type count De_novo_Start_InFrame 3 De_novo_Start_OutOfFrame 13 Frame_Shift_Del 2219 Frame_Shift_Ins 1579 In_Frame_Del 427 In_Frame_Ins 103 Missense_Mutation 44009 Nonsense_Mutation 3571 Nonstop_Mutation 52 Silent 16064 Splice_Site 2327 Start_Codon_Del 6 Start_Codon_Ins 4 Start_Codon_SNP 47 Stop_Codon_Del 2 Stop_Codon_Ins 3 Total 70429