0.033
Table S86. Gene #15: '8q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 8Q GAIN MUTATED | 40 | 6 | 6 | 21 | 13 |
| 8Q GAIN WILD-TYPE | 5 | 2 | 4 | 16 | 5 |
Figure S86. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00245 (Fisher's exact test), Q value = 0.01
Table S87. Gene #15: '8q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 8Q GAIN MUTATED | 45 | 14 | 27 |
| 8Q GAIN WILD-TYPE | 6 | 11 | 15 |
Figure S87. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00017 (Fisher's exact test), Q value = 0.0013
Table S88. Gene #15: '8q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8Q GAIN MUTATED | 62 | 28 | 21 |
| 8Q GAIN WILD-TYPE | 8 | 12 | 19 |
Figure S88. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00034 (Fisher's exact test), Q value = 0.0023
Table S89. Gene #15: '8q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8Q GAIN MUTATED | 40 | 22 | 8 | 15 | 5 | 17 | 4 |
| 8Q GAIN WILD-TYPE | 3 | 5 | 4 | 9 | 3 | 6 | 9 |
Figure S89. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00011 (Fisher's exact test), Q value = 0.00089
Table S90. Gene #15: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8Q GAIN MUTATED | 47 | 43 | 21 |
| 8Q GAIN WILD-TYPE | 5 | 14 | 20 |
Figure S90. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00012 (Fisher's exact test), Q value = 0.00095
Table S91. Gene #15: '8q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8Q GAIN MUTATED | 62 | 27 | 22 |
| 8Q GAIN WILD-TYPE | 8 | 11 | 20 |
Figure S91. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 4e-04 (Fisher's exact test), Q value = 0.0026
Table S92. Gene #15: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8Q GAIN MUTATED | 61 | 25 | 25 |
| 8Q GAIN WILD-TYPE | 8 | 11 | 20 |
Figure S92. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00031 (Fisher's exact test), Q value = 0.0021
Table S93. Gene #15: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8Q GAIN MUTATED | 34 | 28 | 27 | 22 |
| 8Q GAIN WILD-TYPE | 3 | 5 | 11 | 20 |
Figure S93. Get High-res Image Gene #15: '8q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0399 (Fisher's exact test), Q value = 0.084
Table S94. Gene #21: '11q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 11Q GAIN MUTATED | 0 | 0 | 0 | 1 | 3 |
| 11Q GAIN WILD-TYPE | 45 | 8 | 10 | 36 | 15 |
Figure S94. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0142 (Fisher's exact test), Q value = 0.037
Table S95. Gene #21: '11q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 11Q GAIN MUTATED | 0 | 0 | 0 | 0 | 1 | 1 | 2 |
| 11Q GAIN WILD-TYPE | 43 | 27 | 12 | 24 | 7 | 22 | 11 |
Figure S95. Get High-res Image Gene #21: '11q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0479 (Fisher's exact test), Q value = 0.096
Table S96. Gene #23: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 12Q GAIN MUTATED | 34 | 44 | 22 |
| 12Q GAIN WILD-TYPE | 18 | 13 | 19 |
Figure S96. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00716 (Fisher's exact test), Q value = 0.023
Table S97. Gene #23: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 12Q GAIN MUTATED | 21 | 29 | 27 | 23 |
| 12Q GAIN WILD-TYPE | 16 | 4 | 11 | 19 |
Figure S97. Get High-res Image Gene #23: '12q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00227 (Fisher's exact test), Q value = 0.01
Table S98. Gene #25: '15q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 15Q GAIN MUTATED | 29 | 11 | 11 |
| 15Q GAIN WILD-TYPE | 27 | 38 | 34 |
Figure S98. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0019 (Fisher's exact test), Q value = 0.0089
Table S99. Gene #25: '15q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 15Q GAIN MUTATED | 24 | 2 | 2 | 5 | 4 |
| 15Q GAIN WILD-TYPE | 21 | 6 | 8 | 32 | 14 |
Figure S99. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 3e-04 (Fisher's exact test), Q value = 0.0021
Table S100. Gene #25: '15q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 15Q GAIN MUTATED | 26 | 3 | 8 |
| 15Q GAIN WILD-TYPE | 25 | 22 | 34 |
Figure S100. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S101. Gene #25: '15q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 15Q GAIN MUTATED | 38 | 8 | 5 |
| 15Q GAIN WILD-TYPE | 32 | 32 | 35 |
Figure S101. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S102. Gene #25: '15q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 15Q GAIN MUTATED | 26 | 12 | 1 | 4 | 0 | 7 | 1 |
| 15Q GAIN WILD-TYPE | 17 | 15 | 11 | 20 | 8 | 16 | 12 |
Figure S102. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 8e-05 (Fisher's exact test), Q value = 0.00068
Table S103. Gene #25: '15q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 15Q GAIN MUTATED | 28 | 18 | 5 |
| 15Q GAIN WILD-TYPE | 24 | 39 | 36 |
Figure S103. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S104. Gene #25: '15q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 15Q GAIN MUTATED | 38 | 8 | 5 |
| 15Q GAIN WILD-TYPE | 32 | 30 | 37 |
Figure S104. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S105. Gene #25: '15q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 15Q GAIN MUTATED | 37 | 8 | 6 |
| 15Q GAIN WILD-TYPE | 32 | 28 | 39 |
Figure S105. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S106. Gene #25: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 15Q GAIN MUTATED | 22 | 16 | 8 | 5 |
| 15Q GAIN WILD-TYPE | 15 | 17 | 30 | 37 |
Figure S106. Get High-res Image Gene #25: '15q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0116 (Fisher's exact test), Q value = 0.032
Table S107. Gene #26: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 16P GAIN MUTATED | 2 | 2 | 12 |
| 16P GAIN WILD-TYPE | 46 | 42 | 46 |
Figure S107. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00269 (Fisher's exact test), Q value = 0.011
Table S108. Gene #26: '16p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 16P GAIN MUTATED | 2 | 8 | 4 |
| 16P GAIN WILD-TYPE | 49 | 17 | 38 |
Figure S108. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00411 (Fisher's exact test), Q value = 0.015
Table S109. Gene #26: '16p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 16P GAIN MUTATED | 3 | 3 | 10 |
| 16P GAIN WILD-TYPE | 67 | 37 | 30 |
Figure S109. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0178 (Fisher's exact test), Q value = 0.044
Table S110. Gene #26: '16p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 16P GAIN MUTATED | 2 | 1 | 1 | 8 | 0 | 2 | 2 |
| 16P GAIN WILD-TYPE | 41 | 26 | 11 | 16 | 8 | 21 | 11 |
Figure S110. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00228 (Fisher's exact test), Q value = 0.01
Table S111. Gene #26: '16p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16P GAIN MUTATED | 1 | 5 | 10 |
| 16P GAIN WILD-TYPE | 51 | 52 | 31 |
Figure S111. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00609 (Fisher's exact test), Q value = 0.02
Table S112. Gene #26: '16p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 16P GAIN MUTATED | 3 | 3 | 10 |
| 16P GAIN WILD-TYPE | 67 | 35 | 32 |
Figure S112. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00298 (Fisher's exact test), Q value = 0.012
Table S113. Gene #26: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 16P GAIN MUTATED | 3 | 2 | 11 |
| 16P GAIN WILD-TYPE | 66 | 34 | 34 |
Figure S113. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0217 (Fisher's exact test), Q value = 0.052
Table S114. Gene #26: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 16P GAIN MUTATED | 2 | 1 | 3 | 10 |
| 16P GAIN WILD-TYPE | 35 | 32 | 35 | 32 |
Figure S114. Get High-res Image Gene #26: '16p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00719 (Fisher's exact test), Q value = 0.023
Table S115. Gene #27: '16q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 16Q GAIN MUTATED | 2 | 1 | 11 |
| 16Q GAIN WILD-TYPE | 46 | 43 | 47 |
Figure S115. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00858 (Fisher's exact test), Q value = 0.026
Table S116. Gene #27: '16q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 16Q GAIN MUTATED | 1 | 6 | 4 |
| 16Q GAIN WILD-TYPE | 50 | 19 | 38 |
Figure S116. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00925 (Fisher's exact test), Q value = 0.027
Table S117. Gene #27: '16q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 16Q GAIN MUTATED | 2 | 4 | 8 |
| 16Q GAIN WILD-TYPE | 68 | 36 | 32 |
Figure S117. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0486 (Fisher's exact test), Q value = 0.097
Table S118. Gene #27: '16q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 16Q GAIN MUTATED | 1 | 1 | 1 | 6 | 0 | 3 | 2 |
| 16Q GAIN WILD-TYPE | 42 | 26 | 11 | 18 | 8 | 20 | 11 |
Figure S118. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0135 (Fisher's exact test), Q value = 0.036
Table S119. Gene #27: '16q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16Q GAIN MUTATED | 1 | 5 | 8 |
| 16Q GAIN WILD-TYPE | 51 | 52 | 33 |
Figure S119. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0125 (Fisher's exact test), Q value = 0.034
Table S120. Gene #27: '16q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 16Q GAIN MUTATED | 2 | 4 | 8 |
| 16Q GAIN WILD-TYPE | 68 | 34 | 34 |
Figure S120. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00819 (Fisher's exact test), Q value = 0.026
Table S121. Gene #27: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 16Q GAIN MUTATED | 2 | 3 | 9 |
| 16Q GAIN WILD-TYPE | 67 | 33 | 36 |
Figure S121. Get High-res Image Gene #27: '16q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S122. Gene #28: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17P GAIN MUTATED | 9 | 2 | 29 |
| 17P GAIN WILD-TYPE | 39 | 42 | 29 |
Figure S122. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S123. Gene #28: '17p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 17P GAIN MUTATED | 3 | 23 | 14 |
| 17P GAIN WILD-TYPE | 53 | 26 | 31 |
Figure S123. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00029
Table S124. Gene #28: '17p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 17P GAIN MUTATED | 2 | 0 | 5 | 15 | 8 |
| 17P GAIN WILD-TYPE | 43 | 8 | 5 | 22 | 10 |
Figure S124. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S125. Gene #28: '17p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 17P GAIN MUTATED | 2 | 11 | 17 |
| 17P GAIN WILD-TYPE | 49 | 14 | 25 |
Figure S125. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S126. Gene #28: '17p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17P GAIN MUTATED | 3 | 19 | 18 |
| 17P GAIN WILD-TYPE | 67 | 21 | 22 |
Figure S126. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S127. Gene #28: '17p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17P GAIN MUTATED | 2 | 1 | 5 | 11 | 4 | 12 | 5 |
| 17P GAIN WILD-TYPE | 41 | 26 | 7 | 13 | 4 | 11 | 8 |
Figure S127. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S128. Gene #28: '17p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 17P GAIN MUTATED | 2 | 21 | 17 |
| 17P GAIN WILD-TYPE | 50 | 36 | 24 |
Figure S128. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S129. Gene #28: '17p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17P GAIN MUTATED | 3 | 19 | 18 |
| 17P GAIN WILD-TYPE | 67 | 19 | 24 |
Figure S129. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S130. Gene #28: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17P GAIN MUTATED | 3 | 17 | 20 |
| 17P GAIN WILD-TYPE | 66 | 19 | 25 |
Figure S130. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S131. Gene #28: '17p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17P GAIN MUTATED | 1 | 2 | 20 | 17 |
| 17P GAIN WILD-TYPE | 36 | 31 | 18 | 25 |
Figure S131. Get High-res Image Gene #28: '17p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00025 (Fisher's exact test), Q value = 0.0018
Table S132. Gene #29: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17Q GAIN MUTATED | 13 | 7 | 31 |
| 17Q GAIN WILD-TYPE | 35 | 37 | 27 |
Figure S132. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 6e-05 (Fisher's exact test), Q value = 0.00052
Table S133. Gene #29: '17q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 17Q GAIN MUTATED | 8 | 27 | 16 |
| 17Q GAIN WILD-TYPE | 48 | 22 | 29 |
Figure S133. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S134. Gene #29: '17q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 17Q GAIN MUTATED | 5 | 0 | 6 | 19 | 10 |
| 17Q GAIN WILD-TYPE | 40 | 8 | 4 | 18 | 8 |
Figure S134. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S135. Gene #29: '17q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 17Q GAIN MUTATED | 5 | 13 | 22 |
| 17Q GAIN WILD-TYPE | 46 | 12 | 20 |
Figure S135. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S136. Gene #29: '17q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17Q GAIN MUTATED | 7 | 23 | 21 |
| 17Q GAIN WILD-TYPE | 63 | 17 | 19 |
Figure S136. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S137. Gene #29: '17q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17Q GAIN MUTATED | 4 | 3 | 6 | 13 | 4 | 15 | 6 |
| 17Q GAIN WILD-TYPE | 39 | 24 | 6 | 11 | 4 | 8 | 7 |
Figure S137. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S138. Gene #29: '17q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 17Q GAIN MUTATED | 4 | 26 | 21 |
| 17Q GAIN WILD-TYPE | 48 | 31 | 20 |
Figure S138. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S139. Gene #29: '17q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17Q GAIN MUTATED | 7 | 22 | 22 |
| 17Q GAIN WILD-TYPE | 63 | 16 | 20 |
Figure S139. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S140. Gene #29: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17Q GAIN MUTATED | 6 | 21 | 24 |
| 17Q GAIN WILD-TYPE | 63 | 15 | 21 |
Figure S140. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S141. Gene #29: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17Q GAIN MUTATED | 2 | 5 | 22 | 22 |
| 17Q GAIN WILD-TYPE | 35 | 28 | 16 | 20 |
Figure S141. Get High-res Image Gene #29: '17q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0101 (Fisher's exact test), Q value = 0.03
Table S142. Gene #31: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19P GAIN MUTATED | 8 | 18 | 10 |
| 19P GAIN WILD-TYPE | 40 | 26 | 48 |
Figure S142. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00011 (Fisher's exact test), Q value = 0.00089
Table S143. Gene #31: '19p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19P GAIN MUTATED | 23 | 3 | 10 |
| 19P GAIN WILD-TYPE | 33 | 46 | 35 |
Figure S143. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00939 (Fisher's exact test), Q value = 0.028
Table S144. Gene #31: '19p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 19P GAIN MUTATED | 20 | 1 | 1 | 5 | 3 |
| 19P GAIN WILD-TYPE | 25 | 7 | 9 | 32 | 15 |
Figure S144. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00318 (Fisher's exact test), Q value = 0.013
Table S145. Gene #31: '19p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 19P GAIN MUTATED | 21 | 3 | 6 |
| 19P GAIN WILD-TYPE | 30 | 22 | 36 |
Figure S145. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-04 (Fisher's exact test), Q value = 0.00083
Table S146. Gene #31: '19p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19P GAIN MUTATED | 28 | 3 | 5 |
| 19P GAIN WILD-TYPE | 42 | 37 | 35 |
Figure S146. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00091 (Fisher's exact test), Q value = 0.005
Table S147. Gene #31: '19p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19P GAIN MUTATED | 14 | 14 | 0 | 4 | 0 | 3 | 1 |
| 19P GAIN WILD-TYPE | 29 | 13 | 12 | 20 | 8 | 20 | 12 |
Figure S147. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0438 (Fisher's exact test), Q value = 0.09
Table S148. Gene #31: '19p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 19P GAIN MUTATED | 18 | 13 | 5 |
| 19P GAIN WILD-TYPE | 34 | 44 | 36 |
Figure S148. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00046
Table S149. Gene #31: '19p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19P GAIN MUTATED | 28 | 2 | 6 |
| 19P GAIN WILD-TYPE | 42 | 36 | 36 |
Figure S149. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00046 (Fisher's exact test), Q value = 0.0028
Table S150. Gene #31: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19P GAIN MUTATED | 27 | 4 | 5 |
| 19P GAIN WILD-TYPE | 42 | 32 | 40 |
Figure S150. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00029
Table S151. Gene #31: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19P GAIN MUTATED | 10 | 18 | 3 | 5 |
| 19P GAIN WILD-TYPE | 27 | 15 | 35 | 37 |
Figure S151. Get High-res Image Gene #31: '19p gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0161 (Fisher's exact test), Q value = 0.041
Table S152. Gene #32: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19Q GAIN MUTATED | 7 | 15 | 7 |
| 19Q GAIN WILD-TYPE | 41 | 29 | 51 |
Figure S152. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 8e-05 (Fisher's exact test), Q value = 0.00068
Table S153. Gene #32: '19q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19Q GAIN MUTATED | 20 | 2 | 7 |
| 19Q GAIN WILD-TYPE | 36 | 47 | 38 |
Figure S153. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00215 (Fisher's exact test), Q value = 0.0098
Table S154. Gene #32: '19q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 19Q GAIN MUTATED | 18 | 0 | 1 | 4 | 1 |
| 19Q GAIN WILD-TYPE | 27 | 8 | 9 | 33 | 17 |
Figure S154. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0026 (Fisher's exact test), Q value = 0.011
Table S155. Gene #32: '19q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 19Q GAIN MUTATED | 18 | 2 | 4 |
| 19Q GAIN WILD-TYPE | 33 | 23 | 38 |
Figure S155. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 4e-05 (Fisher's exact test), Q value = 0.00037
Table S156. Gene #32: '19q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19Q GAIN MUTATED | 24 | 1 | 4 |
| 19Q GAIN WILD-TYPE | 46 | 39 | 36 |
Figure S156. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00062 (Fisher's exact test), Q value = 0.0036
Table S157. Gene #32: '19q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19Q GAIN MUTATED | 11 | 13 | 0 | 3 | 0 | 1 | 1 |
| 19Q GAIN WILD-TYPE | 32 | 14 | 12 | 21 | 8 | 22 | 12 |
Figure S157. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00052
Table S158. Gene #32: '19q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19Q GAIN MUTATED | 24 | 1 | 4 |
| 19Q GAIN WILD-TYPE | 46 | 37 | 38 |
Figure S158. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00033 (Fisher's exact test), Q value = 0.0022
Table S159. Gene #32: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19Q GAIN MUTATED | 23 | 2 | 4 |
| 19Q GAIN WILD-TYPE | 46 | 34 | 41 |
Figure S159. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S160. Gene #32: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19Q GAIN MUTATED | 8 | 16 | 1 | 4 |
| 19Q GAIN WILD-TYPE | 29 | 17 | 37 | 38 |
Figure S160. Get High-res Image Gene #32: '19q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00525 (Fisher's exact test), Q value = 0.018
Table S161. Gene #33: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 20P GAIN MUTATED | 5 | 8 | 21 |
| 20P GAIN WILD-TYPE | 43 | 36 | 37 |
Figure S161. Get High-res Image Gene #33: '20p gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0415 (Fisher's exact test), Q value = 0.086
Table S162. Gene #33: '20p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 20P GAIN MUTATED | 12 | 7 | 15 |
| 20P GAIN WILD-TYPE | 58 | 33 | 25 |
Figure S162. Get High-res Image Gene #33: '20p gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00741 (Fisher's exact test), Q value = 0.024
Table S163. Gene #34: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 20Q GAIN MUTATED | 8 | 8 | 24 |
| 20Q GAIN WILD-TYPE | 40 | 36 | 34 |
Figure S163. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00569 (Fisher's exact test), Q value = 0.019
Table S164. Gene #34: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 20Q GAIN MUTATED | 7 | 16 | 17 |
| 20Q GAIN WILD-TYPE | 49 | 33 | 28 |
Figure S164. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0366 (Fisher's exact test), Q value = 0.078
Table S165. Gene #34: '20q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 20Q GAIN MUTATED | 8 | 10 | 14 |
| 20Q GAIN WILD-TYPE | 43 | 15 | 28 |
Figure S165. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00715 (Fisher's exact test), Q value = 0.023
Table S166. Gene #34: '20q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 20Q GAIN MUTATED | 12 | 10 | 18 |
| 20Q GAIN WILD-TYPE | 58 | 30 | 22 |
Figure S166. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0472 (Fisher's exact test), Q value = 0.095
Table S167. Gene #34: '20q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 20Q GAIN MUTATED | 10 | 13 | 17 |
| 20Q GAIN WILD-TYPE | 42 | 44 | 24 |
Figure S167. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0126 (Fisher's exact test), Q value = 0.034
Table S168. Gene #34: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 20Q GAIN MUTATED | 12 | 10 | 18 |
| 20Q GAIN WILD-TYPE | 58 | 28 | 24 |
Figure S168. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0164 (Fisher's exact test), Q value = 0.041
Table S169. Gene #34: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 20Q GAIN MUTATED | 12 | 9 | 19 |
| 20Q GAIN WILD-TYPE | 57 | 27 | 26 |
Figure S169. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0144 (Fisher's exact test), Q value = 0.038
Table S170. Gene #34: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 20Q GAIN MUTATED | 4 | 8 | 10 | 18 |
| 20Q GAIN WILD-TYPE | 33 | 25 | 28 | 24 |
Figure S170. Get High-res Image Gene #34: '20q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S171. Gene #36: '22q gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 22Q GAIN MUTATED | 9 | 23 | 6 |
| 22Q GAIN WILD-TYPE | 39 | 21 | 52 |
Figure S171. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00134 (Fisher's exact test), Q value = 0.0067
Table S172. Gene #36: '22q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 22Q GAIN MUTATED | 21 | 4 | 13 |
| 22Q GAIN WILD-TYPE | 35 | 45 | 32 |
Figure S172. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00924 (Fisher's exact test), Q value = 0.027
Table S173. Gene #36: '22q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 22Q GAIN MUTATED | 19 | 2 | 2 | 4 | 2 |
| 22Q GAIN WILD-TYPE | 26 | 6 | 8 | 33 | 16 |
Figure S173. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00051 (Fisher's exact test), Q value = 0.0031
Table S174. Gene #36: '22q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 22Q GAIN MUTATED | 21 | 1 | 7 |
| 22Q GAIN WILD-TYPE | 30 | 24 | 35 |
Figure S174. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 3e-05 (Fisher's exact test), Q value = 0.00029
Table S175. Gene #36: '22q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 22Q GAIN MUTATED | 30 | 3 | 5 |
| 22Q GAIN WILD-TYPE | 40 | 37 | 35 |
Figure S175. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S176. Gene #36: '22q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 22Q GAIN MUTATED | 11 | 19 | 1 | 4 | 1 | 1 | 1 |
| 22Q GAIN WILD-TYPE | 32 | 8 | 11 | 20 | 7 | 22 | 12 |
Figure S176. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S177. Gene #36: '22q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 22Q GAIN MUTATED | 30 | 3 | 5 |
| 22Q GAIN WILD-TYPE | 40 | 35 | 37 |
Figure S177. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 6e-05 (Fisher's exact test), Q value = 0.00052
Table S178. Gene #36: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 22Q GAIN MUTATED | 29 | 4 | 5 |
| 22Q GAIN WILD-TYPE | 40 | 32 | 40 |
Figure S178. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S179. Gene #36: '22q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 22Q GAIN MUTATED | 10 | 20 | 3 | 5 |
| 22Q GAIN WILD-TYPE | 27 | 13 | 35 | 37 |
Figure S179. Get High-res Image Gene #36: '22q gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 6e-04 (Fisher's exact test), Q value = 0.0035
Table S180. Gene #37: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XP GAIN MUTATED | 3 | 2 | 17 |
| XP GAIN WILD-TYPE | 45 | 42 | 41 |
Figure S180. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0181 (Fisher's exact test), Q value = 0.045
Table S181. Gene #37: 'xp gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XP GAIN MUTATED | 3 | 8 | 11 |
| XP GAIN WILD-TYPE | 53 | 41 | 34 |
Figure S181. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.039 (Fisher's exact test), Q value = 0.082
Table S182. Gene #37: 'xp gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| XP GAIN MUTATED | 3 | 0 | 2 | 10 | 5 |
| XP GAIN WILD-TYPE | 42 | 8 | 8 | 27 | 13 |
Figure S182. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0088 (Fisher's exact test), Q value = 0.026
Table S183. Gene #37: 'xp gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| XP GAIN MUTATED | 3 | 5 | 12 |
| XP GAIN WILD-TYPE | 48 | 20 | 30 |
Figure S183. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00056 (Fisher's exact test), Q value = 0.0033
Table S184. Gene #37: 'xp gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| XP GAIN MUTATED | 3 | 7 | 12 |
| XP GAIN WILD-TYPE | 67 | 33 | 28 |
Figure S184. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00331 (Fisher's exact test), Q value = 0.013
Table S185. Gene #37: 'xp gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| XP GAIN MUTATED | 2 | 1 | 3 | 7 | 0 | 4 | 5 |
| XP GAIN WILD-TYPE | 41 | 26 | 9 | 17 | 8 | 19 | 8 |
Figure S185. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00084 (Fisher's exact test), Q value = 0.0047
Table S186. Gene #37: 'xp gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| XP GAIN MUTATED | 2 | 7 | 13 |
| XP GAIN WILD-TYPE | 50 | 50 | 28 |
Figure S186. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00017 (Fisher's exact test), Q value = 0.0013
Table S187. Gene #37: 'xp gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| XP GAIN MUTATED | 3 | 5 | 14 |
| XP GAIN WILD-TYPE | 67 | 33 | 28 |
Figure S187. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00173 (Fisher's exact test), Q value = 0.0084
Table S188. Gene #37: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| XP GAIN MUTATED | 3 | 7 | 12 |
| XP GAIN WILD-TYPE | 66 | 29 | 33 |
Figure S188. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00452 (Fisher's exact test), Q value = 0.016
Table S189. Gene #37: 'xp gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XP GAIN MUTATED | 2 | 1 | 7 | 12 |
| XP GAIN WILD-TYPE | 35 | 32 | 31 | 30 |
Figure S189. Get High-res Image Gene #37: 'xp gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00196 (Fisher's exact test), Q value = 0.0091
Table S190. Gene #38: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XQ GAIN MUTATED | 4 | 2 | 16 |
| XQ GAIN WILD-TYPE | 44 | 42 | 42 |
Figure S190. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.018 (Fisher's exact test), Q value = 0.045
Table S191. Gene #38: 'xq gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XQ GAIN MUTATED | 3 | 8 | 11 |
| XQ GAIN WILD-TYPE | 53 | 41 | 34 |
Figure S191. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0212 (Fisher's exact test), Q value = 0.051
Table S192. Gene #38: 'xq gain' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| XQ GAIN MUTATED | 3 | 0 | 4 | 8 | 5 |
| XQ GAIN WILD-TYPE | 42 | 8 | 6 | 29 | 13 |
Figure S192. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0143 (Fisher's exact test), Q value = 0.037
Table S193. Gene #38: 'xq gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| XQ GAIN MUTATED | 3 | 6 | 11 |
| XQ GAIN WILD-TYPE | 48 | 19 | 31 |
Figure S193. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00077 (Fisher's exact test), Q value = 0.0044
Table S194. Gene #38: 'xq gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| XQ GAIN MUTATED | 3 | 7 | 12 |
| XQ GAIN WILD-TYPE | 67 | 33 | 28 |
Figure S194. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00397 (Fisher's exact test), Q value = 0.015
Table S195. Gene #38: 'xq gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| XQ GAIN MUTATED | 2 | 1 | 2 | 7 | 0 | 5 | 5 |
| XQ GAIN WILD-TYPE | 41 | 26 | 10 | 17 | 8 | 18 | 8 |
Figure S195. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00282 (Fisher's exact test), Q value = 0.011
Table S196. Gene #38: 'xq gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| XQ GAIN MUTATED | 2 | 8 | 12 |
| XQ GAIN WILD-TYPE | 50 | 49 | 29 |
Figure S196. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0026
Table S197. Gene #38: 'xq gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| XQ GAIN MUTATED | 3 | 6 | 13 |
| XQ GAIN WILD-TYPE | 67 | 32 | 29 |
Figure S197. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00144 (Fisher's exact test), Q value = 0.0071
Table S198. Gene #38: 'xq gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| XQ GAIN MUTATED | 3 | 7 | 12 |
| XQ GAIN WILD-TYPE | 66 | 29 | 33 |
Figure S198. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0041 (Fisher's exact test), Q value = 0.015
Table S199. Gene #38: 'xq gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XQ GAIN MUTATED | 2 | 1 | 7 | 12 |
| XQ GAIN WILD-TYPE | 35 | 32 | 31 | 30 |
Figure S199. Get High-res Image Gene #38: 'xq gain' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0219 (Fisher's exact test), Q value = 0.052
Table S200. Gene #39: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 1P LOSS MUTATED | 10 | 2 | 6 |
| 1P LOSS WILD-TYPE | 42 | 55 | 35 |
Figure S200. Get High-res Image Gene #39: '1p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0306 (Fisher's exact test), Q value = 0.068
Table S201. Gene #43: '3p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 3P LOSS MUTATED | 11 | 15 | 4 |
| 3P LOSS WILD-TYPE | 45 | 34 | 41 |
Figure S201. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0162 (Fisher's exact test), Q value = 0.041
Table S202. Gene #43: '3p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 3P LOSS MUTATED | 8 | 3 | 2 | 1 | 5 |
| 3P LOSS WILD-TYPE | 37 | 5 | 8 | 36 | 13 |
Figure S202. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00121 (Fisher's exact test), Q value = 0.0064
Table S203. Gene #43: '3p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 3P LOSS MUTATED | 17 | 12 | 1 |
| 3P LOSS WILD-TYPE | 53 | 28 | 39 |
Figure S203. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00317 (Fisher's exact test), Q value = 0.013
Table S204. Gene #43: '3p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 3P LOSS MUTATED | 13 | 4 | 1 | 1 | 1 | 10 | 0 |
| 3P LOSS WILD-TYPE | 30 | 23 | 11 | 23 | 7 | 13 | 13 |
Figure S204. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00122 (Fisher's exact test), Q value = 0.0064
Table S205. Gene #43: '3p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 3P LOSS MUTATED | 13 | 16 | 1 |
| 3P LOSS WILD-TYPE | 39 | 41 | 40 |
Figure S205. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00078 (Fisher's exact test), Q value = 0.0044
Table S206. Gene #43: '3p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 3P LOSS MUTATED | 17 | 12 | 1 |
| 3P LOSS WILD-TYPE | 53 | 26 | 41 |
Figure S206. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00241 (Fisher's exact test), Q value = 0.01
Table S207. Gene #43: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3P LOSS MUTATED | 17 | 11 | 2 |
| 3P LOSS WILD-TYPE | 52 | 25 | 43 |
Figure S207. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00168 (Fisher's exact test), Q value = 0.0082
Table S208. Gene #43: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 3P LOSS MUTATED | 10 | 7 | 12 | 1 |
| 3P LOSS WILD-TYPE | 27 | 26 | 26 | 41 |
Figure S208. Get High-res Image Gene #43: '3p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.047 (Fisher's exact test), Q value = 0.095
Table S209. Gene #44: '3q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 3Q LOSS MUTATED | 7 | 3 | 1 | 1 | 3 |
| 3Q LOSS WILD-TYPE | 38 | 5 | 9 | 36 | 15 |
Figure S209. Get High-res Image Gene #44: '3q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0472 (Fisher's exact test), Q value = 0.095
Table S210. Gene #44: '3q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 3Q LOSS MUTATED | 14 | 6 | 2 |
| 3Q LOSS WILD-TYPE | 55 | 30 | 43 |
Figure S210. Get High-res Image Gene #44: '3q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0454 (Fisher's exact test), Q value = 0.092
Table S211. Gene #45: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 4P LOSS MUTATED | 36 | 35 | 21 |
| 4P LOSS WILD-TYPE | 20 | 14 | 24 |
Figure S211. Get High-res Image Gene #45: '4p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0322 (Fisher's exact test), Q value = 0.071
Table S212. Gene #45: '4p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 4P LOSS MUTATED | 45 | 29 | 18 |
| 4P LOSS WILD-TYPE | 25 | 11 | 22 |
Figure S212. Get High-res Image Gene #45: '4p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0103 (Fisher's exact test), Q value = 0.03
Table S213. Gene #46: '4q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 4Q LOSS MUTATED | 40 | 42 | 26 |
| 4Q LOSS WILD-TYPE | 16 | 7 | 19 |
Figure S213. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0108 (Fisher's exact test), Q value = 0.031
Table S214. Gene #46: '4q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 4Q LOSS MUTATED | 50 | 35 | 23 |
| 4Q LOSS WILD-TYPE | 20 | 5 | 17 |
Figure S214. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0118 (Fisher's exact test), Q value = 0.033
Table S215. Gene #46: '4q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 4Q LOSS MUTATED | 27 | 23 | 10 | 13 | 7 | 21 | 7 |
| 4Q LOSS WILD-TYPE | 16 | 4 | 2 | 11 | 1 | 2 | 6 |
Figure S215. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0157 (Fisher's exact test), Q value = 0.04
Table S216. Gene #46: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 4Q LOSS MUTATED | 36 | 48 | 24 |
| 4Q LOSS WILD-TYPE | 16 | 9 | 17 |
Figure S216. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00502 (Fisher's exact test), Q value = 0.018
Table S217. Gene #46: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 4Q LOSS MUTATED | 50 | 34 | 24 |
| 4Q LOSS WILD-TYPE | 20 | 4 | 18 |
Figure S217. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0352 (Fisher's exact test), Q value = 0.076
Table S218. Gene #46: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 4Q LOSS MUTATED | 50 | 31 | 27 |
| 4Q LOSS WILD-TYPE | 19 | 5 | 18 |
Figure S218. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0257 (Fisher's exact test), Q value = 0.059
Table S219. Gene #46: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 4Q LOSS MUTATED | 24 | 26 | 33 | 25 |
| 4Q LOSS WILD-TYPE | 13 | 7 | 5 | 17 |
Figure S219. Get High-res Image Gene #46: '4q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0273 (Fisher's exact test), Q value = 0.062
Table S220. Gene #47: '5p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 5P LOSS MUTATED | 31 | 7 | 4 | 27 | 7 |
| 5P LOSS WILD-TYPE | 14 | 1 | 6 | 10 | 11 |
Figure S220. Get High-res Image Gene #47: '5p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0404 (Fisher's exact test), Q value = 0.084
Table S221. Gene #48: '5q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 5Q LOSS MUTATED | 33 | 6 | 4 | 26 | 7 |
| 5Q LOSS WILD-TYPE | 12 | 2 | 6 | 11 | 11 |
Figure S221. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0137 (Fisher's exact test), Q value = 0.037
Table S222. Gene #48: '5q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 5Q LOSS MUTATED | 55 | 21 | 25 |
| 5Q LOSS WILD-TYPE | 15 | 19 | 15 |
Figure S222. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00338 (Fisher's exact test), Q value = 0.013
Table S223. Gene #48: '5q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 5Q LOSS MUTATED | 29 | 26 | 8 | 15 | 3 | 12 | 8 |
| 5Q LOSS WILD-TYPE | 14 | 1 | 4 | 9 | 5 | 11 | 5 |
Figure S223. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.03
Table S224. Gene #48: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 5Q LOSS MUTATED | 55 | 19 | 27 |
| 5Q LOSS WILD-TYPE | 15 | 19 | 15 |
Figure S224. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.02 (Fisher's exact test), Q value = 0.049
Table S225. Gene #48: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 5Q LOSS MUTATED | 54 | 19 | 28 |
| 5Q LOSS WILD-TYPE | 15 | 17 | 17 |
Figure S225. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00802 (Fisher's exact test), Q value = 0.025
Table S226. Gene #48: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 5Q LOSS MUTATED | 27 | 28 | 18 | 28 |
| 5Q LOSS WILD-TYPE | 10 | 5 | 20 | 14 |
Figure S226. Get High-res Image Gene #48: '5q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0361 (Fisher's exact test), Q value = 0.077
Table S227. Gene #49: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 6P LOSS MUTATED | 1 | 7 | 5 |
| 6P LOSS WILD-TYPE | 55 | 42 | 40 |
Figure S227. Get High-res Image Gene #49: '6p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0142 (Fisher's exact test), Q value = 0.037
Table S228. Gene #49: '6p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6P LOSS MUTATED | 1 | 2 | 2 | 0 | 1 | 3 | 4 |
| 6P LOSS WILD-TYPE | 42 | 25 | 10 | 24 | 7 | 20 | 9 |
Figure S228. Get High-res Image Gene #49: '6p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00963 (Fisher's exact test), Q value = 0.028
Table S229. Gene #50: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 6Q LOSS MUTATED | 1 | 9 | 6 |
| 6Q LOSS WILD-TYPE | 55 | 40 | 39 |
Figure S229. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0444 (Fisher's exact test), Q value = 0.091
Table S230. Gene #50: '6q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 6Q LOSS MUTATED | 3 | 7 | 6 |
| 6Q LOSS WILD-TYPE | 67 | 33 | 34 |
Figure S230. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00117 (Fisher's exact test), Q value = 0.0062
Table S231. Gene #50: '6q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 6Q LOSS MUTATED | 1 | 2 | 2 | 0 | 2 | 4 | 5 |
| 6Q LOSS WILD-TYPE | 42 | 25 | 10 | 24 | 6 | 19 | 8 |
Figure S231. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0273 (Fisher's exact test), Q value = 0.062
Table S232. Gene #50: '6q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 6Q LOSS MUTATED | 3 | 8 | 5 |
| 6Q LOSS WILD-TYPE | 67 | 30 | 37 |
Figure S232. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0354 (Fisher's exact test), Q value = 0.076
Table S233. Gene #50: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 6Q LOSS MUTATED | 3 | 7 | 6 |
| 6Q LOSS WILD-TYPE | 66 | 29 | 39 |
Figure S233. Get High-res Image Gene #50: '6q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0274 (Fisher's exact test), Q value = 0.062
Table S234. Gene #51: '8p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 8P LOSS MUTATED | 0 | 0 | 0 | 5 | 3 |
| 8P LOSS WILD-TYPE | 45 | 8 | 10 | 32 | 15 |
Figure S234. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00944 (Fisher's exact test), Q value = 0.028
Table S235. Gene #51: '8p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 8P LOSS MUTATED | 0 | 4 | 4 |
| 8P LOSS WILD-TYPE | 51 | 21 | 38 |
Figure S235. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.0103 (Fisher's exact test), Q value = 0.03
Table S236. Gene #51: '8p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8P LOSS MUTATED | 1 | 5 | 6 |
| 8P LOSS WILD-TYPE | 69 | 35 | 34 |
Figure S236. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.047 (Fisher's exact test), Q value = 0.095
Table S237. Gene #51: '8p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8P LOSS MUTATED | 1 | 0 | 1 | 3 | 1 | 3 | 3 |
| 8P LOSS WILD-TYPE | 42 | 27 | 11 | 21 | 7 | 20 | 10 |
Figure S237. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00853 (Fisher's exact test), Q value = 0.026
Table S238. Gene #51: '8p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8P LOSS MUTATED | 1 | 3 | 8 |
| 8P LOSS WILD-TYPE | 51 | 54 | 33 |
Figure S238. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00207 (Fisher's exact test), Q value = 0.0095
Table S239. Gene #51: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8P LOSS MUTATED | 1 | 3 | 8 |
| 8P LOSS WILD-TYPE | 69 | 35 | 34 |
Figure S239. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0074 (Fisher's exact test), Q value = 0.024
Table S240. Gene #51: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8P LOSS MUTATED | 1 | 4 | 7 |
| 8P LOSS WILD-TYPE | 68 | 32 | 38 |
Figure S240. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0226 (Fisher's exact test), Q value = 0.053
Table S241. Gene #51: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8P LOSS MUTATED | 1 | 0 | 4 | 7 |
| 8P LOSS WILD-TYPE | 36 | 33 | 34 | 35 |
Figure S241. Get High-res Image Gene #51: '8p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0242 (Fisher's exact test), Q value = 0.057
Table S242. Gene #52: '8q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 8Q LOSS MUTATED | 0 | 1 | 4 |
| 8Q LOSS WILD-TYPE | 56 | 48 | 41 |
Figure S242. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0143 (Fisher's exact test), Q value = 0.037
Table S243. Gene #52: '8q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 8Q LOSS MUTATED | 0 | 3 | 1 |
| 8Q LOSS WILD-TYPE | 51 | 22 | 41 |
Figure S243. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00237 (Fisher's exact test), Q value = 0.01
Table S244. Gene #52: '8q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 70 | 40 | 35 |
Figure S244. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0121 (Fisher's exact test), Q value = 0.033
Table S245. Gene #52: '8q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 8Q LOSS MUTATED | 0 | 0 | 0 | 3 | 0 | 0 | 2 |
| 8Q LOSS WILD-TYPE | 43 | 27 | 12 | 21 | 8 | 23 | 11 |
Figure S245. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00132 (Fisher's exact test), Q value = 0.0067
Table S246. Gene #52: '8q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 52 | 57 | 36 |
Figure S246. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00226 (Fisher's exact test), Q value = 0.01
Table S247. Gene #52: '8q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 70 | 38 | 37 |
Figure S247. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0029 (Fisher's exact test), Q value = 0.012
Table S248. Gene #52: '8q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 8Q LOSS MUTATED | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 69 | 36 | 40 |
Figure S248. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00335 (Fisher's exact test), Q value = 0.013
Table S249. Gene #52: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 8Q LOSS MUTATED | 0 | 0 | 0 | 5 |
| 8Q LOSS WILD-TYPE | 37 | 33 | 38 | 37 |
Figure S249. Get High-res Image Gene #52: '8q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0323 (Fisher's exact test), Q value = 0.071
Table S250. Gene #53: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 9P LOSS MUTATED | 15 | 16 | 32 |
| 9P LOSS WILD-TYPE | 33 | 28 | 26 |
Figure S250. Get High-res Image Gene #53: '9p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00028 (Fisher's exact test), Q value = 0.002
Table S251. Gene #54: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 9Q LOSS MUTATED | 11 | 13 | 34 |
| 9Q LOSS WILD-TYPE | 37 | 31 | 24 |
Figure S251. Get High-res Image Gene #54: '9q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0185 (Fisher's exact test), Q value = 0.046
Table S252. Gene #54: '9q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 9Q LOSS MUTATED | 13 | 10 | 8 | 13 | 0 | 11 | 3 |
| 9Q LOSS WILD-TYPE | 30 | 17 | 4 | 11 | 8 | 12 | 10 |
Figure S252. Get High-res Image Gene #54: '9q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0207 (Fisher's exact test), Q value = 0.05
Table S253. Gene #55: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 10P LOSS MUTATED | 20 | 19 | 38 |
| 10P LOSS WILD-TYPE | 28 | 25 | 20 |
Figure S253. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00037 (Fisher's exact test), Q value = 0.0024
Table S254. Gene #55: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 10P LOSS MUTATED | 20 | 36 | 21 |
| 10P LOSS WILD-TYPE | 36 | 13 | 24 |
Figure S254. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0083 (Fisher's exact test), Q value = 0.026
Table S255. Gene #55: '10p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 10P LOSS MUTATED | 16 | 3 | 4 | 24 | 14 |
| 10P LOSS WILD-TYPE | 29 | 5 | 6 | 13 | 4 |
Figure S255. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00682 (Fisher's exact test), Q value = 0.022
Table S256. Gene #55: '10p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 10P LOSS MUTATED | 18 | 15 | 28 |
| 10P LOSS WILD-TYPE | 33 | 10 | 14 |
Figure S256. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 3e-04 (Fisher's exact test), Q value = 0.0021
Table S257. Gene #55: '10p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 10P LOSS MUTATED | 27 | 31 | 19 |
| 10P LOSS WILD-TYPE | 43 | 9 | 21 |
Figure S257. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.0055 (Fisher's exact test), Q value = 0.019
Table S258. Gene #55: '10p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 10P LOSS MUTATED | 16 | 11 | 9 | 13 | 6 | 18 | 4 |
| 10P LOSS WILD-TYPE | 27 | 16 | 3 | 11 | 2 | 5 | 9 |
Figure S258. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0382 (Fisher's exact test), Q value = 0.081
Table S259. Gene #55: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 10P LOSS MUTATED | 20 | 36 | 21 |
| 10P LOSS WILD-TYPE | 32 | 21 | 20 |
Figure S259. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00085 (Fisher's exact test), Q value = 0.0047
Table S260. Gene #55: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 10P LOSS MUTATED | 27 | 29 | 21 |
| 10P LOSS WILD-TYPE | 43 | 9 | 21 |
Figure S260. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00209 (Fisher's exact test), Q value = 0.0095
Table S261. Gene #55: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 10P LOSS MUTATED | 27 | 27 | 23 |
| 10P LOSS WILD-TYPE | 42 | 9 | 22 |
Figure S261. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00127 (Fisher's exact test), Q value = 0.0065
Table S262. Gene #55: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 10P LOSS MUTATED | 12 | 15 | 29 | 21 |
| 10P LOSS WILD-TYPE | 25 | 18 | 9 | 21 |
Figure S262. Get High-res Image Gene #55: '10p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00878 (Fisher's exact test), Q value = 0.026
Table S263. Gene #56: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 10Q LOSS MUTATED | 19 | 16 | 37 |
| 10Q LOSS WILD-TYPE | 29 | 28 | 21 |
Figure S263. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S264. Gene #56: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 10Q LOSS MUTATED | 16 | 36 | 20 |
| 10Q LOSS WILD-TYPE | 40 | 13 | 25 |
Figure S264. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00018 (Fisher's exact test), Q value = 0.0013
Table S265. Gene #56: '10q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 10Q LOSS MUTATED | 24 | 30 | 18 |
| 10Q LOSS WILD-TYPE | 46 | 10 | 22 |
Figure S265. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00229 (Fisher's exact test), Q value = 0.01
Table S266. Gene #56: '10q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 10Q LOSS MUTATED | 16 | 8 | 9 | 12 | 5 | 18 | 4 |
| 10Q LOSS WILD-TYPE | 27 | 19 | 3 | 12 | 3 | 5 | 9 |
Figure S266. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0322 (Fisher's exact test), Q value = 0.071
Table S267. Gene #56: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 10Q LOSS MUTATED | 18 | 34 | 20 |
| 10Q LOSS WILD-TYPE | 34 | 23 | 21 |
Figure S267. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0026
Table S268. Gene #56: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 10Q LOSS MUTATED | 24 | 28 | 20 |
| 10Q LOSS WILD-TYPE | 46 | 10 | 22 |
Figure S268. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00123 (Fisher's exact test), Q value = 0.0064
Table S269. Gene #56: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 10Q LOSS MUTATED | 24 | 26 | 22 |
| 10Q LOSS WILD-TYPE | 45 | 10 | 23 |
Figure S269. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00139 (Fisher's exact test), Q value = 0.0069
Table S270. Gene #56: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 10Q LOSS MUTATED | 12 | 12 | 28 | 20 |
| 10Q LOSS WILD-TYPE | 25 | 21 | 10 | 22 |
Figure S270. Get High-res Image Gene #56: '10q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00854 (Fisher's exact test), Q value = 0.026
Table S271. Gene #57: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 11P LOSS MUTATED | 25 | 36 | 37 |
| 11P LOSS WILD-TYPE | 23 | 8 | 21 |
Figure S271. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00039 (Fisher's exact test), Q value = 0.0025
Table S272. Gene #57: '11p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 11P LOSS MUTATED | 54 | 28 | 16 |
| 11P LOSS WILD-TYPE | 16 | 12 | 24 |
Figure S272. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00055 (Fisher's exact test), Q value = 0.0033
Table S273. Gene #57: '11p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 11P LOSS MUTATED | 32 | 22 | 8 | 12 | 4 | 18 | 2 |
| 11P LOSS WILD-TYPE | 11 | 5 | 4 | 12 | 4 | 5 | 11 |
Figure S273. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00103 (Fisher's exact test), Q value = 0.0056
Table S274. Gene #57: '11p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 11P LOSS MUTATED | 38 | 43 | 17 |
| 11P LOSS WILD-TYPE | 14 | 14 | 24 |
Figure S274. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00041 (Fisher's exact test), Q value = 0.0026
Table S275. Gene #57: '11p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 11P LOSS MUTATED | 54 | 27 | 17 |
| 11P LOSS WILD-TYPE | 16 | 11 | 25 |
Figure S275. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00178 (Fisher's exact test), Q value = 0.0085
Table S276. Gene #57: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 11P LOSS MUTATED | 53 | 25 | 20 |
| 11P LOSS WILD-TYPE | 16 | 11 | 25 |
Figure S276. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00125 (Fisher's exact test), Q value = 0.0064
Table S277. Gene #57: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 11P LOSS MUTATED | 28 | 26 | 27 | 17 |
| 11P LOSS WILD-TYPE | 9 | 7 | 11 | 25 |
Figure S277. Get High-res Image Gene #57: '11p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S278. Gene #58: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 11Q LOSS MUTATED | 30 | 44 | 41 |
| 11Q LOSS WILD-TYPE | 18 | 0 | 17 |
Figure S278. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 9e-05 (Fisher's exact test), Q value = 0.00076
Table S279. Gene #58: '11q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 11Q LOSS MUTATED | 62 | 32 | 21 |
| 11Q LOSS WILD-TYPE | 8 | 8 | 19 |
Figure S279. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S280. Gene #58: '11q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 11Q LOSS MUTATED | 35 | 27 | 11 | 15 | 6 | 18 | 3 |
| 11Q LOSS WILD-TYPE | 8 | 0 | 1 | 9 | 2 | 5 | 10 |
Figure S280. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00062 (Fisher's exact test), Q value = 0.0036
Table S281. Gene #58: '11q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 11Q LOSS MUTATED | 44 | 49 | 22 |
| 11Q LOSS WILD-TYPE | 8 | 8 | 19 |
Figure S281. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00014 (Fisher's exact test), Q value = 0.0011
Table S282. Gene #58: '11q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 11Q LOSS MUTATED | 62 | 31 | 22 |
| 11Q LOSS WILD-TYPE | 8 | 7 | 20 |
Figure S282. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00108 (Fisher's exact test), Q value = 0.0058
Table S283. Gene #58: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 11Q LOSS MUTATED | 61 | 28 | 26 |
| 11Q LOSS WILD-TYPE | 8 | 8 | 19 |
Figure S283. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S284. Gene #58: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 11Q LOSS MUTATED | 29 | 33 | 30 | 23 |
| 11Q LOSS WILD-TYPE | 8 | 0 | 8 | 19 |
Figure S284. Get High-res Image Gene #58: '11q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0442 (Fisher's exact test), Q value = 0.091
Table S285. Gene #59: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 13Q LOSS MUTATED | 34 | 39 | 40 |
| 13Q LOSS WILD-TYPE | 14 | 5 | 18 |
Figure S285. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0327 (Fisher's exact test), Q value = 0.071
Table S286. Gene #59: '13q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 13Q LOSS MUTATED | 58 | 31 | 24 |
| 13Q LOSS WILD-TYPE | 12 | 9 | 16 |
Figure S286. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00111 (Fisher's exact test), Q value = 0.0059
Table S287. Gene #59: '13q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 13Q LOSS MUTATED | 31 | 27 | 11 | 14 | 6 | 17 | 7 |
| 13Q LOSS WILD-TYPE | 12 | 0 | 1 | 10 | 2 | 6 | 6 |
Figure S287. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0451 (Fisher's exact test), Q value = 0.092
Table S288. Gene #59: '13q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 13Q LOSS MUTATED | 43 | 45 | 25 |
| 13Q LOSS WILD-TYPE | 9 | 12 | 16 |
Figure S288. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0231 (Fisher's exact test), Q value = 0.054
Table S289. Gene #59: '13q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 13Q LOSS MUTATED | 58 | 30 | 25 |
| 13Q LOSS WILD-TYPE | 12 | 8 | 17 |
Figure S289. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0014 (Fisher's exact test), Q value = 0.007
Table S290. Gene #59: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 13Q LOSS MUTATED | 26 | 32 | 29 | 26 |
| 13Q LOSS WILD-TYPE | 11 | 1 | 9 | 16 |
Figure S290. Get High-res Image Gene #59: '13q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00079 (Fisher's exact test), Q value = 0.0045
Table S291. Gene #60: '14q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 14Q LOSS MUTATED | 2 | 14 | 4 |
| 14Q LOSS WILD-TYPE | 54 | 35 | 41 |
Figure S291. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0277 (Fisher's exact test), Q value = 0.063
Table S292. Gene #60: '14q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 14Q LOSS MUTATED | 3 | 1 | 1 | 4 | 7 |
| 14Q LOSS WILD-TYPE | 42 | 7 | 9 | 33 | 11 |
Figure S292. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.0043 (Fisher's exact test), Q value = 0.016
Table S293. Gene #60: '14q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 14Q LOSS MUTATED | 3 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 67 | 30 | 33 |
Figure S293. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 5e-05 (Fisher's exact test), Q value = 0.00046
Table S294. Gene #60: '14q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 14Q LOSS MUTATED | 0 | 3 | 0 | 5 | 0 | 10 | 2 |
| 14Q LOSS WILD-TYPE | 43 | 24 | 12 | 19 | 8 | 13 | 11 |
Figure S294. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0308 (Fisher's exact test), Q value = 0.068
Table S295. Gene #60: '14q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 14Q LOSS MUTATED | 2 | 11 | 7 |
| 14Q LOSS WILD-TYPE | 50 | 46 | 34 |
Figure S295. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.00322 (Fisher's exact test), Q value = 0.013
Table S296. Gene #60: '14q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 14Q LOSS MUTATED | 3 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 67 | 28 | 35 |
Figure S296. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00247 (Fisher's exact test), Q value = 0.01
Table S297. Gene #60: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 14Q LOSS MUTATED | 3 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 66 | 26 | 38 |
Figure S297. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.0109 (Fisher's exact test), Q value = 0.031
Table S298. Gene #60: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 14Q LOSS MUTATED | 1 | 2 | 10 | 7 |
| 14Q LOSS WILD-TYPE | 36 | 31 | 28 | 35 |
Figure S298. Get High-res Image Gene #60: '14q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00548 (Fisher's exact test), Q value = 0.019
Table S299. Gene #61: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 15Q LOSS MUTATED | 11 | 2 | 16 |
| 15Q LOSS WILD-TYPE | 37 | 42 | 42 |
Figure S299. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 3e-05 (Fisher's exact test), Q value = 0.00029
Table S300. Gene #61: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 15Q LOSS MUTATED | 1 | 17 | 11 |
| 15Q LOSS WILD-TYPE | 55 | 32 | 34 |
Figure S300. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S301. Gene #61: '15q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 15Q LOSS MUTATED | 0 | 0 | 4 | 14 | 7 |
| 15Q LOSS WILD-TYPE | 45 | 8 | 6 | 23 | 11 |
Figure S301. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S302. Gene #61: '15q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 15Q LOSS MUTATED | 0 | 10 | 15 |
| 15Q LOSS WILD-TYPE | 51 | 15 | 27 |
Figure S302. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S303. Gene #61: '15q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 15Q LOSS MUTATED | 1 | 13 | 15 |
| 15Q LOSS WILD-TYPE | 69 | 27 | 25 |
Figure S303. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S304. Gene #61: '15q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 15Q LOSS MUTATED | 0 | 1 | 3 | 7 | 4 | 8 | 6 |
| 15Q LOSS WILD-TYPE | 43 | 26 | 9 | 17 | 4 | 15 | 7 |
Figure S304. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S305. Gene #61: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 15Q LOSS MUTATED | 0 | 14 | 15 |
| 15Q LOSS WILD-TYPE | 52 | 43 | 26 |
Figure S305. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S306. Gene #61: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 15Q LOSS MUTATED | 1 | 13 | 15 |
| 15Q LOSS WILD-TYPE | 69 | 25 | 27 |
Figure S306. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S307. Gene #61: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 15Q LOSS MUTATED | 1 | 12 | 16 |
| 15Q LOSS WILD-TYPE | 68 | 24 | 29 |
Figure S307. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S308. Gene #61: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 15Q LOSS MUTATED | 0 | 1 | 13 | 15 |
| 15Q LOSS WILD-TYPE | 37 | 32 | 25 | 27 |
Figure S308. Get High-res Image Gene #61: '15q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00599 (Fisher's exact test), Q value = 0.02
Table S309. Gene #62: '16p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 16P LOSS MUTATED | 17 | 21 | 6 |
| 16P LOSS WILD-TYPE | 39 | 28 | 39 |
Figure S309. Get High-res Image Gene #62: '16p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00855 (Fisher's exact test), Q value = 0.026
Table S310. Gene #62: '16p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16P LOSS MUTATED | 12 | 25 | 7 |
| 16P LOSS WILD-TYPE | 40 | 32 | 34 |
Figure S310. Get High-res Image Gene #62: '16p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0112 (Fisher's exact test), Q value = 0.032
Table S311. Gene #62: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 16P LOSS MUTATED | 19 | 18 | 7 |
| 16P LOSS WILD-TYPE | 51 | 20 | 35 |
Figure S311. Get High-res Image Gene #62: '16p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0307 (Fisher's exact test), Q value = 0.068
Table S312. Gene #63: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 16Q LOSS MUTATED | 13 | 27 | 11 |
| 16Q LOSS WILD-TYPE | 39 | 30 | 30 |
Figure S312. Get High-res Image Gene #63: '16q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S313. Gene #64: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17P LOSS MUTATED | 5 | 23 | 9 |
| 17P LOSS WILD-TYPE | 43 | 21 | 49 |
Figure S313. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0405 (Fisher's exact test), Q value = 0.084
Table S314. Gene #64: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 17P LOSS MUTATED | 18 | 6 | 13 |
| 17P LOSS WILD-TYPE | 38 | 43 | 32 |
Figure S314. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0443 (Fisher's exact test), Q value = 0.091
Table S315. Gene #64: '17p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 17P LOSS MUTATED | 17 | 2 | 1 | 7 | 1 |
| 17P LOSS WILD-TYPE | 28 | 6 | 9 | 30 | 17 |
Figure S315. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 0.00321 (Fisher's exact test), Q value = 0.013
Table S316. Gene #64: '17p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 17P LOSS MUTATED | 19 | 1 | 8 |
| 17P LOSS WILD-TYPE | 32 | 24 | 34 |
Figure S316. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 0.00462 (Fisher's exact test), Q value = 0.016
Table S317. Gene #64: '17p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17P LOSS MUTATED | 26 | 5 | 6 |
| 17P LOSS WILD-TYPE | 44 | 35 | 34 |
Figure S317. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.00024 (Fisher's exact test), Q value = 0.0017
Table S318. Gene #64: '17p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17P LOSS MUTATED | 10 | 16 | 2 | 1 | 0 | 4 | 4 |
| 17P LOSS WILD-TYPE | 33 | 11 | 10 | 23 | 8 | 19 | 9 |
Figure S318. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.00314 (Fisher's exact test), Q value = 0.013
Table S319. Gene #64: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17P LOSS MUTATED | 26 | 4 | 7 |
| 17P LOSS WILD-TYPE | 44 | 34 | 35 |
Figure S319. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00168 (Fisher's exact test), Q value = 0.0082
Table S320. Gene #64: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17P LOSS MUTATED | 26 | 3 | 8 |
| 17P LOSS WILD-TYPE | 43 | 33 | 37 |
Figure S320. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S321. Gene #64: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17P LOSS MUTATED | 7 | 19 | 3 | 8 |
| 17P LOSS WILD-TYPE | 30 | 14 | 35 | 34 |
Figure S321. Get High-res Image Gene #64: '17p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00581 (Fisher's exact test), Q value = 0.02
Table S322. Gene #65: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 17Q LOSS MUTATED | 1 | 10 | 5 |
| 17Q LOSS WILD-TYPE | 47 | 34 | 53 |
Figure S322. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.0198 (Fisher's exact test), Q value = 0.049
Table S323. Gene #65: '17q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 17Q LOSS MUTATED | 13 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 57 | 38 | 39 |
Figure S323. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.029 (Fisher's exact test), Q value = 0.065
Table S324. Gene #65: '17q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 17Q LOSS MUTATED | 5 | 8 | 0 | 0 | 0 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 38 | 19 | 12 | 24 | 8 | 21 | 12 |
Figure S324. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 0.0146 (Fisher's exact test), Q value = 0.038
Table S325. Gene #65: '17q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 17Q LOSS MUTATED | 13 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 57 | 36 | 41 |
Figure S325. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0107 (Fisher's exact test), Q value = 0.031
Table S326. Gene #65: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 17Q LOSS MUTATED | 13 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 56 | 34 | 44 |
Figure S326. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 0.00489 (Fisher's exact test), Q value = 0.017
Table S327. Gene #65: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 17Q LOSS MUTATED | 4 | 9 | 2 | 1 |
| 17Q LOSS WILD-TYPE | 33 | 24 | 36 | 41 |
Figure S327. Get High-res Image Gene #65: '17q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0432 (Fisher's exact test), Q value = 0.089
Table S328. Gene #66: '18p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 18P LOSS MUTATED | 53 | 36 | 27 |
| 18P LOSS WILD-TYPE | 17 | 4 | 13 |
Figure S328. Get High-res Image Gene #66: '18p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 0.016 (Fisher's exact test), Q value = 0.041
Table S329. Gene #66: '18p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 18P LOSS MUTATED | 53 | 35 | 28 |
| 18P LOSS WILD-TYPE | 17 | 3 | 14 |
Figure S329. Get High-res Image Gene #66: '18p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.032 (Fisher's exact test), Q value = 0.071
Table S330. Gene #67: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 18Q LOSS MUTATED | 58 | 35 | 29 |
| 18Q LOSS WILD-TYPE | 12 | 3 | 13 |
Figure S330. Get High-res Image Gene #67: '18q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.0205 (Fisher's exact test), Q value = 0.05
Table S331. Gene #67: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 18Q LOSS MUTATED | 27 | 31 | 34 | 30 |
| 18Q LOSS WILD-TYPE | 10 | 2 | 4 | 12 |
Figure S331. Get High-res Image Gene #67: '18q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S332. Gene #68: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19P LOSS MUTATED | 12 | 5 | 33 |
| 19P LOSS WILD-TYPE | 36 | 39 | 25 |
Figure S332. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S333. Gene #68: '19p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19P LOSS MUTATED | 2 | 31 | 17 |
| 19P LOSS WILD-TYPE | 54 | 18 | 28 |
Figure S333. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S334. Gene #68: '19p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 19P LOSS MUTATED | 2 | 2 | 4 | 21 | 12 |
| 19P LOSS WILD-TYPE | 43 | 6 | 6 | 16 | 6 |
Figure S334. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S335. Gene #68: '19p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 19P LOSS MUTATED | 2 | 14 | 25 |
| 19P LOSS WILD-TYPE | 49 | 11 | 17 |
Figure S335. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S336. Gene #68: '19p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19P LOSS MUTATED | 2 | 27 | 21 |
| 19P LOSS WILD-TYPE | 68 | 13 | 19 |
Figure S336. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S337. Gene #68: '19p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19P LOSS MUTATED | 0 | 2 | 9 | 12 | 5 | 16 | 6 |
| 19P LOSS WILD-TYPE | 43 | 25 | 3 | 12 | 3 | 7 | 7 |
Figure S337. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S338. Gene #68: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 19P LOSS MUTATED | 1 | 28 | 21 |
| 19P LOSS WILD-TYPE | 51 | 29 | 20 |
Figure S338. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S339. Gene #68: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19P LOSS MUTATED | 2 | 27 | 21 |
| 19P LOSS WILD-TYPE | 68 | 11 | 21 |
Figure S339. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S340. Gene #68: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19P LOSS MUTATED | 2 | 24 | 24 |
| 19P LOSS WILD-TYPE | 67 | 12 | 21 |
Figure S340. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S341. Gene #68: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19P LOSS MUTATED | 0 | 2 | 26 | 22 |
| 19P LOSS WILD-TYPE | 37 | 31 | 12 | 20 |
Figure S341. Get High-res Image Gene #68: '19p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S342. Gene #69: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 19Q LOSS MUTATED | 11 | 7 | 35 |
| 19Q LOSS WILD-TYPE | 37 | 37 | 23 |
Figure S342. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S343. Gene #69: '19q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 19Q LOSS MUTATED | 1 | 34 | 18 |
| 19Q LOSS WILD-TYPE | 55 | 15 | 27 |
Figure S343. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S344. Gene #69: '19q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 19Q LOSS MUTATED | 1 | 2 | 4 | 22 | 14 |
| 19Q LOSS WILD-TYPE | 44 | 6 | 6 | 15 | 4 |
Figure S344. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S345. Gene #69: '19q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 19Q LOSS MUTATED | 1 | 14 | 28 |
| 19Q LOSS WILD-TYPE | 50 | 11 | 14 |
Figure S345. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S346. Gene #69: '19q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 19Q LOSS MUTATED | 1 | 30 | 22 |
| 19Q LOSS WILD-TYPE | 69 | 10 | 18 |
Figure S346. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S347. Gene #69: '19q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 19Q LOSS MUTATED | 0 | 1 | 9 | 13 | 5 | 19 | 6 |
| 19Q LOSS WILD-TYPE | 43 | 26 | 3 | 11 | 3 | 4 | 7 |
Figure S347. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S348. Gene #69: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 19Q LOSS MUTATED | 1 | 30 | 22 |
| 19Q LOSS WILD-TYPE | 51 | 27 | 19 |
Figure S348. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S349. Gene #69: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 19Q LOSS MUTATED | 1 | 30 | 22 |
| 19Q LOSS WILD-TYPE | 69 | 8 | 20 |
Figure S349. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S350. Gene #69: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 19Q LOSS MUTATED | 1 | 27 | 25 |
| 19Q LOSS WILD-TYPE | 68 | 9 | 20 |
Figure S350. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S351. Gene #69: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 19Q LOSS MUTATED | 0 | 1 | 29 | 23 |
| 19Q LOSS WILD-TYPE | 37 | 32 | 9 | 19 |
Figure S351. Get High-res Image Gene #69: '19q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.0157 (Fisher's exact test), Q value = 0.04
Table S352. Gene #70: '20p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 20P LOSS MUTATED | 5 | 18 | 7 |
| 20P LOSS WILD-TYPE | 47 | 39 | 34 |
Figure S352. Get High-res Image Gene #70: '20p loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0274 (Fisher's exact test), Q value = 0.062
Table S353. Gene #70: '20p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 20P LOSS MUTATED | 3 | 8 | 13 | 6 |
| 20P LOSS WILD-TYPE | 34 | 25 | 25 | 36 |
Figure S353. Get High-res Image Gene #70: '20p loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00234 (Fisher's exact test), Q value = 0.01
Table S354. Gene #72: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| 22Q LOSS MUTATED | 9 | 9 | 27 |
| 22Q LOSS WILD-TYPE | 39 | 35 | 31 |
Figure S354. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S355. Gene #72: '22q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| 22Q LOSS MUTATED | 4 | 28 | 13 |
| 22Q LOSS WILD-TYPE | 52 | 21 | 32 |
Figure S355. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00022 (Fisher's exact test), Q value = 0.0016
Table S356. Gene #72: '22q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 |
|---|---|---|---|---|---|
| ALL | 45 | 8 | 10 | 37 | 18 |
| 22Q LOSS MUTATED | 4 | 1 | 5 | 16 | 9 |
| 22Q LOSS WILD-TYPE | 41 | 7 | 5 | 21 | 9 |
Figure S356. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #3: 'RPPA_CNMF'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S357. Gene #72: '22q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 51 | 25 | 42 |
| 22Q LOSS MUTATED | 4 | 15 | 16 |
| 22Q LOSS WILD-TYPE | 47 | 10 | 26 |
Figure S357. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #4: 'RPPA_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S358. Gene #72: '22q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 40 | 40 |
| 22Q LOSS MUTATED | 6 | 23 | 16 |
| 22Q LOSS WILD-TYPE | 64 | 17 | 24 |
Figure S358. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #5: 'MRNASEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S359. Gene #72: '22q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 | CLUS_5 | CLUS_6 | CLUS_7 |
|---|---|---|---|---|---|---|---|
| ALL | 43 | 27 | 12 | 24 | 8 | 23 | 13 |
| 22Q LOSS MUTATED | 5 | 1 | 7 | 10 | 4 | 13 | 5 |
| 22Q LOSS WILD-TYPE | 38 | 26 | 5 | 14 | 4 | 10 | 8 |
Figure S359. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #6: 'MRNASEQ_CHIERARCHICAL'
P value = 2e-05 (Fisher's exact test), Q value = 2e-04
Table S360. Gene #72: '22q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| 22Q LOSS MUTATED | 4 | 24 | 17 |
| 22Q LOSS WILD-TYPE | 48 | 33 | 24 |
Figure S360. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S361. Gene #72: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| 22Q LOSS MUTATED | 6 | 21 | 18 |
| 22Q LOSS WILD-TYPE | 64 | 17 | 24 |
Figure S361. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S362. Gene #72: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 69 | 36 | 45 |
| 22Q LOSS MUTATED | 6 | 19 | 20 |
| 22Q LOSS WILD-TYPE | 63 | 17 | 25 |
Figure S362. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #9: 'MIRSEQ_MATURE_CNMF'
P value = 1e-05 (Fisher's exact test), Q value = 0.00012
Table S363. Gene #72: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| 22Q LOSS MUTATED | 4 | 2 | 21 | 18 |
| 22Q LOSS WILD-TYPE | 33 | 31 | 17 | 24 |
Figure S363. Get High-res Image Gene #72: '22q loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00234 (Fisher's exact test), Q value = 0.01
Table S364. Gene #73: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XP LOSS MUTATED | 2 | 11 | 16 |
| XP LOSS WILD-TYPE | 46 | 33 | 42 |
Figure S364. Get High-res Image Gene #73: 'xp loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00175 (Fisher's exact test), Q value = 0.0084
Table S365. Gene #73: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XP LOSS MUTATED | 6 | 6 | 17 |
| XP LOSS WILD-TYPE | 50 | 43 | 28 |
Figure S365. Get High-res Image Gene #73: 'xp loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.00352 (Fisher's exact test), Q value = 0.013
Table S366. Gene #73: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XP LOSS MUTATED | 2 | 9 | 4 | 14 |
| XP LOSS WILD-TYPE | 35 | 24 | 34 | 28 |
Figure S366. Get High-res Image Gene #73: 'xp loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
P value = 0.00019 (Fisher's exact test), Q value = 0.0014
Table S367. Gene #74: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 48 | 44 | 58 |
| XQ LOSS MUTATED | 1 | 11 | 17 |
| XQ LOSS WILD-TYPE | 47 | 33 | 41 |
Figure S367. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #1: 'CN_CNMF'
P value = 0.00187 (Fisher's exact test), Q value = 0.0088
Table S368. Gene #74: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 56 | 49 | 45 |
| XQ LOSS MUTATED | 6 | 6 | 17 |
| XQ LOSS WILD-TYPE | 50 | 43 | 28 |
Figure S368. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #2: 'METHLYATION_CNMF'
P value = 0.0254 (Fisher's exact test), Q value = 0.059
Table S369. Gene #74: 'xq loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 52 | 57 | 41 |
| XQ LOSS MUTATED | 7 | 8 | 14 |
| XQ LOSS WILD-TYPE | 45 | 49 | 27 |
Figure S369. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #7: 'MIRSEQ_CNMF'
P value = 0.0266 (Fisher's exact test), Q value = 0.061
Table S370. Gene #74: 'xq loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 |
|---|---|---|---|
| ALL | 70 | 38 | 42 |
| XQ LOSS MUTATED | 11 | 4 | 14 |
| XQ LOSS WILD-TYPE | 59 | 34 | 28 |
Figure S370. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #8: 'MIRSEQ_CHIERARCHICAL'
P value = 0.00393 (Fisher's exact test), Q value = 0.015
Table S371. Gene #74: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
| nPatients | CLUS_1 | CLUS_2 | CLUS_3 | CLUS_4 |
|---|---|---|---|---|
| ALL | 37 | 33 | 38 | 42 |
| XQ LOSS MUTATED | 2 | 9 | 4 | 14 |
| XQ LOSS WILD-TYPE | 35 | 24 | 34 | 28 |
Figure S371. Get High-res Image Gene #74: 'xq loss' versus Molecular Subtype #10: 'MIRSEQ_MATURE_CHIERARCHICAL'
-
Copy number data file = broad_values_by_arm.txt from GISTIC pipeline
-
Processed Copy number data file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_Correlate_Genomic_Events_Preprocess/TGCT-TP/19781848/transformed.cor.cli.txt
-
Molecular subtypes file = /xchip/cga/gdac-prod/tcga-gdac/jobResults/GDAC_mergedClustering/TGCT-TP/20140863/TGCT-TP.transferedmergedcluster.txt
-
Number of patients = 150
-
Number of significantly arm-level cnvs = 74
-
Number of molecular subtypes = 10
-
Exclude genes that fewer than K tumors have mutations, K = 3
For binary or multi-class clinical features (nominal or ordinal), two-tailed Fisher's exact tests (Fisher 1922) were used to estimate the P values using the 'fisher.test' function in R
For multiple hypothesis correction, Q value is the False Discovery Rate (FDR) analogue of the P value (Benjamini and Hochberg 1995), defined as the minimum FDR at which the test may be called significant. We used the 'Benjamini and Hochberg' method of 'p.adjust' function in R to convert P values into Q values.