Clustering of RPPA data: consensus hierarchical
Breast Invasive Carcinoma (Primary solid tumor)
21 August 2015  |  analyses__2015_08_21
Maintainer Information
Citation Information
Maintained by Hailei Zhang (Broad Institute)
Cite as Broad Institute TCGA Genome Data Analysis Center (2015): Clustering of RPPA data: consensus hierarchical. Broad Institute of MIT and Harvard. doi:10.7908/C1JM28T2
- Overview
+ Introduction
- Summary

Median absolute deviation (MAD) was used to select 142 most variable proteins. Consensus ward linkage hierarchical clustering of 410 samples and 142 proteins identified 6 subtypes with the stability of the clustering increasing for k = 2 to k = 10.

- Results
+ Protein expression patterns of molecular subtypes
+ Silhouette widths, Cophenetic Correlation Coefficients and Consensus matrix
+ Samples assignment with silhouette width
+ Marker proteins of each subtype
+ Methods & Data